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tetradecanoylphorbol acetate and curcumin

tetradecanoylphorbol acetate has been researched along with curcumin in 82 studies

Research

Studies (82)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.22)18.7374
1990's32 (39.02)18.2507
2000's26 (31.71)29.6817
2010's23 (28.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Conney, AH; Deschner, EE; Ferraro, TA; Huang, MT; Newmark, HL; Wang, ZY1
Abidi, TF; Conney, AH; Ferraro, T; Huang, MT; Laskin, JD; Lysz, T1
Huang, TS; Lee, SC; Lin, JK1
Abidi, TF; Conney, AH; Ferraro, T; Huang, MT; Laskin, JD; Lysz, T; Manchand, PS1
Shalini, VK; Srinivas, L1
Conney, AH; Huang, MT; Smart, RC; Wong, CQ1
Hsieh, JS; Huang, TS; Kuo, ML; Lin, JK1
Chang, RL; Conney, AH; Fisher, C; Huang, MT; Lu, YP; Ma, W; Manchand, PS; Newmark, HL1
Kakar, SS; Roy, D1
Chang, RL; Conney, AH; Huang, MT; Lou, YR; Lu, YP; Newmark, HL; Reuhl, KR1
Lin, JK; Shih, CA2
Chang, RL; Conney, AH; Huang, MT; Lu, YP1
Lin, JK; Lin, SJ; Liu, JY1
Iijima, M; Ishizaki, C; Oguro, T; Sueki, H; Wen, CQ; Yoshida, T1
Conney, AH; Frenkel, K; Grunberger, D; Han, J; Huang, MT; Ma, W; Xie, JG; Yen, P1
Chen, X; Fu, Z; Han, R; Li, Y1
Apisariyakul, A; Dunn, FW; Limtrakul, P; Lipigorngoson, S; Namwong, O1
Lee, SF; Lin, JK1
Chang, RL; Conney, AH; Huang, MT; Liu, Y; Lou, YR; Newmark, HL; Osawa, T; Xie, JG1
Hanada, K; Kawasaki, K; Nishijima, M; Yamamoto, H1
Joe, B; Lokesh, BR1
Pendurthi, UR; Rao, LV; Williams, JT1
Kondo, A; Morimoto, T; Okazaki, K1
Murakami, A; Nakamura, Y; Ohigashi, H; Ohto, Y; Osawa, T1
Chun, KS; Lee, JM; Lee, SS; Park, KK; Surh, YJ1
Bondada, S; Elliott, L; Johnston, TD; Nagabhushan, M; Ranjan, D; Wu, G1
Cetindag, C; Harteneck, C; Höer, A; Oberdisse, E; Schöneberg, T1
Abe, Y; Hashimoto, S; Horie, T1
Altorki, NK; Dannenberg, AJ; Mestre, JR; Subbaramaiah, K; Zhang, F1
Konoshima, T; Motohashi, N; Mukainaka, T; Nishino, H; Okuda, M; Okuda, Y; Saito, Y; Tokuda, H; Yamagami, C1
Chun, KS; Kim, HS; Kim, OH; Lee, JM; Lee, SS; Moon, A; Park, KK; Sohn, Y; Surh, YJ1
Farrow, S; Holloway, KA; Howells, L; Kaptein, A; Manson, MM; Munks, RJ; Plummer, SM1
Pendurthi, UR; Rao, LV1
Han, SS; Keum, YS; Lee, SS; Seo, HJ; Surh, YJ1
Gescher, A; Howells, L; Ireson, C; Jones, DJ; Jukes, R; Lim, CK; Luo, JL; Orr, S; Plummer, S; Steward, WP; Verschoyle, R; Williams, M1
Anuchapreeda, S; Dunn, FW; Limtrakul, P; Lipigorngoson, S1
Grant, S; Vrana, JA1
Oguro, T; Yoshida, T1
Ardaillou, N; Ardaillou, R; Bretot, X; Dussaule, JC; Placier, S1
Cheng, AL; Hergenhahn, M; Hsu, CH; Polack, A; Rösl, F; Soto, U; Weninger, A1
Cheng, AL; Chuang, SE; Gao, M; Lai, GM; Liao, CM; Lu, YS; Yeh, PY1
Han, SS; Keum, YS; Seo, HJ; Surh, YJ1
Gertsch, J; Güttinger, M; Heilmann, J; Sticher, O1
Chun, KS; Han, SS; Keum, YS; Kim, SH; Song, YS; Surh, YJ1
Delhalle, S; Dicato, M; Diederich, M; Duvoix, A; Galteau, MM; Morceau, F; Schmitz, M; Schnekenburger, M1
Hirota, M; Ishidoh, T; Kamisuki, S; Koiwai, O; Mizushina, Y; Murakami, C; Perpelescu, M; Sakaguchi, K; Shimazaki, N; Sugawara, F; Suzuki, M; Takemura, M; Yoshida, H1
Balasubramanyam, M; Koteswari, AA; Kumar, RS; Maheswari, JU; Mohan, V; Monickaraj, SF1
Aggarwal, B; Boyd, DD; Wang, H; Yan, C1
Chang, KC; Kang, YJ; Kim, HJ; Ko, YS; Lee, YS; Park, MK; Pyo, HS; Seo, HG; Yun-Choi, HS1
Gho, YS; Hahm, ER; Kim, KW; Park, C; Park, S; Yang, CH1
Jinnno, K; Masuda, M; Mou, XY; Murakoshi, M; Nishino, H; Osaka, Y; Satomi, Y; Takayasu, J; Tokuda, H; Wada, S; Yano, M; Yogosawa, S1
Manhart, N; Roth, E; Strasser, EM; Wessner, B1
Deck, LM; Gonzales, AM; Heynekamp, JJ; Hunsaker, LA; Orlando, RA; Vander Jagt, DL; Weber, WM1
Anda, T; Kaminogo, M; Kitange, G; Nagata, I; Shabani, HK; Shibata, S; Tsunoda, K1
Garg, R; Maru, GB; Ramchandani, AG1
Bauerová, K; Drábiková, K; Jancinová, V; Kostálová, D; Nosál, R; Perecko, T1
Kwon, TK; Lim, JH1
Lee, KH; Nakagawa-Goto, K; Tatsuzaki, J; Tokuda, H1
Agarwal, SK; Bharti, AC; Bhowmik, DM; Guleria, S; Gupta, N; Kumar, R; Mehra, NK; Panigrahi, A; Sharma, PK; Shukla, S1
Ahmed, A; Deobagkar, M; Mukherjee, S; Naik, T; Nandi, D1
Li, M; Liu, W; Luo, J; Yang, J; Yu, BY; Zhuang, SM1
Ho, CT; Huang, MT; Lin, CC; Liu, Y1
Chang, TW; Deng, YT; Lee, MS; Lin, JK1
Dange, P; Kailaje, V; Kumar, G; Maru, GB; Ramchandani, AG; Vaidya, MM1
Hwang, BM; Hwang, JK; Jung, SH; Kim, BS; Kim, JM; Kim, JS; Kwon, KB; Lee, SH; Lee, SJ; Lee, YR; Noh, EM; You, YO; Youn, HJ1
Becker, T; Dietersdorfer, E; Kiener, H; Kloesch, B; Steiner, G1
Chiou, SY; Ho, CT; Kou, MC; Wang, L; Weng, CY; Wu, MJ1
Conney, AH; Du, ZY; Huang, MT; Liu, Y; Wei, X; Zhang, K; Zheng, X1
Azzi, A; Dolnikowski, GG; Kim, SH; Meydani, M; Miyazawa, T; Nakagawa, K; Thomas, MJ; Zingg, JM1
Cao, J; Chen, K; Fan, Y; Han, Z; Huang, W; Huang, Z; Tian, L; Wang, C; Ye, B1
Hu, J; Jin, H; Sun, J; Zhao, Y1
Andoh, T; Ichikawa, H; Kuriyama, I; Lee-Hiraiwa, E; Mizushina, Y; Onodera, T; Sakamoto, Y1
Abdul Hamid, R; Khaza'ai, H; Mohtarrudin, N; Saiful Yazan, L; Yeong, LT1
Babica, P; Čtveráčková, L; Lenčešová, Z; Trosko, JE; Upham, BL1
Kang, OH; Kim, SA; Kong, R; Kwon, DY; Seo, YS; Shin, DW; Zhou, T1
DiGiovanni, J; Rho, O; Slaga, TJ; Tremmel, L1
Du, Z; Gao, Z; Han, Y; Pan, C; Rakariyatham, K; Song, M; Tang, Z; Wu, X; Xiao, H; Yuan, B; Zhang, G1
Piyachaturawat, P; Sodsai, A; Sophasan, S; Suksamrarn, A; Vongsakul, M1
Chung, WY; Hwang, JK; Kim, MJ; Park, JH; Park, KK; Park, SK1
Kim, Y; Kim, YH; Lee, SJ; Park, SY1
Agarwal, K; Bawankule, DU; Chanda, D; Kumar, A; Maurya, AK; Saxena, A; Singh, M; Tandon, S; Yadav, A; Yadav, P1

