tetradecanoylphorbol acetate has been researched along with calcimycin in 1919 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 717 (37.36) | 18.7374 |
| 1990's | 953 (49.66) | 18.2507 |
| 2000's | 168 (8.75) | 29.6817 |
| 2010's | 76 (3.96) | 24.3611 |
| 2020's | 5 (0.26) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Epstein, ML; Estensen, RD; Hill, HR; Reusch, ME | 1 |
| Griffel, B; Honig, S; Pick, E; Seger, M | 1 |
| Gallin, JI; Schiffmann, E; Wright, DG | 1 |
| Alkhalaf, B; Ballejo, G; Gong, Y; Molnar, P; Murphy, LC; Murphy, LJ | 1 |
| Abinun, M; Ramić, Z; Stosić-Grujicić, S; Vucković, S; Vukmanović, S | 1 |
| Boscá, L; Genaro, AM; Hortelano, S | 1 |
| Inoue, Y; Kasahara, K; Kondo, N; Mori, S; Motoyoshi, F; Orii, T | 1 |
| Bardos, P; Degenne, D; Girard, AC; Guillaumin, JM; Lacord, M; Thibault, G | 1 |
| al-Ubaidi, F; Cornford, PA; Holt, JR; Monaghan, H; Schrey, MP | 1 |
| Emoto, S; Ichikawa, A; Miyazaki, T; Ohgoh, M; Ohmori, E; Yamamoto, J; Yatsunami, K | 1 |
| Funk, CD; Greenberg, SM; Romano, M; Serhan, CN; Sheppard, KA | 1 |
| Britigan, BE; Roeder, TL; Shasby, DM | 1 |
| McCaffrey, PG; Minowada, J; Oghiso, Y; Shibata, Y; Volkman, A | 1 |
| Fukuda, M; Maeda, K; Tagami, H; Tomita, Y | 1 |
| Berthelon, MC; Hall, SH; Jaillard, C; Saez, JM; Viard, I | 1 |
| Bot, AG; de Jonge, HR; Vaandrager, AB; van den Berghe, N | 1 |
| Davis, BB; Jacob, AK; Reznikoff, CA; Thomas, DJ; Zenser, TV | 1 |
| Carter, DM; Gottlieb, AB; Krane, JF; Krueger, JG | 1 |
| Burd, PR; Coligan, JE; Ehrenreich, H; Fauci, AS; Garfield, M; Hültner, L; Hylton, JB; Metcalfe, DD; Rottem, M | 1 |
| David, M; Griesmacher, A; Horvath, G; Mueller, MM; Weigel, G | 1 |
| Decker, K; Dieter, P; Duyster, J; Hidaka, H | 1 |
| Ireland, ME; Welsh, MJ | 1 |
| Chihara, K; Fukase, M; Kano, J; Sugimoto, T | 2 |
| Conn, PM; Hawes, BE; Marzen, JE; Waters, SB | 1 |
| Kellner, RG; Van der Kraak, G | 1 |
| Hinko, A; Soloff, MS | 1 |
| Bird, IM; Clyne, CD; Dochrell, M; Lightly, ER; Walker, SW; Williams, BC | 1 |
| Franson, RC; Lattanzio, KS; Rosenthal, MD | 1 |
| Ebbeling, L; Gerrard, JM; McNicol, A; Robertson, C | 1 |
| Favus, MJ; Ro, HK; Tembe, V | 1 |
| Blackman, MR; Maki, T; Miyamoto, A; Roth, GS | 1 |
| Hruska, KA; Moskowitz, DW | 1 |
| Freemont, AJ; Hayes, ME; Mawer, EB; Yuan, JY | 1 |
| Hanson, PJ; Keates, AC; Williams, JM | 1 |
| Dieter, P; Duyster, J; Fitzke, E; Schulze-Specking, A | 1 |
| Déniz, A; Estevez, F; Fanjul, LF; Gonzalez, J; Quintana, J; Ruiz de Galarreta, CM; Santana, P | 1 |
| Avioli, LV; Cheng, SL; Fausto, A; Jänne, OA | 1 |
| Cramer, R; Knowles, A; Menegazzi, R; Patriarca, P; Zabucchi, G | 1 |
| Hum, DW; Miller, WL; Moore, CC | 1 |
| Aitken, RJ; Buckingham, DW; West, KM | 1 |
| Edwards, PA; Wilkin, DJ | 1 |
| Desai, SN; Letts, GL; Myers, CL; Schembri-King, J; Wallace, RW | 1 |
| Chizzonite, R; Danho, W; Gately, MK; Hulmes, JD; Levin, W; Nanduri, VB; Pan, YC; Podlaski, FJ; Stern, AS | 1 |
| Frohman, LA; Soszynski, PA | 1 |
| Baba, T; Fujisawa, H; Horiuchi, S; Naito, Y; Otsuka, F | 1 |
| Funakoshi, A; Kitayama, N; Matsuoka, Y; Tateishi, K | 1 |
| Higgins, DA | 1 |
| Akdeniz, H; Bastiani, L; el-Khatib, M; Ju, ST; Kuchroo, V; Ozdemirli, M | 1 |
| Bowyer, JF; Dreyer, E; Houchi, H; Masserano, JS; Nakanishi, A; Sterling, C; Tank, AW; Weiner, N | 1 |
| el-Ghazaly, M; Moore, AR; Willoughby, DA | 1 |
| Benacerraf, B; Freeman, GJ; Gimmi, CD; Nadler, LM; Razi-Wolf, Z; Reiser, H | 1 |
| Berlin, C; Bührer, C; Hamann, A; Holzmann, B; Jablonski-Westrich, D; Thiele, HG | 1 |
| Karnovsky, MJ; Ottlinger, ME; Pukac, LA | 1 |
| Andrews, PE; Montgomery, BT; Tindall, DJ; Young, CY | 1 |
| Bergstrand, H; Karabelas, K; Lundquist, B; Michelsen, P | 1 |
| Barrett, KE; Gigli, I; Yen, A | 1 |
| Farber, JM | 1 |
| Ackerman, SJ; Dvorak, AM; Golightly, LM; Thomas, LL | 1 |
| Heller, DN; Raffin, TA; Schumann, MA; Tanigaki, T | 1 |
| Besmer, P; Buck, J; Huang, EJ; Nocka, KH | 1 |
| Cairo, MS; Clark, S; Dana, R; Knoppel, E; Park, L; Sender, L; Suen, Y; van de Ven, C | 1 |
| Bargon, J; Crystal, RG; Dalemans, W; Lecocq, JP; Pavirani, A; Trapnell, BC; Yoshimura, K | 1 |
| Durum, SK; Kung, HF; Ramsburg, EA; Smith, MR | 1 |
| López-Botet, M; Rincón, M; Tugores, A | 1 |
| Grosman, N | 5 |
| Lalani, S; Mills, GB; Peters, WJ; Sparkes, BG; Teodorczyk-Injeyan, JA | 1 |
| Gardner, JD; Jensen, RT; Metz, DC; Mrozinski, JE; Patto, RJ; Turner, RJ | 1 |
| Mio, M; Tasaka, K; Yoshida, T | 1 |
| Chang, JP; Jobin, RM | 1 |
| Boarder, MR; Wilkes, LC | 1 |
| Church, DJ; Erbrich, AC; Lang, U; Vallotton, MB | 1 |
| Chabot, MC; Kennerly, DA; McCall, CE; McPhail, LC; Wykle, RL | 1 |
| Graham, GG; Joulianos, G; Rudkowski, R; Ziegler, JB | 1 |
| Gutman, Y; Zilberman, Y | 1 |
| Dailey, LA; Devlin, RB; Friedman, M; McKinnon, K; Noah, TL; Samet, JM; Yankaskas, JR | 1 |
| Rabkin, SW; Sunga, PS | 1 |
| Kinugasa, T; Kuroki, M; Matsuo, Y; Matsuoka, Y | 1 |
| Hansen, PJ; Li, J; Roberts, RM; Skopets, B; Thatcher, WW | 1 |
| Borger, P; Dokter, WH; Halie, MR; Hendriks, D; van der Horst, I; Vellenga, E | 1 |
| Smith, DM; Waite, M | 1 |
| Alkhalaf, B; Gong, Y; Murphy, LC; Murphy, LJ | 1 |
| Doron, DA; Feuerstein, G; Hallenbeck, JM; Heldman, E; McCarron, RM; Pollard, HB; Sirén, AL; Spatz, M | 1 |
| Krämer, K; Markwitan, A; Montigel, C; Pallauf, J | 1 |
| Batt, DG; Collins, RJ; Corbett, RL; Green, AM; Harris, RR; Wadman, EA; Wright, SW | 1 |
| Crocicchio, F; D'Adamio, F; Migliorati, G; Nicoletti, I; Pagliacci, C; Riccardi, C | 1 |
| Kyd, JM; Murdoch, RN | 1 |
| Jullian, EH; Le Garrec, YC; Michel, PJ; Pompidou, AJ; Teyssier, MM | 1 |
| Rivera-Rodríguez, N; Rodríguez-del Valle, N | 1 |
| Tatarintsev, AV; Varfolomeyev, SD; Vrzheshch, PV; Yershov, DE | 1 |
| Kimura, F; Shinmei, M; Watanabe, K | 1 |
| González-Molina, A; Hernández-Godoy, J; Planelles, D | 1 |
| Carew, MA; Paleolog, EM; Pearson, JD | 1 |
| Issekutz, TB; Wysocki, J | 1 |
| Abe, E; Arai, K; Arai, N; De Waal Malefyt, R; Matsuda, I | 1 |
| Herrick, T; Qian, L; Wilkinson, MF | 1 |
| Hammond, GL; Nelson, PJ; Peyman, JA | 1 |
| Gannon, DE; Karmiol, S; Phan, SH; Ward, PA | 1 |
| Dominguez, J; Garcia, JG; Natarajan, V; Patterson, CE; Stasek, J | 1 |
| Ganguly, NK; Gorowara, S; Mahajan, RC; Walia, BN | 1 |
| Berglindh, T; Nygård, G | 2 |
| Burrow, GN; Eggo, MC; Lippes, H | 1 |
| Deyrup-Olsen, I; Louie, H; Luchtel, DL; Martin, AW | 1 |
| Chao, W; Hanahan, DJ; Liu, H; Olson, MS | 2 |
| Koren, R; Liberman, UA; Novogrodsky, A; Ravid, A; Zilberman, Y | 1 |
| Boarder, MR; Jones, JA; Owen, PJ; Purkiss, J | 1 |
| Das, B; Fricker, LD; Klein, RS | 1 |
| Chizzonite, R; Desai, BB; Gately, MK; Mongini, PK; Quinn, PM; Wolitzky, AG | 1 |
| Ning, JT; Wornom, IL | 1 |
| Garcia-Sanz, JA; Lichtenheld, MG; Lu, P; Podack, ER | 1 |
| Raufman, JP | 1 |
| Crocicchio, F; Migliorati, G; Moraca, R; Nicoletti, I; Pagliacci, C; Riccardi, C | 1 |
| McKinney, EC | 1 |
| Chakraborti, S; Michael, JR; Sanyal, T | 1 |
| Maruo, T; Matsuo, H; Mochizuki, M; Nishino, R | 2 |
| Azula, FJ; Font, J; Macarulla, JM; Marino, A; Nieva, N; Trueba, M | 1 |
| Bocckino, SB; Murray, JJ; Truett, AP | 1 |
| Brandwein, SR; Maenz, L | 1 |
| Belfiore, CJ; Knickerbocker, JJ; Niswender, GD; Wiepz, GJ; Wiltbank, MC | 1 |
| Lameh, J; Moro, O; Philip, M; Ramachandran, J; Sadée, W; Sharma, YK | 1 |
| Knopf, JL; Lin, AY; Lin, LL | 1 |
| Blok, LJ; de Jong, FH; Grootegoed, JA; Klaij, IA; Timmerman, MA | 1 |
| Kantorski, J; Tchórzewski, H | 1 |
| Bierman, EL; Mendez, AJ; Oram, JF | 1 |
| Kosano, H; Kugai, N; Nagata, N; Wada, S; Yasutomo, Y | 1 |
| Fusamoto, H; Hayashi, N; Kamada, T; Kasahara, A; Katayama, K; Sasaki, Y; Takehara, T; Towata, T | 1 |
| 'T Hart, BA; de Mol, NJ; Janssen, LH; Kelder, PP | 1 |
| Fujie, K; Handa, H; Mino, M; Nishihira, J; Sakamoto, W | 1 |
| Basbaum, CB; Cherqui, G; Hermelin, B; Mergey, M; Paul, A; Picard, J; Veissière, D | 1 |
| Calle, R; Ganesan, S; Rasmussen, H; Zawalich, KC; Zawalich, WS | 1 |
| Dickler, HB; Laszlo, G | 1 |
| Oyanagui, Y; Sato, S | 1 |
| Brostrom, CO; Brostrom, MA; Galuska-Malara, EM; Prostko, CR | 1 |
| Brahmi, Z; Hommel-Berrey, GA; Shenoy, AM | 1 |
| Feldman, D; Krishnan, AV | 1 |
| Amiel, C; Friedlander, G; Le Goas, F | 1 |
| Chik, CL; Ho, AK | 1 |
| Osaki, T; Ueta, E; Yamamoto, T; Yoneda, K | 1 |
| Kasuga, M; Konda, Y; Matozaki, T; Matsuda, K; Nagao, M; Nakano, O; Nishisaki, H; Sakamoto, C; Suzuki, T; Wada, K | 1 |
| Falcone, DJ; McCaffrey, TA; Vergilio, JA | 1 |
| Barreto, A; Butler, B; Chan, WW; Cheng, K; Smith, RG | 1 |
| Lankford, KL; Letourneau, PC | 1 |
| Abramson, SB; Kitsis, EA; Weissmann, G | 1 |
| Balazovich, K; McNish, RW; Peters-Golden, M; Sporn, PH | 1 |
| Fujie, K; Handa, H; Sakamoto, W | 1 |
| Baird, S; Bulloch, K; Darko, D; Radojcic, T; Smith, D | 1 |
| Colucci, M; Conese, M; Fumarulo, R; Giordano, D; Montemurro, P; Riccardi, S; Semeraro, N | 1 |
| Harris, T; Stewart, AG | 1 |
| Bustelo, XR; Freire, M; Gómez-Márquez, J; Otero, A | 1 |
| Hader, N; Kinarty, A; Lahat, N; Rimon, D | 1 |
| Bertotto, A; Gerli, R; Grignani, F; Rondoni, F; Scalise, F; Spinozzi, F | 1 |
| Masuda, Y; Takanaka, K; Taniguchi, K | 2 |
| Cugini, CD; Leidy, JW; Millard, WJ | 1 |
| Aragón, C; Casado, M; Giménez, C; Zafra, F | 1 |
| Fitzharris, P; Knight, RA; Lightman, SL; Stephanou, A | 1 |
| Blanchard, LM; Larose, L; Morisset, J; Paquette, B | 1 |
| Deschepper, CF; Gardner, DG; LaPointe, MC; Wu, JP | 1 |
| Chakravarty, N; Hansen, M; Kjeldsen, B; Nielsen, EH | 1 |
| Crystal, RG; Nagaoka, I; Trapnell, BC | 1 |
| Gardner, JD; Jensen, RT; Murakami, M; Sharp, CM; Vinayek, R | 1 |
| Collado, A; Garrido, F; Gomez, O; Pedrinaci, S; Ruiz-Cabello, F | 1 |
| Drexler, HG; Gignac, SM; Hoffbrand, AV; Pettit, GR | 1 |
| Bach, FH; Duquesnoy, RJ; Eiras, G; Fung, JJ; Starzl, T; Todo, S; Zeevi, A | 1 |
| Johnson, AL; Tilly, JL | 3 |
| Boyer, M; Green, DR; Paskar, L; Sahai, BM; Shi, YF; Singh, B; Szalay, MG | 1 |
| Ciccarelli, A; Cirillo, R; Condorelli, M; Marone, G; Pettit, GR; Siri, L; Triggiani, M | 1 |
| Berkow, RL; Dodson, RW | 1 |
| Buschle, M; Drexler, HG; Gignac, SM; Hoffbrand, AV | 1 |
| Chakravarty, N | 1 |
| Benhamou, M; Gutkind, JS; Robbins, KC; Siraganian, RP | 1 |
| Asano, T; Matsumoto, K; Matuzaki, G; Nomoto, K; Yoshikai, Y | 1 |
| Bonak, V; Casnellie, JE; Huang, CK; Laramee, GR | 1 |
| Brent, LH; Bubien, JK; Butler, JL; Woods, WT | 1 |
| Brentano, ST; Miller, WL; Moore, CC | 1 |
| Kawasaki, C; Matsuguchi, T; Niho, Y; Okamura, S | 1 |
| Bartlett, WC; McCann, J; Noelle, RJ; Roy, M; Shepherd, DM | 1 |
| Adachi, S; Jozaki, K; Kitamura, Y; Kuriu, A; Tarui, S; Waki, N; Yamatodani, A | 1 |
| Clancy, JP; McCann, JD; Welsh, MJ | 1 |
| Dorkin, HL; Grubman, SA; Iannuzzi, MC; Jefferson, DM; Klinger, KW; Li, M; Marini, FC; Valentich, JD; Welsh, MJ | 1 |
| Adolphson, RL; Chestnut, JC; Conroy, MC; Kennedy, JA; Thueson, DO; Wright, CD | 1 |
| Duquesnoy, RJ; Eiras, G; Shimizu, Y; van Seventer, GA; Zeevi, A | 1 |
| Ervens, J; Seifert, R | 1 |
| Nanu, L; Ozanne, B; Smith, RG; Tsai, LH | 1 |
| Callard, RE; Rigley, KP | 1 |
| Hara, M; Harigai, M; Hirose, T; Kawagae, M; Kawakami, M; Kitani, A; Nakamura, H; Suzuki, K | 1 |
| Bahrami, LH; Lenhard, LW; Pandol, SJ; Perkins, PS | 1 |
| Alexander, JS; Patton, WF; Shepro, D; Yoon, MU | 1 |
| Chang, KJ; Chen, KM; Hsieh, KH; Lee, CS; Wang, SM | 2 |
| Agoston, DV; Brenneman, DE; Eiden, LE; Gozes, I | 1 |
| Forrest, MJ; Jewell, ME; Koo, GC; Sigal, NH | 1 |
| Cohan, VL; Gittlen, SW; Kagey-Sobotka, A; Lichtenstein, LM; MacGlashan, DW; Massey, WA; Warner, JA | 1 |
| Natori, K; Onishi, E; Yamazaki, S | 1 |
| Dolan, PW; Malone, DG; Verbsky, JW | 1 |
| Abraham, RT; Abu-Ghazaleh, RI; Gleich, GJ; Kita, H | 1 |
| Asa, SL; Brubaker, PL; Drucker, DJ; Greenberg, GR | 1 |
| Alonso, JL; Campanero, MR; Fresno, M; Pimentel-Muiños, FX; Pivel, JP; Pulido, R; Sánchez-Madrid, F | 1 |
| Cairns, JS; Mainwaring, MS; McCarthy, SA | 1 |
| Rice, CD; Weeks, BA | 1 |
| Donoghue, DJ; Scanes, CG | 1 |
| Beckmann, JD; Claassen, L; Illig, M; Rennard, SI; Rickard, K; Romberger, D; Takizawa, H | 1 |
| Croatto, M; Hamilton, JA; Phillips, WA | 1 |
| Belosevic, M; Daniels, CW | 1 |
| Fain, JN; Pittner, RA | 4 |
| de Groot, RP; de Laat, SW; den Hertog, J; Kruijer, W | 1 |
| Baxter, CS; Leikauf, GD; Smith, JS; Wey, HE | 1 |
| Hsu, SM; Mehta, K; Sanduja, R; Sanduja, SK; Wu, KK; Xu, XM | 1 |
| Fujie, K; Mino, M; Morita, I; Murota, S; Nishihira, J; Sakamoto, W | 1 |
| Annat, J; Derrepas, P; Dutartre, P; Pascal, M | 1 |
| Liu, C; Zhang, Y | 1 |
| Casillas, T; Delicado, EG; Miras-Portugal, MT; Sen, RP | 1 |
| Lucas, M; Solano, F | 1 |
| Cunningham, RK; Zaleski, MB; Zhou, P | 1 |
| Baldinotti, F; Bendinelli, M; Capobianchi, MR; Dianzani, F; Giovannetti, A; Matteucci, D; Soldaini, E | 1 |
| Brezinski, ME; Serhan, CN | 1 |
| Caron, L; Grose, JH; Landry, J; Lebel, M | 1 |
| Kaever, V; Resch, K | 1 |
| Caldwell, CW; Patterson, WP; Yesus, YW | 1 |
| Daculsi, R; Duplan, JF; Guillemain, B; Legrand, E; Vaillier, D | 1 |
| Fischer, M; Strober, S; Van Vlasselaer, P; Zlotnik, A | 1 |
| Agostino, N; Edelson, R; Perez, M; Pernis, B; Yamane, Y | 1 |
| Xiao, D | 2 |
| Andris, F; Dubois, PM; Kaufman, M; Legrand, N; Leo, O; Urbain, J; Van Mechelen, M | 1 |
| Mahé, Y; Pique, C; Scamps, C; Tétaud, C; Tursz, T; Wiels, J | 1 |
| Gao, XH; Habu, S; Nakamura, Y; Nishimura, T; Okumura, K; Takeuchi, Y; Tokuda, Y | 1 |
| Klein-Struckmeier, A; Knüver-Hopf, J; Mohr, H | 1 |
| Celada, A; Maki, RA | 1 |
| Koyasu, S; Sugie, K; Tagaya, Y; Yahara, I; Yodoi, J; Yonehara, S | 1 |
| Ceña, V; Halperin, JI; Klein, DC; Yeandle, S | 1 |
| Häyry, P; Mattila, P; Renkonen, R; Turunen, JP | 1 |
| Elstad, MR; McIntyre, TM; Prescott, SM; Zimmerman, GA | 2 |
| Colman, RF; Colman, RW; Hu, CJ; Puri, RN; Zhou, F | 1 |
| Al, BJ; Gruters, RA; Miedema, F; Otto, SA; Van Lier, RA; Verhoeven, AJ; Verweij, CL | 1 |
| Mate, KE; Rodger, JC | 1 |
| Braquet, P; Ferber, E; Her, E; Reiss, N; Zor, U | 1 |
| Arnon, R; Espinoza, B; Silman, I; Tarrab-Hazdai, R | 1 |
| Axelrod, J; Briley, EM; Felder, CC; Kanterman, RY; Mahan, LC; Monsma, FJ; Sibley, DR | 1 |
| Isom, GE; Rathinavelu, A | 1 |
| Atluru, D; Atluru, S; Jackson, TM | 1 |
| Borunov, EV; Naumov, SA; Shepetkin, IE; Skutina, IL | 1 |
| Harris, RC; Homma, T | 1 |
| Barke, RA; Brady, LJ; Brady, PS | 1 |
| Koyama, S; Leikauf, GD; Rennard, SI; Robbins, RA | 1 |
| Becker, AB; Gerrard, JM; Robertson, C; Saxena, SP | 1 |
| Banga, HS; Feinstein, MB; Halenda, SP | 1 |
| Gyetko, MR; Kole, KL; Simpson, RU; Sitrin, RG | 1 |
| Brash, AR; Hughes, MA | 1 |
| Aiuti, F; Capobianchi, MR; D'Offizi, G; Fanales-Belasio, E; Fiorilli, M; Paganelli, R; Scala, E | 1 |
| Brostrom, CO; Brostrom, MA; Gmitter-Yellen, D; Grandison, LJ; Kuznetsov, G; Prostko, CR; Wong, WL | 1 |
| Radzioch, D; Varesio, L | 1 |
| Belin, D; Blanchard, JM; Collart, MA; Jeanteur, P; Tourkine, N; Vassalli, P | 1 |
| Garcia, MC; Mueller, HW; Rosenthal, MD | 1 |
| Braverman, R; Cooper, HL; Fuldner, R; McDuffie, E | 2 |
| Foreyt, WJ; Laegreid, WW; Leid, RW; Liggitt, HD; Silflow, RM; Taylor, SM | 1 |
| Gilliam, EB; Rosenblatt, HM; Schulam, PG; Shearer, WT; Whelan, JP | 1 |
| Kitaoka, M; Kojima, I; Ogata, E; Takano, K; Tanaka, Y; Teramoto, A | 1 |
| Cybulsky, AV | 1 |
| Gebicke-Haerter, PJ; Hertting, G; Schobert, A | 1 |
| Coffee, KA; Cook, JA; Geisel, J; Halushka, PV; Wise, WC | 1 |
| Park, J; Rikihisa, Y | 1 |
| Yokota, K | 1 |
| Ferrua, B; Konstantinova, I; Limouse, M; Manié, S; Schaffar, L | 1 |
| Ganguly, NK; Khullar, M; Khurana, S; Panigrahi, D; Walia, BN | 1 |
| Baranes, D; Razin, E | 1 |
| Aliño, SF; Almena, A; Barbero, MC; Garcia, M | 1 |
| Arai, K; Arai, N; Miyatake, S; Shlomai, J | 1 |
| Nagai, K; Saitoh, H; Taniguchi, T; Yamada, T; Yamamura, H | 1 |
| Kato, S; Kurimura, T; Naiki, M; Nakajima, K; Osada, Y; Wakamiya, N; Wang, DQ | 1 |
| Brand, K; Hannappel, E; Schöbitz, B | 1 |
| Bultmann, H; Glade, U; Häfker, T; Vicker, MG | 1 |
| Beckman, BS; Broadway, RL; George, WJ; Jeter, JR; Pincus, SM | 1 |
| Chiang, TM; Palazzolo, MR; Solomon, SS | 1 |
| Bertrand, F; Capeau, J; Cherqui, G; Garcia, I; Hermelin, B; Paul, A; Picard, J | 1 |
| Djuric, SW; Fretland, DJ; Gaginella, TS; Levin, S; Shone, RL; Tsai, BS; Walsh, RE; Widomski, DL; Zemaitis, JM | 1 |
| Low, MG; Presky, DH; Shevach, EM | 1 |
| Hafström, I; Kanerud, L; Ringertz, B | 1 |
| Buchan, AM; Campos, RV; Coy, DH; Kwok, YN; Meloche, RM; Pederson, RA | 1 |
| Ishimura, Y; Kizaki, H; Kubota, R; Odaka, C; Okumura, K; Tadakuma, T; Yagita, H | 1 |
| Buchan, AM; Curtis, SB; Meloche, RM | 1 |
| Agea, E; Bertotto, A; Cernetti, C; Gerli, R; Lanfrancone, L; Rambotti, P; Spinozzi, F | 1 |
| Aguilar-Santelises, M; Eriksson, I; Hartzell, P; Jondal, M; McConkey, DJ; Mellstedt, H; Orrenius, S | 1 |
| Bigot, E; Jacques, Y; Naulet, J; Soulillou, JP | 1 |
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| Foda, H; Hymowitz, M; Montana, S; Rollo, EE; Schmidt, CE; Zucker, S | 1 |
| Ha, JH; Jeong, TC; Jun, CD; Kim, SH; Lee, MG; Lee, S; Lee, SG; Lee, SH; Oh, TY; Park, HH; Sohn, DH; Son, HY; Son, JK | 1 |
| An, HJ; Hong, SH; Jeong, HJ; Kim, HM; Kim, HR; Ko, SG; Lee, BH; Moon, PD; Park, SJ; Um, JY | 1 |
| Hong, SH; Jeong, HJ; Kim, HM; Kim, SH; Kim, SY; Shin, HY; Shin, TY; Um, JY | 1 |
| Chae, HS; Cho, SH; Choi, HJ; Choi, JH; Choo, YK; Kang, OH; Kweon, OH; Kwon, DY; Lee, GH; Park, PS; So, HY | 1 |
| Chen, CF; Kuo, YC; Liao, JF; Lin, YL; Liu, CP; Shen, CC; Tsai, WJ; Wu, MH | 1 |
| Banfi, B; Benedyk, M; Bode, G; Kerkhoff, C; Melkonyan, H; Nacken, W; Sopalla, C | 1 |
| Huang, H; Huang, WH; Liu, J; Luo, GX; Peng, DZ; Zheng, JS; Zhou, X | 1 |
| Abe, Y; Han, JK; Isoda, H; Talorete, TP; Yamada, P | 1 |
| Feinmark, SJ; Gor, Y; Karpatkin, S; Nardi, MA; Xu, F | 1 |
| Bark, H; Choi, CH; Kim, SH; Lee, S; Min, YD; Park, EK; Park, HH; Park, JW; Shin, HI; Son, HY | 1 |
| Choi, IY; Hong, SH; Hwang, GS; Jeong, HJ; Kang, TH; Kim, HM; Kim, SJ; Lee, EJ; Lee, JH; Park, JH; Park, SH; Song, YS; Um, JY | 1 |
| Gergely, P; Kovács, I; Sipka, S; Szíjgyártó, Z; Szucs, K; Zákány, R | 1 |
| Liu, ZH; Ma, D; Tai, GX; Zhang, HJ; Zhou, J | 1 |
| Choi, JJ; Jin, M; Kim, DH; Kim, JH; Kim, JS; Park, BK; Song, GY | 1 |
| Fujimiya, M; Imaeda, H; Kashiwagi, K; Ohmori, S; Oyasu, M; Saito, N | 1 |
| Bruckner, G; Brugós, L; Kovács, I; Sipka, S; Szántó, S; Szegedi, G; Szentmiklósi, AJ | 1 |
| Gelb, MH; Gijón, MA; Leslie, CC; Qiu, ZH; Spencer, DM; Tucker, DE | 1 |
| Avendaño, A; Marin, L; Marin, P; Petriz, J; Sales-Pardo, I | 1 |
| Bierhaus, A; Bukulin, M; Fahrenholz, F; Kojro, E; Metz, VV; Nawroth, PP; Postina, R; Roth, A; Zhang, L | 1 |
| Cupanikova, D; Lojek, A; Macickova, T; Nosal, R; Pecivova, J; Pekarova, M | 1 |
| Hong, SH; Kim, CY; Kim, HM; Kim, SD; Lee, EH; Lee, KN; Shin, HY; Shin, TY; Song, YS | 1 |
| Bouwens, EA; Hebbel, RP; Kootstra, NA; Mertens, K; van den Biggelaar, M; Voorberg, J | 1 |
| Chae, HS; Choi, JG; Jang, HJ; Kang, OH; Kim, JH; Kim, YC; Kwon, DY; Lee, YS; Oh, YC; Park, H; Sohn, DH | 1 |
| Chang, IJ; Jeon, H; Kang, SM; Kim, SH; Kim, SY; Leem, KH; Lim, JP; Park, WH; Shin, HY; Shin, TY | 1 |
| Jeon, H; Kim, SH; Kwon, YE; Park, WH; Shin, TY | 1 |
| Go, HY; Hong, MH; Kim, JH; Kim, SH; Ko, SG; Lee, SY; Shin, YC | 1 |
| Lim, KT; Oh, PS; Shim, JU | 1 |
| Furuchi, T; Homma, H; Katane, M; Sekine, M; Suzuki, T | 1 |
| Arruda, LB; Barbosa-Filho, JM; Decoté-Ricardo, D; Lopes, UG; Maria Torres Peçanha, L; Piuvezam, MR; Redner, P; Rocha, JD | 1 |
| Crystal, GJ; Eom, W; Hu, G; Kim, SJ; Saad, MM | 1 |
| Fjaeraa, C; Karlsson, S; Nånberg, E; Wijkander, J | 1 |
| Norante, FA; Taft, AS; Yoshino, TP | 1 |
| Choi, IY; Hong, SH; Jeong, HJ; Kang, IC; Kang, TH; Kim, HM; Kim, JJ; Kim, MH; Kim, NH; Kim, SH; Kim, SJ; Kim, YA; Moon, PD; Myung, NY; Na, HJ; Park, JH; Seo, JU; Seo, YW; Um, JY | 1 |
| Choi, JG; Kang, OH; Kwon, DY; Lee, JH | 1 |
| Akhtar, N; Haqqi, TM; Khan, A; Khan, KA; Rasheed, Z | 1 |
| Han, J; Iijima, R; Isoda, H; Shigemori, H; Yamada, P; Yokota, S | 1 |
| Hong, SH; Jeong, HJ; Kang, TH; Kim, HM; Kim, SJ; Rim, HK; Seo, MJ; Um, JY | 1 |
| Chapman, E; Cross, MJ; Holmes, K; See, V | 1 |
| Chung, WS; Kim, HL; Kim, SJ; Kim, SS; Shin, HJ; Um, JY | 1 |
| Chae, HS; Choi, JG; Han, SH; Kang, OH; Keum, JH; Kim, SB; Kim, YS; Kwon, DY; Mun, SH; Oh, YC; Shin, DW | 1 |
| Kim, HM; Moon, PD | 2 |
| Akamatsu, T; Azlina, A; Hasegawa, T; Hosoi, K; Javkhlan, P; Yao, C | 1 |
| Chowdhury, AA; Ishikawa, T; Jisaka, M; Nagaya, T; Nishimura, K; Rahman, MS; Shono, F; Yokota, K | 1 |
| Cho, IH; Han, NY; Jung, HS; Kim, JH; Lee, MJ; Shin, KW; Sohn, Y | 1 |
| Choi, IH; Kim, HM; Moon, PD | 1 |
| Chae, HS; Chin, YW | 1 |
| Bu, Y; Cho, HS; Cho, IH; Han, NY; Jang, MH; Jung, HS; Kim, SH; Lee, K; Lee, MJ; Shin, KW; Sohn, Y | 1 |
| Bachmann, M; Mühl, H; Pfeilschifter, J; Rudloff, I | 1 |
| Chae, HS; Chin, YW; Khiev, P; Lee, HK; Oh, SR | 1 |
| Choi, H; Gwak, NG; Im, YS; Jung, HS; Kim, MH; Lee, KY; Sohn, Y; Yang, WM | 1 |
| Baik, JE; Chung, DK; Han, SH; Jeon, JH; Kang, SS; Kim, SK; Yun, CH | 1 |
| de Paulis, A; Delfino, G; Di Costanzo, L; Fabbrocini, G; Monfrecola, G | 1 |
| Jeon, DW; Jeong, HJ; Jin, SE; Jun, J; Jung, J; Kim, HM | 1 |
| Jensen, RT; Nuche-Berenguer, B; Sancho, V | 1 |
| Evers, BM; Guo, Z; Wang, Q; Weiss, HL; Zhou, Y | 1 |
| Chander, A; Gerelsaikhan, T; Vasa, PK | 1 |
| Han, YS; Hwang, JK; Kim, MS | 1 |
| Choi, Y; Hwang, JK; Kim, MS | 1 |
| Jeong, HJ; Kim, HM; Moon, PD | 1 |
| Chae, HS; Chin, YW; Lee, HK; Oh, SR; Song, HH | 1 |
| Han, SH; Kang, OH; Keum, JH; Kim, SB; Kim, YG; Kim, YI; Kwon, DY; Lee, YS; Ma, JY; Mun, SH; Oh, YC; Park, CB; Shin, DW | 1 |
| Jha, V; Kaur, T; Mahajan, N; Puri, S; Puri, V; Singla, SK | 1 |
| Wang, HL; Wang, LC; Wei, JW | 1 |
| Han, SH; Kang, OH; Keum, JH; Kim, MR; Kim, SB; Kim, YG; Kim, YI; Kwon, DY; Lee, YS; Mun, SH; Park, CB; Rho, JR; Seo, YS | 1 |
| Han, J; Iijima, R; Isoda, H; Motojima, H; Villareal, MO | 1 |
| Cho, HJ; Han, NY; Jung, HS; Lee, MJ; Sohn, Y | 1 |
| Ahn, EM; Hong, SH; Jung, JW; Kim, SH; Kim, SJ; Lee, GY; Oh, SR; Um, JY | 1 |
| Jang, BH; Jeon, CY; Kim, GJ; Ko, SG; Lee, HJ; Park, JH; Park, SJ; Seo, HS; Shin, YC | 1 |
| Jeong, HJ; Kim, HM; Kim, MJ; Oh, HA; Shin, TY | 1 |
| Han, NR; Jang, JB; Jeong, HJ; Kang, SW; Kim, HM; Moon, PD | 1 |
| Choi, IS; Go, JH; Han, NR; Han, SJ; Jeong, HJ; Kang, SW; Kim, HM; Kim, JS; Kim, MJ; Kim, YS; Lee, BJ; Moon, PD; Nam, SY; Oh, HA; Yoon, S | 1 |
| Daimon, M; Das, G; Itoi, K; Iwasaki, Y; Kageyama, K; Nakada, Y; Niioka, K; Suda, T; Watanuki, Y; Yamagata, S | 1 |
| Han, NR; Jeong, HJ; Kim, HM; Moon, PD | 2 |
| Go, JH; Han, NR; Jeong, HJ; Kim, HM | 1 |
| Balletta, A; Bigalke, H; Gerhard, R; Lorenz, D; Rummel, A; Wegner, F | 1 |
| An, HJ; Choi, JG; Joung, DK; Kang, OH; Kim, SB; Kwon, DY; Mun, SH; Seo, YS; Shin, DW | 1 |
| Jang, SI; Jeon, IH; Jeong, SI; Kang, HJ; Kim, HS; Kim, SJ; Lee, HS | 1 |
| Jeong, HJ; Kim, HM; Kim, MH; Seo, JH | 1 |
| Jeong, KT; Kim, SG; Lee, E; Lee, J; Lee, YJ; Park, HH; Park, NY; Park, YN | 1 |
| Jung, WS; Kim, DH; Kim, ME; Lee, HN; Lee, HW; Lee, JS; Seon, JK; Youn, HY | 1 |
| Ahn, HC; Chae, HS; Chin, YW; Kang, M; Kim, J; Kim, YM; Ryu, KH; Yoo, H; Yoon, KD | 1 |
| Balsalobre, B; Hernández-Godoy, J; Planelles, D | 1 |
| Cao, W; Cao, WX; Feng, ZQ; Guan, X; Guo, JW; Han, QJ; Li, B; Li, YY; Qin, J; Wang, Y; Zhang, HJ; Zhang, MJ; Zhou, J | 1 |
| Choi, IH; Jeong, HJ; Jin, MH; Kim, B; Kim, HM; Lee, MS; Lee, SH; Lee, SY; Roh, SS; Yoou, MS | 1 |
| Calvo, JR; García-Moreno, H; González-Yanes, C; Maldonado, MD | 1 |
| Cheng, RH; Gu, Y; Li, CX; Li, HG; Li, M; Liang, JY; Ling, B; Yao, ZR; Yu, H; Zhang, H | 1 |
| Arnhold, J; Zschaler, J | 1 |
| Chang, NS; Huang, SS; Kuo, HL; Lin, HP; Su, WP; Wei, HL | 1 |
| Chae, HS; Chin, YW; Kim, YM | 1 |
| Barbeau, AM; Gaines, P; O'Fallon, KS; Pelletier, MG; Prata, GN; Szymczak, K | 1 |
| Cao, M; Gao, N; Gong, Y; Hu, CP; Huang, JB; Li, GB; Tang, Q; Wang, QH; Xing, M; Xiong, Y; Zhang, Q; Zhang, R | 1 |
| Asanidze, S; Bernhardt, I; Ghashghaeinia, M; Hanf, B; Kaestner, L; Mohamed, N; Mutua, J; Nguyen, DB; Wagner-Britz, L; Wesseling, MC | 1 |
| Bernuth, HV; Brinkmann, V; Herzig, A; Kenny, EF; Krüger, R; Mondal, S; Muth, A; Thompson, PR; Zychlinsky, A | 1 |
| Han, NR; Jeong, HJ; Kim, HM; Nam, SY; Yoon, KW | 1 |
| Kang, OH; Kim, SA; Kong, R; Kwon, DY; Seo, YS; Shin, DW; Zhou, T | 1 |
| Che, DN; Cho, BO; Jang, SI; Kang, HJ; Kim, YS; Shin, JY | 1 |
| Hu, Q; Jiang, L; Li, Y; Xiao, L | 1 |
| Huang, Y; Ni, YH; Xu, ZM; Yang, XL | 1 |
| Li, Z; Liu, P; Lu, Y; Song, Y; Xie, B; Ye, X | 1 |
| Bruschi, M; Candiano, G; Croia, C; Ghiggeri, G; Migliorini, P; Petretto, A; Pratesi, F | 1 |
| Aye, A; Jeon, YD; Jin, JS; Song, YJ | 1 |
| Li, RX; Qian, ZQ; Yang, HR; Zhu, BJ | 1 |
| Bui, TT; Chai, OH; Fan, YJ; Kim, HT; Lee, SY; Nguyen, TV; Piao, CH; Shin, DU; Shin, HS; Song, CH | 1 |
| Han, NR; Ko, SG; Moon, PD; Park, HJ | 1 |
| Chernysh, A; Inozemtsev, V; Kozlova, E; Lyapunova, S; Sergunova, V; Sherstyukova, E; Vorobjeva, N | 1 |
9 review(s) available for tetradecanoylphorbol acetate and calcimycin
| Article | Year |
|---|---|
Early response pattern analysis of the mitogenic pathway in lymphocytes and fibroblasts.
Topics: Animals; Calcimycin; Calcium; Concanavalin A; Cyclic AMP; DNA; Fibroblasts; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Mitogens; Mitosis; Oncogenes; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Biosynthesis; Protein Kinase C; RNA; Sodium; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
Role of inositol lipid breakdown in the generation of intracellular signals. State of the art lecture.
Topics: Adenosine Diphosphate Ribose; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cytosol; Enzyme Activation; GTP-Binding Proteins; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Molecular Weight; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Protons; Receptors, Cell Surface; Sodium; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1986 |
Inositol phosphates turnover, cytosolic Ca++ and pH: putative signals for the control of cell growth.
Topics: Amiloride; Animals; Calcimycin; Calcium; Calmodulin; Carrier Proteins; Cell Division; Hydrogen-Ion Concentration; Inositol Phosphates; Membrane Lipids; Mitogens; Models, Biological; Phosphatidylinositols; Sodium-Hydrogen Exchangers; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1986 |
Studies and perspectives of protein kinase C.
Topics: Adenosine Triphosphatases; Animals; Blood Platelets; Calcimycin; Calcium-Transporting ATPases; Carrier Proteins; Cation Transport Proteins; Cell Membrane; Cyclic AMP; Diglycerides; Electric Conductivity; Enzyme Activation; Fluorescent Antibody Technique; Isoenzymes; Models, Biological; Phosphatidylinositols; Potassium; Protein Kinase C; Purkinje Cells; Rats; Serotonin; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Protein kinase C and granule release in human platelets.
Topics: Binding Sites; Binding, Competitive; Blood Platelets; Calcimycin; Calcium; Chemical Phenomena; Chemistry, Physical; Cytoplasmic Granules; Diglycerides; Enzyme Activation; Humans; Kinetics; Molecular Conformation; Phorbol Esters; Phospholipids; Phosphoproteins; Phosphorylation; Protein Kinase C; Serotonin; Tetradecanoylphorbol Acetate | 1985 |
Transient induction of c-fos and c-myc in an immediate consequence of growth factor stimulation.
Topics: Animals; Blood; Calcimycin; Cell Line; Cell Transformation, Neoplastic; Colony-Stimulating Factors; Gene Expression Regulation; Growth Substances; Humans; Leukemia, Myeloid, Acute; Macrophages; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate | 1985 |
Phorbol myristate acetate: is a tumor promoter acting as a hormone?
Topics: Animals; Calcimycin; Calcium; Chromosomes; Concanavalin A; Cyclic GMP; DNA; Egtazic Acid; Humans; Myristates; Neoplasms; Potassium; Protein Kinase C; Protons; Sodium; Tetradecanoylphorbol Acetate | 1984 |
Poly-L-arginine and an N-formylated chemotactic peptide act synergistically with lectins and calcium ionophore to induce intense chemiluminescence and superoxide production in human blood leukocytes. Modulation by metabolic inhibitors, sugars, and polyele
Topics: Antimetabolites; Calcimycin; Carbohydrates; Cytochalasin B; Drug Synergism; Electrolytes; Histones; Humans; Inflammation; Lectins; Leukocytes; Ligands; Luminescent Measurements; Luminol; Lysophosphatidylcholines; N-Formylmethionine Leucyl-Phenylalanine; Peptides; Polymyxin B; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Exocytosis induced in neutrophils by chemotactic agents and other stimuli.
Topics: Calcimycin; Carrier Proteins; Cell Compartmentation; Chemotactic Factors; Cytoplasmic Granules; Exocytosis; Humans; In Vitro Techniques; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1983 |
3 trial(s) available for tetradecanoylphorbol acetate and calcimycin
| Article | Year |
|---|---|
Arachidonic acid metabolism in normal human alveolar macrophages: stimulus specificity for mediator release and phospholipid metabolism, and pharmacologic modulation in vitro and in vivo.
Topics: Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Dexamethasone; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Macrophage Activation; Macrophages; Phosphatidylcholines; Phosphatidylinositols; Pulmonary Alveoli; Radioimmunoassay; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1990 |
Relevance of acrosome function in the evaluation of semen in vitro fertilizing ability.
Topics: Acrosome; Calcimycin; Discriminant Analysis; Female; Fertilization in Vitro; Humans; Infertility, Female; Infertility, Male; Male; Semen; Sperm Capacitation; Sperm Count; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; Tetradecanoylphorbol Acetate; Treatment Outcome | 1995 |
Mechanisms of rapid induction of interleukin-22 in activated T cells and its modulation by cyclosporin a.
Topics: Autoimmune Diseases; Calcimycin; Calcium Ionophores; Carcinogens; Cyclosporine; Female; Gene Expression Regulation; Humans; I-kappa B Kinase; Immunosuppressive Agents; Interleukin-22; Interleukins; Jurkat Cells; Lymphocyte Activation; Male; Response Elements; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors | 2012 |
1907 other study(ies) available for tetradecanoylphorbol acetate and calcimycin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Role of Ca2+ and Mg2+ in some human neutrophil functions as indicated by ionophore A23187.
Topics: Anti-Bacterial Agents; Calcimycin; Calcium; Cations, Divalent; Chemotaxis; Cyclic GMP; Cytoplasmic Granules; Humans; Magnesium; Neutrophils; Tetradecanoylphorbol Acetate | 1976 |
Intracellular mediation of lymphokine action: mimicry of migration inhibitory factor (MIF) action by phorbol myristate acetate (PMA) and the ionophore A23187.
Topics: Animals; Anti-Bacterial Agents; Calcimycin; Calcium; Cell Migration Inhibition; Cyclic AMP; Fluorescent Antibody Technique; Guinea Pigs; Luminescent Measurements; Macrophage Migration-Inhibitory Factors; Macrophages; Male; Microtubules; Phorbols; Polymers; Superoxides; Tetradecanoylphorbol Acetate; Tubulin; Vinblastine | 1979 |
Role of secretory events in modulating human neutrophil chemotaxis.
Topics: Binding Sites; Calcimycin; Cell Adhesion; Cell Migration Inhibition; Chemotaxis, Leukocyte; Concanavalin A; Cytoplasmic Granules; Exocytosis; Humans; In Vitro Techniques; Muramidase; Neutrophils; Peptides; Tetradecanoylphorbol Acetate | 1978 |
Phorbol esters differentially regulate the expression of insulin-like growth factor-binding proteins in endometrial carcinoma cells.
Topics: Adenocarcinoma; Alkaloids; Blotting, Northern; Calcimycin; Carrier Proteins; Cell Division; Cycloheximide; Endometrial Neoplasms; Enzyme Activation; Female; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Proteins; Kinetics; Protein Kinase C; RNA, Messenger; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1992 |
An unusual T-cell surface phenotype in vivo correlates with the failure to proliferate and produce IL-2 in vitro in a patient with common variable immunodeficiency.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Adrenal Cortex Hormones; Adult; Antigen-Presenting Cells; Antigens, CD; Antigens, CD1; Antigens, Differentiation; Calcimycin; CD3 Complex; Cell Death; Common Variable Immunodeficiency; HLA-DR Antigens; Humans; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Male; Membrane Glycoproteins; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
Phorbol esters induce nitric oxide synthase activity in rat hepatocytes. Antagonism with the induction elicited by lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carcinogens; Cells, Cultured; Cyclic GMP; Diglycerides; Enzyme Induction; Kinetics; Lipopolysaccharides; Liver; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate | 1992 |
Failure of c-myc gene expression in B cells of some patients with common variable immunodeficiencies.
Topics: Adult; B-Lymphocytes; Blotting, Northern; Calcimycin; Calcium; CD3 Complex; CD4 Antigens; CD8 Antigens; Child; Common Variable Immunodeficiency; Dose-Response Relationship, Drug; Female; Gene Expression; Genes, myc; Humans; Immunoglobulin A; Immunoglobulin Fab Fragments; Immunoglobulin G; Immunoglobulin M; Interleukin-2; Lymphocyte Activation; Male; RNA; Staphylococcus aureus; Tetradecanoylphorbol Acetate | 1992 |
Inhibitory effect of human syncytiotrophoblast plasma membrane vesicles on Jurkat cells activated by phorbol ester and calcium ionophore.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcimycin; Calcium; CD3 Complex; Cell Membrane; Colforsin; Cyclic AMP; Cytoplasm; Down-Regulation; Female; Humans; Interleukin-2; Lymphocyte Activation; Pregnancy; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate; Trophoblasts; Tumor Cells, Cultured | 1992 |
Human decidua is a target tissue for bradykinin and kallikrein: phosphoinositide hydrolysis accompanies arachidonic acid release in uterine decidua cells in vitro.
Topics: Arachidonic Acids; Bradykinin; Calcimycin; Cells, Cultured; Decidua; Dinoprost; Female; Fibroblasts; Humans; Hydrolysis; Interleukin-1; Kallikreins; Kinetics; Phosphatidylinositols; Pregnancy; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Synergistic effects of cyclic AMP and Ca2+ ionophore A23187 on de novo synthesis of histidine decarboxylase in mastocytoma P-815 cells.
Topics: Animals; Bucladesine; Calcimycin; Calcium; Culture Media; Cyclic AMP; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Histidine Decarboxylase; Isoquinolines; Mast-Cell Sarcoma; Mice; Protein Kinase C; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Lipoxin generation by human megakaryocyte-induced 12-lipoxygenase.
Topics: Arachidonate 12-Lipoxygenase; Calcimycin; Cell Differentiation; Cell Line; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene A4; Leukotrienes; Megakaryocytes; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate | 1992 |
Insight into the nature and site of oxygen-centered free radical generation by endothelial cell monolayers using a novel spin trapping technique.
Topics: Animals; Calcimycin; Calcium; Cathepsin G; Cathepsins; Cells, Cultured; Deferoxamine; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Free Radicals; Hydrogen Peroxide; In Vitro Techniques; Lung; Oxygen; Pancreatic Elastase; Paraquat; Phagocytes; Serine Endopeptidases; Swine; Tetradecanoylphorbol Acetate | 1992 |
Regulation of phospholipase A2 activation and arachidonic acid metabolism in an interleukin-3-dependent macrophage-like cell line.
Topics: Animals; Arachidonic Acids; Biological Transport; Bone Marrow; Bone Marrow Cells; Calcimycin; Calcium; Cell Fractionation; Cells, Cultured; Dinoprostone; Eicosanoids; Enzyme Activation; Hydrogen-Ion Concentration; Interleukin-3; Leukotriene B4; Macrophages; Mice; Mice, Inbred CBA; Phospholipases A; Phospholipases A2; Protein Kinase C; Tetradecanoylphorbol Acetate; Tritium | 1992 |
Effects of staurosporine, PMA and A23187 on human melanocyte cultures with dibutyryl cyclic AMP.
Topics: Adult; Alkaloids; Bucladesine; Calcimycin; Cells, Cultured; Humans; Male; Melanocytes; Membrane Glycoproteins; Microscopy, Fluorescence; Monophenol Monooxygenase; Oxidoreductases; Protein Kinase C; Proteins; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Regulation of c-fos, c-jun and jun-B messenger ribonucleic acids by angiotensin-II and corticotropin in ovine and bovine adrenocortical cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenocorticotropic Hormone; Angiotensin II; Animals; Blotting, Northern; Calcimycin; Cattle; Cell Differentiation; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Gene Expression Regulation; Glucocorticoids; Protein Kinase C; Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Sheep; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Phorbol esters stimulate and inhibit Cl- secretion by different mechanisms in a colonic cell line.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Bumetanide; Calcimycin; Cell Line; Chlorides; Colforsin; Colon; Cyclic AMP; Iodides; Potassium; Rubidium; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Altered regulation of arachidonic acid metabolism by SV40 immortalized human urothelial cells.
Topics: Arachidonic Acid; Aspirin; Bradykinin; Calcimycin; Cell Line, Transformed; Dinoprostone; Diterpenes; Microsomes; Prostaglandin-Endoperoxide Synthases; Simian virus 40; Terpenes; Tetradecanoylphorbol Acetate; Urinary Bladder | 1992 |
The insulin-like growth factor I receptor is overexpressed in psoriatic epidermis, but is differentially regulated from the epidermal growth factor receptor.
Topics: Antibodies, Monoclonal; Calcimycin; Epidermal Growth Factor; Epidermis; ErbB Receptors; Humans; Insulin-Like Growth Factor I; Keratinocytes; Precipitin Tests; Protein Kinases; Psoriasis; Receptors, Cell Surface; Receptors, Somatomedin; Tetradecanoylphorbol Acetate | 1992 |
Endothelins belong to the assortment of mast cell-derived and mast cell-bound cytokines.
Topics: Animals; Base Sequence; Bone Marrow Cells; Calcimycin; Cells, Cultured; Cytokines; Endothelins; Mast Cells; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, Cell Surface; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
Functional implications of cAMP and Ca2+ on prostaglandin I2 and thromboxane A2 synthesis by human endothelial cells.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Caffeine; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Epoprostenol; Humans; Kinetics; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1992 |
Proteinkinase C beta-isoform triggers the formation of prostanoids and superoxide in liver macrophages.
Topics: Animals; Calcimycin; Cells, Cultured; Dinoprostone; Isoenzymes; Liver; Macrophages; Male; Prostaglandins; Protein Kinase C; Rats; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
The second messenger pathway for germ cell-mediated stimulation of Sertoli cells.
Topics: Animals; Bucladesine; Calcimycin; Cells, Cultured; Cyclic AMP; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Follicle Stimulating Hormone; Heat-Shock Proteins; Male; Phosphoproteins; Phosphorylation; Rats; Rats, Inbred Strains; Second Messenger Systems; Sertoli Cells; Tetradecanoylphorbol Acetate | 1992 |
The direct involvement of cAMP-dependent protein kinase in the regulation of collagen synthesis by parathyroid hormone (PTH) and PTH-related peptide in osteoblast-like osteosarcoma cells (UMR-106).
Topics: Animals; Bucladesine; Calcimycin; Cell Line; Collagen; Cyclic AMP; Ionomycin; Kinetics; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proline; Protein Kinases; Proteins; Rats; Tetradecanoylphorbol Acetate; Thionucleotides; Tritium | 1992 |
Sodium fluoride provokes gonadotrope desensitization to gonadotropin-releasing hormone (GnRH) and gonadotrope sensitization to A23187: evidence for multiple G proteins in GnRH action.
Topics: Animals; Azides; Bucladesine; Calcimycin; Cells, Cultured; Egtazic Acid; Female; Gonadotropin-Releasing Hormone; GTP-Binding Proteins; Inositol Phosphates; Kinetics; Luteinizing Hormone; Models, Biological; Pituitary Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, LHRH; Sodium Azide; Sodium Cyanide; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1992 |
Multifactorial regulation of prostaglandin synthesis in preovulatory goldfish ovarian follicles.
Topics: Animals; Bucladesine; Calcimycin; Chloroquine; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Female; Goldfish; Melitten; Ovarian Follicle; Ovary; Phospholipases A; Phospholipases A2; Prostaglandins; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Characterization of oxytocin receptors in rabbit amnion involved in the production of prostaglandin E2.
Topics: Amnion; Animals; Arginine Vasopressin; Binding, Competitive; Calcimycin; Cell Membrane; Cells, Cultured; Decidua; Dinoprostone; Female; Kinetics; Oxytocin; Pregnancy; Rabbits; Receptors, Angiotensin; Receptors, Oxytocin; Receptors, Vasopressin; Tetradecanoylphorbol Acetate; Uterus | 1992 |
Reversible uncoupling of phosphoinositidase C activation and steroidogenesis in cultured bovine adrenocortical zfr cells.
Topics: Acetylcholine; Adrenal Cortex; Adrenocorticotropic Hormone; Angiotensin II; Animals; Calcimycin; Cattle; Cells, Cultured; Enzyme Activation; Hydrocortisone; Kinetics; Phosphoric Diester Hydrolases; Tetradecanoylphorbol Acetate | 1992 |
The effects of the phospholipase A2 inhibitors aristolochic acid and PGBx on A23187-stimulated mobilization of arachidonate in human neutrophils are overcome by diacylglycerol or phorbol ester.
Topics: Arachidonic Acid; Aristolochic Acids; Calcimycin; Diglycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenanthrenes; Phosphatidate Phosphatase; Phospholipase D; Phospholipases A; Phospholipases A2; Polymers; Prostaglandins B; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
Rapid ultrastructural changes in the dense tubular system following platelet activation.
Topics: Blood Platelets; Calcimycin; Calcium; Egtazic Acid; Endoplasmic Reticulum; Fluorescent Dyes; Glucose-6-Phosphatase; Humans; In Vitro Techniques; Kinetics; Microscopy, Electron; Platelet Activation; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Evidence that activation of protein kinase-C can stimulate 1,25-dihydroxyvitamin D3 secretion by rat proximal tubules.
Topics: Alkaloids; Analysis of Variance; Animals; Calcimycin; Calcitonin; Calcitriol; Cyclic AMP; Enzyme Activation; In Vitro Techniques; Kidney Cortex; Kidney Tubules, Proximal; Kinetics; Male; Parathyroid Hormone; Peptide Fragments; Perfusion; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Teriparatide; Tetradecanoylphorbol Acetate | 1992 |
Age-related changes in the mechanisms of LHRH-stimulated LH release from pituitary cells in vitro.
Topics: Aging; Analysis of Variance; Animals; Buserelin; Calcimycin; Calcium Channels; Cells, Cultured; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Nifedipine; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, LHRH; Tetradecanoylphorbol Acetate | 1992 |
Ca2+ uptake by endoplasmic reticulum of renal cortex. I. Ionic requirements and regulation in vitro.
Topics: Adenosine Triphosphate; Animals; Barium; Bucladesine; Calcimycin; Calcitriol; Calcium; Calcium Radioisotopes; Calmodulin; Cations, Divalent; Cobalt; Dogs; Endoplasmic Reticulum; Female; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Ionomycin; Kidney Cortex; Magnesium; Male; Manganese; Microscopy, Electron; Subcellular Fractions; Tetradecanoylphorbol Acetate; Ultracentrifugation | 1992 |
Regulation of 1 alpha, 25-dihydroxyvitamin D3 synthesis in macrophages from arthritic joints by phorbol ester, dibutyryl-cAMP and calcium ionophore (A23187).
Topics: Arthritis; Arthritis, Gouty; Arthritis, Rheumatoid; Bucladesine; Calcimycin; Calcitriol; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Macrophages; Synovial Fluid; Tetradecanoylphorbol Acetate | 1992 |
Activation of intracellular signalling pathways induces secretion of mucin by isolated rat gastric mucosal cells.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Gastric Mucosa; Kinetics; Mucins; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Protein kinase C involved in zymosan-induced release of arachidonic acid and superoxide but not in calcium ionophore-elicited arachidonic acid release or formation of prostaglandin E2 from added arachidonate.
Topics: Alkaloids; Animals; Arachidonic Acids; Blotting, Western; Calcimycin; Carbazoles; Cells, Cultured; Dinoprostone; Indole Alkaloids; Kupffer Cells; Male; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Diacylglycerol rather than Ca2+ mediates GnRH inhibition of FSH induced steroidogenesis in ovarian granulosa cells.
Topics: Animals; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Diethylstilbestrol; Diglycerides; Drug Implants; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Granulosa Cells; Multienzyme Complexes; Phosphatidylinositols; Progesterone Reductase; Rats; Silicone Elastomers; Stearic Acids; Steroid Isomerases; Steroids; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Regulation of ornithine decarboxylase by parathyroid hormone in osteoblastic cell systems.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Northern; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Dinoprost; Enzyme Induction; Hormones; Ornithine Decarboxylase; Osteoblasts; Parathyroid Hormone; Peptide Fragments; Prostaglandins E; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
A new, one-step assay on whole cell suspensions for peroxidase secretion by human neutrophils and eosinophils.
Topics: Calcimycin; Cell Separation; Eosinophil Peroxidase; Eosinophils; Humans; Indicators and Reagents; L-Lactate Dehydrogenase; Neutrophils; Oligopeptides; Peroxidase; Peroxidases; Platelet Activating Factor; Reference Values; Spectrophotometry; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Identification of positive and negative placenta-specific basal elements and a cyclic adenosine 3',5'-monophosphate response element in the human gene for P450scc.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Base Sequence; Calcimycin; Cholesterol Side-Chain Cleavage Enzyme; Choriocarcinoma; Colforsin; Cyclic AMP; Cycloheximide; DNA; Ethanol; Female; Gene Expression Regulation, Enzymologic; Genes; Humans; Molecular Sequence Data; Organ Specificity; Placenta; Pregnancy Proteins; Promoter Regions, Genetic; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Sequence Deletion; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Uterine Neoplasms | 1992 |
Reactive oxygen species and human spermatozoa: analysis of the cellular mechanisms involved in luminol- and lucigenin-dependent chemiluminescence.
Topics: Acridines; Calcimycin; Fluorescent Dyes; Humans; In Vitro Techniques; Luminescent Measurements; Luminol; Male; Peroxidase; Reactive Oxygen Species; Spermatozoa; Tetradecanoylphorbol Acetate | 1992 |
Calcium ionophore treatment impairs the sterol-mediated suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, 3-hydroxy-3-methylglutaryl-coenzyme A synthase, and farnesyl diphosphate synthetase.
Topics: Alkyl and Aryl Transferases; Calcimycin; Calcium; Cell Line; Cycloheximide; Dactinomycin; DNA; Drug Antagonism; Gene Expression Regulation, Enzymologic; Geranyltranstransferase; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxymethylglutaryl-CoA Synthase; Precipitin Tests; Protein Kinase C; RNA, Messenger; Sterols; Tetradecanoylphorbol Acetate; Transferases | 1992 |
Discriminatory effects of protein kinase inhibitors and calcium ionophore on endothelial ICAM-1 induction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Calcimycin; Cell Adhesion Molecules; Cell Survival; Cytokines; Drug Synergism; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Ionomycin; Isoquinolines; Lipopolysaccharides; Piperazines; Protein Biosynthesis; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Molecular characterization of interleukin 12.
Topics: Amino Acid Sequence; Amino Acids; B-Lymphocytes; Binding Sites; Calcimycin; Cell Line; Drug Synergism; Glycosylation; Humans; Interleukin-12; Interleukin-2; Interleukins; Lymphocyte Activation; Lymphocytes; Macromolecular Substances; Molecular Sequence Data; Peptide Fragments; Phytohemagglutinins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tryptophan | 1992 |
Interaction of ethanol with signal transduction mechanisms mediating growth hormone release by rat pituitary cells in vitro.
Topics: Animals; Bucladesine; Calcimycin; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Ethanol; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; RNA, Messenger; Signal Transduction; Somatostatin; Tetradecanoylphorbol Acetate | 1992 |
The effects of interferon-beta on phorbol ester or calcium ionophore-induced intercellular adhesion molecule-I expression in epidermal carcinoma cells.
Topics: Calcimycin; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cell Line; Enzyme Activation; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interferon-beta; Keratinocytes; Protein Kinase C; Second Messenger Systems; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Interaction between phosphoinositide turnover system and cyclic AMP pathway for the secretion of pancreastatin and somatostatin from QGP-1N cells.
Topics: Adenoma, Islet Cell; Atropine; Bucladesine; Calcimycin; Carbachol; Cell Line; Chromogranin A; Colforsin; Cyclic AMP; Drug Synergism; Humans; Kinetics; Pancreatic Hormones; Pancreatic Neoplasms; Phosphatidylinositols; Somatostatin; Tetradecanoylphorbol Acetate; Theophylline; Tumor Cells, Cultured | 1992 |
Duck lymphocytes--V. Transformation responses to phorbol ester and calcium ionophore.
Topics: Animals; Biotransformation; Calcimycin; Cell Separation; Cells, Cultured; Drug Synergism; Ducks; Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
The cytotoxic process of CD4 Th1 clones.
Topics: Animals; Calcimycin; Cations, Divalent; CD4-Positive T-Lymphocytes; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; DNA Damage; Mice; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Phosphorylation and activation of tyrosine hydroxylase in PC18 cells: a cell line derived from rat pheochromocytoma PC12 cells.
Topics: Animals; Bucladesine; Calcimycin; Colforsin; Cyclic AMP; Dexamethasone; Enzyme Activation; PC12 Cells; Peptide Mapping; Phosphorylation; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1992 |
A novel in vitro method for investigating cartilage degradation.
Topics: Animals; Calcimycin; Cartilage, Articular; Cattle; Cells, Cultured; Densitometry; Glycosaminoglycans; Humans; Male; Nasal Septum; Neutrophils; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Murine B7 antigen provides an efficient costimulatory signal for activation of murine T lymphocytes via the T-cell receptor/CD3 complex.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Ly; Antigens, Surface; B7-1 Antigen; Blotting, Northern; Calcimycin; CD3 Complex; CD4-Positive T-Lymphocytes; CHO Cells; Cricetinae; Glycolipids; Glycosylphosphatidylinositols; Interleukin-2; Lymphocyte Activation; Mice; Phosphatidylinositols; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; Signal Transduction; Tetradecanoylphorbol Acetate; Thy-1 Antigens; Transfection; Up-Regulation | 1992 |
Lymphocyte activation and regulation of three adhesion molecules with supposed function in homing: LECAM-1 (MEL-14 antigen), LPAM-1/2 (alpha 4-integrin) and CD44 (Pgp-1).
Topics: Animals; Calcimycin; Cell Adhesion Molecules; Cell Movement; Concanavalin A; Down-Regulation; Endothelium, Vascular; Female; Integrins; Interleukin-8; L-Selectin; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Receptors, Lymphocyte Homing; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1992 |
Heparin suppresses specific second messenger pathways for protooncogene expression in rat vascular smooth muscle cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blotting, Northern; Bucladesine; Calcimycin; Cell Cycle; Cells, Cultured; DNA; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation; Genes, fos; Genes, myc; Heparin; Muscle, Smooth, Vascular; Protein Kinase C; Proto-Oncogenes; Rats; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1992 |
Tumor-promoting phorbol ester down-regulates the androgen induction of prostate-specific antigen in a human prostatic adenocarcinoma cell line.
Topics: Alkaloids; Antigens, Neoplasm; Biomarkers, Tumor; Calcimycin; Colforsin; Dose-Response Relationship, Drug; Down-Regulation; Humans; Male; Nandrolone; Phorbols; Prostate-Specific Antigen; Prostatic Neoplasms; RNA, Messenger; Staurosporine; Testosterone Congeners; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Modulation of human basophil histamine release by protein kinase C inhibitors differs with secretagogue and with inhibitor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Basophils; Calcimycin; Glyceryl Ethers; Histamine Release; Humans; Indoles; Isoquinolines; Maleimides; Mannitol; Palmitoylcarnitine; Piperazines; Polymyxin B; Protein Kinase C; Sphingosine; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate | 1992 |
Protoporphyrin and long-wave ultraviolet light modulate metabolic events in rat peritoneal mast cells.
