tetradecanoylphorbol acetate has been researched along with cyclosporine in 210 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (0.95) | 18.7374 |
| 1990's | 142 (67.62) | 18.2507 |
| 2000's | 54 (25.71) | 29.6817 |
| 2010's | 12 (5.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Daniels, MJ; Dean, JH; Selgrade, MK | 1 |
| Kamoun, M; Kant, JA; Kim, HW; Makni, H; Moolten, DM; Williams, TM | 1 |
| Andersson, J; Andersson, U; Groth, CG; Nagy, S | 1 |
| Kincaid, RL; O'Keefe, SJ; O'Neill, EA; Tamura, J; Tocci, MJ | 1 |
| Cohen, N; Dawson, TM; Fotuhi, M; Glatt, CE; Snowman, AM; Snyder, SH; Steiner, JP | 1 |
| Avruch, J; Bierer, BE; Calvo, V; Grove, JR; Price, DJ | 1 |
| Liu, J; Sakane, T; Tsunematsu, T | 1 |
| Gschwendt, M; Kittstein, W; Lindner, D; Marks, F | 1 |
| Hardy, SJ; Haylock, DN; Lopez, AF; Murray, AW | 1 |
| Borger, P; Dokter, WH; Halie, MR; Hendriks, D; van der Horst, I; Vellenga, E | 1 |
| Brown, DA; Diamond, DJ; Kondo, KL; Wong, SW | 1 |
| Cherwinski, HM; Ransom, JT; Semenuk, GT | 1 |
| Alonso, JL; Alonso, MA; Campanero, MR; Pivel, JP; Sánchez-Madrid, F; Santis, AG; Tugores, A; Yagüe, E | 1 |
| Cacalano, NA; Chen, BX; Cleveland, WL; Erlanger, BF | 1 |
| Garcia-Sanz, JA; Lichtenheld, MG; Lu, P; Podack, ER | 1 |
| Best, L; Martin, F; Trebilcock, R | 1 |
| Baldari, CT; Heguy, A; Macchia, G; Melli, M; Telford, JL | 1 |
| Chiara, MD; Foot, AB; Jones, OT; Sobrino, F | 1 |
| Hart, MK; Haynes, BF; Ware, RE | 1 |
| Damle, NK; Eberhardt, C; Van der Vieren, M | 1 |
| Semerjian, A; Su, MS | 1 |
| Cairns, JS; Mainwaring, MS; McCarthy, SA | 1 |
| Gaur, A; Scott, DW; Warner, GL | 1 |
| Duell, EA; Elder, JT; Esmann, J; Fisher, GJ; Gupta, AK; Nickoloff, BJ; Talwar, HS; Voorhees, JJ | 1 |
| Gschwendt, M; Kittstein, W; Marks, F | 1 |
| Clipstone, NA; Crabtree, GR | 1 |
| Bonnefoy-Berard, N; Dearden-Badet, MT; Genestier, L; Lizard, G; Revillard, JP | 1 |
| Alexander, D; Metcalfe, S; Turner, J | 1 |
| Mouzaki, A; Rungger, D | 1 |
| Anel, A; Boyer, C; Buferne, M; Golstein, P; Schmitt-Verhulst, AM | 1 |
| Ortega, G; Parker, L; Shearer, WT; Smith, CS | 1 |
| Heike, T; Jung, EY; Kawai, M; Mayumi, M; Nishikomori, R; Tai, G; Yamanaka, C | 1 |
| Kaldjian, EP; Stoolman, LM | 1 |
| Higer, M; Teutsch, M; Wang, D; Wortis, HW | 1 |
| Ito, K; Kaminuma, O; Kobayashi, S; Matsuzaki, G; Mori, A; Nishizaki, Y; Okudaira, H; Suko, M; Tsuruoka, N; Yamamoto, K | 1 |
| Bonnefoy-Berard, N; Flacher, M; Genestier, L; Revillard, JP; Rouault, JP | 1 |
| Calnan, BJ; Cheng, L; Lina, A; Szychowski, S; Winoto, A; Woronicz, JD | 1 |
| Bohmann, D; Cockerill, PN; Jenkins, F; Shannon, MF | 1 |
| Benacerraf, B; Freeman, GJ; Galvin, F; Nadler, L; Razi-Wolf, Z; Reiser, H | 1 |
| Duquesnoy, RJ; Fung, JJ; Starzl, TE; Todo, S; Venkataramanan, R; Yao, GZ; Zeevi, A | 1 |
| Allison, JP; Davidson, WF; Giese, T | 1 |
| Bertrand, R; Jenkins, J; Pommier, Y; Solary, E | 1 |
| Bates, SE; Dickstein, B; Fojo, AT; Lee, JS; Spolyar, M | 1 |
| Bondada, S; Muthukkumar, S; Udhayakumar, V | 1 |
| Bell, M; Huntoon, C; McKean, DJ; Nilson, A; Paya, C; Podzorski, R; Rastogi, S; Van Norstrand, M | 1 |
| Clark, GJ; Dallman, MJ; Hünig, T; Tacke, M | 1 |
| Barkis, I; Degiannis, D; Hadjiyannaki-Koniavitou, K; Hornung, N; Raskova, J; Vareltzides, A | 1 |
| Ahern, D; Alberg, DG; Belshaw, PJ; Fuleihan, R; Geha, RS; Harmon, W; Horner, A; Ramesh, N; Stamenkovic, I | 1 |
| Dokter, WH; Stulp, BK; Van Straaten, JF; Vellenga, E | 1 |
| Batiuk, TD; Halloran, PF; Yatscoff, RW | 1 |
| Menezes, J; Tanner, JE | 1 |
| Argentieri, D; Barbone, AG; Lau, CY; Ritchie, D; Wang, EY; Zhou, L | 1 |
| Lai, JH; Tan, TH | 1 |
| Kähäri, VM; Keski-Oja, J; Lohi, J | 1 |
| Copeland, KF; Goudsmit, J; Haaksma, AG; Heeney, JL | 1 |
| Welsh, N | 1 |
| Grünbaum, L; Hummel, R; Schächtele, C; Seifert, R; Wenzel-Seifert, K | 1 |
| Chen, D; Rothenberg, EV | 1 |
| Biassoni, R; Cambiaggi, A; Cantoni, C; Ferrini, S; Poggi, A; Sforzini, S; Viale, M | 1 |
| Conde, M; Gualberto, A; Sobrino, F | 1 |
| Brecha, N; Corey, JL; Davidson, N; Lester, HA; Quick, MW | 1 |
| Naora, H; Young, IG | 1 |
| Ben-Neriah, Y; Hibi, M; Jacinto, E; Kallunki, T; Karin, M; Su, B | 1 |
| Clark, EA; Firpo, EJ; Liang, HA; Polacino, PS | 1 |
| Cacchione, RN; Cairns, JS; Mainwaring, MS; McCarthy, SA; Walker, JA | 1 |
| Kemp, A; Tang, M | 1 |
| Benz, EJ; Chambers, SK; Gilmore-Hebert, M; Kacinski, BM; Rodov, S; Wang, Y | 1 |
| Kitamura, K; Sawada, S; Suzuki, G; Takaku, F | 1 |
| Chong, AS; Finnegan, A; Foster, P; Gebel, H; Jiang, X; Sankary, HN; Williams, JW | 1 |
| Dokter, WH; Esselink, MT; Halie, MR; Sierdsema, SJ; Vellenga, E | 1 |
| Bravo, R; Kroczek, RA; Mages, HW; Rilke, O; Stamminger, T | 1 |
| Campbell, HD; Wang, Y; Young, IG | 1 |
| Baldari, CT; Heguy, A; Telford, JL | 1 |
| Felipo, V; Grisolía, S; Kosenko, E; Marcaida, G; Miñana, MD | 1 |
| Brooks, N; Ryffel, B; Willcocks, JL; Woerly, G | 1 |
| Siegel, JN; Taylor-Fishwick, DA | 1 |
| Lipsky, PE; Nishioka, J; Nishioka, Y; Splawski, JB | 1 |
| Handschumacher, RE; Li, W | 1 |
| Frosch, KH; Kalden, JR; Lane, P; Manger, B; Nüsslein, HG; Woith, W | 1 |
| Converse, PJ; Esa, AH | 1 |
| Li, W; Mondino, A; Mueller, DL; Whaley, CD | 1 |
| Berchtold, MW; Döbbeling, U | 1 |
| Sheppard, KE | 1 |
| Batiuk, TD; Enns, J; Halloran, PF; Pazderka, F | 1 |
| Ciccarelli, A; Cirillo, R; de Crescenzo, G; de Paulis, A; Marone, G; Patella, V | 1 |
| Novick, RP; Schlievert, PM; Witcher, KJ | 1 |
| Conde, M; Montaño, R; Moreno-Aurioles, VR; Ramirez, R; Sanchez-Madrid, F; Sanchez-Mateos, P; Sobrino, F | 1 |
| del Castillo-Olivares, A; Esteban del Valle, A; Márquez, J; Medina, MA; Núñez de Castro, I | 1 |
| Beaver, J; Waring, P | 1 |
| Ichida, T; Obinata, T; Takuma, T; Tamura, S; Yokoyama, N | 1 |
| Branch, DW; Dudley, DJ; Edwin, SS; Mitchell, MD; Scott, JR; Silver, RM | 1 |
| Young, HA | 1 |
| Chen, CY; Faller, DV; Forman, LW | 1 |
| Auphan, N; Schmitt-Verhulst, AM; Simon, AK | 1 |
| Cory, S; Huang, DC; Strasser, A | 1 |
| Goldstone, SD; Hunt, NH | 1 |
| Kim, BK; Kim, HW; Kim, RS | 1 |
| Asakura, Y; Hosino, A; Kaminuma, O; Mikami, T; Mori, A; Nagahori, T; Nishizaki, Y; Ohmura, T; Okudaira, H; Suko, M | 1 |
| Bobe, R; Bredoux, R; Enouf, J; Kovàcs, T; Lacabaratz-Porret, C; Launay, S; Papp, B | 1 |
| Aoki, Y; Kao, PN | 1 |
| Abraham, JM; Balcer-Kubiczek, EK; Han, LH; Harrison, GH; Meltzer, SJ; Shi, ZM; Zhang, XF | 1 |
| Hirai, H; Kanda, Y; Mitani, K; Ueno, H; Yamagata, T; Yazaki, Y | 1 |
| Avots, A; Cimanis, A; Flory, E; Hoffmeyer, A; Rapp, UR; Serfling, E | 1 |
| Puigneró, V; Queralt, J | 1 |
| Rogers, AM; Russell, JH; Thilenius, AR | 1 |
| Arron, J; Choi, Y; Wong, B | 1 |
| Cebrat, M; Gaymes, TJ; Kay, JE; Siemion, IZ | 1 |
| Haberl, I; Hamilton, G; Schaufler, K; Swatonek, H; Thalhammer, T; Theyer, G; Ulsperger, E; Wenzl, E | 1 |
| Koyasu, S; Matsuda, S; Moriguchi, T; Nishida, E | 1 |
| Malavasi, F; Morra, M; Sancho, J; Terhorst, C; Zubiaur, M | 1 |
| Asanuma, M; Asanuma, SN; Gómez-Vargas, M; Iida, K; Iwata, E; Miyazaki, I; Nakanishi, T; Ogawa, N | 1 |
| Cardoso, CM; De Meis, L; Rumjanek, VM | 1 |
| Ireland, J; Meyer, KB | 1 |
| Chen, CY; Del Gatto-Konczak, F; Karin, M; Wu, Z | 1 |
| Kim, BK; Kim, HW; Lee, EJ; Shim, MJ | 1 |
| Chow, SC; Jondal, M; Osorio, LM; Rottenberg, M | 1 |
| Reinach, PS; Torres-zamorano, V; Wu, X; Yang, H | 1 |
| McIntyre, BW; Woodside, DG | 1 |
| Abbott, KL; Boss, V; Murphy, TJ; Pavlath, GK; Wang, XF | 1 |
| Coy, J; Hekele, A; Krammer, PH; Laur, O; Li-Weber, M; Walczak, H | 1 |
| Degiannis, D; Kapsalis, A; Koniavitou, K; Thalassinos, A | 1 |
| Abbal, M; Durand, D; Ohayon, E; Peres, C; Puyoo, O; Rostaing, L; Tkaczuk, J | 1 |
| Bondada, S; Elliott, L; Johnston, TD; Nagabhushan, M; Ranjan, D; Wu, G | 1 |
| Fisher, GJ; Reynolds, NJ; Voorhees, JJ | 1 |
| Azuma, H; Ichimaru, N; Kokado, Y; Li, BS; Matsumiya, K; Miki, T; Nonomura, N; Okuyama, A; Suzuki, S; Takahara, S; Wang, JD | 1 |
| Accornero, P; Carè, A; Chiodoni, C; Colombo, MP; Kurrle, R; Mattia, G; Radrizzani, M | 1 |
| Fujimoto, M; Nagasaka, Y; Nakamura, K; Tanaka, T | 1 |
| Antonsson, A; Grundstrøm, T; Hughes, K | 1 |
| Bostick-Bruton, F; Li, Q; Reed, E; Tsang, B | 1 |
| Chang, DM; Chang, ML; Ho, LJ; Lai, JH; Lee, TC | 1 |
| Alvarez-Escola, C; Alvarez-Mon, M; De La Hera, A; Diaz, D; Guillen, C; Prieto, A; Reyes, E; San Antonio, E | 1 |
| Aoki, Y; Kao, PN; Nazarian, S; Ng, JC; Qiu, D; Shi, L; Uyei, A; Zhao, G | 1 |
| Davis, JR; Ray, DW; Reem, GH | 1 |
| Boulougouris, G; Ellwood, CN; McLeod, JD; Patel, YI; Sansom, DM; Walker, LS | 1 |
| Aikawa, R; Komuro, I; Nagai, R; Saito, S; Shiojima, I; Yazaki, Y | 1 |
| Alvarez-Cermeño, JC; Alvarez-Mon, M; de la Piedra, M; Gimeno, A; Guillen, C; Prieto, A | 1 |
| Adler, G; Algül, H; Schmid, RM; Tando, Y; Wagner, M; Weidenbach, H | 1 |
| Ahlers, C; Kreideweiss, S; Nordheim, A; Rühlmann, A | 1 |
| Almawi, WY; Assi, JW; Chudzik, DM; Lazarovits, AI | 1 |
| De Boer, ML; Kees, UR; Mordvinov, VA; Peroni, SE; Sanderson, CJ | 1 |
| Chang, DM; Ho, LJ; Kwan, CY; Lai, JH; Lee, TC | 1 |
| Hampel, G; Hosseini, R; Jung, K | 1 |
| Alam, T; Hamawy, MM; Knechtle, SJ; Manthei, ER; Tsuchida, M | 1 |
| Chwalinska-Sadowska, H; Klimczak, E; Koc, A; Ksiezopolska-Pietrzak, K; Luszczykiewicz, G; Maslinski, W; Ziolkowska, M | 1 |
| Arellano, JL; de Cabo, MR; García, JE; López, AJ; López, AM; Losada, JP; Rodríguez, FM; Sarmiento, RG | 1 |
| Cahalan, MD; Chandy, KG; Grissmer, S; Hansel, W; Miller, MJ; Wulff, H | 1 |
| Bakker, AQ; Hooijberg, E; Ruizendaal, JJ; Spits, H | 1 |
| García-Rodríguez, C; Rao, A | 1 |
| Garlington, S; Khavari, PA; Kirschberg, T; Kreider, E; Lin, Q; McGrane, PL; Rothbard, JB; Wender, PA | 1 |
| Fong, CW; Lin, SC; Neo, SY; Zhang, Y | 1 |