Reviews

2 review(s) available for tetradecanoylphorbol acetate and curcumin

ArticleYear
Inhibitory effect of curcumin and some related dietary compounds on tumor promotion and arachidonic acid metabolism in mouse skin.
    Advances in enzyme regulation, 1991, Volume: 31

    Topics: Arachidonic Acid; Arachidonic Acids; Carcinogens; Curcumin; Diet; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1991
Some perspectives on dietary inhibition of carcinogenesis: studies with curcumin and tea.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1997, Volume: 216, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Arachidonic Acid; Calcitriol; Carcinogens; Cell Differentiation; Chemoprevention; Curcumin; Diet; Humans; Mice; Neoplasms, Experimental; Tea; Tetradecanoylphorbol Acetate; Tretinoin

1997

Other Studies

80 other study(ies) available for tetradecanoylphorbol acetate and curcumin

ArticleYear
Effect of dietary curcumin and ascorbyl palmitate on azoxymethanol-induced colonic epithelial cell proliferation and focal areas of dysplasia.
    Cancer letters, 1992, Jun-15, Volume: 64, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Body Weight; Colon; Curcumin; Diet; Epithelium; Female; Methylazoxymethanol Acetate; Mice; Tetradecanoylphorbol Acetate

1992
Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis.
    Cancer research, 1991, Feb-01, Volume: 51, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Chlorogenic Acid; Coumaric Acids; Curcumin; Dermatitis, Contact; Female; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Lipoxygenase; Mice; Peroxidases; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate

1991
Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Jun-15, Volume: 88, Issue:12

    Topics: Animals; Base Sequence; Blotting, Northern; Carcinogens; Cells, Cultured; Curcumin; DNA-Binding Proteins; Fibroblasts; Mice; Molecular Sequence Data; Nucleic Acid Hybridization; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic

1991
Fuel smoke condensate induced DNA damage in human lymphocytes and protection by turmeric (Curcuma longa).
    Molecular and cellular biochemistry, 1990, Jun-01, Volume: 95, Issue:1

    Topics: Catechols; Curcumin; DNA; DNA Damage; Fluorescence; Humans; Lymphocytes; Smoke; Tetradecanoylphorbol Acetate

1990
Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1988, Nov-01, Volume: 48, Issue:21

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Catechols; Chlorogenic Acid; Cinnamates; Coumaric Acids; Curcumin; DNA; Edema; Female; Mice; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1988
A labile hyperphosphorylated c-Fos protein is induced in mouse fibroblast cells treated with a combination of phorbol ester and anti-tumor promoter curcumin.
    Cancer letters, 1995, Sep-04, Volume: 96, Issue:1

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antineoplastic Agents; Base Sequence; Carcinogens; Curcumin; Gene Expression; Genes, fos; Genes, jun; In Vitro Techniques; Leupeptins; Mice; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protease Inhibitors; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate

1995
Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Line; Cell Transformation, Neoplastic; Coumaric Acids; Curcumin; Diarylheptanoids; Dose-Response Relationship, Drug; Enzyme Induction; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors

1995
Curcumin inhibits TPA induced expression of c-fos, c-jun and c-myc proto-oncogenes messenger RNAs in mouse skin.
    Cancer letters, 1994, Nov-25, Volume: 87, Issue:1

    Topics: Animals; Blotting, Northern; Curcumin; Densitometry; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Genes, myc; Mice; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate

1994
Effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate- and ultraviolet B light-induced expression of c-Jun and c-Fos in JB6 cells and in mouse epidermis.
    Carcinogenesis, 1994, Volume: 15, Issue:10

    Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Curcumin; Drug Interactions; Female; Gene Expression Regulation; Hyperplasia; Mice; Mice, Hairless; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays

1994
Inhibitory effect of curcumin on xanthine dehydrogenase/oxidase induced by phorbol-12-myristate-13-acetate in NIH3T3 cells.
    Carcinogenesis, 1994, Volume: 15, Issue:8

    Topics: 3T3 Cells; Animals; Curcumin; Enzyme Induction; Mice; Tetradecanoylphorbol Acetate; Uric Acid; Xanthine Dehydrogenase; Xanthine Oxidase

1994
Inhibitory effect of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced increase in ornithine decarboxylase mRNA in mouse epidermis.
    Carcinogenesis, 1993, Volume: 14, Issue:2

    Topics: Animals; Curcumin; Drug Interactions; Enzyme Induction; Epidermis; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; RNA, Messenger; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transcription, Genetic

1993
Inhibition of 8-hydroxydeoxyguanosine formation by curcumin in mouse fibroblast cells.
    Carcinogenesis, 1993, Volume: 14, Issue:4

    Topics: 3T3 Cells; 8-Hydroxy-2'-Deoxyguanosine; Animals; Curcumin; Deoxyguanosine; Hydroxylation; Lipid Peroxidation; Mice; Tetradecanoylphorbol Acetate

1993
Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells.
    Carcinogenesis, 1993, Volume: 14, Issue:5

    Topics: 3T3 Cells; Animals; Blotting, Western; Chromatography, DEAE-Cellulose; Curcumin; Cysteine; Cytosol; Dithiothreitol; Glutathione; Kinetics; Mercaptoethanol; Mice; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate

1993
Enhancing effect of ultraviolet A on ornithine decarboxylase induction and dermatitis evoked by 12-o-tetradecanoylphorbol-13-acetate and its inhibition by curcumin in mouse skin.
    Dermatology (Basel, Switzerland), 1996, Volume: 193, Issue:4

    Topics: Animals; Curcumin; Dermatitis; Disease Models, Animal; Drug Interactions; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin; Tetradecanoylphorbol Acetate; Ultraviolet Rays

1996
Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis.
    Carcinogenesis, 1997, Volume: 18, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Carcinogens; Curcumin; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Mice; Neoplasms, Experimental; Oxidation-Reduction; Skin Neoplasms; Tetradecanoylphorbol Acetate

1997
[Effects of curcumin derivatives on the GJIC of normal and tumor cells].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1996, Volume: 18, Issue:2

    Topics: 3T3 Cells; Adenocarcinoma; Animals; Antineoplastic Agents; Carcinogens; Cell Communication; Cells, Cultured; Cricetinae; Curcumin; Fetus; Gap Junctions; Humans; Liver; Lung; Lung Neoplasms; Mice; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Inhibitory effect of dietary curcumin on skin carcinogenesis in mice.
    Cancer letters, 1997, Jun-24, Volume: 116, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Curcumin; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate

1997
Inhibitory effects of phytopolyphenols on TPA-induced transformation, PKC activation, and c-jun expression in mouse fibroblast cells.
    Nutrition and cancer, 1997, Volume: 28, Issue:2

    Topics: 3T3 Cells; Animals; Carcinogens; Catechin; Cell Line; Cell Transformation, Neoplastic; Curcumin; Down-Regulation; Fibroblasts; Flavonoids; Flavonols; Gene Expression Regulation, Neoplastic; Genes, jun; Mice; Phenols; Polymers; Protein Kinase C; Tetradecanoylphorbol Acetate