Topics: Animals; Calcimycin; Calcium; Cytosol; Histamine Release; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Prostaglandin D2; Protoporphyrins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1992 |
A collection of mRNA species that are inducible in the RAW 264.7 mouse macrophage cell line by gamma interferon and other agents.
Topics: Animals; beta 2-Microglobulin; Calcimycin; Cell Division; Cell Line; Chromosome Mapping; Cloning, Molecular; Culture Media; Cytokines; Gene Expression Regulation; Interferon-gamma; Interferons; Lipopolysaccharides; Macrophages; Metallothionein; Mice; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factors | 1992 |
Charcot-Leyden crystal protein in the degranulation and recovery of activated basophils.
Topics: Antigens, Differentiation, B-Lymphocyte; Basophils; Calcimycin; Cell Degranulation; Fluorescent Antibody Technique; Glycoproteins; Histamine Release; Humans; In Vitro Techniques; Lysophospholipase; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate | 1992 |
Ca(2+)-dependent and Ca(2+)-independent mechanisms modulate whole-cell cationic currents in human neutrophils.
Topics: Adenine Nucleotides; Bucladesine; Calcimycin; Calcium; Cations; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Ion Channels; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Potassium; Sodium; Tetradecanoylphorbol Acetate | 1992 |
Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2.
Topics: Alleles; Amino Acid Sequence; Animals; Base Sequence; Calcimycin; Culture Techniques; Gene Expression Regulation; Hematopoietic Cell Growth Factors; Mice; Molecular Sequence Data; Protein Processing, Post-Translational; RNA Splicing; RNA, Messenger; Stem Cell Factor; Tetradecanoylphorbol Acetate | 1992 |
Decreased G-CSF and IL-3 production and gene expression from mononuclear cells of newborn infants.
Topics: Adult; Bacterial Infections; Calcimycin; Fetal Blood; Gene Expression; Granulocyte Colony-Stimulating Factor; Humans; In Vitro Techniques; Infant, Newborn; Interleukin-3; Leukocytes, Mononuclear; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Cell Line; Colonic Neoplasms; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Kinetics; Membrane Proteins; Piperazines; Protein Kinase C; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
Components of the protein kinase C pathway induce Ia expression after injection into macrophages.
Topics: Alkaloids; Animals; Calcimycin; Diglycerides; Histocompatibility Antigens Class II; In Vitro Techniques; Interferon-gamma; Isoquinolines; Macrophages; Mice; Mice, Inbred C3H; Microinjections; Naphthalenes; Phospholipases A; Phospholipases A2; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins p21(ras); Signal Transduction; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Cyclic AMP and calcium regulate at a transcriptional level the expression of the CD7 leukocyte differentiation antigen.
Topics: Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Bucladesine; Calcimycin; Calcium; Cell Nucleus; Cells, Cultured; Cyclic AMP; Cycloheximide; Humans; Kinetics; Lymphocyte Activation; Phytohemagglutinins; RNA; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
Influence of CGS 9343B, an inhibitor of calmodulin activity, on histamine release from isolated rat mast cells.
Topics: Animals; Benzimidazoles; Calcimycin; Calmodulin; Histamine Release; In Vitro Techniques; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1992 |
IL-2 regulation of soluble IL-2 receptor levels following thermal injury.
Topics: Adult; Aged; Antigens, CD; Burns; Calcimycin; Calcium; CD5 Antigens; Colforsin; Humans; In Vitro Techniques; Indomethacin; Interleukin-1; Interleukin-2; Interleukin-3; Lymphocyte Activation; Middle Aged; Monocytes; Receptors, Interleukin-2; Solubility; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Thapsigargin defines the roles of cellular calcium in secretagogue-stimulated enzyme secretion from pancreatic acini.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Bombesin; Calcimycin; Calcium; Calcium-Transporting ATPases; Carbachol; Cytoplasm; Fura-2; In Vitro Techniques; Kinetics; Male; Pancreas; Rats; Rats, Sprague-Dawley; Secretin; Sincalide; Spectrometry, Fluorescence; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vasoactive Intestinal Peptide | 1992 |
de novo synthesis of calmodulin binding protein in substance P-induced steroidogenesis in bovine adrenocortical cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Calcimycin; Calcium; Calmodulin-Binding Proteins; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Hydrocortisone; Leucine; Substance P; Tetradecanoylphorbol Acetate | 1992 |
Actions of two native GnRHs and protein kinase C modulators on goldfish pituitary cells. Studies on intracellular calcium levels and gonadotropin release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Biological Transport; Calcimycin; Calcium; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Fluorescence; Fura-2; Goldfish; Gonadotropin-Releasing Hormone; Pituitary Gland; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil | 1992 |
Evidence for a novel mechanism of activation of phospholipase D by endothelin-1 in neuroblastoma cells.
Topics: Animals; Calcimycin; Endothelins; Enzyme Activation; Indoles; Kinetics; Neuroblastoma; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Regulation of prostacyclin production by [Ca2+]i and protein kinase C in aortic smooth muscle cells.
Topics: Animals; Aorta; Arginine Vasopressin; Calcimycin; Calcium; Cytosol; Enzyme Activation; Epoprostenol; Muscle, Smooth, Vascular; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1992 |
Comparison of diglyceride production from choline-containing phosphoglycerides in human neutrophils stimulated with N-formylmethionyl-leucylphenylalanine, ionophore A23187 or phorbol 12-myristate 13-acetate.
Topics: Calcimycin; Cells, Cultured; Choline; Diglycerides; Drug Interactions; Ethanol; Glycerophosphates; Humans; Hydrolysis; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Propranolol; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Gold complexes and activation of human polymorphonuclear leukocytes. Dissociation of changes in membrane potential and oxidative burst.
Topics: Auranofin; Calcimycin; Cell Survival; Concanavalin A; Drug Interactions; Gold Sodium Thiomalate; Humans; Luminescent Measurements; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate | 1992 |
Multiple effects of staurosporine, a kinase inhibitor, on thymocyte functions. Comparison with the effect of tyrosine kinase inhibitors.
Topics: Alkaloids; Animals; Benzylidene Compounds; Calcimycin; Carbazoles; Cell Division; Cells, Cultured; Concanavalin A; Dose-Response Relationship, Drug; Indole Alkaloids; Mice; Mice, Inbred BALB C; Nitriles; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thymus Gland; Tyrphostins | 1992 |
Effect of ozone on platelet-activating factor production in phorbol-differentiated HL60 cells, a human bronchial epithelial cell line (BEAS S6), and primary human bronchial epithelial cells.
Topics: Bronchi; Calcimycin; Cell Differentiation; Cells, Cultured; Chromatography, Thin Layer; Epithelial Cells; Epithelium; Humans; Ozone; Platelet Activating Factor; Radioimmunoassay; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Angiotensin II-induced protein phosphorylation in the hypertrophic heart of the Dahl rat.
Topics: Angiotensin II; Animals; Calcimycin; Cardiomegaly; Cell Separation; Drug Resistance; Electrophoresis; Ionomycin; Methionine; Muscle Proteins; Myocardium; Phosphoproteins; Phosphorylation; Rats; Rats, Inbred Strains; Sodium Chloride; Tetradecanoylphorbol Acetate | 1992 |
Augmented expression and release of nonspecific cross-reacting antigens (NCAs), members of the CEA family, by human neutrophils during cell activation.
Topics: Antigens, Neoplasm; Antigens, Surface; Calcimycin; Cell Adhesion Molecules; Cell Degranulation; Cell Membrane; Humans; In Vitro Techniques; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1992 |
Inhibition of lymphocyte proliferation by bovine trophoblast protein-1 (type I trophoblast interferon) and bovine interferon-alpha I1.
Topics: Animals; Calcimycin; Cattle; Female; Interferon Type I; Interleukin-2; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mitogens; Pregnancy; Pregnancy Proteins; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1992 |
Interleukin-4 (IL-4) receptor expression on human T cells is affected by different intracellular signaling pathways and by IL-4 at transcriptional and posttranscriptional level.
Topics: Calcimycin; Calcium; Cells, Cultured; Concanavalin A; Cycloheximide; Cyclosporine; Dactinomycin; Gene Expression Regulation; Humans; Interleukin-4; Receptors, Interleukin-4; Receptors, Mitogen; RNA Processing, Post-Transcriptional; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
Phosphatidylinositol hydrolysis by phospholipase A2 and C activities in human peripheral blood neutrophils.
Topics: Arachidonic Acid; Calcimycin; Calcium Chloride; Cell Membrane; Chromatography, Thin Layer; Cytosol; Deoxycholic Acid; Detergents; Edetic Acid; Humans; Kinetics; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Octoxynol; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Polyethylene Glycols; Stearic Acids; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Differential effects of phorbol esters on proliferation and calcyclin expression in human endometrial carcinoma cells.
Topics: Adenocarcinoma; Alkaloids; Calcimycin; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Division; Cycloheximide; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; S100 Calcium Binding Protein A6; S100 Proteins; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Uterine Neoplasms | 1992 |
Comparison of stimulated tissue factor expression by brain microvascular endothelial cells from normotensive (WKY) and hypertensive (SHR) rats.
Topics: Animals; Brain; Calcimycin; Endothelium, Vascular; Hypertension; Interleukin-1; Lipopolysaccharides; Microcirculation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate; Thrombin; Thromboplastin; Tumor Necrosis Factor-alpha | 1992 |
[Influence of an activator of protein kinase C (TPA) and a calcium-mobilizing agonist (A 23187) on zinc metabolism in the rat].
Topics: Alkaline Phosphatase; Animals; Blood Glucose; Body Weight; Calcimycin; Creatinine; Eating; Liver; Male; Metallothionein; Organ Size; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Urea; Zinc | 1992 |
Novel 1-(pyridylphenyl)-1-phenyl-2-imidazolylethanols with topical antiinflammatory activity.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Calcimycin; Cyclooxygenase Inhibitors; Dermatitis; Edema; Imidazoles; Lipoxygenase Inhibitors; Male; Mice; Molecular Structure; Phospholipases A; Pyridines; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1992 |
Heat shock induces apoptosis in mouse thymocytes and protects them from glucocorticoid-induced cell death.
Topics: Animals; Calcimycin; Cell Death; Dexamethasone; DNA Damage; Heat-Shock Proteins; Hot Temperature; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate; Thymus Gland | 1992 |
Deciduogenic effects of mediators of the polyphosphatidylinositol pathway in pseudopregnant mice.
Topics: Animals; Calcimycin; Concanavalin A; Decidua; Female; Mice; Phosphatidylinositols; Pseudopregnancy; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate | 1992 |
Expression of c-fos and c-myc oncogenes in the P388D1 murine macrophage line treated by immunomodulators: absence of direct correlation with DNA synthesis.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Animals; Calcimycin; Cell Line; DNA; Gene Expression; Genes, fos; Genes, myc; Macrophage Colony-Stimulating Factor; Macrophages; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1992 |
Effects of calcium ions on the germination of Sporothrix schenckii conidia.
Topics: Calcimycin; Calcium Chloride; Cobalt; Culture Media; Fungal Proteins; RNA, Fungal; Spores, Fungal; Sporothrix; Tetradecanoylphorbol Acetate | 1992 |
Cell response kinetics: the phenomenon of supercooperativity in aggregation of human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Calcimycin; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Tetradecanoylphorbol Acetate; Thimerosal | 1992 |
Effect of benzylidene derivative (novel antirheumatic agent) on chondrocyte metabolism.
Topics: Animals; Benzaldehydes; Calcimycin; Cartilage; Catechols; Cells, Cultured; Interleukin-1; Metalloendopeptidases; Proteoglycans; Rabbits; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate | 1992 |
Differential effects of the calcium ionophore A23187 and the phorbol ester PMA on lymphocyte proliferation.
Topics: Animals; Calcimycin; Cells, Cultured; Kinetics; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mitogens; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
The roles of protein kinase C and intracellular Ca2+ in the secretion of von Willebrand factor from human vascular endothelial cells.
Topics: Adenosine Triphosphate; Alkaloids; Calcimycin; Calcium; Cations, Divalent; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Humans; Indoles; Maleimides; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; von Willebrand Factor | 1992 |
Effect of T cell activation on lymphocyte-endothelial cell adherence and the role of VLA-4 in the rat.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Cell Adhesion; Concanavalin A; Endothelium, Vascular; Interferon-gamma; Interleukin-2; Kinetics; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; Rats; Rats, Inbred Strains; Receptors, Antigen, T-Cell; Receptors, Very Late Antigen; Recombinant Proteins; T-Lymphocytes; Temperature; Tetradecanoylphorbol Acetate | 1992 |
An 11-base-pair DNA sequence motif apparently unique to the human interleukin 4 gene confers responsiveness to T-cell activation signals.
Topics: Animals; Base Sequence; Calcimycin; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation; Genes; Humans; Interleukin-2; Interleukin-4; Lymphocyte Activation; Mice; Molecular Sequence Data; Oligodeoxyribonucleotides; Regulatory Sequences, Nucleic Acid; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Transcription Factors | 1992 |
TcR-alpha mRNA accumulation does not dictate cell surface TcR/CD3 expression.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Cell Line; Cells, Cultured; Cycloheximide; Down-Regulation; Flow Cytometry; Gene Expression Regulation; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Interleukin-2; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
HLA-DR genes are silenced in human trophoblasts and stimulation of signal transduction pathways does not circumvent interferon-gamma unresponsiveness.
Topics: Calcimycin; Cholera Toxin; Colforsin; Female; Genes, MHC Class II; HLA-DR Antigens; Humans; Interferon-gamma; Ionomycin; Placenta; Platelet Activating Factor; Pregnancy; Receptors, Immunologic; Receptors, Interferon; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Trophoblasts; Virulence Factors, Bordetella | 1992 |
Mechanism of neutrophil-induced xanthine dehydrogenase to xanthine oxidase conversion in endothelial cells: evidence of a role for elastase.
Topics: Animals; Calcimycin; Cell Cycle; Cycloheximide; Endothelium, Vascular; In Vitro Techniques; Ionomycin; Neutrophils; Oxygen; Pancreas; Pancreatic Elastase; Rats; Reperfusion Injury; Tetradecanoylphorbol Acetate; Xanthine Dehydrogenase; Xanthine Oxidase | 1992 |
Role of protein kinase C in the regulation of prostaglandin synthesis in human endothelium.
Topics: Aequorin; Affinity Labels; Alkaloids; Arachidonic Acid; Calcimycin; Calcium; Cations, Divalent; Down-Regulation; Egtazic Acid; Endothelium, Vascular; Enzyme Activation; Epoprostenol; Humans; Inositol Phosphates; Luminescent Measurements; Protein Kinase C; Radioimmunoassay; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Study on the mechanism of Giardia lamblia induced diarrhoea in mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Biological Transport; Calcimycin; Calcium; Chlorides; Diarrhea; Giardia lamblia; Intestinal Mucosa; Isoquinolines; Mice; Piperazines; Protein Kinase C; Sodium; Tetradecanoylphorbol Acetate | 1992 |
Sequential incorporation of 3H- and 14C-arachidonic acid during 24 h in rabbit colonic explants cultured in vitro.
Topics: Animals; Arachidonic Acid; Calcimycin; Cell Compartmentation; Colon; Culture Techniques; Dinoprostone; Intestinal Mucosa; Lipid Metabolism; Male; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipases A; Rabbits; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Control of thyroid secretion: effects of stimulators of protein kinase C, thyrotropin, and calcium mobilization on secretion of iodinated compounds from sheep thyroid cells.
Topics: Alkaloids; Animals; Calcimycin; Calcium; Cells, Cultured; Inositol Phosphates; Iodine Radioisotopes; Protein Kinase C; Protein Kinases; Sheep; Staurosporine; Tetradecanoylphorbol Acetate; Thyroglobulin; Thyroid Gland; Thyroid Hormones; Thyrotropin | 1992 |
Triggering by ATP of product release by mucous granules of the land slug Ariolimax columbianus.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcimycin; Cytoplasmic Granules; Dinoprostone; Electric Stimulation; Ethylmaleimide; Furosemide; Ibuprofen; Indomethacin; Kinetics; Microscopy, Electron; Mollusca; Mucous Membrane; Nigericin; Pertussis Toxin; Tetradecanoylphorbol Acetate; Verapamil; Virulence Factors, Bordetella | 1992 |
Platelet-activating factor-stimulated protein tyrosine phosphorylation and eicosanoid synthesis in rat Kupffer cells. Evidence for calcium-dependent and protein kinase C-dependent and -independent pathways.
Topics: Animals; Blotting, Western; Calcimycin; Calcium; Down-Regulation; Egtazic Acid; Eicosanoids; Electrophoresis, Polyacrylamide Gel; Gallic Acid; Kupffer Cells; Phosphorylation; Platelet Activating Factor; Precipitin Tests; Protein Kinase C; Radioimmunoassay; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine | 1992 |
Stimulatory and inhibitory effects of 1,25-dihydroxyvitamin D3 on thymocyte mitogenesis induced by phorbol ester and calcium ionophore.
Topics: Calcimycin; Calcitriol; Calcium; Interleukin-2; Lymphocyte Activation; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
Stimulation of phosphatidic acid synthesis in bovine aortic endothelial cells in response to activation of P2-purinergic receptors.
Topics: Animals; Aorta; Calcimycin; Calcium; Cattle; Endothelium, Vascular; Enzyme Activation; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1992 |
Secretion of carboxypeptidase E from cultured astrocytes and from AtT-20 cells, a neuroendocrine cell line: implications for neuropeptide biosynthesis.
Topics: Animals; Astrocytes; Calcimycin; Carboxypeptidase H; Carboxypeptidases; Cells, Cultured; Colforsin; Isoproterenol; Methionine; Mice; Neuropeptides; Neurosecretory Systems; Pituitary Gland; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Time Factors; Vasoactive Intestinal Peptide | 1992 |
IL-12 receptor. II. Distribution and regulation of receptor expression.
Topics: Animals; Calcimycin; CD4 Antigens; CD8 Antigens; Cell Line; Cells, Cultured; Humans; Interleukin-2; Lymphocyte Activation; Lymphocytes; Phenotype; Phytohemagglutinins; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate | 1992 |
The effects of a single intraoperative immersion in various chemical agents and electromagnetic field exposure on onlay bone grafts to the facial skeleton.
Topics: Animals; Bone and Bones; Bone Transplantation; Calcimycin; Colforsin; Electromagnetic Fields; Facial Bones; Glycerophosphates; Male; Rabbits; Tetradecanoylphorbol Acetate | 1992 |
Perforin expression in human peripheral blood mononuclear cells. Definition of an IL-2-independent pathway of perforin induction in CD8+ T cells.
Topics: Base Sequence; Calcimycin; Calcium; CD8 Antigens; Cell Adhesion; Cyclosporine; Emetine; Gene Expression; Granzymes; Humans; Interleukin-2; Leukocytes, Mononuclear; Membrane Glycoproteins; Membrane Proteins; Molecular Sequence Data; Oligodeoxyribonucleotides; Perforin; Pore Forming Cytotoxic Proteins; RNA, Messenger; Serine Endopeptidases; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Actions of phorbol esters on levels of cAMP in cholera toxin-treated chief cells from guinea pig stomach.
Topics: Animals; Calcimycin; Calmodulin; Carbachol; Cholera Toxin; Gastric Mucosa; Guinea Pigs; Imidazoles; In Vitro Techniques; Kinetics; Male; Phorbol 12,13-Dibutyrate; Phorbols; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate | 1992 |
Interleukins modulate glucocorticoid-induced thymocyte apoptosis.
Topics: Animals; Calcimycin; Cell Death; Cell Differentiation; Cells, Cultured; Dexamethasone; DNA Replication; Interleukins; Mice; Mice, Inbred C3H; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1992 |
Proliferation of shark leukocytes.
Topics: Animals; Calcimycin; Cell Division; Cells, Cultured; Leukocytes; Sharks; Tetradecanoylphorbol Acetate | 1992 |
Defining the role of protein kinase c in calcium-ionophore-(A23187)-mediated activation of phospholipase A2 in pulmonary endothelium.
Topics: Animals; Arachidonic Acid; Calcimycin; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Phospholipases A; Phospholipases A2; Protein Kinase C; Pulmonary Artery; Sphingosine; Tetradecanoylphorbol Acetate | 1992 |
[The role of signal transduction systems in the regulation of production and secretion of TA-4 by cultured cervical epidermoid carcinoma cells (CaSki)].
Topics: Antigens, Neoplasm; Calcimycin; Carcinoma, Squamous Cell; Cholera Toxin; Female; Humans; Serpins; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1992 |
Intracellular Ca2+ mobilization and not calcium influx promotes phorbol ester-stimulated thromboxane A2 synthesis in human platelets.
Topics: Alkaloids; Blood Platelets; Calcimycin; Calcium; Chromatography, High Pressure Liquid; Cytosol; Drug Synergism; Humans; Membrane Lipids; Phorbol 12,13-Dibutyrate; Phospholipids; Platelet Aggregation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1992 |
Regulation of phosphatidic acid phosphohydrolase activity during stimulation of human polymorphonuclear leukocytes.
Topics: Calcimycin; Gene Expression Regulation, Enzymologic; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidate Phosphatase; Signal Transduction; Subcellular Fractions; Substrate Specificity; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Defective lipopolysaccharide-induced production of both interleukin 1 alpha and interleukin 1 beta by A/J mouse macrophages is posttranscriptionally regulated.
Topics: Animals; Calcimycin; Cells, Cultured; Gene Expression Regulation; Indomethacin; Interleukin-1; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Proteins secreted from the early ovine conceptus block the action of prostaglandin F2 alpha on large luteal cells.
Topics: Animals; Calcimycin; Chromatography, Gel; Dinoprost; Female; Hot Temperature; Interferon Type I; Luteal Cells; Molecular Weight; Pregnancy; Pregnancy Proteins; Progesterone; Sheep; Tetradecanoylphorbol Acetate | 1992 |
Hm1 muscarinic cholinergic receptor internalization requires a domain in the third cytoplasmic loop.
Topics: Amino Acid Sequence; Binding Sites; Calcimycin; Carbachol; Cells, Cultured; Cytoplasm; Humans; Kidney; Molecular Sequence Data; Mutation; N-Methylscopolamine; Phosphorylation; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives; Sequence Alignment; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella | 1992 |
Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Arachidonic Acid; Calcimycin; Calcium; CHO Cells; Cricetinae; Cytosol; Enzyme Activation; Epidermal Growth Factor; In Vitro Techniques; Phospholipases A; Phospholipases A2; Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
Regulation of inhibin beta B-subunit mRNA expression in rat Sertoli cells: consequences for the production of bioactive and immunoreactive inhibin.
Topics: Alkaloids; Animals; Calcimycin; Calcium; Cells, Cultured; Centrifugation, Density Gradient; Inhibins; Male; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Messenger; Sertoli Cells; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
The effect of serine and thiol protease inhibitors on the chemiluminescence of human neutrophils in investigations in vitro.
Topics: Calcimycin; Cysteine Proteinase Inhibitors; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate; Tosylarginine Methyl Ester; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine; Zymosan | 1992 |
Protein kinase C as a mediator of high density lipoprotein receptor-dependent efflux of intracellular cholesterol.
Topics: Apolipoprotein A-I; Apolipoproteins A; Biological Transport; Calcimycin; Carrier Proteins; Cell Membrane; Cells, Cultured; Cholesterol; Diglycerides; Down-Regulation; Enzyme Activation; Humans; Lipoproteins, HDL; Protein Kinase C; Receptors, Cell Surface; Receptors, Lipoprotein; RNA-Binding Proteins; Skin; Sphingosine; Tetradecanoylphorbol Acetate | 1991 |
The effect of PGF2 alpha on parathyroid hormone-stimulated cyclic AMP production in mouse osteoblastic cell, MC3T3E1.
Topics: Animals; Calcimycin; Cell Line; Cell Membrane; Cyclic AMP; Dinoprost; Kinetics; Mice; Osteoblasts; Parathyroid Hormone; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Signal transduction pathways in the induction of HLA class I antigen expression on Huh 6 cells by interferon-gamma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Calmodulin; Carcinoma, Hepatocellular; Cell Line; Cyclic CMP; Histocompatibility Antigens Class I; Humans; Interferon-gamma; Isoquinolines; Liver Neoplasms; Piperazines; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Metabolic activation of chlorpromazine by stimulated human polymorphonuclear leukocytes. Induction of covalent binding of chlorpromazine to nucleic acids and proteins.
Topics: Biotransformation; Calcimycin; Chlorpromazine; Chromatography, High Pressure Liquid; DNA Damage; Humans; In Vitro Techniques; Luminescent Measurements; Neutrophils; Nucleic Acids; Peroxidase; Proteins; Tetradecanoylphorbol Acetate | 1991 |
Vitamin E inhibits PGE2 and O2- production in rat peritoneal macrophages.
Topics: Animals; Calcimycin; Calcium; Dinoprostone; Dose-Response Relationship, Drug; Fura-2; Macrophages; Male; Peritoneum; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate; Vitamin E | 1991 |
Regulation of secretion in cultured tracheal serous cells by protein kinases A and C.
Topics: Animals; Calcimycin; Chondroitin Sulfate Proteoglycans; Cyclic AMP; Isoproterenol; Protein Kinase C; Protein Kinases; Serous Membrane; Sphingosine; Tetradecanoylphorbol Acetate; Trachea | 1991 |
Effects of the phorbol ester phorbol 12-myristate 13-acetate (PMA) on islet-cell responsiveness.
Topics: Animals; Calcimycin; Calcium; Glucose; Immunoblotting; Inositol; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nitrendipine; Phosphatidylinositols; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate; Tolbutamide | 1991 |
Alterations of B lymphocyte Fc gamma R II expression and ligand binding capacity induced by various activators.
Topics: Animals; Antigen-Antibody Complex; Antigens, Differentiation; B-Lymphocytes; Calcimycin; Calcium; Cells, Cultured; Cycloheximide; Emetine; Female; Histocompatibility Antigens Class II; Immunoglobulin mu-Chains; In Vitro Techniques; Interleukin-4; Lymphocyte Activation; Mice; Mice, Inbred DBA; Receptors, Antigen, B-Cell; Receptors, Fc; Receptors, IgG; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Inhibition by nilvadipine of ischemic and carrageenan paw edema as well as of superoxide radical production from neutrophils and xanthine oxidase.
Topics: Animals; Calcimycin; Carrageenan; Edema; Free Radicals; Ischemia; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred Strains; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nifedipine; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1991 |
Stimulation of GRP78 gene transcription by phorbol ester and cAMP in GH3 pituitary cells. The accommodation of protein synthesis to chronic deprivation of intracellular sequestered calcium.
Topics: Calcimycin; Calcium; Cell Line; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Pituitary Gland; Protein Biosynthesis; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Receptor modulation and early signal transduction events in cytotoxic T lymphocytes inactivated by sensitive target cells.
Topics: Antigenic Modulation; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Calcimycin; Calcium; Cytotoxicity, Immunologic; Down-Regulation; Granzymes; HLA Antigens; Humans; Immunity, Cellular; In Vitro Techniques; Interleukin-2; Lymphocyte Function-Associated Antigen-1; Phosphatidylinositols; Serine Endopeptidases; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1991 |
Activation of protein kinase-C inhibits vitamin D receptor gene expression.
Topics: Alkaloids; Animals; Blotting, Northern; Blotting, Southern; Calcimycin; Cell Division; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Gene Expression Regulation, Enzymologic; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C modulates cAMP content in proximal tubular cells: role of phosphodiesterase inhibition.
Topics: Angiotensin II; Animals; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Enzyme Activation; Kidney Tubules, Proximal; Norepinephrine; Parathyroid Hormone; Phosphodiesterase Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Inhibitory effects of ethanol on the calcium-dependent potentiation of vasoactive intestinal peptide-stimulated cAMP and cGMP accumulation in rat pinealocytes.
Topics: Animals; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Male; Pineal Gland; Potassium; Rats; Rats, Inbred Strains; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1991 |
Immunoregulatory effects of sizofiran (SPG) on lymphocytes and polymorphonuclear leukocytes.
Topics: Antibody-Dependent Cell Cytotoxicity; Calcimycin; Cytokines; Cytotoxicity, Immunologic; Humans; Immunity, Innate; In Vitro Techniques; Killer Cells, Natural; Lymphocyte Subsets; Lymphocytes; Neutrophils; Protein Kinase C; Respiratory Burst; Sizofiran; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Cholecystokinin inhibits phosphatidylcholine synthesis via a Ca(2+)-calmodulin-dependent pathway in isolated rat pancreatic acini. A possible mechanism for diacylglycerol accumulation.
Topics: Alkaloids; Animals; Bombesin; Bucladesine; Calcimycin; Calcium; Calmodulin; Carbachol; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Diglycerides; In Vitro Techniques; Kinetics; Male; Nucleotidyltransferases; Pancreas; Phosphatidylcholines; Protein Kinase C; Rats; Rats, Inbred Strains; Secretin; Sincalide; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tritium | 1991 |
Stimulation of macrophage urokinase expression by polyanions is protein kinase C-dependent and requires protein and RNA synthesis.
Topics: Animals; Anions; Bucladesine; Calcimycin; Cell Line; Cycloheximide; Dactinomycin; Gene Expression; Kinetics; Macrophages; Mice; Molecular Weight; Polysaccharides; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator | 1991 |
Evidence for a role of protein kinase-C in His-D-Trp-Ala-Trp-D-Phe-Lys-NH2-induced growth hormone release from rat primary pituitary cells.
Topics: Amino Acid Sequence; Animals; Calcimycin; Colforsin; Cyclic AMP; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Molecular Sequence Data; Oligopeptides; Phloretin; Pituitary Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1991 |
Roles of actin filaments and three second-messenger systems in short-term regulation of chick dorsal root ganglion neurite outgrowth.
Topics: Actins; Animals; Calcimycin; Calcium; Chick Embryo; Colforsin; Cryopreservation; Cyclic AMP; Cytochalasins; Cytoskeleton; Ganglia, Spinal; Microscopy, Electron; Neurons; Protein Kinase C; Pseudopodia; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1991 |
The prostaglandin paradox: additive inhibition of neutrophil function by aspirin-like drugs and the prostaglandin E1 analog misoprostol.
Topics: Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcimycin; Calcium; Cell Aggregation; Cyclic AMP; Depression, Chemical; Drug Synergism; Glucuronidase; Humans; Indomethacin; Misoprostol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins; Sodium Salicylate; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Basal activation of protein kinase C in rat alveolar macrophages: implications for arachidonate metabolism.
Topics: Alkaloids; Animals; Arachidonic Acids; Basal Metabolism; Calcimycin; Cells, Cultured; Enzyme Activation; Female; Leukotriene B4; Macrophages, Alveolar; Peritoneum; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Inhibition of prostaglandin E2 and superoxide anion production in rat peritoneal macrophages by the calcium antagonists nifedipine and nisoldipine.
Topics: Animals; Arachidonic Acid; Calcimycin; Dinoprostone; Fura-2; In Vitro Techniques; Macrophages; Male; Nifedipine; Nisoldipine; Peritoneal Cavity; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Changes in beta-adrenergic receptor distribution on immunocytes during differentiation: an analysis of T cells and macrophages.
Topics: Animals; Calcimycin; Cell Differentiation; Cell Line; Concanavalin A; Cortisone; Cyclic AMP; Macrophages; Mice; Mice, Inbred BALB C; Radioligand Assay; Receptors, Adrenergic, beta; Second Messenger Systems; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Retinoids inhibit the respiratory burst and degranulation of stimulated human polymorphonuclear leukocytes.
Topics: Calcimycin; Cyclooxygenase Inhibitors; Cytoplasmic Granules; Diterpenes; Humans; Lipoxygenase Inhibitors; Luminescent Measurements; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Retinyl Esters; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A; Zymosan | 1991 |
Platelet-activating factor may participate in signal transduction processes in rabbit leukocytes.
Topics: Animals; Arachidonic Acid; Azepines; Blood Platelets; Calcimycin; Chloroquine; Female; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Triazoles | 1991 |
Expression of the rat prothymosin alpha gene during T-lymphocyte proliferation and liver regeneration.
Topics: Animals; Blotting, Northern; Calcimycin; Cell Cycle; Gene Expression; Histones; Hydroxyurea; Liver Regeneration; Lymphocyte Activation; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Protein Precursors; Rats; Rats, Inbred Strains; RNA, Messenger; S Phase; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymosin; Time Factors | 1991 |
Altered interleukin-2 secretion in patients with primary fibromyalgia syndrome.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; Concanavalin A; Fibromyalgia; Humans; Interleukin-2; Lymphocyte Activation; Lymphocyte Depletion; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1991 |
T-lymphocyte activation pathways in alcoholic liver disease.
Topics: Adult; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Calcimycin; CD2 Antigens; CD3 Complex; Cell Division; Female; Humans; Interleukins; Liver Diseases, Alcoholic; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; Receptors, Antigen, T-Cell; Receptors, Immunologic; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Inhibitory effects of histamine H1 receptor blocking drugs on metabolic activations of neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Biotransformation; Calcimycin; Cell Survival; Histamine H1 Antagonists; Humans; In Vitro Techniques; Leukotrienes; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Signal transduction systems in growth hormone-releasing hormone and somatostatin release from perifused rat hypothalamic fragments.
Topics: Animals; Calcimycin; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Growth Hormone-Releasing Hormone; Hypothalamus; In Vitro Techniques; Kinetics; Male; Perfusion; Protein Kinase C; Rats; Rats, Inbred Strains; Signal Transduction; Somatostatin; Tetradecanoylphorbol Acetate | 1991 |
Activation of high-affinity uptake of glutamate by phorbol esters in primary glial cell cultures.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Binding, Competitive; Calcimycin; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Glutamates; Glutamic Acid; Isoquinolines; Kinetics; Neuroglia; Neurons; Piperazines; Tetradecanoylphorbol Acetate | 1991 |
Characteristics and kinetics of proopiomelanocortin mRNA expression by human leucocytes.
Topics: Blotting, Northern; Calcimycin; Corticotropin-Releasing Hormone; Gene Expression Regulation; Humans; Interleukin-1; Interleukin-2; Leukocytes; Lymphocyte Activation; Lymphocyte Subsets; Neutrophils; Poly A; Pro-Opiomelanocortin; RNA, Messenger; Tetradecanoylphorbol Acetate | 1991 |
Carbamylcholine and phorbol esters desensitize muscarinic receptors by different mechanisms in rat pancreatic acini.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Calcimycin; Carbachol; Dose-Response Relationship, Drug; Down-Regulation; Gallic Acid; Isoquinolines; Male; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Secretory Rate; Tetradecanoylphorbol Acetate | 1990 |
Extracellular calcium regulates expression of the gene for atrial natriuretic factor.
Topics: Animals; Atrial Natriuretic Factor; Calcimycin; Calcium; Calcium Channel Blockers; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Extracellular Space; Gene Expression Regulation; Myocardium; Nucleic Acid Hybridization; Precipitin Tests; RNA; RNA, Complementary; Tetradecanoylphorbol Acetate | 1990 |
The involvement of protein kinase C in exocytosis in mast cells.
Topics: Animals; Calcimycin; Diglycerides; Drug Synergism; Exocytosis; Histamine Release; Kinetics; Male; Mast Cells; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Regulation of insulin-like growth factor I gene expression in the human macrophage-like cell line U937.
Topics: Calcimycin; Cell Line; Gene Expression Regulation; Humans; Insulin-Like Growth Factor I; Macrophages; Protein Biosynthesis; RNA; RNA, Messenger; Somatomedins; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Carbachol desensitizes pancreatic enzyme secretion by downregulation of receptors.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Bombesin; Calcimycin; Carbachol; Cycloheximide; Down-Regulation; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Pancreas; Receptors, Cell Surface; Sincalide; Substance P; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1990 |
Protein kinase C-mediated regulation of the expression of CD14 and CD11/CD18 in U937 cells.
Topics: Antigens, CD; Antigens, Differentiation; Antigens, Differentiation, Myelomonocytic; Calcimycin; Calcium; Calmodulin; CD11 Antigens; CD18 Antigens; Cell Differentiation; Humans; Leukemia, Myeloid; Lipopolysaccharide Receptors; Protein Kinase C; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Synergistic action of calcium ionophore A23187 and protein kinase C activator bryostatin 1 on human B cell activation and proliferation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibody Formation; B-Lymphocytes; Bryostatins; Calcimycin; Cell Cycle; Cyclosporins; DNA; Enzyme Activation; Humans; In Vitro Techniques; Isoquinolines; Lactones; Lymphocyte Activation; Macrolides; Piperazines; Protein Kinase C; RNA; Tetradecanoylphorbol Acetate | 1990 |
Functional differentiation of human cytotoxic T lymphocytes in the presence of FK 506 and CyA.
Topics: Anti-Bacterial Agents; Calcimycin; Cell Differentiation; Cyclosporins; Cytotoxicity, Immunologic; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Phytohemagglutinins; T-Lymphocytes, Cytotoxic; Tacrolimus; Tetradecanoylphorbol Acetate | 1990 |
Control of plasminogen activator activity in the thecal layer of the largest preovulatory follicle in the hen ovary.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Chickens; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Female; Luteinizing Hormone; Osmolar Concentration; Ovarian Follicle; Ovary; Ovulation; Plasminogen Activators; Prostaglandins; Tetradecanoylphorbol Acetate; Theca Cells | 1990 |
Activation-induced cell death in T cell hybridomas is due to apoptosis. Morphologic aspects and DNA fragmentation.
Topics: Aurintricarboxylic Acid; Calcimycin; Cell Survival; Concanavalin A; Cycloheximide; Cyclosporins; Dactinomycin; DNA Damage; Hybridomas; Lymphocyte Activation; Microscopy, Electron; Protein Biosynthesis; RNA; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Cyclosporin A rapidly inhibits mediator release from human basophils presumably by interacting with cyclophilin.
Topics: Antibodies, Anti-Idiotypic; Basophils; Bryostatins; Calcimycin; Calcium; Carrier Proteins; Cyclosporins; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Lactones; Macrolides; Peptidylprolyl Isomerase; SRS-A; Tetradecanoylphorbol Acetate | 1990 |
Tyrosine-specific protein phosphorylation during activation of human neutrophils.
Topics: Blotting, Western; Calcimycin; Cytosol; Humans; In Vitro Techniques; Leukotriene B4; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Phosphotyrosine; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Down-regulation of CD5 mRNA in B-chronic lymphocytic leukemia cells by differentiation-inducing agents.
Topics: Aged; Antigens, CD; Antigens, Differentiation; Bryostatins; Calcimycin; CD5 Antigens; Cell Differentiation; Female; Gene Expression Regulation, Neoplastic; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Male; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
The role of protein kinase C in histamine secretion from mast cells.
Topics: Animals; Biological Transport; Calcimycin; Calcium; Diglycerides; Histamine Release; Male; Mast Cells; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, B-Lymphocyte; Calcimycin; Calcium; Calcium Chloride; Cell Line; Histamine Release; Immunoglobulin E; Kinetics; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, Fc; Receptors, IgE; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Subpopulations of CD4+ cells in lpr/lpr mice: differences in expression of T cell receptor/CD3 complex and proliferative responses.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Blotting, Northern; Calcimycin; CD3 Complex; CD4 Antigens; CD4-Positive T-Lymphocytes; Flow Cytometry; Gene Expression; Interleukin-2; Leukocyte Common Antigens; Lupus Erythematosus, Systemic; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Mutant Strains; Receptors, Antigen, T-Cell; RNA, Messenger; Tetradecanoylphorbol Acetate | 1990 |
Protein tyrosine phosphorylation in rabbit peritoneal neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminoquinolines; Animals; Calcimycin; Calcium; Immunoblotting; Isoquinolines; Leukotriene B4; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Piperazines; Protein Kinase Inhibitors; Rabbits; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Transmembrane ion conductance in human B lymphocyte activation.
Topics: 4-Aminopyridine; B-Lymphocytes; Calcimycin; Calcium; Cell Cycle; Diltiazem; Electric Conductivity; Humans; Immunoglobulin mu-Chains; In Vitro Techniques; Ion Channels; Lymphocyte Activation; Membrane Potentials; Potassium Channels; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Tetraethylammonium Compounds; Verapamil | 1990 |
Human P450scc gene transcription is induced by cyclic AMP and repressed by 12-O-tetradecanoylphorbol-13-acetate and A23187 through independent cis elements.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Base Sequence; Calcimycin; Cell Line; Cholesterol Side-Chain Cleavage Enzyme; Codon; Cyclic AMP; Genes; Humans; Kinetics; Mice; Molecular Sequence Data; Plasmids; Protein Biosynthesis; Restriction Mapping; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1990 |
Production of interleukin 6 from human liver cell lines: production of interleukin 6 is not concurrent with the production of alpha-fetoprotein.
Topics: Adolescent; Adult; alpha-Fetoproteins; Blotting, Northern; Calcimycin; Cell Line; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Interleukin-6; Liver; Male; Middle Aged; RNA; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1990 |
Cognate interactions between helper T cells and B cells. IV. Requirements for the expression of effector phase activity by helper T cells.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; B-Lymphocytes; Calcimycin; CD3 Complex; Cell Cycle; Cell Membrane; Concanavalin A; Interleukin-4; Lymphocyte Activation; Lymphocyte Cooperation; Mice; Mice, Inbred DBA; Receptors, Antigen, T-Cell; RNA; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Proliferative potential of murine peritoneal mast cells after degranulation induced by compound 48/80, substance P, tetradecanoylphorbol acetate, or calcium ionophore A23187.
Topics: Animals; Calcimycin; Cell Degranulation; Cell Division; In Vitro Techniques; Mast Cells; Mice; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Skin; Substance P; Tetradecanoylphorbol Acetate | 1990 |
Evidence that Ca2(+)-dependent activation of airway epithelia Cl- channels is not dependent on phosphorylation.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Calcimycin; Calcium; Cells, Cultured; Chloride Channels; Cyclic AMP; Cytosol; Dogs; Epithelium; Iodides; Ion Channels; Kinetics; Membrane Proteins; Muscle, Smooth; Phosphorylation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Trachea | 1990 |
Expression of normal and cystic fibrosis phenotypes by continuous airway epithelial cell lines.
Topics: Antigens, Polyomavirus Transforming; Base Sequence; Biomarkers; Blood Proteins; Bradykinin; Calcimycin; Calgranulin A; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Chloride Channels; Chlorides; Colforsin; Cystic Fibrosis; Epithelial Cells; Epithelium; Genotype; Humans; Ion Channels; Keratins; Membrane Potentials; Membrane Proteins; Molecular Sequence Data; Nasal Mucosa; Oligonucleotide Probes; Phenotype; Polymerase Chain Reaction; Reference Values; Retroviridae; Simian virus 40; Tetradecanoylphorbol Acetate; Theophylline | 1990 |
Inhibition of histamine, leukotriene C4/D4, and thromboxane B2 release from human leukocytes and human chopped lung mast cells by the allergic mediator release inhibitor, CI-949.
Topics: Basophils; Calcimycin; Dose-Response Relationship, Drug; Histamine Antagonists; Histamine Release; Humans; Immunoglobulin E; Indoles; Lung; Mast Cells; SRS-A; Tetradecanoylphorbol Acetate; Tetrazoles; Thromboxane B2 | 1990 |
Effects of FK 506 and cyclosporine on T-cell activation: integrin-mediated adhesion of T cells, proliferation, and maturation of cytotoxic T cells.
Topics: Anti-Bacterial Agents; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; CD4-Positive T-Lymphocytes; Cell Adhesion; Cell Adhesion Molecules; Cyclosporins; Cytotoxicity, Immunologic; Fibronectins; Humans; Immunosuppressive Agents; In Vitro Techniques; Integrins; Intercellular Adhesion Molecule-1; Laminin; Lymphocyte Activation; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Tacrolimus; Tetradecanoylphorbol Acetate | 1991 |
Differential modulation by N4, 2'-O-dibutyryl cytidine 3':5'-cyclic monophosphate of neutrophil activation.
Topics: Butyrates; Calcimycin; Calcium; Cyclic CMP; Growth Substances; Hexachlorocyclohexane; Humans; Lymphocyte Activation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1991 |
Overexpression of c-fos in a human pre-B cell acute lymphocytic leukemia derived cell line, SMS-SB.
Topics: Base Sequence; Blotting, Southern; Burkitt Lymphoma; Calcimycin; Cell Line; Cyclic GMP; DNA; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Inhibition of B cell proliferation with anti-CD19 monoclonal antibodies: anti-CD19 antibodies do not interfere with early signaling events triggered by anti-IgM or interleukin 4.
Topics: Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antigens, CD; Antigens, CD19; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Calcimycin; Calcium; Cyclic AMP; DNA; Humans; In Vitro Techniques; Interleukin-4; Lymphocyte Activation; Phorbol Esters; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Receptors, Antigen, B-Cell; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Sphingosine inhibition and promotion of histamine release from isolated rat mast cells.
Topics: Animals; Calcimycin; Calcium; Drug Interactions; Histamine Release; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Sphingosine; Tetradecanoylphorbol Acetate | 1990 |
Discrete association of CD3 and CD4 molecules in T-cell stimulation acting through the autologous mixed lymphocyte reaction and the CD3/T-cell receptor complex in human autoreactive T-cell clones.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Autoantigens; Calcimycin; CD3 Complex; CD4 Antigens; Clone Cells; Epitopes; Flow Cytometry; Humans; Immunophenotyping; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Intracellular mechanisms involved in short-term regulation of net protein synthesis in pancreatic acini.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Amylases; Animals; Calcimycin; Carbachol; DNA Probes; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzymes; Isoquinolines; Lipase; Nucleic Acid Hybridization; Pancreas; Pancreatic Elastase; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Cytokeratin filament modulation in pulmonary microvessel endothelial cells by vasoactive agents and culture confluency.
Topics: Animals; Bradykinin; Calcimycin; Capillaries; Cattle; Cells, Cultured; Contact Inhibition; Cytochalasin B; Egtazic Acid; Endothelium, Vascular; Intermediate Filaments; Keratins; Lung; Tetradecanoylphorbol Acetate; Vimentin | 1991 |
Second messenger pathways mediating chicken luteinizing hormone secretion from dispersed pituitary cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Arachidonic Acids; Calcimycin; Calcium; Carcinogens; Chickens; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Pituitary Gland; Protein Kinase C; Second Messenger Systems; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transforming Growth Factor alpha | 1991 |
Tumoricidal activity of interferon-r activated peripheral monocytes in colorectal cancer patients.
Topics: Aged; Aminoquinolines; Calcimycin; Calcium; Colorectal Neoplasms; Cytotoxicity, Immunologic; Enzyme Activation; Female; Humans; In Vitro Techniques; Interferons; Lipopolysaccharides; Macrophage Activation; Male; Middle Aged; Monocytes, Activated Killer; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Spontaneous electrical activity regulates vasoactive intestinal peptide expression in dissociated spinal cord cell cultures.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Actins; Action Potentials; Animals; Blotting, Northern; Calcimycin; Cells, Cultured; Embryo, Mammalian; Ganglia, Spinal; Gene Expression Regulation; Kinetics; Mice; Muscimol; N-Methylaspartate; Neurons; RNA, Messenger; Second Messenger Systems; Spinal Cord; Substance P; Tetradecanoylphorbol Acetate; Tetrodotoxin; Time Factors; Transcription, Genetic; Vasoactive Intestinal Peptide | 1991 |
FK-506 and cyclosporin A: selective inhibition of calcium ionophore-induced polymorphonuclear leukocyte degranulation.
Topics: Anti-Bacterial Agents; Calcimycin; Cycloheximide; Cyclosporins; Dactinomycin; Humans; Immune Tolerance; Ionomycin; Lactoferrin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polyenes; Signal Transduction; Sirolimus; Tacrolimus; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C modulates immunoglobulin E-mediated activation of human mast cells from lung and skin. I. Pharmacologic inhibition.
Topics: Alkaloids; Antibodies, Anti-Idiotypic; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Dose-Response Relationship, Drug; Histamine Release; Humans; Immunoglobulin E; Lung; Mast Cells; Protein Kinase C; Signal Transduction; Skin; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
The antiviral effect of phorbol ester and calcium ionophore A23187 is not mediated by interferons.
Topics: Calcimycin; Cell Line; Culture Media; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Humans; Interferons; Tetradecanoylphorbol Acetate; Vesicular stomatitis Indiana virus; Viral Proteins; Virus Replication | 1991 |
A lavage method for dynamic intraarticular monitoring of animal joints in situ: quantification and release kinetics of histamine after selective synovial mast cell activation by diverse secretagogues.
Topics: Animals; Antigens; Calcimycin; Capillary Permeability; Histamine Release; Immune Sera; Immunization; Immunoglobulin E; Joints; Male; Mast Cells; Monitoring, Physiologic; p-Methoxy-N-methylphenethylamine; Rats; Rats, Inbred Strains; Synovial Membrane; Tetradecanoylphorbol Acetate; Therapeutic Irrigation | 1991 |
Role of pertussis toxin-sensitive G proteins in stimulus-dependent human eosinophil degranulation.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate Ribose; Antigens, Differentiation; Calcimycin; Cell Degranulation; Cholera Toxin; Cyclic AMP; Eosinophil-Derived Neurotoxin; Eosinophils; GTP-Binding Proteins; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neurotoxins; Pertussis Toxin; Phosphatidylinositols; Receptors, Fc; Receptors, Formyl Peptide; Receptors, IgG; Receptors, Immunologic; Ribonucleases; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1991 |
Regulation of peptide-YY synthesis and secretion in fetal rat intestinal cultures.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Cells, Cultured; Chromatography, High Pressure Liquid; Colforsin; Drug Synergism; Gastric Inhibitory Polypeptide; Gastrin-Releasing Peptide; Immunoenzyme Techniques; Intestinal Mucosa; Intestines; Peptide Biosynthesis; Peptide YY; Peptides; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Down-regulation by tumor necrosis factor-alpha of neutrophil cell surface expression of the sialophorin CD43 and the hyaluronate receptor CD44 through a proteolytic mechanism.
Topics: Antigens, CD; Calcimycin; Cell Adhesion Molecules; Down-Regulation; Flow Cytometry; Histocompatibility Antigens; Humans; L-Selectin; Leukocyte Common Antigens; Leukosialin; Macrophage-1 Antigen; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Precipitin Tests; Receptors, Lymphocyte Homing; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Effects of FK 506 and cyclosporine on T-cell tolerance: inhibition of a "protective" mechanism that regulates activation-induced apoptosis in developing thymocytes.
Topics: Animals; Calcimycin; Cell Death; Cells, Cultured; Cyclosporine; DNA; Immune Tolerance; Mice; Mice, Inbred C57BL; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate | 1991 |
Tributyltin stimulates reactive oxygen formation in toadfish macrophages.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Benzoates; Benzoic Acid; Calcimycin; Calcium; Calcium Channels; Fishes; Free Radical Scavengers; Free Radicals; Indomethacin; Luminescent Measurements; Macrophage Activation; Macrophages; Masoprocol; Oxygen; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Trialkyltin Compounds; Trifluoperazine; Verapamil | 1991 |
Triiodothyronine (T3) inhibition of growth hormone secretion by chicken pituitary cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Calcimycin; Cells, Cultured; Chickens; Colforsin; Diglycerides; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; In Vitro Techniques; Male; Pituitary Gland, Anterior; Radioimmunoassay; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triiodothyronine | 1991 |
Serum-free culture of fractionated bovine bronchial epithelial cells.
Topics: Animals; Bronchi; Calcimycin; Calcium; Cattle; Cell Division; Cell Separation; Centrifugation, Density Gradient; Culture Media, Serum-Free; Culture Techniques; Epidermal Growth Factor; Epithelial Cells; Epithelium; Kinetics; Mitotic Index; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1992 |
The effect of interleukin-4 on the macrophage respiratory burst is species dependent.
Topics: Animals; Calcimycin; Cells, Cultured; Cytokines; Humans; Interferon-gamma; Interleukin-4; Kinetics; Lipopolysaccharides; Macrophages; Mice; N-Formylmethionine Leucyl-Phenylalanine; Oxygen Consumption; Recombinant Proteins; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Phagocytosis of Giardia lamblia trophozoites by cytokine-activated macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow Cells; Calcimycin; Cells, Cultured; Cytokines; Giardia lamblia; In Vitro Techniques; Interferon-gamma; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Phagocytosis; Piperazines; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1992 |
Ethanol is a potent stimulator of phosphatidylcholine breakdown in cultured rat hepatocytes.
Topics: Adenosine Triphosphate; Alcohols; Animals; Calcimycin; Cells, Cultured; Choline; Ethanol; Inositol Phosphates; Liver; Norepinephrine; Phosphatidylcholines; Phospholipases; Phosphorylcholine; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1992 |
EGF-induced jun B-expression in transfected P19 embryonal carcinoma cells expressing EGF-receptors is dependent on Jun D.
Topics: Blotting, Northern; Calcimycin; Chloramphenicol O-Acetyltransferase; Drug Synergism; Embryonal Carcinoma Stem Cells; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation; Genes, jun; Neoplastic Stem Cells; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Repetitive Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1992 |
JB6 murine epidermal cell lines sensitive and resistant to 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced transformation exhibit differential arachidonic acid metabolism in response to TPA and the calcium ionophore A23187.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcimycin; Cell Line; Cell Line, Transformed; Chromatography, High Pressure Liquid; Dinoprostone; Drug Resistance; Epoprostenol; Mice; Mice, Inbred BALB C; Radioimmunoassay; Skin; Tetradecanoylphorbol Acetate | 1992 |
Differentiation-associated expression of prostaglandin H and thromboxane A synthases in monocytoid leukemia cell lines.
Topics: Arachidonic Acid; Calcimycin; Cell Differentiation; Granulocytes; Humans; Leukemia; Lipoxygenase; Monocytes; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Thromboxane-A Synthase; Tretinoin; Tumor Cells, Cultured | 1991 |
Inhibition of PGE2 production in macrophages from vitamin E-treated rats.
Topics: Animals; Arachidonic Acid; Calcimycin; Cyclooxygenase Inhibitors; Dinoprostone; Macrophages; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vitamin E | 1991 |
Implications of prostaglandin E2 synthesis and phospholipase C activation in potentiation of T-cell proliferation by LF 1695.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Concanavalin A; Dinoprostone; Inositol Phosphates; Lymphocyte Activation; Mice; Piperidines; Signal Transduction; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1991 |
Phorbol myristate acetate and calcium ionophore A23187 modulate the accessory cell function of mouse dendritic cells.
Topics: Animals; Calcimycin; Cell Division; Dendritic Cells; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mitosis; Tetradecanoylphorbol Acetate | 1991 |
Control of nucleoside transport in neural cells. Effect of protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adrenal Medulla; Animals; Biological Transport; Calcimycin; Caprylates; Cells, Cultured; Diglycerides; Dinucleoside Phosphates; Enzyme Activation; Ethers, Cyclic; Isoquinolines; Kinetics; Okadaic Acid; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Triglycerides | 1991 |
Effect of tumour-promoting phorbol ester on calcium homeostasis in human platelets.
Topics: Adenosine Triphosphate; Blood Platelets; Calcimycin; Calcium; Homeostasis; Humans; Platelet Activation; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Postnatal development of murine spleen cell proliferative responses induced by interleukin 2 or phorbol ester and calcium ionophore A23187.
Topics: Aging; Animals; Calcimycin; Interleukin-2; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred A; Mice, Inbred AKR; Mice, Inbred C3H; Spleen; Tetradecanoylphorbol Acetate | 1991 |
Alterations of T-cell functions during Friend leukemia complex infection: defective signal transduction?
Topics: Animals; Calcimycin; Concanavalin A; Filtration; Fluorescent Antibody Technique; Friend murine leukemia virus; Immunophenotyping; Interferon-gamma; Interleukin-2; Leukemia, Experimental; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Selective incorporation of 15-HETE in phosphatidylinositol: agonist-induced deacylation and transformation of stored HETEs by human neutrophils.
Topics: Acylation; Calcimycin; Cell Aggregation; Esterification; Humans; Hydroxyeicosatetraenoic Acids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols; Tetradecanoylphorbol Acetate | 1991 |
Prostacyclin secretion and specific intracellular protein phosphorylation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bradykinin; Calcimycin; Cattle; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Heat-Shock Proteins; Hot Temperature; Isoquinolines; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Secretory Rate; Staurosporine; Tamoxifen; Tetradecanoylphorbol Acetate | 1991 |
Eicosanoid synthesis in murine macrophages can be shifted from prostaglandins to leukotrienes but not vice versa by specific inhibitors of cyclooxygenase or 5'-lipoxygenase activity.
Topics: Animals; Calcimycin; Calcium; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Indoles; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Macrophages; Mice; Mice, Inbred DBA; Prostaglandins; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Translocation of CD45RA in neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Differentiation; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Cell Membrane; Flow Cytometry; Gene Expression Regulation; Histocompatibility Antigens; Humans; Isoantigens; Isoquinolines; Leukocyte Common Antigens; Neutrophils; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Up-Regulation | 1991 |
Effect of interleukins and anti-CD3 monoclonal antibody on the proliferation of thymocytes from irradiated mice.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Cell Division; Female; Interleukins; Male; Mice; Mice, Inbred C3H; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Regulation of thymocyte proliferation by alpha beta TcR+ CD3+ CD4- CD8- cloned natural suppressor (NS) cells.
Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; CD4 Antigens; CD8 Antigens; Clone Cells; DNA; Female; Interleukin-2; Interleukin-4; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Phytohemagglutinins; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocytes; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 1991 |
Endocytosis of the TCR/CD3 complex and the class-I major histocompatibility complex in a human T cell line.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcimycin; Calcium; CD3 Complex; Cell Compartmentation; Cell Line; Cell Membrane; Cytoplasmic Granules; Endocytosis; Fluorescent Antibody Technique; Histocompatibility Antigens Class I; Humans; In Vitro Techniques; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
[Effects of gossypol (+,-,+) on phorbol ester and A23187-stimulated prostaglandin synthesis by macrophages].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcimycin; Dinoprost; Gossypol; Macrophages; Mice; Peritoneal Cavity; Stereoisomerism; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1991 |
Induction of long-term but reversible unresponsiveness after activation of murine T cell hybridomas.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Cell Membrane; Hybridomas; Immune Tolerance; Interleukin-2; Lymphocyte Activation; Mice; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Analysis of phenotypic and functional changes during ganglioside-induced inhibition of human T cell proliferation.
Topics: Antigens, CD; B-Lymphocytes; Blotting, Northern; Calcimycin; Cells, Cultured; Gangliosides; Histocompatibility Antigens Class I; Humans; Immunophenotyping; In Vitro Techniques; Interleukin-1; Interleukin-2; Lymphocyte Activation; Phytohemagglutinins; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Transferrin; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Bispecific antibody-directed antitumor activity of human CD4+ helper/killer T cells induced by anti-CD3 monoclonal antibody plus interleukin 2.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; CD4 Antigens; Cell Line; Cells, Cultured; Cytotoxicity, Immunologic; DNA Replication; Glioma; Humans; Interleukin-2; Killer Cells, Natural; Kinetics; Lymphocyte Activation; Receptors, Antigen, T-Cell; Recombinant Proteins; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Thymidine | 1991 |
Modulation of natural and interleukin-2-induced tumour-cytolytic activities by the members of a protein family related to beta-thromboglobulin.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Arthropod Proteins; beta-Thromboglobulin; Burkitt Lymphoma; Calcimycin; Cells, Cultured; Cytotoxicity, Immunologic; Drug Synergism; Enzyme Precursors; Humans; Immunity, Cellular; Immunotherapy; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocytes; Molecular Sequence Data; Serine Endopeptidases; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1991 |
IFN-gamma induces the expression of the genes for MHC class II I-A beta and tumor necrosis factor through a protein kinase C-independent pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bone Marrow Cells; Calcimycin; Calmodulin; Gene Expression Regulation; Histocompatibility Antigens Class II; Interferon-gamma; Ionomycin; Isoquinolines; Macrophages; Major Histocompatibility Complex; Mice; Mice, Inbred DBA; Piperazines; Protein Kinase C; RNA, Messenger; Sphingosine; Sulfonamides; Tetradecanoylphorbol Acetate; Trifluoperazine; Tumor Necrosis Factor-alpha | 1991 |
The expression of IL-2R alpha-chain is enhanced by activation of adenylate cyclase in large granular lymphocytes and natural killer cells.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Cell Division; Cell Line; Colforsin; Cyclic AMP; Gene Expression; Humans; In Vitro Techniques; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Macromolecular Substances; Mice; Mice, Inbred C57BL; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Norepinephrine stimulates potassium efflux from pinealocytes: evidence for involvement of biochemical "AND" gate operated by calcium and adenosine 3',5'-monophosphate.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Female; Kinetics; Male; Models, Biological; Norepinephrine; Ovariectomy; Pineal Gland; Potassium; Potassium Channels; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Rubidium; Sodium; Tetradecanoylphorbol Acetate | 1991 |
Second messenger pathways in lymphocyte binding and penetration through graft vascular endothelium.
Topics: Animals; Bucladesine; Calcimycin; Cell Communication; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Lymphocytes; Platelet Activating Factor; Rats; Rats, Inbred Strains; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes.
Topics: Binding Sites; Calcimycin; Diglycerides; Enzyme Activation; Humans; Kinetics; Leukotriene B4; Monocytes; Opsonin Proteins; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
High molecular weight kininogen inhibits thrombin-induced platelet aggregation and cleavage of aggregin by inhibiting binding of thrombin to platelets.
Topics: Adenosine Triphosphate; Blood Platelets; Calcimycin; Calcium; Collagen; Cyclic AMP; Humans; Kininogens; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Binding; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Non-mitogenic T cell activation signals are sufficient for induction of human immunodeficiency virus transcription.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Calcium; CD28 Antigens; CD3 Complex; Enhancer Elements, Genetic; Gene Expression Regulation, Viral; HIV Long Terminal Repeat; HIV-1; Humans; In Vitro Techniques; Lymphocyte Activation; Receptors, Antigen, T-Cell; Receptors, Immunologic; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Stability of the acrosome of the brush-tailed possum (Trichosurus vulpecula) and tammar wallaby (Macropus eugenii) in vitro and after exposure to conditions and agents known to cause capacitation or acrosome reaction of eutherian spermatozoa.
Topics: Acrosome; Animals; Bucladesine; Calcimycin; Cell Membrane; Cells, Cultured; Dibutyryl Cyclic GMP; Diglycerides; Lysophosphatidylcholines; Macropodidae; Male; Marsupialia; Microscopy, Electron; Sperm Capacitation; Spermatozoa; Tetradecanoylphorbol Acetate; Trypsin | 1991 |
A novel mechanism of glucocorticosteroid (GC) action in suppression of phospholipase A2 (PLA2) activity stimulated by Ca2+ ionophore A23187: induction of protein phosphatases.
Topics: Animals; Annexins; Calcimycin; Calcium-Binding Proteins; Dexamethasone; Enzyme Activation; Enzyme Induction; Mice; Models, Biological; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Phosphoric Diester Hydrolases; Phosphorylation; Protein Processing, Post-Translational; Signal Transduction; Tetradecanoylphorbol Acetate | 1991 |
Phosphatidylinositol-specific phospholipase C induces biosynthesis of acetylcholinesterase via diacylglycerol in Schistosoma mansoni.
Topics: Acetylcholinesterase; Animals; Bacillus thuringiensis; Biomphalaria; Calcimycin; Cycloheximide; Diglycerides; Female; Kinetics; Methionine; Mice; Mice, Inbred Strains; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Polymyxin B; Schistosoma mansoni; Staphylococcus aureus; Structure-Activity Relationship; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate | 1991 |
Transfected D2 dopamine receptors mediate the potentiation of arachidonic acid release in Chinese hamster ovary cells.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Apomorphine; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine; Drug Synergism; Ergolines; Haloperidol; In Vitro Techniques; Melitten; Pertussis Toxin; Protein Kinase C; Quinpirole; Receptors, Dopamine; Sulpiride; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella | 1991 |
Regulation of ANF receptor internalization: involvement of extracellular calcium.
Topics: Adrenal Gland Neoplasms; Animals; Atrial Natriuretic Factor; Calcimycin; Calcium; Cell Membrane; Kinetics; Membrane Proteins; Molecular Weight; Pheochromocytoma; Phosphoproteins; Phosphorylation; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1991 |
Genistein, a selective protein tyrosine kinase inhibitor, inhibits interleukin-2 and leukotriene B4 production from human mononuclear cells.
Topics: Calcimycin; Cells, Cultured; Genistein; Humans; Interleukin-2; Isoflavones; Leukocytes, Mononuclear; Leukotriene B4; Lymphocyte Activation; Phytohemagglutinins; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate | 1991 |
[The activation of the early chemiluminescent response of human neutrophils by joint treatment with tumor necrosis factor (TNF-alpha) and the calcium ionophore A-23187].
Topics: Acridines; Calcimycin; Cells, Cultured; Humans; Luminescent Measurements; Luminol; Neutrophils; Oxygen; Precancerous Conditions; Recombinant Proteins; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1991 |
Time-dependent biphasic regulation of Na+/K+/Cl- cotransport in rat glomerular mesangial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Biological Transport; Bumetanide; Calcimycin; Chlorides; Colforsin; Glomerular Mesangium; In Vitro Techniques; Potassium; Rats; Sodium; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1991 |
The Ca2+ second messenger system and interleukin-1-alpha modulation of hepatic gene transcription and mitochondrial fat oxidation.
Topics: Animals; Calcimycin; Calcium; Carnitine O-Palmitoyltransferase; Gene Expression Regulation, Enzymologic; Interleukin-1; Lipid Metabolism; Liver; Male; Oxidation-Reduction; Protein Biosynthesis; Protein Kinase C; Rats; Rats, Inbred Strains; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1991 |
Activation of membrane protein kinase C by glucagon and Ca(2+)-mobilizing hormones in cultured rat hepatocytes. Role of phosphatidylinositol and phosphatidylcholine hydrolysis.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Calcimycin; Cell Membrane; Cells, Cultured; Enzyme Activation; Glucagon; Hydrolysis; Inositol Phosphates; Kinetics; Liver; Myristic Acid; Myristic Acids; Norepinephrine; Phosphatidylcholines; Phosphatidylinositols; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1991 |
Bronchial epithelial cells release monocyte chemotactic activity in response to smoke and endotoxin.
Topics: Animals; Bronchi; Calcimycin; Cattle; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Chromatography, Gel; Chromatography, High Pressure Liquid; Cycloheximide; Diethylcarbamazine; Dose-Response Relationship, Drug; Endotoxins; Hydrocortisone; In Vitro Techniques; Indomethacin; Masoprocol; Monocytes; Smoke; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
[The role of signal transduction systems in the regulation of the production and secretion of hCG (alpha, beta) by cultured human choriocarcinoma cells (BeWo)].
Topics: Calcimycin; Cholera Toxin; Choriocarcinoma; Chorionic Gonadotropin; Humans; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Synthesis of intracellular histamine in platelets is associated with activation of protein kinase C, but not with mobilization of Ca2+.
