tetradecanoylphorbol acetate has been researched along with colforsin in 1213 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 220 (18.14) | 18.7374 |
| 1990's | 740 (61.01) | 18.2507 |
| 2000's | 223 (18.38) | 29.6817 |
| 2010's | 30 (2.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Sanders, MM; Skoufos, E | 1 |
| Crook, RB; Yabu, JM | 1 |
| Greer, MA; Sato, N; Wang, X | 1 |
| Koch, B; Lutz-Bucher, B | 3 |
| Alfonso, A; Botana, LM; Botana, MA; Cabado, AG; Louzao, MC; Vieytes, MR | 1 |
| Castrén, E; Hartikka, J; Lindholm, D; Thoenen, H; Zafra, F | 1 |
| Geertsen, S; Quik, M; Trifaro, JM | 1 |
| Bardos, P; Degenne, D; Girard, AC; Guillaumin, JM; Lacord, M; Thibault, G | 1 |
| Holmes, R; Kelly, E; Perez, HD | 1 |
| Nakagawa-Yagi, Y; Nakamura, H; Saito, Y; Takada, Y | 1 |
| Bot, AG; de Jonge, HR; Vaandrager, AB; van den Berghe, N | 1 |
| Fushimi, K; Marumo, F; Nakamura, Y; Sakamoto, H; Sasaki, S | 1 |
| Feldman, D; Krishnan, AV | 1 |
| Kellner, RG; Van der Kraak, G | 1 |
| Morton, ME; Nathanson, NM; Street, VA | 1 |
| Aberdam, E; Aflalo, L; Meidan, R | 1 |
| Heindel, JJ; Treinen, KA | 1 |
| Ashcroft, SJ; Goodison, S; Kenna, S | 1 |
| Gillespie, JI; Greenwell, JR; Johnson, C; Lynch, M | 1 |
| Hattori, M; Horiuchi, R | 1 |
| Hanson, PJ; Keates, AC; Williams, JM | 1 |
| Fujimoto, M; Shigeri, Y | 1 |
| Fang, MA; Hahn, TJ; Kujubu, DA | 1 |
| Bégeot, M; Berthelon, MC; Jaillard, C; Langlois, D; Saez, JM | 1 |
| Iguchi, A; Ishiguro, T; Miura, H; Nonogaki, K; Sakamoto, N; Tamagawa, T; Uemura, K | 1 |
| Koyama, N; Morisaki, N; Saito, Y; Yoshida, S | 1 |
| Albert, PR; Civelli, O; Grandy, DK; Liu, YF | 1 |
| Guerrero, JM; Lopez-Gonzalez, MA; Lucas, M | 1 |
| Brubaker, PL; Stobie-Hayes, KM | 1 |
| Nilsen-Hamilton, M; Thalacker, FW | 1 |
| Bochkov, V; Buhler, F; Resink, T; Tkachuk, V | 1 |
| Handwerger, S; Wu, YQ | 1 |
| Park, D; Rhee, SG | 1 |
| Buchan, KW; Martin, W | 2 |
| Herman, B; Pennybacker, M | 1 |
| Hirota, A | 1 |
| Andrade-Gordon, P; Naftolin, F; Robbins, R; Tranque, P | 1 |
| Angel, P; Karin, M | 1 |
| D'Mello, SR; Heinrich, G; Jiang, C; Lamberti, C; Martin, SC | 1 |
| Hum, DW; Miller, WL; Moore, CC | 1 |
| Frohman, LA; Soszynski, PA | 1 |
| Funakoshi, A; Kitayama, N; Matsuoka, Y; Tateishi, K | 1 |
| Daly, L; Devi, L; Greco, L; Kim, S | 1 |
| Bergonzelli, GE; Kruithof, EK; Medcalf, RL | 1 |
| Emanuel, RL; Girard, DM; Majzoub, JA; Thull, DL | 2 |
| Gespach, C; Hanson, PJ; McKenna, P; Williams, JM | 1 |
| Kerr, DE; Kirkwood, RN; Laarveld, B; Rajkumar, K | 1 |
| Bowyer, JF; Dreyer, E; Houchi, H; Masserano, JS; Nakanishi, A; Sterling, C; Tank, AW; Weiner, N | 1 |
| Min, HK; Park, DJ; Rhee, SG | 1 |
| Barnea, A; Magni, P | 1 |
| Andrews, PE; Montgomery, BT; Tindall, DJ; Young, CY | 1 |
| Richter, J | 1 |
| Eiden, LE; Eskay, RL | 1 |
| Amano, S; Hanazawa, S; Kitami, H; Kitano, S; Murakami, Y; Ohta, K; Takeshita, A | 1 |
| Breuer, W; Cabantchik, ZI; Kartner, N; Riordan, JR | 1 |
| Bradbury, NA; Bridges, RJ | 1 |
| Copolov, DL; Huang, W; Lee, D; Lim, AT; Yang, Z | 1 |
| Correale, J; Link, H; Mix, E; Olsson, T; Solders, G | 1 |
| Aucouturier, S; Bernard, C; Chayvialle, JA; Cuber, JC | 1 |
| Fernandez-Gallardo, S; Guntaka, RV; Kandala, JC; Lim, RW; Shukla, SD; Tripathi, YB | 1 |
| Lalani, S; Mills, GB; Peters, WJ; Sparkes, BG; Teodorczyk-Injeyan, JA | 1 |
| Bressler, JP; Brightman, MW; Tao-Cheng, JH | 1 |
| Rivedal, E; Roseng, LE; Sanner, T | 2 |
| Chang, KJ; Kwon, HB; Lee, CC; Schuetz, AW; Yoo, YR | 1 |
| Akai, H; Finbloom, DS; Hackett, RH; Igarashi, K; Larner, AC; Petricoin, EF | 1 |
| Bennett, MV; Durand, GM; Gregor, P; Uhl, GR; Zheng, X; Zukin, RS | 1 |
| Bajnath, RB; de Jonge, HR; Groot, JA; van Hoeve, MH | 1 |
| Juang, HH; Kapcala, LP; Weng, CF | 1 |
| Babinski, K; De Léan, A; Féthière, J; Ong, H; Roy, M | 1 |
| Arias, R; Barreto, A; Butler, B; Chan, WW; Cheng, K | 1 |
| Geilen, CC; Reutter, W; Wieder, T; Wieprecht, M | 1 |
| Confer, FL; Ferguson, FG; Kariv, I | 1 |
| Hammond, GL; Nelson, PJ; Peyman, JA | 1 |
| Nakamura, M; Niki, M; Ohtani, K; Sugamura, K | 2 |
| Chan, JY; Chan, SH; Fu, MJ; Lin, KS | 1 |
| Cirafici, AM; Colletta, G | 1 |
| Adler, GK; Majzoub, JA; Rosen, LB | 1 |
| Herschman, HR; Kujubu, DA | 1 |
| Wagner, PD; Wu, YN; Yang, YC | 1 |
| Das, B; Fricker, LD; Klein, RS | 1 |
| Capito, K; Hansen, SE; Hedeskov, CJ; Islin, H; Thams, P | 1 |
| Ning, JT; Wornom, IL | 1 |
| Baxter, JD; Schaufele, F; West, BL | 1 |
| Barka, T; Patil, S; van der Noen, H | 1 |
| Printseva, OY; Tjurmin, AV | 1 |
| Asano, K; Iizuka, H; Ito, F; Takahashi, H; Tamura, T; Tsutsui, M | 1 |
| Downs, TR; Frohman, LA | 1 |
| Hershman, JM; Murakami, S; Pang, XP; Sugawara, M; Urabe, M | 1 |
| Nalepa, I; Vetulani, J | 2 |
| Kilfeather, SA; O'Malley, K; Stein, M | 1 |
| Bismuth, G; Debré, P; Feuillard, J; Gouy, H; Körner, M; Lee, LM | 1 |
| Chaudhary, LR; Stocco, DM | 1 |
| Dumont, JE; Pirson, I; Reuse, S | 1 |
| Michelson, S; Paya, CV; Virelizier, JL | 1 |
| Chedrese, PJ; Ly, H; Murphy, BD; Rajkumar, K | 1 |
| D'Mello, SR; Heinrich, G | 1 |
| Barthel, F; Becquet, D; Boudouresque, F; Giraud, P; Grino, M; Kowalski, C; Loeffler, JP; Renard, M | 1 |
| Amiel, C; Friedlander, G; Le Goas, F | 1 |
| Bensussan, A; Bihoreau, C; Corvaïa, N; Degos, L; Enjalbert, A; Heurtier, A; Kordon, C | 1 |
| Calkins, JH; Chang, WW; Lin, T; Nagpal, ML; Wang, D | 1 |
| Barreto, A; Butler, B; Chan, WW; Cheng, K; Smith, RG | 1 |
| Brain, CE; Chomczynski, P; Downs, TR; Frohman, LA | 1 |
| Hadjiconstantinou, M; Moroi-Fetters, SE; Neff, NH; Qu, SZ | 1 |
| Anderson, RJ; Breckon, R | 1 |
| Sung, SS; Walters, JA | 1 |
| Lankford, KL; Letourneau, PC | 1 |
| Ransjö, M | 1 |
| De Pergola, G; Giorgino, R | 1 |
| Harada, K; Ito, H; Nagatsugu, Y; Shingai, R | 1 |
| Izumi, F; Okazaki, M; Terao, T; Uezono, Y; Wada, A; Yanagihara, N | 1 |
| Cugini, CD; Leidy, JW; Millard, WJ | 1 |
| Carroll, JM; Goodman, HM; Joh, TH; Kim, KS; Kim, KT | 1 |
| Johnson, RA; Toews, ML | 1 |
| Zawalich, KC; Zawalich, WS | 2 |
| D'Ambra, R; Efrat, S; Fleischer, N; Starr, RG; Surana, M | 1 |
| Iwashita, S; Mitsui, K; Senshu-Miyaike, M; Shoji-Kasai, Y | 1 |
| Brubaker, PL; Drucker, DJ; Greenberg, GR | 1 |
| Leppäluoto, J; Ruskoaho, H; Vuolteenaho, O | 1 |
| DuBois, RN; Lau, LF; McLane, MW; Nathans, D; Ryder, K | 1 |
| Gullberg, U; Lantz, M; Lindvall, L; Olsson, I | 1 |
| Dorkin, HL; Grubman, SA; Iannuzzi, MC; Jefferson, DM; Klinger, KW; Li, M; Marini, FC; Valentich, JD; Welsh, MJ | 1 |
| Akerblom, IE; Mellon, PL; Ridgway, EC | 1 |
| Malamed, S; Perez, FM; Scanes, CG | 1 |
| Heisler, S | 1 |
| Chou, CF; Omary, MB | 1 |
| Lachowicz, L; Turski, WA | 1 |
| Bosia, A; Bussolino, F; Garbarino, G; Ghigo, D; Heller, R; Pescarmona, G; Schröder, H; Till, U | 1 |
| Defeo-Jones, D; Haskell, KM; Jones, RE; McAvoy, EM; Oliff, A; Vuocolo, GA; Wegrzyn, RJ | 1 |
| Fletcher, BS; Herschman, HR; Kujubu, DA; Lim, RW; Varnum, BC | 1 |
| Budnik, LT; Mukhopadhyay, AK | 2 |
| Cagliero, E; Lorenzi, M; Maiello, M; Roth, T; Roy, S | 1 |
| Brooks, JW; Chedid, M; Mizel, SB; Yoza, BK | 1 |
| Grenfell, S; Ray, K; Rollins, P; Sadler, H; Smithers, N; Solari, R; Thompson, N; Witham, S | 1 |
| Khademazad, M; Loessberg, P; Muallem, S; Whisenant, N; Zhang, BX | 1 |
| Jansen, PL; Ottenhoff, R; Oude Elferink, RP; Roelofsen, H | 1 |
| Anderson, RJ; Breckon, R; Colston, D | 1 |
| Fabbro, D; Knesel, J; Nagamine, Y; Ziegler, A | 1 |
| Asa, SL; Brubaker, PL; Drucker, DJ; Greenberg, GR | 1 |
| Jakubowiak, A; Janecki, A; Steinberger, A | 1 |
| Donoghue, DJ; Scanes, CG | 1 |
| Ahrén, B; Lindskog, S | 1 |
| Carroll, JM; Evinger, MJ; Goodman, HM; Joh, TH | 1 |
| Biswas, S; Hu, SB; Lightman, SL; Tannahill, LA | 1 |
| Eiden, LE; Grimes, M; Iacangelo, AL | 1 |
| Grauer, A; Lazaretti-Castro, M; Mekonnen, Y; Raue, F; Ziegler, R | 1 |
| Beil, W; Bersimbaev, R; Sewing, KF | 1 |
| Dasgupta, JD; Granja, C; Lin, LL; Relias, V; Yunis, EJ | 1 |
| Ashcroft, SJ; Niki, I | 1 |
| Koyasu, S; Sugie, K; Tagaya, Y; Yahara, I; Yodoi, J; Yonehara, S | 1 |
| Leib, DA; Nadeau, KC; Rundle, SA; Schaffer, PA | 1 |
| Kasayama, S; Kouhara, H; Matsumoto, K; Saito, H; Sato, B | 1 |
| Ishikawa, S; Saito, T | 1 |
| Chik, CL; Ho, AK | 1 |
| Akimoto, Y; Endo, H; Hirano, H; Obinata, A | 1 |
| Fink, JS; Goodman, RH; Mandel, G; Verhave, M; Walton, K | 1 |
| Bonin, H; Bouvier, M; Guilbault, N | 1 |
| Fischer, JA; Kaufmann, M; Muff, R | 1 |
| Curry, TE; Edwards, DR; Kindy, MS; Mann, JS | 1 |
| Chew, CS; Petropoulos, AC | 1 |
| Harris, RC; Homma, T | 1 |
| Birnbaumer, M; Clark, RB; Friedman, J; Halligan, RD; Johnson, JA | 1 |
| Heldin, CH; Miyazono, K; Usuki, K | 1 |
| Chiu, R; Karin, M; Yang-Yen, HF | 1 |
| Iizuka, H; Tsutsui, M | 1 |
| Kream, BE; Petersen, DN; Raisz, LG | 1 |
| Koteliansky, VE; Lukashev, ME; Spangenberg, P; Till, U | 1 |
| Brentano, ST; Mellon, SH; Miller, WL; Moore, CC; Picado-Leonard, J | 1 |
| Bertrand, F; Capeau, J; Cherqui, G; Garcia, I; Hermelin, B; Paul, A; Picard, J | 1 |
| Korichneva, IL; Tkachuk, VA | 1 |
| Bowyer, JF; Houchi, H; Masserano, JM; Weiner, N | 1 |
| Davis, SK; French, JT; McArthur, NH; Tanner, JW; Welsh, TH | 1 |
| Buchan, AM; Campos, RV; Coy, DH; Kwok, YN; Meloche, RM; Pederson, RA | 1 |
| Buchan, AM; Curtis, SB; Meloche, RM | 1 |
| Chomczynski, P; Downs, TR; Frohman, LA; Kashio, Y | 1 |
| Davis, LS; Lipsky, PE; Minakuchi, R; Wacholtz, MC | 1 |
| Bedoya, FJ; Jeanrenaud, B | 1 |
| Banks, TC; Bargon, J; Chu, CS; Dalemans, W; Guggino, WB; Nakamura, H; Pavirani, A; Trapnell, BC; Yoshimura, K; Zeitlin, PL | 1 |
| Agoston, DV; Bravo, DT; Waschek, JA | 1 |
| Crowley, WR; Grosvenor, CE; Shah, GV; Wang, W | 1 |
| Mori, T; Murata, A; Ogawa, M; Oka, Y; Uda, K; Yasuda, T | 1 |
| de Boland, AR; Norman, AW | 1 |
| Bellard, M; Chambon, P; Gaub, MP; Sassone-Corsi, P; Scheuer, I | 1 |
| Hertz, E; Hertz, L; Nelson, DJ; Soliven, B; Szuchet, S | 1 |
| Kajiyama, Y; Murayama, T; Nomura, Y; Takahashi, A | 1 |
| Aas, AT; Blomhoff, HK; Ludt, J; Olsnes, S; Tønnessen, TI | 1 |
| Bilezikjian, LM; Corrigan, AZ; Vale, W | 1 |
| Pasqualini, JR; Sumida, C | 1 |
| Hurme, M | 1 |
| Dickinson, KE; Hirschowitz, BI; Horiguchi, Y; Matsumoto, H; Uemura, N | 1 |
| Higuchi, H; Sabol, SL | 1 |
| Dumont, JE; Maenhaut, C; Reuse, S | 1 |
| Jarvis, WD; Judd, AM; Kuan, SI; Kubota, T; Macleod, RM; Spangelo, BL | 1 |
| Nicholson, WE; Oki, Y; Orth, DN | 1 |
| de Boland, AR; Norman, A | 1 |
| Huhtaniemi, I; Nikula, H; Vihko, K | 1 |
| Flaegstad, T; Moens, U; Sundsfjord, A; Traavik, T | 1 |
| diZerega, GS; Hylka, VW | 1 |
| Goetz, FW; Ranjan, M | 1 |
| Agrawal, D; Agrawal, HC; Sprinkle, TJ | 2 |
| Endou, H; Satoh, T | 1 |
| Patke, CL; Shearer, WT | 1 |
| Hornsby, PJ; Naseeruddin, SA | 1 |
| Clark, RB; Dixon, RA; Friedman, J; Johnson, JA; Strader, CD | 1 |
| Ishimura, Y; Kizaki, H; Suzuki, K; Tadakuma, T | 1 |
| Bonin, PD; Chiou, WJ; McGee, JE; Singh, JP | 1 |
| Cho, WK; Kim, K; Lee, BJ | 1 |
| Helmle-Kolb, C; Montrose, MH; Murer, H | 1 |
| Novak, TJ; Rothenberg, EV | 1 |
| Hurme, M; Ronni, T; Serkkola, E; Silvennoinen, O | 1 |
| Bankhurst, AD; Whalen, MM | 1 |
| Chedrese, PJ; Juorio, AV; Labrie, F; Luu The, V; Murphy, BD; Zhang, D | 1 |
| Burstein, DE; Lacal, JC; Pellicer, A; Thomson, TM; Trotta, RJ | 1 |
| Larsson, R; Nygren, P | 1 |
| Chedid, M; Mizel, SB | 1 |
| Abrahamsen, MS; Morris, DR | 1 |
| Dupont, MA; Gas, N; Guilbaud, NF; Valette, A | 1 |
| Hesketh, R; Metcalfe, JC; Moore, TA; Pennington, SR; Smith, GA | 1 |
| Baxter, JD; Duncan, KG; Haidar, MA; Reudelhuber, TL | 1 |
| Brunswig-Spickenheier, B; Mukhopadhyay, AK | 1 |
| LaForge, KS; Ray, A; Sehgal, PB | 1 |
| Aakvaag, A; Lahooti, H; Thorsen, T | 1 |
| Scholz, W | 1 |
| Akerman, KE; Heikkilä, JE | 1 |
| Gobran, LI; Rooney, SA | 1 |
| Selak, MA; Smith, JB | 1 |
| Abruzzese, RV; Cote, GJ; Gagel, RF; Lips, CJ | 1 |
| Chan, EC; Davies, J; Falconer, J; Geraghty, S; Madsen, G; Smith, R; Thomson, M | 1 |
| Boutterin, MC; Doye, V; Sobel, A | 1 |
| Classen, M; Håkanson, R; Prinz, C; Schepp, W; Schusdziarra, V | 1 |
| Buckner, CK; Graziano, FM; Undem, BJ | 1 |
| Forder, J; Rasmussen, H; Scriabine, A | 1 |
| Axelrod, J; Corda, D; Guild, S; Lewis, D; Luini, A | 1 |
| Park, S; Rasmussen, H | 1 |
| Assayag, E; Heisler, S; Labrie, F; Mehri, Y; Simard, J | 1 |
| Eckhardt, L; Imamura, K; Kimura, T; Schulz, I | 1 |
| Danoff, A; Fleischer, N; Pasmantier, R; Schubart, UK | 1 |
| Blackmore, PF; Exton, JH | 1 |
| Ganten, D; Lang, RE; Ruskoaho, H; Toth, M; Unger, T | 1 |
| Campagnoni, AT; Dawson, G; Szuchet, S; Vartanian, T | 1 |
| Ishitoya, J; Takenawa, T | 1 |
| Cuttitta, F; Giraud, AS; Soll, AH; Walsh, JH | 1 |
| Niki, A; Niki, H; Niki, I; Tamagawa, T | 1 |
| Dickinson, KE; Hirschowitz, BI; Komiyama, K; Matsumoto, H; Shirakawa, T | 1 |
| Haslam, RJ; Murphy, W; Williams, KA | 1 |
| Kleeman, CR; Muallem, S; Yamaguchi, DT | 1 |
| Kagawa, S; Matsuoka, A; Nakao, K; Wakabayashi, S | 1 |
| Klein, DC; Sugden, D | 1 |
| Sitkovsky, MV; Takayama, H; Trenn, G | 1 |
| Dieguez, C; Edwards, CA; Ham, J; Peters, JR; Scanlon, MF | 1 |
| Rink, TJ; Sage, SO | 1 |
| Bolaffi, JL; Bruno, L; Grodsky, GM; Heldt, A | 1 |
| Gilman, MZ | 1 |
| Emoto, T; Hiraiwa, M; Kasai, K; Shimoda, S | 1 |
| Barron, KS; Gilliam, EB; Orson, FM; Patke, CL; Rosenblatt, HM; Shearer, WT | 1 |
| Blomhoff, HK; Funderud, S; Holte, H; Ruud, E; Smeland, EB; Torjesen, P | 1 |
| Goto, Y; Sugamura, K; Takeshita, T | 1 |
| Levin, EG; Santell, L | 1 |
| Iida, H; Page, E | 1 |
| Hu, JS; Olson, EN | 1 |
| Bauer, K; Hamprecht, B; Kleinkauf, H; Schulz, M | 1 |
| Ray, KP; Wallis, M | 1 |
| Goldman, JE; Kume-Iwaki, A; Shafit-Zagardo, B | 1 |
| Baru, M; Manor, H | 1 |
| LaMontagne, AD; Petito, CT; Rice, RH; Rong, XH | 1 |
| Soll, AH; Toomey, M | 1 |
| Buchou, T; Charollais, RH; Fagot, D; Mester, J | 1 |
| Bertrand, G; Henquin, JC; Nenquin, M | 1 |
| Borst, SE; Catherwood, BD | 1 |
| Dawson, G; McAtee, P | 2 |
| Bolanowski, MA; Bouvier, M; Caron, MG; Collins, S; Lefkowitz, RJ | 1 |
| Copp, RP; Samuels, HH | 1 |
| Heisler, S; Jeandel, L | 1 |
| Hagiwara, N; Irisawa, H | 1 |
| Endou, H; Miyanoshita, A; Takahashi, T | 1 |
| Birnbaum, MJ; Hiraki, Y; McMorrow, IM | 1 |
| Bala, RM; Eatock, BA; Sheppard, MS | 1 |
| Lüscher, B; Mitchell, PJ; Tjian, R; Williams, T | 1 |
| Danowski, BA | 1 |
| Brzozowski, T; Cherner, JA; Naik, L; Singh, G; Stachura, J; Tarnawski, A | 1 |
| Seidler, U; Sewing, KF | 1 |
| Levin, EG; Marotti, KR; Santell, L | 1 |
| Murray, TM; Rao, LG | 1 |
| Barber, DL; Buchan, AM; Leeman, SE; Soll, AH | 1 |
| Baes, M; Vale, WW | 1 |
| Getz, GS; Larsen, AL; Schreiber, JR; Wyne, KL | 1 |
| Ito, Y; Satake, M; Yamaguchi, Y | 1 |
| diZerega, GS; Hylka, VW; Kaki, MK | 1 |
| Cabot, MC; Cao, HT; Welsh, CJ; Zhang, ZC | 1 |
| Scarpa, A; Wiener, E | 1 |
| Axelrod, J; Eskay, R; Făgăraşan, MO | 1 |
| Sehgal, PB; Tamm, I; Yan, C | 1 |
| Henry, HL; Luntao, EM | 1 |
| Imamoto, F; Imura, H; Ishii, S; Seino, Y; Takeda, J | 1 |
| Miller, RJ; Perney, TM | 1 |
| Asem, EK; Tsang, BK | 1 |
| Benezra, M; Gerst, JE; Salomon, Y; Schimmer, A | 1 |
| Counis, R; Jutisz, M; Starzec, A | 1 |
| Kawamoto, F; Kojima, K; Kumada, N; Shozawa, A | 1 |
| Avdonin, PV; Svitina-Ulitina, IV; Tkachuk, VA | 1 |
| Antonov, AS; Antonova, GN; Kabaeva, NV; Lukashev, ME; Romanov, YA; Smirnov, VN; Tchertikhina, IV | 1 |
| Aizawa, T; Nozawa, A; Yoshikawa, K | 1 |
| Chik, CL; Ho, AK; Klein, DC | 1 |
| Hornsby, PJ | 1 |
| Murer, H; Pfeilschifter, J; Quamme, G | 1 |
| Durston, AJ; Heideveld, M; Otte, AP; van Driel, R; van Run, P | 1 |
| Iizuka, H; Sakai, H; Tamura, T | 1 |
| Castro, MG; Gusovsky, F; Loh, YP | 1 |
| Veldhuis, JD; Wheeler, MB | 2 |
| Findlay, DM; Michelangeli, VP; Robinson, PJ | 1 |
| Arcone, R; Ciliberto, G; Ganter, U; Morrone, G; Toniatti, C | 1 |
| García-Sáinz, JA; Gutiérrez-Venegas, G | 1 |
| Casavola, V; Helmle-Kolb, C; Murer, H | 1 |
| Fujita, T; Kimura, Y; Reis, LF; Taniguchi, T; Vilcek, J; Watanabe, N | 1 |
| Biber, J; Murer, H; Quamme, G | 1 |
| Aasheim, LH; Franks, DJ; Kleine, LP | 1 |
| Björo, T; Gautvik, KM; Gordeladze, JO; Haug, E; Ostberg, BC; Torjesen, PA | 1 |
| Estival, A; Lherisson, C; Pradayrol, L; Vaysse, N | 1 |
| Ashcroft, SJ; Chalk, JG; Hughes, SJ | 1 |
| Henquin, JC; Mourmeaux, JL; Remacle, C | 1 |
| Banga, JP; Barnett, PS; Collison, KS; Kung, AW; McGregor, AM | 1 |
| Broadus, AE; Deftos, LJ; Gazdar, AF; Ikeda, K | 1 |
| Dettmer, D; Hermsdorf, T; Hofmann, E | 1 |
| Black, EG; Docherty, K; Phillips, ID; Sheppard, MC | 1 |
| Bunn, SJ; Livett, BG; Wan, DC | 1 |
| Davis, JR; Johnson, AP; Lynch, SS; Sheppard, MC; Vidal, ME; Wilson, EM | 1 |
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1 review(s) available for tetradecanoylphorbol acetate and colforsin
| Article | Year |
|---|---|
Regulation of VIP gene expression in general. Human lung cancer cells in particular.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Colforsin; Cyclic AMP; Dactinomycin; Female; Gene Expression Regulation; Humans; Lung Neoplasms; Male; Neoplasm Proteins; Neurosecretory Systems; Nucleic Acid Synthesis Inhibitors; Organ Specificity; Rats; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1996 |
1212 other study(ies) available for tetradecanoylphorbol acetate and colforsin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Regulation of expression of the chicken ovalbumin gene: interactions between steroid hormones and second messenger systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Chickens; Colforsin; Corticosterone; Drug Interactions; Estrogens; Female; Gene Expression Regulation; Insulin; Ovalbumin; Oviducts; Protein Kinase C; Protein Kinases; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1992 |
Calcitonin gene-related peptide stimulates intracellular cAMP via a protein kinase C-controlled mechanism in human ocular ciliary epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Calcitonin; Calcitonin Gene-Related Peptide; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Epithelium; Eye; Fetus; Humans; Kinetics; Phorbol Esters; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Lidocaine inhibits prolactin secretion in GH4C1 cells by blocking calcium influx.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenoma; Animals; Calcium; Colforsin; Lidocaine; Pituitary Neoplasms; Potassium; Procaine; Prolactin; Rats; Tetradecanoylphorbol Acetate; Tetrodotoxin; Tumor Cells, Cultured | 1992 |
Pituitary adenylate cyclase polypeptide (PACAP) stimulates cyclic AMP formation in pituitary fibroblasts and 3T3 tumor fibroblasts: lack of enhancement by protein kinase C activation.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Adenylate Cyclase Toxin; Animals; Cell Line, Transformed; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Enzyme Activation; Fibroblasts; Male; Mice; Neuropeptides; Pertussis Toxin; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Protein Kinase C; Rats; Rats, Wistar; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1992 |
Influence of protein kinase C, cAMP and phosphatase activity on histamine release produced by compound 48/80 and sodium fluoride on rat mast cells.
Topics: Animals; Colforsin; Cyclic AMP; Enzyme Activation; Ethers, Cyclic; Histamine Release; In Vitro Techniques; Mast Cells; Okadaic Acid; p-Methoxy-N-methylphenethylamine; Phosphodiesterase Inhibitors; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rolipram; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1992 |
Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Glutamates; Glutamic Acid; Growth Substances; Hippocampus; Ionomycin; Isoquinolines; Kainic Acid; Kinetics; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Nifedipine; Norepinephrine; Piperazines; Potassium; Protein Kinase Inhibitors; Quisqualic Acid; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Phorbol esters and K+ up-regulate alpha-bungarotoxin binding sites in cultured chromaffin cells through a related mechanism.
Topics: Adrenal Medulla; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Cattle; Cells, Cultured; Colforsin; DNA-Binding Proteins; Enzyme Activation; Kinetics; Polymyxin B; Potassium; Protein Kinase C; Receptors, Nicotinic; Tetradecanoylphorbol Acetate; Up-Regulation | 1992 |
Inhibitory effect of human syncytiotrophoblast plasma membrane vesicles on Jurkat cells activated by phorbol ester and calcium ionophore.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcimycin; Calcium; CD3 Complex; Cell Membrane; Colforsin; Cyclic AMP; Cytoplasm; Down-Regulation; Female; Humans; Interleukin-2; Lymphocyte Activation; Pregnancy; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate; Trophoblasts; Tumor Cells, Cultured | 1992 |
Regulation of formyl peptide receptor expression and its mRNA levels during differentiation of HL-60 cells.
Topics: Alkaloids; Binding Sites; Bucladesine; Cell Differentiation; Chromatography, Liquid; Colforsin; Dexamethasone; Drug Antagonism; Gene Expression Regulation; Humans; Protein Kinase C; Protein Kinases; Receptors, Formyl Peptide; Receptors, Immunologic; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured; Up-Regulation | 1992 |
Suppressive effect of carbachol on forskolin-stimulated neurite outgrowth in human neuroblastoma NB-OK1 cells.
Topics: Atropine; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Colforsin; Cyclic AMP; Drug Interactions; Egtazic Acid; Gallic Acid; Humans; Inositol; Inositol Phosphates; Kinetics; Neurites; Neuroblastoma; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1992 |
Phorbol esters stimulate and inhibit Cl- secretion by different mechanisms in a colonic cell line.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bumetanide; Calcimycin; Cell Line; Chlorides; Colforsin; Colon; Cyclic AMP; Iodides; Potassium; Rubidium; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Regulation of endothelin-1 production in cultured rat mesangial cells.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Endothelins; Enzyme Activation; Glomerular Mesangium; Isoquinolines; Mitosis; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1992 |
Cyclic adenosine 3',5'-monophosphate up-regulates 1,25-dihydroxyvitamin D3 receptor gene expression and enhances hormone action.
Topics: 3T3 Cells; Animals; Blotting, Northern; Calcitriol; Cell Division; Colforsin; Cyclic AMP; Gene Expression Regulation; Mice; Protein Kinase C; Protein Kinases; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; Tetradecanoylphorbol Acetate; Up-Regulation | 1992 |
Multifactorial regulation of prostaglandin synthesis in preovulatory goldfish ovarian follicles.
Topics: Animals; Bucladesine; Calcimycin; Chloroquine; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Female; Goldfish; Melitten; Ovarian Follicle; Ovary; Phospholipases A; Phospholipases A2; Prostaglandins; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Selective regulation of Gi alpha 1 expression and function in PC12 cells by cAMP.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Gene Expression Regulation; GTP-Binding Proteins; Half-Life; Nerve Growth Factors; Neurons; Nucleic Acid Hybridization; PC12 Cells; Phenylisopropyladenosine; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Steroidogenic enzyme content and progesterone induction by cyclic adenosine 3',5'-monophosphate-generating agents and prostaglandin F2 alpha in bovine theca and granulosa cells luteinized in vitro.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprost; Female; Granulosa Cells; Insulin; Luteinizing Hormone; Progesterone; Steroids; Tetradecanoylphorbol Acetate; Theca Cells | 1992 |
Evidence that MEHP inhibits rat granulosa cell function by a protein kinase C-independent mechanism.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diethylhexyl Phthalate; Female; Follicle Stimulating Hormone; Granulosa Cells; Isoproterenol; Progesterone; Protein Kinase C; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate | 1992 |
Control of insulin gene expression by glucose.
Topics: Alkaloids; Blotting, Northern; Bucladesine; Cell Line; Chimera; Chloramphenicol O-Acetyltransferase; Colforsin; Enhancer Elements, Genetic; Gene Expression Regulation; Glucose; Insulin; Islets of Langerhans; Proinsulin; Promoter Regions, Genetic; Protein Kinase C; Protein Kinases; Protein Precursors; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transfection; Verapamil | 1992 |
Actions of the phorbol ester, PMA, on ATP-induced fluctuations in cytoplasmic calcium in single isolated bovine aortic endothelial cells.
Topics: Adenosine Triphosphate; Animals; Aorta; Bucladesine; Calcium; Cattle; Cell Separation; Colforsin; Cytoplasm; Endothelium, Vascular; Osmolar Concentration; Tetradecanoylphorbol Acetate | 1992 |
Enhancement of ganglioside GM3 synthesis in okadaic-acid-treated granulosa cells.
Topics: Animals; Carbohydrate Sequence; Chorionic Gonadotropin; Chromatography, Thin Layer; Colforsin; Cyclic AMP; Down-Regulation; Ethers, Cyclic; Female; Follicle Stimulating Hormone; G(M3) Ganglioside; Granulosa Cells; Molecular Sequence Data; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; Receptors, LH; Tetradecanoylphorbol Acetate | 1992 |
Activation of intracellular signalling pathways induces secretion of mucin by isolated rat gastric mucosal cells.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Gastric Mucosa; Kinetics; Mucins; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Two different signal transductions of neuropeptide Y1 receptor in SK-N-MC cells.
Topics: Alkaloids; Calcium; Colforsin; Cyclic AMP; Diglycerides; Humans; In Vitro Techniques; Neuropeptide Y; Pertussis Toxin; Receptors, Neuropeptide Y; Second Messenger Systems; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
The effects of prostaglandin E2, parathyroid hormone, and epidermal growth factor on mitogenesis, signaling, and primary response genes in UMR 106-01 osteoblast-like cells.
Topics: Animals; Bone Neoplasms; Calcium; Colforsin; Cyclic AMP; Cycloheximide; Dinoprostone; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Immediate-Early Proteins; Inositol Phosphates; Mitosis; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinases; Radioimmunoassay; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thymidine; Transcription Factors; Tritium; Tumor Cells, Cultured; Zinc Fingers | 1992 |
Angiotensin II potentiates agonist-induced 3',5'-cyclic adenosine monophosphate production by cultured bovine adrenal cells through protein kinase C and calmodulin pathways.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alkaloids; Angiotensin II; Animals; Calcium Channels; Calmodulin; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; GTP-Binding Proteins; Hydrocortisone; Nifedipine; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Trifluoperazine | 1992 |
Effects of the protein phosphatase inhibitors okadaic acid and calyculin A on insulin release from rat pancreatic islets.
Topics: Animals; Colforsin; Dose-Response Relationship, Drug; Ethers, Cyclic; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Potassium; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1992 |
Regulatory effects of platelet-derived growth factor-AA homodimer on migration of vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Aorta, Thoracic; Biological Factors; Bucladesine; Cell Division; Cell Movement; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Fibronectins; Isoquinolines; Kinetics; Macromolecular Substances; Muscle, Smooth, Vascular; Pertussis Toxin; Piperazines; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Wistar; Recombinant Proteins; Second Messenger Systems; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Virulence Factors, Bordetella | 1992 |
Differential sensitivity of the short and long human dopamine D2 receptor subtypes to protein kinase C.
Topics: Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Dopamine; Enzyme Activation; Fibroblasts; Mice; Pertussis Toxin; Protein Kinase C; Receptors, Dopamine D2; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1992 |
Vasoactive intestinal peptide enhances phorbol myristate acetate-induced chemiluminescence in human lymphocytes.
Topics: Adenylyl Cyclases; Colforsin; Concanavalin A; Cyclic AMP; Drug Synergism; Humans; Luminescent Measurements; Lymphocytes; Monocytes; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1992 |
Control of proglucagon-derived peptide synthesis and secretion in fetal rat hypothalamus.
Topics: Animals; Bucladesine; Cells, Cultured; Colforsin; Enzyme Activation; Fetal Proteins; Glucagon; Hypothalamus; Neuropeptides; Proglucagon; Protein Kinase C; Protein Kinases; Protein Precursors; Radioimmunoassay; Rats; Tetradecanoylphorbol Acetate | 1992 |
Opposite and independent actions of cyclic AMP and transforming growth factor beta in the regulation of type 1 plasminogen activator inhibitor expression.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Down-Regulation; Epithelial Cells; Epithelium; Fibroblasts; Gene Expression Regulation; Haplorhini; Humans; Mink; Plasminogen Activator Inhibitor 1; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta; Virulence Factors, Bordetella | 1992 |
Phosphoinositide and calcium signalling responses in smooth muscle cells: comparison between lipoproteins, Ang II, and PDGF.
Topics: Angiotensin II; Calcium; Colforsin; Cyclic GMP; Cytosol; Humans; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Muscle, Smooth, Vascular; Phosphatidylinositols; Platelet-Derived Growth Factor; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1992 |
High density lipoproteins stimulate molecular weight 80K protein phosphorylation in human trophoblast cells: evidence for a protein kinase-C-dependent pathway in human placental lactogen release.
Topics: Apolipoprotein A-I; Bucladesine; Cells, Cultured; Colforsin; Enzyme Activation; Female; Humans; Lipoproteins, HDL; Molecular Weight; Phosphoproteins; Phosphorylation; Placenta; Placental Lactogen; Pregnancy; Protein Kinase C; Tetradecanoylphorbol Acetate; Trophoblasts | 1992 |
Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Cell Line; Chromatography, Affinity; Colforsin; Cyclic AMP; Epidermal Growth Factor; Immunoblotting; Kinetics; Molecular Sequence Data; Oncogene Proteins; Organ Specificity; PC12 Cells; Phosphorylation; Precipitin Tests; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Serine; Tetradecanoylphorbol Acetate; Threonine; Type C Phospholipases | 1992 |
Modulation of barrier function of bovine aortic and pulmonary artery endothelial cells: dissociation from cytosolic calcium content.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Calcium; Capillary Permeability; Cattle; Colforsin; Cyclic GMP; Cytosol; Endothelium, Vascular; Peptide Fragments; Pulmonary Artery; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Transforming growth factor-beta (TGF-b) induced phosphorylation of the myristoylated alanine rich C kinase substrate (MARCKS) protein in ovarian granulosa cells is modulated by follicle stimulating hormone (FSH).
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Female; Follicle Stimulating Hormone; Granulosa Cells; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1992 |
[Modulation of the adenylate cyclase-cAMP pathway by protein kinase C in chick retinal pigment epithelium].
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Isoproterenol; Pigment Epithelium of Eye; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Regulation of plasminogen activators and type-1 plasminogen activator inhibitor by cyclic AMP and phorbol ester in rat astrocytes.
Topics: Animals; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Intracellular Membranes; Molecular Conformation; Plasminogen Activator Inhibitor 1; Rats; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 1992 |
Specific members of the Jun protein family regulate collagenase expression in response to various extracellular stimuli.
Topics: Colforsin; Collagenases; Cyclic AMP; DNA, Neoplasm; Enzyme Induction; Gene Expression Regulation; Genes, fos; Genes, jun; Humans; Neoplasm Proteins; Promoter Regions, Genetic; Protein Multimerization; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tumor Cells, Cultured | 1992 |
Differential regulation of the nerve growth factor and brain-derived neurotrophic factor genes in L929 mouse fibroblasts.
Topics: Animals; Base Sequence; Blotting, Northern; Brain-Derived Neurotrophic Factor; Colforsin; Corticosterone; Cyclic AMP; Fibroblasts; Gene Expression Regulation; Hippocampus; Kainic Acid; L Cells; Male; Mice; Molecular Sequence Data; Nerve Growth Factors; Nerve Tissue Proteins; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Tetradecanoylphorbol Acetate | 1992 |
Identification of positive and negative placenta-specific basal elements and a cyclic adenosine 3',5'-monophosphate response element in the human gene for P450scc.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Base Sequence; Calcimycin; Cholesterol Side-Chain Cleavage Enzyme; Choriocarcinoma; Colforsin; Cyclic AMP; Cycloheximide; DNA; Ethanol; Female; Gene Expression Regulation, Enzymologic; Genes; Humans; Molecular Sequence Data; Organ Specificity; Placenta; Pregnancy Proteins; Promoter Regions, Genetic; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Uterine Neoplasms | 1992 |
Interaction of ethanol with signal transduction mechanisms mediating growth hormone release by rat pituitary cells in vitro.
Topics: Animals; Bucladesine; Calcimycin; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Ethanol; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; RNA, Messenger; Signal Transduction; Somatostatin; Tetradecanoylphorbol Acetate | 1992 |
Interaction between phosphoinositide turnover system and cyclic AMP pathway for the secretion of pancreastatin and somatostatin from QGP-1N cells.
Topics: Adenoma, Islet Cell; Atropine; Bucladesine; Calcimycin; Carbachol; Cell Line; Chromogranin A; Colforsin; Cyclic AMP; Drug Synergism; Humans; Kinetics; Pancreatic Hormones; Pancreatic Neoplasms; Phosphatidylinositols; Somatostatin; Tetradecanoylphorbol Acetate; Theophylline; Tumor Cells, Cultured | 1992 |
Dynorphin-processing endopeptidase in the rat anterior pituitary lactotrophic cell line, GH4C1.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Line; Chromatography, High Pressure Liquid; Colforsin; Dynorphins; Endopeptidases; Endorphins; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Pituitary Gland, Anterior; Potassium Chloride; Prolactin; Protease Inhibitors; Rats; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1992 |
Transcriptional antagonism of phorbol ester-mediated induction of plasminogen activator inhibitor types 1 and 2 by cyclic adenosine 3',5'-monophosphate.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Line; Cell Nucleus; Colforsin; Cyclic AMP; DNA Probes; Fibrosarcoma; Gene Expression; Humans; Kinetics; Plasminogen Inactivators; Poly A; Protein Kinase C; Protein Kinases; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic | 1992 |
Regulated expression of vasopressin gene by cAMP and phorbol ester in primary rat fetal hypothalamic cultures.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; Gene Expression Regulation; Hypothalamus; Poly A; Potassium; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Vasopressins | 1992 |
Protein kinase C inhibits histamine H2 receptor-mediated stimulation of cyclic AMP content in the human gastric cancer cell line HGT-1.
Topics: Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Histamine; Histamine H2 Antagonists; Humans; Protein Kinase C; Receptors, Histamine H2; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Inhibitory action of somatostatin-14 on hormone-stimulated cyclic adenosine monophosphate induction in porcine granulosa and luteal cells.
Topics: Animals; Cells, Cultured; Colforsin; Corpus Luteum; Cyclic AMP; Dose-Response Relationship, Drug; Female; Granulosa Cells; Luteinizing Hormone; Pituitary Gland; Protein Kinase C; Somatostatin; Stimulation, Chemical; Swine; Tetradecanoylphorbol Acetate | 1992 |
Phosphorylation and activation of tyrosine hydroxylase in PC18 cells: a cell line derived from rat pheochromocytoma PC12 cells.
Topics: Animals; Bucladesine; Calcimycin; Colforsin; Cyclic AMP; Dexamethasone; Enzyme Activation; PC12 Cells; Peptide Mapping; Phosphorylation; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1992 |
Inhibition of CD3-linked phospholipase C by phorbol ester and by cAMP is associated with decreased phosphotyrosine and increased phosphoserine contents of PLC-gamma 1.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Kinetics; Muromonab-CD3; Peptide Mapping; Phosphates; Phosphopeptides; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate; Trypsin; Type C Phospholipases; Tyrosine | 1992 |
Forskolin and phorbol ester stimulation of neuropeptide Y (NPY) production and secretion by aggregating fetal brain cells in culture: evidence for regulation of NPY biosynthesis at transcriptional and posttranscriptional levels.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Brain; Cell Aggregation; Cells, Cultured; Colforsin; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Fetus; Hypothalamus; Kinetics; Neuropeptide Y; Olfactory Bulb; Protein Biosynthesis; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Transcription, Genetic; Verapamil | 1992 |
Tumor-promoting phorbol ester down-regulates the androgen induction of prostate-specific antigen in a human prostatic adenocarcinoma cell line.
Topics: Alkaloids; Antigens, Neoplasm; Biomarkers, Tumor; Calcimycin; Colforsin; Dose-Response Relationship, Drug; Down-Regulation; Humans; Male; Nandrolone; Phorbols; Prostate-Specific Antigen; Prostatic Neoplasms; RNA, Messenger; Staurosporine; Testosterone Congeners; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF-, and chemotactic peptide-induced degranulation in single adherent neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Blood Proteins; Bucladesine; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Colforsin; Cyclic AMP; Cytochalasin B; Exocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Interleukin-1 alpha and tumor necrosis factor-alpha differentially regulate enkephalin, vasoactive intestinal polypeptide, neurotensin, and substance P biosynthesis in chromaffin cells.
Topics: Animals; Cattle; Cells, Cultured; Chromaffin Granules; Colforsin; Enkephalin, Methionine; Interleukin-1; Interleukin-2; Neurotensin; Substance P; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide | 1992 |
Porphyromonas gingivalis fimbriae induce expression of the neutrophil chemotactic factor KC gene of mouse peritoneal macrophages: role of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Bucladesine; Chemotaxis, Leukocyte; Colforsin; Dose-Response Relationship, Drug; Fimbriae, Bacterial; Gene Expression Regulation, Bacterial; Interleukin-8; Isoquinolines; Macrophages; Mice; Mice, Inbred BALB C; Neutrophils; Piperazines; Porphyromonas gingivalis; Protein Kinase C; RNA; Sulfonamides; Tetradecanoylphorbol Acetate | 1992 |
Induction of expression of the cystic fibrosis transmembrane conductance regulator.
Topics: Adenocarcinoma; Amanitins; Blotting, Western; Chlorides; Colforsin; Cyclic AMP; Cycloheximide; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dactinomycin; DNA; Humans; Membrane Proteins; Promoter Regions, Genetic; Protein Biosynthesis; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 1992 |
Endocytosis is regulated by protein kinase A, but not protein kinase C in a secretory epithelial cell line.
Topics: Alkaloids; Animals; Calcium; Cell Line; Chlorides; Colforsin; Cyclic AMP; Dextrans; Diglycerides; Endocytosis; Epithelium; Fluorescein-5-isothiocyanate; Homeostasis; Horseradish Peroxidase; Kinetics; Protein Kinase C; Protein Kinases; Second Messenger Systems; Staurosporine; Temperature; Tetradecanoylphorbol Acetate | 1992 |
In vitro evidence for modulation of morphological and functional development of hypothalamic immunoreactive atrial natriuretic peptide neurons by cyclic 3',5'-adenosine monophosphate.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Cell Count; Colforsin; Colorimetry; Fluorescent Antibody Technique; Hypothalamus; Neurons; Oligonucleotide Probes; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Effect of stilbene-type anion channel blockers on the immune response during experimental allergic neuritis (EAN).
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Autoimmunity; Colforsin; Interferon-gamma; Ion Channel Gating; Ion Channels; Ionomycin; Lymphocyte Activation; Neural Conduction; Neuritis, Autoimmune, Experimental; Rats; Rats, Inbred Lew; Stilbenes; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
Role of cyclic nucleotides and calcium in the nutrient-induced release of cholecystokinin-like immunoreactivity in rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channels; Cholecystokinin; Colforsin; Dose-Response Relationship, Drug; Duodenum; Jejunum; Nucleotides, Cyclic; Radioimmunoassay; Rats; Receptors, Cholecystokinin; Tetradecanoylphorbol Acetate | 1992 |
Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells.
Topics: Alkaloids; Blotting, Northern; Cinnamates; Colforsin; Cycloheximide; Gene Expression; Genes, fos; Genistein; Humans; Isoflavones; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; RNA; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
IL-2 regulation of soluble IL-2 receptor levels following thermal injury.
Topics: Adult; Aged; Antigens, CD; Burns; Calcimycin; Calcium; CD5 Antigens; Colforsin; Humans; In Vitro Techniques; Indomethacin; Interleukin-1; Interleukin-2; Interleukin-3; Lymphocyte Activation; Middle Aged; Monocytes; Receptors, Interleukin-2; Solubility; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Astroglial membrane structure is affected by agents that raise cyclic AMP and by phosphatidylcholine phospholipase C.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Astrocytes; Cattle; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Freeze Fracturing; Glioma; Guinea Pigs; Immunohistochemistry; Isoproterenol; Lectins; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Protein Kinases; Rats; Retina; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1992 |
Effect of cAMP elevating compounds on inhibition of gap junctional communication and induction of morphological transformation in Syrian hamster embryo cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Communication; Cell Transformation, Neoplastic; Cells, Cultured; Cholera Toxin; Colforsin; Cricetinae; Cyclic AMP; Embryo, Mammalian; Intercellular Junctions; Mesocricetus; Tetradecanoylphorbol Acetate; Theophylline | 1992 |
Induction of ovulation and oocyte maturation of amphibian (Rana dybowskii) ovarian follicles by protein kinase C activation in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Colforsin; Cycloheximide; Enzyme Activation; Female; Isoquinolines; Oogenesis; Ovarian Follicle; Ovary; Ovulation Induction; Piperazines; Pituitary Gland; Progesterone; Protein Kinase C; Radioimmunoassay; Ranidae; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Modulation of interferon signaling in human fibroblasts by phorbol esters.
Topics: Base Sequence; Cell Line; Colforsin; DNA; DNA-Binding Proteins; Fibroblasts; Gene Expression Regulation; Humans; Interferon-alpha; Molecular Sequence Data; Promoter Regions, Genetic; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1992 |
Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Colforsin; Diterpenes; Enzyme Activation; Female; Genetic Variation; Kinetics; Ligands; Molecular Sequence Data; N-Methylaspartate; Oligodeoxyribonucleotides; Oocytes; Polyamines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, N-Methyl-D-Aspartate; RNA Splicing; Sphingosine; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Xenopus laevis | 1992 |
Regulation of apical Cl- conductance and basolateral K+ conductances by phorbol esters in HT-29cl.19A cells.
Topics: Calcium; Carcinoma; Cell Membrane; Chlorides; Colforsin; Colonic Neoplasms; Electric Conductivity; Humans; Phorbol 12,13-Dibutyrate; Potassium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Protein kinase C activators stimulate beta-endorphin secretion from hypothalamic cells.
Topics: Angiotensin II; Animals; Arginine Vasopressin; beta-Endorphin; Colforsin; Diglycerides; Enzyme Activation; Female; Hypothalamus; Neural Pathways; Pregnancy; Protein Kinase C; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1992 |
C-type natriuretic peptide in bovine chromaffin cells. The regulation of its biosynthesis and secretion.
Topics: Adrenal Medulla; Animals; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Colforsin; In Vitro Techniques; Natriuretic Peptide, C-Type; Nerve Tissue Proteins; Protein Kinase C; Protein Kinases; Protein Precursors; Tetradecanoylphorbol Acetate | 1992 |
PMA-sensitive protein kinase C is not necessary in TRH-stimulated prolactin release from female rat primary pituitary cells.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Diglycerides; Down-Regulation; Enzyme Activation; Female; Pituitary Gland, Anterior; Prolactin; Protein Kinase C; Radioimmunoassay; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1992 |
A selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-bromocinnamyl(amino)ethyl]-5-isoquinolinesulfonamide (H-89), inhibits phosphatidylcholine biosynthesis in HeLa cells.
Topics: Colforsin; HeLa Cells; Humans; Isoquinolines; Kinetics; Phosphatidylcholines; Protein Kinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate | 1992 |
Age- and strain-related differences in murine spleen cell responses to different activation signals.
Topics: Age Factors; Animals; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; CD3 Complex; Cell Division; Cells, Cultured; Colforsin; Interleukin-2; Interleukin-4; Lymphocyte Activation; Male; Mice; Mice, Inbred Strains; Receptors, Antigen, T-Cell; Recombinant Proteins; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
HLA-DR genes are silenced in human trophoblasts and stimulation of signal transduction pathways does not circumvent interferon-gamma unresponsiveness.
Topics: Calcimycin; Cholera Toxin; Colforsin; Female; Genes, MHC Class II; HLA-DR Antigens; Humans; Interferon-gamma; Ionomycin; Placenta; Platelet Activating Factor; Pregnancy; Receptors, Immunologic; Receptors, Interferon; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Trophoblasts; Virulence Factors, Bordetella | 1992 |
Multistep regulation of enhancer activity of the 21-base-pair element of human T-cell leukemia virus type I.
Topics: Base Sequence; Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; DNA, Viral; Enhancer Elements, Genetic; Gene Expression Regulation, Viral; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Molecular Sequence Data; Tetradecanoylphorbol Acetate; Transcription Factors | 1992 |
Participation of pertussis toxin-sensitive GTP-binding regulatory proteins in the suppression of baroreceptor reflex by neurotensin in the rat.
Topics: Animals; Cholera Toxin; Colforsin; Ethylmaleimide; GTP-Binding Proteins; Male; Neurotensin; Pertussis Toxin; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1992 |
TSH is able to induce cell cycle-related gene expression in rat thyroid cell.
Topics: Animals; Cell Cycle; Colforsin; Culture Media, Serum-Free; Gene Expression; Histones; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1992 |
Effects of glucocorticoid on corticotropin-releasing hormone gene regulation by second messenger pathways in NPLC and AtT-20 cells.
Topics: Animals; Colforsin; Corticotropin-Releasing Hormone; Cycloheximide; Dexamethasone; Gene Expression Regulation; Glucocorticoids; Humans; Liver Neoplasms; Mice; Protein Kinases; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Dexamethasone inhibits mitogen induction of the TIS10 prostaglandin synthase/cyclooxygenase gene.
Topics: 3T3 Cells; Animals; Blotting, Northern; Colforsin; Dexamethasone; Dinoprostone; Mice; Mitogens; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Modification of chromaffin cells with pertussis toxin or N-ethylmaleimide lowers cytoskeletal F-actin and enhances Ca(2+)-dependent secretion.
Topics: Actins; Adenosine Diphosphate Ribose; Adrenal Glands; Animals; Calcium; Cations, Divalent; Cattle; Chromaffin Granules; Colforsin; Cytoskeleton; Down-Regulation; Ethylmaleimide; Microscopy, Fluorescence; Norepinephrine; Pertussis Toxin; Protein Kinase C; Quinacrine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1992 |
Secretion of carboxypeptidase E from cultured astrocytes and from AtT-20 cells, a neuroendocrine cell line: implications for neuropeptide biosynthesis.
Topics: Animals; Astrocytes; Calcimycin; Carboxypeptidase H; Carboxypeptidases; Cells, Cultured; Colforsin; Isoproterenol; Methionine; Mice; Neuropeptides; Neurosecretory Systems; Pituitary Gland; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Time Factors; Vasoactive Intestinal Peptide | 1992 |
Fat-induced changes in mouse pancreatic islet insulin secretion, insulin biosynthesis and glucose metabolism.
Topics: Animals; Colforsin; Dietary Fats; Female; Glucose; Glutamine; Glycolysis; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred Strains; Plant Oils; Proinsulin; Reference Values; RNA, Messenger; Sunflower Oil; Tetradecanoylphorbol Acetate | 1992 |
The effects of a single intraoperative immersion in various chemical agents and electromagnetic field exposure on onlay bone grafts to the facial skeleton.
Topics: Animals; Bone and Bones; Bone Transplantation; Calcimycin; Colforsin; Electromagnetic Fields; Facial Bones; Glycerophosphates; Male; Rabbits; Tetradecanoylphorbol Acetate | 1992 |
Synergistic activation of the rat growth hormone promoter by Pit-1 and the thyroid hormone receptor.
Topics: Animals; Chloramphenicol O-Acetyltransferase; Colforsin; DNA; DNA-Binding Proteins; Gene Expression Regulation; Growth Hormone; Humans; Promoter Regions, Genetic; Rats; Receptors, Thyroid Hormone; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription Factor Pit-1; Transcription Factors; Transfection; Triiodothyronine | 1992 |
Cysteine proteinase inhibitor in cultured human medullary thyroid carcinoma cells.
Topics: Blotting, Northern; Butyrates; Butyric Acid; Carcinoma; Colforsin; Cystatin C; Cystatins; Gene Expression; Humans; Immunoenzyme Techniques; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Tumor Cells, Cultured | 1992 |
Proliferative response of smooth muscle cells in hypertension.
Topics: Adult; Aged; Animals; Autoradiography; Cell Count; Cell Division; Cells, Cultured; Colforsin; DNA; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Hypertension; Male; Mathematics; Middle Aged; Muscle, Smooth; Norepinephrine; Ploidies; Rats; Rats, Inbred WKY; Tetradecanoylphorbol Acetate; Thymidine; Tritium | 1992 |
Desensitization of the epidermal adenylate cyclase system: agonists and phorbol esters desensitize by independent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alkaloids; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Epidermis; Epinephrine; Histamine; Isoquinolines; Pertussis Toxin; Piperazines; Receptors, Adrenergic, beta; Receptors, Histamine; Skin; Staurosporine; Swine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Evidence for a defect in growth hormone-releasing factor signal transduction in the dwarf (dw/dw) rat pituitary.
Topics: Alprostadil; Animals; Body Weight; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dwarfism, Pituitary; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Immunohistochemistry; Kinetics; Male; Pituitary Gland, Anterior; Rats; Rats, Mutant Strains; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Effect of lithium on function and growth of thyroid cells in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Line; Colforsin; Cyclic AMP; Iodides; Isoquinolines; Lithium; Piperazines; Protein Kinase C; Rats; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Triiodothyronine | 1991 |
Different mechanisms of beta-adrenoceptor down-regulation by chronic imipramine and electroconvulsive treatment: possible role for protein kinase C.
Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Down-Regulation; Electroconvulsive Therapy; Imipramine; Isoproterenol; Male; Norepinephrine; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1991 |
Neutrophil beta-adrenergic receptor responses are potentiated by acute exposure to phorbol ester without changes in receptor distribution or coupling.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Humans; Isoproterenol; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase Inhibitors; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1991 |
NF-kappa B activation by tumor necrosis factor alpha in the Jurkat T cell line is independent of protein kinase A, protein kinase C, and Ca(2+)-regulated kinases.
Topics: Calcium; Cell Line; Cholera Toxin; Clone Cells; Colforsin; Cyclic AMP; Dinoprostone; Humans; Hydrogen-Ion Concentration; Kinetics; Lymphoma; NF-kappa B; Nigericin; Oligonucleotide Probes; Protein Kinase C; Protein Kinases; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Effect of different steroidogenic stimuli on protein phosphorylation and steroidogenesis in MA-10 mouse Leydig tumor cells.
Topics: Animals; Bucladesine; Chorionic Gonadotropin; Colforsin; Electrophoresis, Gel, Two-Dimensional; In Vitro Techniques; Leydig Cell Tumor; Leydig Cells; Male; Mice; Mitochondria; Phosphoproteins; Phosphorylation; Progesterone; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Differential regulation of protooncogenes c-jun and jun D expressions by protein tyrosine kinase, protein kinase C, and cyclic-AMP mitogenic pathways in dog primary thyrocytes: TSH and cyclic-AMP induce proliferation but downregulate C-jun expression.
Topics: Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dogs; Epidermal Growth Factor; Gene Expression Regulation; Kinetics; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Transcription Factors | 1991 |
Modulation of T-cell activation through protein kinase C- or A-dependent signalling pathways synergistically increases human immunodeficiency virus long terminal repeat induction by cytomegalovirus immediate-early proteins.
Topics: Antigens, CD; CD4 Antigens; Cell Line; Colforsin; Cyclic AMP; Cytomegalovirus; Dinoprostone; HIV Long Terminal Repeat; Humans; Kinetics; Lymphocyte Activation; Promoter Regions, Genetic; Protein Kinase C; Protein Kinases; Recombinant Proteins; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 1991 |
Protein kinase C, an endogenous regulator of hormone-induced cyclic AMP induction in porcine luteal cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Colforsin; Colistin; Corpus Luteum; Cyclic AMP; Female; Isoquinolines; Luteinizing Hormone; Phorbol Esters; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Sphingosine; Swine; Tetradecanoylphorbol Acetate | 1991 |
Multiple signalling pathways interact in the regulation of nerve growth factor production in L929 fibroblasts.
Topics: Animals; Bucladesine; Colforsin; Corticosterone; Culture Media; Cyclic AMP; Gene Expression; Genes, fos; Genes, jun; Kinetics; L Cells; Mice; Mifepristone; Nerve Growth Factors; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Striatal proenkephalin turnover and gene transcription are regulated by cyclic AMP and protein kinase C-related pathways.
Topics: Animals; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Enkephalin, Methionine; Enkephalins; Female; Immunohistochemistry; Neural Pathways; Neurons; Nucleic Acid Hybridization; Pregnancy; Protein Kinase C; Protein Precursors; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1991 |
Protein kinase C modulates cAMP content in proximal tubular cells: role of phosphodiesterase inhibition.
Topics: Angiotensin II; Animals; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; Kidney Tubules, Proximal; Norepinephrine; Parathyroid Hormone; Phosphodiesterase Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Activation of the CD3/T cell receptor (TcR) complex or of protein kinase C potentiate adenylyl cyclase stimulation in a tumoral T cell line: involvement of two distinct intracellular pathways.
Topics: Adenylyl Cyclases; Antigens, Differentiation, T-Lymphocyte; Arachidonic Acid; Calcium; CD3 Complex; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Humans; In Vitro Techniques; Inositol Phosphates; Leukemia, T-Cell; Muromonab-CD3; Protein Kinase C; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Human chorionic gonadotropin up-regulates insulin-like growth factor-I receptor gene expression of Leydig cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Gene Expression Regulation; Insulin-Like Growth Factor I; Kinetics; Leydig Cells; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Somatomedin; RNA, Messenger; Testosterone; Tetradecanoylphorbol Acetate; Up-Regulation | 1991 |
Evidence for a role of protein kinase-C in His-D-Trp-Ala-Trp-D-Phe-Lys-NH2-induced growth hormone release from rat primary pituitary cells.
Topics: Amino Acid Sequence; Animals; Calcimycin; Colforsin; Cyclic AMP; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Molecular Sequence Data; Oligopeptides; Phloretin; Pituitary Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1991 |
Impaired generation of cyclic adenosine 3',5'-monophosphate in a somatomammotroph cell line derived from dwarf (dw) rat anterior pituitaries.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Bucladesine; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dwarfism; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pituitary Gland, Anterior; Rats; Rats, Mutant Strains; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Modulation of muscarinic receptor-mediated adenylate cyclase and phospholipase C responses in rat retina.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bucladesine; Colforsin; Cyclic AMP; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Retina; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1991 |
cAMP stimulates protein kinase C activity in cultured renal LLC-PK1 cells.
Topics: Adenylyl Cyclases; Arginine Vasopressin; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Kidney; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Thionucleotides | 1991 |
Increased cyclic AMP levels enhance IL-1 alpha and IL-1 beta mRNA expression and protein production in human myelomonocytic cell lines and monocytes.
Topics: Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Hematopoietic Stem Cells; Humans; Interleukin-1; Lipopolysaccharides; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Roles of actin filaments and three second-messenger systems in short-term regulation of chick dorsal root ganglion neurite outgrowth.
Topics: Actins; Animals; Calcimycin; Calcium; Chick Embryo; Colforsin; Cryopreservation; Cyclic AMP; Cytochalasins; Cytoskeleton; Ganglia, Spinal; Microscopy, Electron; Neurons; Protein Kinase C; Pseudopodia; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C activating phorbolesters enhance the cyclic AMP response to parathyroid hormone, forskolin and choleratoxin in mouse calvarial bones and rat osteosarcoma cells.
Topics: Adenylyl Cyclases; Animals; Bone and Bones; Cattle; Cholera Toxin; Colforsin; Culture Techniques; Cyclic AMP; Enzyme Activation; Mice; Osteosarcoma; Parathyroid Hormone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Phorbol esters do not influence the maturation and the beta-adrenergic responsiveness of differentiated adipose precursor cells, cultured in a charcoal-treated serum medium.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Blood; Cell Differentiation; Cells, Cultured; Charcoal; Colforsin; Culture Media; Isoproterenol; Lipolysis; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Stem Cells; Tetradecanoylphorbol Acetate | 1991 |
Modulation of agonist-induced calcium mobilisation in bovine aortic endothelial cells by phorbol myristate acetate and cyclic AMP but not cyclic GMP.
Topics: Animals; Aorta; Arginine; Bradykinin; Calcium; Calcium Channel Agonists; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Isoproterenol; Nitroarginine; Nitroprusside; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Intracellular cAMP regulates the response to NMDA in hippocampal neurons.
Topics: Animals; Bucladesine; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Hippocampus; N-Methylaspartate; Neurons; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1991 |
Inhibition of protein kinase C activity in cultured pituitary cells attenuates both cyclic AMP-independent and -dependent secretion of ACTH.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Alkaloids; Animals; Arginine Vasopressin; Carcinogens; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Kinetics; Male; Phorbol Esters; Pituitary Gland, Anterior; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate; Veratridine | 1991 |
Stimulatory effects of brain natriuretic peptide on cyclic GMP accumulation and tyrosine hydroxylase activity in cultured bovine adrenal medullary cells.
Topics: Adrenal Medulla; Animals; Atrial Natriuretic Factor; Calcium; Cattle; Cell Membrane Permeability; Cells, Cultured; Colforsin; Cyclic GMP; Digitonin; Extracellular Space; Kinetics; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Phosphorylation; Sodium; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1991 |
Signal transduction systems in growth hormone-releasing hormone and somatostatin release from perifused rat hypothalamic fragments.
Topics: Animals; Calcimycin; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Growth Hormone-Releasing Hormone; Hypothalamus; In Vitro Techniques; Kinetics; Male; Perfusion; Protein Kinase C; Rats; Rats, Inbred Strains; Signal Transduction; Somatostatin; Tetradecanoylphorbol Acetate | 1991 |
Effects of second messenger system activation on functional expression of tyrosine hydroxylase fusion gene constructs in neuronal and nonneuronal cells.
Topics: Animals; Base Sequence; Blotting, Northern; Cells, Cultured; Chlorocebus aethiops; Colforsin; Cyclic AMP; Dexamethasone; Enzyme Induction; Fibroblasts; Glioma; HeLa Cells; Humans; Mice; Molecular Sequence Data; Neuroblastoma; Neurons; Organ Specificity; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1991 |
Protein kinase C activators sensitize cyclic AMP accumulation by intact 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Astrocytoma; Carbachol; Colforsin; Cyclic AMP; Down-Regulation; Enzyme Activation; Humans; Isoproterenol; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Forskolin-induced desensitization of pancreatic beta-cell insulin secretory responsiveness: possible involvement of impaired information flow in the inositol-lipid cycle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Diacylglycerol Kinase; Diglycerides; Glucose; Glycerides; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Male; Phosphatidylinositols; Phosphotransferases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenoma, Islet Cell; Animals; Carbachol; Colforsin; Cyclic AMP; Drug Synergism; Glipizide; Glucose; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Mice; Mice, Transgenic; Pancreatic Neoplasms; Potassium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
cAMP-mediated modulation of signal transduction of epidermal growth factor (EGF) receptor systems in human epidermoid carcinoma A431 cells. Depression of EGF-dependent diacylglycerol production and EGF receptor phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Epidermal Growth Factor; ErbB Receptors; Glycerides; Humans; Kinetics; Peptide Mapping; Phosphopeptides; Phosphorylation; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Synthesis and secretion of somatostatin-28 and -14 by fetal rat intestinal cells in culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Bucladesine; Butyrates; Butyric Acid; Cells, Cultured; Chromatography, Gel; Colforsin; Ethanol; Fetus; Fluorescent Antibody Technique; Intestinal Mucosa; Intestines; Protein Precursors; Rats; Rats, Inbred Strains; RNA; RNA, Messenger; Somatostatin; Somatostatin-28; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Phorbol esters enhance stretch-induced atrial natriuretic peptide secretion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Natriuretic Factor; Colforsin; Heart; Heart Atria; Male; Physical Stimulation; Radioimmunoassay; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
A growth factor-inducible nuclear protein with a novel cysteine/histidine repetitive sequence.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Southern; Cell Line; Cloning, Molecular; Colforsin; Escherichia coli; Fluorescent Antibody Technique; Liver; Liver Regeneration; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Nuclear Proteins; Repetitive Sequences, Nucleic Acid; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Zinc; Zinc Fingers | 1990 |
Modulation of the constitutive gene expression of the 55 kD tumor necrosis factor receptor in hematopoietic cells.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Carcinoma, Hepatocellular; Colforsin; Gene Expression Regulation; Humans; Leukemia, Promyelocytic, Acute; Leukocytes, Mononuclear; Liver Neoplasms; Molecular Weight; Neutrophils; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Reference Values; RNA; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1990 |
Expression of normal and cystic fibrosis phenotypes by continuous airway epithelial cell lines.
Topics: Antigens, Polyomavirus Transforming; Base Sequence; Biomarkers; Blood Proteins; Bradykinin; Calcimycin; Calgranulin A; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cystic Fibrosis; Epithelial Cells; Epithelium; Genotype; Humans; Ion Channels; Keratins; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Nasal Mucosa; Oligonucleotide Probes; Phenotype; Polymerase Chain Reaction; Reference Values; Retroviridae; Simian virus 40; Tetradecanoylphorbol Acetate; Theophylline | 1990 |
An alpha-subunit-secreting cell line derived from a mouse thyrotrope tumor.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dexamethasone; DNA-Binding Proteins; Gene Expression Regulation; Glycoprotein Hormones, alpha Subunit; Mice; Pituitary Gland, Anterior; Pituitary Neoplasms; Regulatory Sequences, Nucleic Acid; Second Messenger Systems; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Transcription Factors; Tumor Cells, Cultured | 1990 |
Stimulation of chicken growth hormone release by phorbol esters.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Growth Hormone; Growth Hormone-Releasing Hormone; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland, Anterior; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1990 |
Chloride channel blockers inhibit ACTH secretion from mouse pituitary tumor cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Adrenocorticotropic Hormone; Animals; Cell Line; Chloride Channels; Colforsin; Corticotropin-Releasing Hormone; Ion Channels; Kinetics; Membrane Proteins; Mice; ortho-Aminobenzoates; Osmolar Concentration; Pertussis Toxin; Pituitary Neoplasms; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Phorbol acetate enhances the phosphorylation of cytokeratins 8 and 18 in human colonic epithelial cells.
Topics: Blotting, Western; Colforsin; Colon; Cyclic AMP; Epithelium; Humans; Keratins; Peptide Mapping; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
The possibility of participation of different protein kinases in the regulation of degradation of Glp6[125I]Tyr8SP6-11 with different endopeptidases in subcellular fractions of rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Brain; Cell Nucleus; Cerebral Cortex; Colforsin; Cyclic AMP; Cyclic GMP; Endopeptidases; Hippocampus; Neurotransmitter Agents; Peptide Fragments; Protease Inhibitors; Protein Kinases; Pyrrolidonecarboxylic Acid; Rats; Second Messenger Systems; Subcellular Fractions; Substance P; Synaptosomes; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C and cyclic AMP modulate thrombin-induced platelet-activating factor synthesis in human endothelial cells.
Topics: Acetyltransferases; Arachidonic Acid; Arachidonic Acids; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Humans; Iloprost; Ionomycin; Kinetics; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Mammalian cell lines engineered to identify inhibitors of specific signal transduction pathways.
Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Animals; Base Sequence; Cell Line; Clone Cells; Colforsin; Female; Humans; Isoenzymes; Mice; Molecular Sequence Data; Placenta; Platelet-Derived Growth Factor; Pregnancy; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1991 |
TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Cell Line; Colforsin; DNA Probes; Enzyme Induction; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Mice; Molecular Sequence Data; Oligonucleotide Probes; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Conformation; RNA; RNA, Messenger; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate | 1991 |
Epidermal growth factor, a modulator of luteal adenylate cyclase. Characterization of epidermal growth factor receptors and its interaction with adenylate cyclase system in bovine luteal cell membrane.
Topics: Adenylyl Cyclases; Animals; Blotting, Western; Cattle; Cell Membrane; Colforsin; Corpus Luteum; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Female; In Vitro Techniques; Molecular Weight; Phosphorylation; Phosphotyrosine; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine | 1991 |
Expression of genes related to the extracellular matrix in human endothelial cells. Differential modulation by elevated glucose concentrations, phorbol esters, and cAMP.
Topics: 1-Methyl-3-isobutylxanthine; Basement Membrane; Blotting, Northern; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Endothelium, Vascular; Extracellular Matrix; Fibronectins; Gene Expression Regulation; Glucose; Humans; Microbial Collagenase; Protein Kinase C; Protein Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Transcription, Genetic | 1991 |
Activation of AP-1 by IL-1 and phorbol esters in T cells. Role of protein kinase A and protein phosphatases.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Synergism; Ethers, Cyclic; Gene Expression Regulation; Interleukin-1; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1991 |
Modification of biological responses to interleukin-1 by agents that perturb signal transduction pathways.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Flow Cytometry; Interleukin-1; Interleukin-2; Lymphocyte Activation; Mice; Pertussis Toxin; Protein Kinase C; Recombinant Proteins; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Regulation of Na-K-2Cl cotransport in osteoblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Cell Line; Chlorides; Colforsin; Cyclic AMP; Dinoprostone; Egtazic Acid; Kinetics; Osteoblasts; Osteosarcoma; Ouabain; Parathyroid Hormone; Potassium; Rubidium; Second Messenger Systems; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate | 1991 |
Hepatocanalicular organic-anion transport is regulated by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Anion Transport Proteins; Anions; Bile Canaliculi; Biological Transport; Bucladesine; Carrier Proteins; Colforsin; Cyclic AMP; Glucagon; Glutathione; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1991 |
Regulation by forskolin of cyclic AMP phosphodiesterase and protein kinase C activity in LLC-PK1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Cells, Cultured; Colforsin; Cyclic GMP; Galactose; Macaca mulatta; Pregnenolone; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C down-regulation enhances cAMP-mediated induction of urokinase-type plasminogen activator mRNA in LLC-PK1 cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Northern; Bucladesine; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Gene Expression; Protein Kinase C; Protein Kinases; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Urokinase-Type Plasminogen Activator | 1991 |
Regulation of peptide-YY synthesis and secretion in fetal rat intestinal cultures.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Colforsin; Drug Synergism; Gastric Inhibitory Polypeptide; Gastrin-Releasing Peptide; Immunoenzyme Techniques; Intestinal Mucosa; Intestines; Peptide Biosynthesis; Peptide YY; Peptides; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Effects of cyclic AMP and phorbol ester on transepithelial electrical resistance of Sertoli cell monolayers in two-compartment culture.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Electric Conductivity; Epithelium; Follicle Stimulating Hormone; Intercellular Junctions; Male; Rats; Rats, Inbred Strains; Second Messenger Systems; Sertoli Cells; Tetradecanoylphorbol Acetate | 1991 |
Triiodothyronine (T3) inhibition of growth hormone secretion by chicken pituitary cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Calcimycin; Cells, Cultured; Chickens; Colforsin; Diglycerides; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; In Vitro Techniques; Male; Pituitary Gland, Anterior; Radioimmunoassay; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triiodothyronine | 1991 |
Studies on the mechanism by which galanin inhibits insulin secretion in islets.
Topics: Animals; Bucladesine; Calcium Radioisotopes; Colforsin; Diazoxide; Galanin; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred Strains; Neuropeptides; Peptides; Permeability; Rats; Rats, Inbred Strains; Rubidium Radioisotopes; Tetradecanoylphorbol Acetate | 1991 |
Differential and coordinate regulation of TH and PNMT mRNAs in chromaffin cell cultures by second messenger system activation and steroid treatment.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Medulla; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Enzyme Induction; Phenylethanolamine N-Methyltransferase; RNA, Messenger; Second Messenger Systems; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1991 |
Release of corticotrophin-releasing factor-41, arginine vasopressin and oxytocin from rat fetal hypothalamic cells in culture: response to activation of intracellular second messengers and to corticosteroids.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Arginine Vasopressin; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Enzyme Activation; Female; Hypothalamus; Oxytocin; Protein Kinases; Rats; Rats, Inbred Strains; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1992 |
The bovine chromogranin A gene: structural basis for hormone regulation and generation of biologically active peptides.
Topics: Adrenal Medulla; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Blotting, Southern; Cattle; Cell Line; Cells, Cultured; Chromogranin A; Chromogranins; Cloning, Molecular; Colforsin; Dexamethasone; DNA; Gene Expression Regulation; Genomic Library; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Restriction Mapping; RNA, Messenger; Sequence Homology, Nucleic Acid; TATA Box; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Effects of 17 beta-estradiol on calcitonin secretion and content in a human medullary thyroid carcinoma cell line.
Topics: Calcitonin; Carcinoma; Colforsin; Dose-Response Relationship, Drug; Estradiol; Humans; Kinetics; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Tumor Cells, Cultured | 1991 |
Signal transduction pathway in gastric mucous cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Carbachol; Cell Membrane; Cholera Toxin; Colforsin; Cytosol; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Gastric Mucosa; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Phosphatidylserines; Protein Kinase C; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
PLC gamma 1, a possible mediator of T cell receptor function.
Topics: Antigens, Differentiation, T-Lymphocyte; Blotting, Western; CD3 Complex; Colforsin; Enzyme Activation; Humans; Leukemia; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinases; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1991 |
Possible involvement of protein phosphorylation in the regulation of the sulphonylurea receptor of a pancreatic beta-cell line, HIT T15.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cell Line; Cell Membrane; Colforsin; Diazoxide; Glyburide; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Phosphorylation; Piperazines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Kinase Inhibitors; Proteins; Receptors, Drug; Rubidium; Sulfonylurea Receptors; Tetradecanoylphorbol Acetate | 1991 |
The expression of IL-2R alpha-chain is enhanced by activation of adenylate cyclase in large granular lymphocytes and natural killer cells.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Cell Division; Cell Line; Colforsin; Cyclic AMP; Gene Expression; Humans; In Vitro Techniques; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Macromolecular Substances; Mice; Mice, Inbred C57BL; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and cAMP in reactivation of viral latency.
Topics: Animals; Base Sequence; Bucladesine; Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Enhancer Elements, Genetic; Genes, Viral; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Growth Factors; Promoter Regions, Genetic; Restriction Mapping; Simplexvirus; TATA Box; Tetradecanoylphorbol Acetate; Transcription, Genetic; Vero Cells | 1991 |
Up-regulation of fibroblast growth factor (FGF) receptor mRNA levels by basic FGF or testosterone in androgen-sensitive mouse mammary tumor cells.
Topics: Animals; Colforsin; Cycloheximide; Dose-Response Relationship, Drug; Fibroblast Growth Factors; Mammary Neoplasms, Experimental; Mice; Receptors, Cell Surface; Receptors, Fibroblast Growth Factor; RNA, Messenger; Testosterone; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1991 |
Inhibition by phorbol ester of cellular adenosine 3',5'-monophosphate production and cellular free calcium mobilization in response to arginine vasopressin in rat renal papillary collecting tubule cells in culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Isoquinolines; Kidney Medulla; Kidney Tubules, Collecting; Male; Osmolar Concentration; Piperazines; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
See-saw signal processing: reciprocal effects of stimulus deprivation on vasoactive intestinal peptide-stimulated adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate accumulation in rat pinealocytes.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Light; Male; Phenylephrine; Pineal Gland; Potassium; Rats; Rats, Inbred Strains; Sensory Deprivation; Signal Transduction; Sympathomimetics; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1991 |
Stimulation by Bt2cAMP of epidermal mucous metaplasia in retinol-pretreated chick embryonic cultured skin, and its inhibition by herbimycin A, an inhibitor for protein-tyrosine kinase.
Topics: Adenylyl Cyclases; Animals; Benzoquinones; Bucladesine; Chick Embryo; Clusterin; Colforsin; Cytoplasmic Granules; Epidermis; Glycoproteins; Lactams, Macrocyclic; Metaplasia; Molecular Chaperones; Mucous Membrane; Organ Culture Techniques; Protein Kinase C; Protein-Tyrosine Kinases; Quinones; Rifabutin; Skin; Tetradecanoylphorbol Acetate; Vitamin A | 1991 |
Cyclic AMP- and phorbol ester-induced transcriptional activation are mediated by the same enhancer element in the human vasoactive intestinal peptide gene.
Topics: Base Sequence; Blotting, Northern; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Enhancer Elements, Genetic; Gene Expression Regulation; Metallothionein; Molecular Sequence Data; Mutation; Plasmids; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Vasoactive Intestinal Peptide | 1991 |
Phorbol-ester-induced phosphorylation of the beta 2-adrenergic receptor decreases its coupling to Gs.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cloning, Molecular; Colforsin; Cricetinae; DNA Mutational Analysis; GTP-Binding Proteins; Isoproterenol; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Receptors, Adrenergic, beta; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Effect of dexamethasone on parathyroid hormone (PTH) and PTH-related protein regulated phosphate uptake in opossum kidney cells.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Kidney; Opossums; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Phorbol Esters; Phosphates; Proteins; Receptors, Cell Surface; Receptors, Parathyroid Hormone; Sodium; Teriparatide; Tetradecanoylphorbol Acetate | 1991 |
Hormonal regulation of matrix metalloproteinase inhibitors in rat granulosa cells and ovaries.
Topics: Animals; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Extracellular Matrix; Female; Glycoproteins; Gonadotropins, Equine; Granulosa Cells; Luteinizing Hormone; Metalloendopeptidases; Ovary; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinases | 1991 |
Thapsigargin potentiates histamine-stimulated HCl secretion in gastric parietal cells but does not mimic cholinergic responses.
Topics: Aminopyrine; Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Drug Synergism; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Rabbits; Receptors, Cholinergic; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1991 |
Time-dependent biphasic regulation of Na+/K+/Cl- cotransport in rat glomerular mesangial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Biological Transport; Bumetanide; Calcimycin; Chlorides; Colforsin; Glomerular Mesangium; In Vitro Techniques; Potassium; Rats; Sodium; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1991 |
Sensitization of adenylyl cyclase by P2 purinergic and M5 muscarinic receptor agonists in L cells.
Topics: Adenosine Triphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; Carbachol; Colforsin; Cricetinae; Down-Regulation; Drug Synergism; Kinetics; L Cells; Magnesium; Mice; Phosphatidylinositols; Protein Kinase C; Receptors, Muscarinic; Receptors, Purinergic; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1991 |
Covalent linkage between nucleotides and platelet-derived endothelial cell growth factor.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Colforsin; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Humans; Molecular Sequence Data; Nucleotides; Phosphorylation; Precipitin Tests; Tetradecanoylphorbol Acetate; Thymidine Phosphorylase; Tumor Cells, Cultured | 1991 |
Elevation of AP1 activity during F9 cell differentiation is due to increased c-jun transcription.
Topics: Base Sequence; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genetic Markers; Humans; Molecular Sequence Data; Multigene Family; Proto-Oncogene Proteins c-jun; RNA, Messenger; Stem Cells; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1990 |
Inhibitory guanine nucleotide binding protein in pig epidermis: regulation of epidermal adenylate cyclase.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Epidermis; GTP-Binding Proteins; Pertussis Toxin; Swine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Parathyroid hormone blocks the stimulatory effect of insulin-like growth factor-I on collagen synthesis in cultured 21-day fetal rat calvariae.
Topics: Animals; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Female; Insulin-Like Growth Factor I; Male; Parathyroid Hormone; Proline; Protein Kinase C; Rats; Rats, Inbred Strains; Skull; Tetradecanoylphorbol Acetate; Tritium | 1990 |
[Effect of a phorbol ester (PMA) and forskolin of the G-/F-actin equilibrium in human platelets].
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Actins; Cells, Cultured; Colforsin; Cyclic AMP; Deoxyribonuclease I; Humans; Kinetics; Tetradecanoylphorbol Acetate | 1990 |
Tissue-specific, cyclic adenosine 3',5'-monophosphate-induced, and phorbol ester-repressed transcription from the human P450c17 promoter in mouse cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Glands; Aldehyde-Lyases; Animals; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; Chromosome Deletion; Colforsin; Cyclic AMP; Cytochrome P-450 Enzyme System; Dexamethasone; Gene Expression; Humans; Male; Mice; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; Steroid 17-alpha-Hydroxylase; Testis; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1990 |
Further evidence for abnormal protein kinase C regulation of macromolecule secretion in fibroblasts from cystic fibrosis patients.
Topics: Binding Sites; Bucladesine; Calcimycin; Cells, Cultured; Colforsin; Cystic Fibrosis; Dose-Response Relationship, Drug; Fibroblasts; Glycoconjugates; Humans; Isoproterenol; Phorbol 12,13-Dibutyrate; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate | 1990 |
Alterations in beta-adrenoceptor density on T-lymphocytes upon activation with interleukin-2 and phytohaemagglutinin.
Topics: Adenylyl Cyclases; Colforsin; Cyclic AMP; Down-Regulation; Drug Interactions; Enzyme Activation; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Interleukin-2; Isoproterenol; Kinetics; Lymphocyte Activation; Phytohemagglutinins; Protein Kinase C; Receptors, Adrenergic, beta; Second Messenger Systems; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Regulation of tyrosine hydroxylase activity in pheochromocytoma PC-12 cells by bradykinin.
Topics: Animals; Bradykinin; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Lanthanum; Nifedipine; Pheochromocytoma; Phosphorylation; Potassium; Rats; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1990 |
Modulation of growth hormone (GH) secretion and GH mRNA levels by GH-releasing factor, somatostatin and secretagogues in cultured bovine adenohypophysial cells.
Topics: Animals; Bucladesine; Cattle; Cells, Cultured; Colforsin; Growth Hormone; Growth Hormone-Releasing Hormone; Pituitary Gland, Anterior; RNA, Messenger; Somatostatin; Tetradecanoylphorbol Acetate | 1990 |
Gastrin secretion from human antral G cells in culture.
Topics: Bombesin; Calcimycin; Cells, Cultured; Chromaffin System; Colforsin; Enterochromaffin Cells; Gastrins; Humans; Pyloric Antrum; Receptors, Gastrointestinal Hormone; Somatostatin; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1990 |
Release of somatostatin immunoreactivity from human antral D cells in culture.
Topics: Adult; Bombesin; Calcimycin; Cells, Cultured; Colforsin; Female; Gastric Mucosa; Gastrins; Humans; Male; Pyloric Antrum; Radioimmunoassay; Reference Values; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate | 1990 |
Growth hormone and prolactin secretion in cultured somatomammotroph cells.
Topics: Animals; Bucladesine; Cell Line; Colforsin; Diglycerides; Growth Hormone; Growth Hormone-Releasing Hormone; Pituitary Gland; Prolactin; Rats; Somatostatin; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1990 |
Delineation of the mechanism of inhibition of human T cell activation by PGE2.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Blotting, Northern; CD28 Antigens; CD3 Complex; CD4-Positive T-Lymphocytes; Cholera Toxin; Colforsin; Cyclic AMP; Dideoxyadenosine; Dinoprostone; Gene Expression; Humans; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Phytohemagglutinins; Receptors, Antigen, T-Cell; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Insulin secretory response to secretagogues by perifused islets from chronically glucose-infused rats.
Topics: Animals; Colforsin; Glucose; In Vitro Techniques; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Leucine; Male; Perfusion; Rats; Rats, Mutant Strains; Tetradecanoylphorbol Acetate; Thinness; Tolbutamide | 1991 |
Down-regulation of cystic fibrosis gene mRNA transcript levels and induction of the cystic fibrosis chloride secretory phenotype in epithelial cells by phorbol ester.
Topics: Blotting, Northern; Chlorides; Colforsin; Cystic Fibrosis; Down-Regulation; Epithelial Cells; Epithelium; Humans; Phenotype; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1991 |
Expression of a chimeric VIP gene is targeted to the intestine in transgenic mice.
Topics: Animals; Base Sequence; Chimera; Chloramphenicol O-Acetyltransferase; Colforsin; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Luciferases; Mice; Mice, Transgenic; Molecular Sequence Data; Neuroblastoma; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1990 |
Calcitonin inhibits basal and thyrotropin-releasing hormone-induced release of prolactin from anterior pituitary cells: evidence for a selective action exerted proximal to secretagogue-induced increases in cytosolic Ca2+.
Topics: Animals; Calcimycin; Calcitonin; Calcium; Colforsin; Cytosol; Female; In Vitro Techniques; Kinetics; Pituitary Gland, Anterior; Prolactin; Rats; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Time Factors; Vasoactive Intestinal Peptide | 1990 |
Response to IL-6 stimulation of human hepatoblastoma cells: production of pancreatic secretory trypsin inhibitor.
Topics: Animals; Biological Factors; Calcimycin; Colforsin; Cycloheximide; Cytokines; Humans; Interleukin-6; Lipopolysaccharides; Liver Neoplasms, Experimental; Lymphocyte Activation; Tetradecanoylphorbol Acetate; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tumor Cells, Cultured | 1990 |
Influx of extracellular calcium mediates 1,25-dihydroxyvitamin D3-dependent transcaltachia (the rapid stimulation of duodenal Ca2+ transport).
Topics: Animals; Biological Transport; Calcitriol; Calcium; Chickens; Colforsin; Duodenum; Egtazic Acid; Extracellular Space; Fluorescent Dyes; Fura-2; Ionomycin; Male; Osmolar Concentration; Potassium Chloride; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex.
Topics: Animals; Base Sequence; Cells, Cultured; Chick Embryo; Colforsin; DNA-Binding Proteins; Fibroblasts; Gene Expression Regulation; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Oligonucleotide Probes; Ovalbumin; Promoter Regions, Genetic; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Receptors, Estrogen; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 1990 |
Channel-mediated and carrier-mediated uptake of K+ into cultured ovine oligodendrocytes.
Topics: Animals; Biological Transport, Active; Cells, Cultured; Colforsin; Membrane Potentials; Oligodendroglia; Potassium; Potassium Channels; Potassium Radioisotopes; Protein Kinase C; Sheep; Tetradecanoylphorbol Acetate | 1990 |
Modes of inhibitory action of 4 beta-phorbol 12-myristate 13-acetate in thrombin-stimulated arachidonic acid release in intact and permeabilized platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cell Membrane Permeability; Chlorides; Colforsin; Cyclic AMP; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Piperazines; Protein Kinase Inhibitors; Rabbits; Serotonin; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Regulation of Na+/H+ and Cl-/HCO3- antiports in Vero cells.
Topics: Animals; Bicarbonates; Carrier Proteins; Chlorides; Colforsin; Culture Media; Cytosol; Growth Substances; Hydrogen-Ion Concentration; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Vero Cells | 1990 |
Activin-A modulates growth hormone secretion from cultures of rat anterior pituitary cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Activins; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dactinomycin; Dexamethasone; Growth Hormone; Growth Hormone-Releasing Hormone; Inhibins; Kinetics; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Stimulation of progesterone receptors by phorbol ester and cyclic AMP in fetal uterine cells in culture.
Topics: Animals; Bucladesine; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Estradiol; Female; Guinea Pigs; Kinetics; Protein Kinase C; Receptors, Progesterone; Tamoxifen; Tetradecanoylphorbol Acetate; Uterus | 1990 |
Modulation of interleukin-1 beta production by cyclic AMP in human monocytes.
Topics: Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; Monocytes; Tetradecanoylphorbol Acetate | 1990 |
Decreased secretion due to a Ca2+ influx defect in frog peptic cells isolated with EGTA.
Topics: Acetylcholine; Animals; Bombesin; Calcium; Cell Membrane; Cell Separation; Colforsin; Cytochalasin B; Egtazic Acid; Esophagus; In Vitro Techniques; Isoproterenol; Kinetics; Microscopy, Electron; Pepsinogens; Rana catesbeiana; Receptors, Bombesin; Receptors, Muscarinic; Receptors, Neurotransmitter; Tetradecanoylphorbol Acetate | 1990 |
Transcriptional regulation of the neuropeptide Y gene by nerve growth factor: antagonism by glucocorticoids and potentiation by adenosine 3',5'-monophosphate and phorbol ester.
Topics: Adenosine Monophosphate; Adenylyl Cyclases; Adrenal Gland Neoplasms; Animals; Colforsin; Cyclic AMP; Glucocorticoids; Nerve Growth Factors; Neuropeptide Y; Pheochromocytoma; Phorbol Esters; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Regulation of protooncogenes c-fos and c-myc expressions by protein tyrosine kinase, protein kinase C, and cyclic AMP mitogenic pathways in dog primary thyrocytes: a positive and negative control by cyclic AMP on c-myc expression.
Topics: Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dogs; Down-Regulation; Epidermal Growth Factor; Gene Expression Regulation; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1990 |
Calcitonin decreases thyrotropin-releasing hormone-stimulated prolactin release through a mechanism that involves inhibition of inositol phosphate production.
Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Calcitonin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Female; Inositol Phosphates; Marine Toxins; Neurotensin; Oxocins; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1990 |
Role of protein kinase-C in the adrenocorticotropin secretory response to arginine vasopressin (AVP) and the synergistic response to AVP and corticotropin-releasing factor by perifused rat anterior pituitary cells.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Diglycerides; Dimethyl Sulfoxide; Drug Synergism; Kinetics; Male; Pituitary Gland, Anterior; Potassium Chloride; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Evidence for involvement of protein kinase C and cyclic adenosine 3',5' monophosphate-dependent protein kinase in the 1,25-dihydroxy-vitamin D3-mediated rapid stimulation of intestinal calcium transport, (transcaltachia).
Topics: Alkaloids; Animals; Biological Transport; Calcitriol; Calcium; Chickens; Colforsin; Cyclic AMP; Duodenum; Intestinal Mucosa; Intestines; Kinetics; Male; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil; Vitamin D Deficiency | 1990 |
Protein kinase C and Gi-protein mediated modulation of cAMP production in different stages of the rat seminiferous epithelium.
Topics: Adenylate Cyclase Toxin; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Follicle Stimulating Hormone; GTP-Binding Proteins; Male; Pertussis Toxin; Protein Kinase C; Rats; Rats, Inbred Strains; Seminiferous Epithelium; Signal Transduction; Testis; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
BK virus early RNA transcripts in stably transformed cells: enhanced levels induced by dibutyryl cyclic AMP, forskolin and 12-O-tetradecanoylphorbol-13-acetate treatment.
Topics: Animals; Base Sequence; BK Virus; Blotting, Southern; Bucladesine; Cell Line; Cell Transformation, Neoplastic; Colforsin; Cricetinae; DNA, Single-Stranded; DNA, Viral; Genes, Viral; Molecular Sequence Data; Nucleic Acid Hybridization; Oligonucleotide Probes; Polymerase Chain Reaction; Polyomavirus; RNA, Viral; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Granulosa cells from pig follicles of different sizes demonstrate maturational differences in their steroidogenic responses to FSH, calcium ionophore A23187, and phorbol diester.
Topics: Animals; Bucladesine; Calcimycin; Cells, Cultured; Colforsin; Estradiol; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Granulosa Cells; Progesterone; Stimulation, Chemical; Swine; Tetradecanoylphorbol Acetate | 1990 |
Orthovanadate and fluoroaluminate stimulate inositol phosphate production and in vitro ovulation in goldfish (Carassius auratus) follicles.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Calcimycin; Chlorides; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Cyprinidae; Dinoprost; Female; Goldfish; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Ovarian Follicle; Ovulation; Sodium Fluoride; Tetradecanoylphorbol Acetate; Vanadates | 1990 |
2',3'cyclic nucleotide-3'-phosphodiesterase in peripheral nerve myelin is phosphorylated by a phorbol ester-sensitive protein kinase.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Cell-Free System; Colforsin; Female; Myelin Proteins; Phosphoric Diester Hydrolases; Phosphorylation; Protein Kinases; Rats; Rats, Inbred Strains; Sciatic Nerve; Second Messenger Systems; Substrate Specificity; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Inhibitory effect of phorbol ester on sodium transport in frog urinary bladder.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine Vasopressin; Biological Transport; Colforsin; Cyclic AMP; Diglycerides; Rana catesbeiana; Sodium; Sphingosine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1990 |
Enhancement of cyclic AMP metabolism in a B cell line by protein kinase C.
Topics: Alkaloids; Alprostadil; B-Lymphocytes; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Down-Regulation; Drug Synergism; Humans; Immunoglobulin M; In Vitro Techniques; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Regulation of 11 beta- and 17 alpha-hydroxylases in cultured bovine adrenocortical cells: 3', 5'-cyclic adenosine monophosphate, insulin-like growth factor-I, and activators of protein kinase C.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Alprostadil; Animals; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Induction; Insulin; Insulin-Like Growth Factor I; Male; Protein Kinase C; RNA, Messenger; Somatomedins; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Tetradecanoylphorbol Acetate | 1990 |
Identification of a specific domain in the beta-adrenergic receptor required for phorbol ester-induced inhibition of catecholamine-stimulated adenylyl cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Colforsin; Epinephrine; GTP-Binding Proteins; Guanosine Triphosphate; L Cells; Magnesium; Mice; Pertussis Toxin; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
12-O-tetradecanoylphorbol 13-acetate potentiates the action of cAMP in inducing DNA cleavage in thymocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Kinetics; Male; Mice; Mice, Inbred BALB C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Two signal transduction pathways mediate interleukin-1 receptor expression in Balb/c3T3 fibroblasts.
Topics: Alkaloids; Animals; Cell Line; Colforsin; Cyclic AMP; Drug Synergism; Fibroblasts; Gene Expression; Interleukin-1; Mice; Mice, Inbred BALB C; Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinases; Receptors, Immunologic; Receptors, Interleukin-1; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Activation of intracellular pathways with forskolin and phorbol ester increases LHRH mRNA level in the rat hypothalamus superfused in vitro.
Topics: Animals; Base Sequence; Colforsin; Cyclic AMP; Female; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Kinetics; Molecular Sequence Data; Oligonucleotide Probes; Rats; Rats, Inbred Strains; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
Parathyroid hormone regulation of Na+/H+ exchange in opossum kidney cells: polarity and mechanisms.
Topics: Amiloride; Animals; Anti-Arrhythmia Agents; Carrier Proteins; Cell Line; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Fluorometry; Hydrogen-Ion Concentration; Kidney; Opossums; Parathyroid Hormone; Protein Kinases; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1990 |
cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Humans; Interleukin-1; Interleukin-2; Interleukin-4; Plasmids; Promoter Regions, Genetic; Recombinant Proteins; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1990 |
Control of interleukin-1 beta expression by protein kinase C and cyclic adenosine monophosphate in myeloid leukemia cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Gene Expression; Humans; Interleukin-1; Isoquinolines; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Effects of beta-adrenergic receptor activation, cholera toxin and forskolin on human natural killer cell function.
Topics: Adenosine Diphosphate Ribose; Calcimycin; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Cytotoxicity, Immunologic; Epinephrine; Humans; In Vitro Techniques; Isoproterenol; Killer Cells, Natural; Kinetics; Lymphocyte Activation; Membrane Proteins; NAD; Phosphorus Radioisotopes; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1990 |
Regulation of mRNA expression of 3 beta-hydroxy-5-ene steroid dehydrogenase in porcine granulosa cells in culture: a role for the protein kinase-C pathway.
Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; Female; Granulosa Cells; Kinetics; Luteinizing Hormone; Protein Kinase C; RNA, Messenger; Swine; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Potentiation of oncogenic N-ras-induced neurite outgrowth and ornithine decarboxylase activity by phorbol dibutyrate and protein kinase inhibitor H-8.
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Dexamethasone; Epidermal Growth Factor; Isoquinolines; Nerve Growth Factors; Neurons; Oncogene Protein p21(ras); Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
Modulation of vincristine sensitivity of human kidney tumor cells by pharmacological agents interfering with intracellular signals. No apparent relationship to changes in cytoplasmic Ca2+ or pH.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenocarcinoma; Calcium; Colforsin; Cytoplasm; Humans; Hydrogen-Ion Concentration; Isoquinolines; Kidney Neoplasms; Piperazines; Protein Kinase C; Sensitivity and Specificity; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vincristine | 1990 |
Involvement of cyclic AMP-dependent protein kinases in the signal transduction pathway for interleukin-1.
Topics: Carrier Proteins; Cell Line; Colforsin; DNA-Binding Proteins; Enhancer Elements, Genetic; Enzyme Inhibitors; Gene Expression Regulation; Humans; Interleukin-1; Intracellular Signaling Peptides and Proteins; Killer Cells, Natural; NF-kappa B; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 1990 |
Cell type-specific mechanisms of regulating expression of the ornithine decarboxylase gene after growth stimulation.
Topics: Animals; Cattle; Cell Division; Cell Nucleus; Colforsin; Fibroblasts; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Mice; Ornithine Decarboxylase; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cells.
Topics: Acetamides; Antigens, Neoplasm; Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Colforsin; Dimethylformamide; Fluorescent Antibody Technique; Humans; Membrane Glycoproteins; Mucin-1; Receptors, Estrogen; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1990 |
Analysis of the primary signals required for activation of the mitogenic pathway in murine thymocytes from protein phosphorylation patterns.
Topics: Animals; Calcimycin; Colforsin; Concanavalin A; Diglycerides; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Isoelectric Point; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Molecular Weight; Phosphoproteins; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Regulation of human renin expression in chorion cell primary cultures.
Topics: Calcimycin; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Chorion; Colforsin; Enzyme Precursors; Female; Gene Expression Regulation, Enzymologic; Humans; Kinetics; Plasmids; Renin; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection | 1990 |
Inhibitory effects of a tumor-promoting phorbol ester on luteinizing hormone-stimulated renin and prorenin production by cultured bovine theca cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carcinogens; Cattle; Cells, Cultured; Colforsin; Enzyme Precursors; Female; Luteinizing Hormone; Osmolar Concentration; Renin; Tetradecanoylphorbol Acetate; Theca Cells; Time Factors | 1990 |
On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: enhancer, TATA box, and RNA start site (Inr motif) occlusion.
Topics: Base Sequence; Colforsin; Dexamethasone; Enhancer Elements, Genetic; Feedback; Gene Expression; Genes, Suppressor; HeLa Cells; Humans; Interleukin-1; Interleukin-6; Molecular Sequence Data; Oligonucleotide Probes; Promoter Regions, Genetic; Receptors, Glucocorticoid; Restriction Mapping; RNA, Neoplasm; Second Messenger Systems; TATA Box; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 1990 |
Estradiol increases phosphorylation of the 90 kDa heat shock protein not associated with estradiol receptor in MCF-7 cells in culture.
Topics: Blotting, Western; Breast Neoplasms; Calcimycin; Colforsin; Estradiol; Heat-Shock Proteins; Humans; Phosphorylation; Receptors, Estrogen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Synergistic induction of interleukin 2 receptor (TAC) expression on YT cells by simultaneous activation of distinct signal transduction pathways.
Topics: Adenylyl Cyclases; Alkaloids; Colforsin; Humans; Interleukin-1; Killer Cells, Natural; Leukemia; Protein Kinase C; Receptors, Interleukin-2; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
12-O-tetradecanoylphorbol 13-acetate and forskolin modify muscarinic receptor-linked Ca2+ mobilization in SH-SY5Y neuroblastoma cells through different mechanisms.
Topics: Benzofurans; Binding, Competitive; Biomechanical Phenomena; Calcium; Carbachol; Colforsin; Cytosol; Fluorescent Dyes; Fura-2; Ionomycin; Membrane Potentials; N-Methylscopolamine; Neuroblastoma; Osmolar Concentration; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Adenosine A1 receptor-mediated inhibition of surfactant secretion in rat type II pneumocytes.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Choline; Colforsin; Diglycerides; Ionomycin; Kinetics; Lung; Male; Phosphatidylcholines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Terbutaline; Tetradecanoylphorbol Acetate | 1990 |
Cathepsin G binding to human platelets. Evidence for a specific receptor.
Topics: Blood Platelets; Calcium; Cathepsin G; Cathepsins; Cold Temperature; Colforsin; Cytosol; Humans; Kinetics; Neutrophils; Phenylmethylsulfonyl Fluoride; Platelet Activation; Protein Conformation; Serine Endopeptidases; Temperature; Tetradecanoylphorbol Acetate | 1990 |
Transfection of calcitonin gene regulatory elements into a cell culture model of the C cell.
Topics: Animals; Base Sequence; Calcitonin; Cloning, Molecular; Colforsin; DNA; Growth Hormone; Humans; Models, Biological; Molecular Sequence Data; Plasmids; Regulatory Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Thyroid Gland; Transfection; Tumor Cells, Cultured | 1990 |
Intracellular mechanisms governing the acute phase of beta-endorphin secretion from the corticotrope in vitro.
Topics: Animals; Colforsin; Endorphins; In Vitro Techniques; Pituitary Gland, Anterior; Protein Kinases; Second Messenger Systems; Sheep; Tetradecanoylphorbol Acetate | 1990 |
Second messengers involved in the regulation of corticotropin-releasing hormone mRNA and peptide in cultured rat fetal hypothalamic primary cultures.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Enzyme Activation; Gene Expression Regulation; Hypothalamus; Kinetics; Neurons; Potassium; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1990 |
Phosphorylation of stathmin and other proteins related to nerve growth factor-induced regulation of PC12 cells.
Topics: Adenosine; Adrenal Gland Neoplasms; Animals; Cell Line; Colforsin; Electrophoresis, Gel, Two-Dimensional; Microtubule Proteins; Neoplasm Proteins; Nerve Growth Factors; Pheochromocytoma; Phosphoproteins; Phosphorylation; Rats; Stathmin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Bombesin-like peptides stimulate gastrin release from isolated rat G-cells.
Topics: Amino Acid Sequence; Animals; Bombesin; Centrifugation; Colforsin; Female; Gastric Mucosa; Gastrins; In Vitro Techniques; Molecular Sequence Data; Neurokinin B; Peptide Fragments; Rats; Rats, Inbred Strains; Sulfonamides; Tetradecanoylphorbol Acetate | 1990 |
Effects of isoproterenol on histamine release induced from monodispersed guinea-pig lung cells by different secretagogues.
Topics: Animals; Antigens; Bucladesine; Calcimycin; Calcium; Colforsin; Diterpenes; Female; Guinea Pigs; Histamine Release; In Vitro Techniques; Isoproterenol; Lung; Ovalbumin; Tetradecanoylphorbol Acetate | 1985 |
Plasma membrane calcium flux, protein kinase C activation and smooth muscle contraction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cell Membrane; Colforsin; Drug Synergism; Enzyme Activation; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Ouabain; Perfusion; Phospholipids; Potassium; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Vasoconstriction | 1985 |
Hormone secretagogues increase cytosolic calcium by increasing cAMP in corticotropin-secreting cells.
Topics: Adrenocorticotropic Hormone; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cytosol; Dose-Response Relationship, Drug; Electric Conductivity; Ion Channels; Isoproterenol; Mice; Pituitary Gland; Secretory Rate; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1985 |
Activation of tracheal smooth muscle contraction: synergism between Ca2+ and activators of protein kinase C.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Cattle; Colforsin; Diterpenes; Drug Synergism; Enzyme Activation; Ethers; In Vitro Techniques; Ionomycin; Muscle Contraction; Muscle, Smooth; Nifedipine; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Trachea | 1985 |
Atrial natriuretic factor does not affect basal, forskolin- and CRF-stimulated adenylate cyclase activity, cAMP formation or ACTH secretion, but does stimulate cGMP synthesis in anterior pituitary.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Atrial Natriuretic Factor; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic GMP; Growth Hormone; Kinetics; Mice; Nifedipine; Pituitary Gland, Anterior; Potassium Chloride; Tetradecanoylphorbol Acetate | 1986 |
Ca2+-, phorbol ester-, and cAMP-stimulated enzyme secretion from permeabilized rat pancreatic acini.
Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amylases; Animals; Calcium; Carbachol; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cytoplasmic Granules; Digitonin; Egtazic Acid; Pancreas; Phorbols; Rats; Rats, Inbred Strains; Saponins; Spermine; Tetradecanoylphorbol Acetate; Trifluoperazine | 1986 |
P19, a hormonally regulated phosphoprotein of peptide hormone-producing cells: secretagogue-induced phosphorylation in AtT-20 mouse pituitary tumor cells and in rat and hamster insulinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenoma, Islet Cell; Adrenocorticotropic Hormone; Animals; Colforsin; Corticotropin-Releasing Hormone; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Glucagon; Insulinoma; Isoproterenol; Pancreatic Neoplasms; Phosphoproteins; Phosphorylation; Pituitary Neoplasms; Potassium; Rats; Tetradecanoylphorbol Acetate | 1986 |
Studies on the hepatic calcium-mobilizing activity of aluminum fluoride and glucagon. Modulation by cAMP and phorbol myristate acetate.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adrenergic alpha-Agonists; Aluminum; Aluminum Compounds; Angiotensin II; Calcium; Colforsin; Cyclic AMP; Drug Synergism; Fluorides; Glucagon; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Pertussis Toxin; Phorbols; Protein Kinase C; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thionucleotides; Vasopressins; Virulence Factors, Bordetella | 1986 |
The phorbol ester induced atrial natriuretic peptide secretion is stimulated by forskolin and Bay K8644 and inhibited by 8-bromo-cyclic GMP.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Natriuretic Factor; Calcium; Colforsin; Cyclic AMP; Cyclic GMP; Depression, Chemical; Perfusion; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
Oligodendrocyte adhesion activates protein kinase C-mediated phosphorylation of myelin basic protein.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Calcimycin; Cell Adhesion; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Myelin Basic Protein; Neuroglia; Oligodendroglia; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Potentiation of PGE1-induced increase in cyclic AMP by chemotactic peptide and Ca2+ ionophore through calmodulin-dependent processes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Animals; Calcimycin; Calmodulin; Colforsin; Cyclic AMP; Drug Synergism; Female; Guanosine Triphosphate; Guinea Pigs; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin Antagonists; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Bombesin stimulation of gastrin release from canine gastrin cells in primary culture.
Topics: Adenylyl Cyclases; Animals; Bombesin; Calcimycin; Cells, Cultured; Colforsin; Dogs; Gastric Juice; Gastric Mucosa; Gastrins; Protein Kinase C; Receptors, Bombesin; Receptors, Neurotransmitter; Secretory Rate; Somatostatin; Substance P; Tetradecanoylphorbol Acetate | 1987 |
Regulation of insulin release independent of changes of cytosolic Ca2+ concentration.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Colforsin; Cyclic AMP; Cytosol; Digitonin; Epinephrine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Norepinephrine; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Synergism between cellular messengers and agonist combinations in pepsinogen secretion.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bethanechol; Bethanechol Compounds; Bombesin; Calcimycin; Calcium; Cell Communication; Colforsin; Cyclic AMP; Drug Synergism; Esophagus; Fluorescent Antibody Technique; Isoproterenol; L-Lactate Dehydrogenase; Pepsinogens; Protein Kinase C; Rana catesbeiana; Tetradecanoylphorbol Acetate | 1987 |
Effects of activation of protein kinase C on the agonist-induced stimulation and inhibition of cyclic AMP formation in intact human platelets.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Alprostadil; Blood Platelets; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Epinephrine; Humans; Prostaglandin D2; Prostaglandins D; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C-activated calcium channel in the osteoblast-like clonal osteosarcoma cell line UMR-106.
Topics: Calcium; Calcium Channel Blockers; Cell Line; Colforsin; Ion Channels; Kinetics; Osteoblasts; Osteosarcoma; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Development and function of B cells in monolayer islet cells of 3-week-old rat.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Colforsin; Deoxyglucose; Fluorodeoxyglucose F18; Insulin; Insulin Secretion; Iodoacetates; Iodoacetic Acid; Islets of Langerhans; Microscopy, Phase-Contrast; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
Activators of protein kinase C act at a postreceptor site to amplify cyclic AMP production in rat pinealocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adrenergic alpha-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Female; Phenylephrine; Phorbol Esters; Pineal Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1988 |
Locus of inhibitory action of cAMP-dependent protein kinase in the antigen receptor-triggered cytotoxic T lymphocyte activation pathway.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Cholera Toxin; Colforsin; Cyclic AMP; Cytotoxicity, Immunologic; Exocytosis; Lymphocyte Activation; Protein Kinases; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1988 |
Evidence that growth hormone depletion and uncoupling of the regulatory protein of adenylate cyclase (Ns) both contribute to the desensitization of growth hormone responses to growth hormone-releasing factor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Growth Hormone; Growth Hormone-Releasing Hormone; GTP-Binding Proteins; Pituitary Gland, Anterior; Rats; Tetradecanoylphorbol Acetate | 1988 |
Stimulated calcium efflux from fura-2-loaded human platelets.
Topics: Anti-Bacterial Agents; Benzofurans; Blood Platelets; Calcium; Calcium Radioisotopes; Colforsin; Digitonin; Ethers; Fura-2; Humans; In Vitro Techniques; Ion Channels; Ionomycin; Tetradecanoylphorbol Acetate; Thrombin; Time Factors | 1987 |
Characteristics of desensitization of insulin secretion in fully in vitro systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Blood; Colforsin; Cyclic AMP; Fibroblasts; Gene Expression Regulation; Growth Substances; Mice; Mice, Inbred BALB C; Mutation; Oligonucleotides; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transfection | 1988 |
Phorbol esters modulate cyclic AMP accumulation in porcine thyroid cells.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Phorbol 12,13-Dibutyrate; Phorbol Esters; Prostaglandins E; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
Modulation of a human lymphoblastoid B cell line by cyclic AMP. Ig secretion and phosphatidylcholine metabolism.
Topics: 1-Methyl-3-isobutylxanthine; Adjuvants, Immunologic; B-Lymphocytes; Bucladesine; Cell Line, Transformed; Cholera Toxin; Choline; Colforsin; Cyclic AMP; Humans; Immunoglobulins; Phosphatidylcholines; Phosphorus Radioisotopes; Tetradecanoylphorbol Acetate | 1988 |
Cyclic AMP has the ability to influence multiple events during B cell stimulation.
Topics: Antibodies, Monoclonal; Antigens, CD20; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Cell Cycle; Cell Line; Cell Survival; Colforsin; Cyclic AMP; DNA Replication; Humans; Immunoglobulin mu-Chains; In Vitro Techniques; Lymphocyte Activation; Phosphatidylinositols; Tetradecanoylphorbol Acetate | 1988 |
Adenosine 3',5'-cyclic monophosphate (cAMP) inhibits phorbol ester-induced growth of an IL-2-dependent T cell line.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cell Division; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; DNA Replication; Humans; Interleukin-2; Kinetics; Phorbol 12,13-Dibutyrate; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Cyclic AMP potentiates phorbol ester stimulation of tissue plasminogen activator release and inhibits secretion of plasminogen activator inhibitor-1 from human endothelial cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Glycoproteins; Humans; Phorbol Esters; Plasminogen Inactivators; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator | 1988 |
Inhibition of atrial natriuretic peptide secretion by forskolin in noncontracting cultured atrial myocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Atrial Natriuretic Factor; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic GMP; Egtazic Acid; Muscle Contraction; Muscle, Smooth, Vascular; Protein Kinase C; Ryanodine; Sarcoplasmic Reticulum; Secretory Rate; Tetradecanoylphorbol Acetate | 1988 |
Regulation of differentiation of the BC3H1 muscle cell line through cAMP-dependent and -independent pathways.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Creatine Kinase; Cyclic AMP; Fibroblast Growth Factors; Kinetics; Mice; Muscles; Ornithine Decarboxylase; Proto-Oncogenes; Receptors, Cholinergic; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Troponin; Troponin T | 1988 |
Regulation by dibutyryl cyclic AMP of carnosine synthesis in astroglia-rich primary cultures kept in serum-free medium.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Carnosine; Cells, Cultured; Colforsin; Culture Media; Dexamethasone; Dipeptides; Insulin; Mice; Neuroglia; Tetradecanoylphorbol Acetate; Transferrin | 1989 |
Regulation of growth hormone secretion and cyclic AMP metabolism in ovine pituitary cells: interactions involved in activation induced by growth hormone-releasing hormone and phorbol esters.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Growth Hormone; Growth Hormone-Releasing Hormone; Phorbol Esters; Pituitary Gland; Sheep; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Astrocytes regulate GFAP mRNA levels by cyclic AMP and protein kinase C-dependent mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Astrocytes; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Glial Fibrillary Acidic Protein; Humans; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Induction of polyomavirus DNA replication by cyclic AMP and a tumor promoter.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Line, Transformed; Colforsin; Cyclic AMP; Cycloheximide; DNA Replication; Polyomavirus; Protein Biosynthesis; Tetradecanoylphorbol Acetate; Virus Replication | 1988 |
Differentiation of cultured epithelial cells: response to toxic agents.
