tetradecanoylphorbol acetate has been researched along with calpain in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (13.56) | 18.7374 |
| 1990's | 32 (54.24) | 18.2507 |
| 2000's | 17 (28.81) | 29.6817 |
| 2010's | 2 (3.39) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bultel, S; Ducastaing, A; Letard, P; Savart, M | 1 |
| Kawashima, S; Mori, M; Mori, S; Morishita, Y; Nakamura, M | 1 |
| Hata, A; Ohno, S; Suzuki, K | 1 |
| Konno, Y; Mizuno, K; Ohno, S; Osada, S; Saido, TC; Suzuki, K | 1 |
| Brahmi, Z; Shenoy, AM | 1 |
| Kakkar, VV; Krishnamurthi, S; Patel, Y; Sadowska, K; Wheeler-Jones, CP | 1 |
| Kishimoto, A | 1 |
| Adachi, Y; Hatanaka, M; Ishii, K; Maki, M; Murachi, T | 1 |
| Horecker, BL; Melloni, E; Michetti, M; Pontremoli, S; Salamino, F; Sparatore, B | 1 |
| Ishida, E; Ito, M; Sato, A; Shigeta, S; Takami, Y; Tanabe, F | 1 |
| Horecker, BL; Melloni, E; Michetti, M; Patrone, M; Pontremoli, S; Salamino, F | 1 |
| Ferrell, JE; Martin, GS | 1 |
| Melloni, E; Pontremoli, S | 1 |
| Damiani, G; Horecker, BL; Melloni, E; Michetti, M; Pontremoli, S; Salamino, F; Sparatore, B | 1 |
| Horecker, BL; Melloni, E; Michetti, M; Pontremoli, S; Sacco, O; Sparatore, B | 1 |
| Brown, G; Gordon, J; Guy, GR; Michell, RH; Walker, L | 1 |
| Horecker, BL; Melloni, E; Michetti, M; Pontremoli, S; Sacco, O; Salamino, F; Sparatore, B | 1 |
| Authi, KS; Kakkar, VV; Patel, Y | 1 |
| Banik, NL; Barbosa, E; Chakrabarti, AK; Deshpande, RV; Goust, JM; Hogan, EL | 1 |
| Bosca, L; Crawford, C; Junco, M; Parker, PJ; Webster, C | 1 |
| Beermann, ML; Griffin, WR; Leli, U; Shea, TB | 1 |
| Dwyer, LD; Jaken, S; Malkinson, AM; Miller, AC; Parks, AL | 1 |
| Al, Z; Cohen, CM | 1 |
| Ariyoshi, H; Kambayashi, J; Kawashima, S; Mori, T; Sakon, M; Shiba, E; Yoshida, K | 1 |
| Imajoh-Ohmi, S; Kanegasaki, S; Kikuchi, H | 1 |
| Banik, NL; Deshpande, RV; Goust, JM; Hogan, EL | 1 |
| Gautero, H; Geny, B; Lecomte, MC; Lukowski, S; Marin, P; Mira, JP; Russo-Marie, F | 1 |
| Dinsdale, D; Dwyer-Nield, LD; Malkinson, AM; Miller, AC; Neighbors, BW | 1 |
| Druker, BJ; Handa, M; Ikeda, Y; Miyakawa, Y; Oda, A; Ohashi, H; Ozaki, K | 1 |
| Echevaria-Vázquez, D; Fagard, R; Lijnen, P; Petrov, V | 1 |
| Fagard, R; Lijnen, P; Petrov, V | 1 |
| Banfić, H; Rittenhouse, SE; Straforini, F; Tosi, L; Volinia, S; Zhang, J | 1 |
| Hiwasa, T; Kondo, K; Nakagawara, A; Nakamura, Y; Ozaki, T; Saido, T; Sakiyama, S | 1 |
| Byzova, TV; Plow, EF | 1 |
| Joly, A; Kerwar, SS; Lum, RT; Meyer, SM; Nelson, MG; Schow, SR; Shiffman, D; Wick, MM | 1 |
| Demotz, S; Iwashima, M; Martinon, F; Müller, S; Penna, D; Valitutti, S | 1 |
| Berry, DM; Meckling-Gill, KA | 1 |
| de Barry, J; Janoshazi, A | 1 |
| Ekinci, FJ; Shea, TB | 1 |
| Li, HL; Liu, L; Malek, SK; Zimmerman, UJ | 1 |
| Fisher, C; Gonzalez, B; Rosser, BG | 1 |
| Brooks, WH; Dix, AR; Rock, MT; Roszman, TL | 1 |
| Bleijs, DA; Figdor, CG; Thijssen, JP; van Duijnhoven, GC; van Kooyk, Y; van Vliet, SJ | 1 |
| Fardon, NJ; Thomas, TH; Wilkinson, R | 1 |
| Berry, DM; Clark, CS; Meckling-Gill, KA | 1 |
| Aragon, B; Brustis, JJ; Cottin, P; Dargelos, E; Ducastaing, A; Dulong, S; Levieux, D; Poussard, S; Touyarot, K | 1 |