Topics: Adenosine Diphosphate; Alkaloids; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Collagen; Cyclooxygenase Inhibitors; Enzyme Activation; Histamine; Humans; Phosphoproteins; Phosphorylation; Platelet Aggregation; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Potentiation of arachidonic acid release by phorbol myristate acetate in platelets is not due to inhibition of arachidonic acid uptake or incorporation into phospholipids.
Topics: 8,11,14-Eicosatrienoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Humans; In Vitro Techniques; Phospholipids; Tetradecanoylphorbol Acetate | 1991 |
Calcitriol-mediated modulation of urokinase-type plasminogen activator and plasminogen activator inhibitor-2.
Topics: Blotting, Northern; Calcimycin; Calcitriol; Calcium; Humans; Plasminogen Activators; Plasminogen Inactivators; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator | 1991 |
Investigation of the mechanism of biosynthesis of 8-hydroxyeicosatetraenoic acid in mouse skin.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Female; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Mass Spectrometry; Mice; Mice, Inbred C57BL; Skin; Stereoisomerism; Tetradecanoylphorbol Acetate | 1991 |
Endogenous activation of prostaglandin synthesis in rabbit colonic explants cultured in vitro.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Fractionation; Cell Membrane; Cells, Cultured; Colon; Cycloheximide; Cytochalasin B; Dinoprostone; In Vitro Techniques; Male; Prostaglandin-Endoperoxide Synthases; Rabbits; Tetradecanoylphorbol Acetate | 1991 |
Selective deficiency of interferon-gamma production in the hyper-IgE syndrome. Relationship to in vitro IgE synthesis.
Topics: Adolescent; Adult; Calcimycin; Child; Child, Preschool; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypergammaglobulinemia; Hypersensitivity, Immediate; Immunoglobulin E; Interferon-gamma; Interleukin-4; Lymphocyte Activation; Male; Middle Aged; Mitogens; Recombinant Proteins; Syndrome; Tetradecanoylphorbol Acetate | 1991 |
Inhibition of translational initiation by metalloendoprotease antagonists. Evidence for involvement of sequestered Ca2+ stores.
Topics: Amino Acid Sequence; Animals; Calcimycin; Calcium; Carrier Proteins; Cell Line; Cycloheximide; Dactinomycin; Dipeptides; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Immunoglobulin Heavy Chains; Inositol Phosphates; Kinetics; Leucine; Leupeptins; Metalloendopeptidases; Molecular Chaperones; Molecular Sequence Data; Oligopeptides; Peptide Chain Initiation, Translational; Phorbol 12,13-Dibutyrate; RNA, Messenger; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1991 |
c-fos mRNA expression in macrophages is downregulated by interferon-gamma at the posttranscriptional level.
Topics: Animals; Calcimycin; Cells, Cultured; Kinetics; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
c-fos gene transcription in murine macrophages is modulated by a calcium-dependent block to elongation in intron 1.
Topics: Animals; Calcimycin; Calcium; Cell Nucleus; Cells, Cultured; Gene Expression Regulation; Introns; Macrophages; Mice; Mice, Inbred CBA; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
C20 polyunsaturated fatty acids and phorbol myristate acetate enhance agonist-stimulated synthesis of 1-radyl-2-acetyl-sn-glycero-3-phosphocholine in vascular endothelial cells.
Topics: Acetates; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cattle; Endothelium, Vascular; Fatty Acids, Unsaturated; Kinetics; Phosphatidylcholines; Sphingosine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tritium | 1991 |
T cell receptor activation induces rapid phosphorylation of prosolin, which mediates down-regulation of DNA synthesis in proliferating peripheral lymphocytes.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD4 Antigens; CD8 Antigens; DNA; Down-Regulation; Humans; Lymphocyte Activation; Lymphocytes; Phosphoproteins; Phosphorylation; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate | 1991 |
Comparison of arachidonate metabolism by alveolar macrophages from bighorn and domestic sheep.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Disease Susceptibility; Female; Genetic Predisposition to Disease; Lipoxygenase; Macrophages; Male; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Respiratory Tract Infections; Sheep; Species Specificity; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Phorbol ester plus calcium ionophore induces release of arachidonic acid from membrane phospholipids of a human B cell line.
Topics: Arachidonic Acid; Arachidonic Acids; B-Lymphocytes; Calcimycin; Cell Line; Humans; Hydroxyeicosatetraenoic Acids; Membrane Lipids; Phospholipids; Protein Kinase C; Stearic Acids; Tetradecanoylphorbol Acetate | 1991 |
Inhibition of growth hormone secretion by activin A in human growth hormone-secreting tumour cells.
Topics: Activins; Adult; Calcimycin; Calcium; Cytoplasm; Dose-Response Relationship, Drug; Female; Growth Hormone; Humans; Inhibins; Male; Middle Aged; Pituitary Neoplasms; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1991 |
Release of arachidonic acid by complement C5b-9 complex in glomerular epithelial cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Complement Membrane Attack Complex; Cyclohexanones; Diglycerides; Edetic Acid; Egtazic Acid; Epithelium; Fatty Acids, Nonesterified; Kidney Glomerulus; Kinetics; Lipase; Lipoprotein Lipase; Phospholipases A; Phospholipases A2; Phospholipids; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1991 |
Pertussis and cholera toxins inhibit prostaglandin synthesis in rat astrocyte cultures at distinct metabolic steps.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Arachidonic Acids; Astrocytes; Calcimycin; Cells, Cultured; Cholera Toxin; GTP-Binding Proteins; Pertussis Toxin; Phospholipases A; Phospholipases A2; Prostaglandin D2; Prostaglandins; Radioimmunoassay; Rats; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Toxins; Calcimycin; Camptothecin; Cell Survival; Cells, Cultured; Cycloheximide; Dactinomycin; Endotoxins; Enterotoxins; Enzyme Activation; Isoquinolines; Macrophages; Male; Piperazines; Protein Biosynthesis; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1991 |
Inhibition of Ehrlichia risticii infection in murine peritoneal macrophages by gamma interferon, a calcium ionophore, and concanavalin A.
Topics: Animals; Calcimycin; Cells, Cultured; Concanavalin A; Ehrlichia; Female; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Peritoneal Cavity; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thioglycolates | 1991 |
Cellular mechanism of synergistic stimulation of PGE2 production by phorbol diester and Ca2+ ionophore A23187 in cultured Madin-Darby canine kidney cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Dinoprostone; Dogs; Drug Synergism; Kidney; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Inhibition of phorbol ester-induced cell activation in microgravity.
Topics: Calcimycin; Interleukin-1; Interleukin-2; Lymphocyte Activation; Monocytes; Protein Kinase C; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Weightlessness | 1991 |
Studies on the mechanism of Salmonella typhimurium enterotoxin-induced diarrhoea.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Calcimycin; Calcium; Chlorides; Diarrhea; Enterotoxins; Indomethacin; Intestinal Mucosa; Intestine, Small; Isoquinolines; Male; Piperazines; Prostaglandins; Protein Kinase C; Rats; Rats, Inbred Strains; Salmonella typhimurium; Sodium; Tetradecanoylphorbol Acetate; Verapamil; Water-Electrolyte Balance | 1991 |
Protein kinase C regulates proliferation of mast cells and the expression of the mRNAs of fos and jun proto-oncogenes during activation by IgE-Ag or calcium ionophore A23187.
Topics: Animals; Calcimycin; Cell Division; Cell Line, Transformed; Dinitrophenols; Gene Expression Regulation; Genes, fos; Genes, jun; Immunoglobulin E; Leukemia, Basophilic, Acute; Liver; Mast Cells; Mice; Protein Kinase C; Rats; RNA, Messenger; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Correlation between secretion pattern and metastatic potential from drug-treated 3LL tumor cell line.
Topics: Animals; Calcimycin; Female; Indomethacin; Lung Neoplasms; Mice; Mice, Inbred BALB C; Molecular Weight; Neoplasm Metastasis; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Characterization of the mouse granulocyte-macrophage colony-stimulating factor (GM-CSF) gene promoter: nuclear factors that interact with an element shared by three lymphokine genes--those for GM-CSF, interleukin-4 (IL-4), and IL-5.
Topics: Animals; Base Sequence; Binding, Competitive; Calcimycin; DNA; DNA-Binding Proteins; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-4; Interleukin-5; Mice; Molecular Sequence Data; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1991 |
The lectin wheat germ agglutinin stimulates a protein-tyrosine kinase activity of p72syk in porcine splenocytes.
Topics: Acetylglucosamine; Animals; Calcimycin; Lymphocytes; Molecular Sequence Data; Phosphorylation; Protein-Tyrosine Kinases; Spleen; Swine; Tetradecanoylphorbol Acetate; Wheat Germ Agglutinins | 1991 |
Expression of Hanganutziu-Deicher antigen in activated human T lymphocytes.
Topics: Antigens, Heterophile; Blotting, Western; Calcimycin; Cells, Cultured; Humans; Interleukin-2; Lymphocyte Activation; Molecular Weight; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
The early induction of the actin-sequestering peptide thymosin beta 4 in thymocytes depends on the proliferative stimulus.
Topics: Animals; Calcimycin; Cell Division; Concanavalin A; Female; Gene Expression; Microfilament Proteins; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Receptors, Antigen, T-Cell; Receptors, Concanavalin A; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thymosin; Thymus Gland | 1991 |
Ionizing radiation at low doses induces inflammatory reactions in human blood.
Topics: Arachidonic Acid; Blood; Blood Cells; Calcimycin; Dose-Response Relationship, Radiation; Escherichia coli; Gamma Rays; Humans; Inflammation; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Radiation Dosage; Respiratory Burst; Saponins; Tetradecanoylphorbol Acetate | 1991 |
Early changes in phosphoprotein patterns of Friend erythroleukaemia cells induced by dimethylsulphoxide or phorbol esters.
Topics: Animals; Calcimycin; Cell Differentiation; Cyclic AMP; Cyclic GMP; Dimethyl Sulfoxide; Friend murine leukemia virus; Kinetics; Leukemia, Erythroblastic, Acute; Mice; Phosphoproteins; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Activation of cyclic AMP phosphodiesterase by phorbol and protein kinase C pathway: differences in normal and diabetic tissue.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Calcimycin; Diabetes Mellitus, Experimental; Diglycerides; Enzyme Activation; Insulin; Male; Nifedipine; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Tetradecanoylphorbol Acetate | 1990 |
Further evidence for abnormal protein kinase C regulation of macromolecule secretion in fibroblasts from cystic fibrosis patients.
Topics: Binding Sites; Bucladesine; Calcimycin; Cells, Cultured; Colforsin; Cystic Fibrosis; Dose-Response Relationship, Drug; Fibroblasts; Glycoconjugates; Humans; Isoproterenol; Phorbol 12,13-Dibutyrate; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate | 1990 |
Inflammation of guinea pig dermis. Effects of leukotriene B4 receptor antagonist, SC-41930.
Topics: Administration, Cutaneous; Animals; Benzopyrans; Calcimycin; Disease Models, Animal; Guinea Pigs; Inflammation; Male; Psoriasis; Receptors, Immunologic; Receptors, Leukotriene B4; Skin; Tetradecanoylphorbol Acetate | 1990 |
Role of phosphatidylinositol-anchored proteins in T cell activation.
Topics: Animals; Antigen-Presenting Cells; Antigens, Ly; Antigens, Surface; Calcimycin; Concanavalin A; Flow Cytometry; Gene Expression Regulation; Glycosylphosphatidylinositols; Lymphocyte Activation; Mice; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Polysaccharides; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thy-1 Antigens | 1990 |
Effect of sulphasalazine and sulphapyridine on neutrophil superoxide production: role of cytosolic free calcium.
Topics: Calcimycin; Calcium; Cells, Cultured; Cytosol; Humans; Neutrophils; Sulfanilamides; Sulfapyridine; Sulfasalazine; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Gastrin secretion from human antral G cells in culture.
Topics: Bombesin; Calcimycin; Cells, Cultured; Chromaffin System; Colforsin; Enterochromaffin Cells; Gastrins; Humans; Pyloric Antrum; Receptors, Gastrointestinal Hormone; Somatostatin; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1990 |
CD4+CD8+ thymocytes are susceptible to DNA fragmentation induced by phorbol ester, calcium ionophore and anti-CD3 antibody.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; CD4-Positive T-Lymphocytes; DNA; Mice; Mice, Inbred C57BL; Receptors, Antigen, T-Cell; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 1990 |
Release of somatostatin immunoreactivity from human antral D cells in culture.
Topics: Adult; Bombesin; Calcimycin; Cells, Cultured; Colforsin; Female; Gastric Mucosa; Gastrins; Humans; Male; Pyloric Antrum; Radioimmunoassay; Reference Values; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate | 1990 |
Proliferation, interleukin-2 production and receptor expression in peripheral blood mononuclear cells from colorectal cancer patients.
Topics: Aged; Calcimycin; Colorectal Neoplasms; Female; Humans; Interleukin-2; Killer Cells, Natural; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate | 1990 |
Basis for defective proliferation of peripheral blood T cells to anti-CD2 antibodies in primary Sjögren's syndrome.
Topics: Adrenal Cortex Hormones; Adult; Antibodies, Monoclonal; Antigen-Presenting Cells; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD2 Antigens; Female; Gene Expression; Humans; Interleukin-1; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; Receptors, Immunologic; Receptors, Interleukin-2; Sjogren's Syndrome; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Induction of DNA fragmentation in chronic B-lymphocytic leukemia cells.
Topics: Antibodies, Monoclonal; Calcimycin; Calcium; Cell Survival; DNA, Neoplasm; Glucocorticoids; Humans; Immunoglobulin M; Leukemia, Lymphocytic, Chronic, B-Cell; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Effect of cyclosporine A (CyA) on secreted T proteins from T lymphocytes stimulated by PMA/calcium ionophore.
Topics: Calcimycin; Cell Line; Cells, Cultured; Cyclosporins; Electrophoresis, Gel, Two-Dimensional; Graft Rejection; Humans; Kidney Transplantation; Lymphocyte Activation; Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1991 |
Macrophage colony-stimulating factor (CSF-1) gene expression in human T-lymphocyte clones.
Topics: Antigens; Calcimycin; Clone Cells; Gene Expression; Graft Rejection; Graft vs Host Disease; Humans; Isoantigens; Macrophage Colony-Stimulating Factor; Nucleic Acid Hybridization; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Effects of zymosan-activated human granulocytes on isolated human airways.
Topics: Adult; Aged; Aged, 80 and over; Autonomic Fibers, Postganglionic; Bronchoconstriction; Calcimycin; Concanavalin A; Electric Stimulation; Female; Granulocytes; Humans; Hypersensitivity, Immediate; In Vitro Techniques; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Arachidonic acid release by basophilic leukemia cells and macrophages stimulated by Ca2+ ionophores, antigen and diacylglycerol: essential role for protein kinase C and prevention by glucocorticosteroids.
Topics: Alkaloids; Animals; Antigens; Arachidonic Acids; Calcimycin; Carbazoles; Cell Line; Cell Membrane; Cells, Cultured; Dexamethasone; Immunoglobulin E; Indole Alkaloids; Ionomycin; Kinetics; Leukemia, Basophilic, Acute; Leukemia, Experimental; Macrophages; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Serum Albumin, Bovine; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Neutrophil erythrotoxicity induced by phorbol myristate acetate: mechanisms involved in neutrophil activation.
Topics: Antigen-Antibody Complex; Calcimycin; Catalase; Cell Adhesion; Cell Survival; Chemotaxis; Dose-Response Relationship, Drug; Erythrocytes; Humans; Immunity, Cellular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Platelet Activating Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Multiple signals activate cleavage of the membrane transforming growth factor-alpha precursor.
Topics: Animals; Calcimycin; Calcium; Cell Line; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Kinetics; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1991 |
Post-transcriptional regulation of cytoskeletal actin and T lymphocyte receptor beta chain mRNA by phorbol ester.
Topics: Actins; Calcimycin; Cyclosporins; Cytoplasm; Dactinomycin; Gene Expression Regulation; Humans; Protein Kinase C; Receptors, Antigen, T-Cell; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Control of steroidogenesis by the calcium messenger system in human adrenocortical cells.
Topics: Adrenal Cortex; Calcimycin; Calcium; Humans; In Vitro Techniques; Protein Kinase C; Second Messenger Systems; Steroids; Tetradecanoylphorbol Acetate; Verapamil | 1991 |
Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetylcholine; Animals; Aorta; Calcimycin; Endothelium, Vascular; Enzyme Activation; Glucose; In Vitro Techniques; Isoquinolines; Piperazines; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Vasodilation | 1991 |
High-affinity interleukin 2 receptors on B cell chronic lymphocytic leukemia cells are induced by phorbol myristate acetate but not by calcium ionophore.
Topics: Antigens, Surface; B-Lymphocytes; Binding Sites; Calcimycin; Calcium; Electrophoresis, Polyacrylamide Gel; Humans; Immunophenotyping; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Protein Kinase C; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate | 1991 |
Effects of polyene antibiotics on the activation of human polymorphonuclear leukocytes.
Topics: Amphotericin B; Calcimycin; Dose-Response Relationship, Drug; Free Radicals; Humans; Kinetics; Latex; Luminescent Measurements; Lymphocyte Activation; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Potassium; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Zona pellucida-mediated acrosomal exocytosis in mouse spermatozoa: characterization of an intermediate stage prior to the completion of the acrosome reaction.
Topics: Acrosome; Animals; Calcimycin; Cell Membrane Permeability; Chlortetracycline; Exocytosis; Female; Fluorescent Antibody Technique; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Microscopy, Electron; Nigericin; Rats; Sperm Capacitation; Sperm-Ovum Interactions; Tetradecanoylphorbol Acetate; Time Factors; Zona Pellucida | 1991 |
Antigen-induced biphasic diacylglycerol formation in RBL-2H3 cells: the late sustained phase due to phosphatidylcholine hydrolysis is dependent on protein kinase C.
Topics: Animals; Antigens; Calcimycin; Cell Line; Choline; Diglycerides; Hydrolysis; Kinetics; Leukemia, Basophilic, Acute; Myristic Acid; Myristic Acids; Phosphatidylcholines; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1991 |
Definition of a GC-rich motif as regulatory sequence of the human IL-3 gene: coordinate regulation of the IL-3 gene by CLE2/GC box of the GM-CSF gene in T cell activation.
Topics: Base Composition; Base Sequence; Calcimycin; Enhancer Elements, Genetic; Gene Expression Regulation; Gene Products, tax; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Lymphocyte Activation; Molecular Sequence Data; Promoter Regions, Genetic; Sequence Homology, Nucleic Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1991 |
Down-regulation of messenger ribonucleic acid and protein levels for estrogen receptors by phorbol ester and calcium in MCF-7 cells.
Topics: Breast Neoplasms; Calcimycin; Calcium; Down-Regulation; Estradiol; Humans; Kinetics; Receptors, Estrogen; Receptors, Progesterone; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Effects of gossypol on phorbol ester-calcimycin-induced prostaglandin synthesis by macrophages.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Calcimycin; Dinoprost; Female; Gossypol; Macrophages; Mice; Peritoneal Cavity; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1991 |
ROS ingestion by RPE cells is turned off by increased protein kinase C activity and by increased calcium.
Topics: Animals; Calcimycin; Calcium; Culture Techniques; Phagocytosis; Phorbol Esters; Pigment Epithelium of Eye; Protein Kinase C; Rats; Rats, Inbred Strains; Rod Cell Outer Segment; Tetradecanoylphorbol Acetate | 1991 |
Differential modulation of the in vitro lymphocyte activation pathways by soluble and solubilized placental substances.
Topics: Adjuvants, Immunologic; Animals; Calcimycin; Cell Division; Concanavalin A; Detergents; Female; Glucosides; Isoantigens; Lipopolysaccharides; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Placenta; Pregnancy; Solubility; Tetradecanoylphorbol Acetate; Tissue Extracts | 1990 |
Inducible and non-inducible factors co-operatively activate the GM-CSF promoter by interacting with two adjacent DNA motifs.
Topics: Animals; Base Sequence; Binding Sites; Calcimycin; DNA; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Mice; Molecular Sequence Data; Promoter Regions, Genetic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation | 1990 |
Detection of function-associated molecules on rat leukemic NK cells: activation by monoclonal antibody or phorbol ester.
Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Calcimycin; Cell Line; Cytotoxicity, Immunologic; Killer Cells, Natural; Kinetics; Leukemia, Experimental; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Protein kinase C acts downstream of calcium at entry into the first mitotic interphase of Xenopus laevis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Egtazic Acid; Exocytosis; Interphase; Isoquinolines; Oocytes; Piperazines; Protein Kinase C; Signal Transduction; Sphingosine; Sulfonamides; Tetradecanoylphorbol Acetate; Xenopus laevis | 1990 |
Primary stimuli of icosanoid release inhibit arachidonoyl-CoA synthetase and lysophospholipid acyltransferase. Mechanism of action of hydrogen peroxide and methyl mercury in platelets.
Topics: Acyltransferases; Blood Platelets; Calcimycin; Calcium; Coenzyme A Ligases; Diglycerides; Eicosanoids; Glutathione; Humans; Hydrogen Peroxide; Kinetics; Lysophospholipase; Methylmercury Compounds; Microsomes; Multienzyme Complexes; Phospholipases; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Increase in histone poly (ADP-ribosylation) in mitogen-activated lymphoid cells.
Topics: Calcimycin; Cell Line; Histones; Humans; Lymphocyte Activation; NAD; Nucleoside Diphosphate Sugars; Phytohemagglutinins; Poly Adenosine Diphosphate Ribose; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Cluster formation of canine dendritic cells and lymphocytes is calcium dependent and not inhibited by cyclosporine.
Topics: Animals; Calcimycin; Calcium; Concanavalin A; Cyclosporins; Dendritic Cells; Dogs; Lymphocyte Activation; Tetradecanoylphorbol Acetate; Verapamil | 1990 |
Activation of human neutrophil phospholipase D by three separable mechanisms.
Topics: Androstadienes; Calcimycin; Calcium; Cell Adhesion; Cell Aggregation; Egtazic Acid; Enzyme Activation; Glycerophospholipids; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phospholipase D; Phospholipases; Protein Kinase C; Tetradecanoylphorbol Acetate; Wortmannin | 1990 |
Regulation of interleukin 3 mRNA expression in mast cells occurs at the posttranscriptional level and is mediated by calcium ions.
Topics: Animals; Calcimycin; Calcium; Cell Line; Cell Nucleus; Cells, Cultured; Colony-Stimulating Factors; Cycloheximide; Dactinomycin; Gene Expression Regulation; Genes; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Interleukin-3; Mast Cells; Mice; Protein Kinase C; RNA Processing, Post-Transcriptional; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Activation signals in human lymphocytes: interleukin 2 synthesis and expression of high affinity interleukin 2 receptors require differential signalling for the activation of protein kinase C.
Topics: Biological Transport; Calcimycin; Diglycerides; Enzyme Activation; Humans; Interleukin-2; Lymphocyte Activation; Protein Kinase C; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Pertussis toxin and H-7 distinguish mechanisms involved in eicosanoid release from lipopolysaccharide-primed macrophages. Eicosanoid release from lipopolysaccharide-primed macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprostone; Eicosanoids; Female; Isoquinolines; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; Pertussis Toxin; Piperazines; SRS-A; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Interleukin 1 inhibits T cell receptor-mediated apoptosis in immature thymocytes.
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Calcium; CD4 Antigens; CD8 Antigens; Cells, Cultured; Cytosol; Diglycerides; DNA; Humans; Infant; Interleukin-1; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Regulation of S6 kinase activity in Madin-Darby canine kidney renal epithelial cells.
Topics: Amino Acid Sequence; Animals; Calcimycin; Cell Line; Chromatography, Ion Exchange; Cytosol; Dogs; Enzyme Activation; Epinephrine; Epithelium; Kidney; Kinetics; Molecular Sequence Data; Peptides; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Ribosomal Protein S6 Kinases; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate | 1990 |
Inhibition of protein kinase C by H-7 potentiates the release of oleic, linoleic and arachidonic acids in A23187-stimulated human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Fatty Acids; Humans; Isoquinolines; Linoleic Acid; Linoleic Acids; Neutrophils; Oleic Acid; Oleic Acids; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Adenine nucleotides modulate phosphatidylcholine metabolism in aortic endothelial cells.
Topics: Adenine Nucleotides; Animals; Aorta; Bradykinin; Calcimycin; Calcium; Cattle; Cholera Toxin; Choline; Down-Regulation; Endothelium, Vascular; Extracellular Space; GTP-Binding Proteins; In Vitro Techniques; Pertussis Toxin; Phosphatidylcholines; Protein Kinase C; Receptors, Purinergic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Vasopressin and norepinephrine stimulation of inositol phosphate accumulation in rat hepatocytes are modified differently by protein f1nase C and protein kinase A.
Topics: Animals; Calcimycin; Cells, Cultured; Glucagon; Inositol Phosphates; Liver; Norepinephrine; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1990 |
Epidermal growth factor enhances glomerular mesangial cell soluble phospholipase A2 activity.
Topics: Animals; Arginine Vasopressin; Calcimycin; Cells, Cultured; Chromatography, Ion Exchange; Cytosol; Diglycerides; Enzyme Activation; Epidermal Growth Factor; Glomerular Mesangium; Inositol; Inositol Phosphates; Kinetics; NAD; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Hepatocyte modulation of Kupffer cell prostaglandin E2 production in vitro.
Topics: Animals; Calcimycin; Cells, Cultured; Dinoprostone; Endotoxins; Kupffer Cells; Liver; Male; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
In vivo and in vitro assessment of porcine neutrophil activation responses to chemoattractants: flow cytometric evidence for the selective absence of formyl peptide receptors.
Topics: Animals; Calcimycin; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Complement C5a; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluoresceins; Humans; Ligands; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Formyl Peptide; Receptors, Immunologic; Swine; Tetradecanoylphorbol Acetate; Thiocyanates; Zymosan | 1990 |
The ratio of macrophage prostaglandin and leukotriene synthesis is determined by the intracellular free calcium level.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Dinoprostone; Drug Synergism; Enzyme Activation; In Vitro Techniques; Indomethacin; Macrophages; Manganese; Mice; Mice, Inbred DBA; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1990 |
Generation of platelet activating factor (PAF) by a human lung epithelial cell line.
Topics: Animals; Calcimycin; Cell Line; Chromatography, High Pressure Liquid; Epithelial Cells; Epithelium; Humans; Lung; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate | 1990 |
Differences between the mechanisms of action of heat-stable and heat-labile enterotoxins of Escherichia coli.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bacterial Toxins; Biological Transport, Active; Calcimycin; Calcium; Calmodulin; Chlorides; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Ileum; Isoquinolines; Mice; Piperazines; Protein Kinase C; Sodium; Tetradecanoylphorbol Acetate | 1990 |
1-naphthyl N-methyl carbamate effect on intra- and extracellular concentrations of arachidonic acid metabolites, and on the chemiluminescence generation by mouse peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Carbaryl; Cell Survival; Extracellular Space; Intracellular Fluid; Luminescent Measurements; Macrophages; Male; Mice; Oxidation-Reduction; Peritoneal Cavity; Tetradecanoylphorbol Acetate; Time Factors; Tritium; Zymosan | 1990 |
Release of a neutrophil-derived vasoconstrictor agent which augments platelet-induced contractions of blood vessels in vitro.
Topics: Animals; Aorta, Thoracic; Blood Platelets; Calcimycin; In Vitro Techniques; Lipoxygenase Inhibitors; Male; Molecular Weight; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Serotonin; Serotonin Antagonists; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1990 |
Regulatory effect of cholecystokinin on subsequent insulin binding to pancreatic acini.
Topics: Animals; Binding, Competitive; Calcimycin; Carbachol; Cell Membrane; Insulin; Kinetics; Male; Pancreas; Rats; Rats, Inbred Strains; Receptor, Insulin; Sincalide; Tetradecanoylphorbol Acetate | 1990 |
The T84 human colonic adenocarcinoma cell line produces mucin in culture and releases it in response to various secretagogues.
Topics: Adenocarcinoma; Calcimycin; Carbachol; Cell Line; Cholera Toxin; Colonic Neoplasms; Cystic Fibrosis; Histamine; Humans; Immunodiffusion; Immunoenzyme Techniques; Intestine, Small; Microscopy, Electron; Mucins; Prostaglandins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1990 |
Cell volume regulation by skate erythrocytes: role of potassium.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Calcimycin; Electric Fish; Erythrocytes; Hypotonic Solutions; Osmolar Concentration; Potassium; Skates, Fish; Tetradecanoylphorbol Acetate | 1990 |
In vitro beta 2-microglobulin (beta 2m) secretion by normal and leukaemic B-cells: effects of recombinant cytokines and evidence for a differential response to the combined stimulus of phorbol ester and calcium ionophore.
Topics: Adjuvants, Immunologic; B-Lymphocytes; beta 2-Microglobulin; Biological Factors; Bryostatins; Calcimycin; Cytokines; Humans; Immunoglobulin M; Lactones; Leukemia, B-Cell; Macrolides; Mitogens; Recombinant Proteins; Reference Values; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
The influence of calcium ionophore and activators of protein kinase C on steroid production by preovulatory ovarian follicles of the goldfish.
Topics: Animals; Calcimycin; Calcium; Cyprinidae; Diglycerides; Female; Glycerides; Goldfish; Ovarian Follicle; Ovary; Phorbol Esters; Protein Kinase C; Testosterone; Tetradecanoylphorbol Acetate | 1990 |
Pregnancy zone protein inhibits production of interleukin-2 but does not affect interleukin-2 receptor expression on T cell activation.
Topics: Calcimycin; DNA; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; In Vitro Techniques; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Pregnancy Proteins; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Effects of mitogenic agents upon glucocorticoid action in human tonsillar T-lymphocytes.
Topics: Calcimycin; Dexamethasone; Glucocorticoids; Humans; In Vitro Techniques; Leucine; Mitogens; Palatine Tonsil; Phytohemagglutinins; Protein Kinase C; Receptors, Glucocorticoid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine | 1990 |
Regulation of arachidonic acid release in mouse peritoneal macrophages. The role of extracellular calcium and protein kinase C.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Calcimycin; Calcium; Concanavalin A; Inositol Phosphates; Macrophages; Mice; Protein Kinase C; Secretory Rate; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Differential effects of lithocholate on rat neutrophil activation.
Topics: Animals; Calcimycin; Calcium; L-Lactate Dehydrogenase; Lithocholic Acid; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxides; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Platelet-derived growth factor stimulates non-mitochondrial Ca2+ uptake and inhibits mitogen-induced Ca2+ signaling in Swiss 3T3 fibroblasts.
Topics: Alkaloids; Animals; Biological Transport, Active; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Dinoprostone; Fibroblasts; Ionomycin; Kinetics; Mice; Mitogens; Phospholipid Ethers; Platelet-Derived Growth Factor; Protein Kinase C; Recombinant Proteins; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1990 |
Inhibitory and stimulatory effects of phorbol ester on vasopressin-induced cellular responses in cultured rat aortic smooth muscle cells.
Topics: Alkaloids; Animals; Aorta; Arginine Vasopressin; Calcimycin; Calcium; Cells, Cultured; Cytosol; Drug Synergism; Enzyme Activation; Epoprostenol; Female; Inositol 1,4,5-Trisphosphate; Kinetics; Muscle, Smooth, Vascular; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Modulation of RNA expression by intracellular calcium. Existence of a threshold calcium concentration for induction of VL30 RNA by epidermal growth factor, endothelin, and protein kinase C.
Topics: Animals; Benzofurans; Calcimycin; Calcium; Carrier Proteins; Cell Line; Egtazic Acid; Endothelins; Endothelium, Vascular; Epidermal Growth Factor; Fluorescent Dyes; Fura-2; Inositol Phosphates; Peptides; Peptidylprolyl Isomerase; Protein Kinase C; Rats; Retroviridae; RNA, Viral; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1990 |
Novel ATP-binding heat-inducible protein of Mr = 37,000 that is sensitive to transformation in BALB/3T3 cells.
Topics: 2,2'-Dipyridyl; Adenosine Triphosphate; Animals; Arsenic; Arsenites; Calcimycin; Carrier Proteins; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum Chaperone BiP; Fibroblasts; Heat-Shock Proteins; Methionine; Mice; Mice, Inbred BALB C; Precipitin Tests; Sepharose; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Tunicamycin | 1990 |
Enhancement of thrombin- and ionomycin-stimulated prostacyclin and platelet-activating factor production in cultured endothelial cells by a tumor-promoting phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Ionomycin; Isoquinolines; Phorbol Esters; Phospholipases A; Phospholipases A2; Piperazines; Platelet Activating Factor; Prostaglandin D2; Prostaglandins H; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Stimulated platelets release factor(s) affecting the in vitro response of human polymorphonuclear cells.
Topics: Blood Platelets; Calcimycin; Concanavalin A; Humans; Luminescent Measurements; Luminol; Lysosomes; Neutrophils; Oxygen; Platelet Activation; Tetradecanoylphorbol Acetate; Thrombin; Zymosan | 1990 |
Inducible production of macrophage colony-stimulating factor (CSF-1) by malignant and normal human T cells.
Topics: Antigens, Differentiation, T-Lymphocyte; Blotting, Northern; Calcimycin; Cells, Cultured; Colony-Forming Units Assay; Colony-Stimulating Factors; Humans; Interleukin-1; Leukemia, T-Cell; Macrophage Colony-Stimulating Factor; Monocytes; Phenotype; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
Expression of proto-oncogene c-jun during differentiation of B-chronic lymphocytic leukemia.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bryostatins; Calcimycin; Cell Differentiation; Enzyme Activation; Gene Expression; Humans; Isoquinolines; Kinetics; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Piperazines; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogenes; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Endocytosis and degradation of ovine prolactin by Nb2 lymphoma cells: characterization and effects of agents known to alter prolactin-induced mitogenesis.
Topics: Amiloride; Animals; Calcimycin; Cell Division; Cell Membrane; Chloroquine; Endocytosis; Kinetics; Leupeptins; Lymphoma; Methylamines; Mitosis; Monensin; Prolactin; Rats; Receptors, Prolactin; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Production of hydrogen peroxide by rabbit articular chondrocytes. Enhancement by cytokines.
Topics: Animals; Calcimycin; Cartilage, Articular; Catalase; Concanavalin A; Flow Cytometry; Hydrogen Peroxide; Interferon-gamma; Macrophages; Oxidation-Reduction; Pulmonary Alveoli; Rabbits; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1990 |
Effects of phorbol esters and calcium ionophore on nonspecific cytotoxic cells.
Topics: Animals; Calcimycin; Catfishes; Cell Line; Cytotoxicity, Immunologic; Humans; Phorbol Esters; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Calcitonin inhibits basal and thyrotropin-releasing hormone-induced release of prolactin from anterior pituitary cells: evidence for a selective action exerted proximal to secretagogue-induced increases in cytosolic Ca2+.
Topics: Animals; Calcimycin; Calcitonin; Calcium; Colforsin; Cytosol; Female; In Vitro Techniques; Kinetics; Pituitary Gland, Anterior; Prolactin; Rats; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Time Factors; Vasoactive Intestinal Peptide | 1990 |
IL-2. A cofactor for induction of activated macrophage resistance to infection.
Topics: Animals; Calcimycin; Immunity, Innate; Infections; Interferon-gamma; Interleukin-2; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred Strains; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1990 |
H(+)-induced vasodilation of rat aorta is mediated by alterations in intracellular calcium sequestration.
Topics: Acetylcholine; Acidosis; Animals; Aorta, Thoracic; Calcimycin; Calcium; Egtazic Acid; Endothelium, Vascular; Hydrogen-Ion Concentration; In Vitro Techniques; Models, Biological; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasodilation | 1990 |
A specific defect of prosolin phosphorylation in T cell leukemic lymphoblasts is associated with impaired down-regulation of DNA synthesis.
Topics: Calcimycin; Calcium; DNA; Down-Regulation; Humans; Leukemia-Lymphoma, Adult T-Cell; Lymphocyte Activation; Lymphocytes; Neoplasm Proteins; Peptide Fragments; Phosphoproteins; Phosphorylation; Tetradecanoylphorbol Acetate | 1990 |
Activation of phospholipase D in normodense human eosinophils.
Topics: Calcimycin; Complement C5a; Dose-Response Relationship, Drug; Enzyme Activation; Eosinophils; Ethanol; Glycerophospholipids; Humans; Kinetics; Lymphocyte Activation; Phosphatidic Acids; Phospholipase D; Phospholipases; Tetradecanoylphorbol Acetate | 1990 |
Involvement of external calcium in the release of arachidonic acid by mouse peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Extracellular Space; Female; In Vitro Techniques; Macrophages; Mice; Peritoneal Cavity; Tetradecanoylphorbol Acetate | 1990 |
Aequorin-detected calcium changes in stimulated thrombasthenic platelets. Aggregation-dependent calcium movement in response to ADP.
Topics: Adenosine Diphosphate; Aequorin; Blood Platelet Disorders; Blood Platelets; Calcimycin; Calcium; Collagen; Humans; In Vitro Techniques; Luminescent Proteins; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombasthenia; Thrombin | 1990 |
Parathyroid hormone increases thiol proteinase activity by activation of protein kinase C in cultured kidney tubule cells (OK).
Topics: Animals; Calcimycin; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; In Vitro Techniques; Kidney Tubules; Leucine; Opossums; Parathyroid Hormone; Peptide Hydrolases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Histidine decarboxylase in human basophilic leukemia (KU-812-F) cells. Characterization and induction by phorbol myristate acetate.
Topics: Alkaloids; Calcimycin; Carboxy-Lyases; Cycloheximide; Enzyme Induction; Histidine Decarboxylase; Humans; Leukemia, Basophilic, Acute; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Ability of the Ca2+ ionophores A23187 and ionomycin to mimic some of the effects of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate on hydroperoxide production, ornithine decarboxylase activity, and DNA synthesis in mouse epidermis in vivo.
Topics: Animals; Calcimycin; Cell Differentiation; DNA; Female; Hydrogen Peroxide; Ionomycin; Mice; Ornithine Decarboxylase; Skin; Tetradecanoylphorbol Acetate | 1990 |
Effects of intracellular calcium on proximal bicarbonate absorption.
Topics: Absorption; Angiotensin II; Animals; Bicarbonates; Calcimycin; Drug Interactions; Intracellular Membranes; Kidney Tubules, Proximal; Male; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Response to IL-6 stimulation of human hepatoblastoma cells: production of pancreatic secretory trypsin inhibitor.
Topics: Animals; Biological Factors; Calcimycin; Colforsin; Cycloheximide; Cytokines; Humans; Interleukin-6; Lipopolysaccharides; Liver Neoplasms, Experimental; Lymphocyte Activation; Tetradecanoylphorbol Acetate; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tumor Cells, Cultured | 1990 |
Regulation of protein phosphorylation in ocular ciliary epithelial cells by A, C and Ca2+/calmodulin-dependent protein kinases.
Topics: Adenylyl Cyclases; Calcimycin; Cells, Cultured; Ciliary Body; Epithelium; Eye Proteins; Humans; Isoproterenol; Peptide Mapping; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1990 |
Stimulation of bovine luteal oxytocin secretion in vitro by a phorbol ester and calcium ionophore.
Topics: Animals; Calcimycin; Cattle; Corpus Luteum; Culture Techniques; Female; Oxytocin; Progesterone; Tetradecanoylphorbol Acetate | 1990 |
The simultaneous acute release of tissue-type plasminogen activator and von Willebrand factor in the perfused rat hindleg region.
Topics: Animals; Calcimycin; Calcium; Enzyme-Linked Immunosorbent Assay; Hindlimb; Male; Perfusion; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors; Tissue Plasminogen Activator; von Willebrand Factor | 1990 |
Influence of extracellular calcium on the metabolism of arachidonic acid in alveolar macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cattle; Egtazic Acid; Indomethacin; Macrophages; Phospholipases A; Phospholipases A2; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Accommodation of protein synthesis to chronic deprivation of intracellular sequestered calcium. A putative role for GRP78.
Topics: Animals; Calcimycin; Calcium; Carrier Proteins; Cell Line; Dithiothreitol; Egtazic Acid; Electrophoresis, Gel, Two-Dimensional; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Kinetics; Leucine; Methionine; Molecular Chaperones; Molecular Weight; Neoplasm Proteins; Protein Biosynthesis; Tetradecanoylphorbol Acetate | 1990 |
Mechanism whereby different anti-oxidants and lipoxigenase pathway inhibitors suppress IL2 synthesis.
Topics: Animals; Antioxidants; Calcimycin; Calcium; Cell Aggregation; Concanavalin A; Hydrogen-Ion Concentration; Interleukin-2; Lipoxygenase Inhibitors; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Acute inhibitory effect of follicle-stimulating hormone-suppressing protein (FSP) on gonadotropin-releasing hormone-stimulated gonadotropin secretion in cultured rat anterior pituitary cells.
Topics: Animals; Calcimycin; Cells, Cultured; Diterpenes; Enzyme Activation; Follicle Stimulating Hormone; Follistatin; Glycoproteins; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Melitten; Phospholipases A; Phospholipases A2; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Transcriptional down-regulation of c-myc expression by protein synthesis-dependent and -independent pathways in a human T lymphoblastic tumor cell line.
Topics: Calcimycin; Calcium; Cycloheximide; Depression, Chemical; Dimethyl Sulfoxide; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-myb; Proto-Oncogene Proteins c-myc; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Naturally activated and resting T cells differ in their activation requirements for growth and secretory activities.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Dose-Response Relationship, Immunologic; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Receptor-mediated stimulation of taurocholate efflux from the rat hepatocyte and the ex vivo perfused rat liver.
Topics: Animals; Arginine Vasopressin; Bile Acids and Salts; Calcimycin; Cell Membrane; Glycocholic Acid; Liver; Male; Perfusion; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Vasopressin; Taurocholic Acid; Tetradecanoylphorbol Acetate | 1990 |
TPA induction of EL4 resistance to macrophage-released TNF: role of ADP-ribosylation in tumoricidal activities of TNF and other factors.
Topics: Animals; Antibodies; Benzamides; Calcimycin; Cytotoxicity, Immunologic; Cytotoxins; Down-Regulation; Genetic Variation; Macrophage Activation; Mice; Niacinamide; Pertussis Toxin; Poly(ADP-ribose) Polymerase Inhibitors; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virulence Factors, Bordetella | 1990 |
The leukocyte-common antigen (CD45) complex and B-lymphocyte activation.
Topics: Antibodies, Anti-Idiotypic; Antigens, CD; Antigens, Differentiation; B-Lymphocytes; Calcimycin; Histocompatibility Antigens; Humans; Immunoglobulin M; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Common Antigens; Lymphocyte Activation; Molecular Weight; Palatine Tonsil; Tetradecanoylphorbol Acetate | 1990 |
Activation of cord T lymphocytes. II. Cellular and molecular analysis of the defective response induced by anti-CD3 monoclonal antibody.
Topics: Antigen-Presenting Cells; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Fetal Blood; Gene Expression; Humans; In Vitro Techniques; Interleukin-1; Interleukin-2; Lymphocyte Activation; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; RNA, Messenger; Solubility; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Evidence for the existence of distinct heterogeneity among the peripheral CD4-CD8- T cells from MRL-lpr/lpr mice based on the expression of the J11d marker, activation requirements, and functional properties.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antigens, Ly; Autoimmune Diseases; Calcimycin; CD4 Antigens; CD8 Antigens; Cell Differentiation; Cytotoxicity, Immunologic; Flow Cytometry; Interleukin-2; Interleukin-4; Interleukin-6; Lymphocyte Activation; Mice; Mice, Mutant Strains; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Modulation of mast cell responses to adenosine by agents that alter protein kinase C activity.
Topics: Adenosine; Animals; beta-N-Acetylhexosaminidases; Calcimycin; Cells, Cultured; Cytosol; Diglycerides; Enzyme Activation; Glycerides; Mast Cells; Mice; Mice, Inbred BALB C; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1990 |
IL-3 production as a function of age and its correlation with splenomegaly: age versus disease-related change.
Topics: Aging; Animals; Calcimycin; Cells, Cultured; Female; Gene Expression Regulation; Interleukin-3; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Splenomegaly; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1990 |
Polymorphism of age-related changes in interleukin (IL) production: differential changes of T helper subpopulations, synthesizing IL 2, IL 3 and IL 4.
Topics: Aging; Animals; Calcimycin; Concanavalin A; Female; Interleukin-2; Interleukin-3; Interleukin-4; Mice; Mice, Inbred Strains; Polymorphism, Genetic; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1990 |
Thromboxane release by lymphokine-differentiated U937 human monocytic cells: response to platelet-activating factor (PAF) and chemotactic peptide (FMLP) but not to low affinity IGE-receptor (Fc epsilon RII/CD23) occupation.
Topics: Antibodies, Anti-Idiotypic; Antigens, Differentiation, B-Lymphocyte; Calcimycin; Drug Synergism; Humans; Immunoglobulin E; Interferon-gamma; Interleukin-4; Leukemia, Monocytic, Acute; Lymphokines; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Binding; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate; Thromboxane B2; Tumor Cells, Cultured | 1990 |
Regulation of adhesion of mouse bone marrow-derived mast cells to laminin.
Topics: Animals; Antigens; Antigens, Differentiation, B-Lymphocyte; Bone Marrow Cells; Calcimycin; Cell Adhesion; Laminin; Mast Cells; Mice; Protein Kinase C; Protein Kinases; Receptors, Fc; Receptors, IgE; Temperature; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1990 |
Bacterial lipopolysaccharide enhances polymorphonuclear leukocyte function independent of changes in intracellular calcium.
Topics: Aminoquinolines; Calcimycin; Calcium; Calcium Channel Blockers; Egtazic Acid; Enzyme Activation; Gallic Acid; Humans; Hydrogen Peroxide; Lipopolysaccharides; Neutrophils; Phagocytosis; Protein Kinase C; Receptors, Complement; Receptors, Complement 3b; Second Messenger Systems; Tetradecanoylphorbol Acetate; Trifluoperazine | 1990 |
[Inhibition of phorbol ester and A23187-stimulated prostaglandins synthesis in macrophages by anisodamine].
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Macrophages; Mice; Peritoneal Cavity; Solanaceous Alkaloids; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
Studies of the mechanism of natural killer (NK) degranulation and cytotoxicity.
Topics: Animals; Calcimycin; Calcium; Cell Degranulation; Cytotoxicity, Immunologic; Diglycerides; Granzymes; Killer Cells, Natural; Neomycin; Phosphatidylinositols; Protein Kinase C; Rats; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1990 |
Action sites of antiallergic drugs on human neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Histamine Antagonists; Humans; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Evaluation of synthetic sphingosine, lysosphingolipids and glycosphingolipids as inhibitors of functional responses of human neutrophils.
Topics: Antigens, CD; Calcimycin; Cell Aggregation; Cerebrosides; Galactosylceramides; Globosides; Glycolipids; Glycosphingolipids; Humans; Lactosylceramides; Leukotriene B4; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Psychosine; Sphingolipids; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate; Trihexosylceramides | 1990 |
How flavonoids inhibit the generation of luminol-dependent chemiluminescence by activated human neutrophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Flavanones; Flavonoids; Flavonols; Hesperidin; Humans; Luminescent Measurements; Luminol; Luteolin; Neutrophils; Oxygen; Peroxidase; Pyridazines; Quercetin; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase | 1990 |
Involvement of the phospholipase C second messenger system in the regulation of steroidogenesis in small bovine luteal cells.
Topics: Animals; Bucladesine; Calcimycin; Cattle; Corpus Luteum; Cyclic AMP; Female; In Vitro Techniques; Luteal Cells; Luteinizing Hormone; Progesterone; Second Messenger Systems; Steroids; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1990 |
Regulation of oxytocin secretion by the ovine corpus luteum: effect of activators of protein kinase C.
Topics: Animals; Bucladesine; Calcimycin; Corpus Luteum; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Female; In Vitro Techniques; Oxytocin; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Sheep; Tetradecanoylphorbol Acetate; Thiazoles; Type C Phospholipases | 1990 |
U937 and THP-1 cells do not release LTB4, LTC4, or LTD4 in response to A23187.
Topics: Calcimycin; Humans; In Vitro Techniques; Interferon-gamma; Leukotriene B4; Monocytes; SRS-A; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Induction of the oxidative response and of concanavalin A-binding capacity in maturing human U937 cells.
Topics: Calcimycin; Cell Differentiation; Cell Line; Concanavalin A; Humans; Kinetics; Lymphoma, Large B-Cell, Diffuse; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Concanavalin A; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zymosan | 1990 |
Independent control of the production of insulin-like growth factor I and its binding protein by cultured testicular cells.
Topics: Animals; Calcimycin; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Insulin-Like Growth Factor I; Leydig Cells; Luteinizing Hormone; Male; Receptors, Cell Surface; Receptors, Somatomedin; Sertoli Cells; Sheep; Somatomedins; Testis; Tetradecanoylphorbol Acetate | 1990 |
Dietary linoleate supplementation modulates formyl-peptide receptor expression and functional responses of rat neutrophils.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate 5-Lipoxygenase; Calcimycin; Calcium; Dietary Fats; Ionomycin; Leukotriene B4; Linoleic Acid; Linoleic Acids; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Rats; Rats, Inbred Strains; Receptors, Formyl Peptide; Receptors, Immunologic; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
Coupled and uncoupled induction of fos and jun transcription by different second messengers in cells of hematopoietic origin.
Topics: Calcimycin; Calcium; Cell Line; Cyclic AMP; DNA-Binding Proteins; Enzyme Activation; Hematopoietic Stem Cells; Humans; Kinetics; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Type C Phospholipases | 1990 |
Protein kinase C is involved in desensitization of muscarinic receptors induced by phorbol esters but not by receptor agonists.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carbachol; Cyclic GMP; Down-Regulation; Isoquinolines; Mice; N-Methylscopolamine; Neuroblastoma; Parasympathomimetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Receptors, Muscarinic; Scopolamine Derivatives; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Platelet activating factor stimulates cyclo-oxygenase activity in guinea pig eosinophils. Concerted biosynthesis of thromboxane A2 and E-series prostaglandins.
Topics: Animals; Azepines; Calcimycin; Calcium; Complement C5a; Cyclooxygenase Inhibitors; Enzyme Activation; Eosinophils; Flurbiprofen; Guinea Pigs; Imidazoles; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Triazines; Triazoles | 1990 |
Prostaglandin and leukotriene production by alveolar type II cells in vitro.
Topics: Animals; Calcimycin; Cells, Cultured; Eicosanoids; Kinetics; Leukotriene B4; Leukotrienes; Lung; Macrophages; Male; Prostaglandins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Evidence for the calcium-dependent activation of phospholipase D in thrombin-stimulated human erythroleukaemia cells.
Topics: Adenosine Diphosphate; Calcimycin; Calcium; Cell Line; Enzyme Activation; Epinephrine; Glycerophospholipids; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylinositols; Phospholipase D; Phospholipases; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1990 |
Transcriptional regulation of the interleukin 2 gene by glucocorticoid hormones. Role of steroid receptor and antigen-responsive 5'-flanking sequences.
Topics: Animals; Avian Sarcoma Viruses; Calcimycin; Cell Nucleus; Chloramphenicol O-Acetyltransferase; Dexamethasone; DNA, Recombinant; Gene Expression Regulation; Human T-lymphotropic virus 1; Humans; Hylobates; Interleukin-2; Mammary Tumor Virus, Mouse; Mice; Promoter Regions, Genetic; Receptors, Glucocorticoid; Regulatory Sequences, Nucleic Acid; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Simian virus 40; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1990 |
Control of bovine uterine prostaglandin F2 alpha release in vitro.
Topics: Animals; Arachidonic Acids; Bucladesine; Calcimycin; Carcinogens; Cattle; Cholera Toxin; Cycloheximide; Dibutyryl Cyclic GMP; Diglycerides; Dinoprost; Endometrium; Female; Nucleotides, Cyclic; Oxytocin; Phorbol Esters; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Uterus | 1990 |
Progesterone modulation of gonadotropin secretion by dispersed rat pituitary cells in culture. III. A23187, cAMP, phorbol ester and DiC8-stimulated luteinizing hormone release.
Topics: Animals; Calcimycin; Cells, Cultured; Cholera Toxin; Cyclic AMP; Diglycerides; Estradiol; Female; Luteinizing Hormone; Pituitary Gland, Anterior; Pituitary Hormone-Releasing Hormones; Progesterone; Prolactin; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Effect of inhibin on activators of protein kinase-C and calcium-mobilizing agents which stimulate secretion of gonadotropins in vitro: implication of a postgonadotropin-releasing hormone receptor effect of inhibin on gonadotropin release.
Topics: Adrenocorticotropic Hormone; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Diterpenes; Enzyme Activation; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Inhibins; Luteinizing Hormone; Male; Melitten; Pituitary Gland, Anterior; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, LHRH; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Cocaine and its derivatives blunt neutrophil functions without influencing phosphorylation of a 47-kilodalton component of the reduced nicotinamide-adenine dinucleotide phosphate oxidase.
Topics: Anesthetics, Local; Calcimycin; Cell Aggregation; Cell Degranulation; Cocaine; Glucuronidase; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; Neutrophils; Receptors, Complement; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Up-Regulation | 1990 |
Accessory signals in T-T cell interactions between antigen- and alloantigen-specific, human memory T cells generated in vitro.
Topics: Antibodies, Monoclonal; Antigen-Presenting Cells; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD28 Antigens; Cell Communication; Cell Line; Humans; Immunologic Memory; Interleukin-4; Isoantigens; Lymphocyte Activation; Recombinant Proteins; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Effects of Ca2+ ionophore A23187, 1,2-dioctanoylglycerol, and dibutyryl cAMP on the activity and expression of ornithine decarboxylase in guinea pig lymphocytes.
Topics: Animals; Bucladesine; Calcimycin; Cells, Cultured; Diglycerides; Glycerides; Guinea Pigs; Lymphocytes; Ornithine Decarboxylase; RNA, Messenger; Tetradecanoylphorbol Acetate | 1990 |
Superoxide anion generation in the liver during the early stage of endotoxemia in rats.
Topics: Animals; Calcimycin; Endotoxins; Kupffer Cells; Lipopolysaccharides; Liver; Male; Monocytes; Neutropenia; Neutrophils; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Granulosa cells from pig follicles of different sizes demonstrate maturational differences in their steroidogenic responses to FSH, calcium ionophore A23187, and phorbol diester.
Topics: Animals; Bucladesine; Calcimycin; Cells, Cultured; Colforsin; Estradiol; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Granulosa Cells; Progesterone; Stimulation, Chemical; Swine; Tetradecanoylphorbol Acetate | 1990 |
Orthovanadate and fluoroaluminate stimulate inositol phosphate production and in vitro ovulation in goldfish (Carassius auratus) follicles.
Topics: Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Calcimycin; Chlorides; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Cyprinidae; Dinoprost; Female; Goldfish; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Ovarian Follicle; Ovulation; Sodium Fluoride; Tetradecanoylphorbol Acetate; Vanadates | 1990 |
Cyclic AMP and calcium in mouse mammary tumour virus expression: effects and post-transcriptional site of action.
Topics: Animals; Calcimycin; Calcium; Calmodulin; Cells, Cultured; Cyclic AMP; Epithelium; Female; Glycoproteins; Mammary Glands, Animal; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H; Organ Culture Techniques; Protein Kinase C; Protein Processing, Post-Translational; RNA, Viral; Tetradecanoylphorbol Acetate; Viral Proteins; Virus Activation | 1990 |
Calcium ionophore potentiates chemotactic peptide and platelet activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.
Topics: Calcimycin; Drug Synergism; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Radioimmunoassay; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
Phorbol ester induces inhibition of arachidonate incorporation into phospholipids in human neutrophils.
Topics: Acyltransferases; Arachidonic Acids; Calcimycin; Coenzyme A Ligases; Enzyme Activation; Humans; Leukotriene B4; Neutrophils; Oleic Acid; Oleic Acids; Phospholipids; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
Calcium ionophore but not phorbol ester promotes eicosanoids release by proliferating interleukin-3-dependent bone marrow cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bone Marrow Cells; Calcimycin; Calcium; Cell Division; Clone Cells; Dinoprostone; DNA; Female; Hematopoietic Stem Cells; Interleukin-3; Leukotriene B4; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Mice, Inbred CBA; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Regulation of platelet-activating factor receptor and PAF receptor-mediated arachidonic acid release by protein kinase C activation in rat Kupffer cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Dimethyl Sulfoxide; Down-Regulation; Enzyme Activation; Kinetics; Kupffer Cells; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1990 |
Differential inhibition of T cell receptor signal transduction and early activation events by a selective inhibitor of protein-tyrosine kinase.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Calcium; CD3 Complex; Genistein; Humans; Interleukin-2; Isoflavones; Lectins, C-Type; Lymphocyte Activation; Phosphatidylinositols; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
Selective inhibition of human neutrophil functional responsiveness by erbstatin, an inhibitor of tyrosine protein kinase.
Topics: Calcimycin; Chemotactic Factors; Humans; Hydroquinones; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Interleukin-1 synergy with phosphoinositide pathway agonists for induction of interleukin-2 gene expression: molecular basis of costimulation.
Topics: Animals; Base Sequence; Calcimycin; Cell Line; Chloramphenicol O-Acetyltransferase; Drug Synergism; Gene Expression; Interleukin-1; Interleukin-2; Mice; Molecular Sequence Data; NF-kappa B; Oligonucleotide Probes; Phosphatidylinositols; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Recombinant Proteins; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1990 |
Regulation of Ki-ras expression in Reuber H35 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bucladesine; Calcimycin; Calcium; Cell Line; Diglycerides; DNA Probes; Egtazic Acid; Gene Expression Regulation, Neoplastic; Genes, ras; Glucagon; Isoquinolines; Kinetics; Liver Neoplasms, Experimental; Piperazines; Protein Kinase Inhibitors; Rats; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Verapamil | 1990 |
cAMP inhibits induction of interleukin 2 but not of interleukin 4 in T cells.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Humans; Interleukin-1; Interleukin-2; Interleukin-4; Plasmids; Promoter Regions, Genetic; Recombinant Proteins; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1990 |
Effect of the spin trap 5,5 dimethyl-1-pyrroline-N-oxide (DMPO) on human neutrophil function: novel inhibition of neutrophil stimulus-response coupling?
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Concanavalin A; Cyclic N-Oxides; Cytochrome c Group; Cytoplasmic Granules; Humans; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Spin Labels; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1990 |
Inhibition of atrial natriuretic peptide-induced cGMP accumulation by purinergic agonists in FRTL-5 thyroid cells. Involvement of both pertussis toxin-sensitive and insensitive mechanisms.
Topics: Adenosine Deaminase; Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Calcimycin; Calcium; Cell Line; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol Phosphates; Norepinephrine; Pertussis Toxin; Phenylisopropyladenosine; Phosphodiesterase Inhibitors; Rats; Receptors, Purinergic; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
Effects of beta-adrenergic receptor activation, cholera toxin and forskolin on human natural killer cell function.
Topics: Adenosine Diphosphate Ribose; Calcimycin; Cell Line; Cell Membrane; Cholera Toxin; Colforsin; Cyclic AMP; Cytotoxicity, Immunologic; Epinephrine; Humans; In Vitro Techniques; Isoproterenol; Killer Cells, Natural; Kinetics; Lymphocyte Activation; Membrane Proteins; NAD; Phosphorus Radioisotopes; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1990 |
Inhibition of polymorphonuclear leukocyte function by Legionella pneumophila exoproducts.
Topics: Calcimycin; Chemotaxis, Leukocyte; Ethyl Methanesulfonate; Legionella; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Potential roles of Mg2+ and Ca2+ in NADPH oxidase dependent superoxide anion synthesis by human neutrophils.
Topics: Calcimycin; Calcium; Cells, Cultured; Humans; Magnesium; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Differential regulation of 5-lipoxygenase and cyclo-oxygenase pathways of arachidonate metabolism in rat peritoneal leukocytes.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Female; In Vitro Techniques; Leukocytes; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Prostaglandin-Endoperoxide Synthases; Radioimmunoassay; Rats; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
Phorbol 12-myristate 13-acetate, A23187 and L-adrenaline inhibit phospholipid methylation in human monocytes and lymphocytes. Inhibition is independent of oxyradical production and phospholipid hydrolysis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Epinephrine; Free Radicals; Humans; Hydrolysis; Isoquinolines; Lymphocytes; Methylation; Monocytes; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Piperazines; Protein Kinase Inhibitors; S-Adenosylmethionine; Sodium Fluoride; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
[The effect of phorbol esters and Ca2+ ions on the process of autophosphorylation of epidermal growth factor receptor in vivo].
Topics: Calcimycin; Calcium; ErbB Receptors; Humans; Phosphorylation; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1990 |
Pathways of signal transduction in teleost nonspecific cytotoxic cells.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Catfishes; Cell Cycle; Cytotoxicity, Immunologic; Female; Gene Expression Regulation; Humans; Killer Cells, Natural; Male; Rats; Receptors, Immunologic; Signal Transduction; Tetradecanoylphorbol Acetate | 1990 |
Analysis of the primary signals required for activation of the mitogenic pathway in murine thymocytes from protein phosphorylation patterns.
Topics: Animals; Calcimycin; Colforsin; Concanavalin A; Diglycerides; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Isoelectric Point; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Molecular Weight; Phosphoproteins; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Regulation of HLA class II molecule expressions by IFN-gamma. The signal transduction mechanism in glioblastoma cell lines.
Topics: Biological Transport; Blotting, Northern; Calcimycin; Calcium; Cell Compartmentation; Enzyme Activation; Gene Expression Regulation, Neoplastic; Glioma; HLA-D Antigens; HLA-DP Antigens; HLA-DR Antigens; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1990 |
Regulation of human renin expression in chorion cell primary cultures.
Topics: Calcimycin; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Chorion; Colforsin; Enzyme Precursors; Female; Gene Expression Regulation, Enzymologic; Humans; Kinetics; Plasmids; Renin; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection | 1990 |
Potential mediation of prostaglandin E2 release from isolated human parietal cells by protein kinase C.
Topics: Calcimycin; Calmodulin; Carbachol; Cell Separation; Diglycerides; Dinoprostone; Drug Synergism; Enzyme Activation; Gastric Mucosa; Humans; Parietal Cells, Gastric; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1990 |
Response patterns of hairy cell leukemia to B-cell mitogens and growth factors.
Topics: B-Lymphocytes; Calcimycin; Cell Adhesion; DNA; Fluorescent Antibody Technique; Growth Substances; Humans; Immunohistochemistry; Interferon Type I; Interleukin-4; Interleukin-5; Interleukin-6; Leukemia, Hairy Cell; Mitogens; Phenotype; Rosette Formation; Staphylococcus aureus; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
The NGFI-B protein, an inducible member of the thyroid/steroid receptor family, is rapidly modified posttranslationally.
Topics: Adrenal Gland Neoplasms; Animals; Calcimycin; Cell Line; DNA-Binding Proteins; Epidermal Growth Factor; Fibroblast Growth Factor 2; Multigene Family; Nerve Growth Factors; Nuclear Receptor Subfamily 4, Group A, Member 1; Pheochromocytoma; Phosphorylation; Protein Processing, Post-Translational; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Receptors, Thyroid Hormone; Tetradecanoylphorbol Acetate; Transcription Factors | 1990 |
Effects of the protein kinase inhibitors, staurosporine and K-252a, on PGI2 production by rat liver cells (the C-9 cell line).
Topics: 6-Ketoprostaglandin F1 alpha; Alkaloids; Animals; Calcimycin; Carbazoles; Cell Line; Drug Synergism; Epoprostenol; Indole Alkaloids; Liver; Platelet Activating Factor; Protein Kinase C; Radioimmunoassay; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Dissociation between inositol polyphosphate production and mitogenesis in mouse thymocytes.
Topics: Animals; Calcimycin; Cell Division; Concanavalin A; DNA Replication; Inositol Phosphates; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Phytohemagglutinins; Receptors, Mitogen; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1990 |
Estradiol increases phosphorylation of the 90 kDa heat shock protein not associated with estradiol receptor in MCF-7 cells in culture.
Topics: Blotting, Western; Breast Neoplasms; Calcimycin; Colforsin; Estradiol; Heat-Shock Proteins; Humans; Phosphorylation; Receptors, Estrogen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Effects of isoproterenol on histamine release induced from monodispersed guinea-pig lung cells by different secretagogues.
Topics: Animals; Antigens; Bucladesine; Calcimycin; Calcium; Colforsin; Diterpenes; Female; Guinea Pigs; Histamine Release; In Vitro Techniques; Isoproterenol; Lung; Ovalbumin; Tetradecanoylphorbol Acetate | 1985 |
Role of free cytosolic calcium in secretagogue-stimulated amylase release from dispersed acini from guinea pig pancreas.
Topics: Amylases; Animals; Bombesin; Calcimycin; Calcium; Carbachol; Guinea Pigs; In Vitro Techniques; Kinetics; Pancreas; Pancreatic Juice; Sincalide; Tetradecanoylphorbol Acetate | 1985 |
Molecular events in B cell activation. I. Signals required to stimulate G0 to G1 transition of resting B lymphocytes.
Topics: Animals; B-Lymphocytes; Calcimycin; Calcium; Cell Cycle; DNA Replication; Female; Interphase; Lymphocyte Activation; Macrophages; Mice; Protein Kinase C; Protein Kinases; Receptors, Antigen, B-Cell; RNA; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
Hydrocortisone inhibits phorbol ester stimulated release of histamine and arachidonic acid from rat mast cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Histamine Release; Hydrocortisone; Mast Cells; Phorbols; Rats; Somatostatin; Tetradecanoylphorbol Acetate | 1985 |
Mechanism of calcium ionophore A23187-induced priming of bone marrow-derived macrophages for tumor cell killing: relationship to priming by interferon.
Topics: Animals; Bone Marrow Cells; Calcimycin; Cytotoxicity, Immunologic; Diglycerides; Dose-Response Relationship, Drug; Interferons; Lipopolysaccharides; Macrophages; Male; Mice; Neoplasms, Experimental; Phorbols; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1985 |
Activation of tracheal smooth muscle contraction: synergism between Ca2+ and activators of protein kinase C.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Cattle; Colforsin; Diterpenes; Drug Synergism; Enzyme Activation; Ethers; In Vitro Techniques; Ionomycin; Muscle Contraction; Muscle, Smooth; Nifedipine; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Trachea | 1985 |
Phorbol ester stimulates amylase secretion from rat parotid cells.
Topics: Amylases; Animals; Bucladesine; Calcimycin; Calcium; Carbachol; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Exocytosis; Parotid Gland; Phorbols; Protein Kinase C; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
1,2-Diacylglycerol, protein kinase C, and pancreatic enzyme secretion.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amylases; Animals; Arachidonic Acid; Arachidonic Acids; Bombesin; Calcimycin; Carbachol; Dibutyryl Cyclic GMP; Diglycerides; Glycerides; Guinea Pigs; In Vitro Techniques; Isoquinolines; Kinetics; Pancreas; Piperazines; Protein Kinase C; Sincalide; Tetradecanoylphorbol Acetate; Tetragastrin | 1986 |
Phorbol esters and calcium ionophore can prime murine peritoneal macrophages for tumor cell destruction.