1997
Inhibitory effect on curcumin on mammalian phospholipase D activity.
    FEBS letters, 1997, Nov-10, Volume: 417, Issue:2

    Topics: Animals; Bacillus subtilis; Bacterial Proteins; Cattle; Cell-Free System; Cells, Cultured; Curcumin; Enzyme Activation; Enzyme Inhibitors; Mice; Phospholipase D; Phospholipases A; Phospholipases A2; Sphingomyelin Phosphodiesterase; Tetradecanoylphorbol Acetate; Type C Phospholipases

1997
Effect of curcumin and capsaicin on arachidonic acid metabolism and lysosomal enzyme secretion by rat peritoneal macrophages.
    Lipids, 1997, Volume: 32, Issue:11

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Capsaicin; Collagenases; Curcumin; Dinoprostone; Hyaluronoglucosaminidase; Leukotriene B4; Leukotriene C4; Lysosomes; Macrophages, Peritoneal; Male; Membrane Lipids; Pancreatic Elastase; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

1997
Inhibition of tissue factor gene activation in cultured endothelial cells by curcumin. Suppression of activation of transcription factors Egr-1, AP-1, and NF-kappa B.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:12

    Topics: Cells, Cultured; Curcumin; DNA-Binding Proteins; Early Growth Response Protein 1; Endothelium, Vascular; Gene Expression; Gene Expression Regulation; Humans; I-kappa B Proteins; Immediate-Early Proteins; Lipopolysaccharides; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; RNA, Messenger; Tetradecanoylphorbol Acetate; Thrombin; Thromboplastin; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha

1997
Detection of antitumor promoting activity in Raji cells carrying Epstein-Barr virus genome by immunoblotting analysis.
    Bioscience, biotechnology, and biochemistry, 1998, Volume: 62, Issue:2

    Topics: Animals; Antibodies, Viral; Antigens, Viral; Blotting, Western; Butyrates; Butyric Acid; Carcinogens; Cell Line, Transformed; Curcumin; Electrophoresis, Polyacrylamide Gel; Genome, Viral; Herpesvirus 4, Human; Histamine Antagonists; Humans; Immunoblotting; Mice; Microscopy, Fluorescence; Staurosporine; Tetradecanoylphorbol Acetate

1998
Inhibitory effects of curcumin and tetrahydrocurcuminoids on the tumor promoter-induced reactive oxygen species generation in leukocytes in vitro and in vivo.
    Japanese journal of cancer research : Gann, 1998, Volume: 89, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Antigens, Viral; Curcumin; Edema; Female; Fluorescent Antibody Technique, Indirect; Hydrogen Peroxide; Leukocytes; Mice; Mice, Inbred ICR; Oxidative Stress; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1998
Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice.
    Cancer letters, 1998, Jul-17, Volume: 129, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capillary Permeability; Catechols; Curcumin; Epidermis; Fatty Alcohols; Female; Inflammation; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate

1998
Curcumin blocks cyclosporine A-resistant CD28 costimulatory pathway of human T-cell proliferation.
    The Journal of surgical research, 1998, Jul-01, Volume: 77, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinogens; CD28 Antigens; Cell Division; Cells, Cultured; Curcumin; Cyclosporine; Humans; Immunosuppressive Agents; T-Lymphocytes; Tetradecanoylphorbol Acetate

1998
Enhancement of phospholipase D activity following baculovirus and adenovirus infection in Sf9 and COS-7 cells.
    Biochimica et biophysica acta, 1998, Aug-28, Volume: 1393, Issue:2-3

    Topics: Adenoviridae; Adenoviridae Infections; ADP-Ribosylation Factors; Animals; Baculoviridae; Cell Line; COS Cells; Curcumin; GTP-Binding Proteins; Insecta; Phospholipase D; Tetradecanoylphorbol Acetate; Transfection

1998
Curcumin inhibition of inflammatory cytokine production by human peripheral blood monocytes and alveolar macrophages.
    Pharmacological research, 1999, Volume: 39, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Curcumin; Cytokines; Dose-Response Relationship, Drug; Female; Humans; Lipopolysaccharides; Macrophages, Alveolar; Male; Middle Aged; Monocytes; Tetradecanoylphorbol Acetate; Time Factors

1999
Curcumin inhibits cyclooxygenase-2 transcription in bile acid- and phorbol ester-treated human gastrointestinal epithelial cells.
    Carcinogenesis, 1999, Volume: 20, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Chenodeoxycholic Acid; Curcumin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Digestive System; Enzyme Induction; Gastric Mucosa; Humans; Intestinal Mucosa; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic

1999
Inhibitory effects of dehydrozingerone and related compounds on 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation.
    Cancer letters, 1998, Dec-11, Volume: 134, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antigens, Viral; Carcinogens; Curcumin; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Inhibitory Concentration 50; Structure-Activity Relationship; Styrenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1998
Anti-tumor promoting potential of naturally occurring diarylheptanoids structurally related to curcumin.
    Mutation research, 1999, Jul-16, Volume: 428, Issue:1-2

    Topics: 3T3 Cells; Animals; Brain; Carcinogens; Curcumin; Diarylheptanoids; Guaiacol; HL-60 Cells; Humans; In Vitro Techniques; Lipid Peroxidation; Male; Mice; Neoplasms; Ornithine Decarboxylase Inhibitors; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

1999
Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex.
    Oncogene, 1999, Oct-28, Volume: 18, Issue:44