| Aki, T; Uemura, K; Yamaguchi, K; Yoshida, Ki | 1 |
| Imai, K; Kunimatsu, M; Liu, ZQ; Manabe, T; Okamoto, T; Sasaki, M; Takeyama, H; Teranishi, F | 1 |
| Brown, EM; Butters, RR; Kifor, I; Kifor, O; Moore, FD | 1 |
| Black, JD; Leontieva, OV | 1 |
| Brustis, JJ; Cottin, P; Dedieu, S; Mazères, G; Poussard, S | 1 |
| Eggo, MC; Langman, MJ; Lewis, AE; Susarla, R; Wong, BC | 1 |
| Cottin, P; Dulong, S; Goudenege, S; Poussard, S | 1 |
| Tardif, MR; Tremblay, MJ | 1 |
| Chen, HC; Lin, LY; Tsai, JS; Yang, PM | 1 |
| Barnett, CD; Mao, CD; Struewing, IT; Yadav, S; Zhang, W | 1 |
| Hayakawa, H; Hayakawa, M; Matsuyama, Y; Okazaki, H; Tamemoto, H; Tominaga, S | 1 |
| Chiba, S; Kozuma, Y; Ninomiya, H; Sawahata, Y; Takei, Y | 1 |
| Adler, KB; Crews, AL; Fang, S; Lampe, WR; Park, J | 1 |
2 review(s) available for tetradecanoylphorbol acetate and calpain
| Article | Year |
|---|---|
Limited proteolysis of protein kinase C by calpain, its possible implication.
Topics: Amino Acid Sequence; Animals; Calpain; Diglycerides; Enzyme Activation; Isoenzymes; Molecular Sequence Data; Organ Specificity; Phospholipids; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
The role of intracellular proteinases in human neutrophil activation.
Topics: Calpain; Cell Compartmentation; Cytoskeletal Proteins; Cytoskeleton; Humans; Macromolecular Substances; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Protein Kinase C; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1989 |
57 other study(ies) available for tetradecanoylphorbol acetate and calpain
| Article | Year |
|---|---|
Induction of protein kinase C down-regulation by the phorbol ester TPA in a calpain/protein kinase C complex.
Topics: Animals; Calcium; Calpain; Dose-Response Relationship, Drug; Down-Regulation; In Vitro Techniques; Male; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1992 |
Specific increase in calcium-activated neutral protease with low calcium sensitivity (m-calpain) in proerythroblastic K562 cell line cells induced to differentiation by phorbol 12-myristate 13-acetate.
Topics: Blotting, Western; Calpain; Cell Differentiation; Cell Nucleus; Enzyme Activation; Erythroblasts; Humans; Immunoenzyme Techniques; In Vitro Techniques; Leukemia, Myeloid, Chronic-Phase; Microscopy, Electron; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1992 |
Transcriptional activation of the gene for the large subunit of human m-calpain by 12-o-tetradecanoyl-phorbol-13-acetate.
Topics: Calcium-Binding Proteins; Calpain; Gene Expression Regulation; HeLa Cells; Humans; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1992 |
Purification and characterization of protein kinase C epsilon from rabbit brain.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Brain; Calcium; Calpain; Cattle; Enzyme Activation; Hydrolysis; Immune Sera; Molecular Sequence Data; Phospholipids; Phosphorylation; Protein Kinase C; Rabbits; Substrate Specificity; Tetradecanoylphorbol Acetate | 1992 |
Inhibition of the calpain-mediated proteolysis of protein kinase C enhances lytic activity in human NK cells.