Topics: Animals; Calcimycin; Calcium; Cytotoxicity, Immunologic; Egtazic Acid; Interferon-gamma; Ion Channels; Macrophage Activation; Mast-Cell Sarcoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Peritoneal Cavity; Phorbols; Tetradecanoylphorbol Acetate | 1986 |
Comparative studies of mediator release from guinea pig lung mast cells and basophils.
Topics: Animals; Antibodies; Antigens; Basophils; Calcimycin; Cell Fractionation; Centrifugation, Density Gradient; Concanavalin A; Female; gamma-Globulins; Guinea Pigs; Histamine Release; Immunization; Lung; Mast Cells; Ovalbumin; Sheep; SRS-A; Tetradecanoylphorbol Acetate | 1986 |
Characteristics of the effect of phorbol ester on rat mast cells: interaction with anti-IgE.
Topics: Animals; Antibodies, Anti-Idiotypic; Calcimycin; Calcium; Histamine Release; Immunoglobulin E; In Vitro Techniques; Male; Mast Cells; Phorbols; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Inhibitory effects of antithyroid drugs on oxygen radical formation in human neutrophils.
Topics: Antithyroid Agents; Calcimycin; Cell Count; Chemotaxis; Concanavalin A; Humans; Hydrogen Peroxide; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Propylthiouracil; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Regulation of protein phosphorylation in pancreatic acini. Distinct effects of Ca2+ ionophore A23187 and 12-O-tetradecanoylphorbol 13-acetate.
Topics: Amylases; Animals; Calcimycin; Carbachol; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Pancreas; Phorbols; Phosphorylation; Proteins; Species Specificity; Tetradecanoylphorbol Acetate | 1986 |
Increased prostaglandin synthesis by low calcium-regulated keratinocytes.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Epidermal Cells; Epidermis; Keratins; Prostaglandins; Tetradecanoylphorbol Acetate | 1986 |
Stimulatory and inhibitory effects of TMB-8 on pancreatic enzyme secretion.
Topics: Amylases; Animals; Calcimycin; Calcium; Carbachol; Dose-Response Relationship, Drug; Gallic Acid; L-Lactate Dehydrogenase; Pancreas; Rabbits; Sincalide; Tetradecanoylphorbol Acetate | 1986 |
Alpha-fetoprotein stimulates leukotriene synthesis in P388D1 macrophages.
Topics: alpha-Fetoproteins; Arachidonic Acids; Calcimycin; Interferon-gamma; Leukotriene B4; Lipopolysaccharides; Macrophage Activation; Macrophages; Prostaglandins; Silicon Dioxide; SRS-A; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Induction of c-fos and c-myc mRNA by epidermal growth factor or calcium ionophore is cAMP dependent.
Topics: 1-Methyl-3-isobutylxanthine; Blood Physiological Phenomena; Calcimycin; Calcium; Cholera Toxin; Cyclic AMP; Drug Synergism; Epidermal Growth Factor; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate | 1986 |
Oligodendrocyte adhesion activates protein kinase C-mediated phosphorylation of myelin basic protein.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Calcimycin; Cell Adhesion; Colforsin; Cyclic AMP; Enzyme Activation; Humans; Myelin Basic Protein; Neuroglia; Oligodendroglia; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Mechanisms subserving hormone action in the ovary: role of calcium ions as assessed by steady state calcium exchange in cultured swine granulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Dantrolene; Female; Granulosa Cells; In Vitro Techniques; Kinetics; Marine Toxins; Oxocins; Swine; Tetradecanoylphorbol Acetate; Trifluoperazine; Vanadates; Vanadium | 1987 |
Potentiation of PGE1-induced increase in cyclic AMP by chemotactic peptide and Ca2+ ionophore through calmodulin-dependent processes.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alprostadil; Animals; Calcimycin; Calmodulin; Colforsin; Cyclic AMP; Drug Synergism; Female; Guanosine Triphosphate; Guinea Pigs; Membrane Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandin Antagonists; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Effect of lysophosphatidylserine on immunological histamine release.
Topics: Animals; Antibodies, Anti-Idiotypic; Basophils; Calcimycin; Calcium; Histamine Release; Humans; Immunoglobulin E; Kinetics; Lysophospholipids; Male; Mast Cells; Nerve Growth Factors; Phosphatidylserines; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Stimulation of the phosphorylation of a 66,000-Da soluble tyrosine phosphoprotein by agents that activate or augment activation of human peripheral blood T lymphocytes.
Topics: Calcimycin; Dose-Response Relationship, Drug; Epidermal Growth Factor; Humans; Lymphocyte Activation; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine; Wheat Germ Agglutinins | 1987 |
The dual role of protein kinase C in the stimulus-secretion coupling of basophils.
Topics: Animals; Antigens; Basophils; Calcimycin; Calcium; Cytosol; Histamine Release; In Vitro Techniques; Leukemia, Experimental; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1985 |
Short-term cholinergic desensitization of rat pancreatic secretory response.
Topics: Amylases; Animals; Calcimycin; Calcium; Carbachol; Ceruletide; Dose-Response Relationship, Drug; In Vitro Techniques; N-Methylscopolamine; Pancreas; Pancreatic Juice; Rats; Scopolamine Derivatives; Secretory Rate; Tetradecanoylphorbol Acetate | 1987 |
Bombesin stimulation of gastrin release from canine gastrin cells in primary culture.
Topics: Adenylyl Cyclases; Animals; Bombesin; Calcimycin; Cells, Cultured; Colforsin; Dogs; Gastric Juice; Gastric Mucosa; Gastrins; Protein Kinase C; Receptors, Bombesin; Receptors, Neurotransmitter; Secretory Rate; Somatostatin; Substance P; Tetradecanoylphorbol Acetate | 1987 |
Synergism between thapsigargin and the phorbol ester 12-O-tetradecanoylphorbol 13-acetate on the release of [14C]arachidonic acid and histamine from rat peritoneal mast cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Carbon Radioisotopes; Drug Synergism; Histamine Release; In Vitro Techniques; Male; Mast Cells; Plant Extracts; Prostaglandin D2; Prostaglandins D; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thapsigargin | 1987 |
Demonstration of protein kinase C activity in crustacean Y-organs, and partial definition of its role in regulation of ecdysteroidogenesis.
Topics: Animals; Brachyura; Calcimycin; Calcium; Calmodulin; Cyclic AMP; Cycloheximide; Dactinomycin; Diglycerides; Ecdysteroids; In Vitro Techniques; Invertebrate Hormones; Neurosecretory Systems; Phospholipids; Protein Biosynthesis; Protein Kinase C; RNA; Tetradecanoylphorbol Acetate; Trifluoperazine | 1987 |
Effects of 1-oleoyl-2-acetyl glycerol are distinct from those of phorbol ester in rat pancreatic acini.
Topics: Amylases; Animals; Biological Transport; Calcimycin; Carbachol; Diglycerides; Enzyme Activation; ErbB Receptors; Glycerides; In Vitro Techniques; Male; Pancreas; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate | 1987 |
Specific inhibition of phorbol ester and DiC8-induced histamine release from human basophils by the protein kinase C inhibitors, H-7 and H-9.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Basophils; Calcimycin; Calmodulin; Diglycerides; Glycerides; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Isoquinolines; Kinetics; Perphenazine; Piperazines; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Release of arachidonic acid metabolites by human monocytes or lymphocytes: effect of treatment with interferon on stimulation by phorbol ester or calcium ionophore.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Drug Synergism; Humans; Hydroxyeicosatetraenoic Acids; Interferons; Leukotriene B4; Lymphocytes; Monocytes; Prostaglandins; Recombinant Proteins; SRS-A; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1987 |
Nicardipine-sensitive enhancement of high K+ -evoked dopamine release in PC12 cells pretreated with 12-O-tetradecanoylphorbol 13-acetate.
Topics: Adrenal Gland Neoplasms; Animals; Calcimycin; Calcium; Carbachol; Cell Line; Dopamine; Ion Channels; Nicardipine; Potassium; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1987 |
Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation.
Topics: Animals; Antigens; Calcimycin; Cell Line; Concanavalin A; Cyclosporins; Drug Synergism; Immunosuppressive Agents; Interleukin-2; Isoantigens; Lymphocyte Activation; Mice; Pyridines; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Tacrolimus; Tetradecanoylphorbol Acetate | 1987 |
Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Centrifugation, Density Gradient; Cytoplasmic Granules; Endopeptidases; Enzyme Activation; Exocytosis; Glucuronidase; Granzymes; Ion Channels; Isoflurophate; L-Lactate Dehydrogenase; Mice; Protein Kinase C; Receptors, Antigen, T-Cell; Serine Endopeptidases; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1987 |
Phorbol ester attenuates cholecystokinin-stimulated amylase release in pancreatic acini of rats.
Topics: Amylases; Animals; Calcimycin; Carbachol; Enzyme Activation; Kinetics; Male; Pancreas; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1987 |
Synergistic signals in the mechanism of antigen-induced exocytosis in 2H3 cells: evidence for an unidentified signal required for histamine release.
Topics: Antigens; Calcimycin; Calcium; Cells, Cultured; Exocytosis; Histamine Release; Kinetics; Ovalbumin; Tetradecanoylphorbol Acetate | 1987 |
Synergism between cellular messengers and agonist combinations in pepsinogen secretion.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bethanechol; Bethanechol Compounds; Bombesin; Calcimycin; Calcium; Cell Communication; Colforsin; Cyclic AMP; Drug Synergism; Esophagus; Fluorescent Antibody Technique; Isoproterenol; L-Lactate Dehydrogenase; Pepsinogens; Protein Kinase C; Rana catesbeiana; Tetradecanoylphorbol Acetate | 1987 |
Role of second messengers in regulating the growth-associated S6 protein kinase activity.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Avian Sarcoma Viruses; Bucladesine; Calcimycin; Cell Transformation, Neoplastic; Chick Embryo; Cyclic AMP; Fibroblasts; Inositol Phosphates; Kinetics; Phosphorylation; Protein Kinases; Proto-Oncogenes; Tetradecanoylphorbol Acetate | 1987 |
Studies on the calcium dependence of human NK cell killing.
Topics: Calcimycin; Calcium; Calcium Channel Blockers; Cytotoxicity, Immunologic; Humans; Ion Channels; Killer Cells, Natural; Membrane Potentials; Potassium; Sodium; Tetradecanoylphorbol Acetate; Tetrodotoxin; Veratridine | 1987 |
Distinct activation of Na+-H+ exchange by gastrin and CCK peptide in acini from guinea pig.
Topics: Amiloride; Amylases; Animals; Calcimycin; Calcium; Cholecystokinin; Diglycerides; Gastrins; Guinea Pigs; Hydrogen; Ion Exchange; Pancreas; Peptide Fragments; Peptides; Phorbol Esters; Secretin; Sodium; Tetradecanoylphorbol Acetate | 1988 |
Mechanism of adrenergic stimulation of anion secretion in cultured rat epididymal epithelium.
Topics: 1-Methyl-3-isobutylxanthine; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Bicarbonates; Bumetanide; Calcimycin; Calcium Channel Blockers; Cells, Cultured; Electric Conductivity; Epididymis; Epinephrine; Epithelium; Male; Rats; Rats, Inbred Strains; Sympathomimetics; Tetradecanoylphorbol Acetate | 1988 |
Effect of AA861, a 5-lipoxygenase inhibitor, on amylase secretion from rat pancreatic acini.
Topics: Amylases; Animals; Arachidonate Lipoxygenases; Benzoquinones; Bombesin; Calcimycin; Carbachol; Cholecystokinin; In Vitro Techniques; Indomethacin; Kinetics; Lipoxygenase Inhibitors; Male; Pancreas; Quinones; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Locus of inhibitory action of cAMP-dependent protein kinase in the antigen receptor-triggered cytotoxic T lymphocyte activation pathway.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Cholera Toxin; Colforsin; Cyclic AMP; Cytotoxicity, Immunologic; Exocytosis; Lymphocyte Activation; Protein Kinases; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1988 |
Effect of protein kinase C activation on mast cell histamine release.
Topics: Animals; Calcimycin; Cell Survival; Enzyme Activation; Glucose; Histamine Release; In Vitro Techniques; Kinetics; Male; Mast Cells; Potassium Cyanide; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Immature stimulus-secretion coupling in the developing exocrine pancreas and ontogenic changes of protein kinase C.
Topics: Amylases; Animals; Animals, Newborn; Bucladesine; Calcimycin; Cytosol; Fetus; Pancreas; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Secretory Rate; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Cyclic GMP inhibits protein kinase C-mediated secretion in rat pancreatic acini.
Topics: Amylases; Animals; Bethanechol; Bethanechol Compounds; Bombesin; Calcimycin; Calcium; Cyclic GMP; Dibutyryl Cyclic GMP; In Vitro Techniques; Kinetics; Pancreas; Pancreatic Juice; Protein Kinase C; Rats; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Control of bovine placental progesterone synthesis: roles of cholesterol availability and calcium-activated systems.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Cattle; Cholesterol; Drug Interactions; Female; Hydroxycholesterols; Placenta; Pregnancy; Progesterone; Tetradecanoylphorbol Acetate; Trifluoperazine | 1988 |
Downregulation of protein kinase C in guinea pig pancreatic acini: effects on secretion.
Topics: Amylases; Animals; Calcimycin; Carbachol; Guinea Pigs; Male; Osmolar Concentration; Pancreas; Protein Kinase C; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Differential expression of MHC class II antigens in chronic B-cell disorders.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antigens, Surface; B-Lymphocytes; Binding, Competitive; Calcimycin; Epitopes; Female; Histocompatibility Antigens Class II; Humans; Leukemia, Lymphoid; Major Histocompatibility Complex; Male; Middle Aged; Tetradecanoylphorbol Acetate | 1988 |
Early signals for keratinocyte differentiation: role of Ca2+-mediated inositol lipid metabolism in normal and neoplastic epidermal cells.
Topics: Animals; Calcimycin; Calcium; Cell Differentiation; Cells, Cultured; Choline; Epidermal Cells; Epidermis; Ethers; Inositol; Ionomycin; Keratins; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Histamine release from human basophils by synthetic block co-polymers composed of polyoxyethylene and polyoxypropylene and synergy with immunologic and non-immunologic stimuli.
Topics: Adjuvants, Immunologic; Adult; Antibodies, Anti-Idiotypic; Basophils; Calcimycin; Calcium; Concanavalin A; Dose-Response Relationship, Immunologic; Drug Synergism; Histamine Release; Humans; Immunoglobulin E; Poloxalene; Polyethylene Glycols; Tetradecanoylphorbol Acetate | 1988 |
Effects of a phorbol ester, a calcium ionophore, and 3',5'-adenosine monophosphate production on hen granulosa cell plasminogen activator activity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Chickens; Cyclic AMP; Cycloheximide; Dactinomycin; Female; Granulosa Cells; In Vitro Techniques; Isoquinolines; L-Lactate Dehydrogenase; Luteinizing Hormone; Piperazines; Plasminogen Activators; Progesterone; Protein Kinase C; Sheep; Tetradecanoylphorbol Acetate | 1988 |
The influence of tetradecanoyl-phorbol-acetate (TPA) on histamine release from isolated rat mast cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Diglycerides; Histamine Release; Isoquinolines; Male; Mast Cells; Piperazines; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Mode of inhibitory action of cholecystokinin in amylase release from isolated rat pancreatic acini--inhibition of secretory process post to protein kinase C-calcium ion systems.
Topics: Amylases; Animals; Calcimycin; Calcium; Drug Synergism; In Vitro Techniques; Male; Pancreas; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Inbred Strains; Sincalide; Tetradecanoylphorbol Acetate | 1988 |
Synergistic enhancement of histamine release from rat peritoneal mast cells by the phorbol ester 12-O-tetradecanoylphorbol 13-acetate is not reflected by corresponding changes in phospholipid turnover.
Topics: Animals; Antibodies, Anti-Idiotypic; Calcimycin; Drug Synergism; Histamine Release; Immunoglobulin E; Male; Mast Cells; Peritoneal Cavity; Phosphates; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylinositols; Phospholipids; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Interactions between phorbol esters and agents which increase cytosolic calcium in the guinea pig parenchymal strip: direct and indirect effects on the contractile response.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Cytosol; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Contraction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Vanadates | 1988 |
Stimulation of human amnion prostaglandin E2 production by activators of protein kinase-C.
Topics: Amnion; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Diglycerides; Dinoprostone; Drug Synergism; Enzyme Activation; Female; Humans; Pregnancy; Protein Biosynthesis; Protein Kinase C; RNA; Tetradecanoylphorbol Acetate | 1988 |
Effects of calcium ionophore and phorbol ester on class-II-restricted virus-specific human cytotoxic T cell clones.
Topics: Antigens, Viral; Calcimycin; Clone Cells; Cytotoxicity, Immunologic; Epitopes; HLA-D Antigens; Humans; Immunosuppressive Agents; Lymphocyte Activation; Measles virus; Phytohemagglutinins; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1988 |
Control of bovine placental progestin synthesis: calcium dependent steroidogenesis is modulated at the site of the cholesterol side chain cleavage enzyme.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Cyanoketone; Hydroxycholesterols; Placenta; Pregnenolone; Progesterone; Progestins; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1988 |
Cyclic GMP does not inhibit protein kinase C-mediated enzyme secretion in rat pancreatic acini.
Topics: Amylases; Animals; Bombesin; Calcimycin; Carbachol; Cyclic GMP; Dibutyryl Cyclic GMP; In Vitro Techniques; Kinetics; Male; Nitroprusside; Pancreas; Protein Kinases; Rats; Rats, Inbred Strains; Reference Values; Sincalide; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1989 |
Synergistic effect of palmitoylcarnitine and the ionophore A23187 on isolated rat mast cells.
Topics: Animals; Calcimycin; Carnitine; Drug Synergism; Histamine Release; Male; Mast Cells; Palmitoylcarnitine; Phloretin; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Inhibitory effect of phloretin on histamine release from isolated rat mast cells.
Topics: Animals; Calcimycin; Histamine Release; Male; Mast Cells; Phloretin; Quercetin; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Impermeant stilbene disulfonic acids block chemotactic peptide receptor function on human granulocytes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Calcimycin; Cell Aggregation; Granulocytes; Humans; In Vitro Techniques; Ion Channels; N-Formylmethionine Leucyl-Phenylalanine; Receptors, Formyl Peptide; Receptors, Immunologic; Stilbenes; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Calcium metabolism and bombesin-stimulated pancreatic enzyme secretion.
Topics: Amylases; Animals; Benzofurans; Bombesin; Calcimycin; Calcium; Fura-2; Guinea Pigs; In Vitro Techniques; Kinetics; Pancreas; Tetradecanoylphorbol Acetate | 1988 |
Beta-adrenergic and prostanoid inhibition of canine fundic mucosal mast cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Animals; Calcimycin; Colforsin; Concanavalin A; Cyclic AMP; Dinoprostone; Dogs; Enprostil; Epinephrine; Gastric Fundus; Gastric Mucosa; Histamine Release; Isoproterenol; Liver; Mast Cells; Propanolamines; Propranolol; Prostaglandins E, Synthetic; Tetradecanoylphorbol Acetate | 1989 |
Modulation of human leukocyte histamine release by sn-1,2-isopropylidene-3-decanoyl-glycerol and decanoic acid cyclopentyl methylester in comparison with effects of synthetic diacylglycerols and a phorbol ester.
Topics: Calcimycin; Cyclopentanes; Decanoic Acids; Diglycerides; Glyceryl Ethers; Histamine Release; Humans; Immunoglobulin E; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Triglycerides | 1989 |
Functional differences of human basophils with different densities.
Topics: Antibodies, Anti-Idiotypic; Basophils; Calcimycin; Centrifugation, Density Gradient; Histamine H1 Antagonists; Histamine Release; Humans; Immunoglobulin E; Leukocyte Count; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1989 |
Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140.
Topics: Antibodies, Monoclonal; Biological Transport; Calcimycin; Cell Membrane; Cytoplasmic Granules; Endothelium, Vascular; Fluorescent Antibody Technique; Histamine; Humans; Kinetics; P-Selectin; Platelet Membrane Glycoproteins; Tetradecanoylphorbol Acetate; Thrombin; Umbilical Veins; von Willebrand Factor | 1989 |
Differential expression of cytosolic activation factors for NADPH oxidase in HL-60 leukemic cells.
Topics: Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Cell Differentiation; Cell Line; Cytosol; Dimethyl Sulfoxide; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hexachlorocyclohexane; Humans; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Superoxides; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
Opposing effects of calcium entry and phorbol esters on fusion of chick muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium Channel Blockers; Cell Fusion; Cells, Cultured; Chick Embryo; Egtazic Acid; Gallopamil; Kinetics; Muscles; Myosin Subfragments; Myosin-Light-Chain Kinase; Myosins; Nitrendipine; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Tetradecanoylphorbol Acetate | 1989 |
4-Acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid inhibits adrenocorticotropin secretion from anterior pituitary cells.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Adrenocorticotropic Hormone; Animals; Calcimycin; Cell Line; Chloride Channels; Chlorides; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Female; Ion Channels; Kinetics; Membrane Proteins; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains; Stilbenes; Tetradecanoylphorbol Acetate | 1989 |
Specific effects of agonists of the calcium messenger system on secretion of 'late-pathway' steroid products by intact tissue and dispersed cells of the rat adrenal zona glomerulosa.
Topics: 18-Hydroxycorticosterone; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aldosterone; Animals; Calcimycin; Calcium; Cells, Cultured; Corticosterone; Dose-Response Relationship, Drug; Female; Male; Rats; Rats, Inbred Strains; Second Messenger Systems; Tetradecanoylphorbol Acetate; Zona Glomerulosa | 1989 |
The mechanism of action of the immunosuppressive drug FK-506.
Topics: Animals; Anti-Bacterial Agents; Calcimycin; Calcium; Cyclosporins; Immunosuppressive Agents; Lymphocyte Activation; Protein Kinase C; Swine; Tacrolimus; Tetradecanoylphorbol Acetate | 1989 |
Chloride secretory response of cystic fibrosis human airway epithelia. Preservation of calcium but not protein kinase C- and A-dependent mechanisms.
Topics: 1-Methyl-3-isobutylxanthine; Adolescent; Adult; Amiloride; Bradykinin; Calcimycin; Calcium; Child; Chlorides; Cyclic AMP; Cystic Fibrosis; Electric Conductivity; Epithelium; Female; Humans; Isoproterenol; Male; Nasal Mucosa; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Prostaglandin E analogue inhibition of pancreatic enzyme secretion.
Topics: 16,16-Dimethylprostaglandin E2; Amylases; Animals; Anti-Ulcer Agents; Calcimycin; Carbachol; Cholecystokinin; Diglycerides; Dose-Response Relationship, Drug; Female; Guinea Pigs; Pancreas; Prostaglandins E; Prostaglandins E, Synthetic; Rioprostil; Tetradecanoylphorbol Acetate | 1989 |
Phosphorylation of myosin light chain from adrenomedullary chromaffin cells in culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcimycin; Cattle; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Immunoenzyme Techniques; Kinetics; Molecular Weight; Myosin Subfragments; Phosphates; Phosphorylation; Potassium; Tetradecanoylphorbol Acetate; Trifluoperazine | 1989 |
Pituitary thyrotropin-releasing hormone (TRH) receptors: effects of TRH, drugs mimicking TRH action, and chlordiazepoxide.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcimycin; Cell Line; Chlordiazepoxide; Down-Regulation; Nimodipine; Pituitary Gland; Prolactin; Rats; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1989 |
Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers.
Topics: 1-Methyl-3-isobutylxanthine; Binding Sites; Blotting, Western; Calcimycin; Cell Differentiation; Colforsin; Cyclic AMP; DNA Probes; DNA-Binding Proteins; Gene Expression Regulation; Humans; Plasmids; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription Factor AP-2; Transcription Factors; Transcription, Genetic; Transfection; Tretinoin | 1989 |
Effect of age on brain cortical protein kinase C and its mediation of 5-hydroxytryptamine release.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Animals; Calcimycin; Calcium; Cerebral Cortex; Isoquinolines; Piperazines; Protein Kinase C; Rats; Rats, Inbred F344; Serotonin; Tetradecanoylphorbol Acetate | 1989 |
A role for protein kinase C-mediated phosphorylation in the mobilization of arachidonic acid in mouse macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Electrophoresis, Polyacrylamide Gel; Female; Lipopolysaccharides; Macrophages; Mice; Phosphoproteins; Protein Kinase C; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Choline-linked phosphoglycerides. A source of phosphatidic acid and diglycerides in stimulated neutrophils.
Topics: Calcimycin; Choline; Chromatography, High Pressure Liquid; Diglycerides; Glycerides; Glycerophosphates; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphatidic Acids; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Ligand-induced desensitization of 125I-epidermal growth factor internalization.
Topics: Animals; Calcimycin; Calmodulin; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Hydrogen-Ion Concentration; Iodine Radioisotopes; Mice; Peptide Hydrolases; Protein Kinase C; Streptomyces griseus; Tetradecanoylphorbol Acetate | 1989 |
Phorbol ester, 1,2-diacylglycerol, and collagen induce inhibition of arachidonic acid incorporation into phospholipids in human platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Acylglycerophosphocholine O-Acyltransferase; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Coenzyme A Ligases; Collagen; Diglycerides; Enzyme Activation; Glycerides; Isoquinolines; Phospholipids; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1989 |
Identification of tumor promoters by their inhibitory effect on intercellular transfer of lucifer yellow.
Topics: Animals; Anthralin; Butylated Hydroxytoluene; Calcimycin; Carcinogens; Cells, Cultured; Cricetinae; DDT; Diterpenes; Fluorescent Dyes; Intercellular Junctions; Isoquinolines; Lyngbya Toxins; Phenobarbital; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Stimulation of AIDS lymphocytes with calcium ionophore (A23187) and phorbol ester (PMA): studies of cytoplasmic free Ca, IL-2 receptor expression, IL-2 production, and proliferation.
Topics: Acquired Immunodeficiency Syndrome; Calcimycin; Calcium; Cytoplasm; Humans; Interleukin-2; Lymphocyte Activation; Lymphocytes; Male; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate | 1989 |
Activators of protein kinase C trigger cortical granule exocytosis, cortical contraction, and cleavage furrow formation in Xenopus laevis oocytes and eggs.
Topics: Animals; Calcimycin; Calcium; Diglycerides; Enzyme Activation; Exocytosis; Oocytes; Ovum; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Tretinoin; Xenopus laevis | 1989 |
Tumor promoter 12-0-tetradecanoyl-phorbol-13-acetate (TPA) can reduce the Ca-transporting ability of Ca-ionophores in T lymphocytes: the involvement of intracellular heavy metal ions.
Topics: Animals; Biological Transport; Calcimycin; Calcium; Ethers; Ethylenediamines; Extracellular Space; Fluorescence Polarization; Ionomycin; Ionophores; Metals; Mice; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Generation of hydrogen peroxide in cultured porcine thyroid cells: synergistic regulation by cytoplasmic free calcium and protein kinase C.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Cytoplasm; Drug Synergism; Hydrogen Peroxide; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyroid Gland | 1989 |
Expression of interleukin 2 and the interleukin 2 receptor in aging rats.
Topics: Aging; Animals; Blotting, Northern; Calcimycin; Cells, Cultured; Concanavalin A; Gene Expression Regulation; Interleukin-2; Lymphocyte Activation; Rats; Rats, Inbred F344; Receptors, Interleukin-2; RNA, Messenger; Spleen; Tetradecanoylphorbol Acetate | 1989 |
Functional properties of intra-epithelial lymphocytes from mouse small intestine. IV. Investigation of the proliferative capacity of IEL using phorbol ester and calcium ionophore.
Topics: Animals; Calcimycin; Cells, Cultured; Epithelium; Female; Interleukin-2; Intestine, Small; Lymphocyte Activation; Male; Mice; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Ability of prostaglandin to reduce ethanol injury to dispersed chief cells from guinea pig stomach.
Topics: 16,16-Dimethylprostaglandin E2; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Carbachol; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane Permeability; Colforsin; Ethanol; Female; Gastric Mucosa; Guinea Pigs; L-Lactate Dehydrogenase; Microscopy, Electron; Microscopy, Electron, Scanning; Pepsinogens; Prostaglandins E, Synthetic; Rosaniline Dyes; Sincalide; Tetradecanoylphorbol Acetate | 1989 |
Ca2+-dependent and -independent secretagogue action on gastric mucus secretion in rabbit mucosal explants.
Topics: Acetylcholine; Acetylglucosamine; Animals; Atropine; Calcimycin; Calcium; Calmodulin; Colforsin; Dinoprostone; Gastric Fundus; Gastric Mucosa; Glycoproteins; Histamine; Male; Molecular Weight; Organ Culture Techniques; Pentagastrin; Pyloric Antrum; Rabbits; Sulfonamides; Tetradecanoylphorbol Acetate | 1989 |
Phorbol diester enhances calcium ionophore A23187-induced [3H]acetate incorporation into platelet-activating factor in murine macrophages: predominant incorporation into 1-O-acyl-2-acetyl-sn-glycero-3-phosphocholine.
Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Macrophages; Mice; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Cyclosporin A-mediated inhibition of mitogen-induced gene transcription is specific for the mitogenic stimulus and cell type.
Topics: Calcimycin; Cell Line; Cyclosporins; Fibroblasts; Gene Expression Regulation; Humans; Lymphocyte Activation; Mitogens; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation | 1989 |
Mechanism of T cell proliferation in vivo: analysis of IL-2 receptor expression and activation of c-myc and c-myb oncogenes during lymphatic regeneration.
Topics: Animals; Calcimycin; Cell Division; Concanavalin A; Cyclophosphamide; Gene Expression Regulation; Lymphatic System; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myb; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; Receptors, Interleukin-2; Regeneration; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Modulation by phorbol 12-myristate 13-acetate of arachidonic acid release from rat basophilic leukemia cells stimulated with A23187.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Drug Synergism; Leukemia, Basophilic, Acute; Phospholipases; Phospholipids; Prostaglandin D2; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Rapid expression of protooncogenes c-fos and c-myc in B-chronic lymphocytic leukemia cells during differentiation induced by phorbol ester and calcium ionophore.
Topics: Blotting, Northern; Calcimycin; Cell Differentiation; Cell Division; DNA; Drug Synergism; Gene Expression Regulation; Humans; Immunoglobulin M; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Possible involvement of Ca2+ mobilization and protein kinase C activation in the induction of spontaneous metastasis by mouse mammary adenocarcinoma cells.
Topics: Animals; Calcimycin; Calcium; DNA; Enzyme Activation; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Neoplasm Metastasis; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Evidence that rat Kupffer cells stimulate and inhibit hepatocyte protein synthesis in vitro by different mechanisms.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Calcimycin; Cells, Cultured; Dexamethasone; Escherichia coli; Kupffer Cells; Leucine; Lipopolysaccharides; Liver; Male; Protein Biosynthesis; Rats; Rats, Inbred Lew; Tetradecanoylphorbol Acetate | 1989 |
Recombinant hematopoietic growth factors fail to induce a proliferative response in precursor B acute lymphoblastic leukemia.
Topics: B-Lymphocytes; Calcimycin; Cell Division; Colony-Stimulating Factors; Humans; Interleukin-4; Interleukins; Leukemia, Lymphoid; Neoplastic Stem Cells; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1989 |
Cholecystokinin-induced desensitization of pepsinogen secretion from chief cells.
Topics: Animals; Calcimycin; Calcium; Female; Gastric Mucosa; Guinea Pigs; Pepsinogens; Receptors, Cholecystokinin; Sincalide; Temperature; Tetradecanoylphorbol Acetate | 1989 |
Regulation of phospholipase D in HL-60 granulocytes. Activation by phorbol esters, diglyceride, and calcium ionophore via protein kinase- independent mechanisms.
Topics: Calcimycin; Cell Line; Diglycerides; Enzyme Activation; Glycerides; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Phorbol 12,13-Dibutyrate; Phospholipase D; Phospholipases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Changes in inducibility of IL-2 receptor alpha-chain and T cell-receptor expression during thymocyte differentiation in the mouse.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Cell Differentiation; Cell Survival; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phenotype; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Possible involvement of microfilaments in protein kinase C translocation.
Topics: Actin Cytoskeleton; Animals; Azepines; Biological Transport; Calcimycin; Calmodulin; Cytochalasin B; Cytoskeleton; Cytosol; Female; Male; Mice; Mice, Inbred C57BL; Myosin-Light-Chain Kinase; Neutrophils; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate | 1989 |
Cellular activation without proliferation to B cell growth factor and interleukin 2 in chronic lymphocytic leukaemia B cells stimulated with phorbol ester plus calcium ionophore.
Topics: B-Lymphocytes; Calcimycin; Cell Extracts; Cells, Cultured; Humans; Interleukin-2; Interleukin-4; Interleukins; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Tetradecanoylphorbol Acetate | 1989 |
Dynamics of the diradylglycerol responses of stimulated phagocytes.
Topics: Calcimycin; Calcium; Cytochalasin B; Diglycerides; Gas Chromatography-Mass Spectrometry; Glycerides; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phagocytes; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Regulation of levels of IL-1 mRNA in human fibroblasts.
Topics: Calcimycin; Cell Line; Cycloheximide; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1; Kinetics; Methionine; Ouabain; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1989 |
Increased phagocytic cell chemiluminescence in patients with cystic fibrosis.
Topics: Adolescent; Adult; Calcimycin; Child; Cystic Fibrosis; Humans; Luminescent Measurements; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Agonist-dependent generation of lipoxins from rat basophilic leukemia cell (RBL-1).
Topics: Animals; Calcimycin; Hydroxyeicosatetraenoic Acids; Leukotrienes; Lipid Peroxides; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Differential responsiveness of human B lymphocytes to phorbol ester and calcium ionophore based on their state of activation.
Topics: B-Lymphocytes; Calcimycin; Cells, Cultured; DNA; Humans; Lymphocyte Activation; Palatine Tonsil; Tetradecanoylphorbol Acetate | 1989 |
Stimulus-specific production of cyclooxygenase and lipoxygenase metabolites of arachidonic acid by bovine alveolar macrophages.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Cattle; Cells, Cultured; Macrophages; Male; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Cell Nucleus; Cells, Cultured; Cytosol; DNA; Isoquinolines; Kinetics; Male; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thymus Gland | 1989 |
Analysis of site of action of a choriocarcinoma-derived immunoregulatory factor on IL-2-mediated T cell responses.
Topics: Calcimycin; Cell Differentiation; Cell Division; Choriocarcinoma; Concanavalin A; Humans; Immune Tolerance; Interleukin-2; Receptors, Interleukin-2; Recombinant Proteins; Suppressor Factors, Immunologic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Trophoblasts; Tumor Cells, Cultured | 1989 |
Synergistic stimulation of prostaglandin E2 production by calcium ionophore and protein kinase C activator in rat granulosa cells.
Topics: Animals; Calcimycin; Cholera Toxin; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Granulosa Cells; Melitten; Progesterone; Rats; Rats, Inbred Strains; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
Regulation of dog urothelial cell arachidonic acid release and prostaglandin E2 synthesis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cell Division; Cells, Cultured; Culture Media; Cycloheximide; Dinoprostone; Dogs; Epithelium; Kinetics; Microscopy, Electron; Tetradecanoylphorbol Acetate; Urinary Bladder | 1989 |
Defective protein phosphorylation associated with hypofunctions in stroke-prone spontaneously hypertensive rat platelets.
Topics: Animals; Blood Platelets; Blood Pressure; Blood Proteins; Calcimycin; Calcium; Cerebrovascular Disorders; Diglycerides; Disease Susceptibility; Hypertension; Phosphatidic Acids; Phospholipids; Phosphorylation; Platelet Aggregation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Tannin mediated alveolar macrophage protein phosphorylation.
Topics: Animals; Autoradiography; Calcimycin; Densitometry; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Macrophages; Phosphorylation; Proteins; Pulmonary Alveoli; Rabbits; Tannins; Tetradecanoylphorbol Acetate | 1989 |
Effects of TPA, A23187, and prostaglandin F2 alpha on progesterone synthesis by dispersed ovine luteal cells.
Topics: Animals; Calcimycin; Cells, Cultured; Corpus Luteum; Dinoprost; Female; Indomethacin; Progesterone; Sheep; Tetradecanoylphorbol Acetate | 1989 |
Enhancement of arachidonic acid liberation by protein kinase C activator is partially dependent on extracellular Na+ in rabbit platelets.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Diglycerides; Drug Synergism; Enzyme Activation; Guanosine Triphosphate; Hydrogen-Ion Concentration; Intracellular Membranes; Protein Kinase C; Rabbits; Sodium; Tetradecanoylphorbol Acetate | 1989 |
Activation of a suicide process of thymocytes through DNA fragmentation by calcium ionophores and phorbol esters.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Cell Survival; Cycloheximide; Dactinomycin; DNA Damage; Isoquinolines; Lectins; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Peanut Agglutinin; Phenotype; Piperazines; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Phospholipase activation and arachidonic acid release in cultured intestinal epithelial cells (INT 407).
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Diglycerides; Enzyme Activation; Epithelial Cells; Epithelium; Humans; Intestinal Mucosa; Phospholipases; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1989 |
Differential lymphocyte growth-modifying effects of oxidants: changes in cytosolic Ca+2.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Chelating Agents; Concanavalin A; Cytosol; Egtazic Acid; Female; Hydrogen Peroxide; Mice; Mice, Inbred CBA; Oxidation-Reduction; Sulfhydryl Compounds; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Hydrocortisone treatment increases the sensitivity and responsiveness to cholecystokinin in rat pancreas.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bombesin; Calcimycin; Calcium; Carbachol; Cell Separation; Cholecystokinin; Dose-Response Relationship, Drug; Hydrocortisone; Male; Pancreas; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Secretin; Secretory Rate; Tetradecanoylphorbol Acetate | 1989 |
Bryostatin 1 induces differentiation of B-chronic lymphocytic leukemia cells.
Topics: Aged; Antineoplastic Agents; B-Lymphocytes; Biomarkers, Tumor; Bryostatins; Calcimycin; Cell Adhesion; Cell Aggregation; Cell Differentiation; DNA, Neoplasm; Female; Humans; Immunoglobulins; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Male; Middle Aged; Receptors, Antigen, B-Cell; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Interleukin 2, interleukin 2 receptor, and interferon-gamma synthesis and mRNA expression in phorbol myristate acetate and calcium ionophore A23187-stimulated T cells from elderly humans.
Topics: Adult; Aged; Aging; Calcimycin; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Modulation of calcium-induced eicosanoid synthesis in mouse peritoneal macrophages by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Dinoprostone; Fatty Acids, Unsaturated; In Vitro Techniques; Isoquinolines; Macrophages; Mice; Mice, Inbred DBA; Piperazines; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1989 |
The lipoxygenase pathway and chemiluminescence in horse eosinophilic leukocytes.
Topics: Animals; Calcimycin; Eosinophils; Horses; In Vitro Techniques; Leukotrienes; Lipoxygenase; Luminescent Measurements; Luminol; Tetradecanoylphorbol Acetate | 1989 |
Phorbol esters induce retrograde myoelectric activity in rabbit ileum in vivo.
Topics: Animals; Calcimycin; Diglycerides; Electric Conductivity; Electrophysiology; Ileum; Indomethacin; Male; Muscle, Smooth; Phorbol Esters; Rabbits; Tetradecanoylphorbol Acetate | 1989 |
Exocytotic enzyme release from rabbit polymorphonuclear leukocytes after treatment with fluoride and calcium.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Calcium Radioisotopes; Exocytosis; Glyceric Acids; Glycogen; Glycolysis; L-Lactate Dehydrogenase; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1989 |
Cell-membrane phospholipase C is involved in inducing the antiviral effect of interferon.
Topics: Antibodies; Calcimycin; Cell Line; Cell Membrane; Humans; Interferon Type I; Tetradecanoylphorbol Acetate; Type C Phospholipases; Viral Interference; Virus Replication | 1989 |
Characterization of the hydroperoxide response observed in mouse skin treated with tumor promoters in vivo.
Topics: Animals; Calcimycin; Carcinogens; Dose-Response Relationship, Drug; Female; Hydrogen Peroxide; Ionomycin; Kinetics; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Reference Values; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Involvement of protein kinase C in translocation of desmoplakins from cytosol to plasma membrane during desmosome formation in human squamous cell carcinoma cells grown in low to normal calcium concentration.
Topics: Calcimycin; Calcium; Carcinoma, Squamous Cell; Cell Membrane; Cytoskeletal Proteins; Cytosol; Desmoplakins; Desmosomes; Diglycerides; Dose-Response Relationship, Drug; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Inositol lipids and LHRH action in the rat ovary.
Topics: Animals; Calcimycin; Calcium; Female; Gonadotropin-Releasing Hormone; Inositol; Ovary; Progesterone; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1989 |
Immunodeficiency after allogeneic bone marrow transplantation in man. Effect of phorbol ester (phorbol myristate acetate) and calcium ionophore (A23187) in vitro.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Calcimycin; Calcium; Cells, Cultured; Child; Female; Humans; Immunologic Deficiency Syndromes; Interleukin-2; Lymphocyte Activation; Male; Phytohemagglutinins; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Demonstration of functional immaturity of signal transduction pathways in human cord T cells.
Topics: Adult; Calcimycin; Concanavalin A; Fetal Blood; HLA-DR Antigens; Humans; In Vitro Techniques; Infant, Newborn; Interleukin-2; Lymphocyte Activation; Receptors, Interleukin-2; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Epidermal growth factor modulates release of arachidonic acid from embryonic cells.
Topics: Animals; Arachidonic Acids; Calcimycin; Cells, Cultured; Embryo, Mammalian; Enzyme Activation; Epidermal Growth Factor; Gestational Age; Kinetics; Mice; Mice, Inbred C57BL; Models, Biological; Phospholipases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Canine enteric submucosal cultures: transmitter release from neurotensin-immunoreactive neurons.
Topics: Animals; Calcimycin; Cells, Cultured; Colforsin; Dogs; Ileum; Immunohistochemistry; Intestinal Mucosa; Neurotensin; Tetradecanoylphorbol Acetate | 1989 |
The receptors for ATP and fMetLeuPhe are independently coupled to phospholipases C and A2 via G-protein(s). Relationship between phospholipase C and A2 activation and exocytosis in HL60 cells and human neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Enzyme Activation; Glucuronidase; GTP-Binding Proteins; Humans; Inositol Phosphates; Neutrophils; Pertussis Toxin; Phospholipases; Phospholipases A; Phospholipases A2; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Purinergic; Ribonucleotides; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1989 |
Augmented production of platelet-activating factor in human polymorphonuclear leukocytes by ketone bodies.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Calcimycin; Dimethyl Sulfoxide; Humans; Hydroxybutyrates; In Vitro Techniques; Kinetics; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Hormonal stimulation of diacylglycerol formation in hepatocytes. Evidence for phosphatidylcholine breakdown.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Angiotensin II; Animals; Arginine Vasopressin; Calcimycin; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diglycerides; Egtazic Acid; Epinephrine; Fatty Acids; Glucagon; Glycerides; Hormones; Kinetics; Liver; Male; Phosphatidylcholines; Phospholipids; Rats; Tetradecanoylphorbol Acetate | 1989 |
Thrombin causes increased monocytic-cell adhesion to endothelial cells through a protein kinase C-dependent pathway.
Topics: Animals; Aspirin; Calcimycin; Cattle; Cell Adhesion; Endothelium, Vascular; Heparin; Humans; In Vitro Techniques; Monocytes; Platelet Activating Factor; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Extracellular ATP stimulates poly(inositol phospholipid) hydrolysis and eicosanoid synthesis in mouse peritoneal macrophages in culture.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Cells, Cultured; Dinoprostone; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Macrophages; Mice; Mice, Inbred Strains; Peritoneal Cavity; SRS-A; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1989 |
Induction of c-fos mRNA in rat lymphoma Nb-2 cells.
Topics: Animals; Calcimycin; Cyclosporins; Enzyme Activation; Gene Expression; Lymphoma; Melitten; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1989 |
Modulation of arterial endothelial permeability: studies on an in vitro model.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Albumins; Animals; Aorta, Thoracic; Arteries; Bradykinin; Calcimycin; Catalase; Endothelium, Vascular; Histamine; In Vitro Techniques; Muscle, Smooth, Vascular; Permeability; Platelet Activating Factor; Superoxide Dismutase; Swine; Tetradecanoylphorbol Acetate | 1989 |
Ca2+ transients and Mn2+ entry in human neutrophils induced by thapsigargin.
Topics: Benzofurans; Calcimycin; Calcium; Computer Simulation; Erythrocytes; Fluorescent Dyes; Fura-2; Homeostasis; Humans; Manganese; Mathematics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Plant Extracts; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1989 |
Aromatic tetra-amidines with antiproteolytic activity inhibit platelet aggregation and secretion.
Topics: Adenosine Diphosphate; Amidines; Benzamidines; Blood Platelets; Calcimycin; Collagen; Depression, Chemical; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Ristocetin; Secretory Rate; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Acetyltransferase activity and production of platelet-activating factor by human neutrophils activated with various stimuli.
Topics: Acetyltransferases; Calcimycin; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Endothelial inositol phosphate generation and prostacyclin production in response to G-protein activation by AlF4-.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 6-Ketoprostaglandin F1 alpha; Aluminum; Aluminum Compounds; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Epoprostenol; Female; Fluorides; Fluorine; GTP-Binding Proteins; Humans; Inositol Phosphates; Isoquinolines; Kinetics; Pertussis Toxin; Piperazines; Pregnancy; Protein Kinase C; Signal Transduction; Sodium Fluoride; Tetradecanoylphorbol Acetate; Umbilical Veins; Virulence Factors, Bordetella | 1989 |
Regulation of muscle AChR alpha subunit gene expression by electrical activity: involvement of protein kinase C and Ca2+.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Chick Embryo; Dantrolene; Gene Expression Regulation; Macromolecular Substances; Muscles; Protein Kinase C; Receptors, Cholinergic; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetrodotoxin; Transcription, Genetic; Verapamil | 1989 |
In vitro proliferation of murine spleen cells: genetic control of proliferative responses induced by phorbol ester and calcium ionophore A23187.
Topics: Animals; B-Lymphocytes; Calcimycin; Cell Division; Cells, Cultured; Crosses, Genetic; Female; Gene Expression Regulation; Interleukin-2; Kinetics; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Receptors, Interleukin-2; Recombinant Proteins; Species Specificity; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Impaired T-cell activation in patients with systemic lupus erythematosus.
Topics: Adult; Calcimycin; Calcium; Cell Separation; Cells, Cultured; Female; Humans; Interleukin-2; Lupus Erythematosus, Systemic; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Protein kinase C-dependent and -independent mechanisms of cloned murine T cell proliferation. The role of protein kinase C translocation and protein kinase C activity.
Topics: Animals; Calcimycin; Clone Cells; Diglycerides; Dose-Response Relationship, Immunologic; Drug Combinations; Enzyme Activation; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Effect of ANP on sustained aldosterone secretion stimulated by angiotensin II.
Topics: Aequorin; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcimycin; Calcium; Cattle; Cell Membrane; Diglycerides; Luminescent Measurements; Peptide Fragments; Phosphoproteins; Phosphorylation; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate; Zona Glomerulosa | 1989 |
Induction of T cell function via the gp33/27 activation inducer molecule (AIM) requires co-expression of the CD3/TcR complex.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Humans; Lectins, C-Type; Lymphocyte Activation; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Formation of lipoxins by rat basophilic leukemia cells.
Topics: Animals; Calcimycin; Cell Line; Hydroxyeicosatetraenoic Acids; Leukemia, Basophilic, Acute; Leukotrienes; Lipid Peroxides; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Rats; Tetradecanoylphorbol Acetate | 1989 |
Enzyme immunoassay of thromboxane B2 using immobilized hapten and enzyme amplification.
Topics: Blood Platelets; Calcimycin; Haptens; Humans; Immunoenzyme Techniques; Radioimmunoassay; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1989 |
Expression and regulation of interleukin-1 mRNA and interleukin-1 receptors in human B-cell lines.
Topics: B-Lymphocytes; Blotting, Northern; Calcimycin; Cell Line; Cells, Cultured; Cycloheximide; Dexamethasone; Humans; Interleukin-1; Receptors, Immunologic; Receptors, Interleukin-1; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
EGF induces differentiation of an IL-3-dependent cell line expressing the EGF receptor.
Topics: Animals; Calcimycin; Cell Differentiation; Cell Division; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Interleukin-3; Mast Cells; Mice; Oncogene Proteins; Phosphorylation; Tetradecanoylphorbol Acetate; Tyrosine | 1989 |
Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression.
Topics: Amino Acid Sequence; Base Sequence; Bovine papillomavirus 1; Calcimycin; Chromosomes, Human, Pair 5; Clone Cells; Cloning, Molecular; DNA-Binding Proteins; Gene Expression Regulation; Genes; Human T-lymphotropic virus 1; Humans; Interleukin-4; Interleukins; Lymphocyte Activation; Molecular Sequence Data; Retroviridae Proteins; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transfection; Viral Proteins | 1989 |
Effect of iodide on glucose oxidation and 32P incorporation into phospholipids stimulated by different agents in dog thyroid slices.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Carbachol; Carbon Dioxide; Cholera Toxin; Dogs; Glucose; Iodides; Methylene Blue; Oxidation-Reduction; Phospholipids; Phosphorus Radioisotopes; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin | 1989 |
Interleukin 3-stimulated proliferation is sensitive to pertussis toxin: evidence for a guanyl nucleotide regulatory protein-mediated signal transduction mechanism.
Topics: Animals; Bucladesine; Calcimycin; Cell Division; Cell Line; Cholera Toxin; GTP-Binding Proteins; Interleukin-3; Mice; Monosaccharide Transport Proteins; Pertussis Toxin; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
Bacterial lipopolysaccharides prime human neutrophils for enhanced production of leukotriene B4.
Topics: Calcimycin; Calcium; Cytosol; Humans; Kinetics; Leukotriene B4; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Oxidation-Reduction; Salmonella; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Interleukin-2 suppression in cats naturally infected with feline leukemia virus.
Topics: Animals; Biological Assay; Calcimycin; Cats; Concanavalin A; Immune Tolerance; Interleukin-2; Kinetics; Leukemia Virus, Feline; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1989 |
Virus-induced enhancement of arachidonate metabolism by bovine alveolar macrophages in vitro.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cattle; Macrophages; Male; Parainfluenza Virus 3, Human; Paramyxoviridae Infections; Phospholipids; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Tritium; Zymosan | 1989 |
Erythromycin and roxithromycin potentiate human neutrophil locomotion in vitro by inhibition of leukoattractant-activated superoxide generation and autooxidation.
Topics: Calcimycin; Cell Movement; Erythromycin; Humans; In Vitro Techniques; Leucomycins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Propionates; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Responses of neutrophilic granulocytes in vitro of asthmatic and healthy subjects and the degree of inhibition by several drugs.
Topics: Adolescent; Albuterol; Asthma; Calcimycin; Child; Child, Preschool; Cromolyn Sodium; Enzyme Inhibitors; Granulocytes; Humans; Imidazoles; In Vitro Techniques; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Biochemical characterization of the inhibitory effect of CsA on cytolytic T lymphocyte effector functions.
Topics: Animals; Calcimycin; Calmodulin-Binding Proteins; Cyclosporins; Cytoplasmic Granules; Cytotoxicity, Immunologic; Exocytosis; Mast Cells; Mice; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1989 |
Possible roles of cAMP and Ca2+ in the regulation of miracidial transformation in Schistosoma mansoni.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Cholera Toxin; Colforsin; Cyclic AMP; Gallic Acid; Imidazoles; Nicardipine; Quaternary Ammonium Compounds; Schistosoma mansoni; Serotonin; Sodium Chloride; Sulfonamides; Tetradecanoylphorbol Acetate | 1989 |
Effects of luminal Na+ on single Na+ channels in A6 cells, a regulatory role for protein kinase C.
Topics: Amiloride; Animals; Calcimycin; Cell Line; Diglycerides; Electric Conductivity; Homeostasis; Kidney; Kinetics; Protein Kinase C; Sodium; Sodium Channels; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
Forskolin stimulates pinealocyte cGMP accumulation. Dramatic potentiation by an alpha 1-adrenergic----[Ca2+]i mechanism involving protein kinase C.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcium; Cations, Divalent; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Female; Phenylephrine; Pineal Gland; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate | 1989 |
Rapid modulation of rat adipocyte lipoprotein lipase: effect of calcium, A23187 ionophore, and thrombin.
Topics: Adipose Tissue; Animals; Calcimycin; Calcium; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Insulin; Lipid Metabolism; Lipoprotein Lipase; Microbial Collagenase; Rats; Tetradecanoylphorbol Acetate; Thrombin; Trypsin | 1989 |
Temporal integration of alpha 1-adrenergic responses in BC3H-1 muscle cells. Regulation of glycogen phosphorylase activity.
Topics: Calcimycin; Calcium; Cell Line; Diglycerides; Enzyme Activation; Kinetics; Muscles; Phosphorylases; Protein Kinase C; Receptors, Adrenergic, alpha; Receptors, Histamine; Tetradecanoylphorbol Acetate | 1989 |
Inhibitory effect of antibiotic cerulenin on the respiratory burst in phagocytes. II. Inhibition by cerulenin of intracellular calcium mobilization in human neutrophils.
Topics: Antifungal Agents; Bacterial Toxins; Calcimycin; Calcium; Cerulenin; Diglycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Phagocytes; Phagocytosis; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Phospholipase A2-mediated release of arachidonic acid in stimulated guinea pig alveolar macrophages: interaction with lipid mediators and cyclic AMP.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Cyclic AMP; Dinoprostone; Guinea Pigs; Lipid Metabolism; Lipids; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1989 |
Occult intracellular calcium pools: relevance to neutrophil oxidant production.
Topics: Calcimycin; Calcium; Cytosol; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Verapamil | 1989 |
Modulatory activity of 9-hydroxy- and 9-hydroperoxy-octadecadienoic acid towards reactive oxygen species from guinea-pig pulmonary macrophages.
Topics: Animals; Calcimycin; Cell Aggregation; Escherichia coli; Fatty Acids, Unsaturated; Guinea Pigs; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Linoleic Acids; Linoleic Acids, Conjugated; Luminescent Measurements; Macrophages; Male; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase; Zymosan | 1989 |
Leukotriene B4 metabolism in neutrophils of patients with chronic granulomatous disease: phorbol myristate acetate decreases endogenous leukotriene B4 via NADPH oxidase-dependent mechanism.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Granulomatous Disease, Chronic; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Male; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; SRS-A; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Cytoplasmic pH dependency of Na+/H+ exchange in human platelets activated with thrombin, arachidonic acid, A23187 and TPA.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Carrier Proteins; Cytoplasm; Humans; Hydrogen; Hydrogen-Ion Concentration; Nigericin; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Studies of protein kinase C in the rat basophilic leukemia (RBL-2H3) cell reveal that antigen-induced signals are not mimicked by the actions of phorbol myristate acetate and Ca2+ ionophore.
Topics: Alkaloids; Animals; Antigens; Basophils; Calcimycin; Cell Line; Enzyme Activation; Kinetics; Leukemia; Phosphatidylinositols; Protein Kinase C; Rats; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1989 |
Chondrocyte activation by interleukin-1: synergism with fibroblast growth factor and phorbol myristate acetate.
Topics: Animals; Calcimycin; Cartilage, Articular; DNA Probes; Fibroblast Growth Factors; Interleukin-1; Microbial Collagenase; Rabbits; RNA, Messenger; Tetradecanoylphorbol Acetate | 1989 |
Chondrocyte activation by interleukin-1: analysis of the synergistic properties of fibroblast growth factor and phorbol myristate acetate.
Topics: Animals; Calcimycin; Cartilage, Articular; Dinoprostone; DNA Probes; Drug Synergism; Fibroblast Growth Factors; Gelatinases; Interleukin-1; Metalloendopeptidases; Microbial Collagenase; Pepsin A; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
A role for protein kinase C in the membrane fusion necessary for platelet granule secretion.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Blood Platelets; Calcimycin; Carrier Proteins; Cytoplasmic Granules; Diglycerides; Humans; In Vitro Techniques; Isoquinolines; Membrane Fusion; Membrane Potentials; Phosphoproteins; Piperazines; Platelet Aggregation; Protein Kinase C; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
In vivo and in vitro HeNe laser effects on phagocyte functions.
Topics: Adenosine Triphosphate; Antigens, Differentiation; Calcimycin; Cell Movement; Helium; Humans; Lasers; Macrophage-1 Antigen; Neon; Neutrophils; Phytohemagglutinins; Receptors, Leukocyte-Adhesion; Skin Window Technique; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Synergistic release of arachidonic acid from platelets by activators of protein kinase C and Ca2+ ionophores. Evidence for the role of protein phosphorylation in the activation of phospholipase A2 and independence from the Na+/H+ exchanger.
Topics: Adenosine Triphosphate; Alkaloids; Amiloride; Arachidonic Acids; Aspirin; Blood Platelets; Calcimycin; Carrier Proteins; Enzyme Activation; Humans; Indoles; Ionomycin; Ionophores; Kinetics; Lactams; Phospholipases; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Sodium-Hydrogen Exchangers; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1989 |
Cyclic AMP inhibits chemotactic-peptide-induced but not Ca2+-ionophore- or tetradecanoylphorbol-acetate-induced enzyme secretion in guinea pig neutrophils.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Bucladesine; Calcimycin; Cyclic AMP; Guinea Pigs; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
Effect of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TTPA) upon membrane ionic exchanges in sea urchin eggs.
Topics: Amiloride; Animals; Biological Transport, Active; Calcimycin; Carrier Proteins; Cell Membrane; Female; Hydrogen-Ion Concentration; Kinetics; Male; Ouabain; Ovum; Rubidium; Sea Urchins; Signal Transduction; Sodium; Sodium-Hydrogen Exchangers; Sperm-Ovum Interactions; Tetradecanoylphorbol Acetate; Zygote | 1989 |
PDGF and intracellular signaling in the timing of oligodendrocyte differentiation.
Topics: Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Calcimycin; Calcium; Cell Differentiation; Cells, Cultured; Cyclic AMP; DNA; Humans; Mitosis; Oligodendroglia; Optic Nerve; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate | 1989 |
Comparative effects of F1 and P1 fractions obtained from a Klebsiella pneumoniae glycoproteic extract (RU 41740) on polymorphonuclear leukocytes.
Topics: Adjuvants, Immunologic; Bacterial Proteins; Calcimycin; Chemical Fractionation; Glucuronidase; Humans; Klebsiella pneumoniae; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways.
Topics: Animals; Base Sequence; Biological Factors; Blotting, Northern; Bucladesine; Calcimycin; Cell Line; Colforsin; Cytokines; DNA-Binding Proteins; DNA-Directed DNA Polymerase; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Interleukin-1; Kinetics; L Cells; Mice; Molecular Sequence Data; Oligonucleotide Probes; Phosphoproteins; Polymerase Chain Reaction; Recombinant Proteins; RNA, Messenger; Second Messenger Systems; Taq Polymerase; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1989 |
The effect of azelastine on neutrophil and eosinophil generation of superoxide.
Topics: Adult; Calcimycin; Eosinophils; Free Radicals; Histamine H1 Antagonists; Humans; N-Formylmethionine Leucyl-Phenylalanine; Phthalazines; Protein Kinase C; Pyridazines; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Neutrophil membrane sulfhydryl groups are involved in stimulated neutrophil adherence to endothelium.
Topics: 4-Chloromercuribenzenesulfonate; Calcimycin; CD18 Antigens; Cell Adhesion; Cell Membrane; Endothelium, Vascular; Humans; In Vitro Techniques; Membrane Glycoproteins; Neutrophils; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate | 1989 |
Inhibition of human lymphocyte stimulation by visible light and phthalocyanine photosensitization: mitogen and wavelength dependency.
Topics: Calcimycin; Cells, Cultured; Humans; Indoles; Isoindoles; Light; Lymphocyte Activation; Phytohemagglutinins; Radiation-Sensitizing Agents; Tetradecanoylphorbol Acetate | 1989 |
T-cell response to phorbol ester PMA and calcium ionophore A23187 in Down's syndrome.
Topics: Adolescent; Adult; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD2 Antigens; Child; Down Syndrome; Humans; Lymphocyte Activation; Middle Aged; Receptors, Immunologic; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Characterization of the effects of phorbol esters on rat mast cell secretion.
Topics: Animals; Calcimycin; Calcium; Concanavalin A; Histamine Release; Kinetics; Mast Cells; Phorbol Esters; Phorbols; Rats; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1985 |
Phorbol ester (TPA) potentiates noradrenaline and acetylcholine-evoked amylase secretion in the rat pancreas.
Topics: Acetylcholine; Amylases; Animals; Bucladesine; Calcimycin; Drug Synergism; Norepinephrine; Pancreas; Phorbols; Rats; Tetradecanoylphorbol Acetate | 1985 |
Effect of pentagastrin on gastric mucosal histamine in dogs.
Topics: Animals; Calcimycin; Detergents; Dogs; Gastric Acid; Gastric Fistula; Gastric Mucosa; Histamine; Histamine Release; Male; Octoxynol; Pentagastrin; Polyethylene Glycols; Tetradecanoylphorbol Acetate | 1985 |
Stimulation and inhibition of secretion by phorbol myristate acetate in different cell types.
Topics: Animals; Blood Platelets; Calcimycin; Cell Line; Drug Interactions; Granulocytes; Histamine Release; Humans; Lysosomes; Mast Cells; N-Formylmethionine Leucyl-Phenylalanine; Phorbols; Rats; Serotonin; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Impairment of platelet behaviour by isosorbide dinitrate.
Topics: Adenosine Diphosphate; Calcimycin; Humans; Isosorbide Dinitrate; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetradecanoylphorbol Acetate | 1989 |
Trophoblast-derived immunoregulatory factor: demonstration of the biological function and the physicochemical characteristics of the factor derived from choriocarcinoma cell lines.
Topics: Calcimycin; Choriocarcinoma; Female; Humans; Lymphocyte Activation; Suppressor Factors, Immunologic; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Trophoblasts; Tumor Cells, Cultured; Uterine Neoplasms | 1989 |
Modulation of human neutrophil LTA hydrolase activity by phorbol myristate acetate.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Drug Interactions; Epoxide Hydrolases; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Tetradecanoylphorbol Acetate | 1987 |
Differential effects of nylon fibre adherence on the production of superoxide anion by human polymorphonuclear neutrophilic granulocytes stimulated with chemoattractants, ionophore A23187 and phorbol myristate acetate.
Topics: Calcimycin; Cell Adhesion; Chemotactic Factors; Humans; Neutrophils; Nylons; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Glucocorticoids suppress calcium mobilization and phospholipid hydrolysis in anti-Ig antibody-stimulated B cells.
Topics: Animals; Antibodies, Anti-Idiotypic; Antigen-Antibody Reactions; B-Lymphocytes; Calcimycin; Calcium; Cell Cycle; Dexamethasone; Glucocorticoids; Inositol Phosphates; Killer Cells, Natural; Lymphocyte Activation; Mice; Phosphatidylinositols; Receptors, Antigen, B-Cell; Receptors, Glucocorticoid; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Purification and properties of porcine polymorphonuclear cells.
Topics: Animals; Calcimycin; Cell Separation; Centrifugation, Density Gradient; Chemotaxis, Leukocyte; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Povidone; Silicon Dioxide; Swine; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Newly synthesized protein secretion in rat lacrimal gland: post-second messenger synergism.
Topics: Animals; Bucladesine; Calcimycin; Carbachol; Colforsin; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lacrimal Apparatus; Male; Papaverine; Proteins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1987 |
Effect of secretagogues on cytoplasmic free calcium in alveolar type II epithelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aminoquinolines; Animals; Calcimycin; Calcium; Colforsin; Cyclic AMP; Cytoplasm; Enzyme Activation; Epithelium; Ethers; Fluorescent Dyes; Ionomycin; Phosphatidylcholines; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Terbutaline; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C inhibition by sphingoid long-chain bases: effects on secretion in human neutrophils.
Topics: Calcimycin; Glucuronidase; Humans; In Vitro Techniques; Kinetics; Lactoferrin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1987 |
Comparative study of natural and synthetic retinoids as inhibitors of arachidonic acid release and metabolism in rat peritoneal macrophages.
Topics: Animals; Calcimycin; Dinoprostone; Fatty Acids, Unsaturated; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; Peritoneal Lavage; Phospholipases A; Prostaglandins E; Rats; Rats, Inbred Strains; Retinoids; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1987 |
Mechanisms of TSH release: studies with forskolin, phorbol ester and A23187.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Female; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thyrotropin | 1987 |
Stimulation of melatonin synthesis in ovine pineals in vitro.
Topics: Animals; Bucladesine; Calcimycin; Kinetics; Melatonin; Neuropeptide Y; Norepinephrine; Perfusion; Pineal Gland; Prazosin; Propranolol; Receptors, Adrenergic, beta; Sheep; Tetradecanoylphorbol Acetate; Tryptophan | 1988 |
Effect of phorbol ester and calcium ionophore on chloride secretion in canine tracheal epithelium.
Topics: Calcimycin; Chlorides; Cyclic AMP; Dinoprostone; Drug Synergism; Electric Conductivity; Epithelium; Indomethacin; Prostaglandins E; Protein Kinase C; Secretory Rate; Tetradecanoylphorbol Acetate; Trachea | 1987 |
Angiotensin II induces expression of the c-fos gene through protein kinase C activation and calcium ion mobilization in cultured vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Calcimycin; Calcium; Cells, Cultured; Enzyme Activation; Gene Expression Regulation; Male; Muscle, Smooth, Vascular; Phosphatidylinositols; Protein Kinase C; Proto-Oncogenes; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Na+-dependent elevation of the acidic cell surface pH (microclimate pH) of rat jejunal villus cells induced by cyclic nucleotides and phorbol ester: possible mediators of the regulation of the Na+/H+ antiporter.
Topics: Amiloride; Animals; Bucladesine; Calcimycin; Carrier Proteins; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Hydrogen-Ion Concentration; Jejunum; Male; Microvilli; Phorbol Esters; Phorbols; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Theophylline | 1988 |
Biosynthesis of platelet-activating factor in human polymorphonuclear leukocytes. Involvement of the cholinephosphotransferase pathway in response to the phorbol esters.
Topics: Acetyltransferases; Calcimycin; Choline; Diacylglycerol Cholinephosphotransferase; Diglycerides; Dithiothreitol; Dose-Response Relationship, Drug; Glyceryl Ethers; Humans; Neutrophils; Phorbol Esters; Phosphotransferases; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1988 |
Characterization of the neutrophil respiratory burst in atopy.
Topics: Calcimycin; Histamine; Humans; Hypersensitivity; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Inhibition of follicle-stimulating hormone- and adenosine-3',5'-cyclic monophosphate-induced progesterone production by calcium and protein kinase C in the rat ovary.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Calcium; Cells, Cultured; Cholera Toxin; Cyclic AMP; Female; Follicle Stimulating Hormone; Granulosa Cells; Progesterone; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1988 |
Angiotensin II-stimulated phosphatidylinositol turnover in rat adrenal glomerulosa cells has a complex dependence on calcium.