Topics: Animals; Cell Differentiation; Cell Line; Cells, Cultured; Colforsin; Endometrium; Epidermal Cells; Epithelial Cells; Female; Humans; In Vitro Techniques; Keratins; Methylcholanthrene; Mice; Rats; Receptors, Estrogen; Tetradecanoylphorbol Acetate | 1989 |
Beta-adrenergic and prostanoid inhibition of canine fundic mucosal mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Calcimycin; Colforsin; Concanavalin A; Cyclic AMP; Dinoprostone; Dogs; Enprostil; Epinephrine; Gastric Fundus; Gastric Mucosa; Histamine Release; Isoproterenol; Liver; Mast Cells; Propanolamines; Propranolol; Prostaglandins E, Synthetic; Tetradecanoylphorbol Acetate | 1989 |
Mitogenic activity of phorbol esters and insulin-like growth factor 1 in chemically transformed mouse fibroblasts BP-A31: independent effects and differential sensitivity to inhibition by 3-isobutyl-1-methyl xanthine.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cell Division; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Insulin; Insulin-Like Growth Factor I; Mice; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Somatomedins; Suramin; Tetradecanoylphorbol Acetate; Theophylline | 1989 |
Comparison of the inhibition of insulin release by activation of adenosine and alpha 2-adrenergic receptors in rat beta-cells.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Bucladesine; Colforsin; Dose-Response Relationship, Drug; Epinephrine; Insulin; Ion Channels; Islets of Langerhans; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate | 1989 |
Regulation of osteosarcoma EGF receptor affinity by phorbol ester and cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Colforsin; Cyclic AMP; Epidermal Growth Factor; ErbB Receptors; Humans; Iodine Radioisotopes; Osteosarcoma; Parathyroid Hormone; Tetradecanoylphorbol Acetate | 1989 |
Rapid dephosphorylation of protein kinase C substrates by protein kinase A activators results from inhibition of diacylglycerol release.
Topics: 1-Methyl-3-isobutylxanthine; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport; Bradykinin; Brain; Bucladesine; Colforsin; Cricetinae; Diglycerides; Enzyme Activation; Glycerides; Hybrid Cells; Inositol Phosphates; Kinetics; Mice; Molecular Weight; Neuroblastoma; Phosphates; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Cell Membrane; Colforsin; Cricetinae; Cyclic AMP; Epinephrine; Genes; Glioma; Kinetics; Rats; Receptors, Adrenergic, beta; RNA, Messenger; Tetradecanoylphorbol Acetate; Theophylline; Transcription, Genetic | 1989 |
Identification of an adenosine 3',5'-monophosphate (cAMP)-responsive region in the rat growth hormone gene: evidence for independent and synergistic effects of cAMP and thyroid hormone on gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Chromosome Deletion; Colforsin; Cyclic AMP; Drug Synergism; Gene Expression Regulation; Genes; Growth Hormone; Molecular Sequence Data; Promoter Regions, Genetic; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Theophylline; Thionucleotides; Transcription, Genetic; Triiodothyronine | 1989 |
4-Acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid inhibits adrenocorticotropin secretion from anterior pituitary cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Adrenocorticotropic Hormone; Animals; Calcimycin; Cell Line; Chloride Channels; Chlorides; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Female; Ion Channels; Kinetics; Membrane Proteins; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains; Stilbenes; Tetradecanoylphorbol Acetate | 1989 |
Modulation by intracellular Ca2+ of the hyperpolarization-activated inward current in rabbit single sino-atrial node cells.
Topics: Action Potentials; Animals; Calcium; Cesium; Colforsin; Cyclic AMP; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Rabbits; Sinoatrial Node; Tetradecanoylphorbol Acetate | 1989 |
Inhibitory effect of cyclic AMP on phorbol ester-stimulated production of reactive oxygen metabolites in rat glomeruli.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Colforsin; Cyclic AMP; Kidney Glomerulus; Kinetics; Luminescent Measurements; Male; Oxygen; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Theophylline | 1989 |
The regulation of glucose transporter gene expression by cyclic adenosine monophosphate in NIH3T3 fibroblasts.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anisomycin; Biological Transport, Active; Cholera Toxin; Colforsin; Cyclic AMP; Fibroblasts; Gene Expression Regulation; Glucose; In Vitro Techniques; Monosaccharide Transport Proteins; Protein Kinase C; Rats; RNA; Tetradecanoylphorbol Acetate | 1989 |
Altered release of growth hormone from dispersed adenohypophysial cells of streptozotocin diabetic rats. II. Effects of a phorbol ester and secretagogues which increase cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Somatostatin; Tetradecanoylphorbol Acetate | 1989 |
Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers.
Topics: 1-Methyl-3-isobutylxanthine; Binding Sites; Blotting, Western; Calcimycin; Cell Differentiation; Colforsin; Cyclic AMP; DNA Probes; DNA-Binding Proteins; Gene Expression Regulation; Humans; Plasmids; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic; Transfection; Tretinoin | 1989 |
Fibroblast contractility and actin organization are stimulated by microtubule inhibitors.
Topics: 1-Methyl-3-isobutylxanthine; Actins; Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Cell Movement; Colforsin; Demecolcine; Fibroblasts; Mice; Mice, Inbred Strains; Microscopy, Fluorescence; Microtubules; Nocodazole; Paclitaxel; Photomicrography; Tetradecanoylphorbol Acetate; Vinblastine | 1989 |
Ability of prostaglandin to reduce ethanol injury to dispersed chief cells from guinea pig stomach.
Topics: 16,16-Dimethylprostaglandin E2; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Carbachol; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane Permeability; Colforsin; Ethanol; Female; Gastric Mucosa; Guinea Pigs; L-Lactate Dehydrogenase; Microscopy, Electron; Microscopy, Electron, Scanning; Pepsinogens; Prostaglandins E, Synthetic; Rosaniline Dyes; Sincalide; Tetradecanoylphorbol Acetate | 1989 |
Ca2+-dependent and -independent secretagogue action on gastric mucus secretion in rabbit mucosal explants.
Topics: Acetylcholine; Acetylglucosamine; Animals; Atropine; Calcimycin; Calcium; Calmodulin; Colforsin; Dinoprostone; Gastric Fundus; Gastric Mucosa; Glycoproteins; Histamine; Male; Molecular Weight; Organ Culture Techniques; Pentagastrin; Pyloric Antrum; Rabbits; Sulfonamides; Tetradecanoylphorbol Acetate | 1989 |
Protein kinase C and the stimulation of tissue plasminogen activator release from human endothelial cells. Dependence on the elevation of messenger RNA.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Calcium Channel Blockers; Cells, Cultured; Cloning, Molecular; Colforsin; Cycloheximide; DNA; Endothelium, Vascular; Humans; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator | 1989 |
Calcium and protein kinase C enhance parathyroid hormone- and forskolin-stimulated adenylate cyclase in ROS 17/2.8 cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Cell Line; Colforsin; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Canine enteric submucosal cultures: transmitter release from neurotensin-immunoreactive neurons.
Topics: Animals; Calcimycin; Cells, Cultured; Colforsin; Dogs; Ileum; Immunohistochemistry; Intestinal Mucosa; Neurotensin; Tetradecanoylphorbol Acetate | 1989 |
Growth hormone-releasing factor secretion from fetal hypothalamic cell cultures is modulated by forskolin, phorbol esters, and muscimol.
Topics: Animals; Bicuculline; Cells, Cultured; Chromatography, High Pressure Liquid; Colforsin; Growth Hormone-Releasing Hormone; Hypothalamus; Muscimol; Picrotoxin; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tetradecanoylphorbol Acetate; Verapamil | 1989 |
Regulation of apolipoprotein E biosynthesis by cAMP and phorbol ester in rat ovarian granulosa cells.
Topics: Animals; Apolipoproteins E; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Female; Granulosa Cells; Kinetics; Phorbol Esters; Protein Kinases; Rats; Rats, Inbred Strains; Reference Values; RNA, Messenger; Tetradecanoylphorbol Acetate | 1989 |
Two overlapping sequence motifs within the polyomavirus enhancer are independently the targets of stimulation by both the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the Ha-ras oncogene.
Topics: Animals; Cattle; Colforsin; Cycloheximide; Enhancer Elements, Genetic; Gene Expression Regulation; Genes, ras; Leukemia, Erythroblastic, Acute; Polyomavirus; Regulatory Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Steroidogenesis of porcine granulosa cells from small and medium-sized follicles: effects of follicle-stimulating hormone, forskolin, and adenosine 3,'5'-cyclic monophosphate versus phorbol ester.
Topics: Animals; Bucladesine; Colforsin; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Ovarian Follicle; Progesterone; Protein Kinase C; Steroids; Swine; Tetradecanoylphorbol Acetate | 1989 |
Evidence for a protein kinase C-directed mechanism in the phorbol diester-induced phospholipase D pathway of diacylglycerol generation from phosphatidylcholine.
Topics: Alkaloids; Animals; Bucladesine; Cell Line; Choline; Colforsin; Diglycerides; Embryo, Mammalian; Fibroblasts; Glycerides; Glycerophospholipids; Hydrolysis; Myristic Acid; Myristic Acids; Phorbol 12,13-Dibutyrate; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phospholipases; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Activation of protein kinase C modulates the adenylate cyclase effector system of B-lymphocytes.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Immunoglobulin M; Mice; Mice, Nude; Protein Kinase C; Spleen; Tetradecanoylphorbol Acetate | 1989 |
Interleukin 1 potentiates the secretion of beta-endorphin induced by secretagogues in a mouse pituitary cell line (AtT-20).
Topics: Animals; beta-Endorphin; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Drug Synergism; Enzyme Activation; Interleukin-1; Kinetics; Mice; Pituitary Neoplasms; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1989 |
Signal transduction pathways in the induction of 2',5'-oligoadenylate synthetase gene expression by interferon alpha/beta.
Topics: 2',5'-Oligoadenylate Synthetase; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Northern; Bucladesine; Cells, Cultured; Clone Cells; Colforsin; Enzyme Induction; Gene Expression Regulation; Genes; Interferon Type I; Kinetics; Mice; Mice, Inbred BALB C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1989 |
Interactions between intracellular signals involved in the regulation of 25-hydroxyvitamin D3 metabolism.
Topics: Animals; Bucladesine; Calcifediol; Calcitriol; Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Kidney; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
Negative regulation of human insulin gene expression by the 5'-flanking region in non-pancreatic cells.
Topics: Animals; Base Sequence; Bucladesine; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; DNA Probes; Enhancer Elements, Genetic; Gene Expression Regulation; Glucose; HeLa Cells; Humans; Insulin; Kidney; Nucleic Acid Hybridization; Plasmids; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1989 |
Two different G-proteins mediate neuropeptide Y and bradykinin-stimulated phospholipid breakdown in cultured rat sensory neurons.
Topics: Animals; Bradykinin; Bucladesine; Calcium; Cells, Cultured; Chlorides; Cholera Toxin; Colforsin; Diglycerides; Fluorides; Ganglia, Spinal; GTP-Binding Proteins; Guanine Nucleotides; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Neurons, Afferent; Neuropeptide Y; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Rats; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Phorbol ester inhibits luteinizing hormone-, forskolin-, and dibutyryl cyclic AMP-induced progesterone production in chicken granulosa cells.
Topics: Animals; Bucladesine; Chickens; Colforsin; Female; Granulosa Cells; Luteinizing Hormone; Phorbol Esters; Pregnenolone; Progesterone; Tetradecanoylphorbol Acetate | 1989 |
Phorbol ester impairs melanotropin receptor function and stimulates growth of cultured M2R melanoma cells.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Iodine Radioisotopes; Melanocyte-Stimulating Hormones; Melanoma; Mice; Phorbol Esters; Proteins; Receptors, Pituitary Hormone; Tetradecanoylphorbol Acetate | 1989 |
Cyclic adenosine monophosphate and phorbol ester, like gonadotropin-releasing hormone, stimulate the biosynthesis of luteinizing hormone polypeptide chains in a nonadditive manner.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Luteinizing Hormone; Peptide Biosynthesis; Pituitary Gland, Anterior; Pituitary Hormone-Releasing Hormones; Tetradecanoylphorbol Acetate | 1989 |
Possible roles of cAMP and Ca2+ in the regulation of miracidial transformation in Schistosoma mansoni.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Cholera Toxin; Colforsin; Cyclic AMP; Gallic Acid; Imidazoles; Nicardipine; Quaternary Ammonium Compounds; Schistosoma mansoni; Serotonin; Sodium Chloride; Sulfonamides; Tetradecanoylphorbol Acetate | 1989 |
Selective inactivation by endogenous protein kinase C of human platelet high-affinity GTPase coupled with PAF receptors.
Topics: Adenylyl Cyclases; Blood Platelets; Colforsin; Enzyme Activation; Epinephrine; GTP Phosphohydrolases; Humans; In Vitro Techniques; Phosphoric Monoester Hydrolases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
Effects of forskolin and phorbol-myristate-acetate on cytoskeleton, extracellular matrix and protein phosphorylation in human endothelial cells.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Cytoskeleton; Endothelium, Vascular; Extracellular Matrix; Humans; Phosphorylation; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Vimentin | 1989 |
Phorbol ester regulates the abundance of enkephalin precursor mRNA but not of amyloid beta-protein precursor mRNA in rat testicular peritubular cells.
Topics: Amyloid; Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Enkephalins; Gene Expression Regulation; Male; Protein Precursors; Rats; RNA, Messenger; Testis; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Forskolin stimulates pinealocyte cGMP accumulation. Dramatic potentiation by an alpha 1-adrenergic----[Ca2+]i mechanism involving protein kinase C.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcium; Cations, Divalent; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Female; Phenylephrine; Pineal Gland; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate | 1989 |
Regulation of steroid 17 alpha-hydroxylase in adrenocortical cells in culture.
Topics: Adrenal Cortex; Androgens; Animals; Cattle; Cells, Cultured; Clone Cells; Colforsin; Cyclic AMP; Dehydroepiandrosterone; Fetus; Humans; Kinetics; Second Messenger Systems; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Tetradecanoylphorbol Acetate | 1989 |
Differential activation of the 21-base-pair enhancer element of human T-cell leukemia virus type I by its own trans-activator and cyclic AMP.
Topics: Base Composition; Base Sequence; Cadmium; Cadmium Chloride; Cell Line; Cell Nucleus; Colforsin; Cyclic AMP; Enhancer Elements, Genetic; Gene Expression Regulation; Genes, Viral; HTLV-I Antigens; Human T-lymphotropic virus 1; Humans; Molecular Sequence Data; Plasmids; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transfection | 1989 |
Parathyroid hormone inhibition of Na+/phosphate cotransport in OK cells: requirement of protein kinase C-dependent pathway.
Topics: Alkaloids; Animals; Biological Transport; Carrier Proteins; Cell Line; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Kidney; Opossums; Parathyroid Hormone; Protein Kinase C; Sodium-Phosphate Cotransporter Proteins; Staurosporine; Symporters; Tetradecanoylphorbol Acetate | 1989 |
Neural induction is mediated by cross-talk between the protein kinase C and cyclic AMP pathways.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Bucladesine; Cell Differentiation; Colforsin; Cyclic AMP; Embryonic Induction; Enzyme Induction; Nervous System; Protein Kinase C; Tetradecanoylphorbol Acetate; Xenopus laevis | 1989 |
Effects of the tumor promoter, phorbol 12-myristate, 13-acetate, on the epidermal adenylate cyclase system: evidence for adenylate cyclase-regulation by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Epidermis; Isoquinolines; Osmolar Concentration; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Receptors, Cell Surface; Swine; Tetradecanoylphorbol Acetate | 1989 |
Transmembrane signals mediating adrenocorticotropin release from mouse anterior pituitary cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Diglycerides; Egtazic Acid; Male; Mice; Phosphatidylinositols; Pituitary Gland, Anterior; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1989 |
Facilitative actions of the protein kinase-C effector system on hormonally stimulated adenosine 3',5'-monophosphate production by swine luteal cells.
Topics: Adenylate Cyclase Toxin; Animals; Cells, Cultured; Cholera Toxin; Colforsin; Corpus Luteum; Cyclic AMP; Female; Granulosa Cells; Kinetics; Luteinizing Hormone; Pertussis Toxin; Protein Kinase C; Second Messenger Systems; Swine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Protein kinase-C-induced down-regulation of calcitonin receptors and calcitonin-activated adenylate cyclase in T47D and BEN cells.
Topics: Adenylyl Cyclases; Breast Neoplasms; Calcitonin; Cell Line; Colforsin; Dinitrophenols; Down-Regulation; Enzyme Activation; Female; Humans; Kinetics; Lung Neoplasms; Protein Kinase C; Receptors, Calcitonin; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Dual control of C-reactive protein gene expression by interleukin-1 and interleukin-6.
Topics: C-Reactive Protein; Caffeine; Cell Line; Colforsin; Cycloheximide; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-6; Kanamycin Kinase; Liver; Phosphotransferases; Promoter Regions, Genetic; Protein Biosynthesis; Tetradecanoylphorbol Acetate | 1989 |
Activation of protein kinase C alters the interaction of alpha 2-adrenoceptors and the inhibitory GTP-binding protein (Gi) in human platelets.
Topics: Binding, Competitive; Blood Platelets; Colforsin; Enzyme Activation; Epinephrine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Protein Kinase C; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Yohimbine | 1989 |
Separate regulatory control of apical and basolateral Na+/H+ exchange in renal epithelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Carrier Proteins; Cell Line; Cell Membrane; Colforsin; Enzyme Activation; Epithelium; Homeostasis; Hydrogen-Ion Concentration; Kidney; Kinetics; Protein Kinases; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1989 |
Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways.
Topics: Animals; Base Sequence; Biological Factors; Blotting, Northern; Bucladesine; Calcimycin; Cell Line; Colforsin; Cytokines; DNA-Binding Proteins; DNA-Directed DNA Polymerase; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Interleukin-1; Kinetics; L Cells; Mice; Molecular Sequence Data; Oligonucleotide Probes; Phosphoproteins; Polymerase Chain Reaction; Recombinant Proteins; RNA, Messenger; Second Messenger Systems; Taq Polymerase; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1989 |
Sodium-phosphate cotransport in OK cells: inhibition by PTH and "adaptation" to low phosphate.
Topics: Alkaloids; Animals; Bucladesine; Carrier Proteins; Cell Line; Colforsin; Kidney; Kinetics; Parathyroid Hormone; Peptide Fragments; Phosphates; Sodium-Phosphate Cotransporter Proteins; Staurosporine; Symporters; Teriparatide; Tetradecanoylphorbol Acetate | 1989 |
Activation of protein kinase C sensitizes the cyclic AMP signalling system of T51B rat liver cells.
Topics: Animals; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Liver; Protein Kinase C; Rats; Signal Transduction; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1989 |
Protein kinase C stimulates adenylate cyclase activity in prolactin-secreting rat adenoma (GH4C1) pituicytes by inactivating the inhibitory GTP-binding protein Gi.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkylation; Animals; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Pertussis Toxin; Pituitary Neoplasms; Polymyxin B; Prolactin; Protein Kinase C; Rats; Somatostatin; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
HPLC analysis of somatostatin peptides secreted by a rat pancreatic endocrine cell line (RINT3): stimulation studies.
Topics: Adenoma, Islet Cell; Animals; Cell Line; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Colforsin; Culture Media; Indicators and Reagents; Pancreatic Neoplasms; Peptides; Rats; Somatostatin; Spectrophotometry, Ultraviolet; Tetradecanoylphorbol Acetate | 1989 |
Effect of secretagogues on cytosolic free Ca2+ and insulin release at different extracellular Ca2+ concentrations in the hamster clonal beta-cell line HIT-T15.
Topics: Aminoquinolines; Animals; Calcium; Cell Line; Colforsin; Cricetinae; Fluorescent Dyes; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Potassium; Tetradecanoylphorbol Acetate | 1989 |
Effects of stimulation of adenylate cyclase and protein kinase-C on cultured fetal rat B-cells.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Enzyme Activation; Fetus; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Mitotic Index; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Activation of the thyroid peroxidase gene in human thyroid cells: effect of thyrotrophin, forskolin and phorbol ester.
Topics: Blotting, Northern; Cells, Cultured; Colforsin; Gene Expression Regulation; Graves Disease; Humans; Immunoblotting; Iodide Peroxidase; Oligonucleotide Probes; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroglobulin; Thyroid Gland; Thyrotropin; Transcription, Genetic | 1989 |
The parathyroid hormone-related protein associated with malignancy is secreted by neuroendocrine tumors.
Topics: Colforsin; Hormones, Ectopic; Humans; Hypercalcemia; Neoplasm Proteins; Paraneoplastic Endocrine Syndromes; Parathyroid Hormone; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Age-dependent effects of phorbol ester on adenylate cyclase stimulation by glucagon in liver of female rats.
Topics: Adenylyl Cyclases; Animals; Colforsin; Female; Fetus; Glucagon; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Kinetics; Liver; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Thyrotrophin, forskolin and ionomycin increase cathepsin B mRNA concentrations in rat thyroid cells in culture.
Topics: Actins; Animals; Cathepsin B; Cells, Cultured; Colforsin; Enzyme Induction; Ethers; Ionomycin; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroglobulin; Thyroid Gland; Thyrotropin | 1989 |
Effects of phorbol esters and forskolin on basal and histamine-induced accumulation of inositol phosphates in cultured bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Cattle; Cells, Cultured; Cimetidine; Colforsin; Epinephrine; Histamine; Inositol Phosphates; Kinetics; Norepinephrine; Phorbol Esters; Pyrilamine; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1989 |
Differential regulation of basic protein phosphorylation by calcium phospholipid and cyclic-AMP-dependent protein kinases.
Topics: Animals; Autoradiography; Calcium; Cells, Cultured; Colforsin; Drug Combinations; Enzyme Activation; Hybrid Cells; Molecular Weight; Myelin Proteins; Oligodendroglia; Phospholipids; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinases; Psychosine; Rats; Tetradecanoylphorbol Acetate | 1989 |
Regulation of growth hormone secretion and messenger ribonucleic acid accumulation in human somatotropinoma cells in vitro.
Topics: Adenoma; Adult; Colforsin; Female; Growth Hormone; Humans; Male; Pituitary Neoplasms; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1989 |
Secretion of corticotropin-releasing factor from cultured rat hypothalamic cells: effects of catecholamines.
Topics: Animals; Animals, Newborn; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Hypothalamus; Isoproterenol; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1989 |
Similarities and differences in phorbol ester- and luteinizing-hormone-induced desensitization of rat tumour Leydig-cell adenylate cyclase.
Topics: Adenosine; Adenylyl Cyclases; Animals; Cholera Toxin; Colforsin; Cyclic AMP; In Vitro Techniques; Leydig Cell Tumor; Luteinizing Hormone; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1987 |
Newly synthesized protein secretion in rat lacrimal gland: post-second messenger synergism.
Topics: Animals; Bucladesine; Calcimycin; Carbachol; Colforsin; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lacrimal Apparatus; Male; Papaverine; Proteins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1987 |
Antibody-induced cAMP accumulation in splenocytes from athymic nude mice.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Colforsin; Cyclic AMP; Diglycerides; DNA Replication; Enzyme Activation; Mice; Mice, Nude; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Receptors, Antigen, B-Cell; Spleen; Tetradecanoylphorbol Acetate | 1987 |
Desensitisation of LH-stimulated cyclic AMP accumulation in isolated bovine luteal cells--effect of phorbol ester.
Topics: Animals; Cattle; Cholera Toxin; Chorionic Gonadotropin; Colforsin; Corpus Luteum; Cyclic AMP; Female; In Vitro Techniques; Luteinizing Hormone; Progesterone; Protein Kinase C; Radioligand Assay; Receptors, Gonadotropin; Tetradecanoylphorbol Acetate | 1987 |
Aluminum fluoride induces phosphatidylinositol turnover, elevation of cytoplasmic free calcium, and phosphorylation of the T cell antigen receptor in murine T cells.
Topics: Aluminum; Aluminum Compounds; Animals; Antigens; Calcium; Colforsin; Cyclic AMP; Cytosol; Egtazic Acid; Fluorides; Membrane Lipids; Mice; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Sodium Fluoride; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Effect of secretagogues on cytoplasmic free calcium in alveolar type II epithelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminoquinolines; Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Cytoplasm; Enzyme Activation; Epithelium; Ethers; Fluorescent Dyes; Ionomycin; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Terbutaline; Tetradecanoylphorbol Acetate | 1987 |
Distinct mechanisms for two amplification systems of insulin release.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Female; In Vitro Techniques; Insulin; Islets of Langerhans; Membrane Potentials; Mice; Protein Kinases; Rubidium; Tetradecanoylphorbol Acetate; Tolbutamide | 1987 |
Mechanisms of TSH release: studies with forskolin, phorbol ester and A23187.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Female; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thyrotropin | 1987 |
Phorbol esters induce two distinct changes in GH3 pituitary cell adenylate cyclase activity.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Enzyme Activation; Guanylyl Imidodiphosphate; Manganese; Pituitary Neoplasms; Protein Kinase C; Rats; Sodium Fluoride; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1988 |
Dual regulation of 3 beta-hydroxysteroid dehydrogenase, 17 alpha-hydroxylase, and dehydroepiandrosterone sulfotransferase by adenosine 3',5'-monophosphate and activators of protein kinase C in cultured human adrenocortical cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Angiotensin II; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Induction; Epidermal Growth Factor; Fibroblast Growth Factors; Humans; Kinetics; Protein Kinase C; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Sulfotransferases; Sulfurtransferases; Tetradecanoylphorbol Acetate | 1988 |
Rat neuropeptide Y precursor gene expression. mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester.
Topics: Animals; Base Sequence; Brain Chemistry; Calcimycin; Cell Line; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dexamethasone; Gene Expression Regulation; Glucocorticoids; Humans; Molecular Sequence Data; Neuropeptide Y; Phorbol Esters; Protein Precursors; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured | 1988 |
Effect of Graves' IgG on gene transcription in human thyroid cell cultures. Thyroglobulin gene activation.
Topics: Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation; Graves Disease; Humans; Immunoglobulin G; Nucleic Acid Hybridization; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroglobulin; Thyroid Gland; Transcription, Genetic; Transcriptional Activation | 1988 |
Effect of phorbol esters on the hormonal responsiveness of isolated white fat cells.
Topics: Adipose Tissue; Animals; Colforsin; Cyclic AMP; Dinoprostone; Epinephrine; Fatty Acids; In Vitro Techniques; Isoproterenol; Lipolysis; Male; Phenylisopropyladenosine; Phospholipids; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Adenosine 3',5'-monophosphate-dependent loss of growth hormone binding in rat adipocytes.
Topics: Adipose Tissue; Animals; Bucladesine; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Epinephrine; Growth Hormone; In Vitro Techniques; Kinetics; Lipolysis; Male; Pertussis Toxin; Rats; Receptors, Somatotropin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Phorbol ester modulation of cyclic AMP accumulation in a primary culture of rat aortic smooth muscle cells.
Topics: Adenylate Cyclase Toxin; Animals; Aorta; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Isoproterenol; Muscle, Smooth, Vascular; Pertussis Toxin; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Arachidonic acid and cyclic adenosine monophosphate stimulation of c-fos expression by a pathway independent of phorbol ester-sensitive protein kinase C.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Colforsin; Cyclic AMP; Mice; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Control of human T-lymphocyte interleukin-2 production by a cAMP-dependent pathway.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Adolescent; Adult; Aged; Azides; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Immunologic; Female; Humans; Immunosuppressive Agents; Interleukin-1; Interleukin-2; Lymphocyte Activation; Male; Middle Aged; Phosphorylation; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Arginine vasopressin increases cellular free calcium concentration and adenosine 3',5'-monophosphate production in rat renal papillary collecting tubule cells in culture.
Topics: Animals; Arginine Vasopressin; Bucladesine; Calcium; Calcium Radioisotopes; Cells, Cultured; Colforsin; Cyclic AMP; Egtazic Acid; Glucagon; Kidney Tubules; Kidney Tubules, Collecting; Kinetics; Male; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Inhibition by iodide of iodide binding to proteins: the "Wolff-Chaikoff" effect is caused by inhibition of H2O2 generation.
Topics: Animals; Bucladesine; Carbachol; Colforsin; Dogs; Ethers; Horseradish Peroxidase; Hydrogen Peroxide; In Vitro Techniques; Iodides; Ionomycin; Kinetics; Models, Biological; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1988 |
Characterization and possible mechanisms of alpha 2-adrenergic receptor-mediated sensitization of forskolin-stimulated cyclic AMP production in HT29 cells.
Topics: Adenocarcinoma; Adenylate Cyclase Toxin; Blood Platelets; Carrier Proteins; Cell Line; Colforsin; Colonic Neoplasms; Cyclic AMP; Cycloheximide; Enzyme Activation; Humans; Kinetics; Norepinephrine; Pertussis Toxin; Protein Kinase C; Receptors, Adrenergic, alpha; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1988 |
Cyclic AMP and phorbol esters interact synergistically to regulate expression of the chorionic gonadotropin genes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Drug Synergism; Gene Expression Regulation; Humans; Phorbol Esters; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1988 |
Inhibition by cyclic AMP of phorbol ester-potentiated norepinephrine release from guinea pig brain cortical synaptosomes.
Topics: Alkaloids; Animals; Bucladesine; Carbazoles; Cerebral Cortex; Colforsin; Cyclic AMP; Enzyme Activation; Female; Guinea Pigs; Indoles; Male; Norepinephrine; Polymyxin B; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Staurosporine; Synaptosomes; Tetradecanoylphorbol Acetate | 1988 |
Activators of protein kinase C enhance cyclic AMP accumulation in cerebral cortical and diencephalic neurons in primary culture.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Diencephalon; Diglycerides; Glycerides; Protein Kinase C; Rats; Second Messenger Systems; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1988 |
Interactions of protein kinase C with receptor- and non-receptor-mediated cyclic AMP generation in swine granulosa cells.
Topics: Animals; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Female; Follicle Stimulating Hormone; Granulosa Cells; GTP-Binding Proteins; Protein Kinase C; Receptors, Cell Surface; Signal Transduction; Swine; Tetradecanoylphorbol Acetate | 1988 |
Regulation of cytosolic calcium by cAMP and cGMP in freshly isolated smooth muscle cells from bovine trachea.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzofurans; Calcium; Calcium Channel Blockers; Carbachol; Cattle; Cholera Toxin; Colforsin; Cyclic AMP; Cyclic GMP; Cytosol; Fura-2; Isoproterenol; Muscle, Smooth; Pertussis Toxin; Tetradecanoylphorbol Acetate; Trachea; Virulence Factors, Bordetella | 1988 |
Vasoactive intestinal peptide receptor/adenylate cyclase system: differences between agonist- and protein kinase C-mediated desensitization and further evidence for receptor internalization.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Alkaloids; Animals; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Isoquinolines; Peptide PHI; Piperazines; Protein Kinase C; Receptors, Gastrointestinal Hormone; Receptors, Vasoactive Intestinal Peptide; Staurosporine; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1988 |
Calcitonin gene-related peptide and calcitonin secretion from a human medullary thyroid carcinoma cell line: effects of ionomycin, phorbol ester and forskolin.
Topics: Calcitonin; Calcitonin Gene-Related Peptide; Calcium; Carcinoma; Cell Line; Colforsin; Cyclic AMP; Ethers; Humans; Ionomycin; Neoplasm Proteins; Neuropeptides; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Tumor Cells, Cultured | 1988 |
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzyme Activation; Female; Glucagon; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hypothyroidism; Isoproterenol; Liver; Pertussis Toxin; Propranolol; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Urea; Vasopressins; Virulence Factors, Bordetella | 1988 |
Control of pepsinogen synthesis and secretion in primary monolayer cultures of canine gastric chief cells.
Topics: Animals; Bucladesine; Carbachol; Cells, Cultured; Colforsin; Culture Media; Dogs; Gastric Mucosa; In Vitro Techniques; Pepsinogens; Sincalide; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors; Vasoactive Intestinal Peptide | 1988 |
Two adjacent promoter elements mediate nerve growth factor activation of the c-fos gene and bind distinct nuclear complexes.
Topics: Animals; Base Sequence; Cell Line; Colforsin; Cyclic AMP; Epidermal Growth Factor; Heat-Shock Proteins; Humans; Molecular Sequence Data; Nerve Growth Factors; Promoter Regions, Genetic; Proto-Oncogenes; Rats; Tetradecanoylphorbol Acetate | 1988 |
PGE2-induced cyclic AMP accumulation in human CD4+ T cells is strongly enhanced during the CD2-mediated activatory process.
Topics: Antibodies, Monoclonal; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Humans; Isoproterenol; Lymphocyte Activation; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1988 |
Control of parathyroid hormone-degrading activity in the opossum kidney cell: possible involvement of protein kinase C.
Topics: Animals; Bucladesine; Calcimycin; Cell Line; Chromatography, High Pressure Liquid; Colforsin; Diglycerides; Enzyme Activation; Humans; Kidney; Opossums; Parathyroid Hormone; Peptide Fragments; Phorbol Esters; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1988 |
Effect of forskolin on beta-adrenergic hyporesponsiveness in skin.
Topics: Animals; Colforsin; Cyclic AMP; Female; Isoproterenol; Keratinocytes; Mice; Mice, Inbred C3H; Psoriasis; Receptors, Adrenergic, beta; Skin; Tetradecanoylphorbol Acetate | 1988 |
Phorbol esters stimulate somatostatin release from cultured cells.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Dogs; Drug Synergism; Egtazic Acid; Enzyme Activation; Gastric Mucosa; Phorbol Esters; Protein Kinase C; Somatostatin; Tetradecanoylphorbol Acetate | 1986 |
Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol esters. Withdrawal of GTP-dependent inhibition.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Cell Line; Chlorides; Colforsin; Cyclic AMP; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Isoproterenol; Kinetics; Lymphoma; Magnesium; Magnesium Chloride; Manganese; Manganese Compounds; Mathematics; Pertussis Toxin; Phorbol Esters; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Phorbol esters enhance neurotransmitter-stimulated cyclic AMP production in rat brain slices.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Isoproterenol; Male; Molecular Weight; Neurotransmitter Agents; Phorbol Esters; Phosphorylation; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tissue Distribution; Vasoactive Intestinal Peptide | 1986 |
Tyrosine hydroxylase is activated and phosphorylated on different sites in rat pheochromocytoma PC12 cells treated with phorbol ester and forskolin.
Topics: Adrenal Gland Neoplasms; Animals; Cell Line; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Ethers; Ionomycin; Peptide Mapping; Pheochromocytoma; Phosphopeptides; Phosphorylation; Rats; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine 3-Monooxygenase | 1987 |
The potentiating effects of phorbol ester on ACTH-, cholera toxin-, and forskolin-induced cAMP production by cultured bovine adrenal cells is not mediated by the inactivation of alpha subunit of Gi protein.
Topics: Adenosine Diphosphate Ribose; Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Cattle; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Drug Synergism; GTP-Binding Proteins; Lymphoma; Membrane Proteins; Somatostatin; Tetradecanoylphorbol Acetate | 1987 |
Mechanisms for the stimulatory and inhibitory effects of carbamoylcholine on canine gastric D-cells.
Topics: Animals; Bucladesine; Carbachol; Colforsin; Dogs; Gastric Mucosa; GTP-Binding Proteins; Pertussis Toxin; Phosphatidylinositols; Receptors, Muscarinic; Secretory Rate; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Biosynthesis of somatostatin in canine fundic D cells.
Topics: Animals; Cells, Cultured; Colforsin; Cycloheximide; Cysteine; Dogs; Gastric Mucosa; Molecular Weight; Pertussis Toxin; Protein Processing, Post-Translational; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Interleukin-2 receptor-inducing factor(s) in adult T cell leukemia.
Topics: Antibodies, Monoclonal; Colforsin; Deltaretrovirus Infections; Gene Expression Regulation; Genes; Humans; Interleukin-2; Lymphokines; Mitogens; Promoter Regions, Genetic; Receptors, Immunologic; Receptors, Interleukin-2; Recombinant Fusion Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Control of gastrin release in cultured gastrinoma-derived G cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adult; Cells, Cultured; Chromaffin System; Colforsin; Enterochromaffin Cells; Female; Gastrins; Humans; Immunohistochemistry; Liver Neoplasms; Phorbol Esters; Radioimmunoassay; Secretin; Somatostatin; Tetradecanoylphorbol Acetate; Zollinger-Ellison Syndrome | 1988 |
Phorbol esters and thyroliberin have distinct actions regarding stimulation of prolactin secretion and activation of adenylate cyclase in rat pituitary tumour cells (GH4C1 cells).
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Diglycerides; Enzyme Activation; Guanylyl Imidodiphosphate; Phorbol Esters; Pituitary Neoplasms; Polymyxin B; Prolactin; Rats; Somatostatin; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1988 |
Pertussis toxin-sensitive cholinergic inhibition of somatostatin release from canine D-cells.
Topics: Animals; Bucladesine; Calcimycin; Carbachol; Cells, Cultured; Colforsin; Dogs; Epinephrine; Gastric Fundus; Gastric Mucosa; Kinetics; Pertussis Toxin; Reference Values; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Actions of pertussis toxin on the inhibitory effects of dopamine and somatostatin on prolactin and growth hormone release from ovine anterior pituitary cells.
Topics: Adenylate Cyclase Toxin; Animals; Cells, Cultured; Colforsin; Dopamine; Growth Hormone; GTP-Binding Proteins; Pertussis Toxin; Pituitary Gland, Anterior; Prolactin; Signal Transduction; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
The influence of activating hormones on human platelet membrane Ca2+-ATPase activity.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Calcimycin; Calcium-Transporting ATPases; Cell Membrane; Colforsin; Ethers; Humans; Ionomycin; Kinetics; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1986 |
Activation of distinct second messenger systems in anterior pituitary corticotrophic tumor cells alters the phosphorylation states of both shared and distinct cytosolic proteins.
Topics: Adenylyl Cyclases; Animals; beta-Endorphin; Cell Line; Colforsin; Cytosol; Endorphins; Enzyme Activation; Kinetics; Mice; Neoplasm Proteins; Phosphorus Radioisotopes; Phosphorylation; Pituitary Neoplasms; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Secretion and biosynthesis of atrial natriuretic factor by cultured adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Colforsin; Gene Expression Regulation; Protein Precursors; Protein Processing, Post-Translational; Secretory Rate; Tetradecanoylphorbol Acetate | 1988 |
Insulin release independent of a rise in cytosolic free Ca2+ by forskolin and phorbol ester.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Digitonin; Diterpenes; Insulin; Islets of Langerhans; Male; Phorbols; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1985 |
Phorbol ester stimulates catecholamine synthesis in isolated bovine adrenal medullary cells.
Topics: Adrenal Medulla; Animals; Bucladesine; Calcium; Carbachol; Catecholamines; Cattle; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; In Vitro Techniques; Phorbols; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tyrosine | 1985 |
Interactions between cyclic AMP- and phorbol ester-dependent phosphorylation systems in S49 mouse lymphoma cells.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Drug Synergism; Lymphoma; Mice; Phorbols; Phosphorylation; Proteins; Tetradecanoylphorbol Acetate | 1985 |
Differences in the mode of action of 1-oleoyl-2-acetyl-glycerol and phorbol ester in platelet activation.
Topics: Adenylyl Cyclases; Apyrase; Blood Platelets; Blood Proteins; Colforsin; Cyclic AMP; Diglycerides; Glycerides; Humans; Kinetics; Papaverine; Phorbols; Phosphorylation; Platelet Aggregation; Tetradecanoylphorbol Acetate | 1985 |
Phorbol ester stimulates progesterone production by isolated bovine luteal cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cattle; Cholera Toxin; Chorionic Gonadotropin; Colforsin; Corpus Luteum; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Female; Kinetics; Luteal Cells; Phorbols; Progesterone; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
The protein kinase C activator phorbol-12-myristate-13-acetate enhances cyclic AMP accumulation in pheochromocytoma cells.
Topics: 2-Chloroadenosine; Adenosine; Adrenal Gland Neoplasms; Animals; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Pheochromocytoma; Phorbols; Phosphatidylinositols; Protein Kinase C; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
Dopamine inhibits prolactin release when cyclic adenosine 3',5'-monophosphate levels are elevated.
Topics: Animals; Calcimycin; Colforsin; Cyclic AMP; Dopamine; Female; Fluorescent Antibody Technique; Microscopy, Fluorescence; Pituitary Neoplasms; Prolactin; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1986 |
Regulation of thyroxine 5'-deiodinase by thyroid hormones and activators of protein kinase C in GH4C1 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Cell Line; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Hypothyroidism; Iodide Peroxidase; Phorbol Esters; Pituitary Neoplasms; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thyroid Hormones; Thyrotropin-Releasing Hormone; Thyroxine; Trifluoperazine; Triiodothyronine; Triiodothyronine, Reverse | 1986 |
Potentiation of prostaglandin E1-stimulated cAMP formation by 12-O-tetradecanoylphorbol-13-acetate in BALB/c mouse 3T3 cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Kinetics; Mice; Phorbols; Tetradecanoylphorbol Acetate | 1986 |
Diminished pituitary responsiveness to growth hormone-releasing factor in aging male rats.
Topics: Aging; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Growth Hormone; Growth Hormone-Releasing Hormone; Kinetics; Male; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Activation of protein kinase C potentiates cyclic AMP production and stimulates steroidogenesis in differentiated ovarian granulosa cells.
Topics: Animals; Cell Differentiation; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Female; Granulosa Cells; Pituitary Hormone-Releasing Hormones; Progesterone; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1986 |
Activation of two different but complementary biochemical pathways stimulates release of hypothalamic luteinizing hormone-releasing hormone.
Topics: Animals; Colforsin; Cyclic AMP; Cyclooxygenase Inhibitors; Diglycerides; Dinoprostone; Drug Interactions; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Indomethacin; Norepinephrine; Prostaglandins E; Protein Kinase C; Rats; Secretory Rate; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1986 |
Regulation of magnesium but not calcium transport by phorbol ester.
Topics: Animals; Biological Transport, Active; Calcium; Cell Line; Colforsin; Cyclic AMP; Isoproterenol; Kinetics; Lymphoma; Magnesium; Phorbols; Phosphorylation; Tetradecanoylphorbol Acetate | 1986 |
Phorbol ester-induced augmentation and inhibition of epinephrine-stimulated adenylate cyclase in S49 lymphoma cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Cells, Cultured; Colforsin; Cyclic AMP; Epinephrine; Guanylyl Imidodiphosphate; Lymphoma; Pertussis Toxin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Effects of prolonged phorbol ester exposure on ACTH secretion from mouse pituitary tumor cells.
Topics: Adrenocorticotropic Hormone; Animals; Cells, Cultured; Colforsin; Mice; Pituitary Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Antibody binding to CD5 (Tp67) and Tp44 T cell surface molecules: effects on cyclic nucleotides, cytoplasmic free calcium, and cAMP-mediated suppression.
Topics: Antibodies, Monoclonal; Antigen-Antibody Reactions; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Bucladesine; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Humans; Interleukin-1; Lymphocyte Activation; Membrane Proteins; Monocytes; Nucleotides, Cyclic; Prostaglandins E; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Effects of dehydrouramil on protein phosphorylation and insulin secretion in rat islets of Langerhans.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Calmodulin; Colforsin; Cyclic AMP; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Protein Kinases; Proteins; Pyrimidinones; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
4 beta-Phorbol 12-myristate 13-acetate attenuates the glucagon-induced increase in cytoplasmic free Ca2+ concentration in isolated rat hepatocytes.
Topics: Aminoquinolines; Animals; Bucladesine; Calcium; Colforsin; Fluorescent Dyes; Glucagon; In Vitro Techniques; Liver; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of human B cell responsiveness by prostaglandin E2.
Topics: B-Lymphocytes; Cell Cycle; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Depression, Chemical; Dinoprost; Dinoprostone; Ethers; Humans; Ionomycin; Lymphocyte Activation; Lymphokines; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate; Vinblastine | 1987 |
Tumor promoters as probes of protein kinase C in dog thyroid cell: inhibition of the primary effects of carbamylocholine and reproduction of some distal effects.
Topics: Alprostadil; Animals; Carbachol; Colforsin; Cyclic AMP; Diglycerides; Dogs; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1987 |
Enhancement of cmyc mRNA concentration in dog thyrocytes initiating DNA synthesis in response to thyrotropin, forskolin, epidermal growth factor and phorbol myristate ester.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Dogs; Epidermal Growth Factor; Nucleic Acid Hybridization; Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1986 |
Suppression of human lymphocyte responsiveness by forskolin: reversal by 12-O-tetradecanoyl phorbol 13-acetate, diacylglycerol and ionomycin.
Topics: Colforsin; Cyclic AMP; Diglycerides; Ethers; Humans; In Vitro Techniques; Ionomycin; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Mitogens; Tetradecanoylphorbol Acetate | 1987 |
Sensitization of adrenocortical cell adenylate cyclase activity to ACTH by angiotensin II and activators of protein kinase C.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenal Cortex; Adrenocorticotropic Hormone; Angiotensin II; Animals; Cattle; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Pertussis Toxin; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Role of second messengers in the regulation of glucagon secretion from isolated rat islets of Langerhans.
Topics: Animals; Arginine; Calcimycin; Calcium; Colforsin; Cyclic AMP; Diglycerides; Drug Interactions; Glucagon; Glycerides; Islets of Langerhans; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Trifluoperazine | 1987 |
Multiple effects of phorbol esters on hormone-sensitive adenylate cyclase activity in S49 lymphoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Lymphoma; Phorbol Esters; Protein Kinase C; Receptors, Adrenergic, beta; Sodium Fluoride; Temperature; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C activators and bradykinin selectively inhibit vasopressin-stimulated cAMP synthesis in MDCK cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bradykinin; Cell Line; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Glucagon; Isoquinolines; Piperazines; Prostaglandins E; Protein Kinase C; Tetradecanoylphorbol Acetate; Vasopressins | 1987 |
Regulation of protein kinase C by cyclic adenosine 3':5'-monophosphate and a tumor promoter in skeletal myoblasts.
Topics: Animals; Avian Sarcoma Viruses; Bucladesine; Cell Line; Cell Membrane; Cell Transformation, Viral; Colforsin; Cyclic AMP; Cytosol; Isoproterenol; Muscles; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1987 |
Interactions among lithium, calcium, diacylglycerides, and phorbol esters in the regulation of adrenocorticotropin hormone release from AtT-20 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Calcium; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Diglycerides; Dose-Response Relationship, Drug; Drug Interactions; Glycerides; Inositol Phosphates; Lithium; Mice; Phorbol Esters; Pituitary Gland, Anterior; Pituitary Neoplasms; Potassium; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
Inhibition of receptor-mediated stimulation of cyclic AMP accumulation in neuroblastoma-hybrid NCB-20 cells by a phorbol ester.
Topics: Adenylyl Cyclases; Animals; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Dinoprostone; Dopamine; GTP-Binding Proteins; Hybrid Cells; Mice; Neuroblastoma; Phosphorylation; Prostaglandins E; Protein Kinase C; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1987 |
Effect of secretagogues on cytosolic free Ca2+ and insulin release in the hamster clonal beta-cell line HIT-T15.
Topics: Aminoquinolines; Animals; Calcium; Carbachol; Cell Line; Cells, Cultured; Clone Cells; Colforsin; Cricetinae; Dose-Response Relationship, Drug; Fluorescent Dyes; Glucose; Insulin; Islets of Langerhans; Potassium; Tetradecanoylphorbol Acetate; Verapamil | 1988 |
Distinct effect of forskolin and interferon-gamma on cell proliferation and regulation of histocompatibility antigen expression in hematopoietic cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Cycle; Cell Line; Colforsin; Hematopoietic Stem Cells; Histocompatibility Antigens Class II; HLA Antigens; HLA-DR Antigens; Humans; Interferon-gamma; Tetradecanoylphorbol Acetate | 1986 |
The cellular basis of the calcium dependence of GnRH-stimulated gonadotropin release from frog, Rana pipiens, pituitaries.
Topics: Animals; Benzimidazoles; Calcimycin; Calcium; Colchicine; Colforsin; Cytochalasin B; Cytoskeleton; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Nocodazole; Pimozide; Pituitary Gland; Rana pipiens; Secretory Rate; Tetradecanoylphorbol Acetate; Time Factors; Trifluoperazine | 1986 |
Stimulation by vasoactive intestinal polypeptide of catecholamine synthesis in isolated bovine adrenal chromaffin cells. Possible involvement of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Medulla; Animals; Calcium; Carbachol; Catecholamines; Cattle; Colforsin; Dihydroxyphenylalanine; In Vitro Techniques; Isoquinolines; Piperazines; Tetradecanoylphorbol Acetate; Tyrosine; Vasoactive Intestinal Peptide | 1987 |
Downregulation of c-myc RNA is not a prerequisite for reduced cell proliferation, but is associated with G1 arrest in B-lymphoid cell lines.
Topics: B-Lymphocytes; Cell Cycle; Cell Division; Cell Line; Colforsin; Growth Substances; Humans; Interferon-gamma; Interphase; Leukemia, Lymphoid; Proto-Oncogenes; Recombinant Proteins; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1987 |
Evidence that diminished pituitary responsivity to GHRF is secondary to intracellular GH pool depletion.
Topics: Animals; Calcium; Colforsin; Extracellular Space; Growth Hormone; Growth Hormone-Releasing Hormone; Intracellular Membranes; Male; Osmolar Concentration; Pituitary Gland; Potassium Chloride; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Oxytocin activates the inositol-phospholipid-protein kinase-C system and stimulates prostaglandin production in human amnion cells.
Topics: Amnion; Calcium; Cells, Cultured; Colforsin; Dinoprostone; Egtazic Acid; Epithelium; Humans; Inositol Phosphates; Isoproterenol; Oxytocin; Prostaglandins E; Protein Kinase C; Reference Values; Ritodrine; Sugar Phosphates; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
The alpha 1-adrenergic transduction system in hamster brown adipocytes. Release of arachidonic acid accompanies activation of phospholipase C.
Topics: Adipose Tissue, Brown; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Colforsin; Cricetinae; Cyclohexanones; Egtazic Acid; Enzyme Activation; In Vitro Techniques; Inositol Phosphates; Insulin; Isoproterenol; Lipid Metabolism; Male; Phenylephrine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Forskolin and 12-0-tetradecanoylphorbol-13-acetate mimic thyrotropin-stimulated protein iodination in mouse thyroid.
Topics: Adenylyl Cyclases; Animals; Colforsin; Diterpenes; Female; Iodine; Mice; Phorbols; Protein Kinase C; Protein Kinases; Proteins; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1985 |
Lineage-specific regulation of the vasoactive intestinal peptide gene in neuroblastoma cells is conferred by 5.2 kilobases of 5'-flanking sequence.
Topics: Base Sequence; Cell Line; Chromosome Deletion; Colforsin; Enhancer Elements, Genetic; Humans; Molecular Sequence Data; Molecular Weight; Neuroblastoma; Plasmids; Tetradecanoylphorbol Acetate; Transfection; Vasoactive Intestinal Peptide | 1988 |
Forskolin and phorbol esters decrease the same K+ conductance in cultured oligodendrocytes.
Topics: Animals; Cells, Cultured; Colforsin; Electric Conductivity; Electrophysiology; Membrane Potentials; Neuroglia; Oligodendroglia; Phorbol Esters; Potassium; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1988 |
The role of secondary messengers in the regulation of lipid peroxidation in rat liver microsomes.
Topics: Animals; Colforsin; Lipid Peroxidation; Liver; Male; Microsomes, Liver; Polymyxin B; Rats; Rats, Inbred Strains; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1988 |
Possible involvement of diacylglycerol-activated, Ca2+-dependent protein kinase in glucose memory of the rat pancreatic B-cell.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Colforsin; Enzyme Activation; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Male; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Sulfonamides; Tetradecanoylphorbol Acetate | 1988 |
A re-assessment of the role of protein kinase C in glucose-stimulated insulin secretion.
Topics: Animals; Colforsin; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Phosphorylation; Protein Kinase C; Proteins; Rats; Rats, Inbred Strains; Sucrose; Tetradecanoylphorbol Acetate | 1987 |
Rat fetal islets as a useful model for the study of insulin release failure.
Topics: Animals; Colforsin; Culture Techniques; Disease Models, Animal; Female; Fetus; Gliclazide; Insulin; Insulin Secretion; Islets of Langerhans; Pregnancy; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Phorbol ester prevents the thyroid-stimulating-hormone-induced but not the forskolin-induced decrease of cAMP-dependent protein kinase activity in thyroid cell cultures.
Topics: Animals; Cells, Cultured; Colforsin; Phosphorylation; Protein Kinase C; Protein Kinases; Substrate Specificity; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors | 1988 |
A role for protein kinase C in astrocyte glycogen metabolism.
Topics: Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Colforsin; Deoxyglucose; Diglycerides; Glycogen; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1988 |
Morphological alterations in endothelial cells from human aorta and umbilical vein induced by forskolin and phorbol 12-myristate 13-acetate: a synergistic action of adenylate cyclase and protein kinase C activators.
Topics: Adenylyl Cyclases; Aorta; Cells, Cultured; Colforsin; Culture Techniques; Drug Synergism; Endothelium; Enzyme Activation; Humans; Protein Kinase C; Tetradecanoylphorbol Acetate; Umbilical Veins | 1986 |
Regulated expression of the platelet-derived growth factor A chain gene in microvascular endothelial cells.
Topics: Cells, Cultured; Colforsin; Endothelium, Vascular; Gene Expression Regulation; Humans; Peptides; Platelet-Derived Growth Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Thrombin; Transforming Growth Factors | 1987 |
Influence of a tumor promoting phorbol ester on the metabolism of 25-hydroxyvitamin D3.
Topics: 24,25-Dihydroxyvitamin D 3; Animals; Calcifediol; Calcitriol; Cells, Cultured; Chickens; Colforsin; Dihydroxycholecalciferols; Dose-Response Relationship, Drug; Kidney; Parathyroid Hormone; Tetradecanoylphorbol Acetate; Vitamin D Deficiency | 1986 |
Phorbol ester effect on the hydrosmotic response to vasopressin in frog skin.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine Vasopressin; Colforsin; In Vitro Techniques; Naproxen; Osmolar Concentration; Rana esculenta; Skin; Tetradecanoylphorbol Acetate; Vasopressins | 1987 |
TPA inhibits the synthesis of androgens and cortisol and enhances the synthesis non-17 alpha-hydroxylated steroids in cultured human adrenocortical cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Adrenal Cortex Hormones; Androgens; Cells, Cultured; Colforsin; Humans; Hydrocortisone; Kinetics; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Tetradecanoylphorbol Acetate | 1987 |
Restoration of the A cell response to glucose in isolated rat islets of Langerhans.
Topics: Animals; Arginine; Colforsin; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Potentiators of insulin secretion modulate Ca2+ sensitivity in rat pancreatic islets.
Topics: Acetylcholine; Animals; Calcium; Colforsin; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Effects of histamine on the metabolism of isolated rat hepatocytes: roles of H1- and H2-histamine receptors.
Topics: Animals; Calcium; Colforsin; Gluconeogenesis; Histamine; Hypothyroidism; Liver; Liver Glycogen; Pertussis Toxin; Rats; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Tetradecanoylphorbol Acetate; Urea; Virulence Factors, Bordetella | 1987 |
Kinetic analysis of 'rapid onset' neurite formation in NG108-15 cells reveals a dual role for substratum-bound laminin.
Topics: Adenosine; Cell Differentiation; Cell Line; Colforsin; Cycloheximide; Deoxyadenosines; Laminin; Neurons; Tetradecanoylphorbol Acetate; Thionucleosides | 1987 |
Synthetic diacylglycerols induce a rise of quin2-detectable free intracellular calcium in human platelets.
Topics: Aminoquinolines; Blood Platelets; Calcium; Colforsin; Diglycerides; Enzyme Activation; Fluorescent Dyes; Glycerides; Humans; Protein Kinase C; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1987 |
Improved clonal and nonclonal growth of human, rat and bovine adrenocortical cells in culture.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Animals; Blood Physiological Phenomena; Blood Substitutes; Cattle; Cell Division; Cells, Cultured; Clone Cells; Colforsin; Culture Media; Culture Techniques; Fibronectins; Growth Substances; Horses; Humans; Organic Chemicals; Tetradecanoylphorbol Acetate | 1987 |
Phorbol ester: effect on intraocular pressure, adenylate cyclase, and protein kinase in the rabbit eye.
Topics: Adenylyl Cyclases; Animals; Aqueous Humor; Calcium; Carcinogens; Ciliary Body; Colforsin; Intraocular Pressure; Phorbol Esters; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1987 |
Phorbol esters increase GTP-dependent adenylate cyclase activity in rat brain striatal membranes.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Cholera Toxin; Colforsin; Corpus Striatum; Dopamine; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Male; Phorbol Esters; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Role of protein kinase C in the pigment cell of the lizard (Anolis carolinensis).
Topics: Animals; Colforsin; Drug Synergism; Lizards; Melanocyte-Stimulating Hormones; Melanocytes; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Specific regulation of vasoactive intestinal polypeptide biosynthesis by phorbol ester in bovine chromaffin cells.
Topics: Animals; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Enkephalin, Methionine; Enkephalins; Peptide Biosynthesis; Peptide PHI; Phorbols; Protein Precursors; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Vasoactive Intestinal Peptide | 1985 |
Differential effects of thyrotropin-releasing hormone, vasoactive intestinal peptide, phorbol ester, and depolarization in GH4C1 rat pituitary cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Colforsin; Diterpenes; Drug Synergism; Electrochemistry; Growth Hormone; Phorbols; Pituitary Gland; Potassium Chloride; Prolactin; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Time Factors; Vasoactive Intestinal Peptide | 1985 |
Inhibition of hCG-stimulated adenylate cyclase in purified mouse Leydig cells by the phorbol ester PMA.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cholera Toxin; Chorionic Gonadotropin; Colforsin; Diterpenes; Guanylyl Imidodiphosphate; Leydig Cells; Male; Mice; Phorbols; Testosterone; Tetradecanoylphorbol Acetate | 1985 |
Modulation of adenylate cyclase of human platelets by phorbol ester. Impairment of the hormone-sensitive inhibitory pathway.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alprostadil; Blood Platelets; Catalysis; Colforsin; Diterpenes; Enzyme Activation; Epinephrine; Guanosine Triphosphate; Humans; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate; Thrombin | 1985 |
Phorbol myristate acetate causes in guinea-pig lung parenchymal strip a maintained spasm which is relatively resistant to isoprenaline.
Topics: Aminophylline; Animals; Colforsin; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Lung; Male; Muscle Contraction; Muscle, Smooth; Nitroprusside; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Protein kinase C interferes with Ni-mediated inhibition of human platelet adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Blood Platelets; Cell Membrane; Chickens; Colforsin; Enzyme Activation; Epinephrine; Female; Guanosine Triphosphate; Humans; Oviducts; Protein Kinase C; Tetradecanoylphorbol Acetate | 1985 |
Role of protein kinase C in the synthesis of catecholamine by isolated bovine adrenal medullary cells.