| Arellano, JL; de Cabo, MR; Garcia, JE; López, AJ; Losada, JP; Rodríguez, FM | 1 |
| Bullens, DM; Ceuppens, J; Charitidou, L; Kasran, A; Lorré, K; Rafiq, K; van Gool, SW | 1 |
| Aboud, M; Ben-Aroya, Z; Flügel, RM; Löchelt, M; Mor-Vaknin, N; Torgeman, A; Zelin, E | 1 |
| Li, JM; Lin, ZB | 1 |
| Blauvelt, A; Davis, DA; Moses, AV; Orenstein, JM; Overwijk, WW; Rinderknecht, AS; Yarchoan, R; Zoeteweij, JP | 1 |
| Barbeau, B; Fortin, JF; Lemieux, AM; Paré , ME; Robichaud, GA; Tremblay, MJ | 1 |
| Depledge, P; Dhanjal, N; Foxwell, B; Manic, A; Moore, M; Rawlins, P; Sadeghi, R; Wrigley, S | 1 |
| Bordin, G; Brunelleschi, S; Colangelo, D; Lavagno, L; Viano, I | 1 |
| Barten, MJ; Gummert, JF; Morris, RE; Shorthouse, R; van Gelder, T | 1 |
| Barbin, L; Cariani, A; Dovigo, L; Fabbri, E; Muccinelli, M; Spisani, S; Trotta, F | 1 |
| Gnegy, ME; McGinnis, KM; Mukerjee, N; Wang, KK | 1 |
| Altavilla, D; Bazzani, C; Bertolini, A; Galeano, M; Guarini, S; Saitta, A; Santamaria, LB; Squadrito, F; Squadrito, G; Venuti, FS | 1 |
| Agut, H; Calvez, V; Dupin, N; Huraux, JM; Marcelin, AG; Milliancourt, C; Wirden, M | 1 |
| Asano, Y; Ishibashi, S; Miyata, Y; Muto, S; Okada, K | 1 |
| Celluzzi, C; Moreno, J; Shi, Y; Tondravi, M; Wang, R; Zhang, L; Zhang, X | 1 |
| Al-Daraji, WI; Grant, KR; Reynolds, NJ; Ryan, K; Saxton, A | 1 |
| Ahn, JS; Ahn, SC; Choe, YK; Kang, DO; Kim, BY; Mheen, TI; Oh, WK; Park, YM | 1 |
| Han, SW; Henrique-Silva, F; Machado-Santelli, GM; Pfister, SC | 1 |
| Bengtén, E; Chinchar, VG; Clem, LW; Miller, NW; Park, H; Wilson, M; Zhou, H | 1 |
| Abal, AT; Abul, HT; Haines, DD; Mahmoud, FF; Wise, JA | 1 |
| Degiannis, D; Hatziagelaki, E; Koniavitou, K; Raptis, S; Tsiavou, A | 1 |
| Izumo, S; Ma, Q; Pu, WT | 1 |
| Bernoin, M; Lefèvre, F; Marcelo, P | 1 |
| Göke, B; Groblewski, GE; Krzykowski, KJ; Schäfer, C; Steffen, H | 1 |
| Bryl, E; Lisowska, K; Soroczyńska, M; Witkowski, JM | 1 |
| Cao, X; Ishiguro, N; Kambe, F; Mitsuyama, H; Murakami, R; Seo, H | 1 |
| Bryl, E; Jóźwik, A; Soroczyńska, M; Witkowski, JM | 1 |
| Childs, T; Davé, V; Whitsett, JA | 1 |
| Cao, X; Kambe, F; Mitsuyama, H; Murakami, R; Nagaya, T; Saito, K; Seo, H; Wakabayashi, K; Yoshida, J | 1 |
| Aronson, LR; Drobatz, KJ; Hunter, CA; Mason, N | 1 |
| Bagi, Z; Blumberg, PM; Edes, I; Kedei, N; Lizanecz, E; Papp, Z; Pásztor, ET; Tóth, A | 1 |
| Adiri, Y; Boss, JM; Evavold, BD; Kumar, S; Lukacher, AE; Skeen, MJ; Vezys, VD; Yoon, H; Ziegler, HK | 1 |
| Canellada, A; Cano, E; Redondo, JM; Sánchez-Ruiloba, L; Zafra, F | 1 |
| Barten, MJ; Bocsi, J; Boldt, A; Dhein, S; Garbade, J; Gummert, JF; Mohr, FW; Rahmel, A | 1 |
| Toker, A; Yiu, GK | 1 |
| Cha, SH; Kang, HS; Ko, CB; Lee, BS; Paik, SG; Sul, D | 1 |
| Böhler, T; Budde, K; Glander, P; Gurragchaa, P; Kamar, N; Klupp, J; Neumayer, HH; Nolting, J; Reisener, K | 1 |
| Lian, ZX; Shu, SA; Wu, T; Yi, H; Zeng, C; Zhao, Y; Zhen, Y | 1 |
| Brune, K; Clauss, T; Nitsche, A; Pahl, A; Siegert, W; Zhang, M | 1 |
| Gu, X; Liu, J; St Clair, DK; Zhao, Y | 1 |
| Iijima, M; Oguro, T; Sueki, H; Yajima, Y; Yoshida, T | 1 |
| Chen, CF; Chiang, LL; Kao, SJ; Lee, CN; Lo, SL; Su, CL; Wang, D | 1 |
| Hirasawa, N; Hong, J; Ishihara, K; Katoh, G; Ohsawa, Y; Ohuchi, K; Seyama, T; Shibata, K; Tamura, S | 1 |
| Choi, JJ; Hwang, ES; Jin, M; Kim, DH; Kim, JS; Park, BK; Park, S; Yun, CY | 1 |
| Freidel, K; Rauch, BH; Rosenkranz, AC; Schrör, K | 1 |
| Hantash, BM; Reeves, JP; Thomas, AP; Turner, JD | 1 |
| Agarwal, SK; Bharti, AC; Bhowmik, DM; Guleria, S; Gupta, N; Kumar, R; Mehra, NK; Panigrahi, A; Sharma, PK; Shukla, S | 1 |
| Baumgrass, R; Bendfeldt, H; Brandt, C; Liman, P; Mueller, K; Radbruch, A; Reinke, P; Worm, M | 1 |
| Camperio, C; Caristi, S; Costanzo, A; Del Porto, P; Mantel, PY; Piccolella, E; Schmidt-Weber, CB; Scottà, C; Soligo, M | 1 |
| Hirasawa, N; Ohuchi, K | 1 |
| Bachmann, M; Mühl, H; Pfeilschifter, J; Rudloff, I | 1 |
| Evers, BM; Guo, Z; Wang, Q; Weiss, HL; Zhou, Y | 1 |
| Chen, H; Ge, CH; Huang, R; Li, CY; Yang, XM; Yin, RH; Yu, M; Zhan, YQ; Zhang, JH; Zhao, L | 1 |
| Choi, S; Jeon, BH; Joo, HK; Kang, G; Kim, CS; Lee, YR; Park, JB; Ryoo, S | 1 |
| Archer, TM; Fellman, CL; Lunsford, KV; Mackin, AJ; Stokes, JV; Wills, RW | 1 |
| Asai, M; Iwata, N; Kawakubo, T; Kimura, S; Kinjo, A; Maruyama, K; Mori, R; Shirotani, K; Yagishita, S | 1 |
| Archer, TM; Dandrieux, JRS; Firestone, S; Mansfield, CS; Narayanan, L | 1 |
3 review(s) available for tetradecanoylphorbol acetate and cyclosporine
| Article | Year |
|---|---|
Regulation of interferon-gamma gene expression.
Topics: Animals; Cyclosporine; DNA; DNA-Binding Proteins; Enhancer Elements, Genetic; Erythroid-Specific DNA-Binding Factors; Gene Expression Regulation; Glucocorticoids; Humans; Interferon-gamma; Ionomycin; Leukemia-Lymphoma, Adult T-Cell; Lymphocyte Activation; Lymphocyte Subsets; Methylation; Mice; NF-kappa B; Phytohemagglutinins; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1996 |
Enhanced production and gene expression of IL-5 in bronchial asthma. Possible management of atopic diseases with IL-5 specific gene transcription inhibitor.
Topics: Animals; Asthma; CD4-Positive T-Lymphocytes; Cyclosporine; Gene Expression; Humans; Interleukin-5; Ionomycin; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1996 |
[Roles of histamine in the exacerbated allergic dermatitis].
Topics: Animals; Cyclosporine; Dermatitis, Atopic; Disease Models, Animal; Drug Therapy, Combination; Histamine; Histamine Antagonists; Humans; Mice; Picryl Chloride; Piperidines; Pyrilamine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H3; Receptors, Histamine H4; Tetradecanoylphorbol Acetate | 2011 |
2 trial(s) available for tetradecanoylphorbol acetate and cyclosporine
| Article | Year |
|---|---|
Mechanisms of rapid induction of interleukin-22 in activated T cells and its modulation by cyclosporin a.
Topics: Autoimmune Diseases; Calcimycin; Calcium Ionophores; Carcinogens; Cyclosporine; Female; Gene Expression Regulation; Humans; I-kappa B Kinase; Immunosuppressive Agents; Interleukin-22; Interleukins; Jurkat Cells; Lymphocyte Activation; Male; Response Elements; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors | 2012 |
Effects of oral cyclosporine on canine T-cell expression of IL-2 and IFN-gamma across a 12-h dosing interval.
Topics: Administration, Oral; Animals; Cyclosporine; Dogs; Drug Administration Schedule; Flow Cytometry; Gene Expression Regulation; Immunosuppressive Agents; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Real-Time Polymerase Chain Reaction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2016 |
205 other study(ies) available for tetradecanoylphorbol acetate and cyclosporine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Correlation between chemical suppression of natural killer cell activity in mice and susceptibility to cytomegalovirus: rationale for applying murine cytomegalovirus as a host resistance model and for interpreting immunotoxicity testing in terms of risk o
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cadmium; Cadmium Chloride; Cells, Cultured; Chlorides; Cyclophosphamide; Cyclosporine; Cytomegalovirus Infections; Disease Susceptibility; Female; G(M1) Ganglioside; Immunity, Cellular; Immunosuppressive Agents; Killer Cells, Natural; Mice; Mice, Inbred C3H; Nickel; Polychlorinated Dibenzodioxins; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate | 1992 |
CD28-stimulated IL-2 gene expression in Jurkat T cells occurs in part transcriptionally and is cyclosporine-A sensitive.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD2 Antigens; CD28 Antigens; Cell Line; Cyclosporine; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; Interleukin-2; Promoter Regions, Genetic; Receptors, Immunologic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
FK 506 and cyclosporine inhibit antigen- or mitogen-induced monokine and lymphokine production in vitro.
Topics: Cells, Cultured; Cyclosporine; Cytokines; Dose-Response Relationship, Drug; Enterotoxins; Fluorescent Antibody Technique; Humans; Interferon-gamma; Interleukin-2; Interleukin-4; Interleukin-5; Ionomycin; Kinetics; Leukocytes, Mononuclear; Lymphokines; Lymphotoxin-alpha; Staphylococcus aureus; Tacrolimus; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin.
Topics: Animals; Calcineurin; Calmodulin-Binding Proteins; Cell Line; Chloramphenicol O-Acetyltransferase; Chromosome Deletion; Cyclosporine; Gene Expression Regulation; Humans; Interleukin-2; Ionomycin; Kinetics; Macromolecular Substances; Mice; Phosphoprotein Phosphatases; Polymerase Chain Reaction; Promoter Regions, Genetic; Recombinant Proteins; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1992 |
High brain densities of the immunophilin FKBP colocalized with calcineurin.
Topics: Adenosine Triphosphate; Animals; Autoradiography; Brain; Calcineurin; Calcium; Calmodulin-Binding Proteins; Carrier Proteins; Cell Membrane; Cyclosporine; Molecular Weight; Organ Specificity; PC12 Cells; Phosphoprotein Phosphatases; Phosphorylation; Rats; Sulfur Radioisotopes; Tacrolimus; Tacrolimus Binding Proteins; Tetradecanoylphorbol Acetate; Tritium | 1992 |
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chromatography, Ion Exchange; Cyclosporine; Immunosuppressive Agents; Insulin; Kinetics; Liver Neoplasms, Experimental; Polyenes; Protein Kinase Inhibitors; Protein Kinases; Recombinant Proteins; Ribosomal Protein S6 Kinases; Ribosomes; Sirolimus; Tacrolimus; Tetradecanoylphorbol Acetate; Transfection | 1992 |
The effects of FK-506 and cyclosporin A on the proliferation of PHA-stimulated T cells in response to IL-2, IL-4 or IL-6.