Topics: Adult; Antibody-Dependent Cell Cytotoxicity; Biological Transport; Calpain; Glycoproteins; Humans; Interleukin-2; Killer Cells, Natural; Lymphocyte Activation; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Effects of the calpain inhibitor E64-d on platelet activation responses.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Arachidonic Acids; Calpain; Collagen; Humans; In Vitro Techniques; Leucine; Phosphatidic Acids; Platelet Activation; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Possible involvement of calpain in down-regulation of protein kinase C.
Topics: Amino Acid Sequence; Calpain; Enzyme Activation; Humans; Molecular Sequence Data; Neoplasm Proteins; Neuroblastoma; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Isozymes of protein kinase C in human neutrophils and their modification by two endogenous proteinases.
Topics: Animals; Brain; Calpain; Chromatography, Gel; Cross Reactions; Cytosol; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Humans; Isoenzymes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Rats; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1990 |
The thiol proteinase inhibitors improve the abnormal rapid down-regulation of protein kinase C and the impaired natural killer cell activity in (Chediak-Higashi syndrome) beige mouse.
Topics: Animals; Calpain; Chediak-Higashi Syndrome; Cysteine Proteinase Inhibitors; Cytotoxicity, Immunologic; Disease Models, Animal; Killer Cells, Natural; Killer Factors, Yeast; Leucine; Leupeptins; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Protein Biosynthesis; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate | 1989 |
Activation of neutrophil calpain following its translocation to the plasma membrane induced by phorbol ester or fMet-Leu-Phe.
Topics: Antibodies, Monoclonal; Calpain; Cell Membrane; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1989 |
Thrombin stimulates the activities of multiple previously unidentified protein kinases in platelets.
Topics: Amino Acids; Blood Platelets; Blood Proteins; Calpain; Enzyme Activation; Histones; Humans; Immunoblotting; In Vitro Techniques; Ionomycin; Molecular Weight; Platelet Activation; Protein Kinases; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Effects of a monoclonal anti-calpain antibody on responses of stimulated human neutrophils. Evidence for a role for proteolytically modified protein kinase C.
Topics: Animals; Antibodies, Monoclonal; Calpain; Mice; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Hydrolases; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
The involvement of calpain in the activation of protein kinase C in neutrophils stimulated by phorbol myristic acid.
Topics: Calpain; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Activation; Humans; Neutrophils; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Redistribution of protein kinase C during mitogenesis of human B lymphocytes.
Topics: B-Lymphocytes; Calpain; Cell Cycle; Cytoplasm; Ethers; Humans; Ionomycin; Lymphocyte Activation; Membranes; Palatine Tonsil; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Biochemical responses in activated human neutrophils mediated by protein kinase C and a Ca2+-requiring proteinase.
Topics: Calpain; Cytochalasin B; Endopeptidases; Exocytosis; Humans; Hydrogen Peroxide; Leupeptins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Retinaldehyde; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Trifluoperazine | 1986 |
Calpain-induced down-regulation of protein kinase C inhibits dense-granule secretion in human platelets. Inhibition of platelet aggregation or calpain activity preserves protein kinase C and restores full secretion.
Topics: Blood Platelets; Calpain; Down-Regulation; Humans; Ionomycin; Male; Oligopeptides; Phosphorylation; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Serotonin; Tetradecanoylphorbol Acetate | 1994 |
Calpain expression in lymphoid cells. Increased mRNA and protein levels after cell activation.
Topics: Blood; Calcimycin; Calpain; Cell Line; Cycloheximide; Dexamethasone; Dichlororibofuranosylbenzimidazole; Gene Expression Regulation; Humans; Interferon-gamma; Lymphocyte Activation; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Protein kinase C V3 domain mutants with differential sensitivities to m-calpain are not resistant to phorbol-ester-induced down-regulation.
Topics: Amino Acid Sequence; Animals; Calpain; Cattle; Cells, Cultured; Down-Regulation; Hydrolysis; Molecular Sequence Data; Mutagenesis; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
Degradation of protein kinase C alpha and its free catalytic subunit, protein kinase M, in intact human neuroblastoma cells and under cell-free conditions. Evidence that PKM is degraded by mM calpain-mediated proteolysis at a faster rate than PKC.