Topics: Adrenal Glands; Angiotensin II; Animals; Calcimycin; Calcium; Cyclic AMP; Cytosol; Inositol Phosphates; Kinetics; Male; Nifedipine; Phosphatidylinositols; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Cyclosporin A inhibits late steps of T lymphocyte activation after transmembrane signaling.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Calcimycin; Calcium; Calmodulin; Cells, Cultured; Concanavalin A; Cyclosporins; Inositol Phosphates; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred C3H; Myosin-Light-Chain Kinase; Protein Kinase C; Receptors, Concanavalin A; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Phorbol ester-induced differentiation permits productive human cytomegalovirus infection in a monocytic cell line.
Topics: Calcimycin; Cell Differentiation; Cell Line; Cytomegalovirus Infections; Disease Susceptibility; Drug Synergism; Humans; Interphase; Monocytes; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Modulation of acetyl-CoA:1-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PAF) acetyltransferase in human polymorphonuclears. The role of cyclic AMP-dependent and phospholipid sensitive, calcium-dependent protein kinases.
Topics: Acetyltransferases; Alkaline Phosphatase; Calcimycin; Enzyme Activation; Humans; Kinetics; Neutrophils; Protein Kinase C; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Platelet-activating factor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate stimulates the production of reactive oxygen intermediates in macrophages.
Topics: Calcimycin; Cells, Cultured; Diglycerides; Hydrolysis; Inositol Phosphates; Macrophages; Oxygen; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Platelet Activating Factor; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Developmental changes of the alpha-1-adrenergic receptor system in rat liver.
Topics: Aging; Animals; Binding, Competitive; Blood Glucose; Calcimycin; Gluconeogenesis; Glucose; Guanylyl Imidodiphosphate; In Vitro Techniques; Liver; Male; Norepinephrine; Prazosin; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate | 1987 |
Tumor necrosis factor receptors and cytocidal activity are down-regulated by activators of protein kinase C.
Topics: Animals; Calcimycin; Calcium; Cell Survival; Diglycerides; Enzyme Activation; HeLa Cells; Humans; L Cells; Mice; Protein Kinase C; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1988 |
Alteration in the regulation of neuronal muscarinic acetylcholine receptor number induced by chronic lithium in neuroblastoma cells.
Topics: Animals; Calcimycin; Carbachol; Cell Line; Cell Membrane; Chlorides; Kinetics; Lithium; Lithium Chloride; Mice; Neuroblastoma; Neurons; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1988 |
LTB4 production and lysosomal enzyme release by rat alveolar macrophages: effects of phagocytosis, receptor binding, and ionophore stimulation.
Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Leukotriene B4; Lysosomes; Macrophages; Masoprocol; Phagocytosis; Pulmonary Alveoli; Rabbits; Rats; Rats, Inbred Strains; Receptors, Complement; Receptors, Fc; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Rat neuropeptide Y precursor gene expression. mRNA structure, tissue distribution, and regulation by glucocorticoids, cyclic AMP, and phorbol ester.
Topics: Animals; Base Sequence; Brain Chemistry; Calcimycin; Cell Line; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Dexamethasone; Gene Expression Regulation; Glucocorticoids; Humans; Molecular Sequence Data; Neuropeptide Y; Phorbol Esters; Protein Precursors; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured | 1988 |
Proliferative effects of 12-O-tetradecanoylphorbol-13-acetate (TPA) and calcium ionophores on human large granular lymphocytes (LGL).
Topics: Antigens, Surface; Calcimycin; Cytotoxicity, Immunologic; Drug Synergism; Egtazic Acid; Ethers; Humans; Immune Sera; Immunosuppressive Agents; Interleukin-2; Ionomycin; Killer Cells, Natural; Kinetics; Lymphocyte Activation; Phenotype; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor Receptor Superfamily, Member 7 | 1988 |
Stimulus-dependent differences in superoxide anion generation by normal human eosinophils and neutrophils.
Topics: Adolescent; Adult; Calcimycin; Cell Separation; Centrifugation, Density Gradient; Cytochalasin B; Eosinophils; Humans; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Induction of cytosolic aspartate aminotransferase by glucagon in primary cultured rat hepatocytes.
Topics: Animals; Aspartate Aminotransferases; Bucladesine; Calcimycin; Cells, Cultured; Cyclic GMP; Cytosol; Dose-Response Relationship, Drug; Glucagon; Insulin; Liver; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Platelet activating factor and leukotriene B4 induce hyperpolarization of human endothelial cells but depolarization of neutrophils.
Topics: Calcimycin; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Leukotriene B4; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1988 |
Modulation of leukotriene release from human polymorphonuclear leucocytes by PMA and arachidonic acid.
Topics: Arachidonic Acids; Calcimycin; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Granulocytes; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; SRS-A; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Membrane-associated protein kinase C activity in superoxide-producing human polymorphonuclear leukocytes.
Topics: Calcimycin; Cell Membrane; Cells, Cultured; Diglycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Stimulation of cortisol production in isolated bovine zona fasciculata cells by phorbol ester: role of ion fluxes.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Amiloride; Angiotensin II; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Cattle; Hydrocortisone; In Vitro Techniques; Tetradecanoylphorbol Acetate | 1988 |
Cytosolic calcium, oxygen consumption and the intracellular pH of stimulated neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cell Separation; Concanavalin A; Cytoplasm; Digitonin; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Protons; Sodium; Tetradecanoylphorbol Acetate | 1988 |
Inhibition by islet-activating protein, pertussis toxin, of P2-purinergic receptor-mediated iodide efflux and phosphoinositide turnover in FRTL-5 cells.
Topics: Adenine Nucleotides; Adenosine Diphosphate Ribose; Adenosine Triphosphate; Animals; Calcimycin; Calcium; Cell Line; Cytosol; Guanosine Triphosphate; Inositol Phosphates; Iodides; Iodine Radioisotopes; Molecular Weight; Pertussis Toxin; Phosphatidylinositols; Rats; Receptors, Purinergic; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Virulence Factors, Bordetella | 1988 |
Control of human T-lymphocyte interleukin-2 production by a cAMP-dependent pathway.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenylyl Cyclases; Adolescent; Adult; Aged; Azides; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Immunologic; Female; Humans; Immunosuppressive Agents; Interleukin-1; Interleukin-2; Lymphocyte Activation; Male; Middle Aged; Phosphorylation; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Regulation of angiotensin II receptors in cultured rat ovarian granulosa cells by follicle-stimulating hormone and angiotensin II.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Aromatase; Calcimycin; Cells, Cultured; Cyclic GMP; Estradiol; Female; Follicle Stimulating Hormone; Granulosa Cells; Kinetics; Progesterone; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Testosterone; Tetradecanoylphorbol Acetate | 1988 |
Metabolism of leukotriene B4 by activated human polymorphonuclear granulocytes.
Topics: Calcimycin; Cell-Free System; Diazonium Compounds; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Immunologic; Receptors, Leukotriene B4; Sulfanilic Acids; Tetradecanoylphorbol Acetate; Thermolysin | 1988 |
T cell receptor/CD3 negative variants are unresponsive to stimulation through the Ly-6 encoded molecule, TAP.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antigens, Ly; Antigens, Surface; Calcimycin; Cell Separation; Clone Cells; Genetic Variation; Hybridomas; Lectins; Lymphocyte Activation; Mice; Mutation; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor Receptor Superfamily, Member 7 | 1988 |
Luminol-dependent photoemission from single neutrophil stimulated by phorbol ester and calcium ionophore--role of degranulation and myeloperoxidase.
Topics: Azides; Calcimycin; Cytoplasmic Granules; Drug Synergism; Humans; Luminescent Measurements; Luminol; Neutrophils; Peroxidase; Pyridazines; Radiation; Sodium Azide; Tetradecanoylphorbol Acetate | 1988 |
A study on the role of protein kinase C and intracellular calcium in the activation of superoxide generation.
Topics: Calcimycin; Calcium; Cell Membrane; Diglycerides; Enzyme Activation; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
A time-course study on superoxide generation and protein kinase C activation in human neutrophils.
Topics: Calcimycin; Cell Membrane; Ethers; Humans; In Vitro Techniques; Ionomycin; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Mechanism of stimulation of DNA synthesis induced by epinephrine in primary culture of adult rat hepatocytes.
Topics: Animals; Calcimycin; Cell Line; Cells, Cultured; Cyclic GMP; DNA; Epinephrine; Liver; Male; Rats; Rats, Inbred Strains; Sympatholytics; Tetradecanoylphorbol Acetate | 1988 |
Collagenase expression and endogenous activation in rabbit synovial fibroblasts stimulated by the calcium ionophore A23187.
Topics: Animals; Calcimycin; Cells, Cultured; Enzyme Activation; Fibroblasts; Gene Expression Regulation; Genes; Microbial Collagenase; Molecular Weight; Protease Inhibitors; Rabbits; RNA, Messenger; Synovial Fluid; Tetradecanoylphorbol Acetate | 1988 |
Regulation of aldosterone secretion by avian adrenocortical cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Animals; Calcimycin; Calcium Channel Blockers; Chickens; Corticosterone; Cyclic GMP; In Vitro Techniques; Male; Nitroprusside; Potassium; Rats; Sheep; Tetradecanoylphorbol Acetate | 1988 |
Effect of defibrotide on polymorphonuclear leukocytes: modulation of calcium entry and availability.
Topics: Biological Availability; Calcimycin; Calcium; Fibrinolytic Agents; Free Radicals; Humans; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polydeoxyribonucleotides; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Dieldrin activates rat neutrophils in vitro.
Topics: Animals; Calcimycin; Calcium; Dieldrin; L-Lactate Dehydrogenase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rats; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Leukotriene C4 production from human eosinophils in vitro. Role of eosinophil chemotactic factors on eosinophil activation.
Topics: Adult; Calcimycin; Cells, Cultured; Chemotactic Factors; Chemotactic Factors, Eosinophil; Enzyme Activation; Eosinophils; Female; Humans; Leukotriene B4; Male; Phosphatidylserines; Platelet Activating Factor; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1988 |
Studies on opsonized zymozan, FMLP, carbachol, PMA and A23187 stimulated respiratory burst of human PMNLs.
Topics: Adult; Aging; Calcimycin; Carbachol; Humans; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
PGE2-induced cyclic AMP accumulation in human CD4+ T cells is strongly enhanced during the CD2-mediated activatory process.
Topics: Antibodies, Monoclonal; Calcimycin; Calcium; Colforsin; Cyclic AMP; Dinoprostone; Humans; Isoproterenol; Lymphocyte Activation; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1988 |
Control of parathyroid hormone-degrading activity in the opossum kidney cell: possible involvement of protein kinase C.
Topics: Animals; Bucladesine; Calcimycin; Cell Line; Chromatography, High Pressure Liquid; Colforsin; Diglycerides; Enzyme Activation; Humans; Kidney; Opossums; Parathyroid Hormone; Peptide Fragments; Phorbol Esters; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1988 |
An analogue of creatine increases TRH-stimulated prolactin secretion and phosphoinositide hydrolysis in rat pituitary tumor cells.
Topics: Aminoquinolines; Animals; Calcimycin; Creatine; Dose-Response Relationship, Drug; Guanidines; Hydrolysis; Inositol Phosphates; Lactates; Lithium; Phosphatidylinositols; Phosphocreatine; Pituitary Neoplasms; Prolactin; Propionates; Rats; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1988 |
The degranulation response in differentiated HL-60 cells.
Topics: Calcimycin; Cell Differentiation; Cell Line; Cytoplasmic Granules; Granulocytes; Humans; Immunoglobulin G; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Peroxidase; Tetradecanoylphorbol Acetate | 1988 |
Endothelial cells: a source and target of oxidant damage.
Topics: Adenosine; Animals; Biological Factors; Calcimycin; Cattle; Cells, Cultured; Colony-Forming Units Assay; Endothelium, Vascular; Nitric Oxide; Staphylococcus aureus; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Control of c-fos and c-myc proto-oncogene induction in rat thyroid cells in culture.
Topics: Animals; Calcimycin; Cell Count; Cell Division; Cell Line; Cyclic AMP; DNA; Gene Expression Regulation; Genes, myc; Insulin; Insulin-Like Growth Factor I; Norepinephrine; Proto-Oncogenes; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymidine; Thyroglobulin; Thyroid Gland; Thyrotropin; Tritium | 1987 |
The inhibition of neutrophil granule enzyme secretion and chemotaxis by pertussis toxin.
Topics: Adenylate Cyclase Toxin; Animals; Bacterial Toxins; Bordetella pertussis; Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Cyclic AMP; Cytoplasmic Granules; Exocytosis; GTP-Binding Proteins; Neutrophils; Pertussis Toxin; Rabbits; Secretory Rate; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1985 |
Establishment of an assay system for the detection of translated materials of T-cell-replacing factor mRNA in Xenopus oocytes.
Topics: Animals; B-Lymphocytes; Calcimycin; Cell Differentiation; Cell Line; Drug Synergism; Female; Interleukin-2; Interleukin-5; Lymphokines; Oocytes; Poly A; Protein Biosynthesis; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Xenopus laevis | 1986 |
Activation of alpha 1-adrenoceptors, protein kinase C, or treatment with intracellular free Ca2+ elevating agents increases pineal phospholipase A2 activity. Evidence that protein kinase C may participate in Ca2+-dependent alpha 1-adrenergic stimulation o
Topics: Adrenergic alpha-Agonists; Animals; Arachidonic Acid; Arachidonic Acids; Bucladesine; Calcimycin; Calcium; Diglycerides; Lysophosphatidylcholines; Male; Norepinephrine; Organ Culture Techniques; Ouabain; Ovariectomy; Phenylephrine; Phospholipases; Phospholipases A; Phospholipases A2; Pineal Gland; Potassium; Protein Kinase C; Quinacrine; Rats; Tetradecanoylphorbol Acetate | 1987 |
Neuroendocrine regulation of thyrotropin release in cultured human pituitary cells.
Topics: Adolescent; Adult; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Humans; Male; Pituitary Gland, Anterior; Serotonin; Somatostatin; Tetradecanoylphorbol Acetate; Thyrotropin; Thyrotropin-Releasing Hormone; Verapamil | 1987 |
Prostaglandin E receptor enhancement of catecholamine release may be mediated by phosphoinositide metabolism in bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcimycin; Calcium; Catecholamines; Cattle; Chromaffin Granules; Chromaffin System; Cyclic AMP; Dinoprostone; Muscarine; Ouabain; Phosphatidylinositols; Prostaglandins E; Protein Kinase C; Receptors, Prostaglandin; Receptors, Prostaglandin E; Tetradecanoylphorbol Acetate | 1988 |
Rhein: an anthraquinone that modulates superoxide anion production from human neutrophils.
Topics: Adult; Anthraquinones; Calcimycin; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Alpha 1-adrenergic potentiation of vasoactive intestinal peptide stimulation of rat pinealocyte adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate: evidence for a role of calcium and protein kinase-C.
Topics: Adrenergic alpha-Agonists; Animals; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Female; Nifedipine; Norepinephrine; Ouabain; Pineal Gland; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1988 |
TAP transcription and phosphatidylinositol linkage mutants are defective in activation through the T cell receptor.
Topics: Animals; Antigens, Surface; Calcimycin; Clone Cells; Immunosorbent Techniques; Lymphocyte Activation; Membrane Lipids; Mice; Mutation; Nucleic Acid Hybridization; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Receptors, Antigen, T-Cell; RNA, Messenger; Structure-Activity Relationship; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thy-1 Antigens; Transcription, Genetic; Tumor Necrosis Factor Receptor Superfamily, Member 7 | 1988 |
Protein kinase C: subcellular redistribution by increased Ca2+ influx. Evidence that Ca2+-dependent subcellular redistribution of protein kinase C is involved in potentiation of beta-adrenergic stimulation of pineal cAMP and cGMP by K+ and A23187.
Topics: Adrenergic beta-Antagonists; Animals; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Kinetics; Norepinephrine; Pineal Gland; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1988 |
The multifunctional Ca2+/calmodulin-dependent protein kinase mediates Ca2+-dependent phosphorylation of tyrosine hydroxylase.
Topics: Adenosine; Adrenal Gland Neoplasms; Animals; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Cyclic AMP; Kinetics; Pheochromocytoma; Phosphorylation; Potassium; Protein Kinases; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase | 1988 |
Cyclic AMP-mediated alteration of the CD2 activation process in human T lymphocytes. Preferential inhibition of the phosphoinositide cycle-related transduction pathway.
Topics: Adenylyl Cyclases; Antigens, Differentiation, T-Lymphocyte; Bucladesine; Calcimycin; Calcium; CD2 Antigens; Cell Line; Cyclic AMP; Diglycerides; Dinoprostone; Humans; In Vitro Techniques; Inositol Phosphates; Lymphocyte Activation; Phosphatidylinositols; Receptors, Immunologic; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Phorbol ester and neomycin dissociate bradykinin receptor-mediated arachidonic acid release and polyphosphoinositide hydrolysis in Madin-Darby canine kidney cells. Evidence that bradykinin mediates noninterdependent activation of phospholipases A2 and C.
Topics: Animals; Arachidonic Acids; Bradykinin; Calcimycin; Cell Line; Dogs; Enzyme Activation; Hydrolysis; Kidney; Kinetics; Neomycin; Phorbols; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipases; Phospholipases A; Phospholipases A2; Receptors, Bradykinin; Receptors, Neurotransmitter; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Pertussis toxin-sensitive cholinergic inhibition of somatostatin release from canine D-cells.
Topics: Animals; Bucladesine; Calcimycin; Carbachol; Cells, Cultured; Colforsin; Dogs; Epinephrine; Gastric Fundus; Gastric Mucosa; Kinetics; Pertussis Toxin; Reference Values; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Cloned helper T lymphocytes exposed to interleukin 2 become unresponsive to antigen and concanavalin A but not to calcium ionophore and phorbol ester.
Topics: Animals; Antigens; Calcimycin; Cell Line; Concanavalin A; Interleukin-2; Lymphocyte Activation; Lymphoma; Mice; Mice, Inbred CBA; Receptors, Antigen, T-Cell; Recombinant Proteins; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1986 |
The influence of activating hormones on human platelet membrane Ca2+-ATPase activity.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Calcimycin; Calcium-Transporting ATPases; Cell Membrane; Colforsin; Ethers; Humans; Ionomycin; Kinetics; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1986 |
PMA alone induces proliferation of some murine T cell clones but not others.
Topics: Animals; Calcimycin; Clone Cells; Drug Synergism; Interleukin-2; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred Strains; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1986 |
Selection and characterization of T-cell variants lacking molecules involved in T-cell activation (T3 T-cell receptor, T44, and T11): analysis of the functional relationship among different pathways of activation.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Calcimycin; CD3 Complex; Cell Line; Complement System Proteins; Gene Expression Regulation; Interleukin-2; Lymphocyte Activation; Phytohemagglutinins; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Selective activation of helper and cytolytic T-cell functions of L3T4+ clones with either antireceptor antibody or phorbol ester and ionophore.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Calcimycin; Clone Cells; Cytotoxicity, Immunologic; Lymphocyte Activation; Mice; Peptide Fragments; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1987 |
Activation of protein kinase C down-regulates IFN-gamma receptors.
Topics: Animals; Calcimycin; Cell Line; Diglycerides; Enzyme Activation; Interferon-gamma; Kinetics; Protein Kinase C; Receptors, Immunologic; Receptors, Interferon; Tetradecanoylphorbol Acetate | 1987 |
Requirements for triggering of lysis by cytolytic T lymphocyte clones.
Topics: Animals; Antigen-Antibody Reactions; Antigens, Ly; Antigens, Surface; Calcimycin; Calcium; Cells, Cultured; Clone Cells; Cytotoxicity, Immunologic; Drug Synergism; Lymphocyte Function-Associated Antigen-1; Mice; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; Temperature; Tetradecanoylphorbol Acetate | 1987 |
Interleukin 2 inhibits antigen-stimulated lymphokine synthesis in helper T cells by inhibiting calcium-dependent signalling.
Topics: Animals; Antigens; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Calcimycin; Calcium; Gene Expression Regulation; Interferon-gamma; Interleukin-2; Interleukin-3; Isoantigens; Lymphocyte Activation; Lymphokines; Mice; RNA, Messenger; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1987 |
Adhesion of lymphoid cell lines to fibronectin-coated substratum: biochemical and physiological characterization and the identification of a 140-kDa fibronectin receptor.
Topics: Animals; Calcimycin; Cations, Divalent; Cell Adhesion; Cell Differentiation; Cell Line; Cycloheximide; Cytochalasin B; Fibronectins; Humans; Lymphocytes; Lymphoma; Multiple Myeloma; Receptors, Fibronectin; Receptors, Immunologic; Tetradecanoylphorbol Acetate; Trypsin | 1987 |
Differential regulation of T cell receptor gamma genes in immature thymocyte populations.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Gene Expression Regulation; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, gamma-delta; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
PCP and analogs prevent the proliferative response of T lymphocytes by lowering IL2 production. An effect related to the blockade of mitogen-triggered enhancement of free cytosolic calcium concentration.
Topics: Animals; Calcimycin; Calcium; Concanavalin A; Cytosol; DNA Replication; Humans; Interleukin-1; Interleukin-2; Lymphocyte Activation; Macrophages; Membrane Potentials; Mice; Phencyclidine; Receptors, Antigen, T-Cell; T-Lymphocytes; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1987 |
Modulation of histamine release from canine fundic mucosal mast cells.
Topics: Adenosine; Animals; Calcimycin; Calcium; Cells, Cultured; Concanavalin A; Dogs; Extracellular Space; Gastric Fundus; Gastric Mucosa; Gastrins; Histamine; Liver; Mast Cells; Parasympathomimetics; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate | 1988 |
Rapid phosphorylation of MAP-2-related cytoplasmic and nuclear Mr 300,000 protein by serine kinases after growth stimulation in quiescent cells.
Topics: Animals; Calcimycin; Cell Compartmentation; Cell Cycle; Cell Nucleus; Chemical Precipitation; Cytoplasm; Diglycerides; Egtazic Acid; Epidermal Growth Factor; Growth Substances; Immunologic Techniques; Insulin; Microtubule-Associated Proteins; Molecular Weight; Phosphoproteins; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Tetradecanoylphorbol Acetate; Time Factors; Transferrin; Tretinoin | 1988 |
Production of tumor necrosis factor/cachectin by human T cell lines and peripheral blood T lymphocytes stimulated by phorbol myristate acetate and anti-CD3 antibody.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Complex; Cell Line; Gene Expression Regulation; Humans; Leukemia; Lymphotoxin-alpha; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1988 |
Immunosuppressive lymphokine derived from natural suppressor cells.
Topics: Animals; Calcimycin; Culture Media; DNA Replication; Female; Hydrogen-Ion Concentration; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Weight; Rats; Rats, Inbred Lew; Suppressor Factors, Immunologic; T-Lymphocytes, Regulatory; Temperature; Tetradecanoylphorbol Acetate | 1988 |
Trypanosoma cruzi-induced suppression of IL-2 production. I. Evidence for the presence of IL-2-producing cells.
Topics: Animals; Calcimycin; Calcium; Chagas Disease; Concanavalin A; Ethers; Female; Immune Tolerance; Interleukin-2; Ionomycin; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Protein Kinase C; Spleen; T-Lymphocytes; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Trypanosoma cruzi | 1988 |
Calcium influx and the Ca2+-calmodulin complex are involved in interferon-gamma-induced expression of HLA class II molecules on HL-60 cells.
Topics: Calcimycin; Calcium; Calmodulin; Cell Line; Egtazic Acid; HLA-D Antigens; Humans; Interferon-gamma; Leukemia, Myeloid, Acute; Receptors, Immunologic; Receptors, Interferon; RNA, Messenger; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcimycin; Clone Cells; Concanavalin A; Humans; Interferon-gamma; Interleukin-2; Interleukin-4; Interleukins; Isoantigens; Lymphocyte Activation; Phenotype; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Translocation of protein kinase C in rat basophilic leukemic cells induced by phorbol ester or by aggregation of IgE receptors.
Topics: Animals; Basophils; Biological Transport; Calcimycin; Calcium; Cell Line; Exocytosis; Extracellular Space; Haptens; Immunoglobulin E; Leukemia; Protein Kinase C; Rats; Receptor Aggregation; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate | 1988 |
Differentiation of HL-60 cells is associated with an increase in the 35-kDa protein lipocortin I.
Topics: Annexins; Calcimycin; Cell Differentiation; Cell Line; Cytosol; Glycoproteins; Humans; Macrophages; Neutrophils; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Biochemical models of gamma-interferon action: altered expression of transferrin receptors on murine peritoneal macrophages after treatment in vitro with PMA or A23187.
Topics: Animals; Calcimycin; Cells, Cultured; Interferon-gamma; Kinetics; Macrophages; Mice; Mice, Inbred C57BL; Phorbol Esters; Phorbols; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin | 1985 |
Defective triggering of polymorphonuclear leukocyte oxidative metabolism by Legionella pneumophila toxin.
Topics: Bacterial Toxins; Calcimycin; Cell Membrane; Hexosephosphates; Humans; Legionella; Membrane Potentials; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Functional defects in phagocytic cells following thermal injury. Application of flow cytometric analysis.
Topics: Animals; Burns; Calcimycin; Carbocyanines; Flow Cytometry; Fluoresceins; In Vitro Techniques; Leukocyte Count; Macrophages; Neutrophils; Oxygen; Phagocytes; Plasma; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Prostaglandins E1 and E2 enhance the stimulation of superoxide release by 1-oleoyl-2-acetylglycerol from human neutrophils.
Topics: Alprostadil; Calcimycin; Diglycerides; Dinoprostone; Enzyme Activation; Glycerides; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E; Protein Kinase C; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils.
Topics: Acetylglucosaminidase; Animals; Calcimycin; Calcium; Cytoplasmic Granules; Leukotriene B4; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbols; Rabbits; Sodium; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1985 |
Cytochrome b translocation to human neutrophil plasma membranes and superoxide release. Differential effects of N-formylmethionylleucylphenylalanine, phorbol myristate acetate, and A23187.
Topics: Calcimycin; Cell Fractionation; Cell Membrane; Child; Cytochrome b Group; Cytoplasmic Granules; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Inhibition of hepatic alpha 1-adrenergic effects and binding by phorbol myristate acetate.
Topics: Animals; Calcimycin; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Phentolamine; Phorbols; Phosphorylase a; Propranolol; Protein Kinase C; Protein Kinases; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Time Factors; Vasopressins | 1985 |
Pertussis but not cholera toxin inhibits the stimulated increase in actin association with the cytoskeleton in rabbit neutrophils: role of the "G proteins" in stimulus-response coupling.
Topics: Actins; Animals; Bacterial Toxins; Calcimycin; Calcium; Cholera Toxin; Cytoskeleton; GTP-Binding Proteins; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein Binding; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1985 |
EGF receptor affinity is regulated by intracellular calcium and protein kinase C.
Topics: Animals; Calcimycin; Calcium; Carcinoma, Squamous Cell; Cell Line; Egtazic Acid; Epidermal Growth Factor; ErbB Receptors; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1985 |
Phorbol 12-myristate, 13-acetate potentiates the action of the calcium ionophore in stimulating arachidonic acid release and production of phosphatidic acid in rabbit neutrophils.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Drug Synergism; Neutrophils; Phorbols; Phosphatidic Acids; Phosphatidylinositol Phosphates; Phosphatidylinositols; Rabbits; Sodium Chloride; Tetradecanoylphorbol Acetate | 1985 |
Phorbol myristate acetate inhibits thrombin-stimulated Ca2+ mobilization and phosphatidylinositol 4,5-bisphosphate hydrolysis in human platelets.
Topics: Aminoquinolines; Blood Platelets; Calcimycin; Calcium; Humans; Lipid Metabolism; Phorbol Esters; Phorbols; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Thrombin | 1985 |
Role of enhanced inositol phospholipid metabolism in neutrophil activation.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Proteins; Calcimycin; Calcium; Guinea Pigs; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phosphorylation; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Effects of chemotactic factors and other agents on the amounts of actin and a 65,000-mol-wt protein associated with the cytoskeleton of rabbit and human neutrophils.
Topics: Actins; Aminoquinolines; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cytoskeleton; Glucose; Humans; Leukotriene B4; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Tetradecanoylphorbol Acetate; Urea; Water-Electrolyte Balance | 1985 |
Activation-associated alterations in neutrophil pyridine nucleotide levels: a potential regulatory role for calcium and calmodulin.
Topics: Calcimycin; Calcium; Calmodulin; Female; Humans; In Vitro Techniques; Male; NADP; Neutrophils; Protein Kinase C; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Stimulation of the adenosine 3',5'-monophosphate and the Ca2+ messenger systems together reverse dopaminergic inhibition of prolactin release.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Dopamine; Female; Kinetics; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1985 |
Diverse involvements of Ni protein in superoxide anion production in polymorphonuclear leukocytes depending on the type of membrane stimulants.
Topics: Adenylate Cyclase Toxin; Animals; Bacterial Toxins; Calcimycin; Calcium; Concanavalin A; Female; GTP-Binding Proteins; Guinea Pigs; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1985 |
Angiotensin II and phorbol ester enhance isoproterenol- and vasoactive intestinal peptide (VIP)-induced cyclic AMP accumulation in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Calcimycin; Cyclic AMP; Isoproterenol; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Tetradecanoylphorbol Acetate; Theophylline; Vasoactive Intestinal Peptide | 1985 |
Combined effect of phorbol ester and, A23187 or dibutyryl cyclic AMP on pepsinogen secretion from isolated gastric glands.
Topics: Animals; Bucladesine; Calcimycin; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Gastric Mucosa; Guinea Pigs; Pepsinogens; Phorbols; Protein Kinase C; Protein Kinases; Sincalide; Tetradecanoylphorbol Acetate | 1985 |
Leukotriene B4 and 12-hydroxyeicosatetraenoic acid stimulate epidermal proliferation in vivo in the guinea pig.
Topics: Animals; Calcimycin; Cell Division; Ear; Epidermal Cells; Guinea Pigs; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Stereoisomerism; Tetradecanoylphorbol Acetate | 1985 |
Effect of benzydamine on exocytosis and respiratory burst in human neutrophils and mononuclear phagocytes.
Topics: Benzydamine; Calcimycin; Cytochalasin B; Cytoplasmic Granules; Exocytosis; Glucuronidase; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Phagocytes; Pyrazoles; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Phorbol ester stimulates calcitonin secretion synergistically with A23187, and additively with dibutyryl cyclic AMP in a rat C-cell line.
Topics: Animals; Bucladesine; Calcimycin; Calcitonin; Cell Line; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Phorbols; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1985 |
Inhibition by islet-activating protein of a chemotactic peptide-induced early breakdown of inositol phospholipids and Ca2+ mobilization in guinea pig neutrophils.
Topics: Adenylate Cyclase Toxin; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Dose-Response Relationship, Drug; Guinea Pigs; Inositol Phosphates; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphatidylinositols; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases; Virulence Factors, Bordetella | 1985 |
Tumor promoters in conjunction with calcium ionophores mimic antigenic stimulation by reactivation of alloantigen-primed murine T lymphocytes.
Topics: Animals; Calcimycin; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; Cyclic AMP; Cyclosporins; Cytotoxicity, Immunologic; Drug Synergism; Egtazic Acid; Female; Immunosuppressive Agents; Interleukin-2; Isoantigens; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Protein Kinase C; Rats; Rats, Inbred Lew; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
Activation of Na+/H+ exchange in cultured fibroblasts: synergism and antagonism between phorbol ester, Ca2+ ionophore, and growth factors.
Topics: Animals; Biological Transport; Calcimycin; Carrier Proteins; Cells, Cultured; Drug Synergism; Growth Substances; Humans; Mice; Phorbols; Protein Kinase C; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1985 |
Atrial natriuretic peptide secretion: synergistic effect of phorbol ester and A23187.
Topics: Animals; Atrial Natriuretic Factor; Calcimycin; Drug Synergism; In Vitro Techniques; Male; Myocardium; Perfusion; Phorbol Esters; Phosphatidylinositols; Radioimmunoassay; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1985 |
Dopamine inhibits prolactin release when cyclic adenosine 3',5'-monophosphate levels are elevated.
Topics: Animals; Calcimycin; Colforsin; Cyclic AMP; Dopamine; Female; Fluorescent Antibody Technique; Microscopy, Fluorescence; Pituitary Neoplasms; Prolactin; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1986 |
Peroxide formation and glucose oxidation in calf thyroid slices: regulation by protein kinase-C and cytosolic free calcium.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Calcium; Cattle; Cyclic AMP; Cytosol; Glucose; Hydrogen Peroxide; Lithium; Oxidation-Reduction; Protein Kinase C; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Verapamil | 1986 |
Regulation of thyroxine 5'-deiodinase by thyroid hormones and activators of protein kinase C in GH4C1 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Cell Line; Colforsin; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Hypothyroidism; Iodide Peroxidase; Phorbol Esters; Pituitary Neoplasms; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thyroid Hormones; Thyrotropin-Releasing Hormone; Thyroxine; Trifluoperazine; Triiodothyronine; Triiodothyronine, Reverse | 1986 |
The role of Ca2+ and Ca2+-activated phospholipid-dependent protein kinase in degranulation of human neutrophils.
Topics: Bucladesine; Calcimycin; Calcium; Calmodulin; Cytoplasmic Granules; Dibutyryl Cyclic GMP; Diglycerides; Drug Interactions; Egtazic Acid; Enzyme Activation; Glucuronidase; Lactoferrin; Muramidase; Neutrophils; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate; Vacuoles | 1985 |
Regulation of free cytosolic Ca2+ in the peptic and parietal cells of the rabbit gastric gland.
Topics: Aminopyrine; Aminoquinolines; Animals; Atropine; Bombesin; Bucladesine; Calcimycin; Calcium; Calcium Chloride; Carbachol; Cytosol; Gastric Mucosa; Lanthanum; Nifedipine; Parietal Cells, Gastric; Pepsin A; Rabbits; Sincalide; Tetradecanoylphorbol Acetate | 1986 |
Effect of the calcium ionophore A23187 on superoxide generation in phorbol ester stimulated human neutrophils.
Topics: Calcimycin; Calcium; Humans; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Lysosomes; Neutrophils; Oxygen Consumption; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Superoxides; Tetradecanoylphorbol Acetate | 1985 |
Hyperoxia alters effect of calcium on rat alveolar macrophage superoxide production.
Topics: Animals; Calcimycin; Calcium; Concanavalin A; In Vitro Techniques; Macrophages; Male; Oxygen; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate; Verapamil | 1986 |
Superoxide anion release by human endothelial cells: synergism between a phorbol ester and a calcium ionophore.
Topics: Anions; Calcimycin; Dimethyl Sulfoxide; Drug Synergism; Endothelium; Humans; Osmolar Concentration; Phorbols; Superoxides; Tetradecanoylphorbol Acetate; Umbilical Veins | 1986 |
Oxygen radical production by neutrophils from patients with bacterial infection and rheumatoid arthritis. Measurement of hydrogen peroxide may most accurately represent enhancement of oxygen radical production during infection.
Topics: Arthritis, Rheumatoid; Bacterial Infections; C-Reactive Protein; Calcimycin; Cytochalasin B; Free Radicals; Humans; Hydrogen Peroxide; Leukocyte Count; Neutrophils; Oxygen; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Calcium modulation activates Epstein-Barr virus genome in latently infected cells.
Topics: Aminoquinolines; Burkitt Lymphoma; Calcimycin; Calcium; Cell Line; Cell Transformation, Viral; Culture Media; Ethers; Fluorescent Dyes; Genes, Viral; Herpesvirus 4, Human; Humans; Ionomycin; Kinetics; Tetradecanoylphorbol Acetate | 1986 |
Protein kinase C promotes the phosphorylation of immunoprecipitated middle T antigen from polyoma-transformed cells.
Topics: Animals; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Calcimycin; Cell Transformation, Viral; Densitometry; Mice; Molecular Weight; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphorylation; Polyomavirus; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Retroviridae Proteins; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates; Vanadium | 1986 |
The role of calcium in the secretion of surfactant by rat alveolar type II cells.
Topics: Animals; Calcimycin; Calcium; Cyclic AMP; In Vitro Techniques; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Tetradecanoylphorbol Acetate | 1986 |
Effect of phorbol esters on glucagon secretion from a glucagon-secreting clonal cell line. Synergistic effects of A23187 and theophylline.
Topics: Adenoma, Islet Cell; Animals; Calcimycin; Cell Line; Clone Cells; Cricetinae; Drug Synergism; Glucagon; In Vitro Techniques; Insulinoma; Pancreatic Neoplasms; Phorbols; Tetradecanoylphorbol Acetate; Theophylline | 1986 |
Nerve growth factor rapidly induces c-fos mRNA in PC12 rat pheochromocytoma cells.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Cell Differentiation; Cell Line; Cycloheximide; Gene Expression Regulation; Kinetics; Nerve Growth Factors; Pheochromocytoma; Proto-Oncogene Proteins; Rats; Receptors, Cell Surface; Receptors, Nerve Growth Factor; RNA, Messenger; Tetradecanoylphorbol Acetate | 1986 |
Role of calcium on TPA-induced secretion of ACTH and PGE2 by pituitary cells: effect of dexamethasone.
Topics: Adrenocorticotropic Hormone; Animals; Calcimycin; Calcium; Dexamethasone; Dinoprostone; Dose-Response Relationship, Drug; Male; Phorbols; Phospholipases A; Phospholipases A2; Pituitary Gland, Anterior; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Biochemical models of interferon-gamma-mediated macrophage activation: independent regulation of lymphocyte function associated antigen (LFA)-1 and I-A antigen on murine peritoneal macrophages.
Topics: Animals; Antigen-Presenting Cells; Antigens, Surface; Calcimycin; Cytotoxicity, Immunologic; Dose-Response Relationship, Immunologic; Female; Histocompatibility Antigens Class II; Interferon-gamma; Lymphocyte Function-Associated Antigen-1; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
DNA strand breaks in human leukocytes induced by superoxide anion, hydrogen peroxide and tumor promoters are repaired slowly compared to breaks induced by ionizing radiation.
Topics: Benzamides; Calcimycin; DNA; DNA Repair; Humans; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; Neutrophils; Phorbols; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Gonadotropin-releasing hormone activates a rapid Ca2+-independent phosphodiester hydrolysis of polyphosphoinositides in pituitary gonadotrophs.
Topics: Animals; Calcimycin; Calcium; Ethers; Female; Gonadotropin-Releasing Hormone; Inositol Phosphates; Ionomycin; Lithium; Pertussis Toxin; Phosphatidylinositol Phosphates; Phosphatidylinositols; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1986 |
Differential effects of mepacrine, chloroquine and hydroxychloroquine on superoxide anion generation, phospholipid methylation and arachidonic acid release by human blood monocytes.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Survival; Chloroquine; Fluorides; Humans; Hydroxychloroquine; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phospholipids; Quinacrine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Regulation of intracellular pH in human platelets. Effects of thrombin, A23187, and ionomycin and evidence for activation of Na+/H+ exchange and its inhibition by amiloride analogs.
Topics: Amiloride; Blood Platelets; Body Fluids; Calcimycin; Carrier Proteins; Ethers; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ionomycin; Nigericin; Prostaglandin D2; Prostaglandins D; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thrombin; Time Factors | 1986 |
Role of icosanoids in alveolar macrophage phagocytosis and aggregation.
Topics: Animals; Arachidonic Acids; Asbestos; Calcimycin; Cell Aggregation; Cyclooxygenase Inhibitors; Erythrocytes; Humans; Immunoglobulins; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Phagocytosis; Propionates; Pulmonary Alveoli; Rats; Rho(D) Immune Globulin; Tetradecanoylphorbol Acetate | 1986 |
A comparative study on the effects of inhibitors of the lipoxygenase pathway on neutrophil function. Inhibitory effects on neutrophil function may not be attributed to inhibition of the lipoxygenase pathway.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Benzoquinones; Calcimycin; Chemotaxis, Leukocyte; Epoprostenol; Humans; Hydroxides; Hydroxyl Radical; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinones; Tetradecanoylphorbol Acetate; Umbelliferones | 1986 |
The mechanisms by which phorbol ester inhibits LH stimulation of progesterone production in rat granulosa cells.
Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Animals; Bucladesine; Calcimycin; Cholera Toxin; Female; Gonadotropin-Releasing Hormone; Granulosa Cells; Luteinizing Hormone; Progesterone; Rats; Tetradecanoylphorbol Acetate | 1986 |
Interaction of IL 1 and TPA in modulation of eosinophil function.
Topics: Calcimycin; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Eosinophils; Exocytosis; Humans; In Vitro Techniques; Interleukin-1; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of neutrophil superoxide formation by 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7), and inhibitor of protein kinase-C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Cytoplasm; Humans; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
A phorbol ester and 1-oleoyl-2-acetylglycerol induce Na+/H+ exchange in human platelets.
Topics: Alprostadil; Biological Transport; Blood Platelets; Bucladesine; Calcimycin; Carrier Proteins; Diglycerides; Epoprostenol; Glycerides; Humans; In Vitro Techniques; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thrombin; Trifluoperazine | 1986 |
Modulation by phorbol myristate acetate of arachidonic acid release and leukotriene synthesis by human polymorphonuclear leukocytes stimulated with A23187.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Drug Synergism; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Rapid modulation of tumor necrosis factor membrane receptors by activators of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Cells, Cultured; Diglycerides; Glycoproteins; Humans; Isoquinolines; Lymphocyte Activation; Piperazines; Protein Kinase C; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1986 |
A phorbol ester, phorbol 12-myristate 13-acetate, and a calcium ionophore, A23187, can mimic the luteolytic effect of prostaglandin F2 alpha in isolated rat luteal cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Calcimycin; Corpus Luteum; Cyclic AMP; Dinoprost; Female; In Vitro Techniques; Kinetics; Luteinizing Hormone; Phorbol Esters; Progesterone; Prostaglandins F; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Effects of disodium ethane-1-hydroxy-1,1-diphosphonate (EHDP) on interleukin 1 production by macrophages.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Calcimycin; Cell Adhesion; Etidronic Acid; Guinea Pigs; Interleukin-1; Lipopolysaccharides; Macrophages; Superoxides; Tetradecanoylphorbol Acetate | 1986 |
Stimulatory and inhibitory effects of protein kinase C activation and calcium ionophore on cultured pig Leydig cells.
Topics: Animals; Calcimycin; Cells, Cultured; Cyclic AMP; Diglycerides; Enzyme Activation; Leydig Cells; Male; Protein Kinase C; Receptors, LH; Swine; Testosterone; Tetradecanoylphorbol Acetate | 1987 |
Augmentation of c-fos mRNA expression by activators of protein kinase C in fresh, terminally differentiated resting macrophages.
Topics: Calcimycin; Cytotoxicity, Immunologic; Diglycerides; Enzyme Activation; Gene Expression Regulation; Interferon Type I; Interferon-gamma; Kinetics; Macrophages; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogenes; RNA, Messenger; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Angiotensin II effect on cytosolic pH in cultured rat vascular smooth muscle cells.
Topics: Amiloride; Aminoquinolines; Angiotensin II; Animals; Calcimycin; Carrier Proteins; Cytosol; Dose-Response Relationship, Drug; Fluoresceins; Hydrogen-Ion Concentration; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1987 |
Phorbol esters and A23187 regulate Na+-K+-pump activity in pancreatic acinar cells.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Carbachol; Diglycerides; Dose-Response Relationship, Drug; Guinea Pigs; Ouabain; Pancreas; Protein Kinase C; Secretin; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 1987 |
Is histamine potentiation of adenosine-stimulated cyclic AMP accumulation in guinea-pig cerebral cortical slices mediated by products of inositol phospholipid breakdown?
Topics: Adenosine; Animals; Calcimycin; Cerebral Cortex; Cyclic AMP; Drug Synergism; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Male; Phosphatidylinositols; Tetradecanoylphorbol Acetate | 1987 |
A dual role for calcium in regulation of superoxide generation by stimulated rat alveolar macrophages.
Topics: Animals; Calcimycin; Calcium; Concanavalin A; In Vitro Techniques; Kinetics; Macrophages; Protein Kinase C; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Phorbol myristate acetate and the calcium ionophore A23187 synergistically induce release of LTB4 by human neutrophils: involvement of protein kinase C activation in regulation of the 5-lipoxygenase pathway.
Topics: Adult; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Drug Synergism; Enzyme Activation; Humans; Leukotriene B4; Membrane Proteins; Neutrophils; Protein Kinase C; Secretory Rate; Tetradecanoylphorbol Acetate | 1987 |
Phorbol ester-induced inhibition of cyclic GMP formation mediated by muscarinic receptors in murine neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carbachol; Cell Line; Cyclic GMP; Dose-Response Relationship, Drug; Histamine; Isoquinolines; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Piperazines; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1987 |
Role of second messengers in the regulation of glucagon secretion from isolated rat islets of Langerhans.
Topics: Animals; Arginine; Calcimycin; Calcium; Colforsin; Cyclic AMP; Diglycerides; Drug Interactions; Glucagon; Glycerides; Islets of Langerhans; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Trifluoperazine | 1987 |
Biphasic effects of dibutyryl cyclic adenosine 3',5'-monophosphate on synergistic stimulation of DNA synthesis by diacylglycerol, and the ionophore A23187 in guinea pig lymphocytes.
Topics: Animals; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Diglycerides; DNA; Glycerides; Guinea Pigs; Lymphocytes; Ornithine Decarboxylase; Tetradecanoylphorbol Acetate | 1987 |
Signalling for increased cytoskeletal actin in neutrophils.
Topics: Actins; Animals; Calcimycin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Pertussis Toxin; Platelet Activating Factor; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
The role of cAMP and calcium in the stimulation of proliferation of immature erythroblasts by erythropoietin.
Topics: Animals; Bucladesine; Calcimycin; Calcium; Cell Division; Cells, Cultured; Cyclic AMP; DNA; Egtazic Acid; Erythroblasts; Erythropoiesis; Erythropoietin; Hemoglobins; Isoproterenol; Rabbits; Tetradecanoylphorbol Acetate | 1987 |
Action mechanism of inhibin in vitro--cycloheximide mimics inhibin actions on pituitary cells.
Topics: Animals; Bucladesine; Calcimycin; Cells, Cultured; Cholera Toxin; Cycloheximide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Inhibins; Luteinizing Hormone; Pituitary Gland, Anterior; Rats; Secretory Rate; Tetradecanoylphorbol Acetate | 1987 |
Neutrophils become refractory to phorbol myristate acetate when treated with Ca2+-ionophore and Ca2+.
Topics: Aminoquinolines; Calcimycin; Calcium; Drug Resistance; Egtazic Acid; Humans; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
Calcium and inositolphosphates in the activation of T cell-mediated cytotoxicity.
Topics: Animals; Calcimycin; Calcium; Cell Line; Egtazic Acid; Fluorescence; Gammaretrovirus; Lymphocyte Activation; Lymphoma; Mice; Mice, Inbred C57BL; Moloney murine sarcoma virus; Phosphatidylinositol Phosphates; Phosphatidylinositols; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Virus Infections | 1987 |
Charge-dependent regulation of NADPH oxidase activity in guinea-pig polymorphonuclear leukocytes.
Topics: Amines; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Membrane; Electrochemistry; Enzyme Activation; Guinea Pigs; Hydrocarbons; Intracellular Membranes; Male; Myristic Acid; Myristic Acids; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C is involved in adrenergic stimulation of pineal cGMP accumulation.
Topics: Animals; Calcimycin; Cyclic AMP; Cyclic GMP; Isoproterenol; Nifedipine; Ouabain; Pineal Gland; Potassium; Protein Kinase C; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Tetradecanoylphorbol Acetate | 1987 |
Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate.
Topics: Calcimycin; Calcium; Cyclic AMP; Cytoplasm; Dinoprostone; Enzyme Activation; Humans; Immune Tolerance; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Prostaglandins E; Protein Kinase C; Receptors, Immunologic; Receptors, Interleukin-2; Receptors, Transferrin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Mitogen stimulation of Na+-H+ exchange: differential involvement of protein kinase C.
Topics: Blood Physiological Phenomena; Calcimycin; Carrier Proteins; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Humans; Mitogens; Protein Kinase C; Skin; Sodium-Hydrogen Exchangers; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1987 |
Both protein kinase C and calcium mediate activation of the Na+/H+ antiporter in Chinese hamster embryo fibroblasts.
Topics: Animals; Calcimycin; Calcium; Carrier Proteins; Cell Line; Cricetinae; Embryo, Mammalian; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Hydrogen-Ion Concentration; Protein Kinase C; Sodium-Hydrogen Exchangers; Sulfonamides; Tetradecanoylphorbol Acetate; Thrombin; Trifluoperazine | 1987 |
Regulation of HLA class II antigen expression: intracellular signaling molecules responsible for the regulation by IFN-gamma and cross-linking of Fc receptors in HL-60 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Neoplasm; Calcimycin; Calcium; Calmodulin; Cell Line; Cyclic AMP; Gene Expression Regulation; Histocompatibility Antigens Class II; Humans; Immunoglobulin G; Interferon-gamma; Isoquinolines; Leukemia, Myeloid, Acute; Male; Middle Aged; Piperazines; Protein Kinase C; Receptors, Fc; Recombinant Proteins; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Calcium-dependent and -independent tumoricidal activities of polymorphonuclear leukocytes induced by a linear beta-1,3-D-glucan and phorbol myristate acetate in mice.
Topics: Adjuvants, Immunologic; Animals; Calcimycin; Calcium; Cytotoxicity, Immunologic; Egtazic Acid; Glucans; Hydrogen Peroxide; Magnesium; Male; Mice; Mice, Inbred C3H; Neutrophils; Phorbols; Tetradecanoylphorbol Acetate | 1986 |
B cell activation. VII. Independent and synergistic effects of mobilized calcium and diacylglycerol on membrane potential and I-A expression.
Topics: Animals; B-Lymphocytes; Calcimycin; Calcium; Cross-Linking Reagents; Diglycerides; Dose-Response Relationship, Immunologic; Drug Synergism; Glycerides; Histocompatibility Antigens Class II; Hydrolysis; Lymphocyte Activation; Membrane Potentials; Mice; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Extracellular calcium requirement for promotion of transformation in JB6 cells.
Topics: Animals; Calcimycin; Calcium; Cell Line; Cell Transformation, Neoplastic; Egtazic Acid; Extracellular Space; Lanthanum; Mice; Nifedipine; Phorbols; Tetradecanoylphorbol Acetate | 1986 |
Activation of IL 1-dependent and IL 1-independent T cell lines by calcium ionophore and phorbol ester.
Topics: Animals; Calcimycin; Cell Line; Dose-Response Relationship, Immunologic; Humans; Hybridomas; Interleukin-1; Interleukin-2; Leukemia P388; Lymphocyte Activation; Lymphoma; Mice; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Acetylcholine release from guinea pig caudate slices evoked by phorbol ester and calcium.
Topics: Acetylcholine; Aminoquinolines; Animals; Calcimycin; Calcium; Caudate Nucleus; Drug Synergism; Female; Guinea Pigs; In Vitro Techniques; Male; Phorbols; Polymyxin B; Tetradecanoylphorbol Acetate | 1986 |
Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts.
Topics: Animals; Calcimycin; Calcium; Cell Line; Diglycerides; Enzyme Activation; Ethers; Fibroblast Growth Factors; Fibroblasts; Gene Expression Regulation; Ionomycin; Mice; Oncogenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Aggregation of marine sponge cells induced by Ca pulses, Ca ionophores, and phorbol esters proceeds in the absence of external Ca.
Topics: Animals; Calcimycin; Calcium; Cell Adhesion Molecules; Cell Aggregation; Ionophores; Phorbol Esters; Porifera; Proteins; Tetradecanoylphorbol Acetate | 1986 |
Generation of the arachidonic acid metabolite 8-HETE by extracts of mouse skin treated with phorbol ester in vivo; identification by 1H-n.m.r. and GC-MS spectroscopy.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Magnetic Resonance Spectroscopy; Mice; Phorbol Esters; Skin; Tetradecanoylphorbol Acetate | 1986 |
Protein kinase C activators and calcium-mobilizing agents synergistically increase GH, LH, and TSH secretion from anterior pituitary cells.
Topics: Animals; Calcimycin; Calcium; Diglycerides; Drug Synergism; Female; Glycerides; Marine Toxins; Oxocins; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1986 |
Effects of a phorbol ester and diacylglycerols on secretion of mucin and arginine esterase by rat submandibular gland cells.
Topics: Animals; Calcimycin; Calcium; Carboxylic Ester Hydrolases; Diglycerides; Fluphenazine; Glycerides; Male; Mucins; Phorbols; Polymyxin B; Rats; Rats, Inbred Strains; Submandibular Gland; Tetradecanoylphorbol Acetate | 1986 |
Early precursor thymocytes can produce interleukin 2 upon stimulation with calcium ionophore and phorbol ester.
Topics: Animals; Antibodies, Monoclonal; Antigens, Ly; Calcimycin; Cell Differentiation; Concanavalin A; Flow Cytometry; Hematopoietic Stem Cells; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1986 |
A defect of platelet release reaction in a patient with SLE: impaired platelet aggregation induced by phorbol ester with a normal phosphorylation of 40K protein.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Proteins; Calcimycin; Collagen; Diglycerides; Epinephrine; Female; Humans; Lupus Erythematosus, Systemic; Phorbols; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombin | 1986 |
Calcium regulation of tissue plasminogen activator and prostaglandin biosynthesis in HeLa cells.
Topics: Calcimycin; Calcium; Dinoprostone; HeLa Cells; Humans; Kinetics; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator | 1986 |
Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells.
Topics: Animals; Calcimycin; Calcium; Carbachol; Cell Line; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Kinetics; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidylserines; Protein Kinase C; Quinuclidinyl Benzilate; Receptors, Cholinergic; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Is a rise in intracellular concentration of free calcium necessary or sufficient for stimulated cytoskeletal-associated actin?
Topics: Actins; Aminoquinolines; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cytoskeletal Proteins; Cytoskeleton; Fluorescent Dyes; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Tetradecanoylphorbol Acetate | 1986 |
Mechanism of phorbol ester activation of calcium-activated, phospholipid-dependent protein kinase.
Topics: Animals; Caenorhabditis elegans Proteins; Calcimycin; Carrier Proteins; Concanavalin A; Dexamethasone; Enzyme Activation; Female; Kinetics; Lipopolysaccharides; Lymphocytes; Melitten; Mice; Phorbol Esters; Phospholipases A; Phytohemagglutinins; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Spleen; Tetradecanoylphorbol Acetate; Tretinoin; Type C Phospholipases | 1986 |
Enhancement of collagen-degrading enzymes in the dermis after one topical application of tumor-promoting phorbol esters.
Topics: Administration, Topical; Animals; Calcimycin; Collagen; Epidermis; Female; Mice; Phorbol Esters; Tetradecanoylphorbol Acetate | 1986 |
Interleukin 1 production by human polymorphonuclear neutrophils.
Topics: Calcimycin; Cell Cycle; Cell Separation; Cells, Cultured; Cytochalasin B; Dialysis; Endopeptidases; Fibroblasts; Hot Temperature; Humans; Hydrogen-Ion Concentration; Interleukin-1; Lipopolysaccharides; Lymphocyte Activation; Molecular Weight; Monocytes; Neprilysin; Neutrophils; Protease Inhibitors; Synovial Fluid; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Phorbol esters stimulate phosphate accumulation synergistically with A23187 in cultured renal tubular cells.
Topics: Animals; Calcimycin; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Isomerism; Kidney Tubules; Mice; Phorbol Esters; Phosphates; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Differential mechanisms of translocation of protein kinase C to plasma membranes in activated human neutrophils.
Topics: Biological Transport, Active; Calcimycin; Calcium; Cell Membrane; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Effect of protein kinase C activation and Ca2+ mobilization on hexose transport in Swiss 3T3 cells.
Topics: 3-O-Methylglucose; Animals; Biological Transport, Active; Calcimycin; Calcium; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; Insulin; Kinetics; Methylglucosides; Methylglycosides; Mice; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Potentiation and inhibition of secretion from neutrophils by phorbol ester.
Topics: Animals; Calcimycin; Calcium; Cytoplasmic Granules; Exocytosis; Glucuronidase; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbols; Phosphatidic Acids; Phosphoproteins; Phosphorylation; Rabbits; Tetradecanoylphorbol Acetate | 1986 |
Calcium ionophore A 23 187 in the presence of phorbol ester PMA: a potent inducer of interleukin 2 and interferon-gamma synthesis by human blood cells.
Topics: Calcimycin; Calcium; Cells, Cultured; Humans; Interferon-gamma; Interleukin-2; Kinetics; Manganese; Monocytes; Phorbols; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
Possible involvement of phosphorylation of a 36,000-dalton protein of rat basophilic leukemia (RBL-2H3) cell membranes in serotonin release.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Basophils; Calcimycin; Cell Membrane; Diglycerides; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Isoquinolines; Leukemia, Experimental; Molecular Weight; Phosphoproteins; Phosphorylation; Piperazines; Rats; Serotonin; Tetradecanoylphorbol Acetate | 1986 |
Selective regulation of trypsin gene expression by calcium and by glucose starvation in a rat exocrine pancreas cell line.
Topics: Acetyltransferases; Animals; Calcimycin; Calcium; Cell Line; Chloramphenicol O-Acetyltransferase; Drug Synergism; Enhancer Elements, Genetic; Gene Expression Regulation; Glucose; Nucleotides, Cyclic; Pancreas; Promoter Regions, Genetic; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Trypsin | 1986 |
Phorbol myristate acetate inhibits anti-IgM-mediated signaling in resting B cells.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcimycin; Calcium; Cell Membrane; Female; Immunoglobulin D; Immunoglobulin M; Lymphocyte Activation; Mice; Phorbols; Phosphatidylinositols; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Induction of mouse epidermal ornithine decarboxylase by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate: dependence on calcium availability.
Topics: Animals; Autoradiography; Calcimycin; Calcium; Chemical Precipitation; Densitometry; Eflornithine; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Female; Mice; Nucleic Acid Hybridization; Ornithine; Ornithine Decarboxylase; Phorbols; Protein Binding; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate | 1986 |
c-fos and c-myc gene activation, ionic signals, and DNA synthesis in thymocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Calcium; Cell Division; Concanavalin A; DNA Replication; Egtazic Acid; Mice; Mice, Inbred BALB C; Oncogenes; Osmolar Concentration; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymus Gland | 1986 |
Development of a neural phenotype in differentiating ganglion cell-derived human neuroblastoma cells.
Topics: Acetylcholine; Atropine; Calcimycin; Calcium; Cell Differentiation; Clone Cells; Ganglia, Sympathetic; Humans; Membrane Potentials; Muscarine; Neuroblastoma; Norepinephrine; Phenotype; Potassium; Receptors, Muscarinic; Rubidium; Tetradecanoylphorbol Acetate | 1986 |
Lipoxygenation of arachidonic acid by differentiated and undifferentiated human promyelocytic HL-60 cells.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Differentiation; Cell Line; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Lipoxygenase; Tetradecanoylphorbol Acetate | 1986 |
Role of extracellular calcium in neutrophil responsiveness to chemotactic tripeptides.
Topics: Calcimycin; Calcium; Extracellular Space; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of canine platelet aggregation by barbiturates.
Topics: Adenosine Diphosphate; Animals; Barbital; Barbiturates; Blood Platelets; Calcimycin; Calcium; Collagen; Dogs; Pentobarbital; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thiamylal; Type C Phospholipases | 1986 |
Release of cytoprotective PGE2 from cultured macrophages induced by antacids and sucralfate.
Topics: Aluminum; Aluminum Hydroxide; Animals; Antacids; Anti-Ulcer Agents; Calcimycin; Cells, Cultured; Dimethyl Sulfoxide; Dinoprostone; Macrophages; Male; Mice; Mice, Inbred Strains; Prostaglandins E; Sucralfate; Tetradecanoylphorbol Acetate | 1986 |
Eicosanoid synthesis by cultured human urothelial cells: potential role in bladder cancer.
Topics: Arachidonic Acids; Bradykinin; Calcimycin; Carcinogens; Dinoprostone; Epinephrine; Epithelium; Humans; Prostaglandins E; Tetradecanoylphorbol Acetate; Thrombin; Ureter; Urinary Bladder Neoplasms | 1986 |
1,25-Dihydroxyvitamin D3-regulated expression of genes involved in human T-lymphocyte proliferation and differentiation.
Topics: Calcimycin; Calcitriol; Cell Differentiation; DNA-Binding Proteins; Gene Expression Regulation; Humans; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Lymphokines; Proto-Oncogene Proteins; Receptors, Immunologic; Receptors, Interleukin-2; Secretory Rate; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Regulation of B-lymphocyte activation, proliferation, and immunoglobulin secretion.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcimycin; Cell Division; Ethers; Growth Substances; Immunoglobulin M; Immunoglobulins; Interleukin-4; Ionomycin; Lymphocyte Activation; Lymphokines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Ca2+ and phorbol ester synergistically induce HL-60 differentiation.
Topics: Antigens, Surface; Calcimycin; Calcium; Cell Differentiation; Cell Line; Drug Synergism; Granulocytes; Humans; Leukemia, Myeloid; Macrophages; Monocytes; Tetradecanoylphorbol Acetate | 1986 |
Synergistic induction by calcium ionophore and phorbol ester of interleukin-2 (IL-2) receptor expression, IL-2 production, and proliferation in autoimmune MRL/MP-lpr mice.
Topics: Aging; Animals; Calcimycin; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Flow Cytometry; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred Strains; Mitosis; Receptors, Immunologic; Receptors, Interleukin-2; Spleen; Tetradecanoylphorbol Acetate | 1986 |
Prolactin stimulation of ornithine decarboxylase and mitogenesis in Nb2 node lymphoma cells: the role of protein kinase C and calcium mobilization.
Topics: Animals; Calcimycin; Calcium; Cell Division; Cell Line; DNA Replication; Enzyme Induction; Lymphoma; Ornithine Decarboxylase; Phorbol Esters; Prolactin; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1986 |
BSF-1 action on resting B cells does not require elevation of inositol phospholipid metabolism or increased [Ca2+]i.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcimycin; Calcium; DNA Replication; Female; Growth Substances; Histocompatibility Antigens Class II; Interleukin-4; Interphase; Lymphokines; Mice; Mice, Inbred BALB C; Phosphatidylinositols; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate | 1986 |
Role of protein kinase C and intracellular calcium mobilization in the induction of macrophage tumoricidal activity by interferon-gamma.
Topics: Aminoquinolines; Calcimycin; Calcium; Cytotoxicity, Immunologic; Imidazoles; Interferon-gamma; Macrophage Activation; Macrophages; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate; Trifluoperazine | 1986 |
Lack of correlation between TPA-induced prostaglandin biosynthesis and ornithine decarboxylase activity in Balb/c mouse 3T3 fibroblasts.
Topics: Calcimycin; Cell Division; Cells, Cultured; Fibroblasts; Indomethacin; Ornithine Decarboxylase; Prostaglandins; Tetradecanoylphorbol Acetate | 1986 |
Modulation of c-fos and c-myc mRNA levels in normal human lymphocytes by calcium ionophore A23187 and phorbol ester.
Topics: Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Calcimycin; Egtazic Acid; Humans; Lymphocyte Activation; Lymphocytes; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate | 1986 |
Regulation of class II gene expression: analysis in B cell stimulatory factor 1-inducible murine pre-B cell lines.
Topics: Animals; B-Lymphocytes; Calcimycin; Cell Line; Cycloheximide; Dinoprostone; Gene Expression Regulation; Growth Substances; Histocompatibility Antigens Class II; Interleukin-4; Lymphokines; Mice; Prostaglandins E; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic | 1986 |
Phorbol diester synergistically stimulates agonist-induced lipoxygenase product formation in murine macrophages.
Topics: Animals; Arachidonate Lipoxygenases; Calcimycin; Drug Synergism; Enzyme Activation; Female; In Vitro Techniques; Macrophages; Mice; Tetradecanoylphorbol Acetate | 1986 |
[Stimulation of human lymphocytes by phorbol acetate and a calcium ionophore induces an early transient expression of the c-fos oncogene followed by c-myc].
Topics: Calcimycin; Gene Expression Regulation; Humans; Lymphocyte Activation; Oncogenes; Proto-Oncogene Mas; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Possible involvement of a lanthanide-sensitive protein kinase C substrate in lanthanide promotion of neoplastic transformation.
Topics: Calcimycin; Calcium Channel Blockers; Cell Line; Cell Transformation, Neoplastic; Enzyme Activation; ErbB Receptors; Metals, Rare Earth; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Analysis of isolated and combined effects of calcium ionophore and phorbol ester on T lymphocyte activation.
Topics: Animals; Calcimycin; Drug Synergism; Female; Interleukin-2; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1986 |
Mechanisms of action of gonadotropin releasing hormone on rat granulosa cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Female; Gonadotropin-Releasing Hormone; Granulosa Cells; In Vitro Techniques; Progesterone; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Tetradecanoylphorbol Acetate | 1986 |
Mitogenic effect of PMA + IL 2 on subpopulations of corticoresistant thymocytes.
Topics: Animals; Antigen-Presenting Cells; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Calcimycin; Drug Resistance; Female; Hydrocortisone; Interleukin-2; Lymphocyte Activation; Male; Mice; Mitogens; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1986 |
Interleukin 2 induction of interferon-gamma mRNA synthesis.
Topics: Animals; Calcimycin; Cell Line; Cell Membrane; Cytosol; Diglycerides; Enzyme Activation; Interferon-gamma; Interleukin-2; Mice; Protein Kinase C; RNA, Messenger; Stimulation, Chemical; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1986 |
Interleukin 2 responses of lpr and normal L3T4-/Lyt-2- T cells induced by TPA plus A23187.
Topics: Animals; Autoimmune Diseases; Calcimycin; Interleukin-2; Lymphocyte Activation; Mice; Mice, Mutant Strains; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1987 |
Prolactin-dependent mitogenesis in Nb 2 node lymphoma cells: effects of immunosuppressive cyclopeptides.
Topics: Animals; Calcimycin; Cell Division; Cyclosporins; Depsipeptides; DNA; Enzyme Induction; Estradiol; Gossypol; Indomethacin; Lymphoma; Male; Masoprocol; Ornithine Decarboxylase; Peptides, Cyclic; Prolactin; Quercetin; Quinacrine; Rats; Receptors, Prolactin; Tetradecanoylphorbol Acetate | 1987 |
Induction of lymphokine synthesis in peripheral blood mononuclear cells with phorbol ester and calcium ionophore allows precise measurement of individual variations in capacity to produce IL 2.
Topics: Calcimycin; Hodgkin Disease; Humans; In Vitro Techniques; Interleukin-2; Leukocytes; Lymphokines; Phytohemagglutinins; Reference Values; Tetradecanoylphorbol Acetate | 1986 |
The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations.
Topics: Blood Platelets; Calcimycin; Calcium; Cytoplasm; Diltiazem; Humans; Kinetics; Molecular Weight; Nimodipine; Phosphoproteins; Plant Extracts; Platelet Aggregation; Serotonin; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Verapamil | 1987 |
Calcium and protein kinase C inhibit biosynthesis of Aplysia egg-laying hormone.
Topics: Animals; Aplysia; Calcimycin; Calcium; Invertebrate Hormones; Neurons; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Protamine sulfate-induced enzyme secretion from rabbit neutrophils.
Topics: Animals; Calcimycin; Exocytosis; In Vitro Techniques; Kinetics; L-Lactate Dehydrogenase; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neuraminidase; Neutrophils; Protamines; Rabbits; Tetradecanoylphorbol Acetate | 1986 |
The effects of phorbol ester on alloantigen presentation.