    Topics: Antineoplastic Agents; Caffeic Acids; Colonic Neoplasms; Curcumin; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; I-kappa B Kinase; I-kappa B Proteins; Isoenzymes; Membrane Proteins; NF-kappa B; NF-kappaB-Inducing Kinase; Phenylethyl Alcohol; Polyenes; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1999
Suppression of transcription factor Egr-1 by curcumin.
    Thrombosis research, 2000, Feb-15, Volume: 97, Issue:4

    Topics: Binding Sites; Blood; Cells, Cultured; Curcumin; DNA-Binding Proteins; Drug Interactions; Early Growth Response Protein 1; Endothelium, Vascular; Fibroblasts; Gene Expression Regulation; Humans; Immediate-Early Proteins; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Tetradecanoylphorbol Acetate; Thromboplastin; Transcription Factors

2000
Inhibitory effects of curcumin and capsaicin on phorbol ester-induced activation of eukaryotic transcription factors, NF-kappaB and AP-1.
    BioFactors (Oxford, England), 2000, Volume: 12, Issue:1-4

    Topics: Animals; Anticarcinogenic Agents; Capsaicin; Curcumin; Female; HL-60 Cells; Humans; Mice; Mice, Inbred ICR; NF-kappa B; Skin; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2000
Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production.
    Cancer research, 2001, Feb-01, Volume: 61, Issue:3

    Topics: Adult; Animals; Anticarcinogenic Agents; Chromatography, High Pressure Liquid; Colon; Curcumin; Cyclooxygenase 2; Dinoprostone; Drug Interactions; Epithelial Cells; Female; Glucuronides; Hepatocytes; Humans; Intestinal Mucosa; Isoenzymes; Male; Mass Spectrometry; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate

2001
Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin.
    BMC cancer, 2001, Volume: 1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Carcinogens; Curcumin; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, fos; Genes, ras; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate

2001
Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
    Blood, 2001, Apr-01, Volume: 97, Issue:7

    Topics: Acetylcysteine; Amanitins; Aminoacetonitrile; Apoptosis; Benzoquinones; Bryostatins; Butadienes; Curcumin; Cysteine Endopeptidases; Dactinomycin; Diterpenes; Drug Synergism; Enzyme Activation; Flavonoids; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Lactones; Macrolides; Maleimides; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Nitriles; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Quinones; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Type C Phospholipases; U937 Cells; Ubiquitins

2001
Effect of ultraviolet A on ornithine decarboxylase and metallothionein gene expression in mouse skin.
    Photodermatology, photoimmunology & photomedicine, 2001, Volume: 17, Issue:2

    Topics: Animals; Antioxidants; Blotting, Northern; Curcumin; Enzyme Induction; Enzyme Inhibitors; Female; Gene Expression; Metallothionein; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Piperazines; Radiation-Protective Agents; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Vitamin E

2001
Regulation of ANP clearance receptors by EGF in mesangial cells from NOD mice.
    American journal of physiology. Renal physiology, 2001, Volume: 281, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Autoradiography; Cell Line; Curcumin; Cyclic GMP; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Glomerular Mesangium; Guanylate Cyclase; Insulin-Like Growth Factor I; Mice; Mice, Inbred NOD; Platelet-Derived Growth Factor; Radioligand Assay; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Tetradecanoylphorbol Acetate

2001
The chemopreventive compound curcumin is an efficient inhibitor of Epstein-Barr virus BZLF1 transcription in Raji DR-LUC cells.
    Molecular carcinogenesis, 2002, Volume: 33, Issue:3

    Topics: Anticarcinogenic Agents; Carcinogens; Curcumin; DNA-Binding Proteins; Gene Expression Regulation, Viral; Genes, Reporter; Herpesvirus 4, Human; Humans; Kinetics; Luciferases; Promoter Regions, Genetic; RNA, Viral; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured; Viral Proteins; Virus Latency

2002
Basal levels and patterns of anticancer drug-induced activation of nuclear factor-kappaB (NF-kappaB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells.
    Biochemical pharmacology, 2002, May-01, Volume: 63, Issue:9

    Topics: Active Transport, Cell Nucleus; Antineoplastic Agents; Curcumin; Dexamethasone; DNA-Binding Proteins; Doxorubicin; Drug Hypersensitivity; Drug Interactions; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2002
Curcumin suppresses activation of NF-kappaB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells.
    Journal of biochemistry and molecular biology, 2002, May-31, Volume: 35, Issue:3

    Topics: Anticarcinogenic Agents; Carcinogens; Consensus Sequence; Curcumin; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Genes, Regulator; HL-60 Cells; Humans; I-kappa B Proteins; Leukemia, Myeloid; NF-kappa B; NF-KappaB Inhibitor alpha; Promoter Regions, Genetic; Protein Transport; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2002
Curcumin differentially modulates mRNA profiles in Jurkat T and human peripheral blood mononuclear cells.
    Bioorganic & medicinal chemistry, 2003, Mar-20, Volume: 11, Issue:6

    Topics: Cell Survival; Curcumin; Cytokines; DNA Primers; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Humans; In Vitro Techniques; Interleukin-2; Jurkat Cells; Mitogens; Monocytes; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors

2003
Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activation.
    Carcinogenesis, 2003, Volume: 24, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Curcumin; Cyclooxygenase 2; Enzyme Activation; Female; I-kappa B Proteins; Isoenzymes; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Skin; Tetradecanoylphorbol Acetate