Topics: Calpain; Cell-Free System; Humans; In Vitro Techniques; Isoenzymes; Neuroblastoma; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1994 |
Calpain-induced downregulation of activated protein kinase C-alpha affects lung epithelial cell morphology.
Topics: Animals; Calpain; Cell Line; Cell Line, Transformed; Cytosol; Epithelial Cells; Epithelium; Indoles; Isoenzymes; Kinetics; Lung; Maleimides; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Phorbol 12-myristate 13-acetate-stimulated phosphorylation of erythrocyte membrane skeletal proteins is blocked by calpain inhibitors: possible role of protein kinase M.
Topics: Amino Acid Sequence; Blood Proteins; Calpain; Down-Regulation; Erythrocyte Membrane; Glycoproteins; Humans; In Vitro Techniques; Leupeptins; Membrane Proteins; Molecular Sequence Data; Phosphorylation; Protease Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
Translocation of human platelet calpain-I.
Topics: Blood Platelets; Calcium-Binding Proteins; Calpain; Cell Membrane; Collagen; Cysteine Proteinase Inhibitors; Edetic Acid; Humans; Immunoblotting; Intracellular Membranes; Ionomycin; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Novel antibodies specific for proteolyzed forms of protein kinase C: production of anti-peptide antibodies available for in situ analysis of intracellular limited proteolysis.
Topics: Amino Acid Sequence; Animals; Antibodies; Antibody Formation; Calcimycin; Calpain; Cell Line; Immunoblotting; Immunohistochemistry; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1993 |
Calpain secreted by activated human lymphoid cells degrades myelin.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Calcium; Calcium-Binding Proteins; Calpain; Chelating Agents; Culture Media, Conditioned; Demyelinating Diseases; Egtazic Acid; Humans; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, Large B-Cell, Diffuse; Monocytes; Myelin Basic Protein; Myelin Sheath; Neoplasm Proteins; Protease Inhibitors; Rabbits; Rats; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Inhibition of phospholipase D activity by fodrin. An active role for the cytoskeleton.
Topics: Adenylyl Cyclases; Animals; Calcium; Calmodulin; Calpain; Carrier Proteins; Cattle; Cytoskeleton; Enzyme Activation; Guanosine Triphosphate; HL-60 Cells; Humans; Microfilament Proteins; Phosphatidylcholines; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phospholipases A; Signal Transduction; Spectrin; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1996 |
Cytoskeletal architecture in mouse lung epithelial cells is regulated by protein-kinase C-alpha and calpain II.
Topics: Animals; Blotting, Western; Calpain; Cytoskeletal Proteins; Cytoskeleton; Epithelial Cells; Epithelium; Immunohistochemistry; Isoenzymes; Lung; Mice; Microscopy, Electron, Scanning; Protein Kinase C; Protein Kinase C-alpha; Talin; Tetradecanoylphorbol Acetate | 1996 |
Thrombopoietin and thrombin induce tyrosine phosphorylation of Vav in human blood platelets.
Topics: Animals; Blood Platelets; Calpain; Cell Cycle Proteins; Cytoskeleton; Humans; Ionomycin; Phosphorylation; Platelet Aggregation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Rats; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thrombopoietin | 1997 |
Protein kinase C induced changes in erythrocyte Na+/H+ exchange and cytosolic free calcium in humans.
Topics: Calcium; Calpain; Carcinogens; Cytosol; Enzyme Inhibitors; Erythrocytes; Humans; Protein Kinase C; Sodium; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate | 1998 |
Activation by calcium of erythrocyte Na+/H+ exchange in men.
Topics: Calcium; Calpain; Cysteine Proteinase Inhibitors; Down-Regulation; Erythrocytes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Ion Transport; Kinetics; Leucine; Male; Protein Kinase C; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1998 |
A type II phosphoinositide 3-kinase is stimulated via activated integrin in platelets. A source of phosphatidylinositol 3-phosphate.