Topics: Cells, Cultured; Cyclosporine; Humans; Interleukins; Kinetics; Lymphocyte Activation; Phytohemagglutinins; Signal Transduction; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate | 1992 |
Differential inhibition by staurosporine of phorbol ester, bryostatin and okadaic acid effects on mouse skin.
Topics: Alkaloids; Animals; Bryostatins; Cyclosporine; Edema; Ethers, Cyclic; Female; Lactones; Macrolides; Mice; Okadaic Acid; Protein Kinase C; Skin; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Examination of the role of the proteolytically-activated form of protein kinase C in the differentiation of human haemopoietic cells.
Topics: Biological Transport; Bone Marrow; Bone Marrow Cells; Calcitriol; Calcium; Cell Differentiation; Cells, Cultured; Cyclosporine; Dimethyl Sulfoxide; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Macrophages; Monocytes; Neutrophils; Peptide Hydrolases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
Interleukin-4 (IL-4) receptor expression on human T cells is affected by different intracellular signaling pathways and by IL-4 at transcriptional and posttranscriptional level.
Topics: Calcimycin; Calcium; Cells, Cultured; Concanavalin A; Cycloheximide; Cyclosporine; Dactinomycin; Gene Expression Regulation; Humans; Interleukin-4; Receptors, Interleukin-4; Receptors, Mitogen; RNA Processing, Post-Transcriptional; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
Characterization of nuclear protein binding to the interferon-gamma promoter in quiescent and activated human T cells.
Topics: Base Sequence; Binding, Competitive; Cell Nucleus; Chromosome Deletion; Cyclosporine; DNA; Humans; Interferon-gamma; Lymphocyte Activation; Molecular Sequence Data; Mutagenesis; Nuclear Proteins; Organ Specificity; Phytohemagglutinins; Promoter Regions, Genetic; Protein Binding; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
Stimulation of a T helper cell class 2 clone with immobilized anti-T cell receptor antibody activates a Ca2+ and protein kinase C-independent lethal signaling pathway.
Topics: Animals; Calcium; CD4 Antigens; Cell Survival; Clone Cells; Cyclosporine; Dexamethasone; Interleukin-1; Interleukin-4; Lymphocyte Activation; Mice; Mice, Inbred C3H; Protein Kinase C; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1992 |
Tumor necrosis factor-alpha production induced in T lymphocytes through the AIM/CD69 activation pathway.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Cyclosporine; Female; Lectins, C-Type; Mice; Mice, Inbred BALB C; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Evidence for a functional receptor for cyclosporin A on the surface of lymphocytes.
Topics: Animals; B-Lymphocytes; Cell Line; Cell Membrane; Cyclosporine; Humans; Immunosuppression Therapy; Interleukin-2; Kinetics; Lymphocytes; Mice; Receptors, Immunologic; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
Perforin expression in human peripheral blood mononuclear cells. Definition of an IL-2-independent pathway of perforin induction in CD8+ T cells.
Topics: Base Sequence; Calcimycin; Calcium; CD8 Antigens; Cell Adhesion; Cyclosporine; Emetine; Gene Expression; Granzymes; Humans; Interleukin-2; Leukocytes, Mononuclear; Membrane Glycoproteins; Membrane Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides; Perforin; Pore Forming Cytotoxic Proteins; RNA, Messenger; Serine Endopeptidases; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Effects of cyclosporin A on induced HIT cell alkalinization.
Topics: Animals; Cell Line; Cyclosporine; Cytosol; Hydrogen-Ion Concentration; Ionomycin; Islets of Langerhans; Potassium Chloride; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
Cyclosporin A blocks calcium-dependent pathways of gene activation.
Topics: Calcium; Cyclosporine; Egtazic Acid; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-2; Phytohemagglutinins; Promoter Regions, Genetic; Receptors, Immunologic; Receptors, Interleukin-1; Signal Transduction; Simian virus 40; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured | 1991 |
Differential effect of cyclosporine A on respiratory burst by several types of human leukocytic cells.
Topics: Cyclosporine; Humans; Leukocytes; Macrophages; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Induction of T cell CD7 gene transcription by nonmitogenic ionomycin-induced transmembrane calcium flux.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Calcium; CD2 Antigens; CD3 Complex; Cyclosporine; Cytokines; Half-Life; Humans; Ionomycin; Phytohemagglutinins; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Receptors, Immunologic; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Up-Regulation | 1991 |
Direct interaction with primed CD4+ CD45R0+ memory T lymphocytes induces expression of endothelial leukocyte adhesion molecule-1 and vascular cell adhesion molecule-1 on the surface of vascular endothelial cells.
Topics: Antigens, CD; CD4-Positive T-Lymphocytes; CD8 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cyclosporine; E-Selectin; Endothelium, Vascular; Histocompatibility Antigens; Humans; Immunologic Memory; Intercellular Adhesion Molecule-1; Leukocyte Common Antigens; Lymphocyte Activation; Lymphocyte Subsets; Lymphokines; Tetradecanoylphorbol Acetate; Vascular Cell Adhesion Molecule-1 | 1991 |
Activation of transcription factor NF kappa B in Jurkat cells is inhibited selectively by FK 506 in a signal-dependent manner.
Topics: Base Sequence; Cell Line; Cyclosporine; Humans; Immunosuppressive Agents; Ionomycin; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Polyenes; Signal Transduction; Sirolimus; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Effects of FK 506 and cyclosporine on T-cell tolerance: inhibition of a "protective" mechanism that regulates activation-induced apoptosis in developing thymocytes.
Topics: Animals; Calcimycin; Cell Death; Cells, Cultured; Cyclosporine; DNA; Immune Tolerance; Mice; Mice, Inbred C57BL; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate | 1991 |
A polyclonal model for B-cell tolerance. II. Linkage between signaling of B-cell egress from G0, class II upregulation and unresponsiveness.
Topics: Animals; Antigens, Differentiation; B-Lymphocytes; Concanavalin A; Cyclosporine; Histocompatibility Antigens Class II; Immune Tolerance; Interleukin-4; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Models, Biological; Protein Kinase C; Receptors, Antigen, B-Cell; Receptors, Fc; Receptors, IgG; Resting Phase, Cell Cycle; Tetradecanoylphorbol Acetate; Up-Regulation | 1991 |
Topical cyclosporine A inhibits the phorbol ester induced hyperplastic inflammatory response but not protein kinase C activation in mouse epidermis.
Topics: Administration, Topical; Animals; Arachidonic Acid; Arachidonic Acids; Cyclosporine; Cyclosporins; Dermatitis; Dinoprostone; Enzyme Activation; Epidermis; Hyperplasia; Interleukins; Mice; Mice, Hairless; Ornithine Decarboxylase; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transglutaminases | 1989 |
The weak immunosuppressant cyclosporine D as well as the immunologically inactive cyclosporine H are potent inhibitors in vivo of phorbol ester TPA-induced biological effects in mouse skin and of Ca2+/calmodulin dependent EF-2 phosphorylation in vitro.
Topics: Alkaline Phosphatase; Animals; Cyclosporine; Cyclosporins; Cytosol; DNA Replication; Mice; Peptide Elongation Factor 2; Peptide Elongation Factors; Phosphorylation; Protein Biosynthesis; Protein Kinases; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1988 |
Calcineurin is a key signaling enzyme in T lymphocyte activation and the target of the immunosuppressive drugs cyclosporin A and FK506.
Topics: Calcineurin; Calmodulin-Binding Proteins; Cell Line; Cyclosporine; DNA-Binding Proteins; Humans; Lymphocyte Activation; NFATC Transcription Factors; Nuclear Proteins; Phosphoprotein Phosphatases; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 1993 |
Cyclosporin A and FK506 inhibit activation-induced cell death in the murine WEHI-231 B cell line.
Topics: Animals; Apoptosis; Calcium; Cross-Linking Reagents; Cyclosporine; Immunoglobulin M; Immunosuppressive Agents; Ionomycin; Lymphoma, B-Cell; Mice; Polyenes; Receptors, Antigen, B-Cell; Signal Transduction; Sirolimus; Tacrolimus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
FK506 and cyclosporin A each inhibit antigen-specific signaling in the T cell line 171 in the absence of a calcium signal.
Topics: Amino Acid Sequence; Animals; Antigens; Calcineurin; Calcium; Calmodulin-Binding Proteins; Cell Division; Cell Line; Cyclosporine; Cytoplasm; Humans; Interleukin-2; Ionomycin; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Molecular Sequence Data; Muramidase; Phosphoprotein Phosphatases; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate | 1994 |
Properties of transcription factors regulating interleukin-2 gene transcription through the NFAT binding site in untreated or drug-treated naive and memory T-helper cells.
Topics: Animals; Base Sequence; Binding Sites; Cyclosporine; DNA; DNA-Binding Proteins; Female; Gene Expression Regulation; Humans; Interleukin-2; Ionomycin; Molecular Sequence Data; NFATC Transcription Factors; Nuclear Proteins; Oocytes; Promoter Regions, Genetic; Simplexvirus; T-Lymphocytes, Helper-Inducer; Tacrolimus; Tetradecanoylphorbol Acetate; Thymidine Kinase; Transcription Factors; Transcription, Genetic; Xenopus | 1994 |
T cell receptor-induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A.
Topics: Animals; Antigens, Surface; Benzoquinones; CD3 Complex; Cell Survival; Clone Cells; Cyclosporine; fas Receptor; Gene Expression; Genistein; In Vitro Techniques; Ionomycin; Isoflavones; Lactams, Macrocyclic; Mice; Protein-Tyrosine Kinases; Quinones; Receptors, Antigen, T-Cell; Rifabutin; RNA, Messenger; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1994 |
Cyclosporin A blocks induction of tumor necrosis factor-alpha in human B lymphocytes.
Topics: B-Lymphocytes; Cell Line; Cyclosporine; Drug Interactions; Gene Expression; Humans; Interleukin-6; Platelet Activating Factor; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1994 |
Pyrrolidine dithiocarbamate inhibits intercellular adhesion molecule-1 biosynthesis induced by cytokines in human fibroblasts.
Topics: Base Sequence; Cell Line; Cyclosporine; Cytokines; Dexamethasone; DNA; Fibroblasts; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Interleukin-1; Molecular Sequence Data; NF-kappa B; Promoter Regions, Genetic; Pyrrolidines; Recombinant Proteins; RNA, Messenger; Tacrolimus; Tetradecanoylphorbol Acetate; Thiocarbamates | 1995 |
Regulation of L-selectin mRNA in Jurkat cells. Opposing influences of calcium- and protein kinase C-dependent signaling pathways.
Topics: Blotting, Northern; Calcium; Cell Adhesion Molecules; Concanavalin A; Cyclosporine; Flow Cytometry; Gene Expression Regulation; Humans; Ionomycin; L-Selectin; Lymphocyte Activation; Protein Kinase C; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Induction of CD5 on B and T cells is suppressed by cyclosporin A, FK-520 and rapamycin.
Topics: Animals; Antibodies, Anti-Idiotypic; Antigens, CD; Autoimmunity; B-Lymphocytes; Carrier Proteins; CD5 Antigens; Cell Cycle; Cyclosporine; DNA-Binding Proteins; Gene Expression Regulation; Heat-Shock Proteins; Ionomycin; Lymphocyte Activation; Mice; Mice, Inbred CBA; NFATC Transcription Factors; Nuclear Proteins; Polyenes; Sirolimus; T-Lymphocyte Subsets; Tacrolimus; Tacrolimus Binding Proteins; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 1995 |
IL-5 production by CD4+ T cells of asthmatic patients is suppressed by glucocorticoids and the immunosuppressants FK506 and cyclosporin A.
Topics: Adult; Animals; Antigens, Dermatophagoides; Asthma; Base Sequence; Beclomethasone; Calcium; CD4-Positive T-Lymphocytes; Cells, Cultured; Cyclosporine; Dexamethasone; Dose-Response Relationship, Drug; Glucocorticoids; Glycoproteins; Humans; Hypersensitivity, Immediate; Interferon-gamma; Interleukin-2; Interleukin-4; Interleukin-5; Ionomycin; Lymphocyte Activation; Mites; Molecular Sequence Data; Protein Kinase C; Signal Transduction; Tacrolimus; Tetradecanoylphorbol Acetate | 1995 |
Tumor necrosis factor-alpha up-regulates Bcl-2 expression and decreases calcium-dependent apoptosis in human B cell lines.
Topics: Apoptosis; B-Lymphocytes; Calcineurin; Calcium; Calmodulin-Binding Proteins; Cell Line; Cyclosporine; Enzyme Activation; Humans; Phosphoprotein Phosphatases; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation | 1995 |
Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis.
Topics: Animals; Apoptosis; Base Sequence; Cyclosporine; DNA-Binding Proteins; Hybridomas; Immunosuppressive Agents; Interleukin-2; Ionomycin; Ionophores; Lymphocyte Activation; MEF2 Transcription Factors; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Myogenic Regulatory Factors; Nuclear Receptor Subfamily 4, Group A, Member 1; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors | 1995 |
Multiple signals are required for function of the human granulocyte-macrophage colony-stimulating factor gene promoter in T cells.
Topics: Base Sequence; Calcineurin; Calmodulin-Binding Proteins; Cyclosporine; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ionomycin; Leukemia-Lymphoma, Adult T-Cell; Lymphocyte Activation; Molecular Sequence Data; NFATC Transcription Factors; Nuclear Proteins; Phosphoprotein Phosphatases; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Tumor Cells, Cultured | 1995 |
Effects of cyclosporin A, FK 506, and mycalamide A on the activation of murine CD4+ T cells by the murine B7 antigen.
Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; B7-1 Antigen; CD3 Complex; CD4-Positive T-Lymphocytes; Cells, Cultured; CHO Cells; Cricetinae; Cyclosporine; Immunosuppressive Agents; Lymphocyte Activation; Mice; Pyrans; Tacrolimus; Tetradecanoylphorbol Acetate | 1993 |
Comparative in vitro studies on the immunosuppressive effects of purine and pyrimidine synthesis inhibitors.
Topics: Aspartic Acid; Biphenyl Compounds; Calcimycin; Cells, Cultured; Cyclosporine; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Lymphocytes; Mycophenolic Acid; Phosphonoacetic Acid; Ribonucleosides; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Functionally anergic lpr and gld B220+ T cell receptor (TCR)-alpha/beta+ double-negative T cells express CD28 and respond to costimulation with phorbol myristate acetate and antibodies to CD28 and the TCR.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Autoimmune Diseases; CD28 Antigens; CD4 Antigens; CD8 Antigens; Cyclosporine; Enterotoxins; Immune Tolerance; Interleukin-2; Leukocyte Common Antigens; Lymphocyte Activation; Lymphoproliferative Disorders; Mice; Mice, Inbred C3H; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate | 1993 |
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1993 |
Differential modulation of P-glycoprotein transport by protein kinase inhibition.
Topics: Affinity Labels; Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Carrier Proteins; Cyclosporine; Dactinomycin; Dihydropyridines; Drug Resistance; Humans; Isoenzymes; Membrane Glycoproteins; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rhodamine 123; Rhodamines; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 1993 |
Elevation of cytosolic calcium is sufficient to induce growth inhibition in a B cell lymphoma.
Topics: Animals; Antibodies, Anti-Idiotypic; Calcium; Cell Division; Cyclosporine; Cytosol; Immunoglobulin M; Ionomycin; Lipopolysaccharides; Lymphoma, B-Cell; Mice; Mice, Inbred CBA; Tacrolimus; Tetradecanoylphorbol Acetate | 1993 |
IL-1 receptor and TCR signals synergize to activate NF-kappa B-mediated gene transcription.
Topics: Alkaloids; CD3 Complex; Cell Nucleus; Cyclosporine; Cytoplasm; DNA-Binding Proteins; Gene Expression Regulation; Humans; In Vitro Techniques; Interleukin-1; NF-kappa B; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Interleukin-1; RNA, Messenger; Signal Transduction; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 1995 |
Cellular distribution and costimulatory function of rat CD28. Regulated expression during thymocyte maturation and induction of cyclosporin A sensitivity of costimulated T cell responses by phorbol ester.
Topics: Animals; Antibodies, Monoclonal; CD28 Antigens; Cell Differentiation; Cells, Cultured; Cyclosporine; DNA, Complementary; Female; Lymph Nodes; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Inbred Lew; Signal Transduction; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1995 |
Effect of rapamycin on the in vitro release of soluble interleukin-2 receptor by phytohemagglutinin, phorbol myristate acetate, and ionomycin-activated peripheral blood mononuclear cells.
Topics: Cells, Cultured; Cyclosporine; DNA; Humans; Immunosuppressive Agents; Ionomycin; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Polyenes; Receptors, Interleukin-2; Sirolimus; Tetradecanoylphorbol Acetate; Thymidine | 1995 |
Cyclosporin A inhibits CD40 ligand expression in T lymphocytes.
Topics: Adolescent; Adult; Calcineurin; Calmodulin-Binding Proteins; CD40 Ligand; Child; Cyclosporine; Female; Humans; Immunoglobulin Class Switching; Male; Membrane Glycoproteins; Phosphoprotein Phosphatases; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1994 |
The regulation of interleukin 5 and interleukin 3 gene expression in human T cells.
Topics: Base Sequence; Calcimycin; CD4-Positive T-Lymphocytes; Concanavalin A; Cycloheximide; Cyclosporine; DNA Primers; Gene Expression Regulation; Humans; Interleukin-3; Interleukin-5; Lymphocyte Activation; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger; T-Lymphocyte Subsets; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1994 |
What is the dose-response curve for the effects of cyclosporine on calcineurin and cytokine induction in vivo?
Topics: Animals; Calcimycin; Calcineurin; Calmodulin-Binding Proteins; Cells, Cultured; Cyclosporine; Cytokines; Dose-Response Relationship, Drug; Gene Expression; Humans; Interferon-gamma; Interleukin-2; Lymphocytes; Mice; Phosphoprotein Phosphatases; RNA, Messenger; Signal Transduction; Spleen; Tetradecanoylphorbol Acetate | 1994 |
Interleukin-6 and Epstein-Barr virus induction by cyclosporine A: potential role in lymphoproliferative disease.
Topics: Antigens, Viral; B-Lymphocytes; Cell Transformation, Viral; Cells, Cultured; Cyclosporine; Gene Expression Regulation, Viral; Herpesvirus 4, Human; Humans; Immunocompromised Host; Interleukin-6; Ionomycin; Lymphoma, B-Cell; Lymphoproliferative Disorders; Monocytes; Polymerase Chain Reaction; Receptors, Complement 3d; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Virus Infections; Viral Matrix Proteins; Virus Activation | 1994 |
Tepoxalin, a novel immunosuppressive agent with a different mechanism of action from cyclosporin A.
Topics: Base Sequence; Cell Line; Cyclosporine; Humans; Immunosuppressive Agents; Interleukin-2; Ionomycin; Lymphocyte Activation; Molecular Sequence Data; Muromonab-CD3; Polymerase Chain Reaction; Pyrazoles; Receptors, Interleukin-2; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
CD28 signaling causes a sustained down-regulation of I kappa B alpha which can be prevented by the immunosuppressant rapamycin.
Topics: CD28 Antigens; CD4-Positive T-Lymphocytes; Cell Line; Cell Nucleus; Cyclosporine; Cytoplasm; DNA-Binding Proteins; Humans; I-kappa B Proteins; Immunosuppressive Agents; Kinetics; NF-kappa B; NF-KappaB Inhibitor alpha; Polyenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-rel; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Transcription Factors | 1994 |
Cyclosporin A enhances cytokine and phorbol ester-induced fibroblast collagenase expression.
Topics: Blotting, Northern; Calcimycin; Cell Line; Collagenases; Cyclosporine; Cytokines; Dose-Response Relationship, Drug; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Gene Expression Regulation, Enzymologic; Genes, jun; Humans; Interleukin-1; Lung; Phorbol Esters; Proto-Oncogene Proteins c-jun; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Calcium-mediated inhibition of phorbol ester and Tax trans-activation of the human T cell leukaemia virus type 1.
Topics: beta-Galactosidase; Calcium; Cell Line, Transformed; Cyclosporine; Egtazic Acid; Gene Expression Regulation, Viral; Gene Products, tax; Genes, pX; HTLV-I Antigens; Human T-lymphotropic virus 1; Humans; Ionomycin; Repetitive Sequences, Nucleic Acid; Retroviridae Proteins, Oncogenic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1994 |
A role for tyrosine kinase activation in interleukin-1 beta induced nitric oxide production in the insulin producing cell line RINm-5F.
Topics: Alkaloids; Animals; Catechols; Cell Line; Cyclosporine; Enzyme Activation; Genistein; Insulin; Interleukin-1; Isoflavones; Nitric Oxide; Nitriles; Protein-Tyrosine Kinases; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Tyrphostins | 1994 |
Evidence that inhibition of phorbol ester-induced superoxide anion formation by cyclosporin A in phagocytes is not mediated by direct inhibition of protein kinase C.
Topics: Animals; Cell Differentiation; Cells, Cultured; Cyclosporine; Humans; Mice; Neutrophils; Phagocytes; Platelet Aggregation; Protein Kinase C; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles.
Topics: Base Sequence; Binding Sites; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; DNA-Binding Proteins; Gene Expression; Interleukin-2; Kinetics; NF-kappa B; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1994 |
Characterization of a cyclosporin A-sensitive activation pathway in cultured T and natural killer cells.
Topics: Antibodies, Monoclonal; Calcium; Cell Line; Cell Membrane; Cyclosporine; Cytokines; Drug Resistance; GTP-Binding Proteins; Humans; Killer Cells, Natural; Lymphocyte Activation; Pertussis Toxin; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1994 |
Cyclosporin A antagonizes phenylephrine, oxytocin and angiotensin effects on glucose metabolism in rat thymus lymphocytes.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcimycin; Cyclosporine; Dose-Response Relationship, Drug; Fructosediphosphates; Glucose; Glycolysis; Lactates; Lactic Acid; Lymphocytes; Male; Oxytocin; Phenylephrine; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thymus Gland | 1994 |
Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter.
Topics: Animals; Biological Transport; Brain; Carrier Proteins; Cloning, Molecular; Cyclosporine; Cytoplasm; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Golgi Apparatus; Indoles; Kinetics; Maleimides; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oocytes; Organic Anion Transporters; Protein Kinase C; Rats; Serotonin; Subcellular Fractions; Tetradecanoylphorbol Acetate; Xenopus | 1994 |
Mechanisms regulating the mRNA levels of interleukin-5 and two other coordinately expressed lymphokines in the murine T lymphoma EL4.23.
Topics: Animals; Cycloheximide; Cyclosporine; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-10; Interleukin-2; Interleukin-5; Lymphokines; Lymphoma, T-Cell; Mice; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
JNK is involved in signal integration during costimulation of T lymphocytes.
Topics: Animals; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclosporine; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Lymphocyte Activation; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-jun; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1994 |
T-cell activation influences initial DNA synthesis of simian immunodeficiency virus in resting T lymphocytes from macaques.
Topics: Animals; Benzoquinones; CD3 Complex; Cell Division; Cells, Cultured; Cyclosporine; DNA, Viral; Humans; Interleukin-2; Lactams, Macrocyclic; Lymphocyte Activation; Macaca nemestrina; Protein Kinase C; Protein Serine-Threonine Kinases; Quinones; Receptors, Antigen; Rifabutin; Signal Transduction; Simian Immunodeficiency Virus; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1993 |
Regulation of apoptosis in thymocytes.
Topics: Animals; Antigen-Presenting Cells; Apoptosis; Calcimycin; CD3 Complex; Cell Differentiation; Cells, Cultured; Cyclosporine; Female; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1993 |
Production and secretion of interferon-gamma (IFN-gamma) in children with atopic dermatitis.
Topics: Adolescent; Cells, Cultured; Child; Child, Preschool; Cyclosporine; Dermatitis, Atopic; Humans; Infant; Infant, Newborn; Interferon-gamma; Leukocytes, Mononuclear; Tetradecanoylphorbol Acetate | 1994 |
Posttranscriptional regulation of colony-stimulating factor-1 (CSF-1) and CSF-1 receptor gene expression during inhibition of phorbol-ester-induced monocytic differentiation by dexamethasone and cyclosporin A: potential involvement of a destabilizing prot
Topics: Cell Differentiation; Cycloheximide; Cyclosporine; Dexamethasone; Gene Expression Regulation; Humans; Macrophage Colony-Stimulating Factor; Monocytes; Proto-Oncogene Mas; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Irreversible suppression of CD8 expression in CD4-CD8+ thymocytes upon in vitro stimulation.
Topics: Animals; CD8 Antigens; Cyclosporine; Female; Gene Expression Regulation; Immune Tolerance; Immunophenotyping; Interleukin-2; Ionomycin; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Muromonab-CD3; Recombinant Proteins; RNA, Messenger; Signal Transduction; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Thymus Gland | 1993 |
Leflunomide, a novel immunosuppressive agent. The mechanism of inhibition of T cell proliferation.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD28 Antigens; CD3 Complex; Cyclosporine; Humans; Immunosuppressive Agents; In Vitro Techniques; Interleukin-2; Isoxazoles; Leflunomide; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate | 1993 |
Transcriptional and posttranscriptional regulation of the interleukin-4 and interleukin-3 genes in human T cells.
Topics: Blotting, Northern; Concanavalin A; Cycloheximide; Cyclosporine; Gene Expression Regulation; Half-Life; Humans; Interleukin-3; Interleukin-4; Kinetics; Nucleic Acid Hybridization; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1993 |
Expression of PILOT, a putative transcription factor, requires two signals and is cyclosporin A sensitive in T cells.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Calcimycin; Cell Line; Cycloheximide; Cyclosporine; DNA; Drug Synergism; Early Growth Response Protein 3; Escherichia coli; Gene Expression Regulation; Humans; Molecular Sequence Data; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transcription, Genetic; Zinc Fingers | 1993 |
Sex hormones and dexamethasone modulate interleukin-5 gene expression in T lymphocytes.
Topics: Animals; Cell Nucleus; Cycloheximide; Cyclosporine; Dexamethasone; Estradiol; Gene Expression Regulation; Gonadal Steroid Hormones; Hybrid Cells; Interleukin-5; Lymphoma, T-Cell; Mice; Phytohemagglutinins; Progesterone; RNA, Messenger; T-Lymphocytes; Testosterone; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1993 |
Calcium dependent activation of the NF-AT transcription factor by p59fyn.
Topics: Calcimycin; Calcium; Chloramphenicol O-Acetyltransferase; Cyclosporine; DNA-Binding Proteins; Egtazic Acid; Humans; NFATC Transcription Factors; Nuclear Proteins; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1993 |
Glutamate induces a calcineurin-mediated dephosphorylation of Na+,K(+)-ATPase that results in its activation in cerebellar neurons in culture.
Topics: Animals; Calcineurin; Calmodulin-Binding Proteins; Cells, Cultured; Cerebellar Cortex; Cyclosporine; Dizocilpine Maleate; Enzyme Activation; Enzyme Inhibitors; Glutamic Acid; Neurons; Neurotoxins; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Sulfonamides; Tetradecanoylphorbol Acetate | 1996 |
Interleukin-2 receptor (CD25) upregulation on human T-lymphocytes: sensitivity to immunosuppressants is defined by the mode of T-lymphocyte activation.
Topics: Cells, Cultured; Cyclosporine; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Polyenes; Receptors, Interleukin-2; Sirolimus; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1995 |
Raf-1 provides a dominant but not exclusive signal for the induction of CD69 expression on T cells.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Cyclosporine; Dose-Response Relationship, Immunologic; Down-Regulation; Humans; Immunosuppressive Agents; Ionomycin; Ionophores; Lectins, C-Type; Lymphoma; Mitogens; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1995 |
CD40 ligand is expressed and functional on activated neonatal T cells.