Topics: Adrenal Medulla; Animals; Carbachol; Catecholamines; Cattle; Colforsin; In Vitro Techniques; Protein Kinase C; Tetradecanoylphorbol Acetate; Tyrosine | 1985 |
Effects of prostaglandin I2 and forskolin on the secretion from platelets evoked at basal concentrations of cytoplasmic free calcium by thrombin, collagen, phorbol ester and exogenous diacylglycerol.
Topics: Blood Platelets; Calcium; Colforsin; Collagen; Cyclic AMP; Cytoplasm; Diglycerides; Diterpenes; Epoprostenol; Humans; Tetradecanoylphorbol Acetate; Thrombin | 1984 |
Synergistic stimulation of prolactin release by phorbol ester, A23187 and forskolin.
Topics: Animals; Calcimycin; Calcium; Cell Line; Colforsin; Cyclic AMP; Diterpenes; Drug Synergism; Phorbols; Pituitary Neoplasms; Prolactin; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Time Factors | 1984 |
Effect of forskolin on prostaglandin synthesis by mouse resident peritoneal macrophages.
Topics: Animals; Ascitic Fluid; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; In Vitro Techniques; Macrophages; Male; Mice; Phagocytosis; Prostaglandins; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1984 |
Insulin secretion: combined tolbutamide, forskolin and TPA mimic action of glucose.
Topics: Animals; Colforsin; Diterpenes; Drug Interactions; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tolbutamide | 1984 |
TPA-induced contraction of isolated rabbit vascular smooth muscle.
Topics: Animals; Arteries; Calcimycin; Calcium; Colforsin; Diterpenes; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Phorbols; Phosphorylation; Protein Kinases; Rabbits; Tetradecanoylphorbol Acetate | 1984 |
Inhibition of denuded mouse oocyte meiotic maturation by tumor-promoting phorbol esters and its reversal by retinoids.
Topics: Animals; Colforsin; Diterpenes; Drug Interactions; Female; Meiosis; Mice; Oocytes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Retinoids; Tetradecanoylphorbol Acetate | 1984 |
Biosynthesis of large dense-core vesicles in PC12 cells: effects of depolarization and second messengers on the mRNA levels of their constituents.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Chromaffin Granules; Colforsin; Membrane Potentials; PC12 Cells; Rats; RNA, Messenger; Second Messenger Systems; Solubility; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1995 |
Cholecystokinin-stimulated enzyme secretion from dispersed rabbit pancreatic acinar cells: phosphorylation-dependent changes in potency and efficacy.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Amylases; Animals; Calcium-Transporting ATPases; Cells, Cultured; Cholecystokinin; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Pancreas; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Sincalide; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1995 |
Protein kinase C regulation of the adenylyl cyclase system in rat prostatic epithelium.
Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Guanylyl Imidodiphosphate; Isoproterenol; Male; Neuropeptides; Neurotransmitter Agents; Pertussis Toxin; Phosphorylation; Pituitary Adenylate Cyclase-Activating Polypeptide; Prostate; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide; Virulence Factors, Bordetella | 1995 |
Glucose stimulation of insulin release in the absence of extracellular Ca2+ and in the absence of any increase in intracellular Ca2+ in rat pancreatic islets.
Topics: Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Drug Interactions; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1995 |
PGE2 induces the transition from non-adherent to adherent bone marrow mesenchymal precursor cells via a cAMP/EP2-mediated mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bone Marrow; Bone Marrow Cells; Bucladesine; Cell Adhesion; Cells, Cultured; Colforsin; Colony-Forming Units Assay; Cyclic AMP; Dexamethasone; Dinoprostone; Female; Hematopoietic Stem Cells; Kinetics; Phosphodiesterase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Receptors, Prostaglandin E; Tetradecanoylphorbol Acetate | 1995 |
Inhibition of MAP kinase by prostaglandin E2 and forskolin in rat renal mesangial cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Glomerular Mesangium; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1995 |
Plasma membrane Na+/H+ exchanger isoforms (NHE-1, -2, and -3) are differentially responsive to second messenger agonists of the protein kinase A and C pathways.
Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Hydrogen-Ion Concentration; Protein Kinase C; Rats; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1995 |
Induction of apoptosis in cultured retinoblastoma cells by the protein phosphatase inhibitor, okadaic acid.
Topics: Apoptosis; Calcimycin; Cell Cycle; Cell Survival; Child, Preschool; Cholera Toxin; Colforsin; DNA, Neoplasm; Enzyme Inhibitors; Ethers, Cyclic; Etoposide; Flow Cytometry; HL-60 Cells; Humans; Male; Mitosis; Nocodazole; Okadaic Acid; Paclitaxel; Phosphoprotein Phosphatases; Retinoblastoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
Protein kinase regulation of tumor necrosis factor alpha stimulated collagenase and stromelysin message levels in chondrocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cartilage, Articular; Cell Membrane; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Enzyme Induction; Gene Expression Regulation; Isoquinolines; Kinetics; Matrix Metalloproteinase 3; Metalloendopeptidases; Neoplasm Proteins; Piperazines; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Swine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells.
Topics: Adolescent; Adult; Alprostadil; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Bryostatins; Calcimycin; Colforsin; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Lactones; Leukotriene C4; Lung; Macrolides; Mast Cells; Middle Aged; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandin D2; Skin; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Nerve growth factor stimulates GAP-43 expression in PC12 cell clones independently of neurite outgrowth.
Topics: Animals; Blotting, Western; Clone Cells; Colforsin; Cycloheximide; Dactinomycin; GAP-43 Protein; Membrane Glycoproteins; Nerve Growth Factors; Nerve Tissue Proteins; Neurites; PC12 Cells; RNA; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1993 |
Regulation of the ectopically expressed human glycoprotein alpha-subunit gene in the human hepatoma cell line NPLC.
Topics: Carcinoma, Hepatocellular; Cell Line; Colforsin; Dexamethasone; Gene Expression Regulation, Neoplastic; Glycoprotein Hormones, alpha Subunit; Humans; Hydroxyurea; Kinetics; Liver Neoplasms; Methotrexate; Protein Kinase C; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured | 1994 |
Expression of hepatocyte growth factor is up-regulated through activation of a cAMP-mediated pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Dexamethasone; Dinoprostone; Female; Fibroblasts; Gene Expression; Hepatocyte Growth Factor; Humans; Infant; Kinetics; Protein Kinase C; Recombinant Proteins; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1994 |
Induction of lactase biosynthesis in the human intestinal epithelial cell line Caco-2.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenocarcinoma; beta-Galactosidase; Bucladesine; Cell Line; Colforsin; Colonic Neoplasms; Cyclic AMP; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Epithelium; Humans; Lactase; Lactase-Phlorizin Hydrolase; Methionine; Microvilli; Sucrase-Isomaltase Complex; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Phorbol ester has different effects on forskolin and beta-adrenergic-stimulated cAMP accumulation in mouse parotid acini.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cytosol; In Vitro Techniques; Isoproterenol; Male; Membranes; Mice; Parotid Gland; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Cyclic AMP increases the release of parathyroid hormone-related protein from a lung-cancer cell line.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Bucladesine; Calcitonin; Carcinoma, Squamous Cell; Cell Line; Colforsin; Cyclic AMP; Humans; Kinetics; Lung Neoplasms; Neoplasm Proteins; Parathyroid Hormone-Related Protein; Protein Biosynthesis; Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Identification of a TPA-responsive element mediating preferential transactivation of the galanin gene promoter in chromaffin cells.
Topics: Adrenal Medulla; Animals; Base Sequence; Cattle; Cell Nucleus; Colforsin; Consensus Sequence; Cyclic AMP; DNA Primers; Endothelium, Vascular; Galanin; Gene Expression Regulation; Gene Library; HeLa Cells; Humans; Luciferases; Molecular Sequence Data; Mutagenesis, Site-Directed; Neuropeptides; Nuclear Proteins; Peptide Biosynthesis; Peptides; Promoter Regions, Genetic; RNA, Messenger; Second Messenger Systems; Sequence Deletion; Signal Transduction; TATA Box; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Phosphorylation of AMPA-type glutamate receptors by calcium/calmodulin-dependent protein kinase II and protein kinase C in cultured hippocampal neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glutamates; Glutamic Acid; Glycine; Hippocampus; Intracellular Signaling Peptides and Proteins; Ionomycin; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C; Proteins; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Tetradecanoylphorbol Acetate | 1994 |
Antiproliferative effect of prostaglandin E2 in cultured guinea pig tracheal smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blood Physiological Phenomena; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Guinea Pigs; Male; Muscle, Smooth; Tetradecanoylphorbol Acetate; Trachea | 1994 |
Regulation of human chorionic gonadotropin secretion and messenger ribonucleic acid levels by follistatin in the NUCC-3 choriocarcinoma cell line.
Topics: Calcimycin; Choriocarcinoma; Chorionic Gonadotropin; Chorionic Gonadotropin, beta Subunit, Human; Colforsin; Follistatin; Gene Expression Regulation; Glycoprotein Hormones, alpha Subunit; Glycoproteins; Gonadotropin-Releasing Hormone; Half-Life; Humans; Kinetics; Peptide Fragments; Placenta; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Pituitary adenylate cyclase-activating polypeptide effects in pituitary cells: modulation by gonadotropin-releasing hormone in alpha T3-1 cells.
Topics: 1-Methyl-3-isobutylxanthine; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Gonadotropin-Releasing Hormone; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
The role of protein kinase A and protein kinase C in prostanoid IP receptor desensitization in NG108-15 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Guanylyl Imidodiphosphate; Hybrid Cells; Iloprost; Isoquinolines; Mice; Piperazines; Protein Kinase C; Rats; Receptors, Prostaglandin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.
Topics: 3T3 Cells; Actins; Animals; Bombesin; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Genistein; GTP Phosphohydrolases; GTP-Binding Proteins; Isoflavones; Lysophospholipids; Mice; Models, Biological; Myosins; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Kinase C; Protein-Tyrosine Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1994 |
Multiple mitogenic signalling pathways in chromaffin cells: a model for cell cycle regulation in the nervous system.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Cell Cycle; Cell Division; Cells, Cultured; Colforsin; Dexamethasone; Ethers, Cyclic; Female; Models, Neurological; Nerve Endings; Nerve Growth Factors; Okadaic Acid; Phosphoprotein Phosphatases; Potassium Chloride; Rats; Rats, Inbred F344; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrodotoxin; Veratridine | 1994 |
Role of 3', 5' cyclic adenosine monophosphate and protein kinase C in the regulation of insulin-like growth factor-binding protein secretion by thyroid-stimulating hormone in isolated ovine thyroid cells.
Topics: Animals; Bucladesine; Carrier Proteins; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Insulin-Like Growth Factor Binding Proteins; Iodides; Protein Kinase C; Sheep; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1994 |
Involvement of a cAMP-responsive DNA element in mediating TRH responsiveness of the human thyrotropin alpha-subunit gene.
Topics: Animals; Base Sequence; Binding Sites; Calcium; Colforsin; Consensus Sequence; Cyclic AMP; DNA; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Genes; Glycoprotein Hormones, alpha Subunit; Humans; Molecular Sequence Data; Pituitary Neoplasms; Rats; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Sequence Deletion; Tetradecanoylphorbol Acetate; Thyrotropin; Thyrotropin-Releasing Hormone; Transcription Factor Pit-1; Transcription Factors; Tumor Cells, Cultured | 1994 |
PTP-PEST: a protein tyrosine phosphatase regulated by serine phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; Baculoviridae; Colforsin; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Peptide Mapping; Phorbol Esters; Phosphopeptides; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Protein Tyrosine Phosphatases; Recombinant Proteins; Sequence Analysis; Serine; Tetradecanoylphorbol Acetate | 1994 |
Role of protein kinase C in mediating NGF effect on neuropeptide Y expression in PC12 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Base Sequence; Binding Sites; Blotting, Northern; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Gene Expression; Isoquinolines; Kinetics; Molecular Sequence Data; Naphthalenes; Nerve Growth Factors; Neuropeptide Y; Oligodeoxyribonucleotides; PC12 Cells; Piperazines; Polycyclic Compounds; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Second messenger regulation of mouse gonadotropin-releasing hormone gene expression in immortalized mouse hypothalamic GT1-3 cells.
Topics: Animals; Cell Line, Transformed; Colforsin; Cyclic AMP; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Hypothalamus; Ionomycin; Mice; Mice, Transgenic; Protein Kinase C; RNA; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1994 |
Transcriptional regulation of plasminogen activator inhibitor-1 expression in human synovial fibroblasts by prostaglandin E2: mediation by protein kinase A and role of interleukin-1.
Topics: 1-Methyl-3-isobutylxanthine; Blood; Cadaver; Cells, Cultured; Colforsin; Culture Media; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1; Plasminogen Activator Inhibitor 1; Protein Kinase Inhibitors; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Inhibition of E-selectin gene transcription through a cAMP-dependent protein kinase pathway.
Topics: Base Sequence; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; E-Selectin; Endothelium, Vascular; Gene Expression Regulation; Humans; Intercellular Adhesion Molecule-1; Molecular Sequence Data; Nuclear Proteins; Oligodeoxyribonucleotides; Phosphorylation; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transcription, Genetic; Vascular Cell Adhesion Molecule-1 | 1994 |
Forskolin and PMA pretreatment of HT29 cells alters their chloride conductance induced by cAMP, Ca2+ and hypotonic cell swelling.
Topics: Adenosine Triphosphate; Blotting, Western; Calcium; Cell Line; Cell Size; Chloride Channels; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Hypotonic Solutions; Ionomycin; Membrane Proteins; Neurotensin; Tetradecanoylphorbol Acetate | 1994 |
Transfer of a constitutive viral promoter-cystic fibrosis transmembrane conductance regulator cDNA to human epithelial cells conveys resistance to down-regulation of cAMP-regulated Cl- secretion in the presence of inflammatory stimuli.
Topics: Blotting, Northern; Blotting, Southern; Chlorides; Colforsin; Colonic Neoplasms; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; DNA, Complementary; Epithelium; Gene Expression Regulation; Gene Transfer Techniques; Genetic Vectors; Membrane Proteins; Moloney murine leukemia virus; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Phorbol ester activation of protein kinase C inhibits CNP-stimulated cyclic GMP production in the mouse AtT-20 pituitary tumour cell line.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atrial Natriuretic Factor; Cell Line; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Kinetics; Mice; Natriuretic Peptide, C-Type; Pituitary Neoplasms; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1994 |
Pathways involved in muscarinic M1 and M2 receptor stimulation in rabbit vas deferens.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adenylyl Cyclase Inhibitors; Animals; Carbachol; Colforsin; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Lithium Chloride; Male; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Phosphatidylinositols; Rabbits; Receptors, Muscarinic; Signal Transduction; Stereoisomerism; Tetradecanoylphorbol Acetate; Vas Deferens | 1994 |
Vasoactive intestinal polypeptide stimulates cyclic AMP production in mouse N1E-115 neuroblastoma cells: modulation by a protein kinase C activator and ionomycin.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcium; Carcinogens; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Enzyme Activation; Ionomycin; Isoquinolines; Kinetics; Mice; Neuroblastoma; Phorbol Esters; Piperazines; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1994 |
Calcium efflux from cultured bovine adrenal chromaffin cells induced by pituitary adenylate cyclase-activating polypeptide (PACAP): possible involvement of an Na+/Ca2+ exchange mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Adrenal Medulla; Amiloride; Animals; Calcium; Carrier Proteins; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Inositol Phosphates; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate | 1995 |
Hormonal regulation of tissue-type plasminogen activator and plasminogen activator inhibitor type-1 in cultured monkey Sertoli cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Hormones; Macaca mulatta; Male; Plasminogen Activator Inhibitor 1; RNA Probes; RNA, Messenger; Sertoli Cells; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator | 1995 |
Calbindin expression in renal tubular epithelial cells. Altered sodium phosphate co-transport in association with cytoskeletal rearrangement.
Topics: Actins; Animals; Base Sequence; Biological Transport; Calbindins; Calcium; Cell Line; Colforsin; Cytoskeleton; Epithelial Cells; Epithelium; Fluorescent Antibody Technique; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Tubules; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Opossums; Phosphates; Phosphotyrosine; Proteins; Rats; Recombinant Proteins; S100 Calcium Binding Protein G; Sodium; Tetradecanoylphorbol Acetate; Tubulin; Tyrosine | 1995 |
Insulin-like growth factor binding protein production in human follicular thyroid carcinoma cells.
Topics: Adenocarcinoma, Follicular; Blotting, Northern; Carrier Proteins; Colforsin; Endopeptidases; Epidermal Growth Factor; Humans; Immunosorbent Techniques; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Thyrotropin; Tumor Cells, Cultured | 1995 |
Regulation of lysophosphatidic acid-stimulated tyrosine phosphorylation of pp42 mitogen-activated protein kinase by protein kinase C and protein kinase A in EAhy926 cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelium, Vascular; Indoles; Isoenzymes; Lysophospholipids; Phosphorylation; Phosphotyrosine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
Inhibition of serine/threonine protein phosphatases enhances agonist-stimulated cAMP accumulation in UMR 106 osteoblast-like cells.
Topics: 1-Methyl-3-isobutylxanthine; Antifungal Agents; Colforsin; Cyclic AMP; Dinoprostone; Ethers, Cyclic; Humans; Kinetics; Marine Toxins; Okadaic Acid; Osteoblasts; Oxazoles; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Protein Serine-Threonine Kinases; Proteins; Pyrans; Spiro Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Regulation of corticotropin-releasing factor secretion and synthesis in the human neuroblastoma clones- BE(2)-M17 and BE(2)-C.
Topics: Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Enzyme Activation; Humans; Interleukin-1; Neuroblastoma; Neuropeptides; Neurotransmitter Agents; Protein Kinase C; Serotonin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Expression of NOR-1 and its closely related members of the steroid/thyroid hormone receptor superfamily in human neuroblastoma cell lines.
Topics: Base Sequence; Cell Differentiation; Cell Line; Colforsin; Cycloheximide; DNA Primers; DNA-Binding Proteins; Gene Expression; Humans; Molecular Sequence Data; Nerve Tissue Proteins; Neuroblastoma; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Receptors, Thyroid Hormone; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1995 |
Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: a potential mechanism for inflammatory angiogenesis.
Topics: Arthritis, Rheumatoid; Bacterial Toxins; Base Sequence; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Endothelial Growth Factors; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1; Lymphokines; Molecular Sequence Data; Neovascularization, Pathologic; Prostaglandins E; Protein Kinase C; Receptors, Prostaglandin E; Signal Transduction; Synovial Fluid; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1995 |
Parathyroid hormone and parathyroid hormone-related peptide activate the Na+/H+ exchanger NHE-1 isoform in osteoblastic cells (UMR-106) via a cAMP-dependent pathway.
Topics: Animals; Bone Neoplasms; Cell Line; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Enzyme Inhibitors; Humans; Isoquinolines; Kinetics; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Protein Kinase C; Proteins; Rats; Recombinant Proteins; Second Messenger Systems; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1995 |
Dissociation between changes in cytoplasmic free Ca2+ concentration and insulin secretion as evidenced from measurements in mouse single pancreatic islets.
Topics: Animals; Biological Transport; Calcium; Cell Compartmentation; Colforsin; Cytoplasm; Enzyme Inhibitors; Ethers, Cyclic; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Membranes; Mice; Mice, Obese; Okadaic Acid; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1995 |
Complex intracellular signal transduction regulates tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type-1 (PAI-1) synthesis in cultured human umbilical vein endothelium.
Topics: Cells, Cultured; Colforsin; Endothelins; Endothelium, Vascular; Endotoxins; Ephedrine; Humans; Isoproterenol; Nitroprusside; Plasminogen Activator Inhibitor 1; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Tissue Plasminogen Activator; Umbilical Veins | 1995 |
Regulation of adrenocorticotropin secretion in vitro by anterior pituitary corticotrophs from fallow deer (Dama dama).
Topics: Adrenocorticotropic Hormone; Animals; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Deer; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Activation; Female; Glucocorticoids; Hormone Antagonists; Mifepristone; Pituitary Gland, Anterior; Protein Kinase C; Radioimmunoassay; Tetradecanoylphorbol Acetate; Vasopressins | 1995 |
Forskolin inhibits protein kinase C-induced mitogen activated protein kinase activity in MC3T3-E1 osteoblasts.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; DNA; Enzyme Activation; Enzyme Inhibitors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitogens; Osteoblasts; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Signal Transduction; Tetradecanoylphorbol Acetate | 1995 |
Intercellular heterogeneity of early mitogenic events: cAMP generalizes the EGF effect on c-Fos protein appearance but not on MAP kinase phosphorylation and nuclear translocation in dog thyroid epithelial cells.
Topics: Animals; Biological Transport; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Cycle; Cell Nucleus; Cells, Cultured; Colforsin; Cyclic AMP; Dogs; Epidermal Growth Factor; Epithelial Cells; Fluorescent Antibody Technique, Indirect; Hepatocyte Growth Factor; Mitogens; Phosphorylation; Proto-Oncogene Proteins c-fos; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1995 |
Insulin-like growth factor-II gene expression in a rat insulin-producing beta-cell line (INS-1) is regulated by glucose.
Topics: Animals; Cell Line; Colforsin; Dactinomycin; DNA; DNA Probes; Dose-Response Relationship, Drug; Gene Expression Regulation; Glucose; Insulin; Insulin-Like Growth Factor II; Islets of Langerhans; Luciferases; Rats; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymidine; Transfection | 1995 |
Cell-to-cell contact via measles virus haemagglutinin-CD46 interaction triggers CD46 downregulation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antibodies, Viral; Antigens, CD; Bucladesine; Cell Communication; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Hemagglutinins, Viral; Humans; Measles virus; Membrane Cofactor Protein; Membrane Glycoproteins; Mice; Phosphodiesterase Inhibitors; Protein Kinase C; Receptors, Virus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Ca2+ and cAMP activate different K+ conductances in the human intestinal goblet cell line HT29-Cl.16E.
Topics: Amphotericin B; Barium; Bumetanide; Calcimycin; Calcium; Carbachol; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Digitonin; Diphenylamine; Electric Conductivity; Epithelial Cells; Epithelium; Fura-2; Humans; Intestinal Mucosa; Membrane Potentials; Models, Biological; Ouabain; Potassium; Potassium Channels; Quinidine; Tetradecanoylphorbol Acetate; Thionucleotides; Vasoactive Intestinal Peptide | 1995 |
Enhancement of beta-galactosidase gene expression in rat pheochromocytoma cells by exposure to extremely low frequency magnetic fields.
Topics: Adrenal Gland Neoplasms; Animals; beta-Galactosidase; Colforsin; Dantrolene; Escherichia coli; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Magnetics; Naphthalenes; Nifedipine; PC12 Cells; Pheochromocytoma; Promoter Regions, Genetic; Protein Kinase C; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Vasoactive Intestinal Peptide | 1995 |
Interleukin-1 beta induction of tissue inhibitor of metalloproteinase (TIMP-1) is functionally antagonized by prostaglandin E2 in human synovial fibroblasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Northern; Bucladesine; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Dose-Response Relationship, Drug; Fibroblasts; Glycoproteins; Humans; Immunoenzyme Techniques; Interleukin-1; Isoquinolines; Metalloendopeptidases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Recombinant Proteins; RNA, Messenger; Staurosporine; Synovial Membrane; Tetradecanoylphorbol Acetate; Thionucleotides; Tissue Inhibitor of Metalloproteinases; Up-Regulation | 1995 |
Thapsigargin induces IL-2 receptor alpha-chain in human peripheral and Jurkat T cells via a protein kinase C-independent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Base Sequence; Calcimycin; Calcium; Calcium-Transporting ATPases; Cholera Toxin; Colforsin; Drug Synergism; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Humans; Hydroquinones; Isoquinolines; Leukemia-Lymphoma, Adult T-Cell; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Piperazines; Protein Kinase C; Receptors, Interleukin-2; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Staurosporine; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Regulation of heme oxygenase mRNA in mesangial cells: prostaglandin E2 negatively modulates interleukin-1-induced heme oxygenase-1 mRNA.
Topics: Animals; Base Sequence; Cells, Cultured; Colforsin; Dinoprostone; Gene Expression Regulation; Glomerular Mesangium; Heme Oxygenase (Decyclizing); Hot Temperature; Humans; Indomethacin; Interleukin-1; Kinetics; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate | 1995 |
Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase.
Topics: Amino Acid Sequence; Animals; Antigens; Arrestins; Base Sequence; beta-Adrenergic Receptor Kinases; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; Bucladesine; Cell Line; Colforsin; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; DNA Primers; Eye Proteins; Gene Expression; GTP-Binding Proteins; Molecular Sequence Data; Phosphorylation; Receptors, Adrenergic, beta-1; Tetradecanoylphorbol Acetate | 1995 |
Prostaglandin E2 regulation of ion transport is absent in medullary thick ascending limbs from SHR.
Topics: Absorption; Animals; Arginine Vasopressin; Bicarbonates; Biological Transport; Chlorides; Cholera Toxin; Colforsin; Dinoprostone; Hypertension; Ions; Kidney Medulla; Loop of Henle; Male; Osmolar Concentration; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate | 1995 |
Effect of glucagon on intracellular pH regulation in isolated rat hepatocyte couplets.
Topics: Animals; Antiporters; Bicarbonates; Bile; Bucladesine; Cells, Cultured; Chloride-Bicarbonate Antiporters; Chlorides; Cholagogues and Choleretics; Colchicine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glucagon; Hydrogen-Ion Concentration; Intracellular Fluid; Isoquinolines; Liver; Male; Nitrobenzoates; Rats; Rats, Wistar; Sodium; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Thionucleotides | 1995 |
Opposite regulation of renin gene expression by cyclic AMP and calcium in isolated mouse juxtaglomerular cells.
Topics: Animals; Autoradiography; Base Sequence; Calcium; Calcium Chloride; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Egtazic Acid; Gene Expression Regulation; Juxtaglomerular Apparatus; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Nitric Oxide; Polymerase Chain Reaction; Renin; RNA, Messenger; Tetradecanoylphorbol Acetate | 1995 |
In vitro effects of interactions of follicle-stimulating hormone, luteinizing hormone, and prolactin on progesterone synthesis by rat luteal cells during pregnancy.
Topics: Animals; Colforsin; Corpus Luteum; Cyclic AMP; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Luteinizing Hormone; Pregnancy; Pregnancy, Animal; Progesterone; Prolactin; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Species Specificity; Tetradecanoylphorbol Acetate | 1995 |
Modulation of intestinal chloride secretion at basolateral transport sites: opposing effects of cyclic adenosine monophosphate and phorbol ester.
Topics: Biological Transport; Bumetanide; Carrier Proteins; Cell Line; Chlorides; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Intestinal Mucosa; Rubidium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate | 1995 |
Regulation of the pituitary-specific transcription factor GHF-1/Pit-1 messenger ribonucleic acid levels by growth hormone-secretagogues in rat anterior pituitary cells in monolayer culture.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cycloheximide; Dactinomycin; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression; Growth Hormone; Growth Hormone-Releasing Hormone; Insulin-Like Growth Factor I; Male; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; RNA, Messenger; Somatostatin; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor Pit-1; Transcription Factors | 1995 |
Effects of vasoactive substances and cAMP related compounds on adrenomedullin production in cultured vascular smooth muscle cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenomedullin; Animals; Blood; Colforsin; Cyclic AMP; Endothelins; Epinephrine; Interferon-gamma; Muscle, Smooth, Vascular; Neuropeptides; Peptide Biosynthesis; Peptides; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thrombin; Transcription, Genetic; Vasoactive Intestinal Peptide | 1995 |
Parathyroid hormone and parathyroid hormone-related peptide inhibit the apical Na+/H+ exchanger NHE-3 isoform in renal cells (OK) via a dual signaling cascade involving protein kinase A and C.
Topics: Amino Acid Sequence; Animals; Cell Line; Colforsin; Cricetinae; Humans; Kidney; Molecular Sequence Data; Oligopeptides; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Protein Kinase C; Proteins; Rats; Signal Transduction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Substrate Specificity; Tetradecanoylphorbol Acetate | 1995 |
Activation of the basolateral Cl- conductance by cAMP in rabbit renal proximal tubule S3 segments.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bucladesine; Chloride Channels; Chlorides; Colforsin; Cyclic AMP; Diuretics; Female; Glycolates; In Vitro Techniques; Ion Transport; Ionomycin; Kidney Tubules, Proximal; Membrane Potentials; Parathyroid Hormone; Protein Kinase C; Rabbits; Sodium Chloride; Tetradecanoylphorbol Acetate; Thionucleotides; Uricosuric Agents | 1995 |
Patterns of expression of lineage-specific markers during the in vitro-induced differentiation of HT29 colon carcinoma cells.
Topics: Alkaline Phosphatase; Antigens, Differentiation; Antigens, Neoplasm; Biomarkers; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Carcinoma; Cell Differentiation; Colforsin; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Mucin-2; Mucin-3; Mucins; Neoplasm Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Intracellular mechanisms of cytoplasmic Ca2+ oscillation in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Alkaloids; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Cyclic AMP; Cytoplasm; Egtazic Acid; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Megakaryocytes; Models, Biological; Oscillometry; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1993 |
Protein kinase C regulation of prolactin gene expression in lactotroph cells: involvement in dopamine inhibition.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bromocriptine; Cells, Cultured; Colforsin; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Kinetics; Nifedipine; Pituitary Gland, Anterior; Potassium; Prolactin; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Receptor-activated calcium influx in human monocytes exposed to monocyte chemotactic protein-1 and related cytokines.
Topics: Calcium; Calcium Channels; Chemokine CCL2; Chemokine CCL4; Chemokine CCL5; Chemotactic Factors; Colforsin; Cytokines; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Lymphokines; Macrophage Inflammatory Proteins; Manganese; Monocytes; Monokines; Nifedipine; Recombinant Proteins; Tetradecanoylphorbol Acetate; Verapamil | 1993 |
Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-epsilon.
Topics: 1-Methyl-3-isobutylxanthine; Antibodies, Monoclonal; Antibody Specificity; Cells, Cultured; Colforsin; Diacylglycerol Kinase; Epidermal Growth Factor; Epitopes; ErbB Receptors; Escherichia coli; Humans; Peptide Mapping; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases; Phosphotyrosine; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1993 |
Phorbol ester stimulation of the type I and type III adenylyl cyclases in whole cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cell Line; Colforsin; Enzyme Activation; Gene Library; Humans; Isoenzymes; Kidney; Kinetics; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Bicarbonate induces sensitization of cyclic AMP accumulation by intact 1321N1 human astrocytoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Astrocytoma; Bicarbonates; Blood Physiological Phenomena; Colforsin; Cyclic AMP; Humans; Magnesium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Signal transduction pathways involved in T cell receptor-induced regulation of CD2 avidity for CD58.
Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Bucladesine; CD2 Antigens; CD58 Antigens; Colforsin; Cricetinae; Cyclic AMP; Humans; Membrane Glycoproteins; Mice; Protein Binding; Protein Kinase C; Protein-Tyrosine Kinases; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Antigen, T-Cell; Receptors, Immunologic; Rosette Formation; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 1993 |
Potentiation of NMDA receptor-mediated transmission in turtle cerebellar granule cells by activation of metabotropic glutamate receptors.
Topics: 2-Amino-5-phosphonovalerate; Adenylate Cyclase Toxin; Animals; Cerebellum; Colforsin; Cycloleucine; Evoked Potentials; In Vitro Techniques; Isomerism; Naphthalenes; Nitric Oxide; Pertussis Toxin; Polycyclic Compounds; Purkinje Cells; Quisqualic Acid; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Tetradecanoylphorbol Acetate; Turtles; Virulence Factors, Bordetella | 1993 |
Structural and functional changes of exocrine pancreas induced by FK506 in rats.
Topics: Amylases; Analysis of Variance; Animals; Atropine; Body Weight; Calcimycin; Calcium; Carbachol; Cholecystokinin; Colforsin; Cytosol; Dose-Response Relationship, Drug; Feeding Behavior; Kinetics; Male; N-Methylscopolamine; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Reference Values; Scopolamine; Scopolamine Derivatives; Secretin; Sincalide; Tacrolimus; Tetradecanoylphorbol Acetate; Time Factors; Trypsinogen; Vasoactive Intestinal Peptide | 1993 |
Evidence for the participation of protein kinase C and 3',5'-cyclic AMP-dependent protein kinase in the stimulation of muscle cell proliferation by 1,25-dihydroxy-vitamin D3.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Bucladesine; Calcitriol; Calcium; Calcium Channels; Cell Division; Cells, Cultured; Chick Embryo; Colforsin; Diglycerides; DNA; Dose-Response Relationship, Drug; Muscles; Nifedipine; Protein Kinase C; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Regulated expression of an intestinal mucin gene in HT29 colonic carcinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Bucladesine; Calcimycin; Colforsin; Colonic Neoplasms; DNA Probes; Ethers, Cyclic; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Ionomycin; Ionophores; Kinetics; Mucins; Okadaic Acid; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Regulation of two forms of the TNF receptors by phorbol ester and dibutyryl cyclic adenosine 3',5'-monophosphate in human histiocytic lymphoma cell line U-937.
Topics: 1-Methyl-3-isobutylxanthine; Bucladesine; Butyrates; Butyric Acid; Colforsin; Humans; Kinetics; Molecular Weight; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Interleukin-1-inducible expression of gro-beta via NF-kappa B activation is dependent upon tyrosine kinase signaling.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Cell Line; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Colforsin; Cytomegalovirus; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, jun; Genes, myc; Genistein; Growth Substances; HeLa Cells; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-1; Isoflavones; L Cells; Melanoma; Mice; Molecular Sequence Data; NF-kappa B; Oligonucleotide Probes; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1993 |
Lindane decreases forskolin-stimulated cyclic AMP accumulation but does not modify Gs in rat enterocytes.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Adenylyl Cyclases; Animals; Autoradiography; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hexachlorocyclohexane; Intestinal Mucosa; Jejunum; Kinetics; Male; Membrane Proteins; Phorbol Esters; Phosphorus Radioisotopes; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1993 |
Second messenger regulation of lipoprotein uptake by an arterial wall model.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Aorta; Calcimycin; Cattle; Cell Membrane Permeability; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Galanin; GTP-Binding Proteins; Lipid Bilayers; Lipoproteins; Lipoproteins, LDL; Muscle, Smooth, Vascular; Peptides; Pertussis Toxin; Protein Kinase C; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Neurohormonal regulation of histamine release from isolated rabbit fundic mucosal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Carbachol; Colforsin; Diglycerides; Dose-Response Relationship, Drug; Gastric Fundus; Gastric Mucosa; Gastrins; Histamine Release; Male; Muscarinic Antagonists; Prostaglandins; Rabbits; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate | 1993 |
Modulation of cell signaling pathways can enhance or impair glucocorticoid-induced gene expression without altering the state of receptor phosphorylation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Chloramphenicol O-Acetyltransferase; Colforsin; Dexamethasone; Ethers, Cyclic; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Luciferases; Mammary Tumor Virus, Mouse; Okadaic Acid; Phosphopeptides; Phosphorylation; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Receptors, Glucocorticoid; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1993 |
Prostaglandin E2 and other cyclic AMP elevating agents inhibit interleukin 2 gene transcription by counteracting calcineurin-dependent pathways.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcineurin; Calmodulin-Binding Proteins; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Dinoprostone; Gene Deletion; Gene Expression; Humans; Interleukin-2; Ionomycin; Kinetics; Mice; Phosphoprotein Phosphatases; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1993 |
Forskolin and phorbol myristate acetate inhibit intracellular Ca2+ mobilization induced by amitriptyline and bradykinin in rat frontocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Amitriptyline; Animals; Bradykinin; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Frontal Lobe; Imipramine; Inositol 1,4,5-Trisphosphate; Isoquinolines; Kinetics; Neurons; Piperazines; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate | 1993 |
Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Animals; Arachidonic Acid; Calcimycin; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diglycerides; Diterpenes; Dopamine D2 Receptor Antagonists; Ergolines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Protein Kinase C; Quinpirole; Raclopride; Receptors, Dopamine D2; Recombinant Proteins; Salicylamides; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Indirect inhibition by bradykinin of cyclic AMP generation in isolated rat glomeruli and mesangial cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Down-Regulation; Drug Interactions; Enzyme Activation; Glomerular Mesangium; Isoproterenol; Kidney Glomerulus; Male; Pertussis Toxin; Protein Kinase C; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Sodium fluoride stimulates exocytosis at a late site of calcium interaction in stimulus-secretion coupling: studies with the RINm5F beta cell line.
Topics: Aluminum; Animals; Arachidonic Acid; Calcium; Calcium-Binding Proteins; Cell Line; Colforsin; Cyclic AMP; Deferoxamine; Exocytosis; Extracellular Space; Insulin; Insulin Secretion; Ionomycin; Islets of Langerhans; Kinetics; Melitten; Nitrendipine; Potassium Chloride; Protein Kinase C; Secretory Rate; Sodium Fluoride; Stimulation, Chemical; Sulfonamides; Temperature; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1995 |
Differential regulation of primary response gene expression in skeletal muscle cells through multiple signal transduction pathways.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; DNA-Binding Proteins; Fibroblast Growth Factor 2; Gene Expression Regulation; Mice; Muscles; Nuclear Receptor Subfamily 4, Group A, Member 1; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 1995 |
Protein kinase A induces phosphorylation of the human 5-HT1A receptor and augments its desensitization by protein kinase C in CHO-K1 cells.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Heparin; Humans; Kinetics; Phosphorylation; Protein Kinase C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Sphingosine; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection | 1994 |
G-protein regulation of capacitative calcium entry may be mediated by protein kinases A and C in Xenopus oocytes.
Topics: Adenylyl Cyclases; Aluminum Compounds; Animals; Calcium; Chloride Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Enzyme Activation; Female; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Oocytes; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases; Xenopus laevis | 1995 |
Interactions between second messenger pathways influence NGF synthesis in mouse primary astrocytes.
Topics: Animals; Astrocytes; Blood Physiological Phenomena; Calcimycin; Cells, Cultured; Colforsin; Mice; Mice, Inbred Strains; Nerve Growth Factors; Proto-Oncogene Proteins; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1995 |
Vasoactive intestinal peptide gene expression in the rat pheochromocytoma cell line PC12.
Topics: Animals; Base Sequence; Cloning, Molecular; Colforsin; DNA Primers; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; Molecular Sequence Data; Neurons; PC12 Cells; Promoter Regions, Genetic; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Vasoactive Intestinal Peptide | 1995 |
Autoregulation of inducible prostaglandin G/H synthase in osteoblastic cells by prostaglandins.
Topics: 3T3 Cells; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Blotting, Western; Cells, Cultured; Colforsin; Dinoprost; Dinoprostone; DNA, Complementary; Enzyme Induction; Mice; Nucleic Acid Hybridization; Osteoblasts; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1995 |
Regulation of follistatin messenger ribonucleic acid in steroidogenic rat granulosa cell lines.
Topics: Animals; Cell Line; Cell Line, Transformed; Chorionic Gonadotropin; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA, Viral; Female; Follicle Stimulating Hormone; Follistatin; Gene Expression Regulation; Genes, ras; Glycoproteins; Granulosa Cells; Kinetics; Protein Kinase C; Rats; RNA, Messenger; Simian virus 40; Steroids; Tetradecanoylphorbol Acetate; Transfection | 1995 |
Differential regulation of sympathetic neuron neuropeptide Y and catecholamine content and secretion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Bucladesine; Calcimycin; Catecholamines; Cells, Cultured; Colforsin; Dopamine; Electrochemistry; Female; Homeostasis; Homovanillic Acid; Immunohistochemistry; Kinetics; Neurons; Neuropeptide Y; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Multiple intracellular signallings are involved in thyrotropin-releasing hormone (TRH)-induced c-fos and jun B mRNA levels in clonal prolactin cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Clone Cells; Colforsin; Cyclic AMP; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Ionomycin; Neoplasm Proteins; Nuclear Proteins; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1995 |
Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in FRTL-5 cells. II. Down-regulation by v-K-ras oncogene.
Topics: Acetates; Activating Transcription Factor 2; Animals; Antibodies; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Gene Expression Regulation, Enzymologic; Genes, ras; Hydroxymethylglutaryl CoA Reductases; Kinetics; Kirsten murine sarcoma virus; Leucine Zippers; Moloney murine sarcoma virus; Mutagenesis; Protein Kinase C; Rats; RNA, Messenger; Temperature; Tetradecanoylphorbol Acetate; Thyroid Gland; Transcription Factors | 1995 |
Luteotropic effects of follicle-stimulating hormone (FSH): II. FSH luteinizing hormone, and prolactin effects on second messenger systems in the corpus luteum of the pregnant hamster.
Topics: Animals; Bucladesine; Colforsin; Corpus Luteum; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Pregnancy; Progesterone; Prolactin; Protein Kinase C; Recombinant Proteins; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1994 |
Distinct mechanisms for Ca2+ entry induced by OKT3 and Ca2+ depletion in Jurkat T cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Calcium; Calcium Channel Blockers; Cations, Divalent; Cholera Toxin; Colforsin; Humans; Inositol Phosphates; Ion Channel Gating; Ion Transport; Lymphocyte Activation; Muromonab-CD3; Pertussis Toxin; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1995 |
Melatonin regulates the phosphorylation of CREB in ovine pars tuberalis.
Topics: Animals; Base Sequence; Cell Nucleus; Cells, Cultured; Colforsin; Consensus Sequence; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Melatonin; Molecular Sequence Data; Phosphorylation; Pituitary Gland, Anterior; Protein Kinase C; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
The site of action of Ca2+ in the activation of steroidogenesis: studies in Ca(2+)-clamped bovine adrenal zona-glomerulosa cells.
Topics: Aldosterone; Angiotensin II; Animals; Bucladesine; Calcium; Cattle; Cholesterol; Colforsin; Cyclic AMP; Cycloheximide; Dose-Response Relationship, Drug; Hydroxycholesterols; Ionomycin; Pregnanolone; Tetradecanoylphorbol Acetate; Zona Glomerulosa | 1995 |
Regulation of tyrosine hydroxylase in olfactory bulb cultures: selective inhibition of depolarization-induced increase by endogenous opioids.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dexamethasone; Enzyme Activation; Membrane Potentials; Neurons; Olfactory Bulb; Opioid Peptides; Potassium Chloride; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1994 |
Mutual antagonistic interactions between the thyrotropin (adenosine 3',5'-monophosphate) and protein kinase C/epidermal growth factor (tyrosine kinase) pathways in cell proliferation and differentiation of cultured human thyroid follicles.
Topics: Alkaloids; Cell Differentiation; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Epidermal Growth Factor; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein-Tyrosine Kinases; Second Messenger Systems; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1995 |
TGF-beta 1 and cyclic AMP promote apoptosis in resting human B lymphocytes.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Apoptosis; B-Lymphocytes; Cells, Cultured; Colforsin; Cyclic AMP; DNA Damage; Humans; Lectins, C-Type; Lymphocyte Activation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thionucleotides; Transforming Growth Factor beta | 1995 |
Tumor-promoting phorbol ester-induced cell death and gene expression in a human prostate adenocarcinoma cell line.
Topics: Adenocarcinoma; Androgens; Base Sequence; Cell Death; Cell Division; Colforsin; Gene Expression; Gene Expression Regulation, Neoplastic; Genes, Immediate-Early; Humans; Male; Molecular Sequence Data; Prostatic Neoplasms; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured | 1994 |
Vitamin D hydroxylases and their regulation in a naturally vitamin D-deficient subterranean mammal, the naked mole rat (Heterocephalus glaber).
Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Bucladesine; Cholestanetriol 26-Monooxygenase; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Diglycerides; Female; Humans; Kidney; Liver; Male; Protein Kinase C; Rodentia; Signal Transduction; Steroid Hydroxylases; Tetradecanoylphorbol Acetate; Vitamin D Deficiency; Vitamin D3 24-Hydroxylase | 1993 |
Transcriptional vs. posttranscriptional control of neuropeptide Y gene expression.
Topics: Animals; Colforsin; Dichlororibofuranosylbenzimidazole; Drug Stability; Gene Expression Regulation; Neuroblastoma; Neuropeptide Y; PC12 Cells; Promoter Regions, Genetic; Protein Processing, Post-Translational; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1995 |
Comparative regulation of inhibin, activin and human chorionic gonadotropin production by placental trophoblast cells in culture.
Topics: Activins; Blotting, Western; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Culture Media, Conditioned; Cyclic AMP; Dexamethasone; Enzyme Activation; Epinephrine; Female; Gonadotropin-Releasing Hormone; Humans; Inhibins; Pregnancy; Protein Kinase C; Tetradecanoylphorbol Acetate; Trophoblasts | 1994 |
Dopaminergic regulation of transcription factor expression in organotypic cultures of developing striatum.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Colforsin; Corpus Striatum; Cyclic AMP; Cycloheximide; Dopamine; Dopamine Agonists; Dopamine Antagonists; Gene Expression Regulation; Molecular Sequence Data; Nerve Tissue Proteins; Organ Culture Techniques; Protein Kinase C; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1995 |
Synaptotagmin IV is an immediate early gene induced by depolarization in PC12 cells and in brain.
Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Base Sequence; Brain; Calcium-Binding Proteins; Cell Line; Colforsin; DNA Primers; Gene Expression; Gene Library; Genes, Immediate-Early; Hippocampus; Kainic Acid; Male; Membrane Glycoproteins; Membrane Potentials; Mice; Molecular Sequence Data; Nerve Tissue Proteins; Oligonucleotide Probes; Organ Specificity; PC12 Cells; Pheochromocytoma; Polymerase Chain Reaction; Potassium; Rats; Rats, Sprague-Dawley; RNA, Messenger; Seizures; Sequence Homology, Amino Acid; Synaptotagmins; Tetradecanoylphorbol Acetate | 1995 |
Effects of second messengers on the permeability and morphology of eel rete capillaries.
Topics: Albumins; Animals; Bucladesine; Calcimycin; Calcium; Capillaries; Capillary Permeability; Colforsin; Diglycerides; Eels; Isoproterenol; Microscopy, Electron; Nucleotides, Cyclic; Phosphatidylinositols; Second Messenger Systems; Sodium; Sucrose; Tetradecanoylphorbol Acetate | 1995 |
Down-regulation of the gonadotropin-releasing hormone receptor messenger ribonucleic acid by activation of adenylyl cyclase in alpha T3-1 pituitary gonadotrope cells.
Topics: Adenylyl Cyclases; Animals; Blotting, Northern; Cell Line; Colforsin; Down-Regulation; Enzyme Activation; Gene Expression Regulation; Gonadotropin-Releasing Hormone; Mice; Pituitary Gland; RNA, Messenger; Tetradecanoylphorbol Acetate | 1995 |
Heterologous sensitization of adenylate cyclase activity by serotonin in the rat cerebral cortex.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Colforsin; Guanylyl Imidodiphosphate; In Vitro Techniques; Isoproterenol; Male; Phorbol 12,13-Dibutyrate; Propanolamines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Somatostatin; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1993 |
The activation of protein kinase C prevents PGE2-induced inhibition of AVP-dependent cAMP accumulation in the rat outer medullary collecting tubule.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Animals; Arginine Vasopressin; Clonidine; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Activation; Kidney Medulla; Kidney Tubules, Collecting; Male; Osmolar Concentration; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Different sensitivity of alpha 2A-C10 and alpha 2C-C4 receptor subtypes in coupling to inhibition of cAMP accumulation.
Topics: Adenine; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Clonidine; Colforsin; Cyclic AMP; Fibroblasts; Humans; Imidazoles; Kinetics; Medetomidine; Norepinephrine; Receptors, Adrenergic, alpha-2; Tetradecanoylphorbol Acetate; Transfection; Yohimbine | 1994 |
Chief cells possess somatostatin receptors regulated by secretagogues acting through the calcium or cAMP pathway.
Topics: Animals; Binding, Competitive; Calcium; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Epithelial Cells; Epithelium; Gastric Mucosa; Guinea Pigs; Kinetics; Male; Octreotide; Receptors, Somatostatin; Second Messenger Systems; Secretin; Somatostatin; Tetradecanoylphorbol Acetate; Thermodynamics; Vasoactive Intestinal Peptide | 1994 |
Cyclic AMP-dependent protein kinase regulates basal and cyclic AMP-stimulated but not phorbol ester-stimulated transcription of the tyrosine hydroxylase gene.
Topics: Base Sequence; Carrier Proteins; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Gene Expression Regulation; Humans; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Neuroblastoma; Protein Kinase C; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1994 |
Cross-talk modulation of signal transduction pathways: two mechanisms are involved in the control of tyrosine aminotransferase gene expression by phorbol esters.
Topics: Animals; Base Sequence; Cell Line; Chromatin; Colforsin; Corticosterone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Enhancer Elements, Genetic; Enzyme Induction; Genes; Liver; Liver Neoplasms, Experimental; Molecular Sequence Data; Protein Binding; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Receptors, Steroid; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tyrosine Transaminase | 1994 |
Functional behavior of the beta-adrenergic receptor-adenylyl cyclase system in rabbit airway epithelium.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Betaxolol; Binding, Competitive; Bradykinin; Colforsin; Cyclic AMP; Dinoprostone; Epithelial Cells; Epithelium; Glycerol; Isoproterenol; Kinetics; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate; Trachea | 1994 |
Homology cloning of rat 72 kDa type IV collagenase: cytokine and second-messenger inducibility in glomerular mesangial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; Cloning, Molecular; Colforsin; Collagenases; Cytokines; DNA; Glomerular Mesangium; Interleukin-1; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Recombinant Proteins; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Synergistic effects between protein kinase C and cAMP on activator protein-1 activity and differentiation of PC-12 pheochromocytoma cells.
Topics: Animals; Cell Differentiation; Colforsin; Cyclic AMP; Drug Synergism; Neoplasm Proteins; Neurites; PC12 Cells; Pheochromocytoma; Protein Binding; Protein Kinase C; Rats; Regulatory Sequences, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 1993 |
Stimulation of androgen-regulated transactivation by modulators of protein phosphorylation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androgen Antagonists; Androgens; Anilides; Animals; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA; Enzyme Activation; Ethers, Cyclic; HeLa Cells; Humans; Molecular Sequence Data; Nitriles; Okadaic Acid; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Receptors, Androgen; Testosterone; Tetradecanoylphorbol Acetate; Tosyl Compounds; Transcriptional Activation | 1994 |
Jun B expression is regulated differently by three mitogenic pathways in thyrocytes.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dogs; Epidermal Growth Factor; Gene Expression Regulation; In Vitro Techniques; Mitosis; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Transcription, Genetic | 1994 |
Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells.
Topics: Adrenal Medulla; Animals; Base Sequence; Cattle; Cell Nucleus; Cells, Cultured; Colforsin; Cyclic AMP; Cytoplasm; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Models, Biological; Molecular Sequence Data; Promoter Regions, Genetic; Protein Kinase C; Receptors, Angiotensin; Receptors, Cholinergic; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1994 |
Modulation of adenylylcyclase by protein kinase C in human neurotumor SK-N-MC cells: evidence that the alpha isozyme mediates both potentiation and desensitization.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Alkaloids; Aluminum Compounds; Animals; Brain; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Dopamine; Drug Synergism; Fluorides; GTP-Binding Proteins; Humans; Isoenzymes; Isoproterenol; Kinetics; Manganese; Neuroblastoma; Neuropeptide Y; Propanolamines; Protein Kinase C; Rats; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Role for glial cells in regulating the functional expression of neuropeptide Y (NPY) neurons in aggregate cultures derived from dissociated fetal brain cells.
Topics: Animals; Brain; Cells, Cultured; Colforsin; Culture Media, Conditioned; Cytarabine; DNA; Immunohistochemistry; Kinetics; Male; Neuroglia; Neurons; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thymidine | 1994 |
Insulin secretion by the pancreatic beta cell of aged rats.
Topics: Aging; Animals; Colforsin; Dose-Response Relationship, Drug; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nifedipine; Potassium; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1994 |
Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Alkaloids; Animals; Bucladesine; Calcimycin; Calmodulin; Cell Line; Colforsin; Culture Media; Cytoplasm; Dyneins; Edetic Acid; Ethers, Cyclic; Imidazoles; Kidney; Kinetics; Macromolecular Substances; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate | 1994 |
Cell type- and region-specific expression of aromatase mRNA in cultured brain cells.
Topics: Animals; Aromatase; Astrocytes; Brain; Cells, Cultured; Cerebral Cortex; Colforsin; Dexamethasone; Diencephalon; Embryo, Mammalian; Estradiol; Female; Gene Expression; Kinetics; Mice; Mice, Inbred ICR; Neurons; Polymerase Chain Reaction; Pregnancy; RNA, Messenger; Testosterone; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Phosphorylation and expression of connexin-43 ovarian gap junction protein are regulated by luteinizing hormone.
Topics: Alkaloids; Animals; Blotting, Northern; Blotting, Western; Cells, Cultured; Colforsin; Connexin 43; Electrophoresis, Polyacrylamide Gel; Female; Gap Junctions; Gene Expression; Granulosa Cells; Kinetics; Luteinizing Hormone; Meiosis; Ovarian Follicle; Ovary; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Role of myosin light-chain kinase and protein kinase C in pepsinogen secretion from guinea pig gastric chief cells in monolayer culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Calcium; Carbachol; Cells, Cultured; Colforsin; Gastric Mucosa; Guinea Pigs; Immunoenzyme Techniques; Ionomycin; Isoquinolines; Male; Microscopy, Electron; Myosin-Light-Chain Kinase; Pepsinogens; Piperazines; Protein Kinase C; Rabbits; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1994 |
Determination of the promoter elements that mediate repression of c-fos gene transcription by thyroid hormone and retinoic acid receptors.
Topics: Base Sequence; Cells, Cultured; Colforsin; Genes, fos; Molecular Sequence Data; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Intracellular mediators of goblet cell degranulation in isolated pancreatic ducts.
Topics: Animals; Calcimycin; Carbachol; Cell Degranulation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytochalasin D; Dichlororibofuranosylbenzimidazole; Enzyme Activation; Ethers, Cyclic; Guinea Pigs; In Vitro Techniques; Male; Nocodazole; Okadaic Acid; Pancreatic Ducts; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides; Vasoactive Intestinal Peptide | 1994 |
Involvement of high-affinity binding site for EGF receptor in formation of rounding in A-431 epidermoid carcinoma cells.
Topics: Binding Sites; Carcinoma, Squamous Cell; Colforsin; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Kanamycin Kinase; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1994 |
Biosynthesis of proteins of large dense-core vesicles in rat PC12 cells: regulation by forskolin and phorbol ester.
Topics: Animals; Blotting, Northern; Chromogranins; Colforsin; Dopamine beta-Hydroxylase; Kinetics; Membrane Proteins; Neuropeptide Y; PC12 Cells; Rats; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Protein kinase-dependent Cl- currents in feline ventricular myocytes.
Topics: Animals; Cats; Chloride Channels; Chlorides; Colforsin; Electrophysiology; Isoproterenol; Myocardium; Osmolar Concentration; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Ventricular Function | 1994 |
In vivo phosphorylation of the Na,K-ATPase alpha subunit in sciatic nerves of control and diabetic rats: effects of protein kinase modulators.
Topics: Alkaloids; Animals; Blotting, Western; Calcium; Colforsin; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Isoenzymes; Kinetics; Macromolecular Substances; Male; Membrane Proteins; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Reference Values; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
The effects of growth factors and phorbol esters on steroid biosynthesis in isolated human theca interna and granulosa-lutein cells in long term culture.
Topics: Aromatase; Bucladesine; Cells, Cultured; Colforsin; Dehydroepiandrosterone; Epidermal Growth Factor; Female; Fibroblast Growth Factors; Granulosa Cells; Growth Substances; Humans; Insulin; Insulin-Like Growth Factor I; Luteal Cells; Progesterone; Steroid 17-alpha-Hydroxylase; Steroids; Tetradecanoylphorbol Acetate; Theca Cells; Transforming Growth Factor beta | 1994 |
Differential requirements for p21ras and protein kinase C in the regulation of neuronal gene expression by nerve growth factor and neurokines.
Topics: Choline O-Acetyltransferase; Ciliary Neurotrophic Factor; Colforsin; Gene Expression Regulation; Genes, fos; Growth Inhibitors; Humans; In Vitro Techniques; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Nerve Growth Factors; Nerve Tissue Proteins; Neurons; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate; Transcriptional Activation; Vasoactive Intestinal Peptide | 1994 |
Basal and induced amounts of interleukin-6 mRNA decline progressively with age in human fibroblasts.
Topics: Blood; Cell Division; Cell Nucleus; Cells, Cultured; Cellular Senescence; Colforsin; Cycloheximide; Diploidy; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-6; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
A c-fos/c-jun-like factor and the pituitary-specific factor Pit-1 are both necessary to mediate induction of the human thyrotropin beta promoter.
Topics: Base Sequence; Cell Line; Colforsin; DNA; DNA-Binding Proteins; Gene Expression Regulation; HeLa Cells; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Thyrotropin; Thyrotropin-Releasing Hormone; Transcription Factor Pit-1; Transcription Factors | 1993 |
Multi-site phosphorylation of the inhibitory guanine nucleotide regulatory protein Gi-2 occurs in intact rat hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Binding Sites; Colforsin; Glucagon; GTP-Binding Proteins; Immunosorbent Techniques; Isoelectric Point; Liver; Male; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Phosphoserine; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Trypsin; Vasopressins | 1994 |
In vivo phosphorylation of 2',3'-cyclic nucleotide 3'-phosphohydrolase (CNP): CNP in brain myelin is phosphorylated by forskolin- and phorbol ester-sensitive protein kinases.
Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Animals; Brain; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Myelin Sheath; Phorbol Esters; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Protein Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1994 |
Modulation of nucleocytosolic [Ca2+] gradient in smooth muscle by protein phosphorylation.
Topics: Adenosine Triphosphate; Animals; Benzoquinones; Calcium; Cell Line; Cell Nucleus; Colforsin; Cricetinae; Cytosol; Diacylglycerol Kinase; Epidermal Growth Factor; Ethers, Cyclic; Homeostasis; Kinetics; Lactams, Macrocyclic; Leiomyosarcoma; Marine Toxins; Mesocricetus; Models, Biological; Muscle, Smooth; Okadaic Acid; Oxazoles; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Protein Kinase C; Protein Kinases; Protein Tyrosine Phosphatases; Quinazolines; Quinazolinones; Quinones; Rifabutin; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1994 |
Signal transduction pathways of bacterial lipopolysaccharide-stimulated bovine vascular endothelial cells.
Topics: Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Colforsin; Endothelium, Vascular; Enzyme Activation; Lipopolysaccharides; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboplastin | 1994 |
Cortisol inhibition of growth hormone-releasing hormone-stimulated growth hormone release from cultured sheep pituitary cells.