Topics: Animals; Antigen-Presenting Cells; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; B-Lymphocytes; Calcimycin; Histocompatibility Antigens Class II; In Vitro Techniques; Lymphocyte Activation; Mice; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thyroid Gland | 1987 |
The cellular basis of the calcium dependence of GnRH-stimulated gonadotropin release from frog, Rana pipiens, pituitaries.
Topics: Animals; Benzimidazoles; Calcimycin; Calcium; Colchicine; Colforsin; Cytochalasin B; Cytoskeleton; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Nocodazole; Pimozide; Pituitary Gland; Rana pipiens; Secretory Rate; Tetradecanoylphorbol Acetate; Time Factors; Trifluoperazine | 1986 |
A phorbol ester has dual actions on the mechanical response in the rabbit mesenteric and porcine coronary arteries.
Topics: Animals; Calcimycin; Calcium; In Vitro Techniques; Muscle, Smooth, Vascular; Phosphatidylserines; Potassium; Rabbits; Swine; Tetradecanoylphorbol Acetate; Time Factors; Vasoconstriction | 1986 |
Induction of human interferon-gamma mRNA analyzed by cytoplasmic dot hybridization: effect of Con A, TPA, and A23187.
Topics: Calcimycin; Cell Line; Concanavalin A; Gene Expression Regulation; Humans; Interferon-gamma; Nucleic Acid Hybridization; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1986 |
Mechanism of hepatic glycogen synthase inactivation induced by Ca2+-mobilizing hormones. Studies using phospholipase C and phorbol myristate acetate.
Topics: Animals; Arginine Vasopressin; Calcimycin; Calcium; Diglycerides; Glycogen Synthase; In Vitro Techniques; Liver; Male; Phosphorylases; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1986 |
Temporal patterns of protein phosphorylation after angiotensin II, A23187 and/or 12-O-tetradecanoylphorbol 13-acetate in adrenal glomerulosa cells.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Autoradiography; Calcimycin; Cattle; Electrophoresis; Nitrendipine; Phosphorylation; Proteins; Saralasin; Tetradecanoylphorbol Acetate | 1986 |
Skin tumor promotion is associated with increased type V collagen content in the dermis.
Topics: Animals; Calcimycin; Cell Transformation, Neoplastic; Collagen; Epidermis; Female; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Luteinizing hormone release from chicken pituitary cells: synergism between calcium and protein kinase C and its inhibition by calmodulin antagonists.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Chickens; Chlorpromazine; Drug Synergism; Egtazic Acid; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Pituitary Gland, Anterior; Potassium; Protein Kinase C; Pyrrolidonecarboxylic Acid; Tetradecanoylphorbol Acetate; Trifluoperazine | 1987 |
Modulation of arachidonic acid metabolism in a cultured newborn rat keratinocyte cell line.
Topics: Animals; Animals, Newborn; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cell Line; Dexamethasone; Diglycerides; Epidermal Growth Factor; Melitten; Prostaglandin-Endoperoxide Synthases; Rats; Skin; Tetradecanoylphorbol Acetate | 1987 |
The effects of A23187 and phorbol ester on the phosphorylation of proteins in rat anterior pituitary cells.
Topics: Animals; Calcimycin; Cells, Cultured; Male; Phosphorylation; Pituitary Gland, Anterior; Protein Kinase C; Proteins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Carbachol regulates cholecystokinin receptor on pancreatic acinar cells.
Topics: Animals; Atropine; Binding, Competitive; Calcimycin; Calcium; Carbachol; Kinetics; Male; Pancreas; Rats; Rats, Inbred Strains; Receptors, Cholecystokinin; Tetradecanoylphorbol Acetate | 1987 |
Direct induction of lymphocyte killing by calcium ionophore and phorbol ester treatment.
Topics: Antibody-Dependent Cell Cytotoxicity; Calcimycin; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Kinetics; Lymphocytes; Phenotype; Tetradecanoylphorbol Acetate | 1987 |
Production of lymphotoxin and tumour necrosis factor by a T-cell hybridoma.
Topics: Antibody Specificity; Calcimycin; Concanavalin A; Glycoproteins; Growth Inhibitors; Humans; Hybridomas; Immune Sera; Lymphotoxin-alpha; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1987 |
sn-1,2-Diacylglycerols and phorbol diesters stimulate thromboxane synthesis by de novo synthesis of prostaglandin H synthase in human promyelocytic leukemia cells.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Differentiation; Cell Line; Diglycerides; Glycerides; Humans; Kinetics; Leukemia, Myeloid; Macrophages; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane B2; Trifluoperazine | 1987 |
A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor.
Topics: Antibodies, Monoclonal; Base Composition; Base Sequence; Calcimycin; Cell Line; DNA, Recombinant; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; Interleukin-2; Lymphocyte Activation; Phytohemagglutinins; Plasmids; Promoter Regions, Genetic; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transfection | 1987 |
The role of class I histocompatibility antigens in the regulation of T-cell activation.
Topics: Antibodies; Blood Cells; Calcimycin; Cell Adhesion; Cell Division; Histocompatibility Antigens; Humans; Interleukin-2; Lymphocyte Activation; Receptors, Immunologic; Receptors, Interleukin-2; Receptors, Transferrin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Antigen-receptor interaction requirement for conjugate formation and lethal-hit triggering by cytotoxic T lymphocytes can be bypassed by protein kinase C activators and Ca2+ ionophores.
Topics: Animals; Calcimycin; Calcium; Cell Line; Cytotoxicity, Immunologic; Edetic Acid; Egtazic Acid; Enzyme Activation; Ethers; Ionomycin; Kinetics; Mice; Mice, Inbred BALB C; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1987 |
Chronic 12-O-tetradecanoylphorbol-13-acetate treatment prevents restoration of collagen loss associated with its inflammatory effect on mouse skin.
Topics: Animals; Calcimycin; Collagen; Female; Mice; Phorbol Esters; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Activation of protein kinase C is coupled to prostaglandin F2 alpha synthesis in the ovary: studies in cultured swine granulosa cells.
Topics: Animals; Calcimycin; Cells, Cultured; Diglycerides; Dinoprost; Enzyme Activation; Female; Granulosa Cells; Indomethacin; Prostaglandins F; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Signals for activation and proliferation of murine T lymphocyte clones.
Topics: Animals; Calcimycin; Calcium; Clone Cells; DNA; Enzyme Activation; Interleukin-2; Lymphocyte Activation; Mice; Protein Kinase C; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Phorbol esters reduce gonadotrope responsiveness to protein kinase C activators but not to Ca2+-mobilizing secretagogues. Does protein kinase C mediate gonadotropin-releasing hormone action?
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Female; Gonadotropin-Releasing Hormone; Inositol Phosphates; Luteinizing Hormone; Octoxynol; Phorbol Esters; Pituitary Gland; Pituitary Hormone-Releasing Hormones; Polyethylene Glycols; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Evidence of protein kinase C involvement in phorbol diester-stimulated arachidonic acid release and prostaglandin synthesis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Indomethacin; Isoquinolines; Kidney; Lysophosphatidylcholines; Molecular Weight; Phospholipid Ethers; Phosphorylation; Piperazines; Prostaglandins; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Luteinizing hormone-releasing hormone (LHRH)-induced arachidonic acid release in rat granulosa cells. Role of calcium and protein kinase C.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Female; Gonadotropin-Releasing Hormone; Granulosa Cells; In Vitro Techniques; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1987 |
Restoration of lipopolysaccharide-mediated cytotoxic macrophage induction in C3H/HeJ mice by interferon-gamma or a calcium ionophore.
Topics: Animals; Calcimycin; Calcium; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Neoplasms, Experimental; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1987 |
Calcium ionophore, phorbol ester, and chemotactic peptide-induced cytoskeleton reorganization in human neutrophils.
Topics: Actins; Calcimycin; Calcium; Cytoskeleton; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Polymers; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
A novel synthetic vitamin A-like compound (a polyprenoic acid derivative, E-5166) inhibits the release of arachidonic acid stimulated by epidermal growth factor.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Epidermal Growth Factor; Phosphatidylinositols; Skin; Stimulation, Chemical; Swine; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1987 |
Interleukin-2 responses of MRL/lpr mouse splenocytes and lymph node cells induced by TPA and A23187.
Topics: Animals; Autoimmune Diseases; Calcimycin; Calcium; Calcium Channel Blockers; Dactinomycin; Egtazic Acid; Interleukin-2; Lymph Nodes; Lymphocyte Activation; Lymphocytes; Mice; Mice, Mutant Strains; Mitomycin; Mitomycins; Receptors, Immunologic; Receptors, Interleukin-2; Spleen; Tetradecanoylphorbol Acetate | 1987 |
The effect of LPS on expression of the early "competence" genes JE and KC in murine peritoneal macrophages.
Topics: Animals; Calcimycin; Calcium; Gene Expression Regulation; Genes; Growth Substances; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Peritoneal Cavity; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1987 |
Effects of the phorbolester TPA and of the ionophore A 23187 on phospholipase A2 and C activities in the mouse epidermal cell line HEL-30.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Carcinogens; Cell Line; Dinoprostone; Enzyme Activation; Epidermis; Mice; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Prostaglandins E; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
Measurement of synergistic effects of protein kinase C activators and calcium ionophore in pituitary cell cultures.
Topics: Animals; Calcimycin; Cells, Cultured; Diglycerides; Drug Synergism; Enzyme Activation; Female; Kinetics; Luteinizing Hormone; Pituitary Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Stimulation of histamine synthesis from tumour cells by concanavalin A and A23187.
Topics: Animals; Calcimycin; Cell Line; Concanavalin A; Histamine; Mice; Neoplasms, Experimental; Tetradecanoylphorbol Acetate | 1987 |
The lack of PDGE-stimulated PGE2 release from ras-transformed NIH-3T3 cells results from reduced phospholipase C but not phospholipase A2 activity.
Topics: Animals; Calcimycin; Cell Transformation, Neoplastic; Cells, Cultured; Dinoprostone; Kinetics; Mice; Mice, Inbred Strains; Oncogenes; Phospholipases; Phospholipases A; Phospholipases A2; Platelet-Derived Growth Factor; Prostaglandins E; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
Phosphorylation and dephosphorylation of soluble proteins in human eosinophils.
Topics: Blood Proteins; Calcimycin; Eosinophils; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Solubility; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Induction of responsiveness to interleukin 2 in mouse lymphocytes by synergistic action of ionophore A 23187 and diacylglycerol.
Topics: Animals; Calcimycin; Calcium; Diglycerides; Drug Synergism; Glycerides; Interleukin-2; Lymphocyte Activation; Manganese; Mice; Mice, Inbred C57BL; Receptors, Immunologic; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate | 1987 |
Up and down regulation of serine esterase release from mouse cytotoxic T lymphocytes by tumor-promoting phorbol ester.
Topics: Animals; Calcimycin; Cells, Cultured; Esterases; Kinetics; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Protein Kinase C; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1987 |
The induction of IFN-gamma production and m-RNAs of interleukin 2 and IFN-gamma by phorbol esters and a calcium ionophore.
Topics: Calcimycin; Carcinogens; Cell Line; Cycloheximide; Diterpenes; Enterotoxins; Humans; Interferon-gamma; Interleukin-2; Protein Biosynthesis; RNA, Messenger; Staphylococcus aureus; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Role of protein kinase C in luteinizing hormone-releasing hormone (LHRH)-stimulated progesterone production in rat granulosa cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Female; Gonadotropin-Releasing Hormone; Granulosa Cells; In Vitro Techniques; Isoquinolines; Kinetics; Phorbol Esters; Piperazines; Progesterone; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
[Effects of benzydamine on leukocyte aggregation].
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzydamine; Calcimycin; Cell Aggregation; Cell Survival; Exudates and Transudates; In Vitro Techniques; Leukocytes; Male; N-Formylmethionine Leucyl-Phenylalanine; Phagocytes; Pyrazoles; Rats; Tetradecanoylphorbol Acetate | 1987 |
Abnormal stimulated adherence of neonatal granulocytes: impaired induction of surface Mac-1 by chemotactic factors or secretagogues.
Topics: Antigens, Surface; Blood Proteins; Calcimycin; Cell Adhesion; Chemotactic Factors; Glycoproteins; Granulocytes; Humans; Infant, Newborn; Lactoferrin; Lymphocyte Function-Associated Antigen-1; Macrophage-1 Antigen; Receptors, Formyl Peptide; Receptors, Immunologic; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1987 |
Calcium ion influx during mitogenic stimulation of lymphocytes.
Topics: Biological Transport, Active; Calcimycin; Calcium Chloride; Cells, Cultured; Child; Child, Preschool; Cytosol; Humans; Interleukin-2; Kinetics; Lymphocyte Activation; Lymphocytes; Palatine Tonsil; Receptors, Immunologic; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate | 1987 |
Disparate effects of activators of protein kinase C on HL-60 promyelocytic leukemia cell differentiation.
Topics: Calcimycin; Cell Differentiation; Cell Line; Diglycerides; Diterpenes; Enzyme Activation; Humans; Leukemia, Myeloid, Acute; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Effects of phorbol esters, A23187 and vasopressin on oleate metabolism in isolated rat hepatocytes.
Topics: Animals; Arginine Vasopressin; Calcimycin; Cells, Cultured; Glucose; Glycolysis; Ketone Bodies; Kinetics; Liver; Male; Oleic Acid; Oleic Acids; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Stimulation and inhibition of elastase release from human neutrophil-dependence on the calcium messenger system.
Topics: Adult; Calcimycin; Calcium; Edetic Acid; Enzyme Activation; Humans; Male; Neutrophils; Pancreatic Elastase; Protein Kinase C; Tetradecanoylphorbol Acetate; Trifluoperazine; Verapamil | 1987 |
Inhibitory effect of the intrauterine infusion of phorbol 12-myristate 13-acetate and 1-oleoyl-2-acetylglycerol on the decidual cell reaction in rats.
Topics: Animals; Calcimycin; Calcium; Decidua; Diglycerides; Enzyme Activation; Female; Glycerides; Indomethacin; Prostaglandins; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Histamine acts directly on human T cells to inhibit interleukin-2 and interferon-gamma production.
Topics: Antigen-Presenting Cells; Calcimycin; Cells, Cultured; Depression, Chemical; DNA Replication; Enterotoxins; Histamine; Humans; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Regulation of interleukin 2 and interleukin 2 receptor gene expression in human T cells: I. Effect of Ca2+-ionophore on phorbol myristate acetate co-stimulated cells.
Topics: Calcimycin; Cell Division; Drug Synergism; Gene Expression Regulation; Humans; Interleukin-2; Lymphocyte Activation; Receptors, Immunologic; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Phorbol esters and calcium ionophores inhibit internalization and accelerate recycling of receptors in macrophages.
Topics: Animals; Calcimycin; Cell Line; Kinetics; Macrophages; Mice; Receptors, Drug; Tetradecanoylphorbol Acetate | 1987 |
Phosphorylation of the CD8 antigen on cytotoxic human T cells in response to phorbol myristate acetate or antigen-presenting B cells.
Topics: Antibodies, Monoclonal; Antigen-Presenting Cells; Antigens, Differentiation, T-Lymphocyte; B-Lymphocytes; Calcimycin; Cell Line; Cytotoxicity, Immunologic; Humans; Phosphoproteins; Phosphorylation; Phytohemagglutinins; Protein Processing, Post-Translational; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1987 |
Calcium ionophore A23187 does not stimulate lipopolysaccharide nonresponsive C3H/HeJ peritoneal macrophages to produce interleukin 1.
Topics: Animals; Calcimycin; Calcium; Calmodulin; Cells, Cultured; Cytoplasm; Extracellular Space; Interleukin-1; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Tetradecanoylphorbol Acetate | 1987 |
The expression and regulation of c-myb transcription in B6/lpr Lyt-2-, L3T4-T lymphocytes.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Gene Expression Regulation; Interleukin-2; Lupus Erythematosus, Systemic; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Mutant Strains; Proto-Oncogene Proteins; Proto-Oncogenes; Receptors, Immunologic; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Large scale production and purification of human IL-2 from buffy coat lymphocytes stimulated with 12-O-tetradecanoylphorbol 13-acetate and calcium ionophore A23187.
Topics: Calcimycin; Cell Separation; Cells, Cultured; Chromatography, High Pressure Liquid; Drug Synergism; Humans; Interleukin-2; Lymphocyte Activation; Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Synergistic action of calcium ionophore A23187 and phorbol ester TPA on B-chronic lymphocytic leukemia cells.
Topics: Antibody Formation; B-Lymphocytes; Calcimycin; Cells, Cultured; DNA Replication; Drug Synergism; Humans; Leukemia, Hairy Cell; Leukemia, Lymphoid; Lymphocyte Activation; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1987 |
Identification, isolation, and characterization of a novel cytotoxin in murine cytolytic lymphocytes.
Topics: Animals; Antibodies; Calcimycin; Cell Line; Cell Survival; Cytotoxins; DNA; Fluorescent Antibody Technique; Mice; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1987 |
Tumor-promoting phorbol esters cause a stable reduction of dermal collagen in mouse skin.
Topics: Animals; Calcimycin; Cell Division; Collagen; Female; Fluocinolone Acetonide; Mice; Phorbol Esters; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1987 |
Phenotypic and functional analysis of human CD3+ and CD3- clones with "lymphokine-activated killer" (LAK) activity. Frequent occurrence of CD3+ LAK clones which produce interleukin-2.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcimycin; Cell Line; Clone Cells; Humans; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Lymphokines; Phenotype; Rosette Formation; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1987 |
Platelet-derived growth factor-inducible genes respond differentially to at least two distinct intracellular second messengers.
Topics: Animals; Calcimycin; Cells, Cultured; Clone Cells; Genes; Humans; Kinetics; Mice; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Interleukin secretion by B cell lines and splenic B cells stimulated with calcium ionophore and phorbol ester.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcimycin; Cell Line; Dose-Response Relationship, Drug; In Vitro Techniques; Interleukin-2; Interleukin-4; Interleukins; Mice; Receptors, Immunologic; Spleen; Tetradecanoylphorbol Acetate | 1987 |
Correction in vitro of lymphocyte activation defect in autoimmune mice.
Topics: Aging; Animals; Autoimmune Diseases; Calcimycin; Concanavalin A; DNA; Gene Expression Regulation; Interleukin-2; Lymphocyte Activation; Male; Mice; Proto-Oncogenes; Receptors, Immunologic; Receptors, Interleukin-2; Tetradecanoylphorbol Acetate | 1987 |
Induction of IL-2 and lymphokine activated killer cells in the cat.
Topics: Animals; Calcimycin; Cats; Concanavalin A; Cytotoxicity, Immunologic; Interleukin-2; Killer Cells, Natural; Lymphokines; Tetradecanoylphorbol Acetate | 1987 |
The effects of phorbol ester and Ca ionophore on c-fos and c-myc expression and on DNA synthesis in human lymphocytes are not directly related.
Topics: Adult; Calcimycin; Cells, Cultured; DNA Replication; Humans; Kinetics; Lymphocytes; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1987 |
Phorbol ester stimulation of prostanoid synthesis by cultured astrocytes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Astrocytes; Calcimycin; Calcium; Cells, Cultured; Cerebral Cortex; Prostaglandins; Protein Kinase C; Quinacrine; Rats; Tetradecanoylphorbol Acetate | 1987 |
Phorbol ester stimulates calcium sequestration in saponized human platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Diphosphate; Alprostadil; Benzofurans; Biological Transport, Active; Blood Platelets; Calcimycin; Calcium; Calcium Radioisotopes; Chelating Agents; Fura-2; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Kinetics; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin | 1987 |
c-fos sequence necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate and the calcium ionophore.
Topics: Calcimycin; Calcium; DNA Mutational Analysis; DNA-Binding Proteins; Enhancer Elements, Genetic; Epidermal Growth Factor; Gene Expression Regulation; Humans; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogenes; Regulatory Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1987 |
[Possibility of identifying tumor promoters by their inhibitory action on the intercellular exchange of lucifer yellow].
Topics: Animals; Anthralin; Butylated Hydroxytoluene; Calcimycin; Carcinogens; Cell Line; Cricetinae; DDT; Diterpenes; Fluorescent Dyes; In Vitro Techniques; Isoquinolines; Phenobarbital; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Mitogenic action of phorbol ester TPA and calcium ionophore A23187 on human cord and maternal/adult peripheral lymphocytes: regulation by prostaglandin E2.
Topics: Adult; Calcimycin; Cell Division; Dinoprostone; Drug Interactions; Female; Fetal Blood; Humans; Indomethacin; Infant, Newborn; Lymphocyte Activation; Lymphocytes; Pregnancy; Prostaglandins E; Tetradecanoylphorbol Acetate | 1987 |
Epidermal growth factor (EGF), tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA) and calcium ionophore A23187 increase cytoplasmic free calcium and stimulate arachidonic acid release and PGE2/6-keto PGF1 alpha production in cultured porcine thyroi
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Calcimycin; Calcium; Cells, Cultured; Cytoplasm; Dinoprostone; Epidermal Growth Factor; Fluorescent Dyes; Fura-2; Kinetics; Prostaglandins; Prostaglandins E; Spectrometry, Fluorescence; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland | 1987 |
Interferon-gamma is produced by activated immature mouse thymocytes and inhibits the interleukin 4-induced proliferation of immature thymocytes.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Cell Division; Cells, Cultured; Female; Indomethacin; Interferon-gamma; Interleukin-4; Interleukins; Lymphocyte Activation; Mice; Mice, Inbred BALB C; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1987 |
Role for protein kinase C in A23187 induced glomerular arachidonate release and PGE2 production.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; Female; Kidney Glomerulus; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Posttranslational modification of interleukin-2 is a late event during activation of human T lymphocytes by ionophore A23187 and phorbol ester.
Topics: Calcimycin; Electrophoresis, Polyacrylamide Gel; Glycosylation; Humans; Immunoenzyme Techniques; Interleukin-2; Kinetics; Lymphocyte Activation; N-Acetylneuraminic Acid; Protein Processing, Post-Translational; Sialic Acids; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transferases | 1988 |
The effect of apomorphine on exocytosis and metabolic burst of polymorphonuclear leukocytes.
Topics: Adenosine Triphosphate; Animals; Apomorphine; Calcimycin; Exocytosis; In Vitro Techniques; L-Lactate Dehydrogenase; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitroblue Tetrazolium; Rabbits; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate | 1987 |
Leukotriene production by cultured astroglial cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Calcimycin; Carcinogens; Cells, Cultured; Kinetics; Phorbol Esters; Pyrazoles; Rats; SRS-A; Tetradecanoylphorbol Acetate | 1987 |
Impaired phorbol ester and calcium ionophore induced proliferation of T cells from old humans.
Topics: Adult; Aged; Aging; Calcimycin; Humans; Interleukin-2; Lymphocyte Activation; Middle Aged; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine | 1987 |
Modulation of surface CD11/CD18 glycoproteins (Mo1, LFA-1, p150,95) by human mononuclear phagocytes.
Topics: Animals; Antigens, Differentiation; Antigens, Surface; Blood Proteins; Calcimycin; Humans; Lymphocyte Function-Associated Antigen-1; Macrophage Activation; Macrophage-1 Antigen; Macrophages; Membrane Glycoproteins; Milk; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1988 |
Co-induction of lymphokine synthesis by the antineoplastic bryostatins.
Topics: Antineoplastic Agents; Bryostatins; Calcimycin; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-2; Kinetics; Lactones; Lymphocytes; Lymphokines; Macrolides; Mitogens; Tetradecanoylphorbol Acetate | 1987 |
Lipoxygenase inhibitors suppress IL-2 synthesis: relationship with rise of [Ca++]i and the events dependent on protein kinase C activation.
Topics: Animals; Butylated Hydroxyanisole; Calcimycin; Calcium; Cell Line; Enzyme Activation; Humans; Interleukin-2; Kinetics; Lipoxygenase Inhibitors; Masoprocol; Mice; Phenols; Protein Kinase C; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1987 |
Datura lectin is both an anti-mitogen and a co-mitogen acting synergistically with phorbol ester.
Topics: Calcimycin; Datura stramonium; Drug Synergism; Humans; Lectins; Leukocytes, Mononuclear; Lymphocyte Activation; Plant Lectins; Plants, Medicinal; Plants, Toxic; Tetradecanoylphorbol Acetate; Tuberculin | 1988 |
Impaired mitogen-induced interferon-gamma production in rheumatoid arthritis and related diseases.
Topics: Adolescent; Adult; Aged; Arthritis, Reactive; Arthritis, Rheumatoid; Autoimmune Diseases; Calcimycin; Drug Synergism; Humans; Interferon-gamma; Lectins; Lupus Erythematosus, Systemic; Lymphocyte Activation; Middle Aged; Osteoarthritis; Receptors, Immunologic; Receptors, Interleukin-2; Scleroderma, Systemic; Tetradecanoylphorbol Acetate | 1988 |
Rapid phosphorylation of a specific 33-kDa protein (p33) associated with growth stimulated by murine and rat IL3 in different IL3-dependent cell lines, and its constitutive expression in a malignant independent clone.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Cell Division; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Concanavalin A; Culture Media; Interleukin-3; Interleukin-4; Interleukins; Kinetics; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Protein Kinase C; Rats; Recombinant Proteins; Spleen; Tetradecanoylphorbol Acetate | 1988 |
[Lymphokine production using IL-2-dependent human T-lymphocytes].
Topics: Calcimycin; Cells, Cultured; Concanavalin A; Humans; Interleukin-2; Lymphocyte Activation; Lymphokines; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors | 1987 |
Enhancement of mezerein-promoted papilloma formation by treatment with 12-O-tetradecanoylphorbol-13-acetate or mezerein prior to initiation.
Topics: Animals; Calcimycin; Diterpenes; Drug Synergism; Female; Hyperplasia; Mice; Papilloma; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1988 |
The AKR thymoma BW5147 is able to produce lymphokines when stimulated with calcium ionophore and phorbol ester.
Topics: Animals; Calcimycin; Cell Fusion; Cell Line; Colony-Stimulating Factors; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Hybridomas; Interferon-gamma; Interleukin-2; Interleukin-3; Lymphokines; Mice; Mice, Inbred AKR; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1988 |
Synthesis and release of platelet-activating factor by stimulated human mononuclear phagocytes.
Topics: Calcimycin; Cell Adhesion; Cell Differentiation; Humans; Macrophage Activation; Monocytes; Opsonin Proteins; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Interleukin-2 secretion and transmembrane signalling in burned patients.
Topics: Adult; Aged; Burns; Calcimycin; Calcium; Cells, Cultured; Female; Humans; Interleukin-2; Male; Middle Aged; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Immunologic; Receptors, Interleukin-2; Staphylococcal Protein A; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1988 |
A sensitive enzyme-linked immunosorbence assay for the c-fos and v-fos oncoproteins.
Topics: Animals; Blood; Calcimycin; Cell Line; Cell Line, Transformed; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gene Products, gag; HeLa Cells; Humans; Kinetics; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Rats; Retroviridae Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymus Gland | 1988 |
Inability of murine peritoneal macrophages to convert linoleic acid into arachidonic acid. Evidence of chain elongation.
Topics: Acetyltransferases; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Carbon Radioisotopes; Fatty Acid Elongases; Fatty Acids; Female; Linoleic Acid; Linoleic Acids; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phospholipids; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Broad spectrum anti-platelet activity of ticlopidine and PCR 4099 involves the suppression of the effects of released ADP.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Calcimycin; Clopidogrel; Diglycerides; Female; Platelet Aggregation Inhibitors; Rats; Serotonin; Tetradecanoylphorbol Acetate; Thrombin; Ticlopidine; Type C Phospholipases | 1987 |
Mechanism of thrombin-induced rise in platelet fructose 2,6-bisphosphate content. Studies using phorbol myristate acetate, dioctanoylglycerol and ionophore A23187.
Topics: Blood Platelets; Calcimycin; Calcium; Diglycerides; Egtazic Acid; Fructosediphosphates; Glycolysis; Hexosediphosphates; Humans; Indomethacin; Tetradecanoylphorbol Acetate; Thrombin | 1987 |
Demonstration of calcium-dependent phospholipase A2 activity in membrane preparation of rabbit neutrophils. Absence of activation by fMet-Leu-Phe, phorbol 12-myristate 13-acetate and A-kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cell Membrane; Enzyme Activation; In Vitro Techniques; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases; Phospholipases A; Phospholipases A2; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Tetradecanoylphorbol Acetate | 1988 |
Cyclosporin A inhibits proteolytic cleavage and degradation of membrane-bound protein kinase C in hepatocytes after stimulation by phorbol ester.
Topics: Animals; Calcimycin; Cells, Cultured; Cyclosporins; Liver; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
[Possible role of protein kinase C in the blocking of intercellular contacts by calcium].
Topics: Animals; Calcimycin; Calcium; Cell Line, Transformed; Cricetinae; Fibroblasts; Fluorescent Dyes; Intercellular Junctions; Isoquinolines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
The effects of glucagon and TH-glucagon on steroid metabolism in isolated rat hepatocytes.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Animals; Calcimycin; Cells, Cultured; Glucagon; Liver; Male; Rats; Rats, Inbred Strains; Steroid Hydroxylases; Tetradecanoylphorbol Acetate | 1988 |
Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor.
Topics: Calcimycin; Cells, Cultured; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Glycoproteins; Humans; Immunoassay; Interleukin-1; Kinetics; Plasminogen Inactivators; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Tumor Necrosis Factor-alpha; Umbilical Veins | 1988 |
Analysis of signal transduction in B chronic lymphocytic leukemia cells.
Topics: Antibodies, Neoplasm; B-Lymphocytes; Calcimycin; Drug Synergism; Enzyme Activation; Humans; Interleukin-2; Interleukin-4; Interleukins; Leukemia, Lymphoid; Neoplasm Proteins; Protein Kinase C; Receptors, Immunologic; Receptors, Interleukin-2; RNA, Neoplasm; Tetradecanoylphorbol Acetate | 1988 |
Triiodothyronine inhibits phorbol ester-induced thyrotropin release from elutriated bovine thyrotrophs.
Topics: Animals; Calcimycin; Cattle; Cells, Cultured; Kinetics; Pituitary Gland, Anterior; Tetradecanoylphorbol Acetate; Thyrotropin; Triiodothyronine | 1988 |
Anti-Ig-mediated proliferation of human B cells in the absence of protein kinase C.
Topics: Adult; Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcimycin; Calcium; Humans; Immunoglobulin M; Lymphocyte Activation; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
IL-2 receptor inducibility is blocked in cortical-type thymocytes.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Cell Differentiation; Cells, Cultured; Gene Expression Regulation; Lymphocyte Activation; Mice; Receptors, Immunologic; Receptors, Interleukin-2; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymus Gland | 1988 |
Mechanism(s) by which the transient removal of dopamine regulation potentiates the prolactin-releasing action of thyrotropin-releasing hormone.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Cells, Cultured; Dopamine; Female; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide | 1988 |
Role of protein kinase C in the control of vascular prostacyclin: study of phorbol esters effect in bovine aortic endothelium and smooth muscle.
Topics: Animals; Aorta; Calcimycin; Calcium; Cattle; Cells, Cultured; Drug Synergism; Endothelium, Vascular; Epoprostenol; Muscle, Smooth, Vascular; Protein Kinase C; Serotonin; Tetradecanoylphorbol Acetate | 1988 |
Abnormal T cells from MRL/Mp-lpr/lpr mice do not respond to anti-T-cell-receptor antibody or tumor promoter and calcium ionophore A23187 despite the presence of the T-cell-receptor complex and protein kinase c.
Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Caenorhabditis elegans Proteins; Calcimycin; Carrier Proteins; Cytosol; Drug Synergism; Interleukin-2; Lymph Nodes; Lymphocyte Activation; Mice; Mice, Inbred Strains; Precipitin Tests; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Drug; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Initial and sustained calcium mobilizations in the parietal cell during stimulations with gastrin, inositol trisphosphate, phorbol ester and exogenous diacylglycerol.
Topics: Adenosine Triphosphate; Aequorin; Animals; Benzofurans; Calcimycin; Calcium; Calcium Radioisotopes; Cytoplasm; Diglycerides; Egtazic Acid; Electron Probe Microanalysis; Fluorescent Dyes; Fura-2; Gastrins; Glycerides; Guinea Pigs; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Parietal Cells, Gastric; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1988 |
Adherence of human basophils to cultured umbilical vein endothelial cells.
Topics: Basophils; Calcimycin; Cations, Divalent; Cell Adhesion; Cell Line; Complement C5; Complement C5a; Cycloheximide; Dactinomycin; Endothelium, Vascular; Glucocorticoids; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Temperature; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins | 1988 |
Phorbol ester and A23187 have additive but mechanistically separate effects on vasopressin action in rabbit collecting tubule.
Topics: Alkaloids; Animals; Arginine Vasopressin; Calcimycin; Calcium; Enzyme Activation; Female; Indomethacin; Kidney Tubules; Kidney Tubules, Collecting; Protein Kinase Inhibitors; Protein Kinases; Rabbits; Staurosporine; Temperature; Tetradecanoylphorbol Acetate | 1988 |
Role of calcium in prolactin-stimulated c-myc gene expression and mitogenesis in Nb2 lymphoma cells.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; DNA; Egtazic Acid; Gallic Acid; Gene Expression Regulation; Lymphoma; Male; Prolactin; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Proto-Oncogenes; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Phorbol esters potentiate rapid dopamine release from median eminence and striatal synaptosomes.
Topics: Animals; Calcimycin; Calcium; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Hyperprolactinemia; Indomethacin; Kinetics; Male; Median Eminence; Phorbol Esters; Potassium; Protein Kinase C; Rats; Rats, Inbred Strains; Sphingosine; Synaptosomes; Tetradecanoylphorbol Acetate; Tritium; Veratridine | 1988 |
Enhancement of c-fos expression is associated with activated macrophages.
Topics: Animals; BCG Vaccine; Calcimycin; Calcitriol; Cell Line; DNA; Gene Expression Regulation; Hybrid Cells; Kinetics; Lipopolysaccharides; Lymphokines; Macrophage Activation; Macrophages; Mice; N-Formylmethionine Leucyl-Phenylalanine; Proto-Oncogene Proteins; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors.
Topics: Calcimycin; Culture Media; Humans; In Vitro Techniques; Kinetics; Lipoproteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Early steps in interferon-gamma production: possible involvement of Ca2+-calmodulin-dependent enzymes.
Topics: Animals; Calcimycin; Calcium; Calmodulin; Cells, Cultured; Humans; Interferon-gamma; Leukocytes, Mononuclear; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
Phorbol ester-induced upregulation of angiotensin II receptors in neuronal cultures is potentiated by a calcium ionophore.
Topics: Angiotensin II; Animals; Arsenicals; Brain; Calcimycin; Calcium Radioisotopes; Cells, Cultured; Drug Synergism; Neurons; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetradecanoylphorbol Acetate | 1988 |
Calcium ionophore and phorbol myristate acetate synergistically inhibited proteoglycan biosynthesis in articular chondrocytes by prostaglandin independent mechanism.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acids; Calcimycin; Cartilage, Articular; Diglycerides; Dinoprostone; Drug Synergism; Indomethacin; Prostaglandins E; Proteoglycans; Pyrazoles; Rabbits; Tetradecanoylphorbol Acetate | 1988 |
Effect of chemotactic factors on hexose transport in polymorphonuclear leucocytes.
Topics: 3-O-Methylglucose; Arachidonic Acid; Arachidonic Acids; Biological Transport; Blood; Calcimycin; Chemotactic Factors; Deoxyglucose; Glucose; Hexoses; Humans; Kinetics; Methylglucosides; Monosaccharide Transport Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Thrombin; Zymosan | 1988 |
Complex regulation of the T cell receptor alpha gene: three different modes of triggering induction.
Topics: Animals; Calcimycin; Cell Line; Cyclosporins; Gene Expression Regulation; Mice; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Receptors, Antigen, T-Cell; RNA Processing, Post-Transcriptional; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
C-fos gene activation in murine thymocytes by a mechanism independent of protein kinase C or a Ca2+ signal.
Topics: Animals; Calcimycin; Calcium; Concanavalin A; Drug Interactions; Enzyme Activation; Gene Expression Regulation; Mice; Mitosis; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1988 |
Structural modifications induced by TPA (12-O-tetradecanoyl phorbol-13-acetate) in sea urchin eggs.
Topics: Ammonium Chloride; Animals; Calcimycin; Calcium; Cell Membrane; Cytoplasmic Granules; Endocytosis; Exocytosis; Fertilization; Microscopy, Electron; Organoids; Ovum; Sea Urchins; Tetradecanoylphorbol Acetate | 1988 |
C-myc expression in lymphocytes of MRL/MP-lpr mice activated by A23187 and TPA.
Topics: Animals; Calcimycin; Cells, Cultured; Concanavalin A; Drug Synergism; Gene Expression Regulation; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred Strains; Oncogenes; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Release of prostaglandin E2 and thromboxane B2 by mixed isolated human lung cells.
Topics: Bradykinin; Calcimycin; Cells, Cultured; Dinoprostone; Humans; Immunoenzyme Techniques; Lung; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandins E; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1988 |
A burst-promoting activity derived from the human bone marrow stromal cell line KM-102 is identical to the granulocyte-macrophage colony-stimulating factor.
Topics: Amino Acid Sequence; Bone Marrow; Bone Marrow Cells; Calcimycin; Cell Line; Colony-Stimulating Factors; Granulocytes; Hematopoietic Stem Cells; Humans; Macrophages; Tetradecanoylphorbol Acetate | 1988 |
Selective activation and proliferation of cord T cells with tumor promoter and calcium-ionophore.
Topics: Calcimycin; Humans; Lymphocyte Activation; T-Lymphocytes; Tetradecanoylphorbol Acetate; Umbilical Cord | 1988 |
Paradoxical effects of amiloride analogs on protein phosphorylation and serotonin release induced by agonists in human platelets.
Topics: Amiloride; Blood Platelets; Blood Proteins; Calcimycin; Humans; Phosphorylation; Serotonin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thrombin | 1988 |
Characterization of the inhibition of U46619-mediated human platelet activation by the trimetoquinol isomers. Evidence for endoperoxide/thromboxane A2 receptor blockade.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Blood Platelets; Calcimycin; Humans; In Vitro Techniques; Inositol Phosphates; Isomerism; Isoquinolines; Optical Rotation; Phosphorylation; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Serotonin; Tetradecanoylphorbol Acetate; Tretoquinol | 1988 |
Serum and growth factors rapidly elicit phosphorylation of the Ca2+/calmodulin-dependent protein kinase II in intact quiescent rat 3Y1 cells.
Topics: Animals; Blood; Calcimycin; Cell Line; Fibroblasts; Growth Substances; Molecular Weight; Phosphorylation; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1988 |
Inhibition by gossypol of tumor promoter-induced arachidonic acid metabolism in rat peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; Gossypol; Macrophages; Male; Peritoneal Cavity; Plant Extracts; Prostaglandins E; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thapsigargin | 1988 |
Characterization of an islet-activating protein-sensitive site in mouse sperm that is involved in the zona pellucida-induced acrosome reaction.
Topics: Acrosome; Aminoacridines; Animals; Calcimycin; Calcium; Chlortetracycline; Female; Fluorescent Dyes; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Mice; Microscopy, Electron; Ovum; Pertussis Toxin; Quinuclidinyl Benzilate; Sperm Capacitation; Spermatozoa; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella; Zona Pellucida | 1988 |
Influence of activating stimulus on functional phenotype: interleukin 2 mRNA accumulation differentially induced by ionophore and receptor ligands in subsets of murine T cells.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Cell Survival; Cells, Cultured; Genes; Interleukin-2; Ligands; Mice; Mice, Inbred C57BL; Nucleic Acid Hybridization; Receptors, Antigen, T-Cell; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Ethanol-induced phospholipase C activation is inhibited by phorbol esters in isolated hepatocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminoquinolines; Animals; Calcimycin; Diglycerides; Enzyme Activation; Ethanol; Fluorescent Dyes; Isoquinolines; Liver; Male; Phenylephrine; Piperazines; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1988 |
Gonadal steroid effects on LH response to arachidonic acid and protein kinase C.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cells, Cultured; Enzyme Activation; Estradiol; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Melitten; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Testosterone; Tetradecanoylphorbol Acetate | 1988 |
Insulin regulation of pyruvate kinase activity in cultured rat hepatocytes, in the presence of vasopressin, ionophore A23187 or 4 beta-phorbol 12 beta-myristate 13 alpha-acetate.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; In Vitro Techniques; Insulin; Liver; Male; Pyruvate Kinase; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1988 |
Epidermal-growth-factor-induced formation of inositol phosphates in human A431 cells. Differences from the effect of bradykinin.
Topics: Bradykinin; Calcimycin; Calcium; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Epidermal Growth Factor; Histamine; Humans; Inositol Phosphates; Kinetics; Pertussis Toxin; Sugar Phosphates; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1988 |
Hydrogen peroxide generation in whole rat pancreatic islets; synergistic regulation by cytoplasmic free calcium and protein kinase-C.
Topics: Animals; Calcimycin; Calcium; Drug Synergism; Hydrogen Peroxide; Islets of Langerhans; Male; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1988 |
Stimulation of release of prostaglandins and thromboxanes from isolated guinea pig lung cells by bradykinin, f-Met-Leu-Phe, phorbol myristate, ionophore A23187, and leukotrienes.
Topics: Animals; Bradykinin; Calcimycin; Dinoprostone; Guinea Pigs; In Vitro Techniques; Leukotrienes; Lung; N-Formylmethionine Leucyl-Phenylalanine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1988 |
Appearance of a proliferation-associated antigen, gp125, on rat and human lymphocytes by co-stimulation with phorbol ester and calcium ionophore.
Topics: Animals; Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Humans; Kinetics; Lymphocyte Activation; Male; Nucleotides, Cyclic; Rats; Rats, Inbred Strains; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Calcium is essential in the fusion of mouse alveolar macrophages induced by 1 alpha,25-dihydroxyvitamin D3.
Topics: Animals; Calcimycin; Calcitriol; Calcium; Cell Fusion; Cells, Cultured; Macrophage Activation; Macrophages; Male; Mice; Microscopy, Electron, Scanning; Pulmonary Alveoli; Tetradecanoylphorbol Acetate | 1988 |
Two different molecular pathways account for low IL-2 receptor and c-myc mRNA expression by lpr Lyt-2- L3T4- T cells.
Topics: Animals; Calcimycin; Concanavalin A; Cycloheximide; Female; Interphase; Kinetics; Lymphocyte Activation; Male; Mice; Mice, Inbred Strains; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Does protein kinase C activation mediate thrombin-induced arachidonate release in human platelets?
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Calcium; Enzyme Activation; Gallic Acid; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoquinolines; Piperazines; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane B2 | 1988 |
Analysis of the stimulative effect of thapsigargin, a non-TPA-type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Carcinogens; Cytoplasm; In Vitro Techniques; Isoquinolines; Lyngbya Toxins; Macrophages; Male; N-Formylmethionine Leucyl-Phenylalanine; Peritoneal Cavity; Piperazines; Plant Extracts; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thapsigargin | 1988 |
Expression of tartrate-resistant acid phosphatase in B-CLL treated with phorbol ester or phorbol ester plus calcium ionophore.
Topics: Acid Phosphatase; Aged; B-Lymphocytes; Calcimycin; Drug Synergism; Female; Humans; Isoenzymes; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Prolymphocytic; Male; Middle Aged; Tartrates; Tetradecanoylphorbol Acetate | 1988 |
Antagonism of acetylcholine-mediated relaxation of rabbit pulmonary arteries by phorbol myristate acetate.
Topics: Acetylcholine; Analysis of Variance; Animals; Biological Factors; Calcimycin; Catalase; Free Radicals; Male; Muscle Contraction; Muscle Relaxation; Nitric Oxide; Pulmonary Artery; Rabbits; Tetradecanoylphorbol Acetate; Vasodilation | 1988 |
Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activation.
Topics: Animals; Calcimycin; Concanavalin A; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Activation induces a rapid reorganization of spectrin in lymphocytes.
Topics: Animals; Calcimycin; Calcium; Cell Line; Cell Membrane; Cytoplasm; Immunoenzyme Techniques; Interleukin-2; Kinetics; Lymphocyte Activation; Mice; Receptors, Antigen, T-Cell; Spectrin; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
Tumor-promoting phorbol esters stimulate the proliferation of interleukin-3 dependent cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Cell Division; Cell Survival; Colony-Stimulating Factors; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Interleukin-3; Isoquinolines; Phorbol 12,13-Dibutyrate; Phorbol Esters; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
Establishment and characterization of factor-dependent macrophage cell lines.
Topics: Animals; Calcimycin; Cell Division; Cell Line; Colony-Stimulating Factors; Culture Media; Drug Synergism; Interleukin-3; Macrophages; Mice; Tetradecanoylphorbol Acetate | 1988 |
Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relation to AIDS.
Topics: Acquired Immunodeficiency Syndrome; Benzofurans; Calcimycin; Calcium; Cell Division; Cytoplasm; Drug Interactions; Fluorescent Dyes; Fura-2; Humans; Interleukin-2; Lymphocytes; Phytohemagglutinins; Plant Extracts; Receptors, Interleukin-2; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thapsigargin | 1988 |
Metallothionein RNA levels in HL-60 cells. Effect of cadmium, differentiation, and protein kinase C activation.
Topics: Amino Acid Sequence; Base Sequence; Cadmium; Calcimycin; Calcitriol; Cell Differentiation; Cell Line; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; Metallothionein; Molecular Sequence Data; Oligonucleotide Probes; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Platelet-derived growth factor does not induce c-fos in NIH 3T3 cells expressing the EJ-ras oncogene.
Topics: Animals; Calcimycin; Cell Line, Transformed; Genes, ras; Humans; Mitogens; Platelet-Derived Growth Factor; Proto-Oncogenes; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymidine; Type C Phospholipases | 1988 |
Role of protein kinase C in the vesicular release of acetylcholine and norepinephrine from enteric neurons of the guinea pig small intestine.
Topics: Acetylcholine; Animals; Calcimycin; Female; Guinea Pigs; In Vitro Techniques; Intestine, Small; Male; Neurons; Norepinephrine; Ouabain; Potassium; Protein Kinase C; Tetradecanoylphorbol Acetate | 1988 |
Comparison of signals delivered through CD3 and CD2 for T-cell activation: the role of calcium influx and interleukin 1.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Calcium; Egtazic Acid; Fluorescence; Humans; Interleukin-1; Interleukin-2; Interleukins; Lymphocyte Activation; Monocytes; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
The role of calcium in mediating phorbol ester- and insulin-stimulated adipocyte lipogenesis.
Topics: Adipose Tissue; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Cells, Cultured; Glucose; Imidazoles; Insulin; Kinetics; Lipids; Male; Polymyxin B; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Verapamil | 1988 |
In vivo effects of Sn-1,2-dioctanoylglycerol, TPA and A23187 on hamster cheek pouch epithelium.
Topics: Animals; Calcimycin; Cell Division; Cheek; Connective Tissue; Connective Tissue Cells; Cricetinae; Diglycerides; Epithelial Cells; Epithelium; Fluocinolone Acetonide; Glycerides; Hyperplasia; Male; Mesocricetus; Mitosis; Mouth Mucosa; Tetradecanoylphorbol Acetate | 1988 |
Regulation of eicosanoid biosynthesis in vitro and in vivo by the marine natural product manoalide: a potent inactivator of venom phospholipases.
Topics: 6-Ketoprostaglandin F1 alpha; Analgesics; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; In Vitro Techniques; Macrophages; Male; Mice; Phospholipases; Phospholipases A; Phospholipases A2; SRS-A; Terpenes; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Expression and regulation of an antigen specific for endothelium involved in human lymphocyte homing.
Topics: Antibodies, Monoclonal; Antigens, Surface; Biological Factors; Calcimycin; Cell Movement; Cytokines; Endothelium, Vascular; Humans; Immunoenzyme Techniques; Interferon-gamma; Lymphocytes; Lymphokines; Receptors, Immunologic; Receptors, Lymphocyte Homing; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1988 |
Lymphocyte activation mechanisms and in vitro actions of immunosuppressive drugs: a comparison.
Topics: Calcimycin; Cell Line; Cells, Cultured; Cyclosporins; Humans; Immunosuppressive Agents; Lymphocyte Activation; Lymphocytes; Mercaptopurine; Methylprednisolone; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate | 1987 |
Relative roles of calcium derived from intra- and extracellular sources in dynamic luteinizing hormone release from perifused pituitary cells.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Egtazic Acid; Female; Gallopamil; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Penfluridol; Perfusion; Pituitary Gland; Protein Kinase C; Radioimmunoassay; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Protein kinase C and calcium ion in mitogenic response of macrophage-depleted human peripheral lymphocytes.
Topics: Animals; Calcimycin; Calcium; Diglycerides; Enzyme Activation; Lymphocyte Activation; Lymphocytes; Macrophages; Mitosis; Phosphoproteins; Phosphorylation; Phytohemagglutinins; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1985 |
Stimulation of hexose transport by human polymorphonuclear leukocytes: a possible role for protein kinase C.
Topics: Biological Transport, Active; Calcimycin; Cytochalasin B; Deoxyglucose; Diglycerides; Diterpenes; Hexoses; Humans; Isomerism; Neutrophils; Protein Kinase C; Protein Kinases; Terpenes; Tetradecanoylphorbol Acetate; Trifluoperazine | 1985 |
Prolactin stimulation of ornithine decarboxylase activity in the mammary gland may involve an activation of protein kinase C.
Topics: Animals; Calcimycin; Enzyme Activation; Female; Mammary Glands, Animal; Mice; Ornithine Decarboxylase; Pregnancy; Prolactin; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Diacylglycerols and protein kinase C. Potential amplifying mechanism for Ca2+-mediated gonadotropin-releasing hormone-stimulated luteinizing hormone release.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Diglycerides; Female; Glycerides; Luteinizing Hormone; Pituitary Gland; Pituitary Hormone-Releasing Hormones; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1985 |
Induction of ornithine decarboxylase activity by 1-oleoyl-2-acetyl-glycerol in isolated mouse epidermal cells.
Topics: Animals; Calcimycin; Cell Survival; Diglycerides; Enzyme Induction; Epidermis; Female; Glycerides; Mice; Oleic Acid; Oleic Acids; Ornithine Decarboxylase; Pregnancy; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Characterization of protein kinase C and its role in catecholamine secretion from bovine adrenal-medullary cells.
Topics: Adrenal Medulla; Animals; Calcimycin; Calcium; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Diglycerides; Phosphatidylserines; Protein Kinase C; Protein Kinases; Proteins; Tetradecanoylphorbol Acetate | 1985 |
Stimulation and inhibition of growth by EGF in different A431 cell clones is accompanied by the rapid induction of c-fos and c-myc proto-oncogenes.
Topics: Calcimycin; Cell Division; Cell Line; Epidermal Growth Factor; Humans; Oncogenes; Protein Biosynthesis; Protein Kinase C; Protein Kinases; Proto-Oncogene Mas; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Calcium mobilization potentiates prolactin release induced by protein kinase C activators.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Diglycerides; Dopamine; Enzyme Activation; Female; Marine Toxins; Oxocins; Pituitary Gland, Anterior; Prolactin; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1985 |
The phorbol ester TPA enhances A23187--but not carbachol- and high K+-induced catecholamine secretion from cultured bovine adrenal chromaffin cells.
Topics: Animals; Calcimycin; Carbachol; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Phorbols; Potassium; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1985 |
Effects of trifluoperazine on platelet activation.
Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Epinephrine; Humans; Phospholipases A; Phospholipases A2; Platelet Aggregation; Protein Kinase C; Protein Kinase Inhibitors; Serotonin; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane B2; Trifluoperazine | 1985 |
Synergistic stimulation of luteinizing hormone (LH) release by protein kinase C activators and Ca2+-ionophore.
Topics: Animals; Calcimycin; Diglycerides; Drug Synergism; Enzyme Activation; Female; Luteinizing Hormone; Pituitary Gland, Anterior; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1985 |
Anti-My-26: a monoclonal antibody inhibiting human phagocyte chemiluminescence.
Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Calcimycin; Granulocytes; Humans; Luminescent Measurements; Lymphocytes; Mice; Monocytes; Opsonin Proteins; Oxygen Consumption; Phagocytes; Tetradecanoylphorbol Acetate; Zymosan | 1985 |
Phorbol ester, calcium ionophore, or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000-dalton mammalian stress proteins.
Topics: Animals; Blood; Calcimycin; Endopeptidases; Female; Fibroblasts; Heat-Shock Proteins; Leucine; Molecular Weight; Phorbols; Phosphoproteins; Phosphorylation; Pregnancy; Rats; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1985 |
Differential effects of phorbol ester on phenylephrine and vasopressin-induced Ca2+ mobilization in isolated hepatocytes.
Topics: Aminoquinolines; Animals; Calcimycin; Calcium; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Ethers; Ionomycin; Liver; Male; Phenylephrine; Phorbols; Phosphorylases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1985 |
Ca2+-dependent activation of oxoglutarate dehydrogenase by vasopressin in isolated hepatocytes.
Topics: Animals; Arginine Vasopressin; Calcimycin; Calcium; Enzyme Activation; Gluconeogenesis; In Vitro Techniques; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Liver; Male; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1985 |
Calcium ionophore enables soluble agonists to stimulate macrophage 5-lipoxygenase.
Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Enzyme Activation; In Vitro Techniques; Latex; Lipoxygenase; Macrophages; Mice; Mice, Inbred C57BL; Prostaglandin-Endoperoxide Synthases; SRS-A; Tetradecanoylphorbol Acetate; Zymosan | 1985 |
Regulation of arachidonic acid metabolism in macrophages by immune and nonimmune interferons.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Dinoprostone; Female; Interferon Type I; Interferon-gamma; Macrophages; Male; Mice; Mice, Inbred C3H; Prostaglandins E; Prostaglandins F; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1985 |
Arachidonic acid metabolism in cultured mouse keratinocytes.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Arachidonic Acids; Blood; Calcimycin; Cells, Cultured; Culture Media; Dinoprostone; Mice; Phospholipases; Phospholipids; Prostaglandins E; Skin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tritium | 1985 |
Inhibition of insulin receptor binding by A23187: synergy with phorbol esters.
Topics: Calcimycin; Cell Differentiation; Cell Line; Cytoplasm; Dihydroxycholecalciferols; Drug Synergism; Humans; Insulin; Monocytes; Phorbols; Protein Binding; Receptor, Insulin; Tetradecanoylphorbol Acetate | 1985 |
Synergistic stimulation of thromboxane biosynthesis by calcium ionophore and phorbol ester or thrombin in human platelets.
Topics: Blood Platelets; Calcimycin; Collagen; Drug Synergism; Humans; Phorbols; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane B2; Thromboxanes | 1985 |
Studies on the mechanism of phorbol ester-induced inhibition of intercellular junctional communication.
Topics: Animals; Calcimycin; Cell Communication; Cells, Cultured; Chlorpromazine; Cricetinae; Cricetulus; Diglycerides; Gallic Acid; Humans; Imidazoles; Phorbols; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1985 |
Phorbol esters and oleoyl acetoyl glycerol enhance release of arachidonic acid in platelets stimulated by Ca2+ ionophore A23187.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Diglycerides; Enzyme Activation; Fatty Acids, Unsaturated; Glycerides; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Phorbols; Phospholipases A; Phospholipases A2; Phospholipids; Phosphoproteins; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1985 |
Mitogen and co-mitogen stimulation of lymphocytes inhibited by three Ca++ antagonists.
Topics: Animals; Calcimycin; Calcium Channel Blockers; Cattle; Cell Division; Concanavalin A; Drug Synergism; Gallic Acid; Lectins; Lymphocyte Activation; Lymphocytes; Mitogens; Nicardipine; Nifedipine; Tetradecanoylphorbol Acetate; Time Factors; Verapamil; Wheat Germ Agglutinins | 1985 |
Tetanus toxin inhibits secretion of lysosomal contents from human macrophages.
Topics: beta-Galactosidase; Calcimycin; Cells, Cultured; Glucuronidase; Hexosaminidases; Hot Temperature; Humans; L-Lactate Dehydrogenase; Lysosomes; Macrophages; Muramidase; Peptide Fragments; Tetanus Toxin; Tetradecanoylphorbol Acetate | 1985 |
The mode of action of the calcium ionophore A23187 on T cell proliferation. I. The ionophore does not replace lymphokines but acts via induction of IL-2 production on IL-2 responsive cells.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Cell Division; Drug Synergism; Female; Interleukin-2; Lectins; Mice; Mice, Inbred BALB C; Peanut Agglutinin; Phorbols; Receptors, Immunologic; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1985 |
Stimulation of 1,2-diacylglycerol accumulation in hepatocytes by vasopressin, epinephrine, and angiotensin II.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcimycin; Calcium; Cell Membrane; Chromatography, High Pressure Liquid; Diglycerides; Egtazic Acid; Epinephrine; Fatty Acids; Glucagon; Glycerides; Kinetics; Liver; Male; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1985 |
Failure of 1-oleoyl-2-acetylglycerol to mimic the cell-differentiating action of 12-O-tetradecanoylphorbol 13-acetate in HL-60 cells.
Topics: Acid Phosphatase; Animals; Brain; Calcimycin; Cell Adhesion; Cell Differentiation; Cell Line; Diglycerides; Enzyme Activation; Glycerides; Humans; Leukemia, Myeloid; Mice; Molecular Weight; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1985 |
Oxidative degradation of leukotriene C4 by human monocytes and monocyte-derived macrophages.
Topics: Calcimycin; Cells, Cultured; Humans; Kinetics; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxidation-Reduction; SRS-A; Tetradecanoylphorbol Acetate | 1985 |
Modulation of Na/H exchange by a tumor promoting phorbol ester in different fibroblast cell lines.
Topics: Calcimycin; Cell Line; Fibroblasts; Humans; Hydrogen; Ion Exchange; Male; Phorbols; Sodium; Tetradecanoylphorbol Acetate | 1985 |
Comparison of patterns of prolactin release in GH4C1 cells and primary pituitary cultures.
Topics: Animals; Calcimycin; Cell Line; Cells, Cultured; Female; Kinetics; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1985 |
Synergistic action of A23187 and phorbol ester on human B cell activation.
Topics: B-Lymphocytes; Calcimycin; Drug Synergism; Humans; Immunoglobulins; Lymphocyte Activation; Palatine Tonsil; Phorbols; Spleen; Tetradecanoylphorbol Acetate | 1985 |
Structures of the major carbohydrates of natural human interleukin-2.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Calcimycin; Carbohydrates; Chromatography, Gel; Chromatography, High Pressure Liquid; DNA; Electrophoresis, Polyacrylamide Gel; Humans; Interleukin-2; Lymphocytes; Mass Spectrometry; Methylation; Tetradecanoylphorbol Acetate | 1985 |
A combination of calcium ionophore and 12-O-tetradecanoyl-phorbol-13-acetate (TPA) stimulates the growth of purified resting B cells.
Topics: B-Lymphocytes; Calcimycin; Cell Cycle; Dose-Response Relationship, Drug; Drug Synergism; Ethers; Humans; Ionomycin; Lymphocyte Activation; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Mechanism of inhibitory action of TMB-8 [8-(NN-diethylamino)octyl-3,4,5-trimethoxybenzoate] on aldosterone secretion in adrenal glomerulosa cells.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcimycin; Calcium; Cattle; Dose-Response Relationship, Drug; Gallic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Potassium; Protein Kinase C; Tetradecanoylphorbol Acetate | 1985 |
Interleukin 2 mRNA induction in human lymphocytes: analysis of the synergistic effect of a calcium ionophore A23187 and a phorbol ester.
Topics: Calcimycin; Calcium; Calmodulin; Cells, Cultured; Drug Synergism; Gallic Acid; Gene Expression Regulation; Interleukin-2; Palatine Tonsil; Phorbols; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1985 |
Rat neutrophil activation and effects of lipoxygenase and cyclooxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Antigen-Antibody Complex; Antioxidants; Calcimycin; Catechols; Cyclooxygenase Inhibitors; Cytochalasin B; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piroxicam; Pyrazoles; Pyrazolones; Rats; Superoxides; Tetradecanoylphorbol Acetate; Thiazines; Zymosan | 1984 |
Superoxide release by neutrophils: synergistic effects of a phorbol ester and a calcium ionophore.
Topics: Animals; Calcimycin; Calcium; Drug Synergism; Guinea Pigs; Kinetics; Magnesium; Neutrophils; Phorbols; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Mechanisms of regulating the respiratory burst in leukocytes.
Topics: Animals; Arachidonic Acids; Calcimycin; Calcium; Cytoplasmic Granules; Electric Conductivity; Granulomatous Disease, Chronic; Humans; Leukocytes; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nucleotides, Cyclic; Oxygen Consumption; Peroxidase; Protein Kinases; Tetradecanoylphorbol Acetate | 1984 |
Stimulation of hepatic glycogenolysis by 12-O-tetradecanoylphorbol-13-acetate (TPA) via a calcium requiring process.
Topics: Animals; Calcimycin; Calcium Chloride; Cyclic AMP; Cyclic GMP; Diltiazem; Glucose; Kinetics; Liver; Liver Glycogen; Male; Phorbols; Proteins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Trifluoperazine; Verapamil | 1984 |
Synergism between phorbol ester and A23187 in superoxide production by neutrophils.
Topics: Calcimycin; Drug Synergism; Humans; Kinetics; Neutrophils; Phorbols; Superoxides; Tetradecanoylphorbol Acetate | 1984 |
Synergistic stimulation of prolactin release by phorbol ester, A23187 and forskolin.
Topics: Animals; Calcimycin; Calcium; Cell Line; Colforsin; Cyclic AMP; Diterpenes; Drug Synergism; Phorbols; Pituitary Neoplasms; Prolactin; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Time Factors | 1984 |
A new physiological function for adenosine: regulation of superoxide anion production.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Anions; Calcimycin; Concanavalin A; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1983 |
Fc-receptor mediated protein phosphorylation in murine peritoneal macrophages.
Topics: Animals; Antigen-Antibody Complex; Bucladesine; Calcimycin; Cells, Cultured; Macrophages; Membrane Proteins; Mice; Mice, Inbred C57BL; Molecular Weight; Phosphoproteins; Phosphorylation; Receptors, Fc; Tetradecanoylphorbol Acetate | 1984 |
Agonist- and mitogen-induced desensitization of isoproterenol-stimulated cyclic AMP formation in mouse epidermis in vivo.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcimycin; Catecholamines; Cyclic AMP; Epidermis; Female; Isoproterenol; Mice; Mitogens; Phorbol Esters; Phorbols; Phosphoric Diester Hydrolases; Tetradecanoylphorbol Acetate | 1981 |
Beta-adrenoceptor antagonists and human platelets: relationship of effects to lipid solubility.
Topics: Adenosine Diphosphate; Adrenergic beta-Antagonists; Alprostadil; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcimycin; Collagen; Cyclic AMP; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Lipids; Platelet Aggregation; Propranolol; Prostaglandins E; Solubility; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1984 |
Fusion of intracellular membrane pools with cell surfaces of macrophages stimulated by phorbol esters and calcium ionophores.
Topics: Animals; Calcimycin; Cell Membrane; Endosomes; Intracellular Membranes; Macrophages; Phorbols; Rabbits; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin | 1984 |
The sequential release of granule constitutents from human neutrophils.
Topics: Calcimycin; Complement C5; Cytochalasin B; Cytoplasmic Granules; gamma-Globulins; Glucuronidase; Humans; Kinetics; Lactoferrin; Muramidase; N-Formylmethionine; Neutrophils; Oligopeptides; Peroxidase; Phenylalanine; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1980 |
Effect of 12-O-tetradecanoyl-phorbol-13-acetate on Ca2+ efflux and protein discharge in pancreatic acini.
Topics: Amylases; Animals; Calcimycin; Calcium; Carbachol; Ceruletide; Cyclic AMP; Cyclic GMP; Female; Guinea Pigs; Kinetics; Pancreas; Phorbols; Proteins; Tetradecanoylphorbol Acetate | 1981 |
Release of histamine from human leukocytes stimulated with the tumor-promoting phorbol diesters. II. Interaction with other stimuli.
Topics: Antibodies, Anti-Idiotypic; Calcimycin; Calcium; Carcinogens; Dose-Response Relationship, Drug; Drug Synergism; Histamine Release; Humans; Immunoglobulin E; Kinetics; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Histological, proliferative, and biochemical alterations in dorsal epidermis of the Syrian golden hamster induced by 12-O-tetradecanoylphorbol-13-acetate and the calcium ionophore A 23187.
Topics: Adaptation, Physiological; Administration, Topical; Animals; Anti-Bacterial Agents; Calcimycin; Cell Division; Cricetinae; Drug Resistance; Hyperplasia; Keratins; Male; Mesocricetus; Phorbols; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
Quantitative evaluation of dark keratinocytes induced by several promoting and hyperplasiogenic agents: their use as an early morphological indicator of tumor-promoting action.
Topics: Alkynes; Anthralin; Calcimycin; Carcinogens; Diterpenes; Epidermal Cells; Epidermis; Hyperplasia; Keratins; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate | 1982 |
The modulation of human basophil histamine release by products of the 5-lipoxygenase pathway.
Topics: Allergens; Antibodies, Anti-Idiotypic; Antigens, Plant; Arachidonic Acids; Basophils; Calcimycin; Dimaprit; Dinoprostone; Histamine Release; Humans; Immunoglobulin E; Leukotrienes; Lipoxygenase; Plant Proteins; Pollen; Prostaglandins E; Tetradecanoylphorbol Acetate; Thiourea | 1982 |
Effects of tumor promoters on the rate and commitment to terminal differentiation of subpopulations of murine keratinocytes.
Topics: Calcimycin; Carcinogens; Cell Differentiation; Cells, Cultured; Centrifugation, Density Gradient; Diterpenes; Keratins; Kinetics; Phorbol Esters; Skin; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
The role of calcium in macrophage chemotaxis to the phorbol ester tumor promoter TPA.
Topics: Animals; Calcimycin; Calcium; Chemotaxis; Egtazic Acid; Gallic Acid; In Vitro Techniques; Macrophages; Male; Mice; Mice, Inbred ICR; Phorbols; Ruthenium Red; Tetradecanoylphorbol Acetate | 1982 |
Calcium modulation of phorbol ester-induced alterations in murine macrophage morphology.
Topics: Animals; Calcimycin; Calcium; Cell Adhesion; Cell Count; Cytochalasin B; Dose-Response Relationship, Drug; Drug Interactions; Female; Gallic Acid; Macrophages; Mice; Mice, Inbred ICR; Phorbols; Ruthenium Red; Tetradecanoylphorbol Acetate | 1983 |
Role of phospholipase A2 activation in histamine release from human basophils.
Topics: Acetophenones; Basophils; Calcimycin; Histamine Release; Humans; Melitten; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate | 1983 |
Effect of prostaglandin D2 in modulating histamine release from human basophils.
Topics: Arachidonic Acids; Basophils; Calcimycin; Dimaprit; Dinoprostone; Histamine Release; Humans; Indomethacin; Leukotrienes; Prostaglandin D2; Prostaglandins D; Prostaglandins E; Receptors, Histamine H2; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiourea | 1984 |
Functional maturation of membrane potential changes and superoxide-producing capacity during differentiation of human granulocytes.