Topics: Adult; Antibodies, Monoclonal; Base Sequence; CD3 Complex; CD40 Antigens; CD40 Ligand; Cyclosporine; Dinoprostone; Fetal Blood; Humans; Infant, Newborn; Ionomycin; Ligands; Lymphocyte Activation; Membrane Glycoproteins; Molecular Sequence Data; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Regulation of the nuclear factor of activated T cells in stably transfected Jurkat cell clones.
Topics: Alkaline Phosphatase; Bucladesine; Clone Cells; Colforsin; Cyclosporine; Dinoprostone; DNA-Binding Proteins; Enzyme Inhibitors; Ethers, Cyclic; Female; Humans; Immunosuppressive Agents; Kinetics; Lymphocyte Activation; Marine Toxins; NFATC Transcription Factors; Nuclear Proteins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Placenta; Pregnancy; Protein Phosphatase 1; Recombinant Proteins; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
Increase of intracellular calcium is the essential signal for the expression of CD40 ligand.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Calcium; CD28 Antigens; CD3 Complex; CD40 Ligand; Cell Separation; Cyclosporine; Egtazic Acid; Enzyme Activation; Gene Expression Regulation; Humans; Intracellular Fluid; Ionomycin; Ionophores; Lymphocyte Activation; Membrane Glycoproteins; Mitogens; Protein Kinase C; Receptors, Interleukin-2; Receptors, Transferrin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Nordihydroguaiaretic acid blocks IL-2-independent lymphocyte proliferation and enhances responses to PPD.
Topics: Adjuvants, Immunologic; Bryostatins; Cyclosporine; Humans; Interleukin-2; Interleukin-6; Lactones; Lipoxygenase Inhibitors; Lymphocyte Activation; Macrolides; Masoprocol; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tuberculin | 1996 |
Blocked signal transduction to the ERK and JNK protein kinases in anergic CD4+ T cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; CD28 Antigens; CD3 Complex; Clonal Anergy; Clone Cells; Cyclosporine; DNA-Binding Proteins; Enhancer Elements, Genetic; Enzyme Activation; Interleukin-2; Ionomycin; JNK Mitogen-Activated Protein Kinases; Lymphocyte Activation; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NFATC Transcription Factors; Nuclear Proteins; Protein-Tyrosine Kinases; Signal Transduction; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors | 1996 |
Down-regulation of the protein kinase A pathway by activators of protein kinase C and intracellular Ca2+ in fibroblast cells.
Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium-Transporting ATPases; Chloramphenicol O-Acetyltransferase; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Genes, fos; Genes, jun; Mice; Phosphoprotein Phosphatases; Protein Kinase C; Recombinant Proteins; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factor AP-1; Transcription, Genetic; Transfection | 1996 |
Cyclosporin A and FK506 are potent activators of proopiomelanocortin-derived peptide secretion without affecting corticotrope glucocorticoid receptor function.
Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Corticotropin-Releasing Hormone; Cyclosporine; Dose-Response Relationship, Drug; Gene Expression; Male; Mice; Peptides; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; RNA, Heterogeneous Nuclear; Signal Transduction; Tacrolimus; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
The functional consequences of partial calcineurin inhibition in human peripheral blood mononuclear leucocytes.
Topics: Blotting, Northern; Calcimycin; Calcineurin; Calmodulin-Binding Proteins; Cyclosporine; Humans; Interferon-gamma; Ionomycin; Leukocytes; Muromonab-CD3; Phosphoprotein Phosphatases; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Cyclosporin H is a potent and selective competitive antagonist of human basophil activation by N-formyl-methionyl-leucyl-phenylalanine.
Topics: Basophils; Binding, Competitive; Bryostatins; Chemokine CCL2; Chemokine CCL5; Complement C5a; Cyclosporine; Histamine Release; Humans; Interleukin-1; Interleukin-8; Kinetics; Lactones; Leukotriene C4; Macrolides; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Platelet Activating Factor; Protein Binding; Tetradecanoylphorbol Acetate | 1996 |
Modulation of immune cell proliferation by glycerol monolaurate.
Topics: Animals; B-Lymphocytes; Bacterial Toxins; Cell Membrane; Concanavalin A; Cyclosporine; Enterotoxins; Female; Glycerides; Immunosuppressive Agents; In Vitro Techniques; Interleukin-2; Laurates; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mitogens; Monoglycerides; Signal Transduction; Spleen; Superantigens; Surface-Active Agents; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Anti-CD69 antibodies enhance phorbol-dependent glucose metabolism and Ca2+ levels in human thymocytes. Antagonist effect of cyclosporin A.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; Cyclosporine; Diglycerides; Drug Interactions; Fructosediphosphates; Glucose; Glycolysis; Humans; Immunosuppressive Agents; Lactates; Lactic Acid; Lectins, C-Type; Pyruvates; Pyruvic Acid; Signal Transduction; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thymus Gland; Tritium | 1996 |
Effects of protein kinase C and phosphoprotein phosphatase modulators on Ehrlich cell plasma membrane redox system activity.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Cyclosporine; Enzyme Inhibitors; Ethers, Cyclic; NADH, NADPH Oxidoreductases; Okadaic Acid; Oxidation-Reduction; Phosphoprotein Phosphatases; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Cyclosporin A rescues thymocytes from apoptosis induced by very low concentrations of thapsigargin: effects on mitochondrial function.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antibodies, Blocking; Apoptosis; Calcium; Calcium-Transporting ATPases; Carcinogens; CD3 Complex; Cell Count; Cell Membrane; Cyclosporine; Flow Cytometry; Intracellular Membranes; Membrane Potentials; Mice; Mitochondrial Swelling; Phosphorylation; Tetradecanoylphorbol Acetate; Thapsigargin; Thymus Gland | 1996 |
Dephosphorylation of cofilin in parotid acinar cells.
Topics: Actin Depolymerizing Factors; Amylases; Animals; Calcimycin; Calcium; Carbachol; Cyclic AMP; Cyclosporine; Enzyme Inhibitors; Exocytosis; Ionophores; Isoproterenol; Marine Toxins; Microfilament Proteins; Nerve Tissue Proteins; Oxazoles; Parotid Gland; Phosphoprotein Phosphatases; Phosphorylation; Rats; Tacrolimus; Tetradecanoylphorbol Acetate | 1996 |
Cyclosporin A inhibits prostaglandin E2 production by fetal amnion cells in response to various stimuli.
Topics: Amnion; Cells, Cultured; Cyclosporine; Dinoprostone; Female; Humans; Immunosuppressive Agents; In Vitro Techniques; Interleukin-1; Ionomycin; Pregnancy; Tetradecanoylphorbol Acetate | 1996 |
Calcium-dependent immediate-early gene induction in lymphocytes is negatively regulated by p21Ha-ras.
Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclosporine; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Gene Expression; Genes, Immediate-Early; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Immediate-Early Proteins; Ionomycin; Lymphocyte Activation; Models, Biological; Protein Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins p21(ras); T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
Developmental control of antigen-induced thymic transcription factors.
Topics: Animals; Cyclosporine; DNA; DNA-Binding Proteins; Gene Expression Regulation, Developmental; H-2 Antigens; Immunophenotyping; Ionomycin; Mice; Mice, Inbred CBA; Mice, Transgenic; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Protein Binding; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Thymus Gland; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic | 1996 |
Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death.
Topics: Adenovirus E1B Proteins; Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Cell Cycle; Cell Line; Cell Survival; Cycloheximide; Cyclosporine; Dexamethasone; Gamma Rays; Humans; Interleukin-3; Jurkat Cells; Kinetics; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Redox regulation of the mitogen-activated protein kinase pathway during lymphocyte activation.
Topics: Alkaloids; Antioxidants; Benzophenanthridines; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cyclosporine; Cysteamine; DNA-Binding Proteins; Humans; Interphase; Ionomycin; Jurkat Cells; Lymphocyte Activation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocytes; Phenanthridines; Reactive Oxygen Species; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 1997 |
Suppressive effects of Ganoderma lucidum on proliferation of peripheral blood mononuclear cells.
Topics: Basidiomycota; Cyclosporine; Humans; Immunosuppressive Agents; In Vitro Techniques; Ionomycin; Lymphocyte Activation; Molecular Weight; Phytohemagglutinins; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1997 |
Modulation of endoplasmic reticulum calcium pump expression during T lymphocyte activation.
Topics: Calcium-Transporting ATPases; Cell Line; Cyclosporine; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; Humans; Ionomycin; Isoenzymes; Jurkat Cells; Lymphocyte Activation; Sarcoplasmic Reticulum; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Cyclosporin A-sensitive calcium signaling represses NFkappaB activation in human bronchial epithelial cells and enhances NFkappaB activation in Jurkat T-cells.
Topics: Base Sequence; Bronchi; Calcium; Cell Line, Transformed; Cyclosporine; Epithelium; Genes, Reporter; Humans; Inflammation; Ionomycin; Jurkat Cells; Luciferases; NF-kappa B; Oligonucleotide Probes; Signal Transduction; Tacrolimus; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection | 1997 |
Csa-19, a radiation-responsive human gene, identified by an unbiased two-gel cDNA library screening method in human cancer cells.
Topics: Age Factors; Blotting, Northern; Breast Neoplasms; Cloning, Molecular; Colforsin; Cyclosporine; DNA, Complementary; Dose-Response Relationship, Radiation; Down-Regulation; Gene Expression Regulation, Developmental; Gene Library; Genes, p53; HL-60 Cells; Humans; Molecular Sequence Data; Neutrons; Oncogenes; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured; X-Rays | 1997 |
Triple synergism of human T-lymphotropic virus type 1-encoded tax, GATA-binding protein, and AP-1 is required for constitutive expression of the interleukin-5 gene in adult T-cell leukemia cells.
Topics: Calcimycin; Cyclosporine; DNA-Binding Proteins; GATA4 Transcription Factor; Gene Expression Regulation, Viral; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Immunosuppressive Agents; Interleukin-5; Ionophores; Leukemia, T-Cell; Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1997 |
GABP factors bind to a distal interleukin 2 (IL-2) enhancer and contribute to c-Raf-mediated increase in IL-2 induction.
Topics: Cloning, Molecular; Cyclosporine; DNA; DNA-Binding Proteins; Enhancer Elements, Genetic; GA-Binding Protein Transcription Factor; Gene Expression Regulation; Humans; Interleukin-2; Ionomycin; Ionophores; Jurkat Cells; Point Mutation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors | 1997 |
Effect of topically applied cyclosporin A on arachidonic acid (AA)- and tetradecanoylphorbol acetate (TPA)-induced dermal inflammation in mouse ear.
Topics: Acetylglucosaminidase; Administration, Topical; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Capillary Permeability; Cyclooxygenase Inhibitors; Cyclosporine; Dermatitis, Contact; Dexamethasone; Eicosanoids; Glucocorticoids; Immunosuppressive Agents; Indomethacin; Lipoxygenase Inhibitors; Male; Mice; Peroxidase; Pyrazoles; Tetradecanoylphorbol Acetate | 1997 |
Cyclosporine-insensitive partial signaling and multiple roles of Ca2+ in Fas ligand-induced lysis.
Topics: Animals; Calcium; CD2 Antigens; Cell Line; Cyclosporine; Cytotoxicity, Immunologic; Down-Regulation; Fas Ligand Protein; fas Receptor; Immunosuppressive Agents; Ionomycin; Ligands; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred MRL lpr; RNA, Messenger; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1997 |
T cell receptor signals enhance susceptibility to Fas-mediated apoptosis.
Topics: Animals; Apoptosis; Calcium; Cyclosporine; Dactinomycin; DNA-Binding Proteins; Drug Synergism; Enzyme Activation; Fas Ligand Protein; fas Receptor; Hybridomas; Immunosuppressive Agents; Ionomycin; Ionophores; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Nuclear Receptor Subfamily 4, Group A, Member 1; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 1997 |
Cyclolinopeptide A (CLA) mediates its immunosuppressive activity through cyclophilin-dependent calcineurin inactivation.
Topics: Amino Acid Sequence; Animals; Calcineurin Inhibitors; Cells, Cultured; Cyclosporine; Immunosuppressive Agents; Kinetics; Lymphocyte Activation; Lymphocytes; Molecular Sequence Data; Peptides; Peptides, Cyclic; Peptidylprolyl Isomerase; Phosphorylation; Polyenes; Sirolimus; Swine; Tetradecanoylphorbol Acetate | 1997 |
P-glycoprotein-mediated multidrug resistance is modulated by pretreatment with chemosensitizers in HCT-8 carcinoma cells in vitro.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Cyclosporins; Doxorubicin; Drug Resistance, Multiple; Epithelial Cells; Humans; Ileal Neoplasms; Ileocecal Valve; Kinetics; Phosphorylation; Rhodamine 123; Rhodamines; Tamoxifen; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Verapamil; Vinblastine | 1998 |
T lymphocyte activation signals for interleukin-2 production involve activation of MKK6-p38 and MKK7-SAPK/JNK signaling pathways sensitive to cyclosporin A.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cyclosporine; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Interleukin-2; Jurkat Cells; Lymphocyte Activation; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1998 |
CD38 is functionally dependent on the TCR/CD3 complex in human T cells.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation; Apoptosis; Calcium; CD28 Antigens; Cell Division; Clone Cells; Cyclosporine; fas Receptor; Genetic Variation; Humans; Isoenzymes; Jurkat Cells; Kinetics; Membrane Glycoproteins; NAD+ Nucleosidase; Phospholipase C gamma; Phosphorylation; Receptor-CD3 Complex, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Effects of repeated cyclosporin A administration on iminodipropionitrile-induced dyskinesia and TRE-/CRE-binding activities in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cell Nucleus; Corpus Striatum; Cyclic AMP; Cyclosporine; Dopamine; Drug Administration Schedule; Dyskinesia, Drug-Induced; Frontal Lobe; Hippocampus; Homovanillic Acid; Male; Motor Activity; Nitriles; Nucleus Accumbens; Organ Specificity; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; RNA, Messenger; Tetradecanoylphorbol Acetate; Up-Regulation | 1998 |
Uncoupling of Ca2+ transport ATPase in muscle and blood platelets by diacylglycerol analogues and cyclosporin A antagonism.