Topics: Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cells, Cultured; Colforsin; Depression, Chemical; Growth Hormone; Growth Hormone-Releasing Hormone; Hydrocortisone; Male; Pertussis Toxin; Pituitary Gland; Potassium Chloride; Puromycin; Sheep; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1994 |
Differential regulation of natriuretic peptide receptor activity in vascular cells.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Muscle, Smooth, Vascular; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
Basal and inducible transcriptional activity of an upstream AP-1/CRE element (DYNCRE3) in the prodynorphin promoter.
Topics: Animals; Base Sequence; Colforsin; Cyclic AMP; Enkephalins; Gene Expression Regulation; HeLa Cells; Humans; Molecular Sequence Data; PC12 Cells; Plasmids; Promoter Regions, Genetic; Protein Precursors; Rats; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 1994 |
Agonist-induced phosphorylation of the vascular type 1 angiotensin II receptor.
Topics: Angiotensin II; Animals; Autoradiography; Cells, Cultured; Colforsin; Immunoblotting; Ionomycin; Male; Muscle, Smooth, Vascular; Phosphorylation; Precipitin Tests; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Serine; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Developmental appearance of pineal adrenergic-->guanosine 3',5'-monophosphate response is determined by a process down-stream from elevation of intracellular Ca2+: possible involvement of a diffusible factor.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adrenal Glands; Aging; Animals; Arachidonic Acid; Calcium; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Cytosol; Guanylate Cyclase; Isoproterenol; Kinetics; Mice; Norepinephrine; Organ Culture Techniques; Phospholipases A; Phospholipases A2; Pineal Gland; Potassium; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1993 |
Mechanisms of action of a second generation growth hormone-releasing peptide (Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2) in rat anterior pituitary cells.
Topics: Amino Acid Sequence; Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; Kinetics; Male; Molecular Sequence Data; Nifedipine; Oligopeptides; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Somatostatin; Tetradecanoylphorbol Acetate | 1993 |
Phorbol ester (PMA)-induced biphasic contraction of the rat aorta and effects of sodium nitroprusside and forskolin on the contraction.
Topics: Adenylyl Cyclases; Animals; Aorta, Thoracic; Calcium; Calcium Channels; Colforsin; Drug Interactions; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Neurotoxic effect of okadaic acid, a seafood-related toxin, on cultured cerebellar neurons.
Topics: Animals; Cell Death; Cells, Cultured; Cerebellum; Colforsin; Ethers, Cyclic; Glutamates; Glutamic Acid; Kainic Acid; Marine Toxins; Models, Neurological; Neurons; Neurotoxins; Okadaic Acid; Phosphoprotein Phosphatases; Rats; Shellfish; Tetradecanoylphorbol Acetate | 1993 |
Basic fibroblast growth factor selectively amplifies the functional state of neurons producing neuropeptide Y but not somatostatin in cultures of fetal brain cells: evidence for a cooperative interaction with insulin-like growth factor-I.
Topics: Animals; Brain; Cells, Cultured; Colforsin; Drug Synergism; Fetus; Fibroblast Growth Factor 2; Insulin-Like Growth Factor I; Neurons; Neuropeptide Y; Somatostatin; Tetradecanoylphorbol Acetate | 1993 |
Expression of follistatin messenger ribonucleic acid in Sertoli cell-enriched cultures: regulation by epidermal growth factor and protein kinase C-dependent pathway but not by follicle-stimulating hormone and protein kinase A-dependent pathway.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Fetal Blood; Follicle Stimulating Hormone; Follistatin; Glycoproteins; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sertoli Cells; Tetradecanoylphorbol Acetate | 1993 |
Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles.
Topics: Base Sequence; Binding Sites; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; DNA-Binding Proteins; Gene Expression; Interleukin-2; Kinetics; NF-kappa B; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1994 |
Induction of FOS and JUN proteins by adrenocorticotropin and phorbol ester but not by 3',5'-cyclic adenosine monophosphate derivatives.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Alkaloids; Animals; Bucladesine; Colforsin; Cycloheximide; Dactinomycin; Enzyme Induction; Genes, fos; Genes, jun; Kinetics; Mice; Neoplasm Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
A common response element mediates differential effects of phorbol esters and forskolin on type-1 plasminogen activator inhibitor gene expression in human breast carcinoma cells.
Topics: Base Sequence; Binding Sites; Breast Neoplasms; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Proto-Oncogene Proteins c-jun; Signal Transduction; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Agonist-induced desensitization and loss of high-affinity binding sites of stably expressed human 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors; Arachidonic Acid; Binding Sites; Calcium; Colforsin; Enzyme Activation; HeLa Cells; Humans; Ligands; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Quinacrine; Receptors, Serotonin; Serotonin; Tetradecanoylphorbol Acetate | 1994 |
Steroidogenic enzyme activity after acute activation of protein kinase (PK) A and PKC in ovine small and large luteal cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Adenylyl Cyclases; Animals; Cell Size; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Corpus Luteum; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Lipoproteins, HDL; Luteinizing Hormone; Progesterone; Protein Kinase C; Sheep; Sterol Esterase; Tetradecanoylphorbol Acetate | 1993 |
Mode of action of prostaglandin F2 alpha in human luteinized granulosa cells: role of protein kinase C.
Topics: Bucladesine; Calcium; Cells, Cultured; Cholera Toxin; Cloprostenol; Colforsin; Cyclic AMP; Dinoprost; Female; Granulosa Cells; Humans; Hydroxycholesterols; Luteinizing Hormone; Pregnenolone; Progesterone; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
Protein kinase C is crucial for the stimulation of sodium-dependent phosphate transport by parathyroid hormone-related peptide in osteoblast-like cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Biological Transport; Bone Neoplasms; Calcimycin; Calcium; Cell Line; Colforsin; Cytosol; Humans; Isoquinolines; Kinetics; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Phosphates; Piperazines; Protein Kinase C; Proteins; Rats; Sodium; Tetradecanoylphorbol Acetate | 1994 |
Stimulation of glucagon-like peptide-1 secretion by muscarinic agonist in a murine intestinal endocrine cell line.
Topics: Calcium; Carbachol; Cell Line; Colforsin; Cyclic AMP; Endocrine Glands; Glucagon; Glucagon-Like Peptide 1; Intestinal Mucosa; Intestines; Kinetics; Muscarinic Antagonists; N-Methylscopolamine; Parasympathomimetics; Peptide Fragments; Protein Precursors; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate | 1994 |
Cellular distribution and regulation by cAMP of the GABA transporter (GAT-1) mRNA.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Astrocytes; Base Sequence; Bucladesine; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Cloning, Molecular; Colforsin; Cyclic AMP; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Immunohistochemistry; Kinetics; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Neuroglia; Oligodeoxyribonucleotides; Organic Anion Transporters; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Interactions between TGF-beta and adrenocorticotropin in growth regulation of human adrenal fetal zone cells.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Bucladesine; Cell Division; Cells, Cultured; Colforsin; Cosyntropin; DNA; Drug Interactions; Fetus; Humans; Tetradecanoylphorbol Acetate; Thymidine; Transforming Growth Factor beta | 1994 |
Neuropeptide Y enhances LHRH binding to rat gonadotrophs in primary culture.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calmodulin; Cells, Cultured; Colforsin; Cyclic AMP; Gonadotropin-Releasing Hormone; GTP-Binding Proteins; Isoquinolines; Male; Neuropeptide Y; Pertussis Toxin; Piperazines; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1994 |
Inhibition of procoagulant activity of human monocytes by chenodeoxycholic acid: involvement of protein kinase C.
Topics: Alkaloids; Blood Coagulation; Bucladesine; Chenodeoxycholic Acid; Colforsin; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Humans; Monocytes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Modulation of cyclic AMP metabolism by protein kinase C in PC18 cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Colforsin; Cyclic AMP; Humans; Phenylisopropyladenosine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Effects of CGRP, forskolin, PMA, and ionomycin on pHi dependence of Na-H exchange in UMR-106 cells.
Topics: Animals; Calcitonin Gene-Related Peptide; Colforsin; Hydrogen-Ion Concentration; Intracellular Membranes; Ionomycin; Osteoblasts; Rats; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Biphasic regulation by N6,2'-O-dibutyryl adenosine 3',5'-cyclic monophosphate (dbcAMP) of steroid 21-hydroxylase activity in rat hepatocytes.
Topics: Animals; Bucladesine; Cells, Cultured; Colforsin; Isoquinolines; Liver; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Steroid 21-Hydroxylase; Tetradecanoylphorbol Acetate | 1994 |
Regulation of steroid production in ovarian stromal tissue from 5- to 8-week-old pullets and laying hens.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androstenedione; Animals; Calcimycin; Cells, Cultured; Chickens; Colforsin; Estradiol; Female; Gonadal Steroid Hormones; Luteinizing Hormone; Ovary; Progesterone; Sexual Maturation; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1994 |
Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.
Topics: Animals; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Ethers, Cyclic; Evoked Potentials; Exocytosis; Islets of Langerhans; Membrane Potentials; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1994 |
Phospholipases and melatonin signal transduction in the ovine pars tuberalis.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Choline; Colforsin; Cyclic AMP; Female; Lysophospholipids; Male; Melatonin; Membrane Lipids; Phosphatidic Acids; Phospholipases; Phospholipids; Pituitary Gland, Anterior; Second Messenger Systems; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Regulation of angiotensin II type 1 receptor mRNA in neuronal cultures of normotensive and spontaneously hypertensive rat brains by phorbol esters and forskolin.
Topics: Animals; Brain; Cells, Cultured; Colforsin; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Reference Values; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
5-Hydroxytryptamine type 2A receptors regulate cyclic AMP accumulation in a neuronal cell line by protein kinase C-dependent and calcium/calmodulin-dependent mechanisms.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alkaloids; Animals; Calcium; Calmodulin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Inositol Phosphates; Neurons; Protein Kinase C; Rats; Receptors, Serotonin; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Regulation of type 1 angiotensin II receptor messenger ribonucleic acid expression in human adrenocortical carcinoma H295 cells.
Topics: Adrenal Cortex Neoplasms; Angiotensin II; Base Sequence; Bucladesine; Calcimycin; Colforsin; Cyclic AMP; Cycloheximide; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Molecular Sequence Data; Phosphoric Diester Hydrolases; Receptors, Angiotensin; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Signal transduction in avian granulosa cells: effects of protein kinase C inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Chickens; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Synergism; Female; Granulosa Cells; Inositol Phosphates; Isoquinolines; Piperazines; Progesterone; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Calcium is involved in both positive and negative modulation of the secretory system for ANP.
Topics: Animals; Animals, Newborn; Atrial Natriuretic Factor; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cells, Cultured; Chromatography, High Pressure Liquid; Colforsin; Egtazic Acid; Endothelins; Fibroblast Growth Factors; Gallic Acid; Heart; Heart Atria; Kinetics; Models, Cardiovascular; Myocardium; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Ryanodine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1994 |
12-O-tetradecanoyl-phorbol-13-acetate (TPA) counteracts the cAMP up-regulation of the expression of the stimulatory guanine nucleotide binding protein (Gs alpha) and Gs alpha messenger RNA in cultured pig thyroid cells.
Topics: Adenylyl Cyclases; Animals; Blotting, Northern; Cells, Cultured; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; Gene Expression Regulation; GTP-Binding Proteins; Kinetics; Protein Kinase C; RNA, Messenger; Swine; Terpenes; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1994 |
A novel synergistic stimulation of Swiss 3T3 cells by extracellular ATP and mitogens with opposite effects on cAMP levels.
Topics: 3T3 Cells; Adenosine Triphosphate; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arachidonic Acid; Cell Division; Cell Nucleus; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; DNA; Drug Synergism; Epidermal Growth Factor; Kinetics; Lysophospholipids; Mice; Mitogens; Phosphatidic Acids; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine | 1994 |
Independent transcriptional and posttranscriptional regulation of the two tumor necrosis factor receptors in promyelocytic HL-60 cells.
Topics: Base Sequence; Bucladesine; Cell Membrane; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; DNA Primers; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Oligonucleotides, Antisense; Polymerase Chain Reaction; Protein Kinase C; Receptors, Tumor Necrosis Factor; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
[The influence of DPDPE on intracellular free calcium concentration induced by Bt2 cAMP and phorbol ester].
Topics: Calcium-Transporting ATPases; Colforsin; Cyclic AMP; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Humans; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil | 1993 |
Regulation of CYP11A gene expression in bovine ovarian granulosa cells in primary culture by cAMP and phorbol esters is conferred by a common cis-acting element.
Topics: Animals; Base Sequence; Cattle; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; DNA; Female; Gene Expression Regulation, Enzymologic; Genes, Reporter; Granulosa Cells; Molecular Sequence Data; Phorbol Esters; Protein Kinase C; RNA, Messenger; Second Messenger Systems; Steroid 17-alpha-Hydroxylase; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Modulators of the protein kinase C system influence biliary excretion of cationic drugs.
Topics: Alkaloids; Animals; Bile; Biological Transport, Active; Carrier Proteins; Cations; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Glucagon; In Vitro Techniques; Liver; Male; Perfusion; Protein Kinase C; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1993 |
An AP-1-like factor and the pituitary-specific factor Pit-1 are both necessary to mediate hormonal induction of human thyrotropin beta gene expression.
Topics: Base Sequence; Colforsin; DNA-Binding Proteins; Gene Expression Regulation; HeLa Cells; Humans; Molecular Sequence Data; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyrotropin; Thyrotropin-Releasing Hormone; Transcription Factor Pit-1; Transcription Factors | 1993 |
Distribution and regulation of natriuretic factor-R1C receptor subtypes in mammalian cell lines.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Cattle; Cell Line; Colforsin; Cyclic GMP; Humans; Mice; Natriuretic Peptide, C-Type; Nerve Tissue Proteins; Rats; Receptors, Atrial Natriuretic Factor; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Phorbol ester sequentially downregulates cAMP-regulated basolateral and apical Cl- transport pathways in T84 cells.
Topics: Biological Transport; Carrier Proteins; Cell Line; Cell Membrane; Chlorides; Colforsin; Colon; Cyclic AMP; Electrophysiology; Humans; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Activin-A regulates follistatin secretion from cultured rat anterior pituitary cells.
Topics: Activins; Animals; Cells, Cultured; Colforsin; Culture Media; Follistatin; Glycoproteins; Inhibins; Male; Pituitary Gland, Anterior; Rats; Tetradecanoylphorbol Acetate | 1993 |
Serotonin secretion from rat Leydig cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Dose-Response Relationship, Drug; Ionomycin; Leydig Cells; Male; Rats; Serotonin; Tetradecanoylphorbol Acetate | 1993 |
Differential regulation of inducible and constitutive prostaglandin endoperoxide synthase in osteoblastic MC3T3-E1 cells.
Topics: Animals; Cell Line; Colforsin; Culture Media; Culture Media, Serum-Free; Cycloheximide; Dactinomycin; Dinoprostone; DNA; Enzyme Induction; Hydrocortisone; Kinetics; Mice; Osteoblasts; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta | 1993 |
Isoproterenol- and insulin-induced hyperpolarization in rat skeletal muscle.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic GMP; Insulin; Isoproterenol; Male; Membrane Potentials; Muscles; Ouabain; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1993 |
Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity.
Topics: Animals; Base Sequence; Calcimycin; Cell Line; Colforsin; Cyclic AMP; DNA-Binding Proteins; Gene Expression Regulation; Insulin; Iodide Peroxidase; Kinetics; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Regulatory Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Transcription Factors; Transcription, Genetic; Transfection | 1993 |
cAMP-induced changes of intracellular free Mg2+ levels in human erythrocytes.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Colforsin; Cyclic AMP; Diphosphoglyceric Acids; Erythrocytes; Humans; In Vitro Techniques; Isoproterenol; Isoquinolines; Kinetics; Magnesium; Magnetic Resonance Spectroscopy; Protein Kinase Inhibitors; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Thyroperoxidase mRNA in quiescent and proliferating thyroid epithelial cells: expression and subcellular localization studied by in situ hybridization.
Topics: Animals; Cell Division; Cell Nucleus; Cells, Cultured; Colforsin; Cytoplasm; DNA; Dogs; Epidermal Growth Factor; Epithelial Cells; Epithelium; In Situ Hybridization; Interphase; Iodide Peroxidase; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroglobulin; Thyroid Gland; Thyrotropin | 1993 |
Na/H exchange activities in NHE1-transfected OK-cells: cell polarity and regulation.
Topics: Amiloride; Animals; Biological Transport; Blotting, Northern; Cell Line; Cell Membrane; Cell Polarity; Colforsin; Cyclic AMP-Dependent Protein Kinases; Humans; Immunoblotting; Kidney; Opossums; Parathyroid Hormone; Protein Kinase C; RNA, Messenger; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Modulation of parathyroid hormone-sensitive adenylate cyclase in ROS 17/2.8 cells by dexamethasone 1,25-dihydroxyvitamin D3 and protein kinase C.
Topics: Adenylyl Cyclases; Animals; Calcitriol; Colforsin; Dexamethasone; Enzyme Activation; Kinetics; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells. Effects of tumour necrosis factor alpha, interleukin 1 and phorbol ester.
Topics: Capillaries; Cells, Cultured; Colforsin; Endothelium, Vascular; Enzyme Induction; Extracellular Matrix; Fibroblasts; Humans; Interleukin-1; Metalloendopeptidases; RNA, Messenger; Synovial Membrane; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Veins | 1993 |
Differential effects of phorbol myristate acetate and dexamethasone on protein kinase C activity and eicosanoids production in cultured rat astrocytes.
Topics: Alkaloids; Animals; Astrocytes; Biomarkers; Cells, Cultured; Colforsin; Dexamethasone; Dinoprostone; Eicosanoids; Female; Fluorescent Antibody Technique; Neuroglia; Pregnancy; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Differential control of activin, inhibin and follistatin proteins in cultured rat granulosa cells.
Topics: Activins; Animals; Cells, Cultured; Colforsin; Female; Follicle Stimulating Hormone; Follistatin; Glycoproteins; Gonadotropin-Releasing Hormone; Granulosa Cells; Humans; Inhibins; Kinetics; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sexual Maturation; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Hormonal regulation, localization, and functional activity of the progesterone receptor in granulosa cells of rat preovulatory follicles.
Topics: Animals; Cells, Cultured; Colforsin; Corpus Luteum; Female; Fluorescent Antibody Technique; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Granulosa Cells; Luteinizing Hormone; Molecular Weight; Ovarian Follicle; Ovulation; Progesterone; Rats; Receptors, Progesterone; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Up-regulation of oxytocin receptors in rabbit amnion by adenosine 3',5'-monophosphate.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amnion; Animals; Bucladesine; Cholera Toxin; Colforsin; Cyclic AMP; Cycloheximide; Dinoprostone; Drug Synergism; Female; Isoquinolines; Oxytocin; Piperazines; Pregnancy; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Receptors, Angiotensin; Receptors, Oxytocin; Tetradecanoylphorbol Acetate; Up-Regulation | 1993 |
Phorbolester stimulates the activity of human corticotropin-releasing hormone gene promoter via 3',5'-cyclic adenosine monophosphate response element in transiently transfected chicken macrophages.
Topics: Animals; Base Sequence; Binding Sites; Chickens; Chloramphenicol O-Acetyltransferase; Colforsin; Consensus Sequence; Corticotropin-Releasing Hormone; Cyclic AMP; DNA; Genes, fos; Genes, jun; Macrophages; Promoter Regions, Genetic; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Transfection | 1993 |
Endothelins modulate dibutyryl cAMP-induced stellation of cultured astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Bucladesine; Calcium; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Egtazic Acid; Endothelins; Isoproterenol; Kinetics; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Time Factors; Viper Venoms | 1993 |
Cyclic adenosine 3',5'-monophosphate, a second messenger in interleukin-1 mediated K562 cytostasis.
Topics: Adenylyl Cyclases; Alkaloids; Bucladesine; Cell Division; Colforsin; Cyclic AMP; Humans; Interleukin-1; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Inhibition of human pancreatic cancer cell (MIA PaCa-2) growth by cholera toxin and 8-chloro-cAMP in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Drug Synergism; Epidermal Growth Factor; Humans; Immunologic Factors; Insulin-Like Growth Factor I; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Protein kinase C inhibits arginine vasopressin-stimulated cAMP accumulation via a Gi-dependent mechanism.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arginine Vasopressin; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Epidermal Growth Factor; GTP-Binding Proteins; Kidney Tubules, Collecting; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1993 |
Presence and possible involvement of Ca/calmodulin-dependent protein kinases in insulin release from the rat pancreatic beta cell.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Azepines; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Immunoblotting; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Isoquinolines; Kinetics; Male; Myosin-Light-Chain Kinase; Myosins; Phosphates; Phosphorus Radioisotopes; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diazoxide; Diterpenes; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Potassium; Potassium Channels; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1993 |
Ca2+ inhibition of beta-adrenergic receptor- and forskolin-stimulated cAMP accumulation in C6-2B rat glioma cells is independent of protein kinase C.
Topics: Animals; Calcium; Colforsin; Cyclic AMP; Enzyme Activation; Glioma; Hydrolysis; Isoproterenol; Phosphatidylinositols; Protein Kinase C; Rats; Receptors, Adrenergic, beta; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1993 |
Suppression by [D-Pen2, D-Pen5]enkephalin on cyclic AMP dependent protein kinase-induced, but not protein kinase C-induced increment of intracellular free calcium in NG108-15 cells.
Topics: Analgesics; Animals; Bucladesine; Calcium; Calcium Channels; Colforsin; Depression, Chemical; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glioma; Hybrid Cells; Intracellular Fluid; Mice; Neuroblastoma; Potassium Chloride; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Opioid, delta; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Involvement of the 3',5'-cyclic AMP pathway in the induction of calmodulin synthesis in myoblasts by 1,25(OH)2-vitamin D3.
Topics: Animals; Calcitriol; Calmodulin; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Lasalocid; Muscles; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1993 |
Cyclic adenosine monophosphate response in primary and subcultured bladder epithelial cells: inhibition by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Alkaloids; Animals; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dogs; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Epithelium; Indomethacin; Models, Biological; Protein Kinase C; Second Messenger Systems; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1993 |
Enhancement of the responsiveness of cortical adrenergic receptors by chronic administration of the 5-hydroxytryptamine uptake inhibitor citalopram.
Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Captopril; Cerebral Cortex; Citalopram; Colforsin; Cyclic AMP; Down-Regulation; Drug Administration Schedule; In Vitro Techniques; Isoproterenol; Kinetics; Male; Norepinephrine; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Second Messenger Systems; Selective Serotonin Reuptake Inhibitors; Tetradecanoylphorbol Acetate | 1993 |
Phorbol ester, prostaglandin E2, forskolin and okadaic acid differentially modulate interleukin-4-versus interleukin-2-dependent immunoglobulin induction in human cellular models, in contrast to other selected modifiers of cellular activation.
Topics: Antibodies, Monoclonal; B-Lymphocytes; Cells, Cultured; Colforsin; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Ethers, Cyclic; Humans; Immunoglobulin E; Immunoglobulin G; Immunoglobulins; Interleukin-2; Interleukin-4; Interleukins; Lymphocyte Activation; Okadaic Acid; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate | 1993 |
Vasopressin, unlike phorbol ester, fails to synergistically interact with pituitary adenylate cyclase activating polypeptide (PACAP) in stimulating cyclic AMP formation and ACTH secretion in cultured anterior pituitary cells.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Drug Interactions; Male; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland, Anterior; Protein Kinase C; Pyrrolidinones; Rats; Rats, Wistar; Rolipram; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Epidermal growth factor induces prolactin mRNA in GH4C1 cells via a protein synthesis-dependent pathway.
Topics: Animals; Bucladesine; Colforsin; Cycloheximide; Epidermal Growth Factor; Gene Expression Regulation; Pituitary Gland, Anterior; Prolactin; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Puromycin; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Protein kinase A activators inhibit agonist induced prostaglandin production in human amnion.
Topics: Adenylyl Cyclases; Amnion; Bucladesine; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; Female; Fetus; Humans; In Vitro Techniques; Isoproterenol; Oxytocin; Pregnancy; Pregnancy Trimester, Third; Protein Kinases; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Regulation of human renin secretion and renin transcription by quantitative PCR in cultured chorionic cells: synergistic effect of cyclic AMP and protein kinase C.
Topics: Base Sequence; Cells, Cultured; Chorion; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Exons; Gene Expression Regulation, Enzymologic; Humans; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Protein Kinase C; Renin; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1993 |
Regulation of endothelin 1 gene by fluid shear stress is transcriptionally mediated and independent of protein kinase C and cAMP.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Down-Regulation; Endothelins; Gene Expression Regulation; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Stress, Mechanical; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1993 |
Role of protein kinase A in LPS-induced activation of NF-kappa B proteins of a mouse macrophage-like cell line, J774.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Base Sequence; Bucladesine; Cholera Toxin; Colforsin; Consensus Sequence; Cyclic AMP; Dinoprostone; Female; Gene Expression Regulation, Neoplastic; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Phosphorylation; Piperazines; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription Factor RelB; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Regulation of expression of the CYP11A (P450scc) gene in bovine ovarian luteal cells by forskolin and phorbol esters.
Topics: Animals; Base Sequence; Binding, Competitive; Cattle; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Cloning, Molecular; Colforsin; Corpus Luteum; Cyclic AMP; DNA; Female; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Mutagenesis; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Role of intracellular calcium and protein kinases in the activation of hepatic Na+/taurocholate cotransport by cyclic AMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Colforsin; Cyclic AMP; Ionomycin; Kinetics; Liver; Phenylephrine; Protein Kinase Inhibitors; Protein Kinases; Rats; Sodium; Taurocholic Acid; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasopressins | 1993 |
Rapid and sustained phosphorylation of a calmodulin-binding protein (CaM-BP100) in NGF-treated PC12 cells.
Topics: Animals; Bradykinin; Brain; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Calmodulin-Binding Proteins; Carbachol; Cattle; Colforsin; Cyclic AMP; Cytosol; Epidermal Growth Factor; Fibroblast Growth Factor 2; Ionomycin; Kinetics; Nerve Growth Factors; PC12 Cells; Phosphorylation; Protein Kinases; Tetradecanoylphorbol Acetate; Thionucleotides | 1993 |
Competence induction by PDGF requires sustained calcium influx by a mechanism distinct from storage-dependent calcium influx.
Topics: Animals; Bucladesine; Calcium; Calcium Channels; Cell Compartmentation; Cell Division; Cell Line; Cell Membrane; Colforsin; Contact Inhibition; DNA Replication; Drug Synergism; Extracellular Space; Fibroblasts; Gallic Acid; Insulin; Ion Channel Gating; Lanthanum; Mice; Mice, Inbred C3H; Nifedipine; Platelet-Derived Growth Factor; S Phase; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
The signal transduction pathway for VGF expression due to NGF is different from that due to bFGF in PC12h cell.
Topics: Alkaloids; Animals; Bucladesine; Colforsin; Deoxyadenosines; Fibroblast Growth Factor 2; Heparin; Molecular Weight; Nerve Growth Factors; PC12 Cells; Potassium Chloride; Protein Biosynthesis; Protein Kinase C; Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleosides | 1993 |
Parathyroid hormone increases cytosolic calcium of thymocytes.
Topics: Animals; Bucladesine; Calcium; Colforsin; Cytosol; In Vitro Techniques; Male; Parathyroid Hormone; Peptide Fragments; Rats; Rats, Sprague-Dawley; T-Lymphocytes; Teriparatide; Tetradecanoylphorbol Acetate; Uremia; Verapamil | 1993 |
Characterization and regulation of corticotropin-releasing factor in the human hepatoma NPLC-KC cell line.
Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Carcinoma, Hepatocellular; Colforsin; Corticotropin-Releasing Hormone; Culture Media, Conditioned; Dexamethasone; Humans; Interleukin-1; Liver Neoplasms; Pituitary Gland, Anterior; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Insulin-like growth factor-II in human fetal adrenals: regulation by ACTH, protein kinase C and growth factors.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Alkaloids; Blotting, Northern; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Gene Expression; Gene Expression Regulation; Genes; Growth Substances; Humans; Insulin-Like Growth Factor II; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1993 |
Dopamine stimulates K+ efflux in the chick retina via D1 receptors independently of adenylyl cyclase activation.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Chickens; Colforsin; Dopamine; Dose-Response Relationship, Drug; Enzyme Activation; Male; Nucleotides, Cyclic; Potassium; Receptors, Dopamine D1; Retina; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Phospholipase C isozymes and modulation by cAMP-dependent protein kinase.
Topics: Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Humans; Isoenzymes; Second Messenger Systems; T-Lymphocytes; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1993 |
12-O-tetradecanoylphorbol-13-acetate-induced inhibition of gap junctional communication is differentially regulated in a transformation-sensitive Syrian hamster embryo cell line compared to early passage SHE cells.
Topics: Animals; Cell Communication; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Down-Regulation; Embryo, Mammalian; Epidermal Growth Factor; Gap Junctions; Mesocricetus; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Protein kinase C and adenylate cyclase as targets for growth inhibition of human gastric cancer cells.
Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alkaloids; Bucladesine; Cell Division; Colforsin; Enzyme Activation; Humans; Protein Kinase C; Staurosporine; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Expression pattern of proteins that bind to the ultraviolet-responsive element (TGACAACA) in human keratinocytes.
Topics: Animals; Antibodies; Base Sequence; Cell Cycle; Colforsin; Fibroblasts; Gene Expression; Genes, jun; Humans; Keratinocytes; Mice; Molecular Sequence Data; Molecular Weight; Nuclear Proteins; Oligonucleotides; Protein Binding; Proto-Oncogene Proteins c-jun; Rats; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1993 |
Regulation of arginine vasopressin mRNA in rat fetal hypothalamic cell culture. Role of protein kinases and glucocorticoids.
Topics: Animals; Arginine Vasopressin; Cells, Cultured; Colforsin; Dexamethasone; Down-Regulation; Fetus; Gene Expression Regulation; Hypothalamus; In Situ Hybridization; Protein Kinase C; Protein Kinases; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1993 |
P2 purinergic agonists and 12-O-tetradecanoylphorbol-13-acetate, as well as protein kinase A activators, stimulate thyroglobulin secretion in FRTL-5 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Diphosphate; Adenosine Triphosphate; Cells, Cultured; Colforsin; Enzyme Activation; Guanosine Triphosphate; Protein Kinases; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Thyroglobulin | 1993 |
Characterization of the mouse carbonic anhydrase II gene promoter.
Topics: 3T3 Cells; Animals; Base Sequence; Carbonic Anhydrases; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; Colforsin; Deoxyribonucleases, Type II Site-Specific; DNA; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Restriction Mapping; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Differential effects of activation of protein kinase C and cyclic-AMP-dependent protein kinase on sodium-dependent phosphate uptake in NIH 3T3 cells.
Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Carrier Proteins; Cholera Toxin; Colforsin; Enzyme Activation; Kinetics; Mice; Models, Biological; Phosphate-Binding Proteins; Phosphates; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Sodium; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Structural and functional characterization of the rat follistatin (activin-binding protein) gene promoter.
Topics: Activins; Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; Colforsin; Female; Follistatin; Gene Expression Regulation; Genes; Genes, Synthetic; Glycoproteins; Granulosa Cells; Inhibins; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; RNA Caps; Tetradecanoylphorbol Acetate | 1993 |
Complex interactions among second messenger pathways, steroid hormones, and protooncogenes of the Fos and Jun families converge in the regulation of the nerve growth factor gene.
Topics: Animals; Base Sequence; Blood; Calcitriol; Colforsin; Dexamethasone; Gene Expression Regulation; Molecular Sequence Data; Nerve Growth Factors; Oligonucleotide Probes; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1993 |
Requirements for the induction of the interleukin-2 receptor complex in a human pre-T-cell line.
Topics: Cell Line; Colforsin; Humans; Infant; Interleukin-1; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Interleukin-2; Recombinant Proteins; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Rapid agonist-mediated phosphorylation of m3-muscarinic receptors revealed by immunoprecipitation.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Atropine; Base Sequence; Carbachol; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Electrophoresis, Polyacrylamide Gel; Glutathione Transferase; Humans; Immune Sera; Immunoblotting; Ionomycin; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Parasympathomimetics; Phosphates; Phosphorylation; Plasmids; Polymerase Chain Reaction; Protein Kinases; Receptors, Muscarinic; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Phosphorylation of neuronal kinesin heavy and light chains in vivo.
Topics: Amino Acids; Animals; Autoradiography; Calcium; Cells, Cultured; Chick Embryo; Colforsin; Electrophoresis, Polyacrylamide Gel; Ganglia, Sympathetic; Kinesins; Macromolecular Substances; Molecular Weight; Neurons; PC12 Cells; Peptide Fragments; Peptide Mapping; Phosphorus Radioisotopes; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Trypsin | 1993 |
Expression of bone morphogenic protein 7 mRNA in MDCK cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Base Sequence; Bone Morphogenetic Proteins; Cells, Cultured; Colforsin; DNA; Dogs; Growth Substances; Humans; Kidney; Molecular Sequence Data; Protein Kinase C; Protein Kinases; Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate | 1993 |
Regulation of gonadotropin-releasing hormone by protein kinase-A and -C in immortalized hypothalamic neurons.
Topics: Animals; Base Sequence; Cell Line, Transformed; Colforsin; Gonadotropin-Releasing Hormone; Hypothalamus; Molecular Sequence Data; Neurons; Oligonucleotide Probes; Piperidines; Protein Kinase C; Protein Kinases; Protein Precursors; Protein Processing, Post-Translational; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1993 |
Continuous monitoring of nitric oxide release from human umbilical vein endothelial cells.
Topics: Alkaloids; Arginine; Bradykinin; Cells, Cultured; Colforsin; Endothelium, Vascular; Enzyme Activation; Humans; Ionomycin; Kinetics; Nitric Oxide; Polarography; Protein Kinase C; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Umbilical Veins | 1993 |
Corticotropin-releasing factor (CRF) and glucocorticoids modulate the expression of type 1 CRF receptor messenger ribonucleic acid in rat anterior pituitary cell cultures.
Topics: Animals; Arginine Vasopressin; Base Sequence; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Glucocorticoids; Male; Molecular Sequence Data; Oligonucleotide Probes; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Tetradecanoylphorbol Acetate | 1996 |
Vesicular monoamine uptake by digitonin-permeabilized PC12 cells: inhibitory effect of neuromodulators and drugs on the amine transport.
Topics: Adenosine Monophosphate; Animals; Biogenic Monoamines; Biological Transport; Cell Membrane Permeability; Colforsin; Digitoxin; Nomifensine; PC12 Cells; Rats; Reserpine; Serotonin; Tetradecanoylphorbol Acetate | 1995 |
The role and proposed mechanism by which oestradiol 17 beta-hydroxysteroid dehydrogenase regulates breast tumour oestrogen concentrations.
Topics: Breast; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol Dehydrogenases; Estrogens; Female; Gene Expression Regulation, Enzymologic; Humans; NADP; Naphthalenes; Protein Kinase C; Receptors, Estrogen; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Activators of protein kinase C but not of phospholipase C modulate adenylate cyclase-responses of normal pig epidermis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adenylyl Cyclases; Animals; Bradykinin; Cell Division; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epidermal Cells; Epidermal Growth Factor; Epidermis; Epinephrine; Histamine; Isoquinolines; Keratinocytes; Piperazines; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1995 |
Expression and regulation of vascular endothelial growth factor in choroidal fibroblasts.
Topics: Aged; Blotting, Northern; Blotting, Western; Carcinogens; Cells, Cultured; Choroid; Colforsin; Cyclic AMP; Cytokines; Endothelial Growth Factors; Enzyme Activation; Fibroblasts; Gene Expression Regulation; Humans; Lymphokines; Middle Aged; Pigment Epithelium of Eye; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1995 |
Down-regulation and differential restoration of cAMP responses upon transient phorbol ester treatment of primary osteoblastic cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dinoprostone; Down-Regulation; Enzyme Activation; Kinetics; Osteoblasts; Parathyroid Hormone; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Receptors, Parathyroid Hormone; Signal Transduction; Skull; Tetradecanoylphorbol Acetate | 1995 |
Genes related to growth and invasiveness are repressed by sodium butyrate in ovarian carcinoma cells.
Topics: Adenylyl Cyclases; Butyrates; Butyric Acid; Cell Division; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Cyclins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Isoquinolines; Neoplasm Invasiveness; Oncogene Proteins; Oncogenes; Ovarian Neoplasms; Protein Kinase C; Proteins; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 1996 |
A phorbol ester that activates protein kinase C mimics the action of estradiol or epidermal growth factor for initiating embryo implantation in the delayed implanting hypophysectomized rat.
Topics: Animals; Blastomeres; Cholera Toxin; Colforsin; Cyclic AMP; Embryo Implantation, Delayed; Enzyme Activation; Estrogens; Female; Hypophysectomy; Insulin-Like Growth Factor I; Male; Phosphorylation; Pituitary Gland; Pregnancy; Progesterone; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Cyclic AMP stimulates protein synthesis in L6 myoblasts and its effects are additive to those of insulin, vasopressin and 12-0-tetradecanoylphorbol-13-acetate. Possible involvement of mitogen activated protein kinase.
Topics: Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Enzyme Activation; Insulin; Molecular Weight; Muscle Fibers, Skeletal; Myelin Basic Protein; Protein Biosynthesis; Rats; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Vasopressins | 1996 |
Glucagon induces a rapid and sustained phosphorylation of the human glucagon receptor in Chinese hamster ovary cells.
Topics: Amino Acid Sequence; Animals; Antibodies; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Glucagon; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Phosphates; Phosphoproteins; Phosphorylation; Phosphoserine; Protein Kinase C; Receptors, Glucagon; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 1996 |
The actions of prostaglandin E2 on potassium currents in rat tail artery vascular smooth muscle cells: regulation by protein kinase A and protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Male; Muscle, Smooth, Vascular; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Tail; Tetradecanoylphorbol Acetate | 1996 |
Regulation of the nuclear factor of activated T cells in stably transfected Jurkat cell clones.
Topics: Alkaline Phosphatase; Bucladesine; Clone Cells; Colforsin; Cyclosporine; Dinoprostone; DNA-Binding Proteins; Enzyme Inhibitors; Ethers, Cyclic; Female; Humans; Immunosuppressive Agents; Kinetics; Lymphocyte Activation; Marine Toxins; NFATC Transcription Factors; Nuclear Proteins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Placenta; Pregnancy; Protein Phosphatase 1; Recombinant Proteins; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1996 |
The seven-transmembrane-spanning receptors for endothelin and thrombin cause proliferation of airway smooth muscle cells and activation of the extracellular regulated kinase and c-Jun NH2-terminal kinase groups of mitogen-activated protein kinases.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Endothelins; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Muscle, Smooth; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Receptors, Cell Surface; Receptors, Endothelin; Receptors, Thrombin; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Thrombin; Thymidine; Trachea | 1996 |
Induction of primate TH2 lymphokines to suppress TH1 cells.
Topics: Animals; Cells, Cultured; Cholera Toxin; Colforsin; Enzyme Activation; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Interleukin-2; Interleukin-4; Ionomycin; Lymphokines; Papio; Protein Kinase C; Tacrolimus; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells; Virulence Factors, Bordetella | 1996 |
Shedding of human thyrotropin receptor ectodomain. Involvement of a matrix metalloprotease.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Endocytosis; Extracellular Matrix; Humans; Hydroxamic Acids; Kinetics; L Cells; Lysosomes; Macromolecular Substances; Metalloendopeptidases; Mice; Protease Inhibitors; Receptors, Thyrotropin; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thyroid Gland; Transfection | 1996 |
Induction of proenkephalin gene expression in cultured bovine chromaffin cells is dependent on protein synthesis of AP-1 proteins.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cattle; Cells, Cultured; Chromaffin System; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Enkephalins; Gene Expression Regulation; Genes, Immediate-Early; Genes, Reporter; Kinetics; Molecular Sequence Data; Nuclear Proteins; Oligonucleotides; Peptide Fragments; Phosphorylation; Potassium Chloride; Protein Kinase C; Protein Precursors; Proto-Oncogene Proteins c-fos; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1 | 1996 |
Transduction mechanisms involved in thrombin receptor-induced nerve growth factor secretion and cell division in primary cultures of astrocytes.
Topics: Adenylyl Cyclase Inhibitors; Animals; Astrocytes; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Female; GTP-Binding Proteins; Nerve Growth Factors; Peptide Fragments; Pertussis Toxin; Pregnancy; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Thrombin; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thymidine; Tritium; Virulence Factors, Bordetella | 1996 |
Protein kinase C modulates natriuretic peptide receptors in astroglial cultures from rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Animals, Newborn; Astrocytes; Atrial Natriuretic Factor; Binding Sites; Brain Stem; Cells, Cultured; Colforsin; Cyclic GMP; Down-Regulation; Enzyme Inhibitors; Hypothalamus; Kinetics; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor; Staurosporine; Tetradecanoylphorbol Acetate; Up-Regulation | 1996 |
Effects of prostaglandins on deoxyribonucleic acid and aggrecan synthesis in the RCJ 3.1C5.18 chondrocyte cell line: role of second messengers.
Topics: Aggrecans; Alprostadil; Animals; Bucladesine; Calcium; Cartilage; Cell Line; Colforsin; Cyclic AMP; Dinoprost; Dinoprostone; DNA; Extracellular Matrix Proteins; Lectins, C-Type; Prostaglandins; Protein Kinase C; Proteoglycans; Rats; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1996 |
c-Myc expression is controlled by the mitogenic cAMP-cascade in thyrocytes.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; Colforsin; Cyclic AMP; Dogs; Gene Expression Regulation; Genes, myc; Hepatocyte Growth Factor; Molecular Sequence Data; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Transcription, Genetic | 1996 |
Regulation of expression of the steroidogenic acute regulatory (StAR) protein by ACTH in bovine adrenal fasciculata cells.
Topics: Adrenocorticotropic Hormone; Animals; Bucladesine; Calcimycin; Cattle; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Hydrocortisone; Immunohistochemistry; Isoquinolines; Kinetics; Naphthalenes; Phosphoproteins; Quinazolines; Sulfonamides; Tetradecanoylphorbol Acetate; Zona Fasciculata | 1996 |
The proteinase-activated receptor 2 is induced by inflammatory mediators in human endothelial cells. Comparison with the thrombin receptor.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Chlorocebus aethiops; Colforsin; DNA Probes; Down-Regulation; Endothelium, Vascular; Humans; Inflammation; Interleukin-1; Kinetics; Lipopolysaccharides; Receptor, PAR-2; Receptors, Cell Surface; Receptors, Thrombin; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha; Umbilical Veins | 1996 |
In vitro pituitary GH secretion after GHRH, forskolin, dibutyryl cyclic-adenosine 3',5'-monophosphate and phorbol 12-myristate 13-acetate stimulation in long-term orchidectomized rats.
Topics: Animals; Bucladesine; Colforsin; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; In Vitro Techniques; Kinetics; Male; Orchiectomy; Pituitary Gland; Prolactin; Rats; Rats, Wistar; Reference Values; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Evidence for coordinated regulation of osteoblast function by 1,25-dihydroxyvitamin D3 and parathyroid hormone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bucladesine; Calcitriol; Calcium; Calcium Channel Agonists; Cell Line; Colforsin; Cyclic AMP; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Activation; Humans; Osteoblasts; Osteocalcin; Parathyroid Hormone; Protein Kinase C; Rats; Receptors, Calcitriol; RNA, Messenger; Signal Transduction; Steroid Hydroxylases; Tetradecanoylphorbol Acetate; Up-Regulation; Vitamin D3 24-Hydroxylase | 1996 |
Dopamine D1A receptor regulation of phospholipase C isoform.
Topics: Animals; Base Sequence; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Enzyme Activation; Fenoldopam; Humans; Hydrolysis; Isoenzymes; Molecular Sequence Data; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Rats; Receptors, Dopamine D1; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
CCAAT/enhancer-binding protein alpha activation of the rat growth hormone promoter in pituitary progenitor GHFT1-5 cells.
Topics: Animals; Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Line; Colforsin; DNA-Binding Proteins; Growth Hormone; Humans; Molecular Sequence Data; Nuclear Proteins; Oligodeoxyribonucleotides; Pituitary Gland; Promoter Regions, Genetic; Protein Binding; Rats; Stem Cells; Tetradecanoylphorbol Acetate | 1996 |
Domain-specific gene activation by parathyroid hormone in osteoblastic ROS17/2.8 cells.
Topics: Animals; Blotting, Northern; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA Replication; DNA, Complementary; Gene Expression Regulation; Genes, Immediate-Early; Genetic Markers; Nucleic Acid Hybridization; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Protein Kinase C; Rats; Teriparatide; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1996 |
Effects of parathyroid hormone and agonists of the adenylyl cyclase and protein kinase C pathways on bone cell proliferation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Division; Cells, Cultured; Colforsin; Culture Techniques; Enzyme Activation; Mice; Mice, Inbred ICR; Molecular Sequence Data; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Protein Kinase C; Signal Transduction; Teriparatide; Tetradecanoylphorbol Acetate | 1996 |
Pharmacological studies on mechanisms involved in Ca2+ oscillations in rat megakaryocytes.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Female; Indoles; Male; Megakaryocytes; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Drug-induced reversion of progression phenotype is accompanied by reversion of AP-1 phenotype in JB6 cells.
Topics: 3T3 Cells; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Colforsin; Epidermal Growth Factor; Fluocinolone Acetonide; Glucocorticoids; Mice; Phenotype; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection | 1996 |
Phorbol ester activation of chloride current in guinea-pig ventricular myocytes.
Topics: Animals; Anions; Anthracenes; Chloride Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Heart Ventricles; Myocardium; Protein Kinase C; Sodium; Tetradecanoylphorbol Acetate | 1996 |
Regulatory properties of the integrated long terminal repeat of the feline immunodeficiency virus.
Topics: Animals; Azacitidine; Cats; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Gene Expression Regulation; Immunodeficiency Virus, Feline; Repetitive Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate | 1996 |
Interaction of cyclic AMP- and calcium-dependent mechanisms in the regulation of growth hormone-releasing hormone-stimulated growth hormone release from ovine pituitary cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Calmodulin; Cell Separation; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pituitary Gland; Potassium Chloride; Sheep; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Verapamil | 1996 |
Effects of corticotropin-releasing hormone, lysine vasopressin, oxytocin, and angiotensin II on adrenocorticotropin secretion from porcine anterior pituitary cells.
Topics: Adrenocorticotropic Hormone; Alkaloids; Angiotensin II; Animals; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Drug Synergism; Lypressin; Oxytocin; Pituitary Gland, Anterior; Protein Kinase C; Radioimmunoassay; Signal Transduction; Staurosporine; Swine; Tetradecanoylphorbol Acetate | 1996 |
Activation of a reporter gene responsive to NGFI-B in cultured neurons and astrocytes.
Topics: Animals; Astrocytes; Base Sequence; beta-Galactosidase; Binding Sites; Cells, Cultured; Cerebellum; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Gene Expression Regulation; Genes, Immediate-Early; Luciferases; Molecular Sequence Data; Neurons; Nuclear Receptor Subfamily 4, Group A, Member 1; Oligodeoxyribonucleotides; Phosphatidylethanolamines; Promoter Regions, Genetic; Protein Kinase C; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection | 1995 |
Cyclic-AMP deficient MDCK cells form tubules.
Topics: Ammonium Chloride; Animals; Cell Line; Clone Cells; Colforsin; Cyclic AMP; Dogs; Karyotyping; Kidney Tubules; Models, Biological; Morphogenesis; Signal Transduction; Tetradecanoylphorbol Acetate | 1995 |
Regulation of secretogranin II mRNA in rat neuronal cultures.
Topics: Animals; Animals, Newborn; Blotting, Northern; Brain Stem; Cells, Cultured; Chromogranins; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypothalamus; Kinetics; Nerve Growth Factors; Neurons; PC12 Cells; Potassium Chloride; Protein Biosynthesis; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Inhibition of T lymphocyte activation by cAMP is associated with down-regulation of two parallel mitogen-activated protein kinase pathways, the extracellular signal-related kinase and c-Jun N-terminal kinase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Indoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Leukemia-Lymphoma, Adult T-Cell; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphoma, T-Cell; Maleimides; Mice; Mitogen-Activated Protein Kinases; Mitogens; Molecular Sequence Data; Muromonab-CD3; Nerve Tissue Proteins; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Rapid stimulation of EAAC1-mediated Na+-dependent L-glutamate transport activity in C6 glioma cells by phorbol ester.
Topics: Adenylyl Cyclases; Amiloride; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Calcimycin; Carrier Proteins; Colforsin; Enzyme Inhibitors; Ethers, Cyclic; Excitatory Amino Acid Transporter 3; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glycine; Kinetics; Okadaic Acid; Phosphoric Monoester Hydrolases; Protein Kinase C; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Symporters; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Differential effects of forskolin and phorbol-13-myristate injected intrathecally or intracerebroventricularly on antinociception induced by morphine or beta-endorphin administered intracerebroventricularly in the mouse.
Topics: Adenylyl Cyclases; Analgesia; Animals; beta-Endorphin; Colforsin; Enzyme Activation; Injections, Intraventricular; Injections, Spinal; Kinetics; Male; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Protein Kinase C; Tetradecanoylphorbol Acetate | 1996 |
Regulation of 11 beta-hydroxysteroid dehydrogenase type 2 activity and mRNA in human choriocarcinoma cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Base Sequence; Bucladesine; Choriocarcinoma; Colforsin; Colon; Cyclic AMP-Dependent Protein Kinases; Female; Gene Expression Regulation, Enzymologic; Humans; Hydroxysteroid Dehydrogenases; Isoenzymes; Kidney; Kinetics; Oligonucleotides, Antisense; Organ Specificity; Placenta; Pregnancy; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Trophoblasts; Tumor Cells, Cultured; Uterine Neoplasms | 1996 |
Molecular cloning of c-jun and c-fos cDNAs from porcine anterior pituitary and their involvement in gonadotropin-releasing hormone stimulation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; Cloning, Molecular; Colforsin; DNA, Complementary; Follicle Stimulating Hormone; Gene Expression; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Molecular Sequence Data; Pituitary Gland, Anterior; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Sequence Homology, Amino Acid; Swine; Tetradecanoylphorbol Acetate | 1996 |
Angiotensin II type 1 receptor signals through Raf-1 by a protein kinase C-dependent, Ras-independent mechanism.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Aorta; beta-Galactosidase; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Enzyme Activation; Gene Expression Regulation; Genes, fos; Genes, Reporter; Humans; Kinetics; Luciferases; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Pertussis Toxin; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection; Virulence Factors, Bordetella | 1996 |
Interactions between signaling pathways in mediating GnRH-stimulated GTH release from goldfish pituitary cells: protein kinase C, but not cyclic AMP is an important mediator of GnRH-stimulated gonadotropin secretion in goldfish.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Arachidonic Acid; Calcium Channel Agonists; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Goldfish; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Male; Microspheres; Naphthalenes; Pituitary Gland; Potassium; Protein Kinase C; Salmon; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Inhibition of microglial superoxide anion production by isoproterenol and dexamethasone.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Blotting, Western; Cells, Cultured; Colforsin; Cricetinae; Cyclic AMP; Cytochrome c Group; Depression, Chemical; Dexamethasone; Isoproterenol; Microglia; Propranolol; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Modulation of cyclic AMP accumulation in glial cells by exogenous phospholipase C.
Topics: Adenylate Cyclase Toxin; Astrocytoma; Colforsin; Cyclic AMP; Down-Regulation; Glioma; Humans; Isoproterenol; Lysophospholipids; Neuroglia; Pertussis Toxin; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Pituitary follistatin and inhibin subunit messenger ribonucleic acid levels are differentially regulated by local and hormonal factors.
Topics: Activins; Animals; Colforsin; Follistatin; Glycoproteins; Gonadotropin-Releasing Hormone; Hormones; Inhibins; Male; Oligopeptides; Peptides; Pituitary Gland; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate | 1996 |
Mifepristone modulation of ACTH and CRH regulation of bovine adrenocorticosteroidogenesis in vitro.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Animals; Arginine Vasopressin; Cattle; Colforsin; Corticotropin-Releasing Hormone; Cosyntropin; Enzyme Inhibitors; Kinetics; Male; Mifepristone; Progesterone; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate | 1996 |
Desensitization of 5-hydroxytryptamine-facilitated dopamine release in vivo.
Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dopamine; Male; Microdialysis; Neostriatum; Protein Kinase C; Rats; Serotonin; Serotonin Receptor Agonists; Tetradecanoylphorbol Acetate | 1996 |
Multiple phosphorylation sites are required for pathway-selective uncoupling of the 5-hydroxytryptamine1A receptor by protein kinase C.
Topics: Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Protein Kinase C; Receptors, Serotonin; Sensitivity and Specificity; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1995 |
Transcriptional regulation and cell specificity determinants of the rat nicotinic acetylcholine receptor alpha 3 gene.
Topics: Animals; Carcinogens; Colforsin; Cyclic AMP; Gene Expression Regulation; PC12 Cells; Promoter Regions, Genetic; Protein Kinase C; Rats; Receptors, Nicotinic; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1996 |
Modulation of islet G-proteins, alpha-glucosidehydrolase inhibition and insulin release stimulated by various secretagogues.
Topics: 1-Deoxynojirimycin; 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Cholera Toxin; Clonidine; Colforsin; Enzyme Inhibitors; Female; Glucosamine; Glucose; Glycoside Hydrolases; GTP-Binding Proteins; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mannoheptulose; Mice; Pertussis Toxin; Phosphodiesterase Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1996 |
Interleukin-1 beta and tumor necrosis factor-alpha induce expression of alpha 1-antichymotrypsin in human astrocytoma cells by activation of nuclear factor-kappa B.
Topics: alpha 1-Antichymotrypsin; Astrocytoma; Blotting, Northern; Bucladesine; Cell Line; Colforsin; Gene Expression Regulation, Neoplastic; Humans; Interleukin-1; NF-kappa B; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Pituitary adenylate cyclase-activating peptide, carbachol, and glucose stimulate insulin release in the absence of an increase in intracellular Ca2+.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Cells, Cultured; Colforsin; Glucose; Insulin; Insulin Secretion; Intracellular Fluid; Islets of Langerhans; Neuropeptides; Nitrendipine; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Differential regulation of 11 beta-hydroxylase and aldosterone synthase in human adrenocortical H295R cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Cortex; Angiotensin II; Base Sequence; Bucladesine; Calcium Channel Agonists; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 CYP11B2; Gene Expression Regulation; Humans; Molecular Sequence Data; Nifedipine; Potassium; Protein Kinase C; Steroid 11-beta-Hydroxylase; Tetradecanoylphorbol Acetate | 1996 |
Inhibition of p70/p85 S6 kinase activities in T cells by dexamethasone.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Animals; Anti-Inflammatory Agents; Colforsin; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucocorticoids; Interleukin-2; Marine Toxins; Mice; Oxazoles; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Protein Kinase C; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; RNA, Messenger; Sirolimus; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1996 |
Parathyroid hormone regulates osteoblast differentiation positively or negatively depending on the differentiation stages.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Blotting, Northern; Bone Marrow Cells; Bucladesine; Cell Count; Cell Differentiation; Cells, Cultured; Colforsin; Colony-Forming Units Assay; DNA; Dose-Response Relationship, Drug; Humans; Hydroxyproline; Mice; Osteoblasts; Osteocalcin; RNA, Messenger; Staining and Labeling; Teriparatide; Tetradecanoylphorbol Acetate | 1996 |
Comparison of neurotrophin regulation of human and rat neuropeptide Y (NPY) neurons: induction of NPY production in aggregate cultures derived from rat but not from human fetal brains.
Topics: Abortion, Induced; Animals; Astrocytes; Brain; Brain-Derived Neurotrophic Factor; Cell Aggregation; Cells, Cultured; Colforsin; Female; Fetus; Gestational Age; Humans; Nerve Growth Factors; Neurons; Neuropeptide Y; Neurotrophin 3; Pregnancy; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; Recombinant Proteins; Species Specificity; Tetradecanoylphorbol Acetate | 1996 |
Binding of the inward rectifier K+ channel Kir 2.3 to PSD-95 is regulated by protein kinase A phosphorylation.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Calcimycin; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Humans; Kidney; Mammals; Molecular Sequence Data; Nerve Tissue Proteins; Peptide Fragments; Phosphorylation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Homologous regulation of the rat C1a calcitonin receptor (CTR) in nonosteoclastic cells is independent of CTR messenger ribonucleic acid changes and cyclic adenosine 3',5'-monophosphate-dependent protein kinase activation.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Calcitonin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Humans; Kidney; Kinetics; Osteosarcoma; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Receptors, Calcitonin; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1996 |
Ca2+/calmodulin and cyclic 3,5' adenosine monophosphate control movement of secretory granules through protein phosphorylation/dephosphorylation in the pancreatic beta-cell.
Topics: Acetylcholine; Animals; Calcium; Calmodulin; Cell Line; Chelating Agents; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Granules; Egtazic Acid; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Potassium; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate; Tolbutamide | 1996 |
Calcitonin-induced changes in the cytoskeleton are mediated by a signal pathway associated with protein kinase A in osteoclasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Animals, Newborn; Bucladesine; Calcitonin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Dentin; Enzyme Activation; Hematopoietic Stem Cells; Male; Mice; Mice, Inbred Strains; Osteoblasts; Phorbol 12,13-Dibutyrate; Protein Kinase C; Signal Transduction; Skull; Tetradecanoylphorbol Acetate; Thionucleotides | 1996 |
Induction of nerve growth factor-induced gene-B (NGFI-B) as an early event in the cyclic adenosine monophosphate response of dog thyrocytes in primary culture.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; Colforsin; Conserved Sequence; Cyclic AMP; DNA-Binding Proteins; Dogs; Epidermal Growth Factor; Gene Expression Regulation; Gene Library; Humans; In Vitro Techniques; Mice; Molecular Sequence Data; Nuclear Receptor Subfamily 4, Group A, Member 1; Promoter Regions, Genetic; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Transcription Factors; Transcription, Genetic; Xenopus | 1996 |
Differential effects of gonadotropin-releasing hormone, dopamine and somatostatin and their second messengers on the mRNA levels of gonadotropin II beta subunit and growth hormone in the teleost fish, tilapia.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dopamine; Enzyme Activation; Gonadotropin-Releasing Hormone; Gonadotropins; Growth Hormone; Pituitary Gland; Protein Kinase C; RNA, Messenger; Salmon; Second Messenger Systems; Somatostatin; Tetradecanoylphorbol Acetate; Tilapia | 1996 |
Nitric oxide donor SIN-1 inhibits insulin release.
Topics: Aluminum Compounds; Animals; Calcium-Transporting ATPases; Carbachol; Cells, Cultured; Colforsin; Cyclic AMP; Dithiothreitol; Fluorides; Glucose; GTP-Binding Proteins; Insulin; Insulin Secretion; Islets of Langerhans; Molsidomine; Nitric Oxide; Oxidation-Reduction; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Secretory Rate; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Phorbol ester, but not endotoxin, desensitizes mannan-induced glycogenolysis in the perfused rat liver.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aprotinin; Calcimycin; Colforsin; Enzyme Inhibitors; Escherichia coli; Leupeptins; Lipopolysaccharides; Liver; Liver Glycogen; Male; Mannans; Norepinephrine; Perfusion; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Effect of adenosine on phorbol myristate acetate induced-reactive oxygen metabolite production in cultured mesangial cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Colforsin; Cyclic AMP; Female; Glomerular Mesangium; Luminescent Measurements; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1996 |
Interactions between secretin and acetylcholine in the regulation of fluid secretion by isolated rat pancreatic ducts.