Topics: Androstadienes; Blood Platelets; Calcium; Calpain; Enzyme Activation; Humans; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protease Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin | 1998 |
Down-regulation of protein kinase C alpha and gamma and enhanced TPA-induced neurite formation in DAN-transfected neuroblastoma cells.
Topics: 3T3 Cells; Animals; Blotting, Western; Calpain; Carrier Proteins; Cell Cycle Proteins; Cytokines; Dexamethasone; Down-Regulation; Fibroblasts; Humans; Isoenzymes; Mice; Microfilament Proteins; Molecular Weight; Nerve Tissue Proteins; Neurites; Neuroblastoma; Neurons; Protein Kinase C; Protein Kinase C-alpha; Proteins; Rats; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Activation of alphaVbeta3 on vascular cells controls recognition of prothrombin.
Topics: Adenosine Diphosphate; Aorta; Calpain; Cytochalasin B; Endothelium, Vascular; Fibrinogen; Hemostasis; Homeostasis; Humans; Manganese; Oligopeptides; Protein Kinase C; Prothrombin; Receptors, Vitronectin; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
A new structural class of proteasome inhibitors that prevent NF-kappa B activation.
Topics: Adenosine Triphosphatases; Animals; Brain; Calpain; Cattle; Cell Division; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dipeptides; Female; Lipopolysaccharides; Macrophages; Mice; Multienzyme Complexes; NF-kappa B; Phosphorylation; Proteasome Endopeptidase Complex; Signal Transduction; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Degradation of ZAP-70 following antigenic stimulation in human T lymphocytes: role of calpain proteolytic pathway.
Topics: Antigen-Presenting Cells; Antigens; Calpain; Cell Line, Transformed; Clone Cells; Down-Regulation; Humans; Hydrolysis; Lymphocyte Activation; Membrane Proteins; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; ZAP-70 Protein-Tyrosine Kinase | 1999 |
Vitamin D analogs, 20-Epi-22-oxa-24a,26a,27a,-trihomo-1alpha,25(OH)2-vitamin D3, 1,24(OH)2-22-ene-24-cyclopropyl-vitamin D3 and 1alpha,25(OH)2-lumisterol3 prime NB4 leukemia cells for monocytic differentiation via nongenomic signaling pathways, involving
Topics: Biological Transport; Calcitriol; Calcium; Calpain; Cell Differentiation; Cell Nucleus; Cellular Senescence; Humans; Intracellular Membranes; Isoenzymes; Leukemia; Monocytes; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Receptors, Calcitriol; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vitamin D | 1999 |
Rapid in vitro conformational changes of the catalytic site of PKC alpha assessed by FIM-1 fluorescence.
Topics: Animals; Binding Sites; Calcium; Calpain; Catalytic Domain; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Precursors; Fluoresceins; Fluorescent Dyes; Humans; Hydrolysis; Indoles; Isoenzymes; Kinetics; Phosphatidylserines; Protein Conformation; Protein Kinase C; Protein Kinase C-alpha; Rabbits; Rats; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1999 |
Free PKC catalytic subunits (PKM) phosphorylate tau via a pathway distinct from that utilized by intact PKC.
Topics: Autoradiography; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Calpain; Catalysis; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Densitometry; Enzyme Activators; Enzyme Inhibitors; Humans; Immunoblotting; Immunohistochemistry; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Protein Kinase C; tau Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Proteolysis of synaptobrevin, syntaxin, and SNAP-25 in alveolar epithelial type II cells.
Topics: Animals; Antigens, Surface; Blotting, Western; Calcimycin; Calpain; Epithelial Cells; Fluorescent Antibody Technique; Glycoproteins; Ionophores; Membrane Proteins; Nerve Tissue Proteins; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; R-SNARE Proteins; Rats; Secretory Rate; Synaptosomal-Associated Protein 25; Syntaxin 1; Tetradecanoylphorbol Acetate | 1999 |
Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity.
Topics: Animals; Apoptosis; Biological Transport; Calpain; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Glycochenodeoxycholic Acid; Liver; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2000 |
Beta1 integrin-mediated T cell adhesion and cell spreading are regulated by calpain.