Topics: Adenosine Triphosphate; Animals; Blood Platelets; Calcium; Calcium-Transporting ATPases; Cyclosporine; Diglycerides; Humans; In Vitro Techniques; Muscle, Skeletal; Phosphorylation; Rabbits; Sarcoplasmic Reticulum; Tacrolimus; Tetradecanoylphorbol Acetate; Uncoupling Agents | 1997 |
PMA/ionomycin induces Ig kappa 3' enhancer activity which is in part mediated by a unique NFAT transcription complex.
Topics: Animals; B-Lymphocytes; Cell Line; Cyclosporine; DNA-Binding Proteins; Drug Synergism; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; Immunoglobulin kappa-Chains; Ionomycin; Mice; Mice, Inbred C57BL; Mice, Transgenic; NFATC Transcription Factors; Nuclear Proteins; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Up-Regulation | 1998 |
Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway.
Topics: Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; CD28 Antigens; CD3 Complex; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Imidazoles; Interleukin-2; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Lymphocyte Activation; MAP Kinase Kinase 1; MAP Kinase Kinase 7; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transgenes | 1998 |
Effects of steroid hormones and cyclosporine A on taurine-transporter activity in the RAW264.7 cell line.
Topics: Animals; Cell Line, Transformed; Cyclosporine; Glucocorticoids; Ionomycin; Ionophores; Mice; Mitogens; Pregnanes; Taurine; Tetradecanoylphorbol Acetate | 1998 |
Simultaneous cross-linking of CD6 and CD28 induces cell proliferation in resting T cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Antibodies, Monoclonal; Antigens, CD; Carcinogens; CD28 Antigens; CD3 Complex; Cell Division; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Indoles; Interleukin-2; Lymphocyte Activation; Maleimides; Protein Kinase C; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1998 |
ETA receptor mediated inhibition of intracellular pH regulation in cultured bovine corneal epithelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chelating Agents; Cyclosporine; Diuretics; Egtazic Acid; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epithelium, Corneal; Hydrogen-Ion Concentration; Immunosuppressive Agents; Intracellular Fluid; Naphthalenes; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Kinase C; Receptors, Endothelin; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1998 |
Inhibition of CD28/CD3-mediated costimulation of naive and memory human T lymphocytes by intracellular incorporation of polyclonal antibodies specific for the activator protein-1 transcriptional complex.
Topics: Antibodies; Antibody Specificity; CD28 Antigens; CD3 Complex; Cell Adhesion; Cell Separation; Cyclosporine; Humans; Immunologic Memory; Immunosuppressive Agents; Interleukin-2; Interphase; Intracellular Fluid; Ionomycin; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic | 1998 |
The cyclosporin A-sensitive nuclear factor of activated T cells (NFAT) proteins are expressed in vascular smooth muscle cells. Differential localization of NFAT isoforms and induction of NFAT-mediated transcription by phospholipase C-coupled cell surface
Topics: Angiotensin II; Animals; Becaplermin; Calcium; Cells, Cultured; Colforsin; Cyclosporine; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; GTP-Binding Proteins; Immunohistochemistry; Muscle, Smooth, Vascular; NFATC Transcription Factors; Nuclear Proteins; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thrombin; Transcription Factors; Type C Phospholipases | 1998 |
A regulatory element in the CD95 (APO-1/Fas) ligand promoter is essential for responsiveness to TCR-mediated activation.
Topics: Apoptosis; Base Sequence; Binding Sites; Cyclosporine; DNA; DNA-Binding Proteins; Fas Ligand Protein; fas Receptor; Gene Expression Regulation; Genes, Regulator; Humans; Ionomycin; Jurkat Cells; Ligands; Lymphocyte Activation; Membrane Glycoproteins; NFATC Transcription Factors; Nuclear Proteins; Promoter Regions, Genetic; Receptors, Antigen, T-Cell; Sp1 Transcription Factor; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 1998 |
Flow cytometric detection of IL-6 production by CD14+ cells: the effect of in vitro addition of cyclosporine-A and prednisolone.
Topics: Cell Differentiation; Cells, Cultured; Cyclosporine; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; In Vitro Techniques; Interleukin-6; Lipopolysaccharide Receptors; Lipopolysaccharides; Lymphocytes; Prednisolone; Sensitivity and Specificity; Tetradecanoylphorbol Acetate | 1998 |
Flow cytometry detection of intracytoplasmic cytokines after Neoral or sirolimus intake is an informative tool for monitoring in vivo immunosuppressive efficacy in renal transplant recipients.
Topics: Cells, Cultured; Cyclosporine; Cytokines; Drug Monitoring; Flow Cytometry; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Ionomycin; Kidney Transplantation; Kinetics; Monitoring, Immunologic; Polyenes; Reference Values; Sirolimus; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells; Time Factors | 1998 |
Curcumin blocks cyclosporine A-resistant CD28 costimulatory pathway of human T-cell proliferation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinogens; CD28 Antigens; Cell Division; Cells, Cultured; Curcumin; Cyclosporine; Humans; Immunosuppressive Agents; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1998 |
Cyclosporin A inhibits 12-O-tetradecanoyl-phorbol-13-acetate-induced cutaneous inflammation in severe combined immunodeficient mice that lack functional lymphocytes.
Topics: Animals; Cyclosporine; Dermatitis, Contact; Epidermis; Immune Tolerance; Immunosuppressive Agents; Lymphocytes; Mice; Mice, SCID; Tetradecanoylphorbol Acetate | 1998 |
Lymphotactin: a key regulator of lymphocyte trafficking during acute graft rejection.
Topics: Acute Disease; Animals; Blotting, Northern; Cells, Cultured; Chemotaxis, Leukocyte; Cyclosporine; Gene Expression; Graft Rejection; Immunosuppressive Agents; In Situ Hybridization; Kidney Transplantation; Lymphocytes; Lymphokines; Male; Phytohemagglutinins; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sialoglycoproteins; Tacrolimus; Tetradecanoylphorbol Acetate; Transplantation, Homologous | 1998 |
HIV/gp120 and PMA/ionomycin induced apoptosis but not activation induced cell death require PKC for Fas-L upregulation.
Topics: Antigens, Surface; Apoptosis; Cell Death; Clone Cells; Cyclosporine; Enzyme Inhibitors; Fas Ligand Protein; Gene Expression Regulation; HIV Envelope Protein gp120; Humans; Ionomycin; Kinetics; Lymphocyte Activation; Membrane Glycoproteins; Naphthalenes; Protein Kinase C; Receptors, Antigen, T-Cell; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Th1 Cells | 1998 |
Analysis of heat shock-induced monophosphorylation of stathmin in human T lymphoblastic cell line JURKAT by two-dimensional gel electrophoresis.
Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP; Cyclosporine; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Hot Temperature; Humans; Isoelectric Point; Jurkat Cells; Microtubule Proteins; Molecular Sequence Data; Molecular Weight; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Stathmin; Staurosporine; Tetradecanoylphorbol Acetate | 1998 |
Calmodulin dependence of NFkappaB activation.
Topics: Animals; Calmodulin; Cyclosporine; Genes, Reporter; Humans; Ionomycin; Jurkat Cells; Kinetics; Luciferases; Mice; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins; Recombinant Proteins; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor RelB; Transcription Factors; Transfection | 1998 |
Modulation of excision repair cross complementation group 1 (ERCC-1) mRNA expression by pharmacological agents in human ovarian carcinoma cells.
Topics: Benzoquinones; Cisplatin; Cyclosporine; DNA Repair; DNA-Binding Proteins; Endonucleases; Gene Expression Regulation; Humans; Lactams, Macrocyclic; Protein Biosynthesis; Proteins; Quinones; Rifabutin; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Plant alkaloid tetrandrine downregulates protein kinase C-dependent signaling pathway in T cells.
Topics: Alkaloids; Antigens; Antineoplastic Agents, Phytogenic; Benzylisoquinolines; Calcium Channel Blockers; Cell Division; Cyclosporine; DNA Fragmentation; Down-Regulation; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Humans; Immunosuppressive Agents; In Vitro Techniques; Interleukin-2; Ionomycin; Protein Kinase C; Receptors, Interleukin-2; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1999 |
Abnormal functional behavior of peripheral blood mononuclear cells from Hashimoto's disease patients. Immunomodulatory effects of cyclosporin A.
Topics: Adjuvants, Immunologic; Adult; Antibodies, Monoclonal; CD3 Complex; Cell Division; Cells, Cultured; Cyclosporine; Dansyl Compounds; Female; Humans; Interferon-alpha; Interleukin-10; Interleukin-13; Interleukin-2; Interleukin-4; Leukocytes, Mononuclear; Mitogens; Receptors, Very Late Antigen; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thyroiditis, Autoimmune | 1999 |
Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation.
Topics: Binding Sites; Bronchi; Cyclosporine; Diterpenes; Enhancer Elements, Genetic; Epithelial Cells; Epoxy Compounds; Gene Expression Regulation; Humans; Immunosuppressive Agents; Interleukin-2; Interleukin-8; Jurkat Cells; Lymphocyte Activation; NF-kappa B; Phenanthrenes; Purines; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1999 |
The human prolactin gene upstream promoter is regulated in lymphoid cells by activators of T-cells and by cAMP.
Topics: Base Sequence; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; DNA Primers; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; Isoquinolines; Jurkat Cells; Lymphocyte Activation; Phosphoprotein Phosphatases; Phytohemagglutinins; Prolactin; Promoter Regions, Genetic; Protein Binding; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 1999 |
IL-2-independent activation and proliferation in human T cells induced by CD28.
Topics: Animals; Antibodies, Blocking; B7-1 Antigen; CD28 Antigens; Cell Division; CHO Cells; Cricetinae; Cyclosporine; Cytokines; DNA-Binding Proteins; Drug Resistance; Drug Synergism; Growth Inhibitors; Humans; Interleukin-2; Interphase; Lymphocyte Activation; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Promoter Regions, Genetic; Receptors, Interleukin-2; Signal Transduction; Solubility; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation | 1999 |
Endothelin-1 induces expression of fetal genes through the interleukin-6 family of cytokines in cardiac myocytes.
Topics: Animals; Animals, Newborn; Antigens, CD; Atrial Natriuretic Factor; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclosporine; Cytokine Receptor gp130; Cytokines; Egtazic Acid; Endothelin-1; Gene Expression Regulation, Developmental; Growth Inhibitors; Heart; Interleukin-6; Ionomycin; Ionophores; Leukemia Inhibitory Factor; Lymphokines; Membrane Glycoproteins; Mutation; Myocardium; Myosin Heavy Chains; Natriuretic Peptide, Brain; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate | 1999 |
Regulatory effects of cytokines and cyclosporine A on peripheral blood mononuclear cells from stable multiple sclerosis patients.
Topics: Adult; Cyclosporine; Cytokines; Female; Humans; Immunosuppressive Agents; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; Multiple Sclerosis; Phytohemagglutinins; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate | 1999 |
Caerulein-induced NF-kappaB/Rel activation requires both Ca2+ and protein kinase C as messengers.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Ceruletide; Chelating Agents; Cyclosporine; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Gastrointestinal Agents; In Vitro Techniques; Male; NF-kappa B; Pancreas; Protein Kinase C; Proto-Oncogene Proteins; Rats; Rats, Wistar; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription Factor RelB; Transcription Factors | 1999 |
Cyclosporin A inhibits Ca2+-mediated upregulation of the DNA repair enzyme DNA polymerase beta in human peripheral blood mononuclear cells.
Topics: Animals; Base Sequence; Calcineurin; Calcium; Cyclosporine; DNA Polymerase beta; DNA Primers; DNA Repair; Humans; Immunosuppressive Agents; In Vitro Techniques; Ionomycin; Ionophores; Leukocytes, Mononuclear; Neoplasms; RNA, Messenger; Tacrolimus; Tetradecanoylphorbol Acetate; Up-Regulation | 1999 |
Opposing effects of rapamycin and cyclosporin A on activation-induced Ca(2+) release.
Topics: Animals; Calcium; Cell Division; Cell Line; Chelating Agents; Concanavalin A; Cyclosporine; Dose-Response Relationship, Drug; Egtazic Acid; Humans; Immunosuppressive Agents; Ionomycin; Kinetics; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocytes; Sirolimus; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
A human T-cell line with inducible production of interleukins 5 and 4. A model for studies of gene expression.
Topics: Base Sequence; Cyclosporine; Dexamethasone; DNA Primers; Gene Expression; Humans; Interleukin-4; Interleukin-5; Jurkat Cells; Leukemia, T-Cell; Models, Biological; RNA, Messenger; RNA, Neoplasm; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured | 1999 |
Plant alkaloid tetrandrine and its analog block CD28-costimulated activities of human peripheral blood T cells: potential immunosuppressants in transplantation immunology.
Topics: Alkaloids; Benzylisoquinolines; CD28 Antigens; Cyclosporine; Cytokines; Humans; Immunosuppressive Agents; Isoquinolines; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tetrahydroisoquinolines | 1999 |
Different effects of cyclosporine and tacrolimus on the activation of mesangial metalloproteinases and their inhibitors.
Topics: Cells, Cultured; Cyclosporine; Enzyme Activation; Glomerular Mesangium; Humans; Kidney; Kinetics; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Tacrolimus; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Tumor Necrosis Factor-alpha | 1999 |
T cell activation up-regulates the expression of the focal adhesion kinase Pyk2: opposing roles for the activation of protein kinase C and the increase in intracellular Ca2+.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; CD28 Antigens; Cell Adhesion Molecules; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Humans; Intracellular Fluid; Ionophores; Jurkat Cells; Lymphocyte Activation; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic; Up-Regulation | 1999 |
High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cell Separation; Cells, Cultured; Cyclosporine; Humans; Interleukin-15; Interleukin-17; Interleukin-2; Ionomycin; Leukocytes, Mononuclear; Methylprednisolone; Middle Aged; Osteoarthritis; Phytohemagglutinins; Synovial Fluid; Tetradecanoylphorbol Acetate | 2000 |
Cyclosporin A decreases human macrophage interleukin-6 synthesis at post-transcriptional level.