Topics: Acetylcholine; Animals; Calcium; Colforsin; Cyclic AMP; Enzyme Inhibitors; In Vitro Techniques; Ionomycin; Ionophores; Pancreatic Ducts; Pancreatic Juice; Protein Kinase C; Rats; Second Messenger Systems; Secretin; Signal Transduction; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1996 |
Dexamethasone represses phorbol ester-, forskolin-, and calcium-stimulated expression of a preproenkephalin A promoter-chloramphenicol acetyltransferase gene via a receptor-mediated mechanism.
Topics: Calcimycin; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Depression, Chemical; Dexamethasone; Enkephalins; Gene Expression Regulation, Enzymologic; Genes, Reporter; Glucocorticoids; Humans; Ionophores; Promoter Regions, Genetic; Protein Precursors; Receptors, Glucocorticoid; Tetradecanoylphorbol Acetate | 1996 |
Molecular mechanisms underlying the regulation of proenkephalin gene expression in cultured spinal cord cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dexamethasone; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Mollusk Venoms; Nimodipine; Protein Kinase C; Protein Precursors; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Second Messenger Systems; Signal Transduction; Spinal Cord; Tetradecanoylphorbol Acetate | 1996 |
Binding of CD44 to hyaluronic acid can be induced by multiple signals and requires the CD44 cytoplasmic domain.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; CD3 Complex; Colchicine; Colforsin; Cyclic AMP; Cycloheximide; Cytochalasin D; Cytoplasm; Cytoskeletal Proteins; Cytoskeleton; Humans; Hyaluronan Receptors; Hyaluronic Acid; Ionomycin; Ionophores; Jurkat Cells; Molecular Sequence Data; Mutagenesis, Site-Directed; Paclitaxel; Protein Biosynthesis; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Signal transduction pathways mediating parathyroid hormone stimulation of bone sialoprotein gene expression in osteoblasts.
Topics: Animals; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Gene Expression Regulation; Ionomycin; Osteoblasts; Parathyroid Hormone; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Second Messenger Systems; Sialoglycoproteins; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Human stem cell factor promoter deoxyribonucleic acid sequence and regulation by cyclic 3',5'-adenosine monophosphate in a Sertoli cell line.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Base Sequence; Cell Line; Colforsin; Cyclic AMP; DNA; Gene Expression; Gene Expression Regulation; Humans; Male; Mice; Molecular Sequence Data; Promoter Regions, Genetic; RNA, Messenger; Sertoli Cells; Stem Cell Factor; Testosterone; Tetradecanoylphorbol Acetate | 1996 |
Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene.
Topics: Adipose Tissue; Aromatase; Breast Neoplasms; Bucladesine; Colforsin; Cyclic AMP; Dinoprostone; Estrogens; Female; Gene Expression Regulation; Humans; Promoter Regions, Genetic; Stromal Cells; Tetradecanoylphorbol Acetate | 1996 |
Regulation of 3 beta-hydroxysteroid dehydrogenase expression in human adrenocortical H295R cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Aldosterone; Angiotensin II; Blotting, Northern; Bucladesine; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dehydroepiandrosterone; Humans; Hydrocortisone; Protein Kinase C; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Tetradecanoylphorbol Acetate | 1996 |
Regulated calcium channel in apical membranes renal proximal tubule cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium; Calcium Channels; Cations, Monovalent; Cell Membrane; Cells, Cultured; Colforsin; Epithelium; Ion Channel Gating; Kidney Tubules, Proximal; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Rabbits; Substrate Specificity; Tetradecanoylphorbol Acetate | 1996 |
Interaction between the two signal transduction systems of the histamine H2 receptor: desensitizing and sensitizing effects of histamine stimulation on histamine-dependent cAMP production in Chinese hamster ovary cells.
Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dogs; Histamine; Histamine Agonists; Indoles; Maleimides; Receptors, Histamine H2; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Signal-transduction-pathway-specific desensitization of expression of orphan nuclear receptor TIS1.
Topics: Adrenergic beta-Agonists; Animals; Colforsin; DNA-Binding Proteins; Gene Expression Regulation; Isoproterenol; Mice; Muscle, Skeletal; Nuclear Receptor Subfamily 4, Group A, Member 1; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Differential control of 17 alpha-hydroxylase and 3 beta-hydroxysteroid dehydrogenase expression in human adrenocortical H295R cells.
Topics: 3-Hydroxysteroid Dehydrogenases; Adrenal Cortex; Angiotensin II; Base Sequence; Bucladesine; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Humans; Molecular Sequence Data; Oligonucleotide Probes; Protein Kinase C; Steroid 17-alpha-Hydroxylase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Regulation of alpha 2A-adrenergic receptor mRNA in rat astroglial cultures: role of cyclic AMP and protein kinase C.
Topics: Animals; Astrocytes; Cells, Cultured; Colforsin; Cyclic AMP; Drug Stability; Gene Expression; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; RNA, Messenger; Tetradecanoylphorbol Acetate | 1997 |
Urinary trypsin inhibitor efficiently inhibits urokinase production in tumor necrosis factor-stimulated cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Blotting, Western; Bucladesine; Cell Membrane; Cells, Cultured; Colforsin; Endothelium, Vascular; Enzyme Precursors; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Glycoproteins; Humans; Protein Kinase C; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Trypsin Inhibitors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Urokinase-Type Plasminogen Activator | 1996 |
Thyroid-stimulating hormone-induced down-regulation of thyroid transcription factor 1 in rat thyroid FRTL-5 cells.
Topics: Animals; Antibody Specificity; Blotting, Northern; Bucladesine; Cell Line; Colforsin; Gene Expression Regulation; Immune Sera; Nuclear Proteins; Rats; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyroid Nuclear Factor 1; Thyrotropin; Transcription Factors | 1997 |
Pituitary adenylate cyclase-activating polypeptide (PACAP38) modulates lymphocyte and macrophage functions: stimulation of adherence and opposite effect on mobility.
Topics: Animals; Cell Adhesion; Cell Movement; Cells, Cultured; Chemotaxis, Leukocyte; Colforsin; Dose-Response Relationship, Drug; Hormone Antagonists; Lymphocytes; Macrophages, Peritoneal; Male; Neuropeptides; Neurotransmitter Agents; Peritoneal Cavity; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; Retinaldehyde; Sermorelin; Tetradecanoylphorbol Acetate; Time Factors; Vasoactive Intestinal Peptide | 1996 |
Kinetic evidence distinguishing volume-sensitive chloride current from other types in guinea-pig ventricular myocytes.
Topics: Animals; Cell Size; Chloride Channels; Colforsin; Electrophysiology; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Kinetics; Male; Membrane Potentials; Myocardium; Osmolar Concentration; Patch-Clamp Techniques; Rabbits; Tetradecanoylphorbol Acetate | 1996 |
Effect of the protein phosphatase inhibitor okadaic acid on FSH-induced granulosa cell steroidogenesis.
Topics: 1-Methyl-3-isobutylxanthine; 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Female; Follicle Stimulating Hormone; Granulosa Cells; Okadaic Acid; Phosphoprotein Phosphatases; Progesterone; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1997 |
Cloning and characterization of the 5' flanking region of the stem cell factor gene in rat Sertoli cells.
Topics: 3T3 Cells; Animals; Base Sequence; Binding Sites; Cloning, Molecular; Colforsin; Cyclic AMP; DNA-Binding Proteins; Luciferases; Male; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Recombinant Proteins; Restriction Mapping; Sequence Analysis, DNA; Sertoli Cells; Stem Cell Factor; Tetradecanoylphorbol Acetate; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic; Transfection | 1997 |
Retinoic acids differentially regulate NOR-1 and its closely related orphan nuclear receptor genes in breast cancer cell line MCF-7.
Topics: Alitretinoin; Breast Neoplasms; Colforsin; Cycloheximide; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Nerve Tissue Proteins; Nuclear Receptor Subfamily 4, Group A, Member 1; Nuclear Receptor Subfamily 4, Group A, Member 2; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Receptors, Thyroid Hormone; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 1997 |
Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic beta-cells by glucose-dependent insulinotropic polypeptide.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Membrane; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Electric Conductivity; Enzyme Inhibitors; Exocytosis; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Islets of Langerhans; Membrane Potentials; Mice; Mice, Inbred Strains; Peptide Fragments; Phosphodiesterase Inhibitors; Tetradecanoylphorbol Acetate; Thionucleotides | 1997 |
Progesterone production in vitro by mouse luteal cells: response to follicle-stimulating hormone, luteinizing hormone, and prolactin.
Topics: Animals; Bucladesine; Cells, Cultured; Colforsin; Female; Follicle Stimulating Hormone; Humans; Luteal Cells; Luteinizing Hormone; Mice; Pregnancy; Progesterone; Prolactin; Protein Kinase C; Sheep; Tetradecanoylphorbol Acetate | 1997 |
cAMP and protein kinase C elevate LH beta mRNA levels by activating transcription rather than stabilizing mRNA in rat pituitary cells.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Pituitary Gland, Anterior; Protein Kinase C; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1997 |
Adenosine stimulation of DNA synthesis in human endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Triphosphate; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA; Endothelium, Vascular; Humans; Kinetics; Poly A; Purinergic P1 Receptor Antagonists; Quinazolines; Tetradecanoylphorbol Acetate; Thioinosine; Thionucleotides; Thymidine; Triazoles; Umbilical Veins | 1997 |
Differential desensitization of thromboxane A2 receptor subtypes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Naphthalenes; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Receptors, Thromboxane; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1997 |
Increased cyclic AMP response to forskolin in Epstein-Barr virus-transformed human B-lymphocytes derived from schizophrenics.
Topics: Adult; Alprostadil; B-Lymphocytes; Cell Transformation, Viral; Cholera Toxin; Colforsin; Cyclic AMP; Female; Herpesvirus 4, Human; Humans; Isoproterenol; Lymphocyte Activation; Male; Schizophrenia; Tetradecanoylphorbol Acetate | 1997 |
The roles of adenosine 3',5'-cyclic monophosphate-dependent protein kinase A and protein kinase C in stimulus-secretion coupling in AtT-20 cells.
Topics: Adrenocorticotropic Hormone; Animals; Calcium; Cell Line; Cell Membrane Permeability; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Intercellular Signaling Peptides and Proteins; Mice; Peptides; Pituitary Gland, Anterior; Protein Kinase C; Tetradecanoylphorbol Acetate; Wasp Venoms | 1996 |
Regulation of c-fos and c-jun expression by calcitonin in human breast cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Calcitonin; Carcinogens; Cell Division; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Glycoproteins; Humans; Insulin; Isoquinolines; Metalloendopeptidases; Protein Biosynthesis; Protein Kinase Inhibitors; Proteins; Receptors, Calcitonin; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured | 1997 |
Regulation by thyroid-stimulating hormone of sodium/iodide symporter gene expression and protein levels in FRTL-5 cells.
Topics: Animals; Bucladesine; Carrier Proteins; Cell Line; CHO Cells; Colforsin; Cricetinae; Gene Expression Regulation; Iodides; Kinetics; Membrane Proteins; Rats; Recombinant Fusion Proteins; RNA, Messenger; Symporters; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Transcription, Genetic; Transfection | 1997 |
Gonadotropin-releasing hormone and pituitary adenylate cyclase-activating polypeptide affect levels of cyclic adenosine 3',5'-monophosphate-dependent protein kinase A (PKA) subunits in the clonal gonadotrope alphaT3-1 cells: evidence for cross-talk betwee
Topics: Animals; Blotting, Western; Clone Cells; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; Gonadotropin-Releasing Hormone; Kinetics; Macromolecular Substances; Neuropeptides; Neurotransmitter Agents; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland, Anterior; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1997 |
Regulation of follistatin production by rat granulosa cells in vitro.
Topics: Activins; Analysis of Variance; Animals; Cells, Cultured; Colforsin; Enzyme-Linked Immunosorbent Assay; Female; Follicle Stimulating Hormone; Follistatin; Glycoproteins; Granulosa Cells; Growth Substances; Humans; Inhibins; Kinetics; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1997 |
Involvement of different second messengers in parathyroid hormone- and interleukin-1-induced interleukin-6 and interleukin-11 production in human bone marrow stromal cells.
Topics: Bone Marrow; Bone Marrow Cells; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol; Humans; Interleukin-1; Interleukin-11; Interleukin-6; Parathyroid Hormone; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1997 |
Protein kinase C and protein kinase A inhibit calcium-dependent but not stress-dependent c-Jun N-terminal kinase activation in rat liver epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Epithelium; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; Liver; Mitogen-Activated Protein Kinases; Models, Biological; Polyenes; Protein Kinases; Rats; Recombinant Proteins; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Wortmannin | 1997 |
Activation of protein kinase C enhances the infection of endothelial cells by human cytomegalovirus.
Topics: Calcimycin; Cells, Cultured; Colforsin; Cytomegalovirus; Endothelium, Vascular; Enzyme Activation; Humans; Iloprost; Okadaic Acid; Protein Kinase C; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Umbilical Veins | 1997 |
Parathyroid hormone-related protein and human myometrial cells: action and regulation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bucladesine; Chorionic Gonadotropin; Colforsin; Corticotropin-Releasing Hormone; Female; Gene Expression Regulation; Humans; Muscle Relaxation; Myometrium; Okadaic Acid; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Pregnancy; Proteins; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1997 |
Sex hormones regulate CFTR in developing fetal rat lung epithelial cells.
Topics: Animals; Cells, Cultured; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dihydrotestosterone; Embryonic and Fetal Development; Epithelial Cells; Epithelium; Fetus; Gestational Age; Gonadal Steroid Hormones; Lung; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate | 1997 |
The regulation of prodynorphin gene expression in cultured spinal cord cells: involvement of second messengers.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Embryo, Mammalian; Enkephalins; Kinetics; Neurons; Protein Kinase C; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Second Messenger Systems; Spinal Cord; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Biglycan gene promoter activity in osteosarcoma cells is regulated by cyclic AMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Biglycan; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Indoles; Osteosarcoma; Plasmids; Promoter Regions, Genetic; Proteoglycans; Pyrroles; RNA, Messenger; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1997 |
Glucose stimulates islet beta-cell mitogenesis through GTP-binding proteins and by protein kinase C-dependent mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Atrial Natriuretic Factor; Calcium Channel Blockers; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gallopamil; Glucose; GTP-Binding Proteins; Insulin; Insulin Secretion; Ionomycin; Ionophores; Islets of Langerhans; Pertussis Toxin; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1997 |
Csa-19, a radiation-responsive human gene, identified by an unbiased two-gel cDNA library screening method in human cancer cells.
Topics: Age Factors; Blotting, Northern; Breast Neoplasms; Cloning, Molecular; Colforsin; Cyclosporine; DNA, Complementary; Dose-Response Relationship, Radiation; Down-Regulation; Gene Expression Regulation, Developmental; Gene Library; Genes, p53; HL-60 Cells; Humans; Molecular Sequence Data; Neutrons; Oncogenes; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured; X-Rays | 1997 |
Inhibition of inducible nitric oxide synthase expression by endothelin in rat glial cells prepared from the neonatal rat brain.
Topics: Animals; Animals, Newborn; Brain; Bucladesine; Colforsin; Cyclic AMP; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelins; Enzyme Induction; Interleukin-1; Neuroglia; Nitric Oxide Synthase; Nitrites; Oligopeptides; Peptide Fragments; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin B; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Expression of prostacyclin receptor in human megakaryocytes.
Topics: Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Granulocyte-Macrophage Colony-Stimulating Factor; Hematologic Neoplasms; Hematopoietic Stem Cells; HL-60 Cells; Humans; Iloprost; Interleukins; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Neoplasm Proteins; Platelet Factor 4; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Epoprostenol; Receptors, Prostaglandin; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Thrombopoietin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Melatonin-sensitive, serum-stimulated signalling in ovine pars tuberalis.
Topics: Animals; Blood; Cells, Cultured; Colforsin; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Down-Regulation; Enzyme Inhibitors; Female; Fluorescent Dyes; Fura-2; Genes, Immediate-Early; Immunoenzyme Techniques; Indoles; Male; Melatonin; Phosphorylation; Pituitary Gland, Anterior; Protein Kinase C; Proto-Oncogene Proteins c-fos; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors | 1997 |
Na-K-2Cl cotransporters are present and regulated in simian eccrine clear cells.
Topics: Amiloride; Animals; Bumetanide; Carrier Proteins; Cells, Cultured; Colforsin; Cyclic AMP; Eccrine Glands; Hand; Homeostasis; Humans; Hypertonic Solutions; Hypotonic Solutions; Isoproterenol; Macaca mulatta; Methacholine Chloride; Ouabain; Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Inhibition of protein kinase A and cyclic AMP response element (CRE)-specific transcription factor binding by delta9-tetrahydrocannabinol (delta9-THC): a putative mechanism of cannabinoid-induced immune modulation.
Topics: Animals; Antibodies, Monoclonal; CD3 Complex; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dronabinol; Enzyme Activation; Female; Hallucinogens; Ionomycin; Mice; Receptors, Cannabinoid; Receptors, Drug; Tetradecanoylphorbol Acetate | 1997 |
Spontaneous Mn2+ entry is specifically inhibited by calyculin A in human leukemic HL-60 cells.
Topics: Calcium; Colforsin; Depression, Chemical; Dimethyl Sulfoxide; Enzyme Inhibitors; HL-60 Cells; Humans; Manganese; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate | 1997 |
Activation of phospholipase D in FRTL-5 thyroid cells by forskolin and dibutyryl-cyclic adenosine monophosphate.
Topics: Alkaloids; Animals; Benzophenanthridines; Bucladesine; Calcium; Cell Line; Colforsin; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Glycerophospholipids; Humans; Naphthalenes; Phenanthridines; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1997 |
Ammonia effect on calcium-activated chloride secretion in T84 intestinal epithelial monolayers.
Topics: Ammonia; Barium; Calcimycin; Calcium; Carbachol; Cell Line; Chlorides; Colforsin; Cyclic AMP; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Intestinal Mucosa; Intracellular Membranes; Ionomycin; Ionophores; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Opposite regulation of adenylyl cyclase by protein kinase C in astrocyte and microglia cultures.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Astrocytes; Cell Membrane; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Cytosol; Enzyme Inhibitors; Homeostasis; Isoproterenol; Kinetics; Microglia; Naphthalenes; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Stimulation of brook trout ovarian steroidogenesis by gonadotropins I and II is mediated by the cyclic adenosine 3',5'-monophosphate/protein kinase A pathway.
Topics: Animals; Calcimycin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol; Female; Gonadotropins, Pituitary; Hydroxyprogesterones; Ionophores; Naphthalenes; Ovarian Follicle; Ovary; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Trout | 1997 |
Complex shape changes in isolated rat osteoclasts: involvement of protein kinase C in the response to calcitonin.
Topics: Analgesics; Animals; Calcitonin; Carcinogens; Cell Separation; Cell Size; Colforsin; Cyclic AMP; Cytoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Naphthalenes; Osteoclasts; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1997 |
Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GTP-Binding Proteins; Indoles; Isomerism; Isoproterenol; Kinetics; Liver; Male; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Signal Transduction; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetradecanoylphorbol Acetate | 1997 |
Hormonal regulation of monocyte chemoattractant protein-1 messenger ribonucleic acid expression in corpora lutea.
Topics: Animals; Base Sequence; Cattle; Chemokine CCL2; Colforsin; Corpus Luteum; Cyclic AMP-Dependent Protein Kinases; Dinoprost; DNA; DNA Primers; Dose-Response Relationship, Drug; Enzyme Activation; Female; Linear Models; Luteinizing Hormone; Luteolysis; Ovulation; Polymerase Chain Reaction; Prolactin; Protein Kinase C; RNA, Messenger; Sheep; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Parathyroid hormone (1-34)-mediated interleukin-6 induction.
Topics: Becaplermin; Calcimycin; Colforsin; Dinoprostone; Drug Interactions; Gene Expression; Humans; Interleukin-1; Interleukin-6; Osteosarcoma; Plasmids; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Proto-Oncogene Proteins c-sis; Recombinant Fusion Proteins; Teriparatide; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1997 |
Keratinocyte growth factor expression in the mesenchymal cells of human amnion.
Topics: Amnion; Blood Physiological Phenomena; Cell Division; Cells, Cultured; Colforsin; Dexamethasone; Epithelial Cells; Female; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Glucocorticoids; Growth Substances; Humans; Mesoderm; Pregnancy; RNA, Messenger; Tetradecanoylphorbol Acetate | 1997 |
Mechanisms of action of growth hormone-releasing peptide-2 in bovine pituitary cells.
Topics: Animals; Calcium Channel Blockers; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activation; Growth Hormone; Growth Hormone-Releasing Hormone; Hormones; Male; Nifedipine; Oligopeptides; Pituitary Gland, Anterior; Protein Kinase C; Somatostatin; Tetradecanoylphorbol Acetate | 1997 |
Phosphorylation of the human calcitonin receptor by multiple kinases is localized to the C-terminus.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calcitonin; Cells, Cultured; Colforsin; Cricetinae; Cyanogen Bromide; Electrophoresis, Polyacrylamide Gel; Humans; Kidney; Molecular Sequence Data; Phosphorus Radioisotopes; Phosphorylation; Precipitin Tests; Receptors, Calcitonin; Tetradecanoylphorbol Acetate; Transfection | 1997 |
Effect of phorbol ester on the regulation of LH/hCG receptors.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colforsin; Enzyme Activation; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Protein Kinase C; Rats; Rats, Wistar; Receptors, LH; RNA, Messenger; Tetradecanoylphorbol Acetate | 1997 |
Differential effects of basic fibroblast growth factor, epidermal growth factor, transforming growth factor-alpha, and insulin-like growth factor-I on a hypothalamic gonadotropin-releasing hormone neuronal cell line.
Topics: Animals; Carcinogens; Cell Count; Cell Division; Cell Line, Transformed; Colforsin; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression; Gonadotropin-Releasing Hormone; Gonadotropins; Growth Substances; Hypothalamus; Insulin-Like Growth Factor I; Mice; Neurites; Neurons; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymidine; Transforming Growth Factor alpha; Transgenes; Tritium | 1997 |
Molecular characterization and differential gene induction of the neuroendocrine-specific genes neurotensin, neurotensin receptor, PC1, PC2, and 7B2 in the human ocular ciliary epithelium.
Topics: Aspartic Acid Endopeptidases; Cell Line; Ciliary Body; Colforsin; Dexamethasone; DNA Primers; Enzyme Induction; Epithelial Cells; Furin; Gene Expression Regulation; Humans; Isoproterenol; Models, Biological; Nerve Growth Factors; Neurosecretory Systems; Neurotensin; Polymerase Chain Reaction; Proprotein Convertase 2; Proprotein Convertases; Receptors, Neurotensin; Subtilisins; Tetradecanoylphorbol Acetate; Timolol; Transcriptional Activation; Up-Regulation | 1997 |
Inhibitory effect of 2-phenyl-4-quinolone on serotonin-mediated changes in the morphology and permeability of endothelial monolayers.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Biological Transport; Cattle; Cell Size; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic GMP; Endothelium; Enzyme Inhibitors; Gap Junctions; Myocardium; Nitroprusside; Permeability; Protein Kinase C; Quinolones; Rats; Serotonin; Serum Albumin; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Regulation of endothelin-1 gene expression by cell shape and the microfilament network in vascular endothelium.
Topics: Actin Cytoskeleton; Actins; Animals; Aorta; Cattle; Cell Size; Cells, Cultured; Colforsin; Cytochalasin D; Cytoskeleton; Endothelin-1; Endothelium, Vascular; Gene Expression Regulation; Genistein; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Modulatory effects of PKC activity on increased 92-kDa gelatinase secretion by neonatal alveolar macrophages.
Topics: Aging; Animals; Animals, Newborn; Bucladesine; Cell Membrane; Cells, Cultured; Colforsin; Concanavalin A; Cyclic AMP; Cysteine Endopeptidases; Enzyme Inhibitors; Gelatinases; Gene Expression Regulation, Enzymologic; Kinetics; Macrophages, Alveolar; Molecular Weight; Naphthalenes; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of PAH transport by parathyroid hormone in OK cells: involvement of protein kinase C pathway.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Bucladesine; Cell Line; Cell Membrane; Colforsin; Kidney; Kinetics; Mannitol; p-Aminohippuric Acid; Protein Kinase C; Second Messenger Systems; Staurosporine; Teriparatide; Tetradecanoylphorbol Acetate | 1997 |
Estrogens stimulate tamoxifen-induced neuronal cell apoptosis in vitro: a possible nongenomic action.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Colforsin; DNA Fragmentation; Estradiol; Estriol; Estrogens; Ethinyl Estradiol; Hypothalamus; Kinetics; Luciferases; Nerve Growth Factors; Neurons; Polymerase Chain Reaction; Quinestrol; Receptors, Estrogen; Recombinant Fusion Proteins; Tamoxifen; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Xenopus | 1997 |
Opposite effects of astrocyte-derived soluble factor(s) on the functional expression of fetal peptidergic neurons in aggregate cultures: enhancement of neuropeptide Y and suppression of somatostatin.
Topics: Animals; Astrocytes; Biological Factors; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Colforsin; Embryonic and Fetal Development; Female; Humans; Neurons; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Solubility; Somatostatin; Species Specificity; Tetradecanoylphorbol Acetate | 1997 |
Effects of protein kinase modulators on the sodium pump activities of HeLa cells transfected with distinct alpha isoforms of Na,K-ATPase.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; HeLa Cells; Humans; Isoenzymes; Kinetics; Ouabain; Protein Kinase C; Rats; Recombinant Proteins; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Transfection | 1997 |
cAMP involvement in the expression of MMP-2 and MT-MMP1 metalloproteinases in human endothelial cells.
Topics: Bucladesine; Cells, Cultured; Colforsin; Collagenases; Culture Media, Conditioned; Culture Media, Serum-Free; Cyclic AMP; Endothelium, Vascular; Enzyme Induction; Gelatinases; Humans; Isoenzymes; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Membrane Proteins; Metalloendopeptidases; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Umbilical Veins | 1997 |
Regulation of alpha2A-adrenergic receptor expression by epinephrine in cultured astroglia from rat brain.
Topics: Animals; Astrocytes; Brain; Cells, Cultured; Colforsin; Epinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; RNA, Messenger; Tetradecanoylphorbol Acetate | 1998 |
Cloning and structural organization of the gene encoding the mouse glial cell line-derived neurotrophic factor, GDNF.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Colforsin; Exons; Gene Expression Regulation; Gene Library; Glial Cell Line-Derived Neurotrophic Factor; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Nerve Growth Factors; Nerve Tissue Proteins; Precipitin Tests; Protein Biosynthesis; RNA, Messenger; Sequence Analysis, DNA; TATA Box; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Sodium, potassium, two chloride cotransport in corneal endothelium: characterization and possible role in volume regulation and fluid transport.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Bumetanide; Carrier Proteins; Cattle; Cell Size; Cells, Cultured; Chlorides; Colforsin; Dose-Response Relationship, Drug; Endothelium, Corneal; Enzyme Inhibitors; Membrane Proteins; Ouabain; Potassium; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate | 1998 |
Activation of the human histamine H2 receptor is linked to cell proliferation and c-fos gene transcription.
Topics: Cell Division; Cell Line; Cimetidine; Cloning, Molecular; Colforsin; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; Epinephrine; Genes, fos; Genes, Reporter; Histamine; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; Luciferases; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-fos; Receptors, Histamine H2; Recombinant Fusion Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1997 |
ACTH-induced cortisol secretion is mediated by cAMP and PKC in various adrenocortical adenomas.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin II; Colforsin; Cushing Syndrome; Cyclic AMP; Cytosol; Female; Humans; Hydrocortisone; Immunoblotting; Male; Membrane Proteins; Middle Aged; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1997 |
Adrenergic-mediated connexin43 phosphorylation in the ocular ciliary epithelium.
Topics: Adrenergic beta-Agonists; Animals; Antibodies, Monoclonal; Blotting, Western; Ciliary Body; Colforsin; Connexin 43; Cyclic AMP; Epithelial Cells; Fluorescent Antibody Technique, Indirect; Isoproterenol; Phosphorylation; Pigment Epithelium of Eye; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1998 |
NGF, cyclic AMP, and phorbol esters regulate oxytocin receptor gene transcription in SK-N-SH and MCF7 cells.
Topics: Animals; Brain; Breast Neoplasms; Cloning, Molecular; Colforsin; Cyclic AMP; DNA-Binding Proteins; Female; Humans; Nerve Growth Factors; Neuroblastoma; Promoter Regions, Genetic; Rats; Receptors, Oxytocin; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
Structure and regulation of the human growth hormone-releasing hormone receptor gene.
Topics: Base Sequence; Cloning, Molecular; Colforsin; DNA-Binding Proteins; Estrogens; Gene Expression Regulation; Glucocorticoids; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Neuropeptide; Receptors, Pituitary Hormone-Regulating Hormone; Sequence Analysis, DNA; Tetradecanoylphorbol Acetate; Transcription Factor Pit-1; Transcription Factors; Transcription, Genetic | 1998 |
Characterization and regulation of adenosine transport in T84 intestinal epithelial cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Biological Transport; Carrier Proteins; Cells, Cultured; Colforsin; Down-Regulation; Humans; Intestinal Mucosa; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Sodium; Tetradecanoylphorbol Acetate; Thioinosine; Vasodilator Agents | 1998 |
Functional characterization of the murine serotonin transporter gene promoter in serotonergic raphe neurons.
Topics: Animals; Base Sequence; Carcinogens; Carrier Proteins; Cerebral Cortex; Choriocarcinoma; Colforsin; Cyclic AMP; Female; Fetus; Gene Deletion; Gene Expression Regulation, Developmental; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Molecular Sequence Data; Mutagenesis; Nerve Tissue Proteins; Neurons; Phosphopyruvate Hydratase; Pregnancy; Protein Kinase C; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Plasma Membrane Transport Proteins; TATA Box; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Nutrient augmentation of Ca2+-dependent and Ca2+-independent pathways in stimulus-coupling to insulin secretion can be distinguished by their guanosine triphosphate requirements: studies on rat pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Calcium; Colforsin; Glucose; Guanosine Triphosphate; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mycophenolic Acid; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Triiodothyronine modulates interleukin-6 synthesis in osteoblasts: inhibitions in protein kinase A and C pathways.
Topics: Alprostadil; Animals; Bucladesine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Interleukin-1; Interleukin-6; Mice; Osteoblasts; Protein Kinase C; Tetradecanoylphorbol Acetate; Triiodothyronine | 1998 |
The effects of treatment with chemical agents or infection with feline viruses on protein-binding properties of the feline immunodeficiency virus long terminal repeat.
Topics: Animals; Binding Sites; Cats; Cell Line; Colforsin; Herpesviridae; Immunodeficiency Virus, Feline; Nuclear Proteins; Peptide Chain Initiation, Translational; Repetitive Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1997 |
Synergistic activation of RLD-1 by agents triggering PKA and PKC dependent signalling.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; CHO Cells; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; DNA-Binding Proteins; Drug Synergism; Enzyme Inhibitors; Genes, Reporter; Hydroxycholesterols; Indoles; Isoquinolines; Liver X Receptors; Maleimides; Orphan Nuclear Receptors; Protein Kinase C; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 1998 |
A role for protein kinase C alpha in stimulation of prostaglandin G/H synthase-2 transcription by 14,15-epoxyeicosatrienoic acid.
Topics: 16,16-Dimethylprostaglandin E2; 8,11,14-Eicosatrienoic Acid; Animals; Cell Line; Colforsin; Cyclooxygenase 2; Diclofenac; Epithelial Cells; Intestinal Mucosa; Isoenzymes; Ketoconazole; Metyrapone; Miconazole; Peroxidases; Prostaglandin-Endoperoxide Synthases; Prostaglandins F, Synthetic; Protein Kinase C; Protein Kinase C-alpha; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1998 |
Effects of leptin on insulin secretion from isolated rat pancreatic islets.
Topics: Animals; Calcium; Colforsin; Enzyme Activation; Glucose; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Leptin; Male; Mice; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Palmitate and myristate selectively mimic the effect of glucose in augmenting insulin release in the absence of extracellular Ca2+.
Topics: Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Malonyl Coenzyme A; Myristic Acid; Osmolar Concentration; Palmitates; Perfusion; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Glucagon-like-peptide-1 secretion from canine L-cells is increased by glucose-dependent-insulinotropic peptide but unaffected by glucose.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dogs; Enteroendocrine Cells; Enzyme Activation; Enzyme Inhibitors; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucose; Immunohistochemistry; Isoquinolines; Male; Peptide Fragments; Protein Kinase C; Protein Precursors; Somatostatin; Tetradecanoylphorbol Acetate | 1998 |
Metabolism of phosphatidylcholine in mouse pancreatic islets.
Topics: Adenosine Triphosphate; Aluminum Chloride; Aluminum Compounds; Animals; Calcimycin; Cells, Cultured; Chlorides; Choline; Colforsin; Glucose; Islets of Langerhans; Kinetics; Male; Mice; Mice, Inbred Strains; Phosphatidylcholines; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Colforsin; Cyclic AMP; Enzyme Inhibitors; Flavonoids; Luciferases; Melanoma, Experimental; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Monophenol Monooxygenase; Protein Kinase Inhibitors; Protein Kinases; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Na+ -phosphate cotransport in mouse distal convoluted tubule cells: evidence for Glvr-1 and Ram-1 gene expression.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cells, Cultured; Colforsin; Gene Expression; Hydrogen-Ion Concentration; Kidney Tubules, Distal; Kidney Tubules, Proximal; Mice; Oligonucleotides, Antisense; Parathyroid Hormone; Phosphate Transport Proteins; Polymerase Chain Reaction; Receptors, Virus; RNA; Sodium-Phosphate Cotransporter Proteins; Sodium-Phosphate Cotransporter Proteins, Type I; Sodium-Phosphate Cotransporter Proteins, Type III; Symporters; Tetradecanoylphorbol Acetate | 1998 |
Alanine-261 in intracellular loop III of the human gonadotropin-releasing hormone receptor is crucial for G-protein coupling and receptor internalization.
Topics: Alanine; Animals; Binding Sites; Binding, Competitive; Colforsin; COS Cells; Endocytosis; Gonadotropin-Releasing Hormone; GTP-Binding Proteins; Humans; Inositol Phosphates; Ligands; Mutagenesis, Site-Directed; Protein Binding; Receptors, LHRH; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Enhanced NOR-1 gene expression by exposure of Chinese hamster cells to high-density 50 Hz magnetic fields.
Topics: Animals; Calcium Channel Blockers; Carotenoids; CHO Cells; Colforsin; Cricetinae; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation; Magnetics; Naphthalenes; Nerve Tissue Proteins; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Vitamin A | 1998 |
Multiple intracellular pathways interfere with the activation of a CPP32-like protease induced by serum deprivation of AKR-2B cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Becaplermin; Carcinogens; Caspase 3; Caspases; Cell Death; Cell Survival; Cells, Cultured; Colchicine; Colforsin; Coumarins; Culture Media, Serum-Free; Cyclic AMP; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Precursors; Fibroblasts; Fluorescent Dyes; Mice; Mice, Inbred AKR; Oligopeptides; Platelet-Derived Growth Factor; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-sis; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Signaling pathways mediating induction of the early response genes prostaglandin G/H synthase-2 and egr-1 by serotonin via 5-HT2A receptors.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclooxygenase 2; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Genes, Immediate-Early; Glomerular Mesangium; Immediate-Early Proteins; Isoenzymes; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation | 1998 |
Cloning and characterization of the mouse pituitary adenylate cyclase-activating polypeptide (PACAP) gene.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Colforsin; Gene Expression Regulation, Enzymologic; Genes, Reporter; Mice; Molecular Sequence Data; Neuropeptides; PC12 Cells; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Promoter Regions, Genetic; Rats; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1998 |
Effect of vitamin D3 on interleukin-6 synthesis induced by prostaglandins in osteoblasts.
Topics: Alprostadil; Animals; Bucladesine; Calcitriol; Carcinogens; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Dose-Response Relationship, Drug; Interleukin-6; Mice; Osteoblasts; Tetradecanoylphorbol Acetate | 1998 |
Cyclic adenosine monophosphate inhibits nitric oxide-induced apoptosis in human leukemic HL-60 cells.
Topics: Apoptosis; Bucladesine; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dimethyl Sulfoxide; Glutathione; HL-60 Cells; Humans; Nitric Oxide; Nitroprusside; Nitroso Compounds; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1998 |
In B16 melanoma cells, the inhibition of melanogenesis by TPA results from PKC activation and diminution of microphthalmia binding to the M-box of the tyrosinase promoter.
Topics: Animals; Binding Sites; Carcinogens; Colforsin; DNA-Binding Proteins; Enzyme Activation; Helix-Loop-Helix Motifs; Isoenzymes; Melanoma, Experimental; Mice; Microphthalmia-Associated Transcription Factor; Monophenol Monooxygenase; Promoter Regions, Genetic; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation | 1998 |
Activity-dependent regulation of [Ca2+]i in avian cochlear nucleus neurons: roles of protein kinases A and C and relation to cell death.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Apoptosis; Autonomic Denervation; Brain Stem; Calcium; Chick Embryo; Cochlear Nucleus; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Enzyme Activation; Estrenes; Homeostasis; Indoles; Ion Transport; Maleimides; Nerve Tissue Proteins; Protein Kinase C; Pyrrolidinones; Receptors, Metabotropic Glutamate; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides | 1998 |
Protein kinase A, protein kinase C, and Ca(2+)-regulated expression of 21-hydroxylase cytochrome P450 in H295R human adrenocortical cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Cortex; Angiotensin II; Bucladesine; Calcium; Calcium Channel Agonists; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; Humans; Potassium; Protein Kinase C; RNA, Messenger; Signal Transduction; Steroid 21-Hydroxylase; Tetradecanoylphorbol Acetate | 1998 |
Retinoic acid suppresses interleukin-6 synthesis induced by prostaglandins in osteoblasts.
Topics: Alprostadil; Animals; Bucladesine; Carcinogens; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Dose-Response Relationship, Drug; Fibrinolytic Agents; Interleukin-1; Interleukin-6; Keratolytic Agents; Osteoblasts; Oxytocics; Prostaglandins; Tetradecanoylphorbol Acetate; Tretinoin | 1998 |
Galanin inhibits glucagon-like peptide-1 secretion through pertussis toxin-sensitive G protein and ATP-dependent potassium channels in rat ileal L-cells.
Topics: Animals; Bombesin; Cells, Cultured; Colforsin; Disopyramide; Dose-Response Relationship, Drug; Galanin; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; GTP-Binding Proteins; Ileum; Immunohistochemistry; Male; Microscopy, Fluorescence; Peptide Fragments; Pertussis Toxin; Potassium Channels; Protein Precursors; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
Regulation of 11beta-hydroxysteroid dehydrogenase type 2 by progesterone, estrogen, and the cyclic adenosine 5'-monophosphate pathway in cultured human placental and chorionic trophoblasts.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Cells, Cultured; Chorion; Colforsin; Cyclic AMP; Estradiol; Female; Gene Expression Regulation; Humans; Hydroxysteroid Dehydrogenases; Placenta; Pregnancy; Progesterone; RNA, Messenger; Tetradecanoylphorbol Acetate; Trophoblasts | 1998 |
P2X receptors in cochlear Deiters' cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cochlea; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Patch-Clamp Techniques; Protein Kinases; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Tetradecanoylphorbol Acetate; Thionucleotides; Uridine Triphosphate; Vasodilator Agents; Vestibular Nucleus, Lateral | 1998 |
Glucose augmentation of mastoparan-stimulated insulin secretion in rat and human pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Calcium; Colforsin; Glucose; Guanosine Triphosphate; Humans; Insulin; Insulin Secretion; Intercellular Signaling Peptides and Proteins; Islets of Langerhans; Keto Acids; Male; Mannoheptulose; Organ Culture Techniques; Peptides; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Wasp Venoms | 1998 |
Regulation of prostaglandin G/H synthase-2 expression by interleukin-1 in human osteoblast-like cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line, Transformed; Colforsin; Cycloheximide; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Interleukin-1; Isoenzymes; Membrane Proteins; Osteoblasts; Osteosarcoma; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Synthesis Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
The cyclosporin A-sensitive nuclear factor of activated T cells (NFAT) proteins are expressed in vascular smooth muscle cells. Differential localization of NFAT isoforms and induction of NFAT-mediated transcription by phospholipase C-coupled cell surface
Topics: Angiotensin II; Animals; Becaplermin; Calcium; Cells, Cultured; Colforsin; Cyclosporine; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; GTP-Binding Proteins; Immunohistochemistry; Muscle, Smooth, Vascular; NFATC Transcription Factors; Nuclear Proteins; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thrombin; Transcription Factors; Type C Phospholipases | 1998 |
Transcriptional regulation of fibroblast growth factor-2 expression in human astrocytes: implications for cell plasticity.
Topics: Astrocytes; Base Sequence; Binding Sites; Brain; Cell Nucleus; Cells, Cultured; Colforsin; DNA-Binding Proteins; Epidermal Growth Factor; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Interleukin-1; Luciferases; Mitosis; Molecular Sequence Data; Neuronal Plasticity; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Polymerase Chain Reaction; Promoter Regions, Genetic; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1998 |
Riboflavin uptake by the human-derived liver cells Hep G2: mechanism and regulation.
Topics: Antiemetics; Biological Transport; Bucladesine; Calcium; Calmodulin; Carcinogens; Carcinoma, Hepatocellular; Carrier Proteins; Cholera Toxin; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Flavins; Genistein; Humans; Imidazoles; Protein Kinase C; Riboflavin; Signal Transduction; Tetradecanoylphorbol Acetate; Trifluoperazine; Tritium; Tumor Cells, Cultured; Vanadates | 1998 |
Parathyroid hormone responses of cyclic AMP-, serum- and phorbol ester-responsive reporter genes in osteoblast-like UMR-106 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Base Sequence; Blood; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Gene Expression Regulation; Genes, Reporter; Luciferases; Mitogen-Activated Protein Kinase 1; Molecular Sequence Data; Osteoblasts; Parathyroid Hormone; Rats; Regulatory Sequences, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Sphingosine modulates interleukin-6 synthesis in osteoblasts.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Immunoenzyme Techniques; Interleukin-1; Interleukin-6; Mice; Osteoblasts; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
The pro-protein convertase PC1 is induced in the transected sciatic nerve and is present in cultured Schwann cells: comparison with PC5, furin and PC7, implication in pro-BDNF processing.
Topics: Animals; Aspartic Acid Endopeptidases; Biomarkers; Blotting, Northern; Brain-Derived Neurotrophic Factor; Carcinogens; Cells, Cultured; Colforsin; Denervation; Furin; Gene Expression Regulation, Enzymologic; In Situ Hybridization; Ionomycin; Ionophores; Male; Nerve Growth Factors; Proprotein Convertase 1; Proprotein Convertase 5; Proprotein Convertases; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Schwann Cells; Sciatic Nerve; Serine Endopeptidases; Subtilisins; Tetradecanoylphorbol Acetate; Vaccinia | 1998 |
Prostaglandin F2alpha stimulates CFTR activity by PKA- and PKC-dependent phosphorylation.
Topics: 3T3 Cells; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprost; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Iodides; Isoquinolines; Kinetics; Mice; Phosphopeptides; Phosphorylation; Protein Kinase C; Recombinant Proteins; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Molecular mechanism(s) of action of norepinephrine on the expression of the angiotensinogen gene in opossum kidney cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensinogen; Animals; Colforsin; Estrenes; Isoproterenol; Kidney; Norepinephrine; Opossums; Pyrrolidinones; Tetradecanoylphorbol Acetate | 1998 |
Altered regulation of bladder nerve growth factor and neurally mediated hyperactive voiding.
Topics: Animals; Cells, Cultured; Colforsin; Hypertension; Isoproterenol; Nerve Growth Factors; Neuronal Plasticity; Neuropeptide Y; Phenylephrine; Platelet-Derived Growth Factor; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Tetradecanoylphorbol Acetate; Urinary Bladder; Urination; Urination Disorders | 1998 |
Prostaglandin E2 stimulates IL-8 gene expression in human colonic epithelial cells by a posttranscriptional mechanism.
Topics: Adenocarcinoma; Bucladesine; Colforsin; Colon; Colonic Neoplasms; Cyclic AMP; Dexamethasone; Dinoprostone; Dose-Response Relationship, Immunologic; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Interleukin-8; Intracellular Fluid; Neoplasm Proteins; Protein Processing, Post-Translational; Receptors, Prostaglandin E; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Parathyroid hormone induces interleukin-6 heterogeneous nuclear and messenger RNA expression in murine calvarial organ cultures.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Cell Nucleus; Colforsin; DNA Primers; Interleukin-6; Ionomycin; Mice; Organ Culture Techniques; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Heterogeneous Nuclear; RNA, Messenger; Signal Transduction; Skull; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1998 |
Adenylate cyclases in keratinocytes: FRSK cells express types I, II, III, IV, VI and VIII, and 1,25(OH)2D3, retinoic acid and TPA augment forskolin-induced cyclic AMP accumulation in the absence of altered isozyme expression.
Topics: Adenylyl Cyclases; Animals; Calcitriol; Carcinogens; Cell Line; Colforsin; Cyclic AMP; Dermatologic Agents; Gene Expression Regulation, Enzymologic; Isoenzymes; Keratinocytes; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin | 1998 |
Regulation of tyrosine hydroxylase gene expression during transdifferentiation of striatal neurons: changes in transcription factors binding the AP-1 site.
Topics: 1-Methyl-3-isobutylxanthine; Activating Transcription Factor 2; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Differentiation; Chamomile; Colforsin; Corpus Striatum; Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Dopamine; Enzyme Inhibitors; Female; Fibroblast Growth Factor 1; Flavonoids; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Neurons; Oils, Volatile; Phosphodiesterase Inhibitors; Plants, Medicinal; Pregnancy; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Repressor Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Tyrosine 3-Monooxygenase | 1998 |
Secretory mechanisms of growth hormone (GH)-releasing peptide-, GH-releasing hormone-, and thyrotropin-releasing hormone-induced GH release in patients with acromegaly.
Topics: Acromegaly; Adenoma; Adult; Colforsin; Drug Combinations; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Male; Masoprocol; Middle Aged; Oligopeptides; Pituitary Neoplasms; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1998 |
Augmentation of leptin synthesis and secretion through activation of protein kinases A and C in cultured human trophoblastic cells.
Topics: Cell Line; Chorion; Chromatography; Colforsin; Culture Media; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Humans; Leptin; Osmolar Concentration; Placenta; Pregnancy; Protein Kinase C; Proteins; Radioimmunoassay; RNA, Messenger; Tetradecanoylphorbol Acetate; Trophoblasts | 1998 |
Chronic oxytocin pretreatment inhibits adenylyl cyclase activity in cultured rat myometrial cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Animals; Cells, Cultured; Chlorides; Colforsin; Enzyme Inhibitors; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Isoproterenol; Manganese Compounds; Myometrium; Oxytocin; Pertussis Toxin; Phenylephrine; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sodium Fluoride; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1998 |
Opposing effects of protein kinase A and C on capacitative calcium entry into HL-60 promyelocytes.
Topics: Calcium; Calcium-Transporting ATPases; Cell Differentiation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Granulocytes; HL-60 Cells; Humans; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Dopamine agonist treatment ameliorates hyperglycemia, hyperlipidemia, and the elevated basal insulin release from islets of ob/ob mice.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Blood Glucose; Bromocriptine; Colforsin; Cyclic AMP; Dopamine Agonists; Glucokinase; Glucose; Hexokinase; Hyperglycemia; Hyperlipidemias; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lipids; Mice; Mice, Inbred C57BL; Mice, Obese; Protein Kinase C; Tetradecanoylphorbol Acetate | 1998 |
Parallel modulation of striatal dopamine synthetic enzymes by second messenger pathways.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Carcinogens; Colforsin; Dopamine; Dopamine Agents; Injections, Intraventricular; Male; Mesencephalon; Mice; MPTP Poisoning; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1998 |
Regulation of plasminogen activator inhibitor-1 mRNA accumulation by basic fibroblast growth factor and transforming growth factor-beta1 in cultured rat astrocytes.
Topics: Animals; Astrocytes; Cell Count; Cells, Cultured; Colforsin; Cycloheximide; Dactinomycin; Fibroblast Growth Factor 2; Nucleic Acid Synthesis Inhibitors; Plasminogen Activator Inhibitor 1; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1998 |
Expression, functional characterization and tissue distribution of a Na+/H+ exchanger cloned from Xenopus laevis oocytes (XL-NHE).
Topics: Amiloride; Animals; Cell Line; Cloning, Molecular; Colforsin; Cricetinae; Female; Fibroblasts; Gene Expression; Hydrogen-Ion Concentration; Kinetics; Lung; Oocytes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Transfection; Xenopus laevis | 1998 |
Evidence for regulated expression of neuropeptide Y gene by rat and human cultured astrocytes.
Topics: Animals; Astrocytes; Brain-Derived Neurotrophic Factor; Cells, Cultured; Colforsin; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Immunohistochemistry; Neocortex; Neuropeptide Y; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, Nerve Growth Factor; Receptors, Neurokinin-1; RNA, Messenger; Substance P; Tetradecanoylphorbol Acetate | 1998 |
Antisense oligonucleotide to PKC-epsilon alters cAMP-dependent stimulation of CFTR in Calu-3 cells.
Topics: Animals; Base Sequence; Cell Line; Chlorides; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Epinephrine; Gene Expression Regulation, Enzymologic; Isoenzymes; Mice; Oligodeoxyribonucleotides, Antisense; Protein Kinase C; Protein Kinase C-epsilon; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection | 1998 |
Supramaximal CCK and CCh concentrations abolish VIP potentiation by inhibiting adenylyl cyclase activity.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Amylases; Animals; Bombesin; Carbachol; Cell Membrane; Cholecystokinin; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; In Vitro Techniques; Kinetics; Male; Pancreas; Pilocarpine; Rats; Rats, Wistar; Sincalide; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1998 |
Stage-specific nuclear expression of NF-kappaB in mammalian testis.
Topics: Animals; Cell Nucleus; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Induction; Follicle Stimulating Hormone; Gene Expression Regulation, Developmental; Genes, Reporter; Male; Molecular Weight; NF-kappa B; Protein Isoforms; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Sertoli Cells; Testis; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 1998 |
PACAP activates calcium influx-dependent and -independent pathways to couple met-enkephalin secretion and biosynthesis in chromaffin cells.
Topics: Adrenal Glands; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Cattle; Chromaffin Cells; Colforsin; Cyclic AMP; Enkephalin, Methionine; Enkephalins; Gene Expression Regulation; Male; Models, Biological; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium; Protein Precursors; Radioimmunoassay; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1998 |
Insulin-like growth factor binding proteins localize to discrete cell culture compartments in periosteal and osteoblast cultures from fetal rat bone.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Membrane; Cells, Cultured; Colforsin; Culture Media, Conditioned; Cyclic AMP-Dependent Protein Kinases; Glycosylation; Insulin-Like Growth Factor Binding Proteins; Molecular Weight; Osteoblasts; Parietal Bone; Periosteum; Prostaglandins; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1998 |
Molecular identification and coexpression of galanin and GalR-1 galanin receptor in the human ocular ciliary epithelium: differential modulation of their expression by the activation of alpha2- and beta2-adrenergic receptors in cultured ciliary epithelial
Topics: Adrenergic alpha-Agonists; Aqueous Humor; Cell Line; Ciliary Body; Clonidine; Colforsin; Culture Media, Serum-Free; Epithelial Cells; Fluorescent Antibody Technique; Galanin; Humans; Norepinephrine; Protein Precursors; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Galanin; Receptors, Neuropeptide; RNA, Messenger; Tetradecanoylphorbol Acetate | 1998 |
A potential role of Ras-mediated signal transduction for the enhancement of depolarization-induced Ca2+ responses in hippocampal neurons by basic fibroblast growth factor.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androstadienes; Animals; Antimanic Agents; Calcium; Calcium Channels; Calcium Channels, N-Type; Carcinogens; Cells, Cultured; Colforsin; Cyclic AMP; Electrophysiology; Enzyme Inhibitors; Estrenes; Fibroblast Growth Factor 2; Hippocampus; Lithium Chloride; Membrane Potentials; Naphthalenes; Neurons; Phosphodiesterase Inhibitors; Protein Kinase C; Proto-Oncogene Proteins c-raf; Pyrrolidinones; ras Proteins; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 1998 |
Regulation of human renin gene promoter activity: a new negative regulatory region determines the responsiveness to TNF alpha.
Topics: Adrenal Glands; Angiotensin II; Animals; Calcimycin; Cell Line; Colforsin; Cytokines; DNA; Haplorhini; Humans; Ionophores; Mice; Promoter Regions, Genetic; Renin; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 1998 |
Identification of a functional 3',5'-cyclic adenosine monophosphate response element within the second promoter of the mouse somatostatin receptor type 2 gene.
Topics: Animals; Base Sequence; Binding, Competitive; Cell Line; Colforsin; Consensus Sequence; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; DNA; Gene Expression Regulation; Genes, Reporter; Mice; Nuclear Proteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Receptors, Somatostatin; Response Elements; Sequence Deletion; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Hormonal regulation of 18S RNA, leptin mRNA, and leptin release in adipocytes from hypothyroid rats.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Colforsin; Dexamethasone; Dioxoles; Epidermal Growth Factor; Glyceraldehyde-3-Phosphate Dehydrogenases; Hypothyroidism; Insulin; Leptin; Male; Oxytocin; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Ribosomal, 18S; Tetradecanoylphorbol Acetate | 1998 |
Identification of two regions in the cytoplasmic domain of CD44 through which PMA, calcium, and foskolin differentially regulate the binding of CD44 to hyaluronic acid.
Topics: Arginine; Binding Sites; Calcium; Colforsin; Cytoplasm; Dimerization; Humans; Hyaluronan Receptors; Hyaluronic Acid; Intracellular Fluid; Jurkat Cells; Lysine; Mitogens; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Regulatory mechanism of pepsinogen gene expression in monolayer cultured guinea pig gastric chief cells.
Topics: Animals; Carbachol; Cells, Cultured; Chief Cells, Gastric; Colforsin; Cyclic AMP; Electrophoresis, Capillary; Gene Expression Regulation; Guinea Pigs; Ionomycin; Male; Pepsinogens; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Up-Regulation | 1998 |
Coordinate and divergent regulation of corticotropin-releasing factor (CRF) and CRF-binding protein expression in an immortalized amygdalar neuronal cell line.
Topics: Amygdala; Animals; Carrier Proteins; Cell Line, Transformed; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Gene Expression Regulation; Immunohistochemistry; Interleukin-6; Neurons; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Regulation of natriuretic peptide (urodilatin) release in a human kidney cell line.
Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Calcimycin; Cell Line; Colforsin; Culture Media; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Intracellular Fluid; Kidney; Osmolar Concentration; Peptide Fragments; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1999 |
Noradrenaline stimulates the production of prostaglandin f2alpha in cultured bovine endometrial cells.
Topics: Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprost; Endometrium; Enzyme Activation; Enzyme Inhibitors; Estrenes; Female; Norepinephrine; ortho-Aminobenzoates; Oxytocin; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrrolidinones; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1999 |
Expression of cytokine mRNA during immuno-modulation of murine suppressor macrophages.
Topics: Adjuvants, Immunologic; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cytokines; Gene Expression Regulation; Interferon-gamma; Interleukin-12; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Macrophages; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Protein Kinase C; RNA, Messenger; Signal Transduction; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 1998 |
Transcriptional regulation of the oxytocin receptor gene.
Topics: Breast Neoplasms; Colforsin; Dexamethasone; Estrogens; Female; Gene Expression Regulation; Genes, Reporter; Humans; Mutagenesis, Site-Directed; Nerve Growth Factors; Promoter Regions, Genetic; Receptors, Oxytocin; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
[Intracellular regulation of neuronal nicotinic cholinergic receptors].
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Receptors, Nicotinic; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Leptin modulates the glucocorticoid-induced ovarian steroidogenesis.
Topics: 20-alpha-Dihydroprogesterone; Animals; Colforsin; Dexamethasone; Female; Follicle Stimulating Hormone; Gene Expression; Genes, jun; Glucocorticoids; Granulosa Cells; Leptin; Ovary; Pregnenolone; Progesterone; Proteins; Rats; Receptors, Glucocorticoid; Response Elements; Steroids; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Phosphorylation-mediated activation and translocation of the cyclic AMP-specific phosphodiesterase PDE4D3 by cyclic AMP-dependent protein kinase and mitogen-activated protein kinases. A potential mechanism allowing for the coordinated regulation of PDE4D
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Enzyme Activation; Enzyme Inhibitors; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1999 |
Cyclic adenosine-3',5'-monophosphate-mediated activation of a glutamine synthetase composite glucocorticoid response element.
Topics: Activating Transcription Factor 1; Animals; Base Sequence; Cell Line; CHO Cells; Colforsin; COS Cells; Cricetinae; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Drug Synergism; Glucocorticoids; Glutamate-Ammonia Ligase; Hydrocortisone; Molecular Sequence Data; Promoter Regions, Genetic; Response Elements; Tetradecanoylphorbol Acetate; Transcription Factors | 1999 |
Adhesion of human monocytic THP-1 cells to endothelial cell adhesion molecules or extracellular matrix proteins via beta1 integrins regulates heparin binding epidermal growth factor-like growth factor (HB-EGF) expression.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Colforsin; COS Cells; E-Selectin; Endothelium, Vascular; Epidermal Growth Factor; Extracellular Matrix Proteins; Gene Expression Regulation; Heparin; Heparin-binding EGF-like Growth Factor; Humans; Integrin beta1; Intercellular Adhesion Molecule-1; Intercellular Signaling Peptides and Proteins; Monocytes; Phorbol 12,13-Dibutyrate; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Vascular Cell Adhesion Molecule-1 | 1999 |
Effects of PKA and PKC modulators on high affinity glutamate uptake in primary neuronal cell cultures from rat cerebral cortex.
Topics: Alkaloids; Animals; Benzophenanthridines; Biological Transport; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Fetus; Glutamic Acid; Isoquinolines; Kinetics; Neurons; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate | 1999 |
The p38 mitogen-activated protein kinase cascade is not required for the stimulation of insulin secretion from rat islets of Langerhans.
Topics: Animals; Arsenites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cells, Cultured; Colforsin; Enzyme Inhibitors; Glucose; Homeostasis; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Compounds; Sorbitol; Tetradecanoylphorbol Acetate; Vanadates | 1999 |
Iodide symporter gene expression in normal and transformed rat thyroid cells.