2003
Induction of apoptosis by curcumin: mediation by glutathione S-transferase P1-1 inhibition.
    Biochemical pharmacology, 2003, Oct-15, Volume: 66, Issue:8

    Topics: Apoptosis; Cell Survival; Curcumin; Drug Interactions; Enzyme Inhibitors; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Isoenzymes; K562 Cells; NF-kappa B; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Tumor Necrosis Factor-alpha

2003
Some anti-chronic inflammatory compounds are DNA polymerase lambda-specific inhibitors.
    Biochemical pharmacology, 2003, Nov-15, Volume: 66, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Caffeic Acids; Cell Division; Curcumin; DNA Polymerase beta; Enzyme Inhibitors; Humans; Inflammation; Mice; Phenols; Tetradecanoylphorbol Acetate

2003
Curcumin-induced inhibition of cellular reactive oxygen species generation: novel therapeutic implications.
    Journal of biosciences, 2003, Volume: 28, Issue:6

    Topics: Calcium; Case-Control Studies; Curcumin; Diabetes Mellitus; Humans; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

2003
A novel homologous recombination system to study 92 kDa type IV collagenase transcription demonstrates that the NF-kappaB motif drives the transition from a repressed to an activated state of gene expression.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:3

    Topics: Cell Line; Curcumin; DNA Nucleotidyltransferases; DNA, Complementary; Enzyme Induction; Gene Expression Regulation, Enzymologic; Genes, Reporter; Genes, Synthetic; Genetic Vectors; Humans; Hydroxamic Acids; Luciferases; Matrix Metalloproteinase 9; NF-kappa B; Plasmids; Promoter Regions, Genetic; Recombination, Genetic; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection

2004
Induction of manganese-superoxide dismutase by YS 51, a synthetic 1-(beta-naphtylmethyl)6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline alkaloid: implication for anti-inflammatory actions.
    Pharmacology, 2004, Volume: 71, Issue:2

    Topics: Animals; Blotting, Northern; Curcumin; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Flavonoids; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phorbol Esters; Phosphorylation; Pulmonary Artery; Pyridines; RNA, Messenger; Sheep; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tetrahydroisoquinolines; Tumor Necrosis Factor-alpha

2004
Synthetic curcumin analogs inhibit activator protein-1 transcription and tumor-induced angiogenesis.
    Biochemical and biophysical research communications, 2004, Aug-20, Volume: 321, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Chick Embryo; Curcumin; Down-Regulation; Humans; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Umbilical Cord; Vascular Endothelial Growth Factor A

2004
Cancer prevention by antioxidants.
    BioFactors (Oxford, England), 2004, Volume: 22, Issue:1-4

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Beverages; Carotenoids; Curcumin; Lycopene; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Peroxynitrous Acid; Skin Neoplasms; Solanum lycopersicum; Tetradecanoylphorbol Acetate

2004
The relationship between the anti-inflammatory effects of curcumin and cellular glutathione content in myelomonocytic cells.
    Biochemical pharmacology, 2005, Aug-15, Volume: 70, Issue:4

    Topics: Anti-Inflammatory Agents; Cell Differentiation; Curcumin; Glutathione; Humans; Lipopolysaccharides; Monocytes; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2005
TPA-induced up-regulation of activator protein-1 can be inhibited or enhanced by analogs of the natural product curcumin.
    Biochemical pharmacology, 2006, Oct-16, Volume: 72, Issue:8

    Topics: Animals; Antioxidants; Cell Line; Curcumin; Cyclooxygenase 2; Humans; Mice; Microglia; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Up-Regulation

2006
Expression of the constitutively activated RelA/NF-kappaB in human astrocytic tumors and the in vitro implication in the regulation of urokinase-type plasminogen activator, migration, and invasion.
    Brain tumor pathology, 2005, Volume: 22, Issue:2

    Topics: Astrocytoma; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; Culture Media, Conditioned; Curcumin; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Neoplasm Invasiveness; Neoplasm Proteins; NF-kappa B; Oligonucleotides, Antisense; Retrospective Studies; RNA, Messenger; RNA, Neoplasm; Single-Blind Method; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Urokinase-Type Plasminogen Activator

2005
Curcumin decreases 12-O-tetradecanoylphorbol-13-acetate-induced protein kinase C translocation to modulate downstream targets in mouse skin.
    Carcinogenesis, 2008, Volume: 29, Issue:6

    Topics: Animals; Antineoplastic Agents; Curcumin; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Female; Immunoblotting; Isoenzymes; Mice; Mice, Nude; Protein Kinase C; Protein Transport; Signal Transduction; Skin; Tetradecanoylphorbol Acetate

2008
Decreased activity of neutrophils in the presence of diferuloylmethane (curcumin) involves protein kinase C inhibition.
    European journal of pharmacology, 2009, Jun-10, Volume: 612, Issue:1-3

    Topics: Adenosine Triphosphate; Adult; Animals; Arthritis, Experimental; Carcinogens; Curcumin; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Kinetics; Luciferases, Renilla; Luminescence; Luminescent Measurements; Male; Middle Aged; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred Lew; Respiratory Burst; Tetradecanoylphorbol Acetate; Young Adult

2009
Curcumin inhibits phorbol myristate acetate (PMA)-induced MCP-1 expression by inhibiting ERK and NF-kappaB transcriptional activity.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:1

    Topics: Antineoplastic Agents; Blotting, Western; Cell Nucleus; Chemokine CCL2; Coloring Agents; Curcumin; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Humans; Luciferases; NF-kappa B; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Transcription Factor AP-1; Transcription, Genetic; Transfection; U937 Cells