Topics: Adult; Calcimycin; Cell Differentiation; Cell Transformation, Neoplastic; Deoxyglucose; Dimethyl Sulfoxide; Gramicidin; Granulocytes; Humans; Leukemia, Myeloid; Membrane Potentials; Phagocytosis; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Non-promoting hyperplasiogenic agents do not mimic the effects of phorbol, 12-myristate, 13-acetate on terminal differentiation of normal and transformed human keratinocytes.
Topics: Alkynes; Calcimycin; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Clone Cells; Humans; Hyperplasia; Keratins; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1984 |
Synergistic effect of A23187 and a phorbol ester on amylase secretion from rabbit pancreatic acini.
Topics: Amylases; Animals; Calcimycin; Calcium; Carbachol; Dose-Response Relationship, Drug; Pancreas; Phorbols; Rabbits; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Synergistic action of protein kinase C and calcium for histamine release from rat peritoneal mast cells.
Topics: Animals; Ascitic Fluid; Calcimycin; Calcium; Concanavalin A; Cytosol; Diglycerides; Drug Synergism; Histamine Release; In Vitro Techniques; Mast Cells; Phosphoproteins; Protein Kinase C; Protein Kinases; Rats; Tetradecanoylphorbol Acetate | 1984 |
Auranofin, an oral chrysotherapeutic agent, inhibits histamine release from human basophils.
Topics: Asthma; Auranofin; Aurothioglucose; Basophils; Calcimycin; Gold; Gold Sodium Thiomalate; Histamine Release; Humans; Immunoglobulin E; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1984 |
Trifluoperazine and chlorpromazine block secretion from human platelets evoked at basal cytoplasmic free calcium by activators of C-kinase.
Topics: Blood Platelets; Calcimycin; Calcium; Chlorpromazine; Collagen; Enzyme Activation; Humans; Kinetics; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Thrombin; Trifluoperazine | 1983 |
Insulin secretion: combined effects of phorbol ester and A23187.
Topics: Animals; Calcimycin; Calmodulin; Drug Synergism; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Phorbols; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1983 |
Direct mitogenic effect of ionophore A23187 on isolated human T helper lymphocytes.
Topics: Calcimycin; Cell Separation; Humans; Lymphocyte Activation; Mitogens; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1984 |
Steroidogenic properties of phorbol ester and a Ca2+ ionophore in bovine adrenocortical cell suspensions.
Topics: Adrenal Cortex; Animals; Calcimycin; Cattle; Diglycerides; Hydrocortisone; In Vitro Techniques; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1984 |
Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium.
Topics: Animals; Antibodies, Monoclonal; Antigens; Calcimycin; CD3 Complex; Cell Line; Cell Membrane; Clone Cells; Humans; Interleukin-2; Leukemia; Lymphocyte Activation; Mice; Mutation; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1984 |
The temporal integration of the aldosterone secretory response to angiotensin occurs via two intracellular pathways.
Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Animals; Calcimycin; Calcium; Cattle; Cytosol; Dantrolene; Egtazic Acid; In Vitro Techniques; Inositol Phosphates; Kinetics; Phosphatidylinositols; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1984 |
1-(5-Isoquinolinesulfonyl)-2-methylpiperazine (H-7) is a selective inhibitor of protein kinase C in rabbit platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Calmodulin; Isoquinolines; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Rabbits; Tetradecanoylphorbol Acetate | 1984 |
Degranulating stimuli decrease the neagative surface charge and increase the adhesiveness of human neutrophils.
Topics: Calcimycin; Calcium; Cell Adhesion; Chemotactic Factors; Concanavalin A; Cytochalasin B; Humans; In Vitro Techniques; Lysosomes; Magnesium; Membrane Potentials; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate | 1980 |
Use of lipophilic probes of membrane potential to assess human neutrophil activation. Abnormality in chronic granulomatous disease.
Topics: Adolescent; Adult; Calcimycin; Carbocyanines; Chediak-Higashi Syndrome; Chemotactic Factors; Chemotaxis, Leukocyte; Child; Child, Preschool; Female; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Male; Membrane Potentials; Neutrophils; Onium Compounds; Superoxides; Tetradecanoylphorbol Acetate; Tetraphenylborate; Trityl Compounds; Valinomycin | 1980 |
Prostaglandin E-mediated mitogenic stimulation of mouse epidermis in vivo by divalent cation ionophore A 23187 and by tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Anti-Bacterial Agents; Calcimycin; Catecholamines; Cyclic AMP; Enzyme Induction; Epidermal Cells; Epidermis; Inflammation; Mast Cells; Mice; Mitosis; Phorbols; Prostaglandins E; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1981 |
Transmembrane potential changes associated with superoxide release from human granulocytes.
Topics: Calcimycin; Calcium; Concanavalin A; Granulocytes; Humans; Membrane Potentials; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Oxygen; Potassium; Sodium; Superoxides; Tetradecanoylphorbol Acetate | 1981 |
Respiratory burst enzyme in human neutrophils. Evidence for multiple mechanisms of activation.
Topics: Benzenesulfonates; Calcimycin; Concanavalin A; Diazonium Compounds; Enzyme Activation; Fluorides; Humans; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADP; Neutrophils; Oligopeptides; Oxygen Consumption; Sulfanilic Acids; Superoxides; Tetradecanoylphorbol Acetate | 1981 |
Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using an automatic enzyme immunoassay reader.
Topics: Animals; Calcimycin; Cells, Cultured; Computers; Female; Guinea Pigs; Hydrogen Peroxide; Immunoenzyme Techniques; Macrophages; Mice; Mice, Inbred C57BL; Oils; Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Thioglycolates | 1981 |
Neutrophil-degranulating action of 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid and 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. Comparison with other degranulating agents.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cattle; Chemotactic Factors; Cytochalasin B; Cytoplasmic Granules; Humans; In Vitro Techniques; Leukotriene B4; Lysophosphatidylcholines; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Rabbits; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1981 |
Correlation of human neutrophil secretion, chemoattractant receptor mobilization, and enhanced functional capacity.
Topics: 1-Butanol; Butanols; Calcimycin; Calcium; Chemotaxis, Leukocyte; Cycloheximide; Cytoplasmic Granules; Granulomatous Disease, Chronic; Humans; Hydrogen Peroxide; Lactoferrin; Methionine; Muramidase; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Pinocytosis; Puromycin; Receptors, Immunologic; Superoxides; Tetradecanoylphorbol Acetate | 1982 |
Evidence for 5, 12-dihydroxy-6,8,10,14-eicosatetraenoate as a mediator of human neutrophil aggregation.
Topics: Arachidonic Acids; Calcimycin; Cell Aggregation; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Humans; Kinetics; Leukotriene B4; Lysophosphatidylcholines; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1981 |
A rapid densitometric microassay for nitroblue tetrazolium reduction and application of the microassay to macrophages.
Topics: Animals; Calcimycin; Concanavalin A; Cytochrome c Group; Densitometry; Guinea Pigs; Macrophages; Microscopy; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Nitroblue Tetrazolium; Oligopeptides; Oxidation-Reduction; Photometry; Stimulation, Chemical; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tetrazolium Salts | 1981 |
Differences in the ability of human peripheral blood monocytes and in vitro monocyte-derived macrophages to produce superoxide anion: studies with cells from normals and patients with chronic granulomatous disease.
Topics: Adult; Calcimycin; Cells, Cultured; Female; Granulomatous Disease, Chronic; Humans; Infant; Macrophages; Male; Monocytes; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Opsonin Proteins; Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1982 |
Release of gelatinase from a novel secretory compartment of human neutrophils.
Topics: Calcimycin; Carrier Proteins; Cell Compartmentation; Cells, Cultured; Cytochalasin B; Cytoplasmic Granules; Exocytosis; Gelatinases; Humans; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Pepsin A; Superoxides; Tetradecanoylphorbol Acetate; Vitamin B 12 | 1982 |
Leukotriene B4 biosynthesis by alveolar macrophages.
Topics: Animals; Antioxidants; Arachidonic Acids; Calcimycin; Calcium; Catechols; Cells, Cultured; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Leukotriene B4; Macrophages; Masoprocol; Rabbits; Tetradecanoylphorbol Acetate; Zymosan | 1982 |
Effect of microtubule-disrupting agents on superoxide production in human polymorphonuclear leukocytes.
Topics: Alprostadil; Bucladesine; Calcimycin; Chemotactic Factors; Colchicine; Dipeptides; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Humans; Kinetics; Neutrophils; Oxygen; Prostaglandins E; Superoxides; Tetradecanoylphorbol Acetate; Thiocyanates | 1982 |
Comparison of the calcium ionophore and phorbol myristate acetate on the initiation of the respiratory burst in human neutrophils.
Topics: Anti-Bacterial Agents; Calcimycin; Dose-Response Relationship, Drug; Glucose; Humans; Luminescent Measurements; Neutrophils; Oxygen Consumption; Phorbols; Superoxides; Tetradecanoylphorbol Acetate | 1982 |
Unsaturated fatty acids as second messengers of superoxide generation by macrophages.
Topics: Animals; Calcimycin; Fatty Acids, Unsaturated; Guinea Pigs; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Oxygen; Phospholipases A; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1983 |
The effect of calcium on the secretion of factor VIII-related antigen by cultured human endothelial cells.
Topics: Antigens; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Endothelium; Factor VIII; Fluorescent Antibody Technique; Humans; Tetradecanoylphorbol Acetate; Thrombin; von Willebrand Factor | 1983 |
Calcium ionophore A-23187 and 12-O-tetradecanoyl-phorbol-13-acetate stimulation of prostaglandin synthesis in herpes simplex virus type 2-transformed rat cells.
Topics: Animals; Calcimycin; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Dinoprost; Dinoprostone; Embryo, Mammalian; Fibrosarcoma; Kinetics; Neoplasm Metastasis; Phorbols; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Simplexvirus; Tetradecanoylphorbol Acetate | 1984 |
Stimulus specificity of prostaglandin inhibition of rabbit polymorphonuclear leukocyte lysosomal enzyme release and superoxide anion production.
Topics: Acetylglucosaminidase; Animals; Calcimycin; Calcium; Chemotaxis, Leukocyte; Cyclic AMP; Cytochalasin B; Dose-Response Relationship, Drug; Epoprostenol; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prostaglandins E; Rabbits; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2; Zymosan | 1984 |
Phorbol esters inhibit alpha 1 adrenergic stimulation of glycogenolysis in isolated rat hepatocytes.
Topics: Angiotensin II; Animals; Calcimycin; Epinephrine; Female; In Vitro Techniques; Kinetics; Liver; Liver Glycogen; Phorbols; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Urea; Vasopressins | 1984 |
Phosphorylation of specific polypeptides induced by 12-O-tetradecanoylphorbol-13-acetate in chick embryo fibroblasts.
Topics: Animals; Calcimycin; Cells, Cultured; Chick Embryo; Cyclic AMP; Fibroblasts; Kinetics; Molecular Weight; Peptides; Phorbols; Phosphopeptides; Phosphorus Radioisotopes; Phosphorylation; Proteins; Tetradecanoylphorbol Acetate | 1984 |
Activation of the oxidative burst in human monocytes is associated with inhibition of methionine-dependent methylation of neutral lipids and phospholipids.
Topics: Calcimycin; Catalase; Cell Movement; Cytochrome c Group; Humans; Kinetics; Lipids; Methionine; Methylation; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Oxygen Consumption; Phospholipids; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tritium | 1984 |
Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters.
Topics: Animals; Blood Platelets; Caenorhabditis elegans Proteins; Calcimycin; Calcium; Carcinogens; Carrier Proteins; Enzyme Activation; Humans; Phorbols; Phospholipids; Phosphorylation; Protein Kinase C; Protein Kinases; Rats; Receptors, Cell Surface; Receptors, Drug; Serotonin; Tetradecanoylphorbol Acetate | 1984 |
Induction of plasminogen activator by 12-O-tetradecanoylphorbol-13-acetate and calcium ionophore. Suppression by inhibitors of fatty acid lipoxygenase.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Bacterial Agents; Arachidonic Acid; Arachidonic Acids; Calcimycin; Catechols; Cells, Cultured; Enzyme Induction; Fatty Acids; HeLa Cells; Humans; Hydroxyeicosatetraenoic Acids; Leukemia, Experimental; Lipoxygenase Inhibitors; Masoprocol; Phorbols; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate | 1983 |
Phorbol myristate acetate-induced macrophage aggregation.
Topics: Animals; Calcimycin; Calcium; Cell Aggregation; Guinea Pigs; Macrophages; Magnesium; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Synergistic functions of phorbol ester and calcium in serotonin release from human platelets.
Topics: Blood Platelets; Calcimycin; Calcium; Drug Synergism; Humans; In Vitro Techniques; Phorbol Esters; Phorbols; Phosphorylation; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1983 |
A novel type of cytoplasmic granule in bovine neutrophils.
Topics: Animals; Calcimycin; Cattle; Cytoplasmic Granules; Microscopy, Electron; Neutrophils; Oxygen; Phagocytosis; Tetradecanoylphorbol Acetate | 1983 |
Calcium-dependent activation of lymphocytes by ionophore, A23187, and a phorbol ester tumor promoter.
Topics: Animals; Anti-Bacterial Agents; Calcimycin; Calcium; Cattle; Concanavalin A; DNA; Egtazic Acid; Lymphocyte Activation; Lymphocytes; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.
Topics: Calcimycin; Cell Fractionation; Cell Membrane; Centrifugation, Density Gradient; Cytochrome b Group; Cytoplasmic Granules; Humans; Intracellular Membranes; Membrane Fusion; Neutrophils; Tetradecanoylphorbol Acetate | 1983 |
Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms.
Topics: Calcimycin; Chemotactic Factors; Complement C5; Complement C5a; Cytochalasin B; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Kinetics; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oligopeptides; Tetradecanoylphorbol Acetate | 1983 |
Mechanism of action of phorbol myristate acetate on human natural killer cell activity.
Topics: Calcimycin; Cell Adhesion; Cell Line; Cytochalasins; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Kinetics; Leukemia, Myeloid, Acute; Mycotoxins; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Aldosterone secretion: effect of phorbol ester and A23187.
Topics: Adrenal Medulla; Aldosterone; Angiotensin II; Animals; Calcimycin; Calcium; Phorbols; Swine; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
Ca2+-dependent stimulation of hexose transport by A23187, 12-O-tetradecanoylphorbol-13-acetate and epidermal growth factor in mouse fibroblasts.
Topics: Animals; Biological Transport, Active; Calcimycin; Calcium; Deoxy Sugars; Deoxyglucose; Egtazic Acid; Epidermal Growth Factor; Fibroblasts; Mice; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Regulation of arachidonic acid metabolism in Madin-Darby canine kidney cells. Comparison of A23187 and 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cycloheximide; Dinoprostone; Dogs; Kidney; Phorbols; Prostaglandins E; Tetradecanoylphorbol Acetate | 1984 |
Effects of the skin mitogens tumor-promotor 12-O-tetradecanoylphorbol 13-acetate and divalent-cation-ionophore A23187 on ion fluxes and membrane potential in a murine epidermal cell line (HEL30) and in 3T3 fibroblasts.
Topics: Animals; Arachidonic Acids; Biological Transport; Calcimycin; Cations, Divalent; Cell Division; Cell Line; Epidermis; Fibroblasts; Hyperplasia; Membrane Potentials; Mice; Mitogens; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Synergistic activation of rat hepatocyte glycogen phosphorylase by A23187 and phorbol ester.
Topics: Animals; Calcimycin; Drug Synergism; Enzyme Activation; Female; Kinetics; Liver; Phorbols; Phosphorylases; Rats; Tetradecanoylphorbol Acetate; Vasopressins | 1984 |
Monoclonal antibody to human granulocytes: cellular specificity and functional studies.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Digitonin; Female; Humans; Mice; Mice, Inbred BALB C; Muramidase; Neutrophils; Oxygen Consumption; Tetradecanoylphorbol Acetate | 1984 |
The NADPH oxidase of human polymorphonuclear leukocytes. Evidence for regulation by multiple signals.
Topics: Calcimycin; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Tetradecanoylphorbol Acetate | 1984 |
Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils.
Topics: Animals; Blood Proteins; Calcimycin; Carcinogens; Cytochalasin B; Kinetics; Lysosomes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol Esters; Phorbols; Phosphorylation; Protein Kinases; Rabbits; Tetradecanoylphorbol Acetate; Trifluoperazine | 1984 |
Isolation of a storage and secretory organelle containing Von Willebrand protein from cultured human endothelial cells.
Topics: Blood Coagulation Factors; Calcimycin; Cell Fractionation; Cells, Cultured; Centrifugation, Density Gradient; Endothelium; Humans; Organoids; Tetradecanoylphorbol Acetate; Umbilical Veins; von Willebrand Factor | 1984 |
Localization of histaminase to the specific granule of the human neutrophil.
Topics: Amine Oxidase (Copper-Containing); Calcimycin; Cell Fractionation; Centrifugation, Density Gradient; Concanavalin A; Cytochalasin B; Cytoplasmic Granules; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1984 |
TPA-induced contraction of isolated rabbit vascular smooth muscle.
Topics: Animals; Arteries; Calcimycin; Calcium; Colforsin; Diterpenes; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Kinase; Phorbols; Phosphorylation; Protein Kinases; Rabbits; Tetradecanoylphorbol Acetate | 1984 |
Exocytosis by neutrophils.
Topics: Animals; Calcimycin; Cell Compartmentation; Cytochalasin B; Exocytosis; Muramidase; Neutrophils; Oxygen Consumption; Peroxidases; Phagocytosis; Rabbits; Tetradecanoylphorbol Acetate | 1984 |
Pharmacological control of leukotriene and prostaglandin production from mouse peritoneal macrophages.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Calcimycin; Dinoprostone; Drug Interactions; In Vitro Techniques; Macrophages; Mice; Peritoneum; Prostaglandins; Prostaglandins E; SRS-A; Tetradecanoylphorbol Acetate | 1984 |
Diacylglycerols enhance human neutrophil degranulation responses: relevancy to a multiple mediator hypothesis of cell function.
Topics: Animals; Calcimycin; Cytoplasmic Granules; Diglycerides; Glycerides; Humans; Kinetics; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
Effect of calmidazolium and phorbol ester on catecholamine secretion from adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcimycin; Carbachol; Catecholamines; Cattle; Chromaffin Granules; Enzyme Inhibitors; Imidazoles; Kinetics; Phorbols; Potassium; Tetradecanoylphorbol Acetate | 1984 |
A comparison of the effects of soluble stimuli on free cytoplasmic and membrane bound calcium in human neutrophils.
Topics: Adult; Aminoquinolines; Calcimycin; Calcium; Cytochalasin B; Cytoplasm; Fluorescent Dyes; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1984 |
A phorbol ester and A23187 act synergistically to release acetylcholine from the guinea pig ileum.
Topics: Acetylcholine; Animals; Calcimycin; Calcium; Choline; Drug Synergism; Electric Stimulation; Female; Guinea Pigs; Ileum; Kinetics; Male; Phorbols; Tetradecanoylphorbol Acetate; Tritium | 1984 |
Thrombin-induced release of von Willebrand factor from endothelial cells is mediated by phospholipid methylation. Prostacyclin synthesis is independent of phospholipid methylation.
Topics: Blood Coagulation Factors; Calcimycin; Calcium; Cells, Cultured; Edetic Acid; Endothelium; Epoprostenol; Female; Humans; Isomerism; Kinetics; Methylation; Phospholipids; Pregnancy; Tetradecanoylphorbol Acetate; Thrombin; Tubercidin; Umbilical Veins; von Willebrand Factor | 1984 |
Phorbol esters as probes of the regulation of thyrotropin secretion.
Topics: Animals; Calcimycin; Cycloheximide; Dose-Response Relationship, Drug; Male; Phorbol Esters; Phorbols; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thyrotropin; Thyrotropin-Releasing Hormone; Triiodothyronine | 1984 |
Degranulating stimuli increase the availability of receptors on human neutrophils for the chemoattractant f-met-leu-phe.
Topics: Binding Sites; Binding, Competitive; Calcimycin; Chemotaxis, Leukocyte; Cytochalasin B; Cytoplasmic Granules; Endotoxins; Escherichia coli; Glucuronidase; Humans; L-Lactate Dehydrogenase; Muramidase; Neutrophils; Oligopeptides; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone | 1980 |
Secretagogue modulation of the response of human neutrophils to chemoattractants: studies with a membrane potential sensitive cyanine dye.
Topics: Calcimycin; Carbocyanines; Chemotactic Factors; Chemotaxis, Leukocyte; Cytochalasin B; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Membrane Potentials; Muramidase; Neutrophils; Peptides; Quinolines; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1980 |
Neutrophil aggregation: evidence for a different mechanism of action by phorbol myristate acetate.
Topics: Arachidonic Acids; Calcimycin; Calcium; Cell Aggregation; Cytochalasin B; Dose-Response Relationship, Drug; Glucose; Humans; In Vitro Techniques; Magnesium; Neutrophils; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in culture.
Topics: Animals; Calcimycin; Cells, Cultured; Colorimetry; Concanavalin A; Guinea Pigs; Hydrogen Peroxide; Lectins; Macrophages; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Phenolsulfonphthalein; Tetradecanoylphorbol Acetate; Zymosan | 1980 |
Abnormal responses of granulocytes in chronic granulomatous disease.
Topics: Calcimycin; Chemotactic Factors; Concanavalin A; Granulocytes; Granulomatous Disease, Chronic; Humans; In Vitro Techniques; Membrane Potentials; Tetradecanoylphorbol Acetate | 1981 |
Chemiluminescence of human neutrophils induced by soluble stimuli: effect of divalent cations.
Topics: Anti-Bacterial Agents; Calcimycin; Calcium; Cations, Divalent; Concanavalin A; Dose-Response Relationship, Drug; Edetic Acid; Egtazic Acid; Humans; Luminescent Measurements; Magnesium; Neutrophils; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Interaction of phorbol esters with lipid bilayers : thermotropic changes in fluorescence polarization, phase transition and calcium ionophoresis.
Topics: Calcimycin; Calcium; Carcinogens; Diffusion; Dimyristoylphosphatidylcholine; Lipid Bilayers; Phorbol Esters; Phorbols; Phosphatidylcholines; Pulmonary Surfactants; Spectrometry, Fluorescence; Structure-Activity Relationship; Temperature; Tetradecanoylphorbol Acetate | 1981 |
T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes.
Topics: Animals; Calcimycin; Calcium; Cell Membrane; Membrane Potentials; Mice; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland; Wine | 1982 |
On the relationship between epidermal hyperproliferation and skin tumor promotion.
Topics: Calcimycin; Cell Division; Cocarcinogenesis; Dinoprost; Dinoprostone; Epidermal Cells; Hyperplasia; Indomethacin; Prostaglandins E; Prostaglandins F; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1982 |
Ionophoretic effect of tumor promoter phorbol diester: a clue to its insulinotropic action?
Topics: Animals; Biological Transport; Calcimycin; Calcium; Glucose; Insulin; Islets of Langerhans; Liposomes; Membrane Fluidity; Phorbols; Rats; Tetradecanoylphorbol Acetate | 1982 |
Synthesis of thromboplastin by U-937 cells.
Topics: Antigen-Antibody Complex; Calcimycin; Cell Division; Cell Line; Dose-Response Relationship, Drug; Endotoxins; Humans; Lymphocyte Cooperation; Phytohemagglutinins; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thromboplastin; Trypsin | 1982 |
Calcium-dependent release of arachidonic acid from a murine epidermal cell line induced by the tumor promoter TPA or ionophore A 23187: dissection of ionophoretic and phospholipase A2-stimulating activity.
Topics: Animals; Anti-Bacterial Agents; Arachidonic Acid; Arachidonic Acids; Biological Transport; Calcimycin; Calcium; Cell Line; Enzyme Activation; Ionophores; Mice; Phorbols; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate | 1982 |
Endogenous phospholipid metabolism in stimulated neutrophils differential activation by FMLP and PMA.
Topics: Calcimycin; Chemotactic Factors; Humans; Kinetics; Methionine; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Phorbols; Phospholipids; Tetradecanoylphorbol Acetate | 1982 |
Is the E receptor on human T lymphocytes a "negative signal receptor"?
Topics: Calcimycin; Cells, Cultured; Concanavalin A; Erythrocytes; Humans; Interleukin-2; Lymphocyte Activation; Mitogens; Receptors, Immunologic; Receptors, Mitogen; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1982 |
Essential and nonessential cooperative signals in lymphocyte triggering in solid cultures.
Topics: Calcimycin; Cell Adhesion; Culture Media; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Leukocytes; Lymphocyte Activation; Lymphocyte Cooperation; Mercaptoethanol; Phytohemagglutinins; Rosette Formation; Tetradecanoylphorbol Acetate | 1980 |
Influence of calcium on arachidonic acid mobilization by murine resident peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Cell Membrane; Cytosol; Enzyme Activation; Enzyme Inhibitors; Ionophores; Macrophages, Peritoneal; Male; Mice; Phospholipases A; Phospholipases A2; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
Regulated and unregulated pathways for MUC2 mucin secretion in human colonic LS180 adenocarcinoma cells are distinct.
Topics: Adenocarcinoma; Biomarkers, Tumor; Calcimycin; Carbachol; Cell Size; Colchicine; Colonic Neoplasms; Cytochalasin D; Cytoplasmic Granules; Golgi Apparatus; Humans; Microscopy, Electron; Monensin; Mucin-2; Mucins; Neoplasm Proteins; Nocodazole; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Induction of apoptosis in cultured retinoblastoma cells by the protein phosphatase inhibitor, okadaic acid.
Topics: Apoptosis; Calcimycin; Cell Cycle; Cell Survival; Child, Preschool; Cholera Toxin; Colforsin; DNA, Neoplasm; Enzyme Inhibitors; Ethers, Cyclic; Etoposide; Flow Cytometry; HL-60 Cells; Humans; Male; Mitosis; Nocodazole; Okadaic Acid; Paclitaxel; Phosphoprotein Phosphatases; Retinoblastoma; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1995 |
Expression of interleukin-11 and its encoding mRNA by glioblastoma cells.
Topics: Astrocytes; Blotting, Northern; Calcimycin; Cell Line; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Genetic Code; Glioblastoma; Humans; Interleukin-1; Interleukin-11; Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Beta 1 integrin-mediated T cell adhesion is regulated by calcium ionophores and endoplasmic reticulum Ca(2+)-ATPase inhibitors.
Topics: Antibodies, Monoclonal; Antioxidants; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Adhesion; Cells, Cultured; Collagen; Endoplasmic Reticulum; Fibronectins; Humans; Hydroquinones; Indoles; Integrin beta1; Integrins; Ionomycin; Laminin; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1993 |
Nimesulide, a sulfonanilide nonsteroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells.
Topics: Adolescent; Adult; Alprostadil; Amino Acid Sequence; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basophils; Bryostatins; Calcimycin; Colforsin; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Lactones; Leukotriene C4; Lung; Macrolides; Mast Cells; Middle Aged; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Prostaglandin D2; Skin; Sulfonamides; Tetradecanoylphorbol Acetate | 1993 |
Signal transduction pathways mediating astrocyte IL-6 induction by IL-1 beta and tumor necrosis factor-alpha.
Topics: Animals; Animals, Newborn; Astrocytes; Calcimycin; Calcium; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; In Vitro Techniques; Interleukin-1; Interleukin-6; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rats; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
Pharmacological investigations with different protein kinase C inhibitors on IgE-dependent and IgE-independent activation of human basophils.
Topics: Alkaloids; Basophils; Calcimycin; Exocytosis; Histamine; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Receptors, IgE; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Stimulation of RNA synthesis in rat parotid lobules by phorbol myristate acetate.
Topics: Alkaloids; Animals; Calcimycin; Gene Expression Regulation; Parotid Gland; Protein Kinase C; Rats; RNA; Salivary Proteins and Peptides; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Up-Regulation | 1993 |
Regulation of glycoprotein hormone free alpha-subunit secretion and intracellular alpha-subunit content in primary pituitary cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Cells, Cultured; Female; Gene Expression Regulation; Glycoprotein Hormones, alpha Subunit; Gonadotropin-Releasing Hormone; Kinetics; Luteinizing Hormone; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Time Factors; Verapamil | 1994 |
Epidermal growth factor induces acrosomal exocytosis in bovine sperm.
Topics: Acrosome; Animals; Bucladesine; Calcimycin; Calcium; Cattle; Epidermal Growth Factor; ErbB Receptors; Exocytosis; Male; Phosphotyrosine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Inhibition of IgE- and non-IgE-mediated histamine release from human basophil leukocytes in vitro by a histamine H1-antagonist, desethoxycarbonyl-loratadine.
Topics: Basophils; Calcimycin; Concanavalin A; Histamine H1 Antagonists; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Loratadine; N-Formylmethionine Leucyl-Phenylalanine; Rhinitis, Allergic, Seasonal; Tetradecanoylphorbol Acetate | 1994 |
Calcium and protein kinase C regulation of the glucocorticoid receptor in mouse corticotrope tumor cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Cycloheximide; Dexamethasone; Enzyme Activation; Kinetics; Mice; Pituitary Neoplasms; Protein Kinase C; Receptors, Glucocorticoid; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Two proteolytic pathways for down-regulation of the barrier molecule CD43 of human neutrophils.
Topics: Antigens, CD; Calcimycin; Calcium; CD18 Antigens; Cell Adhesion Molecules; Down-Regulation; Endopeptidases; Humans; Interleukin-8; L-Selectin; Leukosialin; Macrophage-1 Antigen; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Protease Inhibitors; Sialoglycoproteins; Tetradecanoylphorbol Acetate | 1994 |
B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10.
Topics: Animals; Antibodies, Monoclonal; B7-1 Antigen; Base Sequence; Calcimycin; CD28 Antigens; Cell Line; DNA Primers; Gene Expression; Humans; In Vitro Techniques; Interleukin-10; Interleukin-5; Interphase; Lymphocyte Activation; Mice; Molecular Sequence Data; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1994 |
Studies on the induction of cyclooxygenase isozymes by various prostaglandins in mouse osteoblastic cell line with reference to signal transduction pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alprostadil; Animals; Base Sequence; Calcimycin; Cell Line; Cycloheximide; Dexamethasone; Enzyme Induction; Iloprost; Isoenzymes; Isoquinolines; Mice; Molecular Sequence Data; Piperazines; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate | 1994 |
Regulation of human chorionic gonadotropin secretion and messenger ribonucleic acid levels by follistatin in the NUCC-3 choriocarcinoma cell line.
Topics: Calcimycin; Choriocarcinoma; Chorionic Gonadotropin; Chorionic Gonadotropin, beta Subunit, Human; Colforsin; Follistatin; Gene Expression Regulation; Glycoprotein Hormones, alpha Subunit; Glycoproteins; Gonadotropin-Releasing Hormone; Half-Life; Humans; Kinetics; Peptide Fragments; Placenta; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Pituitary adenylate cyclase-activating polypeptide effects in pituitary cells: modulation by gonadotropin-releasing hormone in alpha T3-1 cells.
Topics: 1-Methyl-3-isobutylxanthine; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activation; Gonadotropin-Releasing Hormone; Neuropeptides; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Regulation of endothelin-1- and lysophosphatidic acid-stimulated tyrosine phosphorylation of focal adhesion kinase (pp125fak) in Rat-1 fibroblasts.
Topics: Amino Acid Sequence; Animals; Calcimycin; Calcium; Cell Adhesion Molecules; Cell Line; Egtazic Acid; Endothelins; Fibroblasts; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Homeostasis; Immunosorbent Techniques; Kinetics; Lysophospholipids; Molecular Sequence Data; Pertussis Toxin; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Tetradecanoylphorbol Acetate; Tyrosine; Virulence Factors, Bordetella | 1994 |
Lipopolysaccharide primes human basophils for enhanced mediator release: requirement for plasma co-factor and CD14.
Topics: Acute-Phase Proteins; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arachidonic Acid; Basophils; Calcimycin; Carrier Proteins; Histamine Release; Humans; Immunoglobulin E; Kinetics; Lipopolysaccharide Receptors; Lipopolysaccharides; Membrane Glycoproteins; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate | 1994 |
Investigations with the selective PKC inhibitor chelerythrine on human basophils.
Topics: Alkaloids; Basophils; Benzophenanthridines; Calcimycin; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Phenanthridines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Annexin 3 is associated with cytoplasmic granules in neutrophils and monocytes and translocates to the plasma membrane in activated cells.
Topics: Annexin A3; Calcimycin; Cell Differentiation; Cell Fractionation; Cell Membrane; Cytoplasmic Granules; Cytosol; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Humans; Immunoblotting; Intracellular Membranes; Microscopy, Fluorescence; Molecular Weight; Monocytes; Neutrophils; Phagosomes; Staining and Labeling; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Cytotoxic CD8+ T lymphocytes reactive with human immunodeficiency virus-1 produce granulocyte/macrophage colony-stimulating factor and variable amounts of interleukins 2, 3, and 4 following stimulation with the cognate epitope.
Topics: Calcimycin; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; Clone Cells; Epitopes; Granulocyte-Macrophage Colony-Stimulating Factor; HIV-1; Humans; Interleukin-2; Interleukin-3; Interleukin-4; Kinetics; Lymphocyte Activation; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
PMA and calcium ionophore induce myosin and F-actin rearrangement during histamine secretion from RBL-2H3 cells.
Topics: Actins; Animals; Calcimycin; Calcium; Cell Membrane; Cell Size; Histamine Release; Leukemia, Basophilic, Acute; Maleimides; Mast Cells; Microscopy, Fluorescence; Myosins; Protein Kinase C; Rats; Serotonin; Tetradecanoylphorbol Acetate; Tritium; Tubulin; Tumor Cells, Cultured; Vimentin | 1994 |
Activated mast cells produce interleukin 13.
Topics: Animals; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; Base Sequence; Basophils; Bone Marrow Cells; Calcimycin; CD40 Antigens; Cell Line; Gene Expression Regulation; Gene Rearrangement, B-Lymphocyte; Humans; Immunoglobulin Class Switching; Immunoglobulin E; Interleukin-13; Interleukin-4; Mast Cells; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Polymerase Chain Reaction; Receptors, IgE; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
Induction of bovine bronchial epithelial cell filopodia by tetradecanoyl phorbol acetate, calcium ionophore, and lysophosphatidic acid.
Topics: Actins; Animals; Bronchi; Calcimycin; Cattle; Cells, Cultured; Epithelial Cells; Epithelium; Fibronectins; Glycoproteins; Hormones; Lysophospholipids; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate; Trypsin; Vitronectin | 1995 |
Interleukin-6 production by U373 MG, a human astrocytoma cell line: different pathways involved in substance P and lipopolysaccharide activation.
Topics: Alkaloids; Astrocytoma; Bucladesine; Calcimycin; Cholera Toxin; Humans; Indomethacin; Interleukin-6; Lipopolysaccharides; Receptors, Neurokinin-1; Staurosporine; Substance P; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
The molecular mechanism of FasL-mediated cytotoxicity by CD4+ Th1 clones.
Topics: Animals; Antigens, Surface; Base Sequence; Calcimycin; CD4 Antigens; Clone Cells; Cycloheximide; Cytotoxicity, Immunologic; Egtazic Acid; Fas Ligand Protein; fas Receptor; Immunoglobulins; Lymphocyte Activation; Magnesium Chloride; Membrane Glycoproteins; Mice; Molecular Sequence Data; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Th1 Cells | 1995 |
Platelet phospholipase D is activated by protein kinase C via an integrin alpha IIb beta 3-independent mechanism.
Topics: Amino Acid Sequence; Blood Platelets; Calcimycin; Collagen; Enzyme Activation; Humans; Indoles; Integrins; Kinetics; Oligopeptides; Phospholipase D; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Receptors, Cytoadhesin; Tetradecanoylphorbol Acetate; Thrombin | 1995 |
Aggregation of IgE receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase HePTP.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; Calcimycin; Calcium; Cell Line; Cloning, Molecular; Cytosol; DNA Primers; Gene Expression; Immunoblotting; Intracellular Signaling Peptides and Proteins; Leukemia, Basophilic, Acute; Mice; Molecular Sequence Data; Organ Specificity; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein Tyrosine Phosphatases, Non-Receptor; Rats; Receptors, IgE; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1995 |
Biphasic effect of staurosporine on thymocyte apoptosis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Apoptosis; Bucladesine; Calcimycin; Carbazoles; Carcinogens; Cells, Cultured; DNA; DNA Damage; Dose-Response Relationship, Drug; Indole Alkaloids; Isoquinolines; Male; Mice; Mice, Inbred BALB C; Piperazines; Protein Kinase Inhibitors; Radiation-Sensitizing Agents; Staurosporine; Tetradecanoylphorbol Acetate; Thymus Gland; Time Factors | 1995 |
Up-regulation of high-affinity dehydroepiandrosterone binding activity by dehydroepiandrosterone in activated human T lymphocytes.
Topics: Binding Sites; Calcimycin; Cell Line; Dehydroepiandrosterone; Humans; Ionophores; Kinetics; Lymphocyte Activation; Receptors, Steroid; Steroids; Structure-Activity Relationship; T-Lymphocytes; Tetradecanoylphorbol Acetate; Up-Regulation | 1995 |
Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions.
Topics: Arachidonate 15-Lipoxygenase; Aspirin; Calcimycin; Carboxypeptidases; Cell Communication; Cells, Cultured; Chromatography, High Pressure Liquid; Drug Interactions; Eicosanoids; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Gas Chromatography-Mass Spectrometry; Humans; Interleukin-1; Neutrophils; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Thrombin | 1995 |
Role of cytosolic phospholipase A2 in arachidonic acid release of rat-liver macrophages: regulation by Ca2+ and phosphorylation.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Enzyme Activation; Kinetics; Lipopolysaccharides; Liver; Macrophages; Male; Phospholipases A; Phospholipases A2; Phosphorylation; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Zymosan | 1995 |
Focal adhesion formation is associated with secretion of allergic mediators.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Cell Adhesion; Cell Line; Cell Membrane; Cell Membrane Permeability; Dinitrophenols; Immunoblotting; Mast Cells; Rats; Serum Albumin, Bovine; Talin; Tetradecanoylphorbol Acetate; Vinculin | 1995 |
A zinc metalloproteinase is responsible for the release of CD30 on human tumor cell lines.
Topics: Antibodies, Monoclonal; Calcimycin; Down-Regulation; Glycosylation; Hodgkin Disease; Humans; Iodoacetamide; Ionophores; Ki-1 Antigen; Kinetics; Lymphoma, Non-Hodgkin; Metalloendopeptidases; Solubility; Sulfhydryl Reagents; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
IL-4 expression in human T cells is selectively inhibited by IL-1 alpha and IL-1 beta.
Topics: Base Sequence; Calcimycin; Cell Division; Cells, Cultured; DNA Primers; Humans; Interferon-gamma; Interleukin-1; Interleukin-2; Interleukin-4; Interleukin-6; Lymphocyte Activation; Molecular Sequence Data; Phytohemagglutinins; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
Extracellular Nef protein regulates productive HIV-1 infection from latency.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Base Sequence; Calcimycin; CD4 Antigens; CD4-Positive T-Lymphocytes; Cell Line; DNA Primers; Gene Products, nef; HIV-1; Humans; Models, Biological; Molecular Sequence Data; nef Gene Products, Human Immunodeficiency Virus; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Virus Activation; Virus Latency | 1995 |
A corticosteroid-induced gene expressing an "IsK-like" K+ channel activity in Xenopus oocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aldosterone; Amino Acid Sequence; Animals; Calcimycin; Colon; Dexamethasone; Female; Gene Expression; Gene Library; Intracellular Signaling Peptides and Proteins; Male; Membrane Potentials; Molecular Sequence Data; Oocytes; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Sorting Signals; Rats; Rats, Wistar; RNA, Complementary; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Xenopus laevis | 1995 |
Inhibition of inflammatory responses by epitaondiol and other marine natural products.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Calcimycin; Cytochrome c Group; Ear, External; Edema; Humans; Inflammation; Leukotriene B4; Mice; Neutrophils; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Sesquiterpenes; Steroids; Stimulation, Chemical; Superoxides; Terpenes; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1995 |
Novel function of prostaglandins as inducers of gene expression of HGF and putative mediators of tissue regeneration.
Topics: Alprostadil; Animals; Blotting, Western; Bucladesine; Calcimycin; Cells, Cultured; CHO Cells; Cricetinae; Culture Media, Conditioned; Dinoprostone; Electrophoresis, Polyacrylamide Gel; Epoprostenol; Fibroblasts; Gene Expression; Hepatocyte Growth Factor; Humans; Interleukin-1; Prostaglandin D2; Prostaglandins; Recombinant Proteins; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor beta | 1995 |
Ca2+ and cAMP activate different K+ conductances in the human intestinal goblet cell line HT29-Cl.16E.
Topics: Amphotericin B; Barium; Bumetanide; Calcimycin; Calcium; Carbachol; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Digitonin; Diphenylamine; Electric Conductivity; Epithelial Cells; Epithelium; Fura-2; Humans; Intestinal Mucosa; Membrane Potentials; Models, Biological; Ouabain; Potassium; Potassium Channels; Quinidine; Tetradecanoylphorbol Acetate; Thionucleotides; Vasoactive Intestinal Peptide | 1995 |
Cold acclimation induces zonal heterogeneity in gluconeogenic responses to glucagon in rat liver lobule.
Topics: Acclimatization; Animals; Bucladesine; Calcimycin; Cells, Cultured; Cold Temperature; Fructose-Bisphosphatase; Glucagon; Gluconeogenesis; Glutamate-Ammonia Ligase; Kinetics; Liver; Male; Norepinephrine; Phosphoenolpyruvate Carboxykinase (GTP); Phosphofructokinase-1; Pyruvate Kinase; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Calcium ionophores decrease pericellular gelatinolytic activity via inhibition of 92-kDa gelatinase expression and decrease of 72-kDa gelatinase activation.
Topics: Calcimycin; Calcium; Concanavalin A; Gelatin; Gelatinases; Gene Expression Regulation, Enzymologic; Humans; Ionomycin; Ionophores; Molecular Weight; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Differential control of type-I iodothyronine deiodinase expression by the activation of the cyclic AMP and phosphoinositol signalling pathways in cultured human thyrocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Calcimycin; Calcium; Carcinoma; Cells, Cultured; Cyclic AMP; Dimethyl Sulfoxide; Enzyme Induction; Graves Disease; Humans; Iodide Peroxidase; Microsomes, Liver; Phosphatidylinositols; Proteins; Selenoproteins; Signal Transduction; Sodium Selenite; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyroid Neoplasms; Thyroid Nodule; Thyrotropin | 1995 |
Thapsigargin induces IL-2 receptor alpha-chain in human peripheral and Jurkat T cells via a protein kinase C-independent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Base Sequence; Calcimycin; Calcium; Calcium-Transporting ATPases; Cholera Toxin; Colforsin; Drug Synergism; Gene Expression Regulation; Gene Expression Regulation, Leukemic; Humans; Hydroquinones; Isoquinolines; Leukemia-Lymphoma, Adult T-Cell; Molecular Sequence Data; Neoplasm Proteins; NF-kappa B; Piperazines; Protein Kinase C; Receptors, Interleukin-2; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Staurosporine; T-Lymphocytes; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1995 |
In vitro characterization of Acanthamoeba castellanii cytopathic effect.
Topics: Acanthamoeba; Animals; Bepridil; Calcimycin; Calcium Channels; Cathepsin C; Cell Survival; Cytochalasin D; Cytoskeleton; Cytotoxicity, Immunologic; Dipeptides; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Humans; Immunosuppressive Agents; Killer Cells, Lymphokine-Activated; Melanoma; Microscopy, Electron; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uveal Neoplasms | 1995 |
Mineral fiber-induced leukocyte activation: the role of intra- and extracellular calcium.
Topics: Asbestos, Serpentine; Calcimycin; Calcium; Cell Survival; Dose-Response Relationship, Drug; Egtazic Acid; Fura-2; Humans; Luminescent Measurements; Lymphocyte Activation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Quartz; Reactive Oxygen Species; Respiratory Burst; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Verapamil | 1995 |
Comparison of protein phosphorylation patterns produced in adrenal cells by activation of cAMP-dependent protein kinase and Ca-dependent protein kinase.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Angiotensin II; Animals; Calcimycin; Calcium; Cattle; Cell Compartmentation; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Gel, Two-Dimensional; Enzyme Activation; Hydrocortisone; Phosphoproteins; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1995 |
Regulation of the activity and phosphorylation of the plasma membrane Ca(2+)-ATPase by adriamycin in intact human erythrocytes.
Topics: Calcimycin; Calcium; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Doxorubicin; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Membrane Lipids; Phospholipids; Phosphorylation; Tetradecanoylphorbol Acetate | 1995 |
Glutamate stably enhances the activity of two cytosolic forms of phospholipase A2 in brain cortical cultures.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Cerebral Cortex; Chromatography, Gel; Cytosol; Enzyme Activation; Glutamic Acid; Hydrogen-Ion Concentration; Isoenzymes; Neurons; Phospholipases A; Phospholipases A2; Rats; Tetradecanoylphorbol Acetate | 1995 |
Differential effect of activators of protein kinase C on cytoskeletal changes in mouse and hamster eggs.
Topics: Amino Acid Sequence; Animals; Calcimycin; Cricetinae; Cytoskeleton; Diglycerides; Enzyme Activation; Female; Mesocricetus; Mice; Molecular Sequence Data; Ovum; Peptides; Phorbol Esters; Protamine Kinase; Protein Kinase C; Species Specificity; Substrate Specificity; Tetradecanoylphorbol Acetate | 1995 |
[The damaging effect of activated human neutrophils on isolated perfused rat lungs--the role of elastase].
Topics: Animals; Calcimycin; In Vitro Techniques; Leukocyte Elastase; Lung; Neutrophil Activation; Neutrophils; Pancreatic Elastase; Rats; Tetradecanoylphorbol Acetate | 1995 |
Stimulation by thyroid-stimulating hormone and Grave's immunoglobulin G of vascular endothelial growth factor mRNA expression in human thyroid follicles in vitro and flt mRNA expression in the rat thyroid in vivo.
Topics: Animals; Bucladesine; Calcimycin; Cell Division; Cells, Cultured; Culture Media, Conditioned; DNA Probes; Dose-Response Relationship, Drug; Endothelial Growth Factors; Gene Expression; Graves Disease; Humans; Immunoglobulin G; Insulin; Kinetics; Lymphokines; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiouracil; Thyroid Gland; Thyrotropin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factors | 1995 |
Purification and partial characterization of acrosome reaction inhibiting glycoprotein from human seminal plasma.
Topics: Acrosome; Amidohydrolases; Atrial Natriuretic Factor; Calcimycin; Calcium; Carbohydrate Conformation; Carbohydrates; Diglycerides; Electrophoresis, Polyacrylamide Gel; Exocytosis; Glycoproteins; Glycosylation; Humans; Hydrogen-Ion Concentration; Male; Molecular Weight; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Semen; Spermatozoa; Tetradecanoylphorbol Acetate | 1995 |
Intracellular mechanisms of cytoplasmic Ca2+ oscillation in rat megakaryocyte.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Alkaloids; Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Calmodulin; Colforsin; Cyclic AMP; Cytoplasm; Egtazic Acid; Female; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Megakaryocytes; Models, Biological; Oscillometry; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Trifluoperazine | 1993 |
Comparative in vitro studies on the immunosuppressive effects of purine and pyrimidine synthesis inhibitors.
Topics: Aspartic Acid; Biphenyl Compounds; Calcimycin; Cells, Cultured; Cyclosporine; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Lymphocytes; Mycophenolic Acid; Phosphonoacetic Acid; Ribonucleosides; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Thrombin Ca(2+)-dependently stimulates protein tyrosine phosphorylation in BC3H1 muscle cells.
Topics: Animals; Calcimycin; Calcium; Cell Line; Egtazic Acid; Epidermal Growth Factor; Immunoblotting; Insulin; Kinetics; Mice; Muscles; Pertussis Toxin; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Thrombin; Tyrosine; Virulence Factors, Bordetella | 1993 |
Modulators of protein kinase C inhibit hypoxia-induced erythropoietin production.
Topics: Blotting, Northern; Calcimycin; Carcinoma, Hepatocellular; Diglycerides; DNA; Dose-Response Relationship, Drug; Erythropoietin; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Leucine; Liver Neoplasms; Protein Kinase C; Radioimmunoassay; RNA; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured; Uridine | 1993 |
Effect of a potent selective protein kinase C inhibitor on histamine release from rat mast cells.
Topics: Alkaloids; Animals; Calcimycin; Histamine Release; Immunoglobulin E; In Vitro Techniques; Mast Cells; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Structural and functional changes of exocrine pancreas induced by FK506 in rats.
Topics: Amylases; Analysis of Variance; Animals; Atropine; Body Weight; Calcimycin; Calcium; Carbachol; Cholecystokinin; Colforsin; Cytosol; Dose-Response Relationship, Drug; Feeding Behavior; Kinetics; Male; N-Methylscopolamine; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Reference Values; Scopolamine; Scopolamine Derivatives; Secretin; Sincalide; Tacrolimus; Tetradecanoylphorbol Acetate; Time Factors; Trypsinogen; Vasoactive Intestinal Peptide | 1993 |
Involvement of protein kinase C in agonist-stimulated goldfish ovulation.
Topics: Alkaloids; Animals; Calcimycin; Dinoprost; Female; Goldfish; Hydrogen-Ion Concentration; In Vitro Techniques; Naphthalenes; Ovulation; Polycyclic Compounds; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Vanadates | 1993 |
Pancreatic acini possess endothelin receptors whose internalization is regulated by PLC-activating agents.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Amylases; Animals; Benzodiazepinones; Bombesin; Calcimycin; Carbachol; Cholecystokinin; Cyclic AMP; Devazepide; Endothelins; Enzyme Activation; In Vitro Techniques; Kinetics; Male; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Secretin; Sincalide; Tetradecanoylphorbol Acetate; Type C Phospholipases; Vasoactive Intestinal Peptide | 1993 |
Regulated expression of an intestinal mucin gene in HT29 colonic carcinoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenocarcinoma; Bucladesine; Calcimycin; Colforsin; Colonic Neoplasms; DNA Probes; Ethers, Cyclic; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Ionomycin; Ionophores; Kinetics; Mucins; Okadaic Acid; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Cellular mechanisms for orthovanadate-, phorbol ester-, and calcium ionophore-stimulated prostaglandin production in brook trout (Salvelinus fontinalis) follicles.
Topics: Animals; Arachidonic Acid; Calcimycin; Cycloheximide; Dactinomycin; Female; Hydroxyeicosatetraenoic Acids; Ovarian Follicle; Prostaglandins; Tetradecanoylphorbol Acetate; Tritium; Trout; Vanadates | 1993 |
Analysis of fra-2 gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Base Sequence; Calcimycin; Cells, Cultured; Chick Embryo; Chickens; Chloramphenicol O-Acetyltransferase; Cholera Toxin; Cyclic AMP; Dinucleoside Phosphates; DNA-Binding Proteins; Enhancer Elements, Genetic; Fibroblasts; Fos-Related Antigen-2; Gene Expression Regulation; Genes, fos; Molecular Sequence Data; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Messenger; Sequence Deletion; TATA Box; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection | 1993 |
Regulation of CD59 expression on the human endothelial cell line EA.hy 926.
Topics: Antigens, CD; Bucladesine; Calcimycin; CD59 Antigens; Cell Line; Complement Membrane Attack Complex; Complement System Proteins; Cytokines; Cytotoxicity, Immunologic; Endothelium, Vascular; Gene Expression Regulation; Humans; Membrane Glycoproteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Up-Regulation | 1993 |
Second messenger regulation of lipoprotein uptake by an arterial wall model.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Aorta; Calcimycin; Cattle; Cell Membrane Permeability; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Galanin; GTP-Binding Proteins; Lipid Bilayers; Lipoproteins; Lipoproteins, LDL; Muscle, Smooth, Vascular; Peptides; Pertussis Toxin; Protein Kinase C; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Neurohormonal regulation of histamine release from isolated rabbit fundic mucosal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Carbachol; Colforsin; Diglycerides; Dose-Response Relationship, Drug; Gastric Fundus; Gastric Mucosa; Gastrins; Histamine Release; Male; Muscarinic Antagonists; Prostaglandins; Rabbits; Sincalide; Somatostatin; Tetradecanoylphorbol Acetate | 1993 |
Selection of alternative G-mediated signaling pathways at the dopamine D2 receptor by protein kinase C.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Alkaloids; Animals; Arachidonic Acid; Calcimycin; Calcium; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Diglycerides; Diterpenes; Dopamine D2 Receptor Antagonists; Ergolines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Protein Kinase C; Quinpirole; Raclopride; Receptors, Dopamine D2; Recombinant Proteins; Salicylamides; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Alteration of lipid composition modulates Fc epsilon RI signaling in RBL-2H3 cells.
Topics: Antigens; Arachidonic Acid; Calcimycin; Cell Degranulation; Cell Line; Cell Membrane; Cholesterol; Dinitrophenols; Liposomes; Membrane Lipids; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Phospholipids; Receptors, IgE; Serotonin; Serum Albumin, Bovine; Signal Transduction; Sonication; Sphingomyelins; Tetradecanoylphorbol Acetate; Tritium | 1995 |
Receptor-independent mechanisms are involved in the priming of neutrophil's oxidase by vasoactive intestinal peptide.
Topics: Calcimycin; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophil Activation; Neutrophils; Receptors, Vasoactive Intestinal Peptide; Respiratory Burst; Somatostatin; Sphingosine; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1994 |
Phorbol ester-induced alteration in the pattern of secretion and storage of chromogranin A and neurotensin in a human pancreatic carcinoid cell line.
Topics: Analysis of Variance; Blotting, Northern; Calcimycin; Carcinoid Tumor; Cell Division; Cell Line; Chromogranin A; Chromogranins; Dose-Response Relationship, Drug; Gene Expression; Humans; Ionomycin; Kinetics; Methionine; Neurotensin; Pancreatic Hormones; Pancreatic Neoplasms; Peptide Fragments; RNA, Messenger; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Contrasting effects of calyculin A and okadaic acid on the respiratory burst of human neutrophils.
Topics: Amino Acid Sequence; Calcimycin; Ethers, Cyclic; Humans; In Vitro Techniques; Marine Toxins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Calcium and protein kinase C play an important role in Campylobacter jejuni-induced changes in Na+ and Cl- transport in rat ileum in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Calmodulin; Campylobacter Infections; Campylobacter jejuni; Chlorides; Cyclic AMP; Dantrolene; Diarrhea; Enzyme Activation; Ileum; In Vitro Techniques; Ion Transport; Isoquinolines; Male; Piperazines; Protein Kinase C; Rats; Rats, Wistar; Sodium; Tetradecanoylphorbol Acetate; Verapamil | 1995 |
Arachidonic acid liberation from rat tracheal epithelial cells by alveolar macrophages.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Bronchoalveolar Lavage Fluid; Calcimycin; Cells, Cultured; Culture Media, Conditioned; Epithelium; Inflammation; Macrophages, Alveolar; Rats; Tetradecanoylphorbol Acetate; Trachea | 1995 |
AA-release is under control of PLA2 and DAG lipase in rat liver macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Cyclohexanones; Fluorides; Isoenzymes; Kinetics; Kupffer Cells; Lipoprotein Lipase; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Zymosan | 1995 |
Protein kinase C-independent inhibition of the Ca(2+)-activated K+ channel by angiotensin II and endothelin-1.
Topics: Alkaloids; Angiotensin II; Animals; Calcimycin; Cells, Cultured; Coronary Vessels; Endothelins; Large-Conductance Calcium-Activated Potassium Channels; Membrane Proteins; Muscle, Smooth, Vascular; Neomycin; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Protein Kinase C; Staurosporine; Swine; Tetradecanoylphorbol Acetate | 1995 |
Bradykinin and Met-T-kinin-Leu stimulated PGE2 production by rat macrophage and fibroblast.
Topics: Animals; Bradykinin; Calcimycin; Cells, Cultured; Dinoprostone; Fibroblasts; Macrophages; Rats; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Interactions between second messenger pathways influence NGF synthesis in mouse primary astrocytes.
Topics: Animals; Astrocytes; Blood Physiological Phenomena; Calcimycin; Cells, Cultured; Colforsin; Mice; Mice, Inbred Strains; Nerve Growth Factors; Proto-Oncogene Proteins; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1995 |
Specificity of phospholipase D activation by cholecystokinin and phorbol myristate acetate but not by carbamylcholine and A23187 in rat pancreatic acini.
Topics: Alkaloids; Animals; Calcimycin; Carbachol; Ceruletide; Cholecystokinin; Choline; Egtazic Acid; Enzyme Activation; Glycerophospholipids; In Vitro Techniques; Male; Pancreas; Phosphatidic Acids; Phospholipase D; Phosphorylcholine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1995 |
Effect of lipoproteins on macrophage superoxide generation.
Topics: Animals; Arachidonic Acid; Calcimycin; Digitonin; Humans; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Macrophages, Peritoneal; Neutrophils; Rats; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Chemoattractants induce rapid release of the interleukin 1 type II decoy receptor in human polymorphonuclear cells.
Topics: Amino Acid Sequence; Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Humans; In Vitro Techniques; Interleukin-1; Interleukin-8; Leukotriene B4; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Receptors, Interleukin-1; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1995 |
Role of Ca2+ and calmodulin in ehrlichial infection in macrophages.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Ehrlichia; Energy Metabolism; Female; Gallic Acid; Macrophages; Mice; Nitrites; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate | 1995 |
In vitro inhibition of murine IFN gamma production by phosphorothioate deoxyguanosine oligomers.
Topics: Animals; Calcimycin; Cells, Cultured; Concanavalin A; Deoxyguanosine; DNA, Bacterial; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Female; Interferon-gamma; Mice; Mice, Inbred BALB C; Oligodeoxyribonucleotides; Polymers; Spleen; Tetradecanoylphorbol Acetate; Thionucleotides | 1995 |
Characterization of the human interleukin-5 gene promoter: involvement of octamer binding sites in the gene promoter activity.
Topics: Animals; Base Sequence; Binding Sites; Bucladesine; Calcimycin; Consensus Sequence; Gene Expression Regulation; Genes; Genes, Reporter; Humans; Interleukin-5; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Point Mutation; Promoter Regions, Genetic; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription Factors; Transfection; Tumor Cells, Cultured | 1995 |
Heparan sulfate proteoglycan and control of cell proliferation: enhanced synthesis induced by phorbol ester (PMA) during G(1)-phase.
Topics: Animals; Calcimycin; Cell Division; Cell Line; Endothelium, Vascular; G1 Phase; Glycosaminoglycans; Heparan Sulfate Proteoglycans; Heparitin Sulfate; Proteoglycans; Rabbits; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
TGF-beta 1 augments expression of the TIS10/prostaglandin synthase-2 gene in intestinal epithelial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blotting, Northern; Calcimycin; Cell Line; Cyclooxygenase 2; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction; Epithelium; Gene Expression; Intestines; Kinetics; Prostaglandin-Endoperoxide Synthases; Rats; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta | 1994 |
Differential regulation of sympathetic neuron neuropeptide Y and catecholamine content and secretion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Bucladesine; Calcimycin; Catecholamines; Cells, Cultured; Colforsin; Dopamine; Electrochemistry; Female; Homeostasis; Homovanillic Acid; Immunohistochemistry; Kinetics; Neurons; Neuropeptide Y; Potassium; Pregnancy; Rats; Rats, Sprague-Dawley; Signal Transduction; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Mode of action of an inhibitory neuropeptide SchistoFLRFamide on the locust oviduct visceral muscle.
Topics: Amino Acid Sequence; Animals; Caffeine; Calcimycin; Calcium; Calcium Channels; Cobalt; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Female; Grasshoppers; Ion Channel Gating; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neuropeptides; Nifedipine; Oviducts; Tetradecanoylphorbol Acetate | 1995 |
Endothelin-1 modulates renin and prolactin release from human decidua by different mechanisms.
Topics: Alkaloids; Calcimycin; Decidua; Endothelins; Female; Humans; Nifedipine; Prolactin; Renin; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
N-ethylmaleimide inhibits platelet aggregation and potentiates hydrogen peroxide formation induced by thrombin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arachidonic Acid; Blood Platelets; Calcimycin; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Ethylmaleimide; Humans; Hydrogen Peroxide; Platelet Activation; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Vasoconstrictor Agents | 1994 |
Calpain expression in lymphoid cells. Increased mRNA and protein levels after cell activation.
Topics: Blood; Calcimycin; Calpain; Cell Line; Cycloheximide; Dexamethasone; Dichlororibofuranosylbenzimidazole; Gene Expression Regulation; Humans; Interferon-gamma; Lymphocyte Activation; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Calcium ionophore A23187 inhibits ACTH secretion from a human small cell lung cancer cell line, COR-L103.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Calcimycin; Carcinoma, Small Cell; Cell Line; Corticotropin-Releasing Hormone; Dexamethasone; Dose-Response Relationship, Drug; Humans; Immunoradiometric Assay; Interleukin-1; Interleukin-2; Kinetics; Lung Neoplasms; Pro-Opiomelanocortin; Somatostatin; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1995 |
Comparative regulation of inhibin, activin and human chorionic gonadotropin production by placental trophoblast cells in culture.
Topics: Activins; Blotting, Western; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Culture Media, Conditioned; Cyclic AMP; Dexamethasone; Enzyme Activation; Epinephrine; Female; Gonadotropin-Releasing Hormone; Humans; Inhibins; Pregnancy; Protein Kinase C; Tetradecanoylphorbol Acetate; Trophoblasts | 1994 |
Calcium mobilization and protein kinase C activation are required for cholecystokinin stimulation of pancreatic cholesterol esterase secretion.
Topics: Animals; Calcimycin; Calcium; Cholecystokinin; Egtazic Acid; Enzyme Activation; Pancreas; Pancreatic Neoplasms; Protein Kinase C; Rats; Sterol Esterase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Effects of second messengers on the permeability and morphology of eel rete capillaries.
Topics: Albumins; Animals; Bucladesine; Calcimycin; Calcium; Capillaries; Capillary Permeability; Colforsin; Diglycerides; Eels; Isoproterenol; Microscopy, Electron; Nucleotides, Cyclic; Phosphatidylinositols; Second Messenger Systems; Sodium; Sucrose; Tetradecanoylphorbol Acetate | 1995 |
Activation of the transcription factor NF-KB in GH3 pituitary cells.
Topics: Base Sequence; Binding Sites; Calcimycin; Cell Line; Cell Nucleus; DNA; Molecular Sequence Data; NF-kappa B; Oligonucleotide Probes; Pituitary Gland; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Necrosis Factor-alpha | 1994 |
Commitment to lymphokine profile during primary in vitro stimulation.
Topics: Animals; Calcimycin; CD3 Complex; CD4-Positive T-Lymphocytes; Cells, Cultured; Enterotoxins; Female; Interleukin-4; Lymphocyte Activation; Lymphokines; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Staphylococcus aureus; Tetradecanoylphorbol Acetate | 1993 |
Factor XIIIa binding to activated platelets is mediated through activation of glycoprotein IIb-IIIa.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Antibodies, Monoclonal; Antigens, CD; Arachidonic Acid; Blood Platelets; Calcimycin; Collagen; Epinephrine; Fibrinogen; Fibronectins; Flow Cytometry; Humans; In Vitro Techniques; Kinetics; Membrane Glycoproteins; Membrane Proteins; Oligopeptides; Platelet Activation; Platelet Membrane Glycoproteins; Reference Values; Tetradecanoylphorbol Acetate; Thrombasthenia; Thrombin; Thrombospondins; Time Factors; Transglutaminases | 1994 |
Remodeling of neutrophil phospholipids with 15(S)-hydroxyeicosatetraenoic acid inhibits leukotriene B4-induced neutrophil migration across endothelium.
Topics: Antigens, CD; Calcimycin; CD11 Antigens; CD18 Antigens; Cells, Cultured; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipids; Receptors, Leukocyte-Adhesion; Tetradecanoylphorbol Acetate; Umbilical Veins | 1994 |
The phorbol ester TPA potentiates cholera toxin- and isoproterenol-stimulated cyclic AMP-synthesis in primary astrocyte cultures.
Topics: Adrenergic beta-Agonists; Animals; Animals, Newborn; Astrocytes; Calcimycin; Cells, Cultured; Cholera Toxin; Cyclic AMP; Drug Synergism; Isoproterenol; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1994 |
The regulation of interleukin 5 and interleukin 3 gene expression in human T cells.
Topics: Base Sequence; Calcimycin; CD4-Positive T-Lymphocytes; Concanavalin A; Cycloheximide; Cyclosporine; DNA Primers; Gene Expression Regulation; Humans; Interleukin-3; Interleukin-5; Lymphocyte Activation; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger; T-Lymphocyte Subsets; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1994 |
Release and steroidogenic actions of polyunsaturated fatty acids in the goldfish testis.
Topics: Animals; Arachidonic Acid; Calcimycin; Dinoprostone; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Goldfish; Indomethacin; Male; Prostaglandins E; Testis; Testosterone; Tetradecanoylphorbol Acetate | 1994 |
Phorbol esters impair endothelium-dependent and independent relaxation in rat aortic rings.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcimycin; Endothelium, Vascular; Enzyme Activation; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1994 |
Vasoactive intestinal peptide inhibits interleukin (IL)-2 and IL-4 production in murine thymocytes activated via the TCR/CD3 complex.
Topics: Animals; Antibodies; Calcimycin; CD3 Complex; Cell Division; Cyclic AMP; Female; Interleukin-2; Interleukin-4; Mice; Mice, Inbred BALB C; Receptors, Antigen, T-Cell; Tetradecanoylphorbol Acetate; Thymus Gland; Time Factors; Vasoactive Intestinal Peptide | 1994 |
What is the dose-response curve for the effects of cyclosporine on calcineurin and cytokine induction in vivo?
Topics: Animals; Calcimycin; Calcineurin; Calmodulin-Binding Proteins; Cells, Cultured; Cyclosporine; Cytokines; Dose-Response Relationship, Drug; Gene Expression; Humans; Interferon-gamma; Interleukin-2; Lymphocytes; Mice; Phosphoprotein Phosphatases; RNA, Messenger; Signal Transduction; Spleen; Tetradecanoylphorbol Acetate | 1994 |
Tumor necrosis factor-alpha decreases pulmonary artery endothelial nitrovasodilator via protein kinase C.
Topics: Animals; Arginine; Calcimycin; Cattle; Endothelium, Vascular; Nitrites; Nitro Compounds; Nitroso Compounds; omega-N-Methylarginine; Peroxides; Protein Kinase C; Pulmonary Artery; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vasodilator Agents | 1994 |
[The role of phospholipase A2, 5-lipoxygenase, and cyclooxygenase in activation of human neutrophil "oxygen burst": the modulating effect of osmolality of the medium].
Topics: Acetophenones; Arachidonate 5-Lipoxygenase; Calcimycin; Humans; Lipoxygenase Inhibitors; Meclofenamic Acid; Neutrophils; Osmolar Concentration; Oxygen; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Quercetin; Respiratory Burst; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Alkaloids; Animals; Bucladesine; Calcimycin; Calmodulin; Cell Line; Colforsin; Culture Media; Cytoplasm; Dyneins; Edetic Acid; Ethers, Cyclic; Imidazoles; Kidney; Kinetics; Macromolecular Substances; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorus Radioisotopes; Phosphorylation; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate | 1994 |
Enhancement of mouse egg activation by the kinase inhibitor, 6-dimethylaminopurine (6-DMAP).