Topics: Animals; Blotting, Northern; Carrier Proteins; Cell Transformation, Neoplastic; Colforsin; Cyclic AMP; Down-Regulation; Gene Expression Regulation; Insulin; Iodides; Iodine; Membrane Proteins; Rats; RNA, Messenger; Symporters; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Tumor Cells, Cultured; Up-Regulation | 1999 |
cAMP enhances insulin secretion by an action on the ATP-sensitive K+ channel-independent pathway of glucose signaling in rat pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Calcium; Colforsin; Cyclic AMP; Diazoxide; Enzyme Activation; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium Channels; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate | 1999 |
Genomic organization and chromosomal location of the mouse vasoactive intestinal polypeptide 1 (VPAC1) receptor.
Topics: Animals; Base Sequence; Binding Sites; Chromosome Mapping; Chromosomes; Colforsin; DNA; Exons; Gene Expression Regulation; Genes; Introns; Luciferases; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Molecular Sequence Data; Muridae; PC12 Cells; Promoter Regions, Genetic; Rats; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Polypeptide, Type I; Recombinant Fusion Proteins; Sequence Analysis, DNA; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Divergent mechanisms regulate proliferation/survival and steroidogenesis of theca-interstitial cells.
Topics: 1-Methyl-3-isobutylxanthine; 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Female; Hormone Antagonists; Insulin-Like Growth Factor I; Luteinizing Hormone; Mifepristone; Progesterone; Protein Kinase C; Rats; Rats, Sprague-Dawley; Testosterone; Tetradecanoylphorbol Acetate; Theca Cells | 1999 |
Two human osteoblast-like osteosarcoma cell lines show distinct expression and differential regulation of parathyroid hormone-related protein.
Topics: Colforsin; Exons; Humans; Neoplasm Proteins; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Differential effect of TPA on PGE2 and cicaprost-induced cAMP synthesis in UMR-106 cells.
Topics: Animals; Cell Line; Colforsin; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Sodium Fluoride; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Clonidine inhibits and phorbol acetate activates glutamate release from rat spinal synaptoneurosomes.
Topics: 4-Aminopyridine; Adrenergic alpha-Agonists; Animals; Calcium; Clonidine; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Glutamate Dehydrogenase; Glutamic Acid; In Vitro Techniques; Male; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Spectrometry, Fluorescence; Spinal Cord; Synaptosomes; Tetradecanoylphorbol Acetate | 1999 |
IGF-1 or insulin, and the TSH cyclic AMP cascade separately control dog and human thyroid cell growth and DNA synthesis, and complement each other in inducing mitogenesis.
Topics: Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Dogs; Drug Interactions; Epidermal Growth Factor; Humans; Insulin; Insulin-Like Growth Factor I; Mitogens; Protein Biosynthesis; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1999 |
Regulation of VIP production and secretion by murine lymphocytes.
Topics: Animals; Carcinogens; Cell Division; Cells, Cultured; Colforsin; Dexamethasone; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Feedback; Flow Cytometry; Glucocorticoids; Granulocytes; Interleukin-1; Interleukin-2; Interleukin-6; Isoquinolines; Lymph Nodes; Macrophages, Peritoneal; Male; Mast Cells; Mitogens; Neuroimmunomodulation; Peritoneum; Rats; Rats, Wistar; Retinaldehyde; Sensitivity and Specificity; Spleen; Sulfonamides; Tetradecanoylphorbol Acetate; Thymus Gland; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide | 1999 |
Effect of ceramide on interleukin-6 synthesis in osteoblast-like cells.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Interleukin-1; Interleukin-6; Mice; Osteoblasts; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Tumor Necrosis Factor-alpha | 1999 |
A dominant role for the Raf-MEK pathway in forskolin, 12-O-tetradecanoyl-phorbol acetate, and platelet-derived growth factor-induced CREB (cAMP-responsive element-binding protein) activation, uncoupled from serine 133 phosphorylation in NIH 3T3 cells.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Dual Specificity Phosphatase 1; Dual Specificity Phosphatase 6; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; Flavonoids; Immediate-Early Proteins; MAP Kinase Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphoprotein Phosphatases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Serine; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation | 1999 |
Prostaglandin E2 regulates vitamin D receptor expression, vitamin D-24-hydroxylase activity and cell proliferation in an adherent human myeloid leukemia cell line (Ad-HL60).
Topics: 24,25-Dihydroxyvitamin D 3; Antigens, CD; Calcitriol; Cell Division; Colforsin; Cyclic AMP; Cytochrome P-450 Enzyme System; Dinoprostone; Flow Cytometry; HL-60 Cells; Humans; Phenotype; Receptors, Calcitriol; Steroid Hydroxylases; Tetradecanoylphorbol Acetate; Vitamin D3 24-Hydroxylase | 1999 |
Sequences at the 3' side of the c-fos SRE mediate gene expression via an Sob1-dependent, TCF-independent pathway.
Topics: 3T3 Cells; Animals; Blood Proteins; Colforsin; DNA-Binding Proteins; Fibroblasts; Gene Expression Regulation; Mice; Mutation; Nuclear Proteins; Phosphoproteins; Protein Binding; Proto-Oncogene Proteins c-fos; Response Elements; Serum Response Factor; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Transcriptional regulation of corticotropin-releasing hormone-binding protein gene expression in astrocyte cultures.
Topics: Animals; Astrocytes; Carrier Proteins; Cells, Cultured; Colforsin; Dexamethasone; Gene Expression; Glucocorticoids; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
A common polymorphic allele of the human luteinizing hormone beta-subunit gene: additional mutations and differential function of the promoter sequence.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alleles; Animals; Base Sequence; beta-Galactosidase; Cell Line, Transformed; Colforsin; DNA Mutational Analysis; Ethnicity; Gene Expression Regulation; Gene Frequency; Genes, Reporter; Genotype; Gonadotropin-Releasing Hormone; Humans; Luciferases; Luteinizing Hormone; Mice; Molecular Sequence Data; Pituitary Gland; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Progesterone; Promoter Regions, Genetic; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1999 |
Similar and divergent patterns in the regulation of matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of MMP-1 gene expression in benign and malignant human thyroid cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenocarcinoma, Follicular; Carcinoma; Carcinoma, Papillary; Cells, Cultured; Colforsin; Collagenases; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Humans; Matrix Metalloproteinase 1; Protein Kinase C; Protein-Tyrosine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Thyrotropin; Tissue Inhibitor of Metalloproteinase-1 | 1999 |
Immediate early gene expression in dog thyrocytes in response to growth, proliferation, and differentiation stimuli.
Topics: Animals; Cell Differentiation; Cells, Cultured; Colforsin; DNA; Dogs; Epidermal Growth Factor; Gene Expression Regulation; Genes, Immediate-Early; Growth Substances; Insulin; Insulin-Like Growth Factor I; Kinetics; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Transcription, Genetic; Transcriptional Activation | 1999 |
Triiodothyronine enhances expression of the interleukin-2 receptor alpha chain.
Topics: Cells, Cultured; Colforsin; Concanavalin A; Gene Expression; Humans; Killer Cells, Natural; Leukocytes, Mononuclear; Lymphoma; Receptors, Interleukin-2; Solubility; Tetradecanoylphorbol Acetate; Triiodothyronine; Tumor Cells, Cultured | 1999 |
Regulation of NeuroD expression by activation of the protein kinase-C pathway in Y79 human retinoblastoma cells.
Topics: Adenylate Kinase; Basic Helix-Loop-Helix Transcription Factors; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Humans; Isoenzymes; Nerve Tissue Proteins; Protein Kinase C; Retinoblastoma; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Intracellular regulation of estradiol and progesterone production by cultured bovine granulosa cells.
Topics: Adenylyl Cyclases; Animals; Cattle; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Female; Genistein; Granulosa Cells; Progesterone; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptors, FSH; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1999 |
Cyclic GMP and outer hair cell electromotility.
Topics: Adenylyl Cyclases; Animals; Cell Movement; Colforsin; Cyclic GMP; Dibutyryl Cyclic GMP; Electric Stimulation; Enzyme Activation; Guinea Pigs; Hair Cells, Auditory, Outer; In Vitro Techniques; Phosphorylation; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1999 |
[3H] gamma-aminobutyric acid transport in rat substantia nigra pars reticulata synaptosomes: pharmacological characterization and phorbol ester-induced inhibition.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Basal Ganglia; beta-Alanine; Biological Transport; Carcinogens; Colforsin; Enzyme Inhibitors; GABA Agents; gamma-Aminobutyric Acid; Nipecotic Acids; Proline; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Substantia Nigra; Synaptosomes; Tetradecanoylphorbol Acetate; Tritium | 1999 |
Regulation of HSD17B1 and SRD5A1 in lymphocytes.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; B-Lymphocytes; Cell Line; Cells, Cultured; Colforsin; Gene Expression Regulation, Enzymologic; Humans; Interleukin-4; Interleukin-6; Ionomycin; Jurkat Cells; Lymphocytes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Steroids; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Acute desensitization of nociceptin/orphanin FQ inhibition of voltage-gated calcium channels in freshly dissociated hippocampal neurons.
Topics: Animals; Baclofen; Barium; Calcium; Calcium Channel Blockers; Calcium Channels, P-Type; Carcinogens; Cells, Cultured; Colforsin; Electrophysiology; Extracellular Space; GABA Agonists; Hippocampus; Ion Channel Gating; Membrane Potentials; Nociceptin; Opioid Peptides; Patch-Clamp Techniques; Peptide Fragments; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tetrodotoxin | 1999 |
Roles of atypical protein kinase C in lysophosphatidic acid-induced type II adenylyl cyclase activation in RAW 264.7 macrophages.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Alprostadil; Animals; Calcium; Cell Line; Cholera Toxin; Colchicine; Colforsin; Cyclic AMP; Cytochalasin B; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Indoles; Isoenzymes; Isoproterenol; Lysophosphatidylcholines; Lysophospholipids; Macrophages; Pertussis Toxin; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1999 |
The effect of cytokines on parathyroid hormone-related protein (PTH-rP) production in human amnion cells.
Topics: Amnion; Carcinogens; Cells, Cultured; Colforsin; Humans; Interleukin-1; Interleukin-2; Interleukin-6; Interleukin-8; Interleukins; Parathyroid Hormone-Related Protein; Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate | 1999 |
Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters.
Topics: Acetylcysteine; Animals; Carrier Proteins; Cell Line; Chloroquine; Clathrin; Colforsin; Cycloheximide; Dogs; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocytosis; Enzyme Activation; Humans; Kinetics; Lysosomes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phorbols; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Regulation of 11beta-hydroxysteroid dehydrogenase type 1 gene expression by LH and interleukin-1beta in cultured rat granulosa cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activators; Female; Follicle Stimulating Hormone; Gene Expression Regulation, Enzymologic; Gonadotropin-Releasing Hormone; Granulosa Cells; Hydroxysteroid Dehydrogenases; Interleukin-1; Luteinizing Hormone; Protein Kinase C; Rats; Rats, Wistar; Recombinant Proteins; RNA, Messenger; Stimulation, Chemical; Testosterone; Tetradecanoylphorbol Acetate | 1999 |
Adenosine suppresses protein kinase A- and C-induced enhancement of glutamate release in the hippocampus.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Animals; Animals, Newborn; Carbachol; Carcinogens; Cells, Cultured; Cholinergic Agonists; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dopamine Agonists; Enzyme Activation; Excitatory Postsynaptic Potentials; Exocytosis; Glutamic Acid; Hippocampus; Patch-Clamp Techniques; Protein Kinase C; Rats; Synaptic Transmission; Tetradecanoylphorbol Acetate | 1999 |
Approaches to enhance expression after adenovirus-mediated gene transfer to the carotid artery.
Topics: Activating Transcription Factor 1; Adenoviridae; Animals; beta-Galactosidase; Carotid Arteries; Colforsin; Cytomegalovirus; DNA-Binding Proteins; Endothelium, Vascular; Gene Expression; Gene Transfer Techniques; Humans; NF-kappa B; Promoter Regions, Genetic; Rabbits; Tetradecanoylphorbol Acetate; Tissue Distribution; Transcription Factors | 1999 |
Ca(2+) and extracellular acidification rate responses to parathyroid hormone fragments in rat ROS 17/2 and human SaOS-2 cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Alkaloids; Animals; Benzophenanthridines; Calcium; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Fura-2; Humans; Hydrogen-Ion Concentration; Kinetics; Parathyroid Hormone; Peptide Fragments; Phenanthridines; Protein Kinase C; Rats; Signal Transduction; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1999 |
Evidence for regulation of basic fibroblast growth factor gene expression by photoperiod and melatonin in the ovine pars tuberalis.
Topics: Animals; Cell Line; Cells, Cultured; Colforsin; Fibroblast Growth Factor 2; Gene Expression Regulation; Male; Melatonin; Photoperiod; Pituitary Gland, Anterior; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seasons; Sheep; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Mechanisms underlying endothelin's inhibition of FSH-stimulated progesterone production by ovarian granulosa cells.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Cytosol; Endothelin-1; Enzyme Activation; Female; Follicle Stimulating Hormone; Granulosa Cells; Inositol Phosphates; Kinetics; Progesterone; Swine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1999 |
Synergistic action of upstream elements and a promoter-proximal CRE is required for neuroendocrine cell-specific expression and second-messenger regulation of the gene encoding the human secretory protein secretogranin II.
Topics: Base Sequence; Cell Line; Chromogranins; Cloning, Molecular; Colforsin; Cyclic AMP; Gene Expression Regulation; Genes; Humans; Molecular Sequence Data; Neurosecretory Systems; Promoter Regions, Genetic; Proteins; Response Elements; RNA, Messenger; Second Messenger Systems; Sequence Analysis, DNA; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Activation of the small G protein Rap1 in dog thyroid cells by both cAMP-dependent and -independent pathways.
Topics: Animals; Carbachol; Cattle; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dogs; Epidermal Growth Factor; Humans; Insulin; Kinetics; Myocardium; rap1 GTP-Binding Proteins; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 2000 |
Synergistic induction of pituitary adenylate cyclase-activating polypeptide (PACAP) gene expression by nerve growth factor and PACAP in PC12 cells.
Topics: Animals; Blotting, Northern; Colforsin; Drug Synergism; Enzyme Inhibitors; Gene Expression; Mice; Nerve Growth Factor; Neuropeptides; PC12 Cells; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2000 |
Regulation of inducible cAMP early repressor expression by gastrin and cholecystokinin in the pancreatic cell line AR42J.
Topics: Animals; Benzodiazepinones; Cell Line; Cholecystokinin; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Epidermal Growth Factor; Gastrins; Gene Expression Regulation; Nerve Growth Factor; Pancreas; PC12 Cells; Phenylurea Compounds; Phosphorylation; Rats; Repressor Proteins; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2000 |
[Studies on cell signaling immunomodulated murine peritoneal suppressor macrophages: LPS and PMA mediate the activation of RAF-1, MAPK p44 and MAPK p42 and p38 MAPK].
Topics: Animals; Colforsin; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotransferases; Proto-Oncogene Proteins c-raf; Signal Transduction; Tetradecanoylphorbol Acetate | 1997 |
The role of phosphodiesterase in mediating the effect of protein kinase C on cyclic AMP accumulation upon kappa-opioid receptor stimulation in the rat heart.
Topics: 1-Methyl-3-isobutylxanthine; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alkaloids; Animals; Benzophenanthridines; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Male; Myocardium; Phenanthridines; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Tetradecanoylphorbol Acetate | 2000 |
Chloride fluxes activated by parathyroid hormone in human erythrocytes.
Topics: Adult; Chlorides; Colforsin; Erythrocytes; Fluorescence; Fluorescent Dyes; Humans; Ion Transport; Parathyroid Hormone; Quinolinium Compounds; Tetradecanoylphorbol Acetate | 2000 |
Thyrotropin stimulates progesterone secretion by luteal cells by activation of the cAMP/protein kinase A signaling system: a potential involvement of protein kinase C.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Luteal Cells; Progesterone; Protein Kinase C; Signal Transduction; Swine; Tetradecanoylphorbol Acetate; Thyrotropin | 1998 |
Regulation of mouse delta-opioid receptor gene transcription: involvement of the transcription factors AP-1 and AP-2.
Topics: 1-Methyl-3-isobutylxanthine; Aged; Animals; Carcinogens; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Genetic Complementation Test; Glioma; Humans; Mice; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Protein Kinase C; Receptor Cross-Talk; Receptors, Opioid, delta; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Histamine H(3) receptors mediate inhibition of noradrenaline release from intestinal sympathetic nerves.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Calcium; Colforsin; Dose-Response Relationship, Drug; Ethylmaleimide; Guinea Pigs; Histamine; Histamine Agonists; Histamine Antagonists; Ileum; In Vitro Techniques; Intestinal Mucosa; Intestines; Male; Muscle, Smooth; Myenteric Plexus; Nifedipine; Norepinephrine; omega-Conotoxins; Pertussis Toxin; Phenols; Receptors, Histamine H3; Rolipram; Sympathetic Nervous System; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetrodotoxin; Virulence Factors, Bordetella; Yohimbine | 2000 |
Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4.
Topics: 3T3 Cells; ADAM Proteins; ADAM17 Protein; Animals; Clone Cells; Cloning, Molecular; Colforsin; Disintegrins; Drosophila Proteins; ErbB Receptors; Kinetics; Marine Toxins; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Oxazoles; Protein Isoforms; Receptor, ErbB-4; Recombinant Proteins; Substrate Specificity; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tumor Necrosis Factor-alpha; Vanadates | 2000 |
Direct measurement of hormone-induced acidification in intact bone.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Animals, Newborn; Bone and Bones; Bone Neoplasms; Bucladesine; Calcium Signaling; Carbonic Anhydrases; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Extracellular Space; Humans; Hydrogen-Ion Concentration; Mice; Organ Culture Techniques; Organ Specificity; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Second Messenger Systems; Skull; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 2000 |
Novel action of pituitary adenylate cyclase-activating polypeptide. Stimulation of extracellular acidification in rat pituitary GH4C1 cells.
Topics: Animals; Calcium; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Flavonoids; Hydrogen-Ion Concentration; Kinetics; Mitogen-Activated Protein Kinases; Naphthalenes; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Protein Kinase C; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 2000 |
Transcriptional and post-transcriptional regulation of monocyte chemoattractant protein-3 gene expression in human endothelial cells by phorbol ester and cAMP signalling.
Topics: Adenylyl Cyclases; Cells, Cultured; Chemokine CCL7; Colforsin; Cyclic AMP; Cycloheximide; Cytokines; Dactinomycin; Endothelium, Vascular; Enzyme Activation; Gene Expression Regulation; Humans; Monocyte Chemoattractant Proteins; Protein Kinase C; Protein Synthesis Inhibitors; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2000 |
Antithrombotic regulation in human endothelial cells by fibrinolytic factors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Autocrine Communication; Blood Coagulation; Blotting, Northern; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Fibrin; Fibrinolysis; Gene Expression Regulation; Hot Temperature; Humans; Plasminogen Activator Inhibitor 1; Protein Kinase C; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Umbilical Veins; Urokinase-Type Plasminogen Activator | 2000 |
Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide.
Topics: Animals; Bodily Secretions; Carbachol; Cells, Cultured; Colforsin; Down-Regulation; Drug Interactions; Glucose; Guanidines; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Potassium Chloride; Rats; Tetradecanoylphorbol Acetate; Time Factors; Tolbutamide | 2000 |
Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin.
Topics: Androstadienes; Animals; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dogs; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Growth Substances; Hepatocyte Growth Factor; Insulin; Kinetics; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Sirolimus; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Wortmannin | 2000 |
Influence of proliferation, differentiation and dedifferentiation factors on the expression of the lysosomal cysteine proteinase cathepsin L (CL) in thyroid cancer cell lines.
Topics: Adenocarcinoma, Follicular; Carcinoma; Cathepsin L; Cathepsins; Cell Differentiation; Cell Division; Colforsin; Cysteine Endopeptidases; Endopeptidases; Enzyme Induction; Enzyme Precursors; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Insulin; Lysosomes; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Thyrotropin; Tumor Cells, Cultured | 2000 |
Expression of phosphodiesterase 4D (PDE4D) is regulated by both the cyclic AMP-dependent protein kinase and mitogen-activated protein kinase signaling pathways. A potential mechanism allowing for the coordinated regulation of PDE4D activity and expression
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Cycloheximide; Dactinomycin; Enzyme Inhibitors; Isoquinolines; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Rats; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate | 2000 |
Synergism of protein kinase A, protein kinase C, and myosin light-chain kinase in the secretory cascade of the pancreatic beta-cell.
Topics: Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytoplasmic Granules; Drug Synergism; Insulin; Insulin Secretion; Intracellular Membranes; Islets of Langerhans; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tissue Distribution | 2000 |
TSH and cAMP do not signal mitogenesis through Ras activation.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cell Cycle; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dogs; Enzyme Activation; Epidermal Growth Factor; Guanosine Triphosphate; Hepatocyte Growth Factor; Insulin; Mitogens; ras Proteins; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors | 2000 |
Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155.
Topics: 14-3-3 Proteins; Animals; Antibodies; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Cells, Cultured; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Humans; Insulin-Like Growth Factor I; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Serine; Tetradecanoylphorbol Acetate; Transfection; Tyrosine 3-Monooxygenase | 2000 |
Nucleoredoxin, glutaredoxin, and thioredoxin differentially regulate NF-kappaB, AP-1, and CREB activation in HEK293 cells.
Topics: 3T3 Cells; Animals; Blotting, Western; Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Fluorescent Antibody Technique, Indirect; Fungal Proteins; Gene Expression Regulation; Glutaredoxins; Humans; MAP Kinase Kinase Kinase 1; Mice; NF-kappa B; Nuclear Proteins; Oxidation-Reduction; Oxidoreductases; Plasmids; Protein Serine-Threonine Kinases; Proteins; Saccharomyces cerevisiae Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Thioredoxins; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 2000 |
Regulation of the diabetes-associated autoantigen IA-2 in INS-1 pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Autoantigens; Colforsin; Cyclic AMP; Gene Expression Regulation; Glucagon; Glucose; Insulinoma; Islets of Langerhans; Kinetics; Membrane Proteins; Pancreatic Neoplasms; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Regulation of AP1 (Jun/Fos) factor expression and activation in ovarian granulosa cells. Relation of JunD and Fra2 to terminal differentiation.
Topics: Animals; Cell Differentiation; Cells, Cultured; Colforsin; DNA; DNA-Binding Proteins; Female; Follicle Stimulating Hormone; Fos-Related Antigen-2; Granulosa Cells; Immunohistochemistry; Luteinizing Hormone; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Transgenes | 2000 |
Follicle-Stimulating hormone (FSH) stimulates phosphorylation and activation of protein kinase B (PKB/Akt) and serum and glucocorticoid-lnduced kinase (Sgk): evidence for A kinase-independent signaling by FSH in granulosa cells.
Topics: Animals; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; Follicle Stimulating Hormone; Granulosa Cells; Guanine Nucleotide Exchange Factors; Immediate-Early Proteins; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; Protozoan Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Testosterone; Tetradecanoylphorbol Acetate | 2000 |
Extracellular Ca2+ sensitivity of mGluR1alpha induces an increase in the basal cAMP level by direct coupling with Gs protein in transfected CHO cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Calcium; Cell Size; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Fluorescent Dyes; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Isoquinolines; MAP Kinase Signaling System; Protein Kinase C; Receptors, Metabotropic Glutamate; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases | 2000 |
Phorbol ester-regulated cleavage of normal prion protein in HEK293 human cells and murine neurons.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Bucladesine; Carcinogens; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Humans; Kinetics; Methanol; Mice; Molecular Sequence Data; Neurons; Phorbol 12,13-Dibutyrate; Phorbol Esters; Precipitin Tests; Prions; Protein Isoforms; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Up-Regulation | 2000 |
Differential regulation of granule-to-granule and granule-to-plasma membrane fusion during secretion from rat pituitary lactotrophs.
Topics: Animals; Cell Membrane; Colforsin; Cytoplasmic Granules; Exocytosis; Intracellular Membranes; Ionomycin; Male; Membrane Fusion; Microscopy, Electron; Microscopy, Fluorescence; Pituitary Gland, Anterior; Potassium; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 2000 |
Inhibition by adrenomedullin of arginine vasopressin-activated mitogen-activated protein kinase in rat glomerular mesangial cells via cAMP production.
Topics: Adrenomedullin; Animals; Antihypertensive Agents; Arginine Vasopressin; Blotting, Western; Calcium; Carcinogens; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Isoquinolines; Male; Mitogen-Activated Protein Kinases; Peptides; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1996 |
Differential in vitro secretion of gonadotropin-releasing hormone (GnRH) and [hydroxyproline]GnRH from the rat hypothalamus during postnatal development.
Topics: Adenylyl Cyclases; Aging; Animals; Colforsin; Enzyme Activation; Female; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Male; Potassium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sexual Maturation; Tetradecanoylphorbol Acetate | 2000 |
Augmentation of basal insulin release from rat islets by preexposure to a high concentration of glucose.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Calcium; Cell Membrane Permeability; Cells, Cultured; Clonidine; Colforsin; Diazoxide; Dose-Response Relationship, Drug; Electroporation; Glucose; Guanosine Diphosphate; Insulin; Insulin Secretion; Intracellular Fluid; Islets of Langerhans; Male; Mannoheptulose; Mycophenolic Acid; Oligomycins; Potassium; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thionucleotides | 2000 |
Heterologous desensitization of response mediated by selective PKC-dependent phosphorylation of G(i-1) and G(i-2).
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; Hormones; Isoenzymes; Muscle, Smooth; Naphthalenes; Phospholipase C beta; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Kinase C; Rabbits; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2000 |
Identification of overlapping AP-2/NF-kappa B-responsive elements on the rat cholecystokinin gene promoter.
Topics: Animals; Base Sequence; Binding, Competitive; Cholecystokinin; Colforsin; Consensus Sequence; Deoxyribonuclease I; DNA; DNA Footprinting; DNA-Binding Proteins; HeLa Cells; Humans; Molecular Sequence Data; Mutation; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Rats; Response Elements; Tetradecanoylphorbol Acetate; Transcription Factor AP-2; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2001 |
Precisely positioned nucleosomes are not essential for c-fos gene regulation in vivo.
Topics: Animals; Cell Line; Chromatin; Colforsin; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation; Herpesvirus 4, Human; Humans; Ionomycin; Jurkat Cells; Luciferases; Mice; Nucleosomes; Plasmids; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Recombinant Fusion Proteins; RNA Polymerase II; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Thyroid oxidase (THOX2) gene expression in the rat thyroid cell line FRTL-5.
Topics: Amino Acid Sequence; Animals; Antithyroid Agents; Blotting, Northern; Carcinogens; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP; DNA, Complementary; Exons; Female; Flavoproteins; Humans; Hydrogen Peroxide; Iodide Peroxidase; Methimazole; Molecular Sequence Data; Peroxidase; Protein Structure, Tertiary; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors; Tissue Distribution | 2000 |
Somatostatin receptor subtype-5 mediates inhibition of peptide YY secretion from rat intestinal cultures.
Topics: Animals; Carcinogens; Cells, Cultured; Colforsin; Epithelial Cells; Gastrin-Releasing Peptide; Hormones; Intestinal Mucosa; Intestines; Nitrendipine; Peptide YY; Peptides, Cyclic; Protein Kinase C; Rats; Rats, Wistar; Receptors, Somatostatin; Signal Transduction; Somatostatin; Somatostatin-28; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Vasodilator Agents | 2000 |
Pimobendan inhibits the activation of transcription factor NF-kappaB: a mechanism which explains its inhibition of cytokine production and inducible nitric oxide synthase.
Topics: Amrinone; Animals; Cardiotonic Agents; Colforsin; Cytokines; Humans; Interleukin-1; Luciferases; Macrophages; Mice; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphodiesterase Inhibitors; Pyrazines; Pyridazines; Quinolines; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts.
Topics: Animals; Biological Clocks; Bucladesine; Calcimycin; Cell Cycle Proteins; Cell Line; Circadian Rhythm; Colforsin; Culture Media; Dimethyl Sulfoxide; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; Insulin; Nuclear Proteins; Okadaic Acid; Period Circadian Proteins; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 2000 |
Imidacloprid, thiacloprid, and their imine derivatives up-regulate the alpha 4 beta 2 nicotinic acetylcholine receptor in M10 cells.
Topics: Animals; Cell Line; Colforsin; Cycloheximide; Fibroblasts; Imidazoles; Insecticides; Mice; Neonicotinoids; Nicotine; Nitro Compounds; Pyridines; Receptors, Nicotinic; Tetradecanoylphorbol Acetate; Thiazines; Transfection; Tritium; Up-Regulation | 2000 |
Modulation of CD157 expression in multi-lineage myeloid differentiation of promyelocytic cell lines.
Topics: ADP-ribosyl Cyclase; Antigens, CD; Bucladesine; Calcitriol; Cell Differentiation; Cell Line; Cell Lineage; Cell Separation; Cells, Cultured; Colforsin; Detergents; Dose-Response Relationship, Drug; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Flow Cytometry; GPI-Linked Proteins; Granulocytes; HL-60 Cells; Humans; Immunoblotting; Kinetics; Macrophage-1 Antigen; Membrane Glycoproteins; Monocytes; Octoxynol; Phenotype; Phosphorylation; Polyethylene Glycols; Precipitin Tests; Protein-Tyrosine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells; Up-Regulation | 2000 |
The inducible cAMP early repressor ICERIIgamma inhibits CREB and AP-1 transcription but not AT1 receptor gene expression in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Becaplermin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Repressor Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection | 2000 |
Parathyroid hormone-related protein down-regulates bone sialoprotein gene expression in cementoblasts: role of the protein kinase A pathway.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Dental Cementum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Integrin-Binding Sialoprotein; Kinetics; Parathyroid Hormone-Related Protein; Phorbol 12,13-Dibutyrate; Proteins; RNA, Messenger; Second Messenger Systems; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Thionucleotides | 2000 |
Intracellular calcium and protein kinase C mediate expression of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in osteoblasts.
Topics: 3T3 Cells; Animals; Animals, Newborn; Blotting, Northern; Bone Marrow Cells; Calcium; Carrier Proteins; Cell Line; Coculture Techniques; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gene Expression Regulation; Glycoproteins; Ionomycin; Male; Membrane Glycoproteins; Mice; Mice, Inbred Strains; Osteoblasts; Osteoclasts; Osteoprotegerin; Protein Kinase C; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; RNA, Messenger; Signal Transduction; Stromal Cells; Tetradecanoylphorbol Acetate | 2000 |
The differential molecular mechanisms underlying proenkephalin mRNA expression induced by forskolin and phorbol-12-myristic-13-acetate in primary cultured astrocytes.
Topics: Animals; Astrocytes; Blotting, Western; Cells, Cultured; Colforsin; Cyclic AMP Response Element-Binding Protein; Dexamethasone; DNA; Enkephalins; Phosphorylation; Protein Precursors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Response Elements; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation | 2000 |
Regulation of aromatase expression in human ovarian surface epithelial cells.
Topics: 5' Untranslated Regions; Adult; Androstenedione; Aromatase; Blotting, Southern; Carcinogens; Cell Line; Colforsin; Dexamethasone; DNA; Epithelial Cells; Female; Gene Expression Regulation, Enzymologic; Glucocorticoids; Humans; Kinetics; Ovary; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2000 |
Galanin receptor 1 gene expression is regulated by cyclic AMP through a CREB-dependent mechanism.
Topics: Animals; Base Sequence; Cell Line; Cloning, Molecular; Codon, Initiator; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Growth Factor; Neurons; Promoter Regions, Genetic; Receptors, Galanin; Receptors, Neuropeptide; Regulatory Sequences, Nucleic Acid; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Pharmacological modulation of nerve growth factor synthesis: a mechanistic comparison of vitamin D receptor and beta(2)-adrenoceptor agonists.
Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antineoplastic Agents; Calcitriol; Carcinogens; Clenbuterol; Colforsin; Gene Expression; Mice; Nerve Growth Factor; NF-kappa B; Propranolol; Receptors, Calcitriol; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic | 2000 |
Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone in human granulosa-luteal cells.
Topics: Cells, Cultured; Cholera Toxin; Colforsin; Corpus Luteum; Cyclic AMP; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; Female; Gonadotropin-Releasing Hormone; Granulosa Cells; Hormone Antagonists; Humans; Mitogen-Activated Protein Kinases; Oligopeptides; Pertussis Toxin; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors; Virulence Factors, Bordetella | 2001 |
Regulation of neuregulin expression in the injured rat brain and cultured astrocytes.
Topics: Animals; Astrocytes; Brain Injuries; Cells, Cultured; Cerebral Cortex; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Glial Fibrillary Acidic Protein; Head Injuries, Penetrating; Neuregulins; Protein Isoforms; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Receptor, ErbB-3; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 2001 |
Reduced neuritic outgrowth and cell adhesion in neuronal cells transfected with human alpha-synuclein.
Topics: alpha-Synuclein; Animals; beta-Synuclein; Cell Adhesion; Cell Differentiation; Cell Line; Colforsin; Humans; Immunohistochemistry; Nerve Tissue Proteins; Neurites; Neurons; Rats; Synucleins; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Isolation and characterization of the human CLC-5 chloride channel gene promoter.
Topics: Animals; Base Sequence; Binding Sites; Cell Line; Chloride Channels; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cyclic AMP; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Luciferases; Molecular Sequence Data; Mutation; Parathyroid Hormone; Promoter Regions, Genetic; Protein Binding; Recombinant Fusion Proteins; RNA Splicing; Sequence Analysis, DNA; Sequence Deletion; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription Factor AP-1; Transcription, Genetic | 2000 |
The growth hormone-releasing hormone receptor: desensitisation following short-term agonist exposure.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Bucladesine; Cells, Cultured; Colforsin; Cricetinae; Dose-Response Relationship, Drug; Down-Regulation; Humans; Kidney; Male; Pituitary Gland; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide; Receptors, Pituitary Hormone-Regulating Hormone; Sermorelin; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Differential effects of agonists of aldosterone secretion on steroidogenic acute regulatory phosphorylation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Blotting, Western; Calcium Channel Agonists; Cattle; Cells, Cultured; Colforsin; Electrophoresis, Gel, Two-Dimensional; Phosphoproteins; Phosphorylation; Potassium Chloride; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Zona Glomerulosa | 2001 |
Characterization of adenylyl cyclases in cultured human granulosa cells.
Topics: Adenylyl Cyclases; Calcimycin; Calcium; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Female; Granulosa Cells; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoenzymes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 2001 |
The cAMP responsive element and CREB partially mediate the response of the tyrosine hydroxylase gene to phorbol ester.
Topics: Animals; Binding Sites; Chloramphenicol O-Acetyltransferase; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation, Enzymologic; Kinetics; PC12 Cells; Phosphorylation; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription Factor AP-1; Transcription, Genetic; Transfection; Tyrosine 3-Monooxygenase | 2001 |
Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel.
Topics: 1-Methyl-3-isobutylxanthine; Acids; Animals; Barium Compounds; Bupivacaine; Cell Line; Cesium; Chlorides; Colforsin; Dose-Response Relationship, Drug; Female; Gene Expression; Glyburide; Halothane; Humans; Kinetics; Membrane Potentials; Oocytes; Potassium; Potassium Channels; Potassium Channels, Tandem Pore Domain; Pregnanediones; Tetradecanoylphorbol Acetate; Tetraethylammonium; Time Factors; Xenopus | 2001 |
The differential regulation of CART gene expression in a pituitary cell line and primary cell cultures of ovine pars tuberalis cells.
Topics: Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Gene Expression Regulation; Hypothalamus; In Situ Hybridization; Median Eminence; Nerve Tissue Proteins; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Pituitary Gland, Anterior; Protein Kinase C; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Second Messenger Systems; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 2001 |
Defective stimulus-secretion coupling in islets of Psammomys obesus, an animal model for type 2 diabetes.
Topics: Animals; Colforsin; Diabetes Mellitus, Type 2; Diazoxide; Disease Models, Animal; Disease Susceptibility; Gerbillinae; Glucagon; Glucagon-Like Peptide 1; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Oxidation-Reduction; Peptide Fragments; Protein Kinase C; Protein Precursors; Rats; Rats, Sprague-Dawley; Reference Values; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
Modulation of rat erg1, erg2, erg3 and HERG K+ currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade.
Topics: Animals; Arachidonic Acid; Cation Transport Proteins; Cells, Cultured; Cholecystokinin; Colforsin; DNA-Binding Proteins; Enzyme Inhibitors; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Flavonoids; Humans; Indoles; Isoquinolines; Kinetics; Maleimides; Membrane Potentials; Membrane Transport Proteins; Patch-Clamp Techniques; Pituitary Gland, Anterior; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase Inhibitors; Protein Kinases; Rats; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Trans-Activators; Transcriptional Regulator ERG; Tyrphostins; Vasoactive Intestinal Peptide | 2001 |
NID67, a small putative membrane protein, is preferentially induced by NGF in PC12 pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Base Sequence; Calcimycin; Calcium; Cell Differentiation; Chromosomes, Human, Pair 5; Colforsin; Culture Media, Serum-Free; DNA, Complementary; DNA, Neoplasm; Epidermal Growth Factor; Female; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Humans; Ion Channels; Ionophores; Membrane Proteins; Mice; Molecular Sequence Data; Myocardium; Neoplasm Proteins; Nerve Growth Factor; Nerve Tissue Proteins; Open Reading Frames; Organ Specificity; Ovary; PC12 Cells; Pheochromocytoma; Polymerase Chain Reaction; Potassium Chloride; Protein Structure, Tertiary; Rats; Second Messenger Systems; Sequence Alignment; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate | 2001 |
RGS2: regulation of expression and nuclear localization.
Topics: Carbachol; Cell Differentiation; Cell Line; Cell Nucleus; Cholinergic Agonists; Colforsin; Culture Media; Cyclic AMP; Gene Expression Regulation; Green Fluorescent Proteins; Heat-Shock Response; Humans; Luminescent Proteins; Neuroblastoma; Neurons; Protein Kinase C; Recombinant Fusion Proteins; RGS Proteins; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Interaction between beta-adrenergic signaling and protein kinase C increases cytoplasmic Ca2+ in alveolar type II cells.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Calcium; Cells, Cultured; Cobalt; Colforsin; Cyclic AMP; Cytoplasm; Diglycerides; Drug Interactions; Epithelial Cells; Male; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Signal Transduction; Specific Pathogen-Free Organisms; Terbutaline; Tetradecanoylphorbol Acetate | 2001 |
Gonadotropins decrease estrogen receptor-beta messenger ribonucleic acid stability in rat granulosa cells.
Topics: Animals; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Dichlororibofuranosylbenzimidazole; Drug Stability; Estrogen Receptor beta; Female; Granulosa Cells; Luteinizing Hormone; Nucleic Acid Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate | 2001 |
Expression of messenger ribonucleic acid for the antiapoptosis gene P11 in the rat ovary: gonadotropin stimulation in granulosa cells of preovulatory follicles.
Topics: Adenylyl Cyclase Inhibitors; Animals; Annexin A2; Apoptosis; Blotting, Northern; Calcium-Binding Proteins; Chorionic Gonadotropin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression; Gonadotropins; Gonadotropins, Equine; Granulosa Cells; Imines; Luteinizing Hormone; Ovarian Follicle; Ovary; Ovulation; Rats; Rats, Sprague-Dawley; RNA, Messenger; S100 Proteins; Sexual Maturation; Tetradecanoylphorbol Acetate | 2001 |
Heterologous sensitization of recombinant adenylate cyclases by activation of D(2) dopamine receptors.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Cell Line; Colforsin; Cyclic AMP; Dopamine Agonists; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gs; Humans; Ionophores; Isoenzymes; Isoproterenol; Kidney; Quinpirole; Receptors, Dopamine D2; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2001 |
Tumor necrosis factor-alpha is induced through phorbol ester--and glycated human albumin-dependent pathway in THP-1 cells.
Topics: Carcinogens; Catalase; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Insulin Resistance; Mitogen-Activated Protein Kinases; Monocytes; Protein Kinase C; Serum Albumin; Signal Transduction; Staurosporine; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Effects of protein kinase C inhibitors on insulin secretory responses from rodent pancreatic islets.
Topics: Animals; Carbachol; Carbazoles; Cholinergic Agonists; Colforsin; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Glucose; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Mice; Potassium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate | 2001 |
Suppression of T-cell responsiveness by inducible cAMP early repressor (ICER).
Topics: Animals; Cell Division; Chemokines; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cytokines; Dinoprostone; DNA-Binding Proteins; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-2; Ionomycin; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Promoter Regions, Genetic; Repressor Proteins; Second Messenger Systems; Spleen; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells; Transcription, Genetic | 2001 |
Pituitary adenylate cyclase-activating polypeptide stimulates secretoneurin release and secretogranin II gene transcription in bovine adrenochromaffin cells through multiple signaling pathways and increased binding of pre-existing activator protein-1-like
Topics: Animals; Binding Sites; Biological Transport; Calcium; Carcinogens; Cattle; Cells, Cultured; Chromaffin Cells; Chromogranin A; Chromogranins; Colforsin; Cycloheximide; Mitogen-Activated Protein Kinases; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium; Protein Kinases; Protein Synthesis Inhibitors; Proteins; Secretogranin II; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription, Genetic | 2001 |
Stimulatory and synergistic effects of luteinising hormone and insulin like growth factor 1 on the secretion of vascular endothelial growth factor and progesterone of cultured bovine granulosa cells.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Dinoprost; Dinoprostone; Drug Synergism; Endothelial Growth Factors; Female; Fibroblast Growth Factor 2; Granulosa Cells; Growth Hormone; Hydrocortisone; Insulin-Like Growth Factor I; Ionophores; Luteinizing Hormone; Lymphokines; Progesterone; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Differential mechanisms of glucose and palmitate in augmentation of insulin secretion in mouse pancreatic islets.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Calcium; Colforsin; Culture Techniques; Enzyme Inhibitors; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Myristic Acid; Naphthalenes; Palmitates; Palmitoyl Coenzyme A; Potassium Channels; Protein Kinase C; Tetradecanoylphorbol Acetate | 2001 |
Biphasic response to human galanin of extracellular acidification in human Bowes melanoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Acids; Amiloride; Cell Line; Colforsin; Dose-Response Relationship, Drug; Extracellular Space; Galanin; Gene Expression; Humans; Hydrogen-Ion Concentration; Melanoma; Peptide Fragments; Pertussis Toxin; Receptors, Galanin; Receptors, Neuropeptide; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 2001 |
Parathyroid hormone receptor internalization is independent of protein kinase A and phospholipase C activation.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Binding Sites; Cell Line; Cell Membrane; Coated Pits, Cell-Membrane; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Cytoplasm; Enzyme Activation; Gene Expression; Green Fluorescent Proteins; Kinetics; Luminescent Proteins; Mutagenesis; Parathyroid Hormone; Phosphorylation; Protein Kinase C; Rats; Receptors, Parathyroid Hormone; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases | 2001 |
Protein kinase C, rather than protein kinase A is involved in follicle-stimulating hormone-mediated meiotic resumption of mouse cumulus cell-enclosed oocytes in hypoxanthine-supplemented medium.
Topics: Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Follicle Stimulating Hormone; Hypoxanthine; Imines; Meiosis; Mice; Oocytes; Protein Kinase C; Tetradecanoylphorbol Acetate | 2001 |
Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Dihydropyridines; Dose-Response Relationship, Drug; Enzyme Activation; Estrenes; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoproterenol; Mice; Mice, Inbred CBA; Pertussis Toxin; Phospholipases; Pinealoma; Pyrrolidinones; Receptor, Adenosine A2B; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Virulence Factors, Bordetella | 2001 |
Identification of specific gravity sensitive signal transduction pathways in human A431 carcinoma cells.
Topics: Calcimycin; Carcinogens; Carcinoma, Squamous Cell; Colforsin; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Gravitation; Humans; Ionophores; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rotation; Signal Transduction; Space Flight; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Weightlessness; Weightlessness Simulation | 1992 |
Altered gravity conditions affect early EGF-induced signal transduction in human epidermal A431 cells.
Topics: Calcimycin; Centrifugation; Colforsin; Epidermal Growth Factor; ErbB Receptors; Gene Expression; Genes, fos; Gravitation; Gravity, Altered; Humans; Protein Kinase C; Receptor Aggregation; Rotation; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Differential effects of forskolin and phobol 12-myristate-13-acetate on the c-fos and c-jun mRNA expression in rat C6 glioma cells.
Topics: Animals; Blotting, Northern; Colforsin; Cycloheximide; Dexamethasone; Gene Expression Regulation; Genes, fos; Genes, jun; Glucocorticoids; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Block by gabapentin of the facilitation of glutamate release from rat trigeminal nucleus following activation of protein kinase C or adenylyl cyclase.
Topics: Acetates; Adenylyl Cyclases; Amines; Analgesics; Animals; Colforsin; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Enzyme Activation; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Potassium; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Trigeminal Nuclei; Tritium | 2001 |
Mechanisms in fluoride-induced interleukin-8 synthesis in human lung epithelial cells.
Topics: Androstadienes; Benzylamines; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Epithelial Cells; Flavonoids; Genistein; Humans; Indoles; Interleukin-8; Isoquinolines; Lung; Maleimides; Okadaic Acid; Pertussis Toxin; Protein Kinase C; Signal Transduction; Sodium Fluoride; Sulfonamides; Tetradecanoylphorbol Acetate; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2001 |
Immortalization of equine trophoblast cell lines of chorionic girdle cell lineage by simian virus-40 large T antigen.
Topics: Analysis of Variance; Animals; Antigens, Polyomavirus Transforming; Carcinogenicity Tests; Cell Line, Transformed; Cell Lineage; Cell Separation; Chorion; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Gene Expression Regulation; Glycoprotein Hormones, alpha Subunit; Gonadotropins, Equine; Horses; Mice; Mice, Nude; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Trophoblasts | 2001 |
Inducible RGS2 is a cross-talk regulator for parathyroid hormone signaling in rat osteoblast-like UMR106 cells.
Topics: Animals; Base Sequence; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Inhibitors; Gene Expression Regulation; Humans; Molecular Sequence Data; Osteoblasts; Parathyroid Hormone; Protein Binding; Rats; RGS Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
The protein kinase C pathway inhibits iodide uptake by calf thyroid cells via sodium potassium-adenosine triphosphatase.
Topics: Animals; Bucladesine; Cattle; Cells, Cultured; Colforsin; Enzyme Inhibitors; Indoles; Iodides; Iodine; Maleimides; Protein Kinase C; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors | 2001 |
Inhibition of the glutamate transporter EAAC1 expressed in Xenopus oocytes by phorbol esters.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Transport System X-AG; Animals; Carcinogens; Carrier Proteins; Cell Membrane; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Transporter 3; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Humans; Indoles; Maleimides; Membrane Potentials; Oocytes; Phorbols; Protein Kinase C; RNA, Complementary; Symporters; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured; Xenopus laevis | 2001 |
Glucose and forskolin regulate IAPP gene expression through different signal transduction pathways.
Topics: Adenylyl Cyclase Inhibitors; Amyloid; Blotting, Northern; Carcinoma, Pancreatic Ductal; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Humans; Islet Amyloid Polypeptide; Isoquinolines; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Antagonizing effect of protein kinase C activation on the mu-opioid agonist-induced inhibition of high voltage-activated calcium current in rat periaqueductal gray neuron.
Topics: Analgesics, Opioid; Animals; Calcium Channels; Calcium Signaling; Carcinogens; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Female; Male; Membrane Potentials; Neurons; Pain; Periaqueductal Gray; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Staurosporine; Synaptic Transmission; Tetradecanoylphorbol Acetate | 2001 |
Alternative splicing of CRH-R1 receptors in human and mouse skin: identification of new variants and their differential expression.
Topics: 1-Methyl-3-isobutylxanthine; Alternative Splicing; Animals; Bucladesine; Cell Line; Colforsin; Gene Expression Regulation; Humans; Protein Isoforms; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured; Ultraviolet Rays | 2001 |
TNF-alpha enhances intracellular glucocorticoid availability.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Cells, Cultured; Colforsin; Corticosterone; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glucocorticoids; Glucose; Hydroxysteroid Dehydrogenases; Imidazoles; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Pyridines; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Histamine increases the expression of LOX-1 via H2 receptor in human monocytic THP-1 cells.
Topics: Bucladesine; Cell Differentiation; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytokines; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation; Histamine; Humans; Isoquinolines; Macrophages; Monocytes; Nuclear Proteins; Promoter Regions, Genetic; Prostaglandin D2; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, LDL; Receptors, Oxidized LDL; RNA, Messenger; Scavenger Receptors, Class E; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured; Up-Regulation | 2001 |
Targeted disruption of the type 2 selenodeiodinase gene (DIO2) results in a phenotype of pituitary resistance to T4.
Topics: Adipose Tissue, Brown; Animals; Astrocytes; Blotting, Northern; Colforsin; Female; Hypothyroidism; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pituitary Gland; Tetradecanoylphorbol Acetate; Thyroid Hormone Resistance Syndrome; Thyrotropin; Thyroxine; Triiodothyronine | 2001 |
Regulation of transepithelial phosphate transport by PTH in chicken proximal tubule epithelium.
Topics: Animals; Biological Transport; Carcinogens; Cells, Cultured; Chickens; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Indoles; Isoquinolines; Kidney Tubules, Proximal; Maleimides; Parathyroid Hormone; Phosphates; Protein Kinase C; Sodium-Phosphate Cotransporter Proteins; Sulfonamides; Symporters; Tetradecanoylphorbol Acetate | 2002 |
PKC and PKA, but not PKG mediate LPS-induced CGRP release and [Ca(2+)](i) elevation in DRG neurons of neonatal rats.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Calcium; Carcinogens; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Ganglia, Spinal; Lipopolysaccharides; Male; Neurogenic Inflammation; Neurons, Afferent; Potassium; Protein Kinase C; Protein Kinases; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Up-Regulation | 2001 |
Identification of signal transduction pathways and promoter sequences that mediate parathyroid hormone 1-38 inhibition of osteoprotegerin gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Colforsin; Gene Expression; Glycoproteins; Osteoblasts; Osteoprotegerin; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Promoter Regions, Genetic; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 2001 |
Pituitary growth hormone secretion in the turbot, a phylogenetically recent teleost, is regulated by a species-specific pattern of neuropeptides.
Topics: Animals; Cells, Cultured; Colforsin; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Drug Synergism; Eels; Flatfishes; Growth Hormone; In Vitro Techniques; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Pituitary Gland, Anterior; Signal Transduction; Somatostatin; Species Specificity; Tetradecanoylphorbol Acetate | 2001 |
A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion.
Topics: Animals; Cell Line; Clone Cells; Colforsin; Gene Expression Regulation, Enzymologic; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Phospholipases A; Proinsulin; Protein Precursors; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thermodynamics; Tolbutamide; Transfection | 2002 |
Regulation of extracellular matrix remodeling and MMP-2 activation in cultured rat adrenal medullary endothelial cells.
Topics: Adrenal Medulla; Animals; Cell Culture Techniques; Colforsin; Egtazic Acid; Endothelium; Enzyme Activation; Extracellular Matrix; Extracellular Matrix Proteins; Matrix Metalloproteinase 2; Rats; Second Messenger Systems; Tetradecanoylphorbol Acetate | 2001 |
The role of protein kinase C-delta in PTH stimulation of IGF-binding protein-5 mRNA in UMR-106-01 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Acetophenones; Animals; Benzopyrans; Cattle; Cell Line; Cell Membrane; Cell Nucleus; Colforsin; Cytosol; Enzyme Inhibitors; Gene Expression; Humans; Insulin-Like Growth Factor Binding Protein 5; Isoenzymes; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Protein Kinase C; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 2002 |
Oxytocin stimulation of RGS2 mRNA expression in cultured human myometrial cells.
Topics: Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Egtazic Acid; Enzyme Activation; Female; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Humans; Inositol Phosphates; Ionophores; Myometrium; Oxytocin; Pregnancy; Protein Kinase C; RGS Proteins; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 2002 |
Time-dependent potentiation of the beta-cell is a Ca2+-independent phenomenon.
Topics: Acylation; Analysis of Variance; Animals; Calcium; Cells, Cultured; Cerulenin; Colforsin; Cyclic AMP; Enzyme Inhibitors; Glucose; Indoles; Insulin; Insulin Secretion; Islets of Langerhans; Male; Maleimides; Naphthalenes; Potassium Chloride; Protein Kinase C; Rats; Rats, Wistar; Statistics, Nonparametric; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors; Tunicamycin | 2002 |
Gonadotropin-releasing hormone stimulates annexin 5 messenger ribonucleic acid expression in the anterior pituitary cells.
Topics: Animals; Annexin A5; Cells, Cultured; Colforsin; Female; Gonadotropin-Releasing Hormone; Kinetics; Luteinizing Hormone; Pituitary Gland, Anterior; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2002 |
Norepinephrine inhibits glucose-stimulated, Ca2+-independent insulin release independently from its action on adenylyl cyclase.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Calcium; Colforsin; Cyclic AMP; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Norepinephrine; Pertussis Toxin; Rats; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 2001 |
Attenuation of protein kinase C and cAMP-dependent protein kinase signal transduction in the neurogranin knockout mouse.
Topics: Animals; Calmodulin-Binding Proteins; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Hippocampus; Immunoblotting; Kinetics; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurogranin; Phosphorylation; Protein Binding; Protein Kinase C; Signal Transduction; Temperature; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Regulation of fibronectin fibrillogenesis by protein kinases in cultured rat osteoblasts.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Fibronectins; Humans; Integrins; Osteoblasts; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 2002 |
Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.
Topics: 1-Methyl-3-isobutylxanthine; 3T3 Cells; Animals; Colforsin; COS Cells; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Genes, Reporter; Mice; Mitogen-Activated Protein Kinases; Peptide Mapping; Phosphodiesterase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-raf; Serine; Signal Transduction; Tetradecanoylphorbol Acetate | 2002 |
Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chromatography, Affinity; Colforsin; COS Cells; Epidermal Growth Factor; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Ligands; Male; MAP Kinase Signaling System; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptides; Phosphopeptides; Phosphorylation; Plasmids; Prostatic Neoplasms; Protein Kinase C; Receptors, Androgen; Serine; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured | 2002 |
Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cell Line; Colforsin; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Peptide Fragments; Pertussis Toxin; Pituitary Gland; Protein Serine-Threonine Kinases; Rats; Receptors, LHRH; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Trypsin; Virulence Factors, Bordetella | 2002 |
Phosphatidylinositol 3-kinase regulates PMA-induced differentiation and superoxide production in HL-60 cells.
Topics: Androstadienes; Apoptosis; Bucladesine; Cell Differentiation; Cell Division; Chromones; Colforsin; Enzyme Inhibitors; HL-60 Cells; Humans; Monocytes; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myc; Ribosomal Protein S6 Kinases, 70-kDa; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin | 2002 |
Cloning of the 5'-flanking region of the murine bone morphogenetic protein-7 gene.
Topics: Animals; Base Sequence; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cells, Cultured; Cloning, Molecular; Colforsin; Dogs; Kidney; Mesoderm; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Swine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta | 2002 |
cis-Acting elements within CFTR 5'-flanking DNA are not sufficient to decrease gene expression in response to phorbol ester.
Topics: 5' Flanking Region; Adenocarcinoma; Animals; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Electrophoresis, Gel, Pulsed-Field; Gene Expression Regulation; Genes, Reporter; Humans; Luciferases; Lung Neoplasms; Promoter Regions, Genetic; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Glial induction of blood-brain barrier-like L-system amino acid transport in the ECV304 cell line.
Topics: Amino Acid Transport System L; Amino Acids; Animals; Astrocytes; Blood-Brain Barrier; Brain; Cholera Toxin; Colforsin; Culture Media, Conditioned; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endothelium, Vascular; Growth Substances; Humans; Leucine; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Ligands for the peroxisomal proliferator-activated receptor gamma and the retinoid X receptor inhibit aromatase cytochrome P450 (CYP19) expression mediated by promoter II in human breast adipose.
Topics: Adipose Tissue; Aromatase; Base Sequence; Chromans; Colforsin; Female; Gene Expression Regulation, Enzymologic; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Tetradecanoylphorbol Acetate; Tetrahydronaphthalenes; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2002 |
Regulation of cellular alpha-MSH and beta-endorphin during stimulated secretion from intermediate pituitary cells: involvement of aspartyl and cysteine proteases in the control of cellular levels of alpha-MSH and beta-endorphin.
Topics: alpha-MSH; Animals; Aspartic Acid Endopeptidases; beta-Endorphin; Colforsin; Cysteine Endopeptidases; Dopamine; Isoproterenol; Male; Pituitary Gland; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2002 |
The role of putative phosphorylation sites in the targeting and shuttling of the aquaporin-2 water channel.
Topics: Amino Acid Sequence; Animals; Aquaporin 2; Aquaporin 6; Aquaporins; Cell Line; Cell Membrane; Colforsin; Dogs; Endocytosis; Humans; Molecular Sequence Data; Phosphorylation; Protein Kinase C; Protein Transport; Serine; Tetradecanoylphorbol Acetate | 2002 |
Arachidonic acid signaling to the cytoskeleton: the role of cyclooxygenase and cyclic AMP-dependent protein kinase in actin bundling.
Topics: 3T3 Cells; Actins; Animals; Arachidonic Acids; Cell Adhesion; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Cytoskeleton; Enzyme Activation; Extracellular Matrix; Fibroblasts; HeLa Cells; Humans; Mice; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Stress Fibers; Tetradecanoylphorbol Acetate | 2002 |
Gene expression profile after intense second messenger activation in cortical primary neurones.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Cocaine; Colforsin; Enzyme Activators; Gene Expression Profiling; Male; Nerve Growth Factors; Neuronal Plasticity; Neurons; Neuropeptides; Oligonucleotide Array Sequence Analysis; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription Factors; Up-Regulation | 2002 |
Characterization and regulation of a CHO cell line stably expressing human serotonin N-acetyltransferase (EC 2.3.1.87).
Topics: 5-Methoxytryptamine; Animals; Arylamine N-Acetyltransferase; Caco-2 Cells; CHO Cells; Chromatography, High Pressure Liquid; Colforsin; Cricetinae; Enzyme Inhibitors; Humans; Phenethylamines; Recombinant Proteins; Serotonin; Tetradecanoylphorbol Acetate; Transgenes; Tritium | 2002 |
Cellular mechanisms of nociception in the frog.
Topics: Acids; Age Factors; Animals; Capsaicin; Carcinogens; Cells, Cultured; Colforsin; Ganglia, Spinal; Hot Temperature; Hydrogen-Ion Concentration; Male; Membrane Potentials; Neurons, Afferent; Nociceptors; Rana pipiens; Tetradecanoylphorbol Acetate | 2002 |
Neuronal activity is required for the circadian rhythm of vasopressin gene transcription in the suprachiasmatic nucleus in vitro.