Topics: Adult; Antibodies, Monoclonal; Calpain; CD3 Complex; Cell Adhesion; Cell Movement; Cells, Cultured; Cysteine Proteinase Inhibitors; Dipeptides; Fibronectins; Humans; Integrin beta1; Lymphocyte Activation; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2000 |
A single amino acid in the cytoplasmic domain of the beta 2 integrin lymphocyte function-associated antigen-1 regulates avidity-dependent inside-out signaling.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Antibodies, Monoclonal; Calpain; Cell Adhesion; Cell Line, Transformed; Cells, Cultured; Cytoplasm; Cytoskeleton; Enzyme Activation; Flow Cytometry; Humans; Intercellular Adhesion Molecule-1; K562 Cells; Lymphocyte Function-Associated Antigen-1; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Molecular Sequence Data; Mutagens; Mutation; Phosphorylation; Point Mutation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transfection | 2001 |
Rapid fusion of granules with neutrophil cell membranes in hypertensive patients may increase vascular damage.
Topics: Adult; Albuminuria; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Blood Vessels; Calpain; Carcinogens; Cell Fusion; Cell Membrane; Cysteine Proteinase Inhibitors; Cytoplasmic Granules; Enzyme Inhibitors; Female; Humans; Hypertension; Indoles; Lectins, C-Type; Leucine; Lipids; Macrophage-1 Antigen; Male; Maleimides; Metabolic Syndrome; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Tetradecanoylphorbol Acetate | 2001 |
1alpha,25-dihydroxyvitamin D3 stimulates phosphorylation of IkappaBalpha and synergizes with TPA to induce nuclear translocation of NFkappaB during monocytic differentiation of NB4 leukemia cells.
Topics: Active Transport, Cell Nucleus; Calcitriol; Calcium Signaling; Calpain; Cell Differentiation; Cell Nucleus; DNA-Binding Proteins; Drug Synergism; Humans; I-kappa B Kinase; I-kappa B Proteins; Leukemia, Promyelocytic, Acute; Monocytes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Calcitriol; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor RelA; Tumor Cells, Cultured | 2002 |
Protein kinase Calpha is a calpain target in cultured embryonic muscle cells.
Topics: Animals; Calpain; Cell Differentiation; Cells, Cultured; Cytoskeletal Proteins; Gene Expression Regulation, Enzymologic; Isoenzymes; Membrane Proteins; Muscle Development; Muscle, Skeletal; Protein Kinase C; Protein Kinase C-alpha; Rats; Rats, Wistar; Substrate Specificity; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Protein kinase C-epsilon protects PC12 cells against methamphetamine-induced death: possible involvement of suppression of glutamate receptor.
Topics: Adrenergic Agents; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Blotting, Western; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calpain; Caspase Inhibitors; Cell Survival; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; In Situ Nick-End Labeling; Isoenzymes; Methamphetamine; Naphthalenes; Oligonucleotides, Antisense; PC12 Cells; Protein Kinase C; Protein Kinase C-epsilon; Rats; Receptors, Glutamate; Tetradecanoylphorbol Acetate; Transfection | 2003 |
Calpain is involved in the HIV replication from the latently infected OM10.1 cells.
Topics: Acetylcysteine; Binding Sites; Calcimycin; Calcium Signaling; Calcium-Binding Proteins; Calpain; Cell Line; Glycoproteins; HIV-1; Humans; I-kappa B Proteins; In Vitro Techniques; Ionophores; Leucine; NF-kappa B; NF-KappaB Inhibitor alpha; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Virus Replication | 2003 |
m-Calpain colocalizes with the calcium-sensing receptor (CaR) in caveolae in parathyroid cells and participates in degradation of the CaR.
Topics: Animals; Autolysis; Calcium; Calpain; Carcinogens; Cattle; Caveolae; Caveolin 1; Caveolins; Cell Line; Humans; Isoenzymes; Parathyroid Glands; Parathyroid Hormone; Phosphorylation; Protein Kinase C; Rabbits; Receptors, Calcium-Sensing; Receptors, Cell Surface; Substrate Specificity; Tetradecanoylphorbol Acetate | 2003 |
Identification of two distinct pathways of protein kinase Calpha down-regulation in intestinal epithelial cells.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Bryostatins; Calpain; Cell Line, Tumor; Cell Membrane; Cells, Cultured; Cysteine Endopeptidases; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Intestinal Mucosa; Lactones; Macrolides; Marine Toxins; Microscopy, Fluorescence; Models, Biological; Multienzyme Complexes; Okadaic Acid; Oxazoles; Phosphorylation; Precipitin Tests; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Kinase C-alpha; Rats; Signal Transduction; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors; Ubiquitin | 2004 |
Myoblast migration is prevented by a calpain-dependent accumulation of MARCKS.