Topics: Cell Differentiation; Cell Division; Cell Survival; Cycloheximide; Cyclosporine; Dimethyl Sulfoxide; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-6; Macrophages; Protein Biosynthesis; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; U937 Cells | 1999 |
Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant.
Topics: Calcium Channel Blockers; Calcium Channels; Clotrimazole; Cyclosporine; Cytochrome P-450 Enzyme System; Drug Design; Drug Interactions; Electric Conductivity; Humans; Immunosuppressive Agents; Intermediate-Conductance Calcium-Activated Potassium Channels; Ion Channel Gating; Ionomycin; Lymphocyte Activation; Potassium Channels; Pyrazoles; Structure-Activity Relationship; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2000 |
NFAT-controlled expression of GFP permits visualization and isolation of antigen-stimulated primary human T cells.
Topics: Antigens; Binding Sites; Cell Separation; Cells, Cultured; Cyclosporine; DNA-Binding Proteins; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Immunosuppressive Agents; Ionomycin; Luminescent Proteins; Lymphocyte Activation; NFATC Transcription Factors; Nuclear Proteins; Receptors, Antigen, T-Cell; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 2000 |
Requirement for integration of phorbol 12-myristate 13-acetate and calcium pathways is preserved in the transactivation domain of NFAT1.
Topics: Calcineurin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calcium-Calmodulin-Dependent Protein Kinases; Cyclosporine; DNA-Binding Proteins; Humans; Jurkat Cells; NFATC Transcription Factors; Nuclear Proteins; Structure-Activity Relationship; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation | 2000 |
Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation.
Topics: Administration, Topical; Animals; Arginine; Biological Transport; Biotinylation; Cyclosporine; Cyclosporins; Humans; Inflammation; Interleukin-2; Ionomycin; Jurkat Cells; Mice; Mice, Inbred BALB C; Molecular Structure; Prodrugs; Skin; Skin Absorption; Tetradecanoylphorbol Acetate | 2000 |
Specific induction of RGS16 (regulator of G-protein signalling 16) mRNA by protein kinase C in CEM leukaemia cells is mediated via tumour necrosis factor alpha in a calcium-sensitive manner.
Topics: Androstadienes; Bucladesine; Calcimycin; Calcineurin; Calcium; Calcium Signaling; Cyclosporine; DNA-Binding Proteins; Egtazic Acid; Enzyme Activation; Humans; Kinetics; Mitogen-Activated Protein Kinases; NFATC Transcription Factors; Nuclear Proteins; Protein Kinase C; Proteins; RGS Proteins; RNA, Messenger; Tacrolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin | 2000 |
Effect of cyclosporin A on inflammatory cytokine production by U937 monocyte-like cells.
Topics: Cell Differentiation; Cell Division; Cell Survival; Cyclosporine; Cytokines; Dimethyl Sulfoxide; Humans; Immunosuppressive Agents; Inflammation Mediators; Interleukin-1; Interleukin-6; Interleukin-8; Monocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells | 2000 |
Regulation of the IL-10 production by human T cells.
Topics: Antibodies, Monoclonal; B7-1 Antigen; Calcineurin; Calcium Signaling; CD4-Positive T-Lymphocytes; CD58 Antigens; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; Dinoprostone; DNA-Binding Proteins; Gene Expression Regulation; Humans; Immunosuppressive Agents; Interferon Type I; Interleukin-10; Interleukin-12; Interleukin-2; Ionomycin; Ionophores; Leukocyte Common Antigens; Lymphocyte Activation; NFATC Transcription Factors; Nuclear Proteins; Protein Kinase C; Recombinant Proteins; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Transcription Factors | 2001 |
Sp1-p53 heterocomplex mediates activation of HTLV-I long terminal repeat by 12-O-tetradecanoylphorbol-13-acetate that is antagonized by protein kinase C.
Topics: Base Sequence; Blotting, Western; Cell Line; Consensus Sequence; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclosporine; DNA; Gene Expression Regulation, Viral; Human T-lymphotropic virus 1; Humans; Indoles; Jurkat Cells; Macromolecular Substances; Maleimides; Mutation; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Response Elements; Sp1 Transcription Factor; Terminal Repeat Sequences; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Suppressor Protein p53 | 2001 |
Effect of kanglemycin C on lymphocyte proliferation induced by tetradecanoylphorbol acetate and ionomycin.
Topics: Animals; Calcineurin; Cell Division; Cyclosporine; Female; Immunosuppressive Agents; Ionomycin; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Rifamycins; Spleen; Tetradecanoylphorbol Acetate | 2000 |
Targeted inhibition of calcineurin signaling blocks calcium-dependent reactivation of Kaposi sarcoma-associated herpesvirus.
Topics: Calcineurin; Calcineurin Inhibitors; Calcium Signaling; Capsid; Cells, Cultured; Cyclosporine; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; Herpesvirus 8, Human; Humans; Indoles; Ionomycin; Maleimides; Microscopy, Electron; NFATC Transcription Factors; Nuclear Proteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factors; Transcription, Genetic; Transfection; Viral Proteins; Virus Activation | 2001 |
Regulation of nuclear factor of activated T cells by phosphotyrosyl-specific phosphatase activity: a positive effect on HIV-1 long terminal repeat-driven transcription and a possible implication of SHP-1.
Topics: Active Transport, Cell Nucleus; Adult; Cyclosporine; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation; HIV Long Terminal Repeat; HIV-1; Humans; Immunosuppressive Agents; Interleukin-1; Interleukin-2; Intracellular Signaling Peptides and Proteins; Ionomycin; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Organometallic Compounds; Phytohemagglutinins; Promoter Regions, Genetic; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Recombinant Fusion Proteins; Recombinant Proteins; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; ZAP-70 Protein-Tyrosine Kinase | 2001 |
Differential regulation of CD3- and CD28-induced IL-2 and IFN-gamma production by a novel tyrosine kinase inhibitor XR774 from Cladosporium cf. cladosporioides.
Topics: Benzoquinones; CD28 Antigens; CD3 Complex; Cladosporium; Cyclosporine; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fluorenes; Humans; Interferon-gamma; Interleukin-2; Ionomycin; Jurkat Cells; Lactams, Macrocyclic; Protein-Tyrosine Kinases; Quinones; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2001 |
Tachykinin activation of human monocytes from patients with rheumatoid arthritis: in vitro and ex-vivo effects of cyclosporin A.
Topics: Arthritis, Rheumatoid; Carcinogens; Cells, Cultured; Cyclosporine; Humans; Immunosuppressive Agents; In Vitro Techniques; Monocytes; Neurokinin A; Peptide Fragments; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Respiratory Burst; Substance P; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro.
Topics: Aniline Compounds; Animals; Blood; Calcium; CD28 Antigens; Concanavalin A; Crotonates; Cyclosporine; Flow Cytometry; Hydroxybutyrates; Immunosuppressive Agents; Ionomycin; Kinetics; Lymphocyte Activation; Male; Mitogens; Nitriles; Rats; Rats, Inbred Lew; Sirolimus; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Toluidines | 2001 |
Inhibition of neutrophil responses by cyclosporin A. An insight into molecular mechanisms.
Topics: Binding, Competitive; Calcium; Caseins; Cell Degranulation; Cell Survival; Chemotaxis; Cyclosporine; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Peptide; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
Caspase-mediated calcineurin activation contributes to IL-2 release during T cell activation.
Topics: Aspartic Acid; Calcineurin; Calcineurin Inhibitors; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cyclosporine; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Humans; Interleukin-2; Ionomycin; Ionophores; Jurkat Cells; Lymphocyte Activation; NFATC Transcription Factors; Nuclear Proteins; Phosphorylation; Phytohemagglutinins; Proteins; Spectrin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; X-Linked Inhibitor of Apoptosis Protein | 2001 |
Nuclear factor-kappaB as a target of cyclosporin in acute hypovolemic hemorrhagic shock.
Topics: Animals; Aorta; Blotting, Western; Cells, Cultured; Cyclosporine; Cytoplasm; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Hydrogen Peroxide; I-kappa B Proteins; Immunosuppressive Agents; In Vitro Techniques; Liver; Macrophage Activation; Macrophages, Peritoneal; Male; Models, Animal; NF-kappa B; NF-KappaB Inhibitor alpha; Phenylephrine; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Shock; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents | 2001 |
Effects of cyclosporine and hydrocortisone on Kaposi's sarcoma-associated herpesvirus genome replication and cell apoptosis induction.
Topics: Apoptosis; Cyclosporine; DNA Replication; Herpesvirus 8, Human; Humans; Hydrocortisone; Immunosuppressive Agents; Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Viral Proteins; Virus Replication | 2001 |
P-gp-induced modulation of regulatory volume increase occurs via PKC in mouse proximal tubule.
Topics: Actin Cytoskeleton; Androstadienes; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Carcinogens; Chromones; Colchicine; Cyclosporine; Cytochalasin B; Diuretics, Osmotic; Enzyme Inhibitors; Hypertonic Solutions; Kidney Tubules, Proximal; Male; Mannitol; Mice; Mice, Knockout; Microtubules; Morpholines; Naphthalenes; Phorbols; Phosphatidylinositol 3-Kinases; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Wortmannin | 2002 |
Regulation of activation-induced receptor activator of NF-kappaB ligand (RANKL) expression in T cells.
Topics: Animals; Anti-Bacterial Agents; Calcitriol; Calcium Signaling; Carrier Proteins; CD3 Complex; Cell Differentiation; Cell Line; Cyclosporine; Depsipeptides; Dexamethasone; Fas Ligand Protein; Gallic Acid; Gene Expression Regulation; Hybridomas; Lymphocyte Activation; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NF-kappa B; Osteoclasts; Peptides, Cyclic; Proto-Oncogene Proteins c-myc; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Antigen, T-Cell; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 2002 |
Localization of calcineurin/NFAT in human skin and psoriasis and inhibition of calcineurin/NFAT activation in human keratinocytes by cyclosporin A.
Topics: Biological Transport; Calcineurin; Calcineurin Inhibitors; Carcinogens; Cell Differentiation; Cell Membrane; Cell Nucleus; Cells, Cultured; Cyclophilin A; Cyclosporine; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Humans; Immunosuppressive Agents; Ionomycin; Ionophores; Keratinocytes; NFATC Transcription Factors; Nuclear Proteins; Psoriasis; Signal Transduction; Skin; Tacrolimus; Tacrolimus Binding Protein 1A; Tetradecanoylphorbol Acetate; Transcription Factors | 2002 |
A tactic for screening inhibitors of interleukin-2 production.
Topics: Animals; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Formazans; Interleukin-2; Mice; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thymoma; Time Factors; Tumor Cells, Cultured | 2002 |
Mutational analyses of the signals involved in the subcellular location of DSCR1.
Topics: Amino Acid Motifs; Animals; Calcineurin; Calcineurin Inhibitors; Cell Line; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cyclosporine; DNA-Binding Proteins; Down Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Kidney; Muscle Proteins; Mutagenesis, Site-Directed; Nuclear Proteins; Point Mutation; Proline; Protein Isoforms; Protein Sorting Signals; Serine; src Homology Domains; Tetradecanoylphorbol Acetate; Threonine | 2002 |
Activation of channel catfish (Ictalurus punctatus) T cells involves NFAT-like transcription factors.
Topics: Animals; Blotting, Western; Calcimycin; Concanavalin A; Cyclosporine; DNA-Binding Proteins; Ictaluridae; Immunosuppressive Agents; Lipopolysaccharides; Lymphocyte Activation; NFATC Transcription Factors; Nuclear Proteins; Phosphoric Monoester Hydrolases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine; Transcription Factors | 2002 |
In vitro effects of ginkgolide B combined with cyclosporin A on T-lymphocyte activation and IL-5 expression in peripheral blood mononuclear cells from asthmatic subjects.
Topics: Adult; Asthma; Cells, Cultured; Cyclosporine; Cytokines; Diterpenes; Female; Flow Cytometry; Ginkgolides; Humans; In Vitro Techniques; Interleukin-5; Kuwait; Lactones; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Phytotherapy; Platelet Activating Factor; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2002 |
Flow cytometric detection of intracellular IL-12 release: in vitro effect of widely used immunosuppressants.
Topics: Cyclosporine; Dexamethasone; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-12; Interleukin-15; Leukocytes, Mononuclear; Lipopolysaccharides; Sirolimus; Tetradecanoylphorbol Acetate | 2002 |
NFAT transcription factors are critical survival factors that inhibit cardiomyocyte apoptosis during phenylephrine stimulation in vitro.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Apoptosis; Calcineurin; Calcineurin Inhibitors; Cell Survival; Cyclosporine; DNA-Binding Proteins; Gene Expression; Green Fluorescent Proteins; Humans; In Situ Nick-End Labeling; Ionomycin; Jurkat Cells; Luminescent Proteins; Molecular Sequence Data; Myocytes, Cardiac; NFATC Transcription Factors; Nuclear Proteins; Oligopeptides; Phenylephrine; Protein Isoforms; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 2003 |
Atypical mechanisms regulate the PMA-induced expression of IFN-gamma in a porcine trophectoderm cell line.
Topics: Animals; Calcimycin; Cell Polarity; Cyclosporine; Dose-Response Relationship, Immunologic; Electric Impedance; Female; Gene Expression Regulation, Developmental; Immunosuppressive Agents; Interferon-gamma; Ionophores; Kinetics; Pregnancy; Swine; Tetradecanoylphorbol Acetate; Trophoblasts | 2003 |
CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells.