Topics: Animals; Arginine Vasopressin; Circadian Rhythm; Colforsin; Gene Expression; In Situ Hybridization; Neurons; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; RNA, Heterogeneous Nuclear; RNA, Messenger; Sodium Channel Blockers; Suprachiasmatic Nucleus; Tetradecanoylphorbol Acetate; Tetrodotoxin; Transcription, Genetic | 2002 |
The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia.
Topics: Aged; Amino Acid Sequence; Amino Acid Substitution; Animals; Arrhythmias, Cardiac; Base Sequence; Blotting, Western; Cation Transport Proteins; Cell Line; Colforsin; COS Cells; DNA; DNA Mutational Analysis; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Genotype; Histamine H1 Antagonists; Humans; Immunohistochemistry; Male; Membrane Potentials; Molecular Sequence Data; Polymorphism, Single Nucleotide; Polymorphism, Single-Stranded Conformational; Potassium Channels; Potassium Channels, Voltage-Gated; Pruritus; Sequence Homology, Amino Acid; Terfenadine; Tetradecanoylphorbol Acetate; Trans-Activators; Transcriptional Regulator ERG | 2002 |
Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner.
Topics: Animals; Antipsychotic Agents; Calcimycin; Calcium; Calcium Channel Blockers; Cell Line; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Chlorpromazine; Clozapine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Haloperidol; Histamine; Histamine H1 Antagonists; Ionophores; Mammary Tumor Virus, Mouse; Mice; Nifedipine; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinase C-alpha; Pyrilamine; Pyrrolidinones; Raclopride; Receptors, Glucocorticoid; Remoxipride; Sulfonamides; Sulpiride; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Type C Phospholipases | 2002 |
Specific up-regulation of CRH or AVP secretion by acetylcholine or lipopolysaccharide in inflammatory susceptible Lewis rat fetal hypothalamic cells.
Topics: Acetylcholine; Animals; Arginine Vasopressin; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Dose-Response Relationship, Drug; Hypothalamus; Inflammation; Interleukin-1; Interleukin-6; Lipopolysaccharides; Rats; Rats, Inbred F344; Rats, Inbred Lew; Serotonin; Species Specificity; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation | 2002 |
Different roles for Gi and Go proteins in modulation of adenylyl cyclase type-2 activity.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Humans; Idazoxan; Pertussis Toxin; Protein Kinase C; Receptors, Adrenergic, alpha-2; Signal Transduction; Spodoptera; Tetradecanoylphorbol Acetate | 2002 |
Transactivation of the progesterone receptor gene in granulosa cells: evidence that Sp1/Sp3 binding sites in the proximal promoter play a key role in luteinizing hormone inducibility.
Topics: Animals; Base Sequence; Binding Sites; CCAAT-Binding Factor; Colforsin; Conserved Sequence; Electrophoretic Mobility Shift Assay; Female; Granulosa Cells; Luteinizing Hormone; Molecular Sequence Data; Mutagenesis, Site-Directed; Ovulation; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 2003 |
Hormone-regulated expression and localization of versican in the rodent ovary.
Topics: Animals; Cells, Cultured; Chondroitin Sulfate Proteoglycans; Chorionic Gonadotropin; Colforsin; Cyclooxygenase 2; Estradiol; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Granulosa Cells; Hormones; In Situ Hybridization; Isoenzymes; Lectins, C-Type; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovarian Follicle; Ovary; Ovulation; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; RNA, Messenger; Signal Transduction; Testosterone; Tetradecanoylphorbol Acetate; Versicans | 2003 |
Interferon-gamma stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2. A potentially novel pathway for interferon-gamma-mediated inhibition of gene transcription.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Apigenin; Blotting, Western; Calcimycin; Calcium; Casein Kinase II; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Genetic Vectors; Imidazoles; Indoles; Interferon-gamma; Macrophages; Maleimides; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transcription, Genetic; Transcriptional Activation; Tyrphostins | 2003 |
Regulation of matrix metalloproteinase-9 (MMP-9), tissue inhibitor of MMP, and progesterone secretion in luteinized granulosa cells from normally ovulating women with polycystic ovary disease.
Topics: Adult; Blotting, Western; Colforsin; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Female; Granulosa Cells; Humans; Luteinization; Matrix Metalloproteinase 9; Polycystic Ovary Syndrome; Progesterone; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1 | 2003 |
Calcitonin inhibits proton extrusion in resorbing rat osteoclasts via protein kinase A.
Topics: Animals; Bone Resorption; Bucladesine; Calcitonin; Carcinogens; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Hydrogen-Ion Concentration; Osteoclasts; Proton Pumps; Protons; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 2003 |
Protein kinase A- and C-induced insulin release from Ca2+ -insensitive pools.
Topics: Animals; Calcium; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Exocytosis; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Kinetics; Mice; Mice, Inbred BALB C; Protein Kinase C; Tetradecanoylphorbol Acetate | 2003 |
Role of the different mitogen-activated protein kinase subfamilies in the stimulation of dog and human thyroid epithelial cell proliferation by cyclic adenosine 5'-monophosphate and growth factors.
Topics: Animals; Arsenites; Carcinogens; Cell Division; Cells, Cultured; Colforsin; Cyclic AMP; Dogs; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Flavonoids; Hepatocyte Growth Factor; Humans; Hypoglycemic Agents; Imidazoles; Insulin; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sodium Compounds; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 2003 |
Transient agonist-induced regulation of the cholecystokinin-A and cholecystokinin-B receptor mRNA levels in rat pancreatic acinar AR42J cells.
Topics: Animals; Benzodiazepinones; Bucladesine; Cell Line; Colforsin; Dactinomycin; Down-Regulation; Gastrins; Pancreas; Phenylurea Compounds; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; RNA, Messenger; Sincalide; Tetradecanoylphorbol Acetate; Up-Regulation | 2003 |
A chloride channel at the basolateral membrane of the distal-convoluted tubule: a candidate ClC-K channel.
Topics: Animals; Calcium; Cell Membrane; Cells, Cultured; Chloride Channels; Colforsin; Electric Conductivity; Hydrogen-Ion Concentration; Ion Channel Gating; Kidney Tubules, Distal; Male; Membrane Potentials; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate | 2003 |
Real-time imaging of the dynamics and secretory behavior of Weibel-Palade bodies.
Topics: Calcium; Colforsin; Computer Systems; Cyclic AMP; Endothelial Cells; Endothelium, Vascular; Exocytosis; Focal Adhesions; Green Fluorescent Proteins; Humans; Luminescent Proteins; Membrane Fusion; Microscopy, Fluorescence; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Thrombin; von Willebrand Factor; Weibel-Palade Bodies | 2003 |
Protein kinase A and protein kinase C signaling pathway interaction in phenylethanolamine N-methyltransferase gene regulation.
Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activators; Gene Expression Regulation; Immediate-Early Proteins; Macromolecular Substances; PC12 Cells; Phenylethanolamine N-Methyltransferase; Promoter Regions, Genetic; Protein Kinase C; Rats; Receptors, Glucocorticoid; Signal Transduction; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription Factors | 2003 |
Functional characterization of the human phosphodiesterase 7A1 promoter.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Colforsin; CpG Islands; Cyclic AMP Response Element-Binding Protein; Cyclic Nucleotide Phosphodiesterases, Type 7; DNA Footprinting; DNA, Complementary; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate | 2003 |
Regulatory mechanism of Cordyceps sinensis mycelium on mouse Leydig cell steroidogenesis.
Topics: Androstenedione; Animals; Cells, Cultured; Colforsin; Cordyceps; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Hydroxycholesterols; Isoquinolines; Leydig Cells; Male; Mice; Mice, Inbred C57BL; Mycelium; Progestins; Protein Kinase C; Staurosporine; Sulfonamides; Testosterone; Tetradecanoylphorbol Acetate | 2003 |
Glucocorticoids regulate the expression of the mouse urocortin II gene: a putative connection between the corticotropin-releasing factor receptor pathways.
Topics: 5' Flanking Region; Adrenalectomy; Animals; Brain; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cycloheximide; Dexamethasone; Gene Expression Regulation; Glucocorticoids; Half-Life; Hormone Antagonists; Humans; Male; Mice; Mice, Inbred C57BL; Mifepristone; Promoter Regions, Genetic; Receptors, Corticotropin-Releasing Hormone; Receptors, Glucocorticoid; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Urocortins | 2003 |
Caspase-3-dependent reactivation of latent herpes simplex virus type 1 in sensory neuronal cultures.
Topics: Adenoviridae; Animals; Apoptosis; Caspase 3; Caspases; Cells, Cultured; Colforsin; Cysteine Proteinase Inhibitors; Enzyme Activation; Ganglia, Spinal; Genetic Vectors; Herpesvirus 1, Human; Nerve Growth Factors; Nerve Tissue Proteins; Neurons, Afferent; Oligopeptides; Rats; Recombinant Fusion Proteins; Sphingosine; Tetradecanoylphorbol Acetate; Virus Activation; Virus Latency | 2003 |
Phosphorylation of the alpha4 subunit of human alpha4beta2 nicotinic receptors: role of cAMP-dependent protein kinase (PKA) and protein kinase C (PKC).
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bucladesine; Carcinogens; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Humans; Indoles; Isoquinolines; Neurons; Phosphorylation; Protein Kinase C; Receptors, Nicotinic; Sulfonamides; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection | 2003 |
c-Fos is essential for the response of the tyrosine hydroxylase gene to depolarization or phorbol ester.
Topics: Animals; Calcium; Cell Membrane; Clone Cells; Colforsin; Enzyme Induction; Gene Expression Regulation; PC12 Cells; Phorbol Esters; Potassium Chloride; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Rats; RNA, Antisense; Tetradecanoylphorbol Acetate; Transfection; Tyrosine 3-Monooxygenase | 2003 |
Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Cannabinoids; Capsaicin; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Ganglia, Spinal; In Vitro Techniques; Male; Nerve Growth Factor; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2003 |
Regulation of 11beta-hydroxysteroid dehydrogenase type II expression in the renal epithelial cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Activators; Epithelial Cells; Female; Gene Expression Regulation; Kidney; Protein Kinase C; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 2003 |
Striatal proenkephalin gene induction: coordinated regulation by cyclic AMP and calcium pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antihypertensive Agents; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Carcinogens; Cells, Cultured; Colforsin; Corpus Striatum; Cyclic AMP; Drug Interactions; Embryo, Mammalian; Enkephalins; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Humans; Isoquinolines; Neurons; Nifedipine; Protein Precursors; Pyrroles; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection | 2003 |
Regulation of ACTH levels in anterior pituitary cells during stimulated secretion: evidence for aspartyl and cysteine proteases in the cellular metabolism of ACTH.
Topics: Adrenocorticotropic Hormone; Animals; Aspartic Acid Endopeptidases; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Cysteine Endopeptidases; Dexamethasone; Dose-Response Relationship, Drug; Down-Regulation; Pituitary Gland, Anterior; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Up-Regulation | 2003 |
An activator protein 1-like motif mediates 17beta-estradiol repression of gonadotropin-releasing hormone receptor promoter via an estrogen receptor alpha-dependent mechanism in ovarian and breast cancer cells.
Topics: Base Sequence; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Colforsin; DNA, Neoplasm; Estradiol; Estrogen Receptor alpha; Female; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Ovarian Neoplasms; Promoter Regions, Genetic; Receptors, Estrogen; Receptors, LHRH; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic | 2003 |
Parathyroid hormone-related protein(1-34) regulates Phex expression in osteoblasts through the protein kinase A pathway.
Topics: Animals; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Osteoblasts; Parathyroid Hormone-Related Protein; Peptide Fragments; PHEX Phosphate Regulating Neutral Endopeptidase; Protein Kinase C; Proteins; Rats; RNA, Messenger; Skull; Tetradecanoylphorbol Acetate; Up-Regulation | 2003 |
Group II metabotropic glutamate receptor modulation of excitatory transmission in rat subthalamic nucleus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenylyl Cyclase Inhibitors; Amino Acids; Amino Acids, Dicarboxylic; Animals; Colforsin; Cyclopropanes; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Glycine; Imines; In Vitro Techniques; Isoquinolines; Male; Picrotoxin; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Subthalamic Nucleus; Sulfonamides; Synaptic Transmission; Tetradecanoylphorbol Acetate; Xanthenes | 2003 |
Functional expression of the human thiazide-sensitive NaCl cotransporter in Madin-Darby canine kidney cells.
Topics: Aldosterone; Animals; Benzothiadiazines; Carcinogens; Cell Line; Cell Membrane; Colforsin; Diuretics; Dogs; Epithelial Cells; Gene Expression; Glycosylation; Humans; Kidney; Signal Transduction; Sodium; Sodium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Tetradecanoylphorbol Acetate | 2003 |
Cathepsin L gene expression and promoter activation in rodent granulosa cells.
Topics: Animals; Base Sequence; Binding Sites; Breast Neoplasms; Cathepsin L; Cathepsins; Cell Line; Chorionic Gonadotropin; Colforsin; CREB-Binding Protein; Cysteine Endopeptidases; DNA; DNA-Binding Proteins; Drosophila; Female; Gene Deletion; Gene Expression Regulation; Gonadotropins, Equine; Granulosa Cells; Humans; In Situ Hybridization; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Sp1 Transcription Factor; Sp3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2004 |
Exocytosis of a complement component C3-like protein by tunicate hemocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Calcimycin; Carrageenan; Cell Survival; Cholera Toxin; Colchicine; Colforsin; Complement C3; Cytochalasin D; Cytoplasmic Vesicles; Enzyme-Linked Immunosorbent Assay; Exocytosis; Hemocytes; Immunohistochemistry; Kinetics; Lipopolysaccharides; Mannans; Microscopy, Electron; Phenanthridines; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Urochordata | 2004 |
Impact of VIP and cAMP on the regulation of TNF-alpha and IL-10 production: implications for rheumatoid arthritis.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Arthritis, Rheumatoid; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 4; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-10; Ionomycin; Lipopolysaccharides; Macrophages; Monocytes; Phosphodiesterase Inhibitors; Protein Kinase C; Rolipram; Synovial Membrane; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide | 2003 |
Calcitonin in human odontoclasts regulates root resorption activity via protein kinase A.
Topics: Acid Phosphatase; Actins; Bucladesine; Calcitonin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression; Humans; Immunohistochemistry; Isoenzymes; Microscopy, Electron, Scanning; Microscopy, Phase-Contrast; Osteoclasts; Protein Kinase C; Receptors, Calcitonin; Reverse Transcriptase Polymerase Chain Reaction; Root Resorption; Signal Transduction; Tartrate-Resistant Acid Phosphatase; Tetradecanoylphorbol Acetate; Thionucleotides; Tooth, Deciduous | 2004 |
Regulation of the human corticotropin-releasing-hormone gene promoter activity by antidepressant drugs in Neuro-2A and AtT-20 cells.
Topics: Animals; Antidepressive Agents; Cell Differentiation; Cell Line; Cell Survival; Chloramphenicol O-Acetyltransferase; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Glucocorticoids; Humans; Mice; Molecular Biology; Neuroblastoma; Pituitary Gland; Potassium Chloride; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transfection | 2004 |
Small nuclear RING finger protein expression during gonad development: regulation by gonadotropins and estrogen in the postnatal ovary.
Topics: Animals; Chorionic Gonadotropin; Colforsin; Estrogens; Female; Follicle Stimulating Hormone; Gene Expression Regulation; Gestational Age; Gonadotropins; Granulosa Cells; Humans; Luteinizing Hormone; Male; Mice; Nuclear Proteins; Oocytes; Ovarian Follicle; Ovary; Rats; RNA Probes; RNA, Antisense; RNA, Messenger; Testis; Tetradecanoylphorbol Acetate; Transcription Factors; Ubiquitin-Protein Ligases | 2004 |
Inhibitory effects of group II mGluR-related drugs on memory performance in mice.
Topics: Amino Acids; Animals; Anticonvulsants; Avoidance Learning; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclopropanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Isoquinolines; Male; Memory; Mice; Reaction Time; Receptors, Metabotropic Glutamate; Rolipram; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Xanthenes | 2004 |
Pharmacological properties of glycine transport in the frog retina.
Topics: 1-Methyl-3-isobutylxanthine; Amoxapine; Animals; Biological Transport; Colforsin; Glycine; Ranidae; Retina; Sarcosine; Tetradecanoylphorbol Acetate | 2004 |
PGE2 induces IL-1beta gene expression in mouse osteoblasts through a cAMP-PKA signaling pathway.
Topics: Adenylyl Cyclase Inhibitors; Animals; Animals, Newborn; Blotting, Northern; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dinoprostone; Enzyme Inhibitors; Gene Expression; Interleukin-1; Mice; Mice, Inbred BALB C; Osteoblasts; Plasmids; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 2004 |
Mitochondrial alkaline phosphatase as an intracellular signal in the synthesis of 1,25(OH)2D3 and 24,25(OH)2D3 in LLC-PK1 cells.
Topics: 24,25-Dihydroxyvitamin D 3; Alkaline Phosphatase; Animals; Calcifediol; Calcitriol; Colforsin; LLC-PK1 Cells; Mitochondria; Swine; Tetradecanoylphorbol Acetate | 2003 |
Regulation of apical surface fluid and protein secretion in human airway epithelial cell line Calu-3.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anti-Arrhythmia Agents; Body Fluids; Cell Line; Cell Polarity; Colforsin; Cystic Fibrosis Transmembrane Conductance Regulator; Dinoprost; Epithelial Cells; Glyburide; Humans; Muramidase; Oxytocics; Respiratory Mucosa; Stilbenes; Tetradecanoylphorbol Acetate | 2004 |
Activation of protein kinase C antagonizes the opioid inhibition of calcium current in rat spinal dorsal horn neurons.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Colforsin; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Activation; Enzyme Inhibitors; Female; Indoles; Isoquinolines; Male; Maleimides; Membrane Potentials; Narcotics; Patch-Clamp Techniques; Posterior Horn Cells; Potassium Channel Blockers; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetrodotoxin | 2004 |
Activation of second messenger-dependent protein kinases induces muscarinic acetylcholine receptor desensitization in rat thyroid epithelial cells.
Topics: Animals; Arsenicals; Calcium; Calcium Channels; Carbachol; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endocytosis; Epithelial Cells; Indoles; Maleimides; Muscarinic Agonists; Protein Kinase C; Rats; Rats, Inbred F344; Receptors, Muscarinic; Second Messenger Systems; Sucrose; Tetradecanoylphorbol Acetate; Thyroid Gland | 2004 |
Neuronal cell lines transfected with the dopamine D2 receptor gene promoter as a model for studying the effects of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Cell Line, Tumor; Colforsin; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Neuroblastoma; Neurons; Promoter Regions, Genetic; Rats; Receptors, Dopamine D2; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tretinoin | 2004 |
Protein kinase C mediates phosphorylation, desensitization, and trafficking of the D2 dopamine receptor.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; Cell Membrane; Colforsin; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Enzyme Activation; Genes, Dominant; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; Protein Transport; Rats; Receptors, Dopamine D2; Tetradecanoylphorbol Acetate; Transfection | 2004 |
Protein kinase C and epidermal growth factor stimulation of Raf1 potentiates adenylyl cyclase type 6 activation in intact cells.
Topics: Adenylyl Cyclases; Animals; Base Sequence; Cell Line; CHO Cells; Colforsin; Cricetinae; DNA Primers; Enzyme Activation; Epidermal Growth Factor; Humans; Isoproterenol; Kidney; Kinetics; Mutagenesis, Site-Directed; Protein Kinase C; Proto-Oncogene Proteins c-raf; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand.
Topics: 2-Amino-5-phosphonovalerate; Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Casein Kinase II; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Disks Large Homolog 4 Protein; Enzyme Activation; Hippocampus; Humans; Intracellular Signaling Peptides and Proteins; Ligands; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neuronal Plasticity; Phosphorylation; Phosphoserine; Protein Interaction Mapping; Protein Kinase C; Protein Processing, Post-Translational; Protein Structure, Tertiary; Protein Subunits; Protein Transport; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Structure-Activity Relationship; Synapses; Tetradecanoylphorbol Acetate | 2004 |
Adenylyl cyclase-cAMP system inhibits thrombin-induced HSP27 in vascular smooth muscle cells.
Topics: Adenine; Adenylyl Cyclases; Animals; Base Sequence; Cell Line; Colforsin; Cyclic AMP; DNA Primers; Heat-Shock Proteins; Muscle, Smooth, Vascular; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Rats; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 2005 |
Effects of leptin on gonadotropin-releasing hormone release from hypothalamic-infundibular explants and gonadotropin release from adenohypophyseal primary cell cultures: further evidence that fully nourished cattle are resistant to leptin.
Topics: Animals; Cattle; Cells, Cultured; Colforsin; Drug Resistance; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Hypothalamus; Leptin; Luteinizing Hormone; Male; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Tetradecanoylphorbol Acetate | 2005 |
Regulation of thrombomodulin expression in human vascular smooth muscle cells by COX-2-derived prostaglandins.
Topics: Alprostadil; Blood Coagulation; Bucladesine; Carotid Artery Diseases; Carotid Artery, Internal; Cells, Cultured; Colforsin; Coronary Vessels; Culture Media, Serum-Free; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Epoprostenol; Etoricoxib; Gene Expression Profiling; Gene Expression Regulation; Humans; Iloprost; Isoquinolines; Mammary Arteries; Membrane Proteins; Models, Biological; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Receptors, Prostaglandin; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; RNA, Messenger; Saphenous Vein; Second Messenger Systems; Sulfonamides; Sulfones; Tetradecanoylphorbol Acetate; Thrombomodulin; Thrombophilia; Vasodilator Agents | 2005 |
Mitochondrial Ca2+-activated K+ channels in cardiac myocytes: a mechanism of the cardioprotective effect and modulation by protein kinase A.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Benzimidazoles; Carbocyanines; Cell Death; Colforsin; Cyclic AMP-Dependent Protein Kinases; Decanoic Acids; Diazoxide; Fluorescent Dyes; Guinea Pigs; Heart Ventricles; Heterocyclic Compounds, 3-Ring; Hydroxy Acids; Indoles; Intracellular Membranes; Ion Transport; Membrane Potentials; Mitochondria, Heart; Myocytes, Cardiac; Ouabain; Potassium; Potassium Channels, Calcium-Activated; Second Messenger Systems; Tetradecanoylphorbol Acetate | 2005 |
Effects of leptin, acetylcholine and vasoactive intestinal polypeptide on insulin secretion in isolated ob/ob mouse pancreatic islets.
Topics: Acetylcholine; Animals; Caffeine; Cells, Cultured; Colforsin; Female; Insulin; Insulin Secretion; Islets of Langerhans; Leptin; Mice; Mice, Obese; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 2004 |
Isolation of marmoset P450c17 cDNA and gene regulation in vitro.
Topics: Adrenal Cortex; Amino Acid Sequence; Angiotensin II; Animals; Callithrix; Cells, Cultured; Colforsin; DNA, Complementary; Drug Synergism; Gene Expression Regulation; Humans; Hydrocortisone; Macaca mulatta; Molecular Sequence Data; Sequence Homology, Amino Acid; Steroid 17-alpha-Hydroxylase; Tetradecanoylphorbol Acetate | 2004 |
Expression of AT1-R in marmoset whole adrenal glands and adrenocortical cells in culture.
Topics: Adrenal Glands; Angiotensin II; Animals; Callithrix; Cells, Cultured; Colforsin; Drug Combinations; Immunohistochemistry; Macaca mulatta; Male; Receptor, Angiotensin, Type 1; Staining and Labeling; Steroid 17-alpha-Hydroxylase; Tetradecanoylphorbol Acetate; Tissue Distribution; Zona Glomerulosa | 2004 |
Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation.
Topics: Albinism; Animals; Calcium Signaling; Carcinogens; Colforsin; Exocytosis; Glucose; Immunologic Deficiency Syndromes; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mutation; Organ Culture Techniques; Potassium; rab GTP-Binding Proteins; rab27 GTP-Binding Proteins; RNA Splicing; Secretory Vesicles; Tetradecanoylphorbol Acetate | 2005 |
Effect of prostaglandin E2 on PMA-induced macrophage differentiation.
Topics: Cell Adhesion; Cell Differentiation; Colforsin; Dinoprostone; HL-60 Cells; Humans; Macrophages; Matrix Metalloproteinase 9; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2005 |
Luteinizing hormone-induced extracellular-signal regulated kinase activation differently modulates progesterone and androstenedione production in bovine theca cells.
Topics: Androstenedione; Animals; Butadienes; Cattle; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblast Growth Factor 2; Isoquinolines; Luteinizing Hormone; Nitriles; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Progesterone; Protein Kinase Inhibitors; RNA, Messenger; Steroid 17-alpha-Hydroxylase; Sulfonamides; Tetradecanoylphorbol Acetate; Theca Cells | 2005 |
Optimization of gene transfer into neonatal rat cardiomyocytes and unmasking of cytomegalovirus promoter silencing.
Topics: Adenoviridae; Animals; Animals, Newborn; Avian Sarcoma Viruses; beta-Galactosidase; Cells, Cultured; Colforsin; Cytomegalovirus; DNA-Binding Proteins; Gene Expression; Gene Silencing; Luciferases; MEF2 Transcription Factors; Myocytes, Cardiac; Myogenic Regulatory Factors; Plasmids; Polylysine; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 2005 |
SOST is a target gene for PTH in bone.
Topics: Adaptor Proteins, Signal Transducing; Animals; Bone Density; Bone Morphogenetic Proteins; Cell Line; Colforsin; Cyclic AMP; Cycloheximide; Female; Femur; Genetic Markers; Glycoproteins; Intercellular Signaling Peptides and Proteins; Ionomycin; Mice; Osteogenesis; Ovariectomy; Parathyroid Hormone; Peptide Fragments; Protein Synthesis Inhibitors; Rats; Rats, Wistar; RNA Stability; RNA, Messenger; Skull; Tetradecanoylphorbol Acetate; Tissue Culture Techniques | 2005 |
Protein kinases influence bovine oocyte competence during short-term treatment with recombinant human follicle stimulating hormone.
Topics: Adenylyl Cyclases; Animals; Cattle; Cell Survival; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activators; Enzyme Inhibitors; Fertilization in Vitro; Follicle Stimulating Hormone; Humans; Oocytes; Oogenesis; Protein Kinase C; Protein Kinases; Recombinant Proteins; Sphingosine; Tetradecanoylphorbol Acetate; Thionucleotides; Time Factors | 2005 |
Glucose represses connexin36 in insulin-secreting cells.
Topics: Animals; Base Sequence; Cell Line, Tumor; Colforsin; Connexins; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Down-Regulation; Flavonoids; Gap Junction delta-2 Protein; Glucose; Humans; Insulin-Secreting Cells; Isoquinolines; Mitogen-Activated Protein Kinases; Nifedipine; Promoter Regions, Genetic; Rats; Response Elements; RNA, Messenger; Sequence Deletion; Sulfonamides; Tetradecanoylphorbol Acetate | 2005 |
HMGB1 expression and release by bone cells.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Bone and Bones; Bone Marrow Cells; Cell Line; Cell Line, Tumor; Cell Nucleus; Colforsin; Dose-Response Relationship, Drug; HMGB1 Protein; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteosarcoma; Parathyroid Hormone; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 2006 |
Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation.
Topics: Adenosine Triphosphatases; Alanine; Animals; Calsequestrin; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP-Dependent Protein Kinases; Glutamic Acid; Humans; Immunoblotting; Ions; Membrane Proteins; Mice; Mice, Knockout; Muscle Cells; Muscles; Mutation; Myocardium; Phosphoproteins; Phosphorylation; Serine; Sodium; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Differentiation of human bone marrow stem cells into cells with a neural phenotype: diverse effects of two specific treatments.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Antigens, CD; Blotting, Western; Bone Marrow Cells; Cell Differentiation; Cell Size; Cells, Cultured; Child; Colforsin; Fibroblast Growth Factor 1; Flow Cytometry; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Humans; Immunohistochemistry; Intermediate Filament Proteins; Mercaptoethanol; Microscopy, Electron, Scanning; Nerve Tissue Proteins; Nestin; Neurofilament Proteins; Neurons; Phenotype; Phosphodiesterase Inhibitors; Phosphopyruvate Hydratase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 2006 |
Parathyroid hormone regulates osterix and Runx2 mRNA expression predominantly through protein kinase A signaling in osteoblast-like cells.
Topics: Alkaline Phosphatase; Animals; Cell Line, Tumor; Colforsin; Core Binding Factor Alpha 1 Subunit; Cyclic AMP-Dependent Protein Kinases; Enzyme Activators; Humans; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors | 2006 |
Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic beta-cell glucose metabolism and insulin secretion.
Topics: Alanine; Arginine; Calcium; Carbachol; Clone Cells; Colforsin; Culture Media; Dose-Response Relationship, Drug; Gastrointestinal Hormones; Glucose; Homocysteine; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Keto Acids; Metabolic Syndrome; Potassium Chloride; Tetradecanoylphorbol Acetate; Tolbutamide | 2006 |
Human astrocytes can be induced to differentiate into cells with neuronal phenotype.
Topics: 1-Methyl-3-isobutylxanthine; Astrocytes; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Brain; Cell Differentiation; Cell Proliferation; Cells, Cultured; Colforsin; Fetus; Fibroblast Growth Factor 1; Gene Expression; Glial Fibrillary Acidic Protein; Homeodomain Proteins; Humans; Intermediate Filament Proteins; Membrane Potentials; Nerve Tissue Proteins; Nestin; Neurofilament Proteins; Neurons; Phosphopyruvate Hydratase; RNA, Messenger; Synaptophysin; Tetradecanoylphorbol Acetate; Transcription Factor HES-1; Tubulin | 2006 |
Phosphorylation of endothelin converting enzyme-1 isoforms: relevance to subcellular localization.
Topics: Animals; Aspartic Acid Endopeptidases; Cell Compartmentation; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Dose-Response Relationship, Drug; Endothelin-Converting Enzymes; Enzyme Inhibitors; Glucose; Green Fluorescent Proteins; Immunohistochemistry; Isoenzymes; Metalloendopeptidases; Phosphorylation; Recombinant Fusion Proteins; Subcellular Fractions; Tetradecanoylphorbol Acetate | 2006 |
Circadian rhythm generation in a glioma cell line.
Topics: Animals; Cell Cycle Proteins; Cell Line, Tumor; Chlorocebus aethiops; Circadian Rhythm; Colforsin; COS Cells; Dexamethasone; Glioma; Horses; Humans; Ionomycin; Luminescence; Mice; Nuclear Proteins; Period Circadian Proteins; Promoter Regions, Genetic; Rats; Tetradecanoylphorbol Acetate; Transcription Factors; Up-Regulation | 2006 |
Expression and regulation of the mu opioid peptide receptor in TPA-differentiated HL-60 promyelocytic leukemia cells.
Topics: Analgesics, Opioid; Colforsin; Cyclic AMP; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Morphine; Naloxone; Narcotic Antagonists; NF-kappa B; Protein Binding; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2006 |
Identification, regulation and anti-proliferative role of the NPR-C receptor in gastric epithelial cells.
Topics: Adenylyl Cyclases; Animals; Atrial Natriuretic Factor; Cell Proliferation; Colforsin; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Fluorescent Antibody Technique; Gastric Mucosa; Male; Protein Kinases; Rats; Rats, Wistar; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2006 |
Characterization of mechanisms involved in secretion of active heparanase.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cell Line; Cell Movement; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Glucuronidase; HCT116 Cells; HT29 Cells; Humans; Lysosomes; Protein Kinase C; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 2006 |
Role of kinases and G-proteins in the hyposmotic stimulation of cardiac IKs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Chromans; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cytochalasin D; Cytoskeleton; GTP-Binding Proteins; Guinea Pigs; Indoles; Isoquinolines; KCNQ1 Potassium Channel; Maleimides; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Osmotic Pressure; Phosphatidylinositol 3-Kinases; Potassium Channels; Protein Kinase C; Protein-Tyrosine Kinases; Sulfonamides; Tetradecanoylphorbol Acetate; Tyrphostins | 2006 |
Protein kinase C cross-talk with gonadotrope progesterone receptor is involved in GnRH-induced LH secretion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bodily Secretions; Cells, Cultured; Chelating Agents; Colforsin; Egtazic Acid; Enzyme Inhibitors; Female; Gonadotropin-Releasing Hormone; Imines; Indoles; Ionomycin; Luteinizing Hormone; Maleimides; Mifepristone; Nifedipine; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Receptors, Progesterone; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Up-regulation of endogenous RGS2 mediates cross-desensitization between Gs and Gq signaling in osteoblasts.
Topics: Adenosine Triphosphate; Adenoviridae; Animals; Cell Culture Techniques; Cells, Cultured; Colforsin; Fluorescent Antibody Technique, Indirect; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Osteoblasts; Parathyroid Hormone; Peptide Fragments; RGS Proteins; Signal Transduction; Skull; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Differential responses of corticotropin-releasing hormone receptor type 1 variants to protein kinase C phosphorylation.
Topics: Animals; Arrestin; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gs; Humans; Phosphorylation; Protein Kinase C; Rats; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Actions of glucagon-like peptide-1 on KATP channel-dependent and -independent effects of glucose, sulphonylureas and nateglinide.
Topics: Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclohexanes; Dose-Response Relationship, Drug; Glucagon-Like Peptide 1; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Nateglinide; Phenylalanine; Potassium Channels; Protein Kinase C; Stimulation, Chemical; Sulfonylurea Compounds; Tetradecanoylphorbol Acetate | 2006 |
Resveratrol inhibits insulin secretion from rat pancreatic islets.
Topics: Animals; Colforsin; Dose-Response Relationship, Drug; Glucose; Glutamine; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Phytoalexins; Rats; Rats, Wistar; Resveratrol; Sesquiterpenes; Stilbenes; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 2006 |
Homocysteine-induced impairment of insulin secretion from clonal pancreatic BRIN-BD11 beta-cells is not prevented by catalase.
Topics: Amino Acids; Animals; Calcium; Carcinogens; Catalase; Cell Line; Clone Cells; Colforsin; Dose-Response Relationship, Drug; Glucose; Homocysteine; Hydrogen Peroxide; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Keto Acids; Oxidation-Reduction; Potassium Chloride; Rats; Tetradecanoylphorbol Acetate; Tolbutamide | 2007 |
Regulation of matrix Gla protein by parathyroid hormone in MC3T3-E1 osteoblast-like cells involves protein kinase A and extracellular signal-regulated kinase pathways.
Topics: 3T3 Cells; Animals; Butadienes; Calcium-Binding Proteins; Colforsin; Cyclic AMP-Dependent Protein Kinases; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Indoles; Isoquinolines; Maleimides; Matrix Gla Protein; Mice; Nitriles; Osteoblasts; Parathyroid Hormone; Promoter Regions, Genetic; Protein Kinase C; Recombinant Proteins; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate | 2007 |
Chronic gonadotropin-releasing hormone inhibits activin induction of the ovine follicle-stimulating hormone beta-subunit: involvement of 3',5'-cyclic adenosine monophosphate response element binding protein and nitric oxide synthase type I.
Topics: Activins; Animals; Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone, beta Subunit; Follistatin; Gene Expression; Gonadotropin-Releasing Hormone; Humans; Luciferases; Male; Mice; Mice, Transgenic; Nitric Oxide Synthase Type I; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Time Factors | 2007 |
Regulation of plasminogen activators in human thyroid follicular cells and their relationship to differentiated function.
Topics: Adenylyl Cyclases; Aprotinin; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activators; Epidermal Growth Factor; Fibroblast Growth Factors; Flavonoids; Humans; Indoles; Insulin; Iodine; Iodine Radioisotopes; Maleimides; Mesylates; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Plasminogen Inactivators; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; RNA, Messenger; Serine Proteinase Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2007 |
Regulation of the Na+/Ca2+ exchanger (NCX) in the murine embryonic heart.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Carbazoles; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Fetal Development; Gestational Age; Heart; Heart Ventricles; Indoles; Mice; Myocytes, Cardiac; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Pyrroles; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate | 2007 |
Resveratrol-induced inhibition of insulin secretion from rat pancreatic islets: evidence for pivotal role of metabolic disturbances.
Topics: Animals; Carrier Proteins; Cell Survival; Colforsin; Estradiol; Fulvestrant; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Membrane Potential, Mitochondrial; Metabolic Networks and Pathways; Rats; Rats, Wistar; Receptors, Estrogen; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2007 |
Sensitization to heat through G-protein-coupled receptor pathways in the isolated sciatic mouse nerve.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Colforsin; Dinoprostone; Hot Temperature; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxytocics; Receptors, G-Protein-Coupled; Sciatic Nerve; Signal Transduction; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2007 |
Lipofection of insulin-producing RINm5F cells: methodological improvements.
Topics: Animals; Carcinogens; Cell Death; Cell Line; Colforsin; Enzyme Inhibitors; Fumonisins; Gene Expression; Genetic Vectors; Green Fluorescent Proteins; Insulin; Insulin Secretion; Lipids; Rats; Tetradecanoylphorbol Acetate; Transfection | 2007 |
Control of cyclic AMP concentration in bovine endometrial stromal cells by arachidonic acid.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclase Inhibitors; Animals; Arachidonic Acid; Cattle; Cells, Cultured; Colforsin; Cyclic AMP; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Endometrium; Female; Indoles; Maleimides; Paracrine Communication; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase C; Stromal Cells; Tetradecanoylphorbol Acetate | 2007 |
Regulation of C/EBPbeta mRNA expression and C/EBPbeta promoter activity by protein kinases A and C in a myelomonocytic cell line (HD11).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; CCAAT-Enhancer-Binding Protein-beta; Cell Line; Chickens; Colforsin; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Humans; Mice; Molecular Sequence Data; Monocytes; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Protein Kinase C; RNA Stability; RNA, Messenger; Sequence Alignment; Signal Transduction; Tetradecanoylphorbol Acetate | 2007 |
Prostanoids induce egr1 gene expression in cementoblastic OCCM cells.
Topics: Animals; Blotting, Northern; Blotting, Western; Carcinogens; Cell Line; Colforsin; Dental Cementum; Dinoprost; Dinoprostone; Early Growth Response Protein 1; Enzyme Activators; Gene Expression Regulation; Ionomycin; Ionophores; Mice; Prostaglandins; Prostaglandins F, Synthetic; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Zinc Fingers | 2007 |
Induction of translationally controlled tumor protein (TCTP) by transcriptional and post-transcriptional mechanisms.
Topics: 3' Flanking Region; Animals; Binding Sites; Biomarkers, Tumor; Blotting, Northern; Blotting, Western; Cells, Cultured; Chlorocebus aethiops; Cobalt; Colforsin; Copper; COS Cells; Dioxins; Humans; Luciferases; Nickel; Promoter Regions, Genetic; Protein Biosynthesis; Response Elements; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Tumor Protein, Translationally-Controlled 1 | 2007 |
Regulation of activin receptor-interacting protein 2 expression in mouse hepatoma Hepa1-6 cells and its relationship with collagen type IV.
Topics: Activin Receptors, Type II; Activins; Adaptor Proteins, Signal Transducing; Adenylyl Cyclases; Animals; Calcimycin; Calcium; Carcinoma, Hepatocellular; Cell Line, Tumor; Colforsin; Collagen Type IV; Enzyme Activators; Gene Expression Regulation, Neoplastic; Ionophores; Kinetics; Lipopolysaccharides; Liver Neoplasms; Membrane Proteins; Mice; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 2007 |
Regulation of protein kinase D activity in adult myocardium: novel counter-regulatory roles for protein kinase Cepsilon and protein kinase A.
Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Heart Ventricles; Isoproterenol; Isoquinolines; Male; Mice; Myocardium; Myocytes, Cardiac; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate; Troponin I | 2007 |
Endothelin potentiates TRPV1 via ETA receptor-mediated activation of protein kinase C.
Topics: Animals; Capsaicin; Cell Line; Cells, Cultured; Colforsin; Cyclic AMP; Endothelin-1; Enzyme Activation; Fluorescent Antibody Technique; Ganglia, Spinal; Humans; Inositol Phosphates; Male; Membrane Potentials; Mutation; Neurons; Patch-Clamp Techniques; Protein Kinase C; Radioligand Assay; Rats; Rats, Wistar; Receptor, Endothelin A; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2007 |
Peroxisome proliferator-activated receptor gamma is a target of progesterone regulation in the preovulatory follicles and controls ovulation in mice.
Topics: Anilides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Colforsin; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Female; Gene Deletion; Gene Expression Profiling; Gonadotropins; Granulosa Cells; Hormone Antagonists; Immunohistochemistry; In Situ Hybridization; Indomethacin; Mice; Mice, Knockout; Mifepristone; Models, Genetic; Nitrobenzenes; Ovarian Follicle; Ovary; Ovulation; PPAR gamma; Progesterone; Receptors, Progesterone; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors | 2008 |
Characterisation of aromatase expression in the human adipocyte cell line SGBS.
Topics: Adipocytes; Adipose Tissue; Aromatase; Cell Line; Colforsin; Cytochrome P-450 Enzyme System; Disease Progression; DNA, Complementary; Estrogens; Humans; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 2008 |
Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Calcium; Cannabinoid Receptor Modulators; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Egtazic Acid; Endocannabinoids; Ganglia, Spinal; Glycerides; Humans; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Proteinase-Activated; Sensory Receptor Cells; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin | 2008 |
Peroxiredoxin 2 is involved in the neuroprotective effects of PACAP in cultured cerebellar granule neurons.
Topics: Amino Acid Sequence; Animals; Caspase 3; Cells, Cultured; Cerebellum; Colforsin; Ethanol; Molecular Sequence Data; Neurons; Neuroprotective Agents; Peroxiredoxins; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Wistar; RNA, Small Interfering; Tetradecanoylphorbol Acetate | 2008 |
Evaluation of adjuvant activities using human antigen presenting cells in vitro.
Topics: Adjuvants, Immunologic; Cell Line, Tumor; Colforsin; Cyclic AMP; Dendritic Cells; Humans; In Vitro Techniques; Lymphocyte Activation; Tetradecanoylphorbol Acetate; Th1 Cells | 2008 |
K+ channels and the cAMP-PKA pathway modulate TGF-beta1-induced migration of rat vascular myofibroblasts.
Topics: Animals; Cell Movement; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Fibroblasts; Male; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1 | 2008 |
Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus.
Topics: Animals; Biological Transport; Choroid Plexus; Colforsin; Cyclic AMP-Dependent Protein Kinases; Estrone; Female; In Vitro Techniques; Kinetics; Leukotriene C4; Male; Meglumine; Methotrexate; Models, Biological; Organic Anion Transporters; p-Aminohippuric Acid; Potassium; Propionates; Protein Kinase C; Quinolines; Rats; Rats, Sprague-Dawley; Sodium Cyanide; Squalus acanthias; Taurocholic Acid; Tetradecanoylphorbol Acetate; Xanthenes | 2008 |
Identification of ERK and JNK as signaling mediators on protein kinase C activation in cultured granulosa cells.
Topics: Animals; Cell Line; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Colforsin; Enzyme Activation; Enzyme Induction; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Granulosa Cells; Humans; Insulin-Like Growth Factor I; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Ribosomal Protein S6 Kinases, 90-kDa; Swine; Tetradecanoylphorbol Acetate | 2008 |
Tamoxifen does not inhibit the swell activated chloride channel in human neutrophils during the respiratory burst.
Topics: Cells, Cultured; Chloride Channels; Colforsin; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phloretin; Respiratory Burst; Superoxides; Tamoxifen; Tetradecanoylphorbol Acetate; Trialkyltin Compounds | 2008 |
Dual effect of ATP on glucose-induced insulin secretion in HIT-T15 cells.
Topics: Adenosine Triphosphate; Animals; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activators; Feedback, Physiological; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Protein Kinase C; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Suramin; Tetradecanoylphorbol Acetate; Thionucleotides | 2008 |
Concomitant activation of adenylyl cyclase suppresses the opposite influences of CB(1) cannabinoid receptor agonists on tyrosine hydroxylase expression.
Topics: Adenylyl Cyclases; Animals; Cannabinoid Receptor Modulators; Cannabinoids; Cell Line, Tumor; Colforsin; Cyclohexanols; DNA Primers; Dronabinol; Enzyme Activation; Excitatory Amino Acid Antagonists; Genes, Reporter; Luciferases; Mice; Neuroblastoma; Pertussis Toxin; Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tyrosine 3-Monooxygenase | 2009 |
Regulatory mechanisms in the differential expression of Hemokinin-1.
Topics: Animals; Base Sequence; Carcinogens; Cell Line; Colforsin; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; Genes, Reporter; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; NF-kappa B; Promoter Regions, Genetic; Rats; Substance P; Tachykinins; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2009 |
Role of PDK1 in regulation of gastric acid secretion.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Carbachol; Colforsin; Extracellular Space; Gastric Acid; Hydrogen-Ion Concentration; Isoquinolines; Mice; Omeprazole; Parietal Cells, Gastric; Potassium; Protein Serine-Threonine Kinases; Quaternary Ammonium Compounds; Sulfonamides; Tetradecanoylphorbol Acetate | 2008 |
Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.
Topics: Animals; Carcinogens; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP-Dependent Protein Kinases; Dual Oxidases; Enzyme Activation; Humans; Hydrogen Peroxide; Iodides; Membrane Proteins; Mutation; NADPH Oxidases; Phosphorylation; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Diseases; Thyroid Gland; Thyroid Hormones | 2009 |
Bradykinin inhibits the transient outward K+ current in mouse Schwann cells via the cAMP/PKA pathway.
Topics: Adamantane; Animals; Benzenesulfonates; Bradykinin; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic CMP; Enzyme Activators; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Guanosine 5'-O-(3-Thiotriphosphate); Isoquinolines; Membrane Potentials; Mice; Mice, Inbred ICR; Potassium; Potassium Channels, Voltage-Gated; Protein Kinase C; Protein Kinase Inhibitors; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Schwann Cells; Sciatic Nerve; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
Site specificity of agonist and second messenger-activated kinases for somatostatin receptor subtype 2A (Sst2A) phosphorylation.
Topics: Animals; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP-Dependent Protein Kinases; Enzyme-Linked Immunosorbent Assay; G-Protein-Coupled Receptor Kinase 2; Humans; Phosphorylation; Protein Kinase C; Receptors, Somatostatin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2009 |
Subcellular localization of cyclic AMP-responsive element binding protein-regulated transcription coactivator 2 provides a link between obesity and breast cancer in postmenopausal women.
Topics: Aromatase; Breast Neoplasms; Colforsin; DNA Primers; Estradiol; Estrogens; Female; Genes, Reporter; Homeostasis; Humans; Leptin; Mammaplasty; Obesity; Polymerase Chain Reaction; Postmenopause; Restriction Mapping; Stromal Cells; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection | 2009 |
Inhibitory effect of the alkaloid warifteine purified from Cissampelos sympodialis on B lymphocyte function in vitro and in vivo.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcimycin; Cell Culture Techniques; Cell Proliferation; Cissampelos; Colforsin; Cyclic AMP; Extracellular Signal-Regulated MAP Kinases; Ficoll; Immunoglobulins; Immunologic Factors; Ionophores; Ligands; Lipopolysaccharides; Mice; Mice, Inbred BALB C; NF-kappa B; Phosphorylation; Plant Extracts; Plant Leaves; Signal Transduction; Spleen; Tetradecanoylphorbol Acetate; Toll-Like Receptors; Trinitrobenzenes | 2010 |
The identification of inhibitors of Schistosoma mansoni miracidial transformation by incorporating a medium-throughput small-molecule screen.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anthelmintics; Benzophenanthridines; Calcimycin; Calcium Channel Blockers; Citalopram; Clomipramine; Colforsin; Cyclic AMP; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Immunohistochemistry; Mice; Schistosoma mansoni; Tetradecanoylphorbol Acetate; Triflupromazine | 2010 |
Involvement of transducer of regulated cAMP response element-binding protein activity on corticotropin releasing hormone transcription.
Topics: Animals; Cell Line; Cell Nucleus; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP Response Element-Binding Protein; Genes, Reporter; Hypothalamus; Promoter Regions, Genetic; Rats; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcriptional Activation | 2010 |
Isoproterenol and cAMP block ERK phosphorylation and enhance [Ca2+]i increases and oxygen consumption by muscarinic receptor stimulation in rat parotid and submandibular acinar cells.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Carbachol; Carcinogens; Cell Line, Transformed; Cell Line, Tumor; Cholinergic Agonists; Colforsin; Cyclic AMP; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Guanine Nucleotide Exchange Factors; Isoproterenol; Male; Oxygen Consumption; Parotid Gland; Phosphorylation; Protein Kinase C; raf Kinases; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Second Messenger Systems; Submandibular Gland; Tetradecanoylphorbol Acetate | 2010 |
Metformin inhibits aromatase expression in human breast adipose stromal cells via stimulation of AMP-activated protein kinase.
Topics: Active Transport, Cell Nucleus; Adipose Tissue; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Aromatase; Aromatase Inhibitors; Binding Sites; Breast; Chlorocebus aethiops; Colforsin; COS Cells; Dose-Response Relationship, Drug; Enzyme Activation; Female; Humans; Metformin; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Stromal Cells; Tetradecanoylphorbol Acetate; Threonine; Transcription Factors; Transfection | 2010 |
Follicle-stimulating hormone promotes proliferation of cultured chicken ovarian germ cells through protein kinases A and C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Proliferation; Cells, Cultured; Chickens; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Follicle Stimulating Hormone; Isoquinolines; Ovum; Protein Kinase C; Receptors, FSH; Sulfonamides; Tetradecanoylphorbol Acetate | 2010 |
Inhibition of ATP release from erythrocytes: a role for EPACs and PKC.
Topics: Adenine; Adenosine Triphosphate; Cilostazol; Colforsin; Cyclic AMP; Enzyme Activation; Erythrocytes; Guanine Nucleotide Exchange Factors; Humans; Iloprost; In Vitro Techniques; Isoproterenol; Models, Biological; Naphthalenes; Phosphodiesterase Inhibitors; Protein Kinase C; Rolipram; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrazoles; Thionucleotides | 2011 |
Tissue-specific regulation of aromatase promoter II by the orphan nuclear receptor LRH-1 in breast adipose stromal fibroblasts.
Topics: Adipose Tissue; Aromatase; Breast; Breast Neoplasms; Chromatin Immunoprecipitation; Colforsin; Dinoprostone; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Organ Specificity; Postmenopause; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering; Stromal Cells; Tetradecanoylphorbol Acetate; Transfection | 2011 |
Novel phosphorylation of aquaporin-5 at its threonine 259 through cAMP signaling in salivary gland cells.
Topics: Amino Acid Substitution; Animals; Antibodies; Antibody Specificity; Aquaporin 5; Calcimycin; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Detergents; Humans; Isoproterenol; Isoquinolines; Male; Mice; Mice, Inbred ICR; Parotid Gland; Phosphorylation; Pilocarpine; Protein Kinase Inhibitors; Protein Transport; Salivary Glands; Signal Transduction; Submandibular Gland; Sulfonamides; Tetradecanoylphorbol Acetate; Threonine; Transfection | 2011 |
The activation state of the inositol 1,4,5-trisphosphate receptor regulates the velocity of intracellular Ca2+ waves in bovine aortic endothelial cells.
Topics: Adenosine Triphosphate; Animals; Aorta; Calcium; Calcium Signaling; Cattle; Cells, Cultured; Colforsin; Endothelium, Vascular; Inositol 1,4,5-Trisphosphate Receptors; Protein Kinases; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2011 |
The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner.
Topics: Adenylyl Cyclases; Amino Acid Motifs; Colforsin; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Enzyme Activators; HEK293 Cells; Humans; Indoles; Isoenzymes; Maleimides; Phosphorylation; Protein Conformation; Protein Kinase C; Receptors, Dopamine D1; Receptors, Dopamine D5; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate | 2012 |
Homologous and heterologous in vitro regulation of pituitary receptors for somatostatin, growth hormone (GH)-releasing hormone, and ghrelin in a nonhuman primate (Papio anubis).
Topics: Animals; Cells, Cultured; Colforsin; Gene Expression; Ghrelin; Growth Hormone-Releasing Hormone; In Vitro Techniques; Papio anubis; Pituitary Gland; Receptors, Ghrelin; Receptors, LHRH; Receptors, Somatostatin; RNA, Messenger; Signal Transduction; Somatostatin; Swine; Tetradecanoylphorbol Acetate | 2012 |
Phospholipase C-related but catalytically inactive protein (PRIP) modulates synaptosomal-associated protein 25 (SNAP-25) phosphorylation and exocytosis.
Topics: Amino Acid Substitution; Animals; Carcinogens; Colforsin; Exocytosis; Mutation, Missense; Norepinephrine; Nuclear Receptor Coactivators; PC12 Cells; Phosphorylation; Protein Phosphatase 1; Rats; Synaptosomal-Associated Protein 25; Tetradecanoylphorbol Acetate | 2012 |
Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3.
Topics: Adenylyl Cyclases; Agouti Signaling Protein; alpha-MSH; Arrestins; beta-Arrestin 1; beta-Arrestins; beta-Defensins; Cells, Cultured; Colforsin; G-Protein-Coupled Receptor Kinases; Humans; Melanocortins; Melanocytes; Monophenol Monooxygenase; Protein Kinase C; Receptor, Melanocortin, Type 1; Skin Pigmentation; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2012 |
Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Ganglia, Spinal; Indoles; Inflammation; Male; Maleimides; MAP Kinase Signaling System; Membrane Potentials; Neurons; Pain; Phosphorylation; Protein Kinase C; Protein Transport; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, Purinergic P2X3; Tetradecanoylphorbol Acetate | 2012 |
Glucose responsiveness in a novel adult-derived GnRH cell line, mHypoA-GnRH/GFP: involvement of AMP-activated protein kinase.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Glucose; Gonadotropin-Releasing Hormone; Green Fluorescent Proteins; Mice; Models, Biological; Neurons; Nitric Oxide; Peptides; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fos; RNA, Messenger; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate | 2013 |
Trophoblast cell fusion and differentiation are mediated by both the protein kinase C and a pathways.
Topics: Cell Differentiation; Cell Fusion; Cell Line; Chorionic Gonadotropin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dysferlin; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Membrane Proteins; Muscle Proteins; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Trophoblasts | 2013 |
Stimulation of corticotropin-releasing factor gene expression by FosB in rat hypothalamic 4B cells.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Enzyme Activators; Gene Expression; Hypothalamus; Neuroendocrine Cells; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2014 |
Modulation of HERG K+ channels by chronic exposure to activators and inhibitors of PKA and PKC: actions independent of PKA and PKC phosphorylation.
Topics: Colforsin; Cyclic AMP-Dependent Protein Kinases; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Indoles; Isoquinolines; Maleimides; Membrane Potential, Mitochondrial; Metalloporphyrins; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; Sulfonamides; Tetradecanoylphorbol Acetate | 2013 |
Modulation of transglutaminase 2 activity in H9c2 cells by PKC and PKA signalling: a role for transglutaminase 2 in cytoprotection.
Topics: Animals; Carbazoles; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoprotection; GTP-Binding Proteins; Indoles; Protein Glutamine gamma Glutamyltransferase 2; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Transglutaminases | 2014 |
Dexmedetomidine suppresses interleukin-1β-induced interleukin-6 synthesis in rat glial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line, Tumor; Colforsin; Dexmedetomidine; Gene Expression Regulation; I-kappa B Kinase; Interleukin-1beta; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Neuroglia; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Receptors, Adrenergic, alpha-2; RNA, Messenger; Tetradecanoylphorbol Acetate; Yohimbine | 2014 |
High-throughput screening identifies compounds that enhance lentiviral transduction.
Topics: Animals; Antigens, CD34; Camptothecin; Cell Line, Tumor; Colforsin; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; HEK293 Cells; Hematopoietic Stem Cells; High-Throughput Screening Assays; Humans; Lentivirus; Mice; NIH 3T3 Cells; Sirolimus; Tetradecanoylphorbol Acetate; Transduction, Genetic; U937 Cells | 2014 |
Corticotropin (ACTH) regulates alternative RNA splicing in Y1 mouse adrenocortical tumor cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Alternative Splicing; Animals; Base Sequence; Cell Line, Tumor; Colforsin; Exons; Humans; Mice; Molecular Sequence Data; RNA, Messenger; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate | 2015 |
Using constitutive activity to define appropriate high-throughput screening assays for orphan g protein-coupled receptors.
Topics: Animals; beta-Galactosidase; Cell Cycle; Colforsin; Cyclin-Dependent Kinase Inhibitor Proteins; Gene Expression Regulation, Fungal; Genes, Reporter; GTP-Binding Protein alpha Subunits, Gq-G11; HEK293 Cells; High-Throughput Screening Assays; Humans; Ionomycin; Ligands; Luciferases; Plasmids; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tetradecanoylphorbol Acetate; Transfection | 2015 |
Swelling-activated and arachidonic acid-induced currents are TREK-1 in rat bladder smooth muscle cells.
Topics: Animals; Arachidonic Acid; Colforsin; Hydrogen-Ion Concentration; Male; Membrane Potentials; Muscle, Smooth; Potassium Channels, Tandem Pore Domain; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Urinary Bladder | 2016 |
Activation of MEK/ERK Signaling by PACAP in Guinea Pig Cardiac Neurons.
Topics: Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Female; Guinea Pigs; Male; MAP Kinase Signaling System; Myocardium; Neurons; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase Inhibitors; Receptors, Vasoactive Intestinal Peptide, Type II; Receptors, Vasoactive Intestinal Polypeptide, Type I; Tetradecanoylphorbol Acetate | 2016 |
Heterologous, PKC-Mediated Desensitization of Human Histamine H3 Receptors Expressed in CHO-K1 Cells.
Topics: Adenosine Triphosphate; Animals; Carbazoles; Cell Membrane; CHO Cells; Colforsin; Cricetulus; Humans; Indoles; Phosphorylation; Protein Kinase C; Receptors, Histamine H3; Signal Transduction; Tetradecanoylphorbol Acetate | 2016 |
Characterization of Na+-K+-2Cl- Cotransporter Activity in Rabbit Lacrimal Gland Duct Cells.
Topics: Analysis of Variance; Animals; Carbachol; Carcinogens; Colforsin; Cyclic GMP; Dry Eye Syndromes; Hydrogen-Ion Concentration; In Vitro Techniques; Lacrimal Apparatus; Male; Ophthalmic Solutions; Osmolar Concentration; Rabbits; Solute Carrier Family 12, Member 2; Tears; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 2016 |
Tetanic Facilitation of Neuromuscular Transmission by Adenosine A2A and Muscarinic M1 Receptors is Dependent on the Uptake of Choline via High-Affinity Transporters.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adenosine; Animals; Colforsin; Diaphragm; Hemicholinium 3; Membrane Transport Proteins; Neostigmine; Phenethylamines; Phrenic Nerve; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptor, Muscarinic M1; Refractory Period, Electrophysiological; Synaptic Transmission; Tetanus; Tetradecanoylphorbol Acetate | 2019 |