Topics: Animals; Antibodies; Binding Sites; Calpain; Cell Line; Cell Movement; Immunoblotting; Intracellular Signaling Peptides and Proteins; Lipoproteins; Membrane Proteins; Mutation; Myoblasts, Skeletal; Myristoylated Alanine-Rich C Kinase Substrate; Oligodeoxyribonucleotides, Antisense; Phosphorylation; Tetradecanoylphorbol Acetate | 2003 |
Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205.
Topics: Acetamides; Acetophenones; Alkaloids; Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Benzopyrans; Calpain; Caspase 3; Caspase Inhibitors; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cysteine Proteinase Inhibitors; Dipeptides; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Histones; Humans; Indomethacin; Kinetics; Phenanthridines; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyrans; Spiro Compounds; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2005 |
Biologically active milli-calpain associated with caveolae is involved in a spatially compartmentalised signalling involving protein kinase C alpha and myristoylated alanine-rich C-kinase substrate (MARCKS).
Topics: Animals; Calpain; Carcinogens; Caveolae; Cell Compartmentation; Cell Fusion; Cytosol; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Myoblasts; Myristoylated Alanine-Rich C Kinase Substrate; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate | 2005 |
Regulation of LFA-1 activity through cytoskeleton remodeling and signaling components modulates the efficiency of HIV type-1 entry in activated CD4+ T lymphocytes.
Topics: Adjuvants, Immunologic; Calpain; CD4-Positive T-Lymphocytes; Cell Adhesion; Cell Line; Cytoskeleton; HIV-1; Humans; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; Membrane Fusion; Muromonab-CD3; Phospholipase C gamma; Phytohemagglutinins; Protein-Tyrosine Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; ZAP-70 Protein-Tyrosine Kinase | 2005 |
Cadmium induces Ca2+-dependent necrotic cell death through calpain-triggered mitochondrial depolarization and reactive oxygen species-mediated inhibition of nuclear factor-kappaB activity.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Blotting, Western; Cadmium; Calcium; Calpain; Caspase 3; Cell Death; CHO Cells; Cricetinae; Cricetulus; DNA; DNA Fragmentation; Genes, Reporter; Membrane Potentials; Mitochondrial Membranes; Necrosis; NF-kappa B; Plasmids; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 2007 |
Frizzled-7 turnover at the plasma membrane is regulated by cell density and the Ca(2+) -dependent protease calpain-1.
Topics: Amino Acid Sequence; Animals; Calcium; Calpain; Cattle; Cell Count; Cell Line; Cell Membrane; Cell Movement; Culture Media, Conditioned; Cytoplasmic Vesicles; Endocytosis; Endothelial Cells; Frizzled Receptors; Humans; Molecular Sequence Data; Mutation; Peptide Fragments; Protein Structure, Tertiary; Protein Transport; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate; Wnt Proteins | 2007 |
Mature interleukin-33 is produced by calpain-mediated cleavage in vivo.
Topics: Calcium; Calpain; Cell Line, Tumor; Endothelial Cells; Epithelial Cells; Humans; Interleukin-33; Interleukins; RNA, Small Interfering; Tetradecanoylphorbol Acetate | 2009 |
Procoagulant properties of microparticles released from red blood cells in paroxysmal nocturnal haemoglobinuria.
Topics: Blood Coagulation; Calcium; Calpain; Caspases; Cell-Derived Microparticles; Cells, Cultured; Complement Activation; Enzyme Inhibitors; Erythrocytes; Hemoglobinuria, Paroxysmal; Humans; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate | 2011 |
Calpain and MARCKS protein regulation of airway mucin secretion.
Topics: Bronchi; Calpain; Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; Fluorescence; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mucins; Myristoylated Alanine-Rich C Kinase Substrate; Oligopeptides; Protein Kinase C; Tetradecanoylphorbol Acetate | 2012 |