2010
Cancer preventive agents 10. Prenylated dehydrozingerone analogs as potent chemopreventive agents.
    Journal of Asian natural products research, 2010, Volume: 12, Issue:3

    Topics: Anticarcinogenic Agents; Antigens, Viral; Carcinogens; Combinatorial Chemistry Techniques; Curcumin; Molecular Structure; Stereoisomerism; Styrenes; Tetradecanoylphorbol Acetate

2010
Clinical relevance of curcumin-induced immunosuppression in living-related donor renal transplant: an in vitro analysis.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2010, Volume: 8, Issue:2

    Topics: Acute Disease; Adult; Case-Control Studies; Cells, Cultured; Chronic Disease; Curcumin; Cyclosporine; Dose-Response Relationship, Drug; Female; Flow Cytometry; Graft Rejection; Humans; Immunosuppressive Agents; India; Interferon-gamma; Interleukin-4; Kidney Transplantation; Living Donors; Lymphocytes; Male; Middle Aged; Mitogens; NF-kappa B; Tetradecanoylphorbol Acetate; Time Factors; Young Adult

2010
Rapid burst of H2O2 by plant growth regulators increases intracellular Ca2+ amounts and modulates CD4+ T cell activation.
    International immunopharmacology, 2010, Volume: 10, Issue:11

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Calcium; CD3 Complex; CD4-Positive T-Lymphocytes; Cell Cycle; Curcumin; Female; Hydrogen Peroxide; Indoleacetic Acids; Interferon-gamma; Interleukin-2; Ionomycin; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Naphthaleneacetic Acids; Plant Growth Regulators; Receptors, Antigen, T-Cell; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2010
Identification of Siah-interacting protein as a potential regulator of apoptosis and curcumin resistance.
    Oncogene, 2010, Dec-02, Volume: 29, Issue:48

    Topics: Active Transport, Cell Nucleus; Antineoplastic Agents; Apoptosis; Calcium-Binding Proteins; Cell Line, Tumor; Curcumin; Drug Resistance, Neoplasm; Humans; Phosphorylation; Tetradecanoylphorbol Acetate

2010
Inhibitory effects of 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, β-diketone structural analogues of curcumin, on chemical-induced tumor promotion and inflammation in mouse skin.
    Food & function, 2011, Volume: 2, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Aspirin; Carcinogens; Curcumin; Dermatitis; Ear, External; Edema; Female; Ketones; Mice; Mice, Inbred Strains; Platelet Aggregation Inhibitors; Skin Neoplasms; Tetradecanoylphorbol Acetate

2011
Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in C2C12 mouse skeletal muscle cells.
    Journal of agricultural and food chemistry, 2012, Feb-01, Volume: 60, Issue:4

    Topics: Animals; Catechin; Cell Line; Curcumin; Enzyme Activation; Fatty Acids, Nonesterified; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Muscle, Skeletal; Palmitic Acid; Phosphorylation; Polyphenols; Protein Kinase C; Serine; Signal Transduction; Tetradecanoylphorbol Acetate

2012
Polymeric black tea polyphenols modulate the localization and activity of 12-O-tetradecanoylphorbol-13-acetate-mediated kinases in mouse skin: mechanisms of their anti-tumor-promoting action.
    Free radical biology & medicine, 2012, Sep-15, Volume: 53, Issue:6

    Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Apoptosis Regulatory Proteins; Camellia sinensis; Carcinogens; Cell Line; Cell Proliferation; Curcumin; Female; Humans; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Plant Extracts; Plant Leaves; Polyphenols; Protein Isoforms; Protein Kinase C; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins c-akt; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Skin; Tetradecanoylphorbol Acetate

2012
Curcumin suppresses the TPA-induced invasion through inhibition of PKCα-dependent MMP-expression in MCF-7 human breast cancer cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Sep-15, Volume: 19, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Breast Neoplasms; Cell Movement; Curcuma; Curcumin; Female; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 9; MCF-7 Cells; Neoplasm Metastasis; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phytotherapy; Plant Extracts; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2012
Anti-inflammatory and apoptotic effects of the polyphenol curcumin on human fibroblast-like synoviocytes.
    International immunopharmacology, 2013, Volume: 15, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arthritis, Rheumatoid; Cell Line; Curcumin; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Interleukin-1beta; Interleukin-6; NF-kappa B; Polyphenols; Synovial Membrane; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A

2013
Curcuminoids distinctly exhibit antioxidant activities and regulate expression of scavenger receptors and heme oxygenase-1.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:9

    Topics: Antioxidants; Biomarkers; CD36 Antigens; Cell Differentiation; Cell Line, Tumor; Copper; Curcumin; Diarylheptanoids; Foam Cells; Gene Expression Regulation; Glutamate-Cysteine Ligase; Heme Oxygenase-1; Humans; Lipid Peroxidation; Lipoproteins, LDL; Monocytes; Scavenger Receptors, Class A; Scavenger Receptors, Class E; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Up-Regulation

2013
Anti-proliferative, anti-inflammatory and antioxidant effects of curcumin analogue A₂.
    Archives of pharmacal research, 2013, Volume: 36, Issue:10

    Topics: Aldehyde Reductase; Animals; Anti-Inflammatory Agents; Antioxidants; Cell Proliferation; Curcumin; Edema; Female; Free Radicals; Interleukin-1beta; Lipid Peroxidation; Male; Mice; NF-kappa B; Tetradecanoylphorbol Acetate