Topics: Alkenes; Animals; Binding Sites; Calcineurin Inhibitors; Calcium; Cholecystokinin; Cyclic AMP; Cyclosporine; DNA-Binding Proteins; Enzyme Inhibitors; Marine Toxins; Okadaic Acid; Oxazoles; Pancreas; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Polyenes; Pyrones; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 2003 |
Modulation of CD40L antigen expression in Jurkat cells: involvement of protein kinase C activity.
Topics: Alkaloids; Benzophenanthridines; Calcineurin; CD4-Positive T-Lymphocytes; CD40 Antigens; CD40 Ligand; Cyclosporine; Enzyme Inhibitors; Humans; Ionomycin; Jurkat Cells; Lymphoma, T-Cell; Phenanthridines; Phosphoric Monoester Hydrolases; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 2003 |
Calcium signaling pathway involving calcineurin regulates interleukin-8 gene expression through activation of NF-kappaB in human osteoblast-like cells.
Topics: Antineoplastic Agents; Calcimycin; Calcineurin; Calcium Signaling; Cell Line; Cyclosporine; Gene Expression Regulation; Humans; Immunosuppressive Agents; Interleukin-8; Ionophores; NF-kappa B; Osteoblasts; Promoter Regions, Genetic; Tacrolimus; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2004 |
CD3 receptor modulation in Jurkat leukemic cell line.
Topics: Alkaloids; Benzophenanthridines; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Enzyme Inhibitors; Flow Cytometry; Gene Expression Regulation; Humans; Jurkat Cells; Phenanthridines; Protein Kinase C; Receptor-CD3 Complex, Antigen, T-Cell; Signal Transduction; Tetradecanoylphorbol Acetate | 2004 |
Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells.
Topics: Animals; Base Sequence; Blotting, Western; Calcineurin; Cells, Cultured; Cyclosporine; Deoxyribonuclease I; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Gene Expression Regulation; Genes, Reporter; Glutathione Transferase; HeLa Cells; Humans; Immunohistochemistry; Ionomycin; Luciferases; Lung; Mice; Models, Genetic; Molecular Sequence Data; Mutagenesis; NFATC Transcription Factors; Nuclear Proteins; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Pulmonary Surfactant-Associated Protein D; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroid Nuclear Factor 1; Transcription Factors; Transcription, Genetic; Transfection | 2004 |
Inhibitory effects of cyclosporin A on calcium mobilization-dependent interleukin-8 expression and invasive potential of human glioblastoma U251MG cells.
Topics: Calcimycin; Calcium; Cell Division; Cell Line, Tumor; Cyclosporine; Glioblastoma; Humans; I-kappa B Kinase; Interleukin-8; Neoplasm Invasiveness; NF-kappa B; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptors, Interleukin-8A; Receptors, Interleukin-8B; RNA, Messenger; Tetradecanoylphorbol Acetate | 2004 |
Effects of CD28 blockade on subsets of naïve T cells in cats.
Topics: Abatacept; Animals; Antigens, Protozoan; Cats; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Proliferation; Concanavalin A; Cyclosporine; Dexamethasone; Flow Cytometry; Immunoconjugates; Immunologic Memory; Immunosuppression Therapy; Ionomycin; Leukocytes, Mononuclear; Tetradecanoylphorbol Acetate; Toxoplasma | 2005 |
Phosphorylation-dependent desensitization by anandamide of vanilloid receptor-1 (TRPV1) function in rat skeletal muscle arterioles and in Chinese hamster ovary cells expressing TRPV1.
Topics: Animals; Arachidonic Acids; Arterioles; Calcineurin Inhibitors; Calcium Channel Blockers; Capsaicin; CHO Cells; Cricetinae; Cricetulus; Cyclosporine; Endocannabinoids; Muscle, Skeletal; Phosphorylation; Polyunsaturated Alkamides; Rats; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2006 |
A cytokine promoter/yellow fluorescent protein reporter transgene serves as an early activation marker of lymphocyte subsets.
Topics: Animals; Antigens; Bacterial Proteins; Base Sequence; Biomarkers; Cyclosporine; DNA, Recombinant; Gene Expression; Genes, Reporter; In Vitro Techniques; Interleukin-4; Ionomycin; Luminescent Proteins; Lymphocyte Activation; Lymphocyte Subsets; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ovalbumin; Peptide Fragments; Promoter Regions, Genetic; Recombinant Fusion Proteins; Tacrolimus; Tetradecanoylphorbol Acetate | 2005 |
Calcium-dependent expression of TNF-alpha in neural cells is mediated by the calcineurin/NFAT pathway.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcineurin; Calcium; Calcium Channel Agonists; Calcium Signaling; Cycloheximide; Cyclosporine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Immunosuppressive Agents; Ionophores; Neurons; NFATC Transcription Factors; Oligopeptides; PC12 Cells; Protein Synthesis Inhibitors; Rats; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2006 |
Cytokine analysis to predict immunosuppression.
Topics: Cyclosporine; Cytokines; Flow Cytometry; Heart Transplantation; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Interferon-gamma; Interleukin-10; Interleukin-2; Interleukin-4; Interleukin-6; Ionomycin; Mycophenolic Acid; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells; Tumor Necrosis Factor-alpha | 2006 |
NFAT induces breast cancer cell invasion by promoting the induction of cyclooxygenase-2.
Topics: Breast Neoplasms; Cell Line, Tumor; Collagen; Cyclooxygenase 2; Cyclosporine; Dinoprostone; Drug Combinations; Humans; Ionomycin; Ionophores; Laminin; Neoplasm Invasiveness; Neoplasm Metastasis; NFATC Transcription Factors; Proteoglycans; RNA, Small Interfering; Tetradecanoylphorbol Acetate | 2006 |
Distinct role of IL-3 promoter and enhancer region in murine mast cells.
Topics: Animals; Base Sequence; Calcimycin; Cyclosporine; Deoxyribonuclease I; Enhancer Elements, Genetic; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-3; Mast Cells; Mice; Molecular Sequence Data; Promoter Regions, Genetic; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2007 |
Validation of immunological biomarkers for the pharmacodynamic monitoring of immunosuppressive drugs in humans.
Topics: Adult; Antigens, CD; Biomarkers; CD4-Positive T-Lymphocytes; Cell Proliferation; Concanavalin A; Cyclosporine; Drug Monitoring; Humans; Immunosuppressive Agents; Interleukin-2; Interleukin-2 Receptor alpha Subunit; Lymphocyte Activation; Methylprednisolone; Middle Aged; Mycophenolic Acid; Receptors, Transferrin; Reproducibility of Results; Sirolimus; Tacrolimus; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
The influence of cyclosporin A on lymphocyte attenuator expression.
Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Autoimmune Diseases; Carcinogens; CD4-Positive T-Lymphocytes; Cells, Cultured; Cyclosporine; Female; Gene Expression Regulation; Graft Rejection; Immunosuppressive Agents; Interleukin-2; Interleukin-2 Receptor alpha Subunit; Lectins, C-Type; Lymphocyte Activation; Mice; Receptors, Immunologic; Self Tolerance; Sirolimus; Tetradecanoylphorbol Acetate; Transplantation Tolerance | 2007 |
Cytokine profiles of cord and adult blood leukocytes: differences in expression are due to differences in expression and activation of transcription factors.
Topics: Adult; Antigens, Surface; Cyclosporine; Cytokines; Female; Fetal Blood; Gene Expression Regulation; Hematopoiesis; Humans; Inhibitory Concentration 50; Kinetics; Leukocytes; Male; Middle Aged; RNA, Messenger; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells; Transcription Factors | 2007 |
Blocking mitochondrial permeability transition prevents p53 mitochondrial translocation during skin tumor promotion.
Topics: Animals; Bongkrekic Acid; Cell Line; Cyclosporine; Membrane Potentials; Mice; Mice, Inbred DBA; Mitochondria; Protein Transport; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2008 |
Effects of oral administration of ciclosporin A on skin carcinogenesis: a study using the two-stage carcinogenesis protocol in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Cyclosporine; Dose-Response Relationship, Drug; Female; Immunosuppressive Agents; Mice; Mice, Hairless; Neoplasm Staging; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Cyclosporine, an immunosuppressant, attenuates phorbol-induced lung injury in rats.
Topics: Acute Lung Injury; Animals; Cyclosporine; Immunosuppressive Agents; Luminescence; Lung; Nitric Oxide; Organ Size; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2008 |
Modification of the picryl chloride-induced allergic dermatitis model in mouse ear lobes by 12-O-tetradecanoylphorbol 13-acetate, and analysis of the role of histamine in the modified model.
Topics: Animals; Cell Count; Cimetidine; Cyclophosphamide; Cyclosporine; Cytokines; Dermatitis, Allergic Contact; Disease Models, Animal; Ear Auricle; Eosinophil Peroxidase; Eosinophils; Gene Expression; Histamine; Histamine Antagonists; Immunoglobulin E; Interferon-gamma; Interleukin-4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Picryl Chloride; Piperidines; Pyrilamine; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2009 |
Development of an in vitro test system measuring transcriptional downregulatory activities on IL-13.
Topics: Animals; Asthma; Carcinogens; Cell Line, Tumor; Cyclosporine; Down-Regulation; Drug Evaluation, Preclinical; Genes, Reporter; Humans; Immunosuppressive Agents; Interleukin-13; Ionomycin; Ionophores; Mice; Rats; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2009 |
Regulation of protease-activated receptor-1 by vasodilatory prostaglandins via NFAT.
Topics: Base Sequence; Cells, Cultured; Cyclosporine; DNA; Humans; Iloprost; Interleukin-6; Models, Biological; Myocytes, Smooth Muscle; NFATC Transcription Factors; Oligopeptides; Promoter Regions, Genetic; Prostaglandins; Receptor, PAR-1; RNA, Messenger; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Thrombin; Transcription, Genetic; Vasodilation | 2009 |
Calcineurin activation by slow calcium release from intracellular stores suppresses protein kinase C regulation of L-type calcium channels in L6 cells.
Topics: Animals; Calcineurin; Calcium; Calcium Channels, L-Type; Calcium-Transporting ATPases; Cell Line; Cyclosporine; Enzyme Inhibitors; Ion Channel Gating; Ion Transport; Myoblasts, Skeletal; Phorbol Esters; Protein Kinase C; Rats; Sarcoplasmic Reticulum; Tacrolimus; Tetradecanoylphorbol Acetate; Thapsigargin | 2009 |
Clinical relevance of curcumin-induced immunosuppression in living-related donor renal transplant: an in vitro analysis.
Topics: Acute Disease; Adult; Case-Control Studies; Cells, Cultured; Chronic Disease; Curcumin; Cyclosporine; Dose-Response Relationship, Drug; Female; Flow Cytometry; Graft Rejection; Humans; Immunosuppressive Agents; India; Interferon-gamma; Interleukin-4; Kidney Transplantation; Living Donors; Lymphocytes; Male; Middle Aged; Mitogens; NF-kappa B; Tetradecanoylphorbol Acetate; Time Factors; Young Adult | 2010 |
Whole blood flow cytometric measurement of NFATc1 and IL-2 expression to analyze cyclosporine A-mediated effects in T cells.
Topics: Animals; Biomarkers; Blood Preservation; CD4-Positive T-Lymphocytes; Cyclosporine; Flow Cytometry; Humans; Immunosuppressive Agents; Interleukin-2; Ionomycin; Ionophores; NFATC Transcription Factors; Reproducibility of Results; Tetradecanoylphorbol Acetate | 2010 |
CD28 costimulation regulates FOXP3 in a RelA/NF-κB-dependent mechanism.
Topics: Acetylation; Animals; Antibodies; B7-1 Antigen; CD28 Antigens; CD3 Complex; Cyclosporine; Forkhead Transcription Factors; HEK293 Cells; Histones; Humans; Interleukin-2 Receptor alpha Subunit; L Cells; Lymphocyte Activation; Mice; NF-kappa B; NFATC Transcription Factors; Promoter Regions, Genetic; Protein Binding; RNA, Small Interfering; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcriptional Activation; Transfection | 2011 |
Nuclear factor of activated T-cell c3 inhibition of mammalian target of rapamycin signaling through induction of regulated in development and DNA damage response 1 in human intestinal cells.
Topics: Calcimycin; Calcineurin Inhibitors; Cell Differentiation; Cyclosporine; Gene Expression Regulation; HCT116 Cells; HT29 Cells; Humans; Intestinal Mucosa; Intestines; NFATC Transcription Factors; Signal Transduction; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Transcription Factors; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2012 |
Megakaryocytic differentiation of K562 cells induced by PMA reduced the activity of respiratory chain complex IV.
Topics: Adenosine Triphosphate; Cell Differentiation; Cyclosporine; Electron Transport Complex IV; Humans; Immunoblotting; K562 Cells; Megakaryocytes; Membrane Potential, Mitochondrial; Microscopy, Confocal; Microscopy, Electron, Transmission; Mitochondria; Mitochondrial Proteins; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2014 |
The 18-kDa Translocator Protein Inhibits Vascular Cell Adhesion Molecule-1 Expression via Inhibition of Mitochondrial Reactive Oxygen Species.
Topics: Adenoviridae; Cyclosporine; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Intercellular Adhesion Molecule-1; Mitochondria; Reactive Oxygen Species; Receptors, GABA; Tetradecanoylphorbol Acetate; Vascular Cell Adhesion Molecule-1 | 2015 |
Perturbed Calcineurin-NFAT Signaling Is Associated with the Development of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Calcineurin; Calcineurin Inhibitors; Calcium Ionophores; Cell Line, Tumor; Cyclosporine; DNA-Binding Proteins; Down Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Luciferases; Muscle Proteins; Neprilysin; NFATC Transcription Factors; RNA, Messenger; Signal Transduction; tau Proteins; Tetradecanoylphorbol Acetate | 2016 |
Effect of immunosuppressive drugs on cytokine production in canine whole blood stimulated with lipopolysaccharide or a combination of ionomycin and phorbol 12-myristate 13-acetate.
Topics: Animals; Azathioprine; Cyclosporine; Dogs; Immunosuppressive Agents; Interferon-gamma; Interleukins; Ionomycin; Leflunomide; Lipopolysaccharides; Mycophenolic Acid; Prednisone; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2019 |