2013
Differential cellular uptake and metabolism of curcuminoids in monocytes/macrophages: regulatory effects on lipid accumulation.
    The British journal of nutrition, 2014, Jul-14, Volume: 112, Issue:1

    Topics: Biological Transport; Carcinogens; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Curcumin; Diarylheptanoids; Glucuronides; Humans; Kinetics; Lipid Metabolism; Macrophages; Monocytes; Sulfates; Tandem Mass Spectrometry; Tetradecanoylphorbol Acetate

2014
Curcumin inhibits EMMPRIN and MMP-9 expression through AMPK-MAPK and PKC signaling in PMA induced macrophages.
    Journal of translational medicine, 2014, Sep-21, Volume: 12

    Topics: Adenylate Kinase; Basigin; Cell Line; Curcumin; Dose-Response Relationship, Drug; Humans; Macrophages; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate

2014
Curcumin relieves TPA-induced Th1 inflammation in K14-VEGF transgenic mice.
    International immunopharmacology, 2015, Volume: 25, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Curcumin; Cytokines; Disease Models, Animal; Gels; Inflammation; Mice, Transgenic; Nuclear Receptor Subfamily 1, Group F, Member 3; Psoriasis; Receptors, Antigen, T-Cell, gamma-delta; Receptors, CCR6; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Th1 Cells

2015
Influence of particle size on the in vitro and in vivo anti-inflammatory and anti-allergic activities of a curcumin lipid nanoemulsion.
    International journal of molecular medicine, 2015, Volume: 35, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Cell Line, Tumor; Curcumin; Drug Carriers; Edema; Emulsions; Macrophages; Male; Mice; Mice, Inbred ICR; Nanoparticles; Particle Size; Rats; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2015
Low dose triterpene-quinone fraction from Ardisia crispa root precludes chemical-induced mouse skin tumor promotion.
    BMC complementary and alternative medicine, 2015, Dec-05, Volume: 15, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Ardisia; Cell Transformation, Neoplastic; Chemical Fractionation; Chemoprevention; Curcumin; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Male; Mice; Mice, Inbred ICR; Plant Extracts; Plant Roots; Quinones; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes

2015
Chemopreventive Agents Attenuate Rapid Inhibition of Gap Junctional Intercellular Communication Induced by Environmental Toxicants.
    Nutrition and cancer, 2016, Volume: 68, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Caprylates; Carcinogens; Cell Communication; Cell Survival; Cells, Cultured; Curcumin; DDT; Epithelial Cells; Fluorenes; Fluorocarbons; Gap Junctions; Hexachlorocyclohexane; Liver; Metformin; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate

2016
MAPKs and NF‑κB pathway inhibitory effect of bisdemethoxycurcumin on phorbol‑12‑myristate‑13‑acetate and A23187‑induced inflammation in human mast cells.
    Molecular medicine reports, 2018, Volume: 17, Issue:1

    Topics: Calcimycin; Cell Line; Curcumin; Diarylheptanoids; Gene Expression Regulation; Humans; Inflammation; Mast Cells; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor RelA

2018
Inhibition of skin tumor promotion by TPA using a combination of topically applied ursolic acid and curcumin.
    Molecular carcinogenesis, 2019, Volume: 58, Issue:2

    Topics: Administration, Topical; Animals; Antineoplastic Combined Chemotherapy Protocols; Chemokine CXCL2; Curcumin; Female; Gene Expression Regulation, Neoplastic; Interleukin-1beta; Interleukin-22; Interleukin-6; Interleukins; Mice; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Treatment Outcome; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays

2019
Inhibitory effects of 7,7'-bromo-curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation.
    European journal of pharmacology, 2019, Sep-05, Volume: 858

    Topics: Animals; Curcumin; Cytokines; Edema; Inflammation; Male; Mice; NF-kappa B; Signal Transduction; Skin; STAT3 Transcription Factor; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

2019
Suppression by Curcuma comosa Roxb. of pro-inflammatory cytokine secretion in phorbol-12-myristate-13-acetate stimulated human mononuclear cells.
    International immunopharmacology, 2007, Volume: 7, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Cell Survival; Curcuma; Diarylheptanoids; Humans; I-kappa B Kinase; Interleukin-1beta; Leukocytes, Mononuclear; NF-kappa B; Plant Extracts; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; U937 Cells

2007
Cancer chemoprotective effects of Curcuma xanthorrhiza.
    Phytotherapy research : PTR, 2008, Volume: 22, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Curcuma; Dose-Response Relationship, Drug; Ear; Edema; Female; Humans; Methanol; Mice; Mice, Inbred ICR; Mutagenesis; Phytotherapy; Plant Extracts; Salmonella typhimurium; Skin Neoplasms; Tetradecanoylphorbol Acetate

2008
Aromatic-turmerone attenuates invasion and expression of MMP-9 and COX-2 through inhibition of NF-κB activation in TPA-induced breast cancer cells.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Chromatin Immunoprecipitation; Curcuma; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Ketones; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; RNA, Small Interfering; Sesquiterpenes; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Transfection

2012
Essential oil from waste leaves of Curcuma longa L. alleviates skin inflammation.
    Inflammopharmacology, 2018, Volume: 26, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Curcuma; Dermatitis; Female; Gas Chromatography-Mass Spectrometry; Humans; Mice; Oils, Volatile; Plant Leaves; Rabbits; Tetradecanoylphorbol Acetate

2018