Topics: Adenine; Animals; Calcimycin; Cycloheximide; Female; Interphase; Maturation-Promoting Factor; Mesothelin; Metaphase; Mice; Ovum; Phosphotransferases; Proto-Oncogene Proteins c-mos; Tetradecanoylphorbol Acetate | 1994 |
Stimulation of intercellular adhesion molecule-1 (ICAM-1) antigen expression and shedding by interferon-gamma and phorbol ester in human renal carcinoma cell cultures: relation to peripheral blood mononuclear cell adhesion.
Topics: Antigens, Neoplasm; Calcimycin; Carcinoma, Renal Cell; Cell Adhesion; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Kidney Neoplasms; Leukocytes, Mononuclear; Lymphocyte Function-Associated Antigen-1; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Agents that increase phosphatidic acid inhibit the LH-induced testosterone production.
Topics: Animals; Bucladesine; Calcimycin; Cholesterol Side-Chain Cleavage Enzyme; Cyclic AMP; Leydig Cells; Luteinizing Hormone; Male; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phospholipase D; Propranolol; Rats; Rats, Sprague-Dawley; Sphingosine; Testosterone; Tetradecanoylphorbol Acetate | 1994 |
Regulation of cytosolic phospholipase A2 phosphorylation and eicosanoid production by colony-stimulating factor 1.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cytosol; Drug Synergism; Eicosanoids; Enzyme Activation; Macrophage Colony-Stimulating Factor; Macrophages, Peritoneal; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Prostaglandin F2 alpha stimulates progesterone secretion by porcine luteal cells in vitro throughout the estrous cycle.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Calcimycin; Cells, Cultured; Corpus Luteum; Dihydrotestosterone; Dinoprost; Dose-Response Relationship, Drug; Estrus; Female; Pregnancy; Progesterone; Radioimmunoassay; Swine; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
1,3-Dioctanoylglycerol (1,3-DiC8) is as effective as 1,2-dioctanoylglycerol (1,2-DiC8) in priming phospholipase A2 activation in human platelets and neutrophils.
Topics: Arachidonic Acid; Blood Platelets; Calcimycin; Diglycerides; Enzyme Activation; Humans; Neutrophils; Phospholipases A; Phospholipases A1; Phospholipases A2; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
Intracellular mediators of goblet cell degranulation in isolated pancreatic ducts.
Topics: Animals; Calcimycin; Carbachol; Cell Degranulation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytochalasin D; Dichlororibofuranosylbenzimidazole; Enzyme Activation; Ethers, Cyclic; Guinea Pigs; In Vitro Techniques; Male; Nocodazole; Okadaic Acid; Pancreatic Ducts; Protein Kinase C; Tetradecanoylphorbol Acetate; Thionucleotides; Vasoactive Intestinal Peptide | 1994 |
Phospholipid peroxidation in tumor promoter-exposed mouse skin.
Topics: Aminobenzoates; Animals; Antioxidants; Borohydrides; Calcimycin; Chlorobenzoates; Chromatography, High Pressure Liquid; Cinnamates; Epidermis; Female; Fluocinolone Acetonide; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydrolysis; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxidation; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred SENCAR; ortho-Aminobenzoates; Phospholipases A; Phospholipases A2; Phospholipids; Pregnatrienes; Stereoisomerism; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances | 1994 |
Prostaglandin E2/parathyroid hormone-induced suppression of alkaline phosphatase activity is mediated by protein kinase C.
Topics: Alkaline Phosphatase; Alkaloids; Animals; Bucladesine; Calcimycin; Cyclic AMP; Cycloheximide; Dinoprostone; Isoquinolines; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Protein Kinase C; Rats; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Cyclosporin A enhances cytokine and phorbol ester-induced fibroblast collagenase expression.
Topics: Blotting, Northern; Calcimycin; Cell Line; Collagenases; Cyclosporine; Cytokines; Dose-Response Relationship, Drug; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Gene Expression Regulation, Enzymologic; Genes, jun; Humans; Interleukin-1; Lung; Phorbol Esters; Proto-Oncogene Proteins c-jun; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Effects of prostaglandin E2 on Th0-type human T cell clones: modulation of functions of nuclear proteins involved in cytokine production.
Topics: Base Sequence; Calcimycin; CD3 Complex; Cell Line; Cyclic AMP; Cytokines; Dinoprostone; Humans; Interleukin-4; Interleukin-5; Lymphocyte Activation; Molecular Sequence Data; NF-kappa B; Nuclear Proteins; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1994 |
Activation of protein kinase C down-regulates leukotriene C4 synthase activity and attenuates cysteinyl leukotriene production in an eosinophilic substrain of HL-60 cells.
Topics: Alkaloids; Calcimycin; Cysteine; Down-Regulation; Eosinophils; Glutathione Transferase; Humans; Leukemia, Promyelocytic, Acute; Leukotrienes; Nitriles; Phenols; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrphostins | 1994 |
Dependence of thymocyte apoptosis on protein kinase C and phospholipase A2.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Calcimycin; Concanavalin A; DNA; Enzyme Activation; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Phospholipases A; Phospholipases A2; Piperazines; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thymus Gland | 1994 |
Calcium-dependent regulation of rat and chick muscle nicotinic acetylcholine receptor (nAChR) gene expression.
Topics: Animals; Base Sequence; Calcimycin; Calcium; Cells, Cultured; Chick Embryo; Gene Expression Regulation; Molecular Sequence Data; Muscle Development; Muscles; Neuromuscular Junction; Promoter Regions, Genetic; Protein Kinase C; Rats; Receptors, Nicotinic; Recombinant Proteins; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tissue Distribution; Transcription, Genetic | 1994 |
Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Ethers, Cyclic; Gene Expression Regulation, Enzymologic; Indoles; Isoenzymes; Macrophages, Peritoneal; Maleimides; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Zymosan | 1994 |
Molecular cloning of a novel human cDNA encoding a zinc finger protein that binds to the interleukin-3 promoter.
Topics: Amino Acid Sequence; Base Sequence; Calcimycin; Cell Line; Cloning, Molecular; DNA-Binding Proteins; DNA, Complementary; Early Growth Response Protein 1; Early Growth Response Protein 2; Gene Expression Regulation; Gene Products, tax; Humans; Immediate-Early Proteins; Interleukin-3; Macromolecular Substances; Molecular Sequence Data; Oligodeoxyribonucleotides; Promoter Regions, Genetic; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Distribution; Transcription Factors; Transcription, Genetic; Zinc Fingers | 1994 |
Dephosphorylation of cofilin in stimulated platelets: roles for a GTP-binding protein and Ca2+.
Topics: Actin Depolymerizing Factors; Amino Acid Sequence; Blood Platelets; Calcimycin; Calcium; GTP-Binding Proteins; Humans; In Vitro Techniques; Microfilament Proteins; Molecular Sequence Data; Nerve Tissue Proteins; Phosphorylation; Platelet Aggregation; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1994 |
Melittin inhibits epidermal growth factor-induced protein tyrosine phosphorylation: comparison with phorbol myristate acetate and calcium ionophore A23187.
Topics: 3T3 Cells; Animals; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Dimethyl Sulfoxide; Epidermal Growth Factor; Melitten; Mice; Phosphorylation; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Differential effects of phorbol 12-myristate 13-acetate and diacylglycerols on thromboxane A2-independent phospholipase A2 activation in collage-stimulated human platelets.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Blood Platelets; Calcimycin; Calcium; Collagen; Diglycerides; Enzyme Activation; Humans; Phospholipases A; Phospholipases A1; Phospholipases A2; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1994 |
Priming effect of hydroxyapatite on the chemiluminescence response in human polymorphonuclear leukocytes.
Topics: Calcimycin; Dose-Response Relationship, Drug; Durapatite; Humans; Inflammation; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sodium Fluoride; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1994 |
[Effect of osmolarity of the medium on the chemiluminescence of human neutrophils].
Topics: Calcimycin; Hot Temperature; Humans; Immunoglobulin G; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Oxygen; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Phorbol ester-induced activation of a membrane-bound candidate pro-transforming growth factor-alpha processing enzyme.
Topics: Amino Acid Sequence; Animals; Calcimycin; Cell Membrane; CHO Cells; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cricetinae; Endopeptidases; Enzyme Activation; Molecular Sequence Data; Protein Processing, Post-Translational; Serine Endopeptidases; Subcellular Fractions; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1994 |
A mechanism for phorbol ester-mediated regulation of the PAF receptor in human neutrophils.
Topics: Calcimycin; Calcium; Cytochalasin B; Down-Regulation; Egtazic Acid; Humans; In Vitro Techniques; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1994 |
Effect of intracellular Ca2+ concentration on endothelin-1 secretion.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Endothelins; Endothelium, Vascular; Ionomycin; L-Lactate Dehydrogenase; Swine; Tetradecanoylphorbol Acetate | 1994 |
Cortisol inhibition of growth hormone-releasing hormone-stimulated growth hormone release from cultured sheep pituitary cells.
Topics: Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cells, Cultured; Colforsin; Depression, Chemical; Growth Hormone; Growth Hormone-Releasing Hormone; Hydrocortisone; Male; Pertussis Toxin; Pituitary Gland; Potassium Chloride; Puromycin; Sheep; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1994 |
Separation of agonist-stimulated arachidonate mobilization from subsequent leukotriene B4 synthesis in human neutrophils: different effects of oleoylacetylglycerol and phorbol myristate acetate as priming agents.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Arachidonic Acid; Biological Transport; Calcimycin; Diglycerides; Eicosanoids; Fatty Acids; Humans; Hydroxyeicosatetraenoic Acids; Indoles; Leukotriene Antagonists; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Tetradecanoylphorbol Acetate | 1994 |
Calcium overload toxicity and functional impairment in peritoneal leukocytes elicited by glycogen or interleukin-1 beta.
Topics: Animals; Calcimycin; Calcium; Drug Synergism; Glucuronidase; Glycogen; Humans; Injections, Intraperitoneal; Interleukin-1; L-Lactate Dehydrogenase; Leukocytes; Leukotrienes; Male; N-Formylmethionine Leucyl-Phenylalanine; Rats; Rats, Wistar; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Complement activation and neutrophil aggregation changes during haemodialysis.
Topics: Acrylic Resins; Adult; Arachidonic Acid; Calcimycin; Cell Aggregation; Cellulose; Complement Activation; Humans; Kidney Failure, Chronic; Membranes, Artificial; Middle Aged; Neutrophils; Renal Dialysis; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2 | 1993 |
Comparison of the effects of tumour necrosis factor alpha stimulation and phorbol ester treatment on the immunocytochemical staining of intercellular adhesion molecule 1 in human renal carcinoma cell cultures.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Calcimycin; Carcinoma, Renal Cell; Cell Adhesion Molecules; Humans; Immunoenzyme Techniques; Intercellular Adhesion Molecule-1; Isoquinolines; Kidney Neoplasms; Piperazines; Protein Kinase C; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1993 |
Phorbol ester-induced degranulation in adherent human eosinophil granulocytes is dependent on CD11/CD18 leukocyte integrins.
Topics: Antibodies; Antigens, CD; Blood Proteins; Calcimycin; CD11 Antigens; CD18 Antigens; Cell Adhesion; Cell Degranulation; Chelating Agents; Cytochalasin B; Egtazic Acid; Eosinophil Granule Proteins; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Integrins; Interleukin-3; Ionomycin; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Phorbol Esters; Protein Kinase C; Ribonucleases; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Role of protein kinase C during interferon-gamma- and phorbol ester-stimulated immunocytochemical expression of ICAM-1 in human renal carcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Antigens, CD; Calcimycin; Carcinoma, Renal Cell; Cell Adhesion Molecules; Dose-Response Relationship, Drug; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interferon-gamma; Isoquinolines; Kidney Neoplasms; Piperazines; Protein Kinase C; Recombinant Proteins; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Ultraviolet B injury increases prostaglandin synthesis through a tyrosine kinase-dependent pathway. Evidence for UVB-induced epidermal growth factor receptor activation.
Topics: Calcimycin; Catechols; Cells, Cultured; Dinoprostone; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Female; Genistein; Humans; Isoflavones; Keratinocytes; Kinetics; Nitriles; Protein-Tyrosine Kinases; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Tyrphostins; Ultraviolet Rays | 1994 |
Impaired surface expression of PAF receptors on human neutrophils is dependent upon cell activation.
Topics: Calcimycin; Calcium; Cell Aggregation; Cell Membrane; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1994 |
Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles.
Topics: Base Sequence; Binding Sites; Calcimycin; Cell Line; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclosporine; DNA-Binding Proteins; Gene Expression; Interleukin-2; Kinetics; NF-kappa B; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1994 |
Suppression of rat thyrotroph and thyroid cell function by tumor necrosis factor-alpha.
Topics: Animals; Calcimycin; Cell Line; Cyclic AMP-Dependent Protein Kinases; Humans; Interferon-gamma; Interleukin-1; Iodides; Iodine Radioisotopes; Male; Protein Kinase C; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Tumor Necrosis Factor-alpha | 1993 |
Activation of serum response element-regulated genes by lysophosphatidic acid.
Topics: Animals; Blood; Calcimycin; Cell Line; Gene Expression Regulation; Genes, fos; In Vitro Techniques; Lysophospholipids; Promoter Regions, Genetic; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Regulation by glucagon of serine: pyruvate/alanine: glyoxylate aminotransferase gene expression in cultured rat hepatocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alanine Transaminase; Animals; Calcimycin; Cells, Cultured; Cycloheximide; Dexamethasone; Enzyme Induction; Gene Expression; Glucagon; In Vitro Techniques; Liver; Male; Promoter Regions, Genetic; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate; Transaminases; Transcription, Genetic | 1994 |
IL-1 and transforming growth factor-beta regulation of fibroblast-derived IL-11.
Topics: Calcimycin; Cell Line; Fibroblasts; Humans; Interleukin-1; Interleukin-11; Ouabain; Recombinant Proteins; RNA, Messenger; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta | 1994 |
Cefdinir (CI-983), a new oral amino-2-thiazolyl cephalosporin, inhibits human neutrophil myeloperoxidase in the extracellular medium but not the phagolysosome.
Topics: Blood Bactericidal Activity; Calcimycin; Cefdinir; Cell Degranulation; Cephalosporins; Cytochalasin B; Extracellular Space; Humans; Hydrogen Peroxide; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Phagosomes; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Calcineurin activates transcription from the GM-CSF promoter in synergy with either protein kinase C or NF-kappa B/AP-1 in T cells.
Topics: Animals; Base Sequence; Calcimycin; Calcineurin; Calmodulin-Binding Proteins; Cell Line; Coleoptera; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, T-Cell; Luciferases; Mice; Models, Genetic; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Phosphoprotein Phosphatases; Plasmids; Promoter Regions, Genetic; Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; T-Lymphocytes; TATA Box; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1994 |
Characterization of NF(P), the nuclear factor that interacts with the regulatory P sequence (5'-CGAAAATTTCC-3') of the human interleukin-4 gene: relationship to NF-kappa B and NF-AT.
Topics: Base Sequence; Binding Sites; Calcimycin; Cell Line; DNA; DNA-Binding Proteins; Humans; Interleukin-4; Luciferases; Molecular Sequence Data; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Oligodeoxyribonucleotides; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Substrate Specificity; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1994 |
Immunosuppression induced by Salmonella involves inhibition of tyrosine phosphorylation in murine T lymphocytes.
Topics: Animals; Calcimycin; Immune Tolerance; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Phosphorylation; Protein Kinase C; Salmonella Infections, Animal; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine | 1993 |
Protein kinase C is crucial for the stimulation of sodium-dependent phosphate transport by parathyroid hormone-related peptide in osteoblast-like cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenylyl Cyclases; Animals; Biological Transport; Bone Neoplasms; Calcimycin; Calcium; Cell Line; Colforsin; Cytosol; Humans; Isoquinolines; Kinetics; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Phosphates; Piperazines; Protein Kinase C; Proteins; Rats; Sodium; Tetradecanoylphorbol Acetate | 1994 |
Cyclosporin A antagonizes phenylephrine, oxytocin and angiotensin effects on glucose metabolism in rat thymus lymphocytes.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcimycin; Cyclosporine; Dose-Response Relationship, Drug; Fructosediphosphates; Glucose; Glycolysis; Lactates; Lactic Acid; Lymphocytes; Male; Oxytocin; Phenylephrine; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thymus Gland | 1994 |
Polarised interleukin 8 secretion by HT 29/19A cells.
Topics: Calcimycin; Cells, Cultured; Endotoxins; Humans; Interleukin-1; Interleukin-8; Intestinal Mucosa; Ionomycin; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
The development of age-related deficits in several presynaptic processes associated with brain [3H]acetylcholine release.
Topics: Acetylcholine; Aging; Animals; Brain; Calcimycin; Calcium; Cerebral Cortex; Chloramphenicol O-Acetyltransferase; In Vitro Techniques; Male; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Veratridine; Visual Cortex | 1993 |
Schistosoma mansoni: myogenic characteristics of phorbol ester-induced muscle contraction.
Topics: Acetylcholine; Animals; Cadmium; Calcimycin; Calcium; Calcium Channels; Carbachol; Cell Membrane Permeability; Dose-Response Relationship, Drug; Electromyography; Hydrogen-Ion Concentration; Male; Membrane Potentials; Microelectrodes; Muscle Contraction; Nicardipine; Phorbol 12,13-Dibutyrate; Praziquantel; Protein Kinase C; Schistosoma mansoni; Serotonin; Sodium; Tetradecanoylphorbol Acetate | 1994 |
Modulation of dopamine-induced cAMP production in rat striatal cultures by the calcium ionophore A23187 and by phorbol-12-myristate-13-acetate.
Topics: Animals; Calcimycin; Cells, Cultured; Corpus Striatum; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Kinetics; Neurons; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1994 |
Alteration of cell cycle kinetics and immunoglobulin gene transcription as the result of multiple agonist stimulation of murine B cells.
Topics: Animals; B-Lymphocytes; Calcimycin; Cell Cycle; Cell Differentiation; Dextran Sulfate; Female; Genes, Immunoglobulin; Immunoglobulin M; Immunoglobulin mu-Chains; Lipopolysaccharides; Mice; Mice, Inbred BALB C; RNA, Messenger; Spleen; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Production of prostanoids by Lewis rat Schwann cells in vitro.
Topics: Animals; Calcimycin; Cells, Cultured; Dinoprostone; Half-Life; Interferon-gamma; Rats; Rats, Inbred Lew; Schwann Cells; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Tumor Necrosis Factor-alpha | 1994 |
Effects of activators of different intracellular signaling pathways on steroid production by goldfish vitellogenic ovarian follicles.
Topics: Animals; Calcimycin; Calcium; Chorionic Gonadotropin; Cyclic AMP; Drug Synergism; Enzyme Activation; Estradiol; Female; Goldfish; Ovarian Follicle; Protein Kinase C; Signal Transduction; Steroids; Testosterone; Tetradecanoylphorbol Acetate; Vitellogenesis | 1994 |
Phorbol ester-induced transcription of an immediate-early response gene by human T cells is inhibited by co-treatment with calcium ionophore.
Topics: Base Sequence; Calcimycin; Cell Line; Genes, Immediate-Early; Genes, jun; Humans; Molecular Sequence Data; Sequence Homology, Nucleic Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1994 |
[Regulation of aromatase in human choriocarcinoma cells].
Topics: Aromatase; Calcimycin; Cholera Toxin; Choriocarcinoma; Chorionic Gonadotropin; Cytochrome P-450 Enzyme System; Enzyme-Linked Immunosorbent Assay; Female; Humans; Pregnancy; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uterine Neoplasms | 1994 |
Regulation of steroid production in ovarian stromal tissue from 5- to 8-week-old pullets and laying hens.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androstenedione; Animals; Calcimycin; Cells, Cultured; Chickens; Colforsin; Estradiol; Female; Gonadal Steroid Hormones; Luteinizing Hormone; Ovary; Progesterone; Sexual Maturation; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1994 |
Identification of beta-actin sequences necessary for induction by phorbol esters and calcium ionophores.
Topics: Actins; Base Sequence; Calcimycin; Gene Expression Regulation; Genes, fos; Molecular Sequence Data; Nuclear Proteins; Protein Kinase C; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1994 |
Phospholipases and melatonin signal transduction in the ovine pars tuberalis.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Choline; Colforsin; Cyclic AMP; Female; Lysophospholipids; Male; Melatonin; Membrane Lipids; Phosphatidic Acids; Phospholipases; Phospholipids; Pituitary Gland, Anterior; Second Messenger Systems; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Protein kinase C-dependent regulation of sulfidopeptide leukotriene biosynthesis and leukotriene C4 synthase in neutrophilic HL-60 cells.
Topics: Alkaloids; Amino Acid Sequence; Calcimycin; Cell Line; Glutathione Transferase; Humans; Leukotriene A4; Leukotriene B4; Leukotriene C4; Leukotriene D4; Molecular Sequence Data; Neutrophils; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Platelets from bleeding Simmental cattle mobilize calcium, phosphorylate myosin light chain and bind normal numbers of fibrinogen molecules but have abnormal cytoskeletal assembly and aggregation in response to ADP.
Topics: Adenosine Diphosphate; Animals; Blood Coagulation Disorders; Blood Platelets; Calcimycin; Calcium; Cattle; Cattle Diseases; Cytoskeleton; Cytosol; Fibrinogen; In Vitro Techniques; Ionomycin; Male; Microscopy, Electron; Myosins; Phosphorylation; Platelet Aggregation; Platelet Membrane Glycoproteins; Tetradecanoylphorbol Acetate | 1994 |
Regulation of type 1 angiotensin II receptor messenger ribonucleic acid expression in human adrenocortical carcinoma H295 cells.
Topics: Adrenal Cortex Neoplasms; Angiotensin II; Base Sequence; Bucladesine; Calcimycin; Colforsin; Cyclic AMP; Cycloheximide; Gene Expression Regulation, Neoplastic; Humans; Kinetics; Molecular Sequence Data; Phosphoric Diester Hydrolases; Receptors, Angiotensin; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Differential regulation of M-CSF and IL-6 gene expression in monocytic cells.
Topics: Bucladesine; Calcimycin; Cell Line; Gene Expression Regulation; Humans; Interleukin-6; Macrophage Colony-Stimulating Factor; Monocytes; RNA, Messenger; Tetradecanoylphorbol Acetate | 1994 |
Enhancement of natural killer cell activity in septic shock patients by a mixture of the calcium ionophore A23187 and the phorbol ester TPA: in vitro studies.
Topics: Adult; Calcimycin; Drug Combinations; Female; Humans; Immunophenotyping; Killer Cells, Natural; Male; Middle Aged; Shock, Septic; Tetradecanoylphorbol Acetate | 1994 |
JNK is involved in signal integration during costimulation of T lymphocytes.
Topics: Animals; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclosporine; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Lymphocyte Activation; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-jun; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1994 |
Transcriptional regulation of the TCA3 gene in mast cells after Fc epsilon RI cross-linking.
Topics: Base Sequence; Calcimycin; Calcium; Cell Line; Chemokine CCL1; Chemokines, CC; Consensus Sequence; Cytokines; Gene Expression Regulation; Genes; Mast Cells; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Receptor Aggregation; Receptors, IgE; RNA, Messenger; Sequence Alignment; Sequence Deletion; Sequence Homology, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Proliferative responses of peripheral blood lymphocytes of mice and humans stimulated with recombinant interleukin 2.
Topics: Animals; Calcimycin; Cells, Cultured; Drug Interactions; Female; Humans; Interleukin-2; Ionomycin; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Recombinant Proteins; Species Specificity; Tetradecanoylphorbol Acetate | 1993 |
Stimulation of phospholipase-D in Epstein Barr virus-transformed human B-cells.
Topics: B-Lymphocytes; Calcimycin; Cell Line, Transformed; Cell Transformation, Viral; Herpesvirus 4, Human; Humans; Immunoglobulin M; Kinetics; Phospholipase D; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate | 1993 |
Ethanol-specific impairment of T-lymphocyte activation is caused by a transitory block in signal-transduction pathways.
Topics: Adult; Antigen-Presenting Cells; Antigens, CD; Calcimycin; Calcium; Cells, Cultured; Ethanol; Female; Humans; Inositol 1,4,5-Trisphosphate; Interleukin-1; Interleukin-2; Liver Diseases, Alcoholic; Lymphocyte Activation; Male; Middle Aged; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1993 |
Role of dual signal transduction systems in the stimulation of bone resorption by parathyroid hormone-related peptide. The direct involvement of cAMP-dependent protein kinase.
Topics: Animals; Bone Resorption; Calcimycin; Calcitonin; Calcium; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dentin; Humans; In Vitro Techniques; Mice; Mice, Inbred ICR; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Protein Kinase C; Proteins; Signal Transduction; Teriparatide; Tetradecanoylphorbol Acetate | 1993 |
Regulation of phospholipase A2 activation by phosphorylation in mouse peritoneal macrophages.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Enzyme Activation; Ethers, Cyclic; Macrophages; Mice; Molecular Sequence Data; Okadaic Acid; Peptide Mapping; Peritoneal Cavity; Phospholipases A; Phospholipases A2; Phosphorylation; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
An activation-associated ganglioside in rat thymocytes.
Topics: Animals; Calcimycin; Carbohydrate Sequence; Concanavalin A; Gangliosides; Male; Molecular Sequence Data; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thymus Gland | 1993 |
Phorbol ester induces apoptosis in HL-60 promyelocytic leukemia cells but not in HL-60 PET mutant.
Topics: Apoptosis; Calcimycin; DNA Damage; DNA, Neoplasm; Drug Tolerance; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Mutation; Novobiocin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Regulation of apoptosis in thymocytes.
Topics: Animals; Antigen-Presenting Cells; Apoptosis; Calcimycin; CD3 Complex; Cell Differentiation; Cells, Cultured; Cyclosporine; Female; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1993 |
Studies on the metabolism of metallothionein and alkaline phosphatase of adult rat primary hepatocyte cultures: role of fetal calf serum and agonists of the phosphoinositide cascade.
Topics: Alkaline Phosphatase; Angiotensin II; Animals; Arginine Vasopressin; Calcimycin; Cells, Cultured; Culture Media; Dexamethasone; Diglycerides; Liver; Metallothionein; Phosphatidylinositols; Platelet Activating Factor; Rats; Tetradecanoylphorbol Acetate; Zinc | 1993 |
Purification of the 120 kDa component of the human nuclear factor of activated T cells (NF-AT): reconstitution of binding activity to the cis-acting element of the GM-CSF and IL-2 promoter with AP-1.
Topics: Base Sequence; Binding Sites; Calcimycin; Chromatography, Affinity; Chromatography, Ion Exchange; Cytokines; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-2; Molecular Sequence Data; Molecular Weight; NFATC Transcription Factors; Nuclear Proteins; Oligodeoxyribonucleotides; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1993 |
Regulation of interleukin-6 (IL-6) expression: evidence for a tissue-specific role of protein kinase C.
Topics: Alkaloids; Base Sequence; Calcimycin; Carcinoma, Squamous Cell; DNA-Binding Proteins; Gene Expression Regulation; Interleukin-1; Interleukin-6; Laryngeal Neoplasms; Lipopolysaccharides; Molecular Sequence Data; Monocytes; NF-kappa B; Organ Specificity; Polymerase Chain Reaction; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1993 |
The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT.
Topics: Animals; Base Sequence; Calcimycin; Cell Line; DNA; DNA-Binding Proteins; Gene Expression; Genes, Reporter; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lymphocyte Activation; Lymphokines; Mice; Molecular Sequence Data; NFATC Transcription Factors; Nuclear Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 1993 |
Volume-dependent regulation of the respiratory burst of activated human neutrophils.
Topics: Adult; Calcimycin; Humans; Hydrogen Peroxide; Hydroxyl Radical; Immunoglobulin G; In Vitro Techniques; Kinetics; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Oxygen; Photochemistry; Singlet Oxygen; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Cytokine profile of viral and autoimmune chronic active hepatitis.
Topics: Adult; Autoimmune Diseases; Calcimycin; Concanavalin A; Cytokines; Female; Hepatitis B; Hepatitis, Chronic; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-2; Interleukin-4; Interleukin-6; Leukocytes, Mononuclear; Male; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Tumour necrosis factor-alpha enhances cAMP-induced programmed cell death in mouse thymocytes.
Topics: 2-Chloroadenosine; Animals; Apoptosis; Calcimycin; Cell Survival; Cells, Cultured; Cyclic AMP; Dinoprostone; DNA Damage; Humans; Interferon-gamma; Isoproterenol; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred BALB C; Nucleosomes; Recombinant Proteins; T-Lymphocyte Subsets; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Enhancement of A23187-induced arachidonic acid liberation by vasopressin is sensitive to genistein in rabbit platelets.
Topics: Acetophenones; Adenosine Triphosphate; Alkaloids; Animals; Arachidonic Acid; Blood Platelets; Calcimycin; Drug Synergism; Epinephrine; Genistein; Isoflavones; Phospholipases A; Phospholipases A2; Platelet Aggregation; Protein Kinase C; Protein-Tyrosine Kinases; Rabbits; Staurosporine; Tetradecanoylphorbol Acetate; Vasopressins | 1993 |
Tyrosine kinase-dependent suppression of a potassium channel by the G protein-coupled m1 muscarinic acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; Brain; Calcimycin; Calcium; Cell Line; Embryo, Mammalian; Embryo, Nonmammalian; Female; Genistein; GTP-Binding Proteins; Humans; Isoflavones; Kidney; Kinetics; Membrane Potentials; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocardium; Neuroblastoma; Oocytes; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Xenopus | 1993 |
Adhesive interactions of neutrophils and leukotriene synthesis.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Cell Adhesion; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leukotriene B4; Neutrophils; Tetradecanoylphorbol Acetate | 1993 |
Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity.
Topics: Animals; Base Sequence; Calcimycin; Cell Line; Colforsin; Cyclic AMP; DNA-Binding Proteins; Gene Expression Regulation; Insulin; Iodide Peroxidase; Kinetics; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Regulatory Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Transcription Factors; Transcription, Genetic; Transfection | 1993 |
Formation of diacylglycerol, inositol phosphates, arachidonic acid and its metabolites in macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Cyclohexanones; Diglycerides; Fluorides; Inositol Phosphates; Macrophages; Male; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Mobilization of intracellular calcium in cultured vascular smooth muscle cells by uridine triphosphate and the calcium ionophore A23187.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Cattle; Cells, Cultured; Cytidine Triphosphate; GTP-Binding Proteins; Guanosine Triphosphate; Muscle Contraction; Muscle, Smooth, Vascular; Pertussis Toxin; Potassium Channels; Protein Kinase C; Tetradecanoylphorbol Acetate; Uridine Triphosphate; Virulence Factors, Bordetella | 1993 |
Identification of phospholipase D (PLD) activity in mouse peritoneal macrophages.
Topics: Animals; Calcimycin; Cells, Cultured; Chromatography, Thin Layer; Glycerophospholipids; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Phosphatidic Acids; Phospholipase D; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Activin modulates the intracellular signaling system activated by gonadotropin-releasing hormone: dual effect on calcium messenger system and protein kinase-C pathway.
Topics: Activins; Alkaloids; Animals; Calcimycin; Calcium; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Inhibins; Intracellular Membranes; Luteinizing Hormone; Marine Toxins; Oxocins; Protein Kinase C; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
1,25(OH)2D3 increases cytotoxicity and exocytosis in lymphokine-activated killer cells.
Topics: Analysis of Variance; Calcimycin; Calcitriol; Cell Division; Cell Line; Cytotoxicity, Immunologic; Exocytosis; Humans; Killer Cells, Lymphokine-Activated; Tetradecanoylphorbol Acetate | 1993 |
Secretion from rat basophilic RBL-2H3 cells is associated with diphosphorylation of myosin light chains by myosin light chain kinase as well as phosphorylation by protein kinase C.
Topics: Alkaloids; Animals; Antigens; Basophils; Calcimycin; Carbazoles; Cells, Cultured; Egtazic Acid; Indoles; Maleimides; Myosin-Light-Chain Kinase; Myosins; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1994 |
Ni2+ impairs thrombin-induced signal transduction by acting on the agonist and/or receptor in human platelets.
Topics: Alkaloids; Blood Platelets; Calcimycin; Calcium; Cell Membrane; Cytosol; Fura-2; Humans; In Vitro Techniques; Kinetics; Nickel; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Receptors, Thrombin; Signal Transduction; Spectrometry, Fluorescence; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Diradylglycerols stimulate phospholipase A2 and subsequent exocytosis in ram spermatozoa. Evidence that the effect is not mediated via protein kinase C.
Topics: Acrosome; Animals; Arachidonic Acid; Calcimycin; Calcium; Diglycerides; Enzyme Activation; Exocytosis; Glycerides; Male; Phorbol 12,13-Dibutyrate; Phospholipases A; Phospholipases A2; Protein Kinase C; Sheep; Spermatozoa; Tetradecanoylphorbol Acetate | 1994 |
Mechanisms of action for an androgen-mediated autoregulatory process in rat thecal-interstitial cells.
Topics: Androgens; Animals; Calcimycin; Calcium; Cholesterol Side-Chain Cleavage Enzyme; Chorionic Gonadotropin; Female; Homeostasis; Nandrolone; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Steroid 17-alpha-Hydroxylase; Tetradecanoylphorbol Acetate; Theca Cells; Verapamil | 1993 |
Immobilized anti-TCR mAb induces split functions in a CD8+ CTL clone.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; CD8 Antigens; Clone Cells; Cytotoxicity, Immunologic; Immune Tolerance; In Vitro Techniques; Interferon-gamma; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Interleukin-2; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
S-D-lactoylglutathione accumulation in activated human platelets.
Topics: Blood Platelets; Calcimycin; Glutathione; Humans; In Vitro Techniques; Lactoylglutathione Lyase; Platelet Activating Factor; Platelet Activation; Tetradecanoylphorbol Acetate; Thiolester Hydrolases; Thrombin | 1993 |
Activation and desensitization of phospholipase D in intact rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcimycin; Diglycerides; Enzyme Activation; Ethanol; Glycerophospholipids; Liver; Male; Phosphatidic Acids; Phospholipase D; Rats; Rats, Sprague-Dawley; Stearic Acids; Tetradecanoylphorbol Acetate; Time Factors; Vasopressins | 1994 |
A new human cell line for the molecular dissection of the requirement for interleukin-1 in the production of interleukin-2 by immature T cells.
Topics: Bone Marrow Cells; Calcimycin; Cell Line; Dose-Response Relationship, Drug; Humans; Infant; Interleukin-1; Interleukin-2; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1994 |
An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking.
Topics: Amino Acid Sequence; Antigens, Viral; Calcimycin; Calcium; Capsid; Cell Line, Transformed; Cell Transformation, Viral; Cross-Linking Reagents; Herpesvirus 4, Human; Humans; Molecular Sequence Data; Protein Kinase C; Receptors, Antigen, B-Cell; Tetradecanoylphorbol Acetate; Viral Matrix Proteins; Virus Activation; Virus Replication | 1994 |
Effect of costimulants on interleukin-2-like activities from goat peripheral blood mononuclear cells.
Topics: Animals; Calcimycin; Cells, Cultured; Culture Media; Drug Combinations; Female; Goats; Indomethacin; Interleukin-2; Leukocytes, Mononuclear; Male; Neutrophils; Tetradecanoylphorbol Acetate | 1993 |
Regulation of the BZLF1 promoter of Epstein-Barr virus by second messengers in anti-immunoglobulin-treated B cells.
Topics: Antibodies; B-Lymphocytes; Base Sequence; Burkitt Lymphoma; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; DNA-Binding Proteins; Drug Synergism; Enzyme Activation; Gene Expression Regulation, Viral; Herpesvirus 4, Human; Humans; Models, Genetic; Molecular Sequence Data; Promoter Regions, Genetic; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Second Messenger Systems; Tetradecanoylphorbol Acetate; Trans-Activators; Tumor Cells, Cultured; Viral Proteins | 1994 |
Reduced phospholipase A2 activity is not accompanied by reduced arachidonic acid release.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Blotting, Western; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Gene Expression; Genetic Vectors; Kinetics; Mice; Phospholipases A; Phospholipases A2; Platelet-Derived Growth Factor; RNA, Antisense; Tetradecanoylphorbol Acetate; Transfection | 1994 |
Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase.
Topics: Amino Acid Sequence; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Consensus Sequence; Hepatocyte Growth Factor; Humans; Kinetics; Molecular Sequence Data; Peptide Fragments; Phosphates; Phosphopeptides; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-met; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Sequence Homology, Amino Acid; Serine; Stomach Neoplasms; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Inositol phosphate-diacylglycerol signaling pathway in regulation of intraocular pressure.
Topics: Alkaloids; Animals; Aqueous Humor; Calcimycin; Diglycerides; Inositol Phosphates; Intraocular Pressure; Protein Kinase C; Rabbits; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Molecular basis for developmental changes of GM-CSF gene inducibility in embryonal carcinoma cells.
Topics: Animals; Base Sequence; Calcimycin; Carcinoma, Embryonal; Cell Differentiation; DNA Mutational Analysis; DNA-Binding Proteins; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Granulocyte-Macrophage Colony-Stimulating Factor; Mice; Molecular Sequence Data; Protein Binding; Regulatory Sequences, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1994 |
Activation of a voltage-dependent chloride current in human neutrophils by phorbol 12-myristate 13-acetate and formyl-methionyl-leucyl-phenylalanine. The role of protein kinase C.
Topics: Calcimycin; Calcium; Cell Membrane; Chloride Channels; Egtazic Acid; Humans; In Vitro Techniques; Kinetics; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Peptide Fragments; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
Regulation of phospholipase A2 activity in undifferentiated and neutrophil-like HL60 cells. Linkage between impaired responses to agonists and absence of protein kinase C-dependent phosphorylation of cytosolic phospholipase A2.
Topics: Adenosine Triphosphate; Aluminum Compounds; Arachidonic Acid; Blotting, Western; Bucladesine; Calcimycin; Calcium; Cell Differentiation; Cell Line; Cytosol; Electrophoresis, Polyacrylamide Gel; Fluorides; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Leukemia, Promyelocytic, Acute; Neutrophils; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Differential roles for triglyceride and phospholipid pools of arachidonic acid in human lung macrophages.
Topics: Arachidonic Acid; Calcimycin; Eicosanoids; Humans; In Vitro Techniques; Macrophage Activation; Macrophages, Alveolar; Phospholipases; Phospholipids; Tetradecanoylphorbol Acetate; Triglycerides | 1994 |
Involvement of protein kinase C in macrophage activation by poly(I.C).
Topics: Animals; Calcimycin; Complement Factor B; Interferon-beta; Interferon-gamma; Isoenzymes; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Poly I-C; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
Influence of dichloromethylene diphosphonate on reactive oxygen species production by human neutrophils.
Topics: Bone Resorption; Calcimycin; Clodronic Acid; Dose-Response Relationship, Drug; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Xanthine Oxidase; Xanthines | 1993 |
Differential secretion of follicle-stimulating hormone and luteinizing hormone from ovine pituitary cells following activation of protein kinase A, protein kinase C, or increased intracellular calcium.
Topics: Animals; Bucladesine; Calcimycin; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Pituitary Gland; Protein Kinase C; Protein Kinases; Sheep; Tetradecanoylphorbol Acetate | 1994 |
Experimentally induced parthenogenetic activation of human oocytes.
Topics: Calcimycin; Calcium; DNA; Ethanol; Female; Humans; Oocytes; Parthenogenesis; Puromycin; Tetradecanoylphorbol Acetate | 1993 |
Regulation of the polyspermy block in the mouse egg: maturation-dependent differences in cortical granule exocytosis and zona pellucida modifications induced by inositol 1,4,5-trisphosphate and an activator of protein kinase C.
Topics: Animals; Calcimycin; Egg Proteins; Enzyme Activation; Exocytosis; Female; Inositol 1,4,5-Trisphosphate; Male; Membrane Glycoproteins; Mice; Oocytes; Protein Kinase C; Receptors, Cell Surface; Sperm-Ovum Interactions; Tetradecanoylphorbol Acetate; Zona Pellucida; Zona Pellucida Glycoproteins | 1993 |
Protein kinase C activation and calcium mobilization decrease prolactin release from human decidual cells in early pregnancy.
Topics: Calcimycin; Calcium; Cells, Cultured; Decidua; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Female; Humans; Pregnancy; Pregnancy Trimester, First; Prolactin; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
Mucin secretion by T84 cells: stimulation by PKC, Ca2+, and a protein kinase activated by Ca2+ ionophore.
Topics: Adenocarcinoma; Alkaloids; Calcimycin; Calcium; Colonic Neoplasms; Culture Media; Down-Regulation; Egtazic Acid; Humans; Mucins; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Differential signal requirement for upregulation of HLA-class II molecules in human lymphoma B cells.
Topics: Antibodies; Calcimycin; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Histocompatibility Antigens Class II; Humans; Immunoglobulin M; Interleukin-4; Lymphoma, B-Cell; Protein Kinase C; Receptors, Fc; Receptors, IgE; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1993 |
Characterization of the 50 kDa protein phosphorylated in concanavalin A-stimulated mouse T cells.
Topics: Amino Acid Sequence; Animals; Calcimycin; Calcium-Binding Proteins; Chromatography, High Pressure Liquid; Concanavalin A; Electrophoresis, Gel, Two-Dimensional; Female; Lymphocyte Activation; Mice; Microfilament Proteins; Molecular Sequence Data; Molecular Weight; Phosphorylation; Phosphoserine; Phosphothreonine; Sequence Alignment; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1993 |
Molecular mechanisms of decreased interleukin-2 production after thermal injury.
Topics: Animals; Burns; Calcimycin; Interleukin-1; Interleukin-2; Lymphocyte Activation; Male; Mice; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1993 |
Modulation of activin A action and specificity in the rat gonadotrope by protein kinase C.
Topics: Activins; Alkaloids; Animals; Calcimycin; Dimethyl Sulfoxide; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Inhibins; Kinetics; Luteinizing Hormone; Pituitary Gland; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Control of HLA-DR antigen expression by gamma-interferon: separate signal transduction mechanisms in malignant and nonmalignant human thyroid cells.
Topics: Alkaloids; Calcimycin; Carcinoma; Cells, Cultured; Dose-Response Relationship, Drug; Drug Administration Schedule; Goiter; HLA-DR Antigens; Humans; Interferon-gamma; Isoquinolines; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Tumor Cells, Cultured | 1993 |
Calcium-binding myeloid protein (P8,14) is phosphorylated in fMet-Leu-Phe-stimulated neutrophils.
Topics: Calcimycin; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Calmodulin; Cell Adhesion Molecules, Neuronal; Humans; In Vitro Techniques; Leukocyte L1 Antigen Complex; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Precipitin Tests; Tetradecanoylphorbol Acetate; Trifluoperazine | 1993 |
Inhibitors of Ca2+ channels, calmodulin and protein kinases prevent A23187 and other inductions of metallothionein mRNA in EC3 rat hepatoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Chloroadenosine; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Gallic Acid; Isoquinolines; Liver Neoplasms, Experimental; Metallothionein; Norepinephrine; Piperazines; Protein Kinase Inhibitors; Rats; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil | 1993 |
The interleukin-6 (IL-6)/IL-6-receptor system induces human chorionic gonadotropin production by activating tyrosine kinase-dependent signal transduction pathway different from pathways triggered by protein kinase activators including gonadotropin releasi
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Calcimycin; Calmodulin; Chorionic Gonadotropin; Enzyme Activation; Female; Genistein; Gonadotropin-Releasing Hormone; Humans; Interleukin-1; Interleukin-6; Isoflavones; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Receptors, Immunologic; Receptors, Interleukin-6; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Trophoblasts; Tumor Necrosis Factor-alpha | 1993 |
Human mast cells produce IL-8.
Topics: Calcimycin; Cell Line; Chemotaxis, Leukocyte; Gene Expression; Humans; In Vitro Techniques; Interleukin-8; Mast Cells; Molecular Weight; RNA, Messenger; Tetradecanoylphorbol Acetate | 1993 |
Enhancement of pertussis-toxin-sensitive Na(+)-dependent uridine transporter activity in HL-60 granulocytes by N-formylmethionyl-leucyl-phenylalanine.
Topics: Amino Acid Sequence; Biological Transport; Calcimycin; Calcium; Extracellular Space; Granulocytes; Humans; In Vitro Techniques; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Sodium; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uridine; Virulence Factors, Bordetella | 1993 |
cPLA2 is phosphorylated and activated by MAP kinase.
Topics: Amino Acid Sequence; Animals; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; CHO Cells; Cricetinae; Cytosol; Enzyme Activation; Kinetics; Models, Biological; Mutagenesis, Site-Directed; Peptide Mapping; Phospholipases A; Phospholipases A2; Phosphopeptides; Phosphorylation; Protein Kinase C; Protein Kinases; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Serine; Tetradecanoylphorbol Acetate; Transfection | 1993 |
Adenosine inhibits fMLP-stimulated adherence and superoxide anion generation by human neutrophils at an early step in signal transduction.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Calcimycin; Cell Adhesion; Cell Membrane; Complement C5a; GTP-Binding Proteins; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Signal Transduction; Sodium Fluoride; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1993 |
Cross talk of dual-signal transduction systems in the regulation of DNA synthesis by parathyroid hormone in osteoblastic osteosarcoma cells.
Topics: Bucladesine; Calcimycin; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Ionomycin; Osteoblasts; Osteosarcoma; Parathyroid Hormone; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Prostanoid release by Kupffer cells upon hypoxia-reoxygenation: role of pHi and Cai2+.
Topics: Amiloride; Animals; Anti-Infective Agents; Biphenyl Compounds; Calcimycin; Calcium; Carrier Proteins; Cell Survival; Cells, Cultured; Dinoprostone; Hydrogen-Ion Concentration; Hypoxia; Kupffer Cells; Leukotriene B4; Male; NADH, NADPH Oxidoreductases; NADPH Oxidases; Onium Compounds; Oxidation-Reduction; Oxygen; Prostaglandin D2; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1993 |
Regulation of steroidogenesis in NCI-H295 cells: a cellular model of the human fetal adrenal.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Angiotensin II; Aromatase; Base Sequence; Calcimycin; Carcinoma; Cycloheximide; Cytochromes; Enzymes; Gene Expression Regulation, Enzymologic; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Insulin-Like Growth Factor II; Molecular Sequence Data; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Zona Glomerulosa | 1993 |
Cyclic adenosine monophosphate response in primary and subcultured bladder epithelial cells: inhibition by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Alkaloids; Animals; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Cycloheximide; Dogs; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Epithelium; Indomethacin; Models, Biological; Protein Kinase C; Second Messenger Systems; Signal Transduction; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1993 |
Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types.
Topics: Animals; B-Lymphocytes; Calcimycin; Cell Line; CHO Cells; Cricetinae; GTPase-Activating Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Interleukin-3; Kinetics; Mice; Phosphatidylinositol 3-Kinases; Phosphotransferases; Platelet-Derived Growth Factor; Proteins; Proto-Oncogene Proteins p21(ras); ras GTPase-Activating Proteins; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases | 1993 |
Luminol chemiluminescence in rat macrophages and granulocytes: the role of NO, O2-/H2O2, and HOCl.
Topics: Animals; Arginine; Azides; Calcimycin; Catalase; Granulocytes; Hydrogen Peroxide; Hypochlorous Acid; Kupffer Cells; Luminescent Measurements; Luminol; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Nitric Oxide; Rats; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1993 |
Inhibition of macrophage superoxide generation by dehydroepiandrosterone.
Topics: Animals; Calcimycin; Dehydroepiandrosterone; Digitonin; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Macrophages; NADH, NADPH Oxidoreductases; NADPH Oxidases; Rats; Steroids; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Xanthine Oxidase | 1993 |
Involvement of dual signal transduction systems in the stimulation of osteoclast-like cell formation by parathyroid hormone and parathyroid hormone-related peptide.
Topics: Animals; Bucladesine; Calcimycin; Cells, Cultured; Culture Media, Conditioned; Culture Media, Serum-Free; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Ionomycin; Mice; Mice, Inbred Strains; Osteoblasts; Osteoclasts; Osteosarcoma; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Protein Kinase C; Protein Kinases; Proteins; Rats; Second Messenger Systems; Signal Transduction; Teriparatide; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Rapid and sustained phosphorylation of a calmodulin-binding protein (CaM-BP100) in NGF-treated PC12 cells.
Topics: Animals; Bradykinin; Brain; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Calmodulin-Binding Proteins; Carbachol; Cattle; Colforsin; Cyclic AMP; Cytosol; Epidermal Growth Factor; Fibroblast Growth Factor 2; Ionomycin; Kinetics; Nerve Growth Factors; PC12 Cells; Phosphorylation; Protein Kinases; Tetradecanoylphorbol Acetate; Thionucleotides | 1993 |
Modulation of beta-amyloid precursor protein secretion in differentiated and nondifferentiated cells.
Topics: Amyloid beta-Protein Precursor; Animals; Bucladesine; Calcimycin; Carcinogens; Cell Differentiation; Cell Line; Culture Media; PC12 Cells; Phorbol 12,13-Dibutyrate; Phorbol Esters; Tetradecanoylphorbol Acetate | 1993 |
Interactions between human immunodeficiency virus infection and hormonal pathways: enhancement of calcium-induced but reduction of glucocorticoid-induced cell death.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Apoptosis; Bucladesine; Calcimycin; Calcium; Cell Death; Dexamethasone; Glucocorticoids; HIV-1; Humans; Leukemia; Protein Kinase C; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Inhibition of human mononuclear cell proliferation, interleukin synthesis, mRNA for IL-2, IL-6, and leukotriene B4 synthesis by a lipoxygenase inhibitor.
Topics: Acetamides; Calcimycin; Cell Division; Cells, Cultured; Gene Expression; Humans; Interleukin-2; Interleukin-6; Kinetics; Leukocytes, Mononuclear; Leukotriene B4; Lipoxygenase Inhibitors; Phenyl Ethers; Phytohemagglutinins; Receptors, Interleukin-2; RNA, Messenger; Tetradecanoylphorbol Acetate | 1993 |
Antirheumatic gold compounds and penicillamine enhance protein kinase C-mediated activation of the arachidonate-mobilizing phospholipase A2 in mouse macrophages.
Topics: Animals; Arachidonic Acid; Auranofin; Aurothioglucose; Calcimycin; Eicosanoids; Enzyme Activation; Gold Sodium Thiomalate; Kinetics; Macrophages, Peritoneal; Mice; Molecular Weight; Penicillamine; Phospholipases A; Phospholipases A2; Phosphoproteins; Protein Kinases; Tetradecanoylphorbol Acetate | 1993 |
Elevated levels of neutrophil 4-hydroxynonenal in canine neuronal ceroid-lipofuscinosis and human immortalized lymphocytes of NCL patients.
Topics: Aldehydes; Animals; Calcimycin; Cell Line, Transformed; Dogs; Herpesvirus 4, Human; Humans; Lymphocytes; Neuronal Ceroid-Lipofuscinoses; Neutrophils; Tetradecanoylphorbol Acetate | 1993 |
Protein kinase C inhibits the Ca(2+)-activated K+ channel of cultured porcine coronary artery smooth muscle cells.
Topics: Adenosine Triphosphate; Animals; Brain; Calcimycin; Calcium; Cells, Cultured; Coronary Vessels; Diglycerides; Ion Channel Gating; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Channels; Probability; Protein Kinase C; Rats; Swine; Tetradecanoylphorbol Acetate | 1993 |
Regulation of proteins in the cholesterol side-chain cleavage system in JEG-3 and Y-1 cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex Neoplasms; Adrenodoxin; Animals; Calcimycin; Cholesterol Side-Chain Cleavage Enzyme; Choriocarcinoma; Cloning, Molecular; Escherichia coli; Ferredoxin-NADP Reductase; Genetic Vectors; Humans; Kinetics; Mice; Mitochondria; Plasmids; Pregnenolone; Protein Kinase C; Protein Kinases; Recombinant Proteins; Restriction Mapping; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Bradykinin and vasopressin activate phospholipase D in rat Leydig cells by a protein kinase C-dependent mechanism.
Topics: Animals; Arginine Vasopressin; Bradykinin; Calcimycin; Calcium; Cells, Cultured; Choline; Dose-Response Relationship, Drug; Enzyme Activation; Ethanol; Leydig Cells; Male; Phospholipase D; Protein Kinase C; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1993 |
Characterization of neutral endopeptidase in vascular smooth muscle cells of rabbit renal cortex.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Calcimycin; Cattle; Cell Membrane; Kidney Cortex; Muscle, Smooth, Vascular; Neprilysin; Rabbits; Renal Circulation; RNA, Messenger; Tetradecanoylphorbol Acetate; Tissue Distribution | 1993 |
Role of protein kinase C in bradykinin-induced prostaglandin formation in osteoblasts.
Topics: Alkaloids; Animals; Bradykinin; Calcimycin; Cell Membrane; Cells, Cultured; Dinoprostone; Enzyme Activation; Hydrocortisone; Indomethacin; Mice; Osteoblasts; Phorbol 12,13-Dibutyrate; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Expression of PILOT, a putative transcription factor, requires two signals and is cyclosporin A sensitive in T cells.
Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Calcimycin; Cell Line; Cycloheximide; Cyclosporine; DNA; Drug Synergism; Early Growth Response Protein 3; Escherichia coli; Gene Expression Regulation; Humans; Molecular Sequence Data; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transcription, Genetic; Zinc Fingers | 1993 |
Cell adherence to fibronectin and the aggregation of the high affinity immunoglobulin E receptor synergistically regulate tyrosine phosphorylation of 105-115-kDa proteins.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Calcimycin; Fibronectins; Molecular Sequence Data; Molecular Weight; Phosphorylation; Precipitin Tests; Proteins; Rats; Receptor Aggregation; Receptors, IgE; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1993 |
Novel antibodies specific for proteolyzed forms of protein kinase C: production of anti-peptide antibodies available for in situ analysis of intracellular limited proteolysis.
Topics: Amino Acid Sequence; Animals; Antibodies; Antibody Formation; Calcimycin; Calpain; Cell Line; Immunoblotting; Immunohistochemistry; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Fragments; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1993 |
Protein kinase C, a pivotal regulator of hamster egg activation, functions after elevation of intracellular free calcium.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Cricetinae; Diglycerides; Egtazic Acid; Enzyme Activation; Female; Kinetics; Mesocricetus; Ovum; Phorbol Esters; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Transcript levels of thymosin beta 4, an actin-sequestering peptide, in cell proliferation.
Topics: Actins; Animals; Calcimycin; Cell Division; Concanavalin A; Gene Expression; Humans; Leukemia; Liver; Liver Regeneration; Lymphocytes; Peptides; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymosin; Thymus Gland; Time Factors | 1993 |
Regulation of glycoinositol phospholipid anchor assembly in human lymphocytes. Absent mannolipid synthesis in affected T and natural killer cell lines from paroxysmal nocturnal hemoglobinuria patients.
Topics: Animals; Calcimycin; Carbohydrate Sequence; Cell Line; Glycosylphosphatidylinositols; Hemoglobinuria, Paroxysmal; Humans; Killer Cells, Natural; Lymphocyte Activation; Mice; Molecular Sequence Data; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1993 |
Productive infection of continuous lines of channel catfish leukocytes by channel catfish virus.
Topics: Animals; B-Lymphocytes; Calcimycin; Cell Line; Herpesviridae; Ictaluridae; Leukocytes; Macrophages; Molecular Weight; T-Lymphocytes; Tetradecanoylphorbol Acetate; Viral Proteins; Virus Replication | 1993 |
Tyrosine phosphorylation of pp125FAK by the aggregation of high affinity immunoglobulin E receptors requires cell adherence.
Topics: Animals; Calcimycin; Cell Adhesion; Cell Adhesion Molecules; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Immunoblotting; Kinetics; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor Aggregation; Receptors, IgE; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1993 |
Contribution of platelet microparticle formation and granule secretion to the transmembrane migration of phosphatidylserine.
Topics: Alkaloids; Biological Transport; Blood Platelets; Calcimycin; Calcium; Carrier Proteins; Complement Membrane Attack Complex; Cytoplasmic Granules; Exocytosis; Flow Cytometry; Fluorescence; Humans; Kinetics; Membrane Fusion; Membrane Proteins; Phosphatidylserines; Phospholipid Transfer Proteins; Phospholipids; Platelet Activation; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Over-expression of protein kinase C-alpha enhances platelet-derived growth factor- and phorbol ester- but not calcium ionophore-induced formation of prostaglandins in NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Calcimycin; Calcium; Mice; Platelet-Derived Growth Factor; Prostaglandins; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
Progesterone modulation of gonadotropin secretion by dispersed rat pituitary cells in culture. IV. Follicle-stimulating hormone synthesis and release.
Topics: Animals; Calcimycin; Cells, Cultured; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Kinetics; Luteinizing Hormone; Mifepristone; Pituitary Gland, Anterior; Progesterone; Promegestone; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1993 |
Tumor necrosis factor-alpha potentiates phospholipase A2-stimulated release and metabolism of arachidonic acid in cultured intestinal epithelial cells (INT 407).
Topics: Arachidonic Acid; Calcimycin; Cell Line; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Epithelium; Humans; Intestinal Mucosa; Lipid Metabolism; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Type C Phospholipases | 1993 |
Reconstitution of the functional granulocyte macrophage colony stimulating factor promoter: evidence for distinct activation mechanisms that mediate the response to phorbol ester/calcium and human T cell leukemia virus type I Tax signals.
Topics: Base Sequence; Calcimycin; Cell Line; DNA; Gene Expression Regulation; Genes, pX; Granulocyte-Macrophage Colony-Stimulating Factor; Human T-lymphotropic virus 1; Humans; Interleukin-3; Interleukin-5; Molecular Sequence Data; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate | 1993 |
Agents that activate protein kinase C rescue sheep ileal Peyer's patch B cells from apoptosis.
Topics: Alkaloids; Animals; Antigens, Surface; Apoptosis; B-Lymphocytes; Calcimycin; Calcium; Cell Size; DNA Damage; Enzyme Activation; Female; Ileum; Male; Peyer's Patches; Protein Kinase C; Sheep; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Calcium dependent activation of the NF-AT transcription factor by p59fyn.
Topics: Calcimycin; Calcium; Chloramphenicol O-Acetyltransferase; Cyclosporine; DNA-Binding Proteins; Egtazic Acid; Humans; NFATC Transcription Factors; Nuclear Proteins; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Recombinant Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured | 1993 |
Differential regulation of phospholipase D and phospholipase C by protein kinase C-beta and -delta in liver macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Carcinogens; Enzyme Activation; Fluorides; Inositol Phosphates; Ionophores; Isoenzymes; Liver; Macrophages; Male; Phospholipase D; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Type C Phospholipases; Zymosan | 1995 |
Specific decrease of Th1-like activity in mice with plasma cell tumors.
Topics: Animals; Calcimycin; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Concanavalin A; Cytokines; Female; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Plasmacytoma; Spleen; Tetradecanoylphorbol Acetate; Th1 Cells; Tumor Cells, Cultured | 1995 |
Nitration of tyrosyl-residues from extra- and intracellular proteins in human whole blood.
Topics: Blood Proteins; Calcimycin; Humans; Ionophores; Kinetics; Neutrophils; Nitrates; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine | 1995 |
Chronic oral administration of synthetic trypsin inhibitor camostate reduces amylase release from isolated rat pancreatic acini.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Administration, Oral; Amylases; Animals; Calcimycin; Carbachol; Cholecystokinin; Esters; Gabexate; Guanidines; In Vitro Techniques; Male; Pancreas; Rats; Rats, Wistar; Secretin; Sincalide; Tetradecanoylphorbol Acetate; Trypsin Inhibitors | 1995 |
Phorbol ester-induced suppression of leukotriene C4 synthase activity in human granulocytes.
Topics: Calcimycin; Catalase; Glutathione Transferase; Granulocytes; Humans; Kinetics; Leukotriene A4; Leukotriene B4; Leukotriene C4; Protein Kinase C; Tetradecanoylphorbol Acetate | 1995 |
Seasonal variations of interleukin-4 and interferon-gamma release by peripheral blood mononuclear cells from atopic subjects stimulated by polyclonal activators.
Topics: Adolescent; Adult; Aged; Calcimycin; Child; Female; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Interferon-gamma; Interleukin-4; Leukocytes, Mononuclear; Male; Middle Aged; Pollen; Seasons; Tetradecanoylphorbol Acetate; Trees | 1995 |
Differential involvement of protein kinase C in activating cytosolic phospholipase A2 in alveolar macrophages and monocyte differentiated U937 cells.
Topics: Animals; Arachidonic Acid; Calcimycin; Cell Differentiation; Cell Line; Cytosol; Enzyme Activation; Guinea Pigs; Macrophages, Alveolar; Monocytes; Phospholipases A; Phospholipases A2; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1995 |
Comparison of apoptosis signaling through T cell receptor, fas, and calcium ionophore.
Topics: Antibodies, Monoclonal; Apoptosis; Calcimycin; Calcium; CD3 Complex; Cytokines; fas Receptor; Humans; Ionophores; Leukemia, T-Cell; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Receptors, Antigen, T-Cell; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1996 |
Redistribution of fodrin in an in vitro wound healing model of the corneal epithelium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Carrier Proteins; Cattle; Cell Membrane; Cells, Cultured; Cornea; Cytoplasm; Egtazic Acid; Epithelial Cells; Epithelium; Isoquinolines; Membrane Proteins; Microfilament Proteins; Microscopy, Fluorescence; Naphthalenes; Piperazines; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Wound Healing | 1995 |
Interleukin-4 gene expression in activated human T lymphocytes is regulated by the cyclic adenosine monophosphate-dependent signaling pathway.
Topics: Antibodies, Monoclonal; Bucladesine; Calcimycin; CD28 Antigens; Concanavalin A; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Gene Expression Regulation; Humans; Interleukin-4; Interleukins; Lymphocyte Activation; Muromonab-CD3; Recombinant Proteins; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Calpain secreted by activated human lymphoid cells degrades myelin.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Calcium; Calcium-Binding Proteins; Calpain; Chelating Agents; Culture Media, Conditioned; Demyelinating Diseases; Egtazic Acid; Humans; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, Large B-Cell, Diffuse; Monocytes; Myelin Basic Protein; Myelin Sheath; Neoplasm Proteins; Protease Inhibitors; Rabbits; Rats; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Stress causes induction of MAP kinase-specific phosphatase and rapid repression of MAP kinase activity in Drosophila.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Drosophila; Enzyme Induction; Heat-Shock Response; Ionophores; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 1995 |
Protein kinase C regulates cytokine-induced tissue factor transcription and procoagulant activity in human endothelial cells.
Topics: Blood Coagulation; Calcimycin; Cell Adhesion; Cytokines; Endothelium, Vascular; Epoprostenol; Ethers, Cyclic; Humans; Interleukin-1; Naphthalenes; Neutrophils; Okadaic Acid; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Thromboplastin; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1996 |
A chemiluminescence method to analyze phosphatidylcholine-phospholipase activity in plasma membrane preparations and in intact cells.
Topics: Animals; Blood Donors; Calcimycin; Cell Membrane; Enzyme Activation; Humans; Hydrolysis; Leukocytes; Linear Models; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylcholines; Phospholipase D; Rats; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1995 |
Ceramide inhibits IgE-mediated activation of phospholipase D, but not of phospholipase C, in rat basophilic leukemia (RBL-2H3) cells.
Topics: Animals; Antigens; Biological Transport; Calcimycin; Calcium; Enzyme Activation; Enzyme Induction; Extracellular Space; Hydrolysis; Immunoglobulin E; Leukemia, Basophilic, Acute; Phosphatidylinositols; Phospholipase D; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1996 |
Short-term and long-term-effects of phorbol 12-myristate 13-acetate and different inhibitors on the ability of bone marrow cells to form colonies in vitro.
Topics: Animals; Arachidonic Acid; Bone Marrow; Bone Marrow Cells; Calcimycin; Enzyme Inhibitors; Growth Inhibitors; Hematopoietic Stem Cells; Ionophores; Lysophosphatidylcholines; Mice; Mice, Inbred CBA; Phospholipases A; Phospholipases A2; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Inhibition of collagen-induced platelet activation by arachidonyl trifluoromethyl ketone.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Collagen; Enzyme Inhibitors; Humans; Phospholipases A; Phospholipases A2; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1995 |
Characterisation of cytosolic phospholipase A2 as mediator of the enhanced arachidonic acid release from dimethyl sulphoxide differentiated U937 cells.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Differentiation; Cell Membrane; Cytosol; Dimethyl Sulfoxide; Enzyme Activation; Heparin; Humans; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Autocrine regulation of membrane transforming growth factor-alpha cleavage.
Topics: Animals; Antibodies; Autoradiography; Calcimycin; Carcinoma, Squamous Cell; Cell Membrane; CHO Cells; Cricetinae; Cysteine; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Protein Precursors; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1996 |
Reactivity of purified complement component 3b with bovine neutrophils and modulation of complement receptor 1.
Topics: Animals; Anti-Inflammatory Agents; Blood Cells; Calcimycin; Carcinogens; Cattle; Cell Separation; Complement C3b; Dose-Response Relationship, Drug; Female; Flow Cytometry; Hydrocortisone; Immune System; Mammary Glands, Animal; Milk; Neutrophils; Receptors, Complement; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 1996 |
Role of cytokines, tyrosine kinase, and protein kinase C on production of superoxide and induction of scavenging enzymes in human leukocytes.
Topics: Adult; Bleomycin; Calcimycin; Catalase; Cytokines; Enzyme Induction; Female; Glutathione Peroxidase; Humans; Interferon-gamma; Interleukin-1; Lymphocytes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; Respiratory Burst; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Differential effects of phorbol ester on apoptosis in HL-60 promyelocytic leukemia cells.
Topics: Apoptosis; Calcimycin; Calcium; Down-Regulation; Enzyme Inhibitors; HL-60 Cells; Homeostasis; Humans; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
The role of oxygen in thymocyte apoptosis.
Topics: Acetylcysteine; Anaerobiosis; Animals; Apoptosis; Calcimycin; Cell Death; DNA-Binding Proteins; Enterotoxins; Female; Gene Expression Regulation; Male; Mercaptoethanol; Mice; Mice, Inbred BALB C; Nuclear Receptor Subfamily 4, Group A, Member 1; Organ Culture Techniques; Oxygen; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Staphylococcus aureus; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland; Transcription Factors | 1996 |
Costimulation of cytokine gene expression in T cells by the human T leukemia/lymphotropic virus type 1 trans activator Tax.
Topics: Base Sequence; Calcimycin; CD28 Antigens; Cell Line; Cytokines; Gene Expression Regulation; Gene Products, tax; Granulocyte-Macrophage Colony-Stimulating Factor; Human T-lymphotropic virus 1; Humans; Molecular Sequence Data; NF-kappa B; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
A novel interferon regulatory factor family transcription factor, ICSAT/Pip/LSIRF, that negatively regulates the activity of interferon-regulated genes.
Topics: Amino Acid Sequence; Animals; Base Sequence; Calcimycin; Carrier Proteins; Consensus Sequence; DNA-Binding Proteins; DNA, Complementary; Gene Expression Regulation; Genes, pX; Humans; Interferon Regulatory Factors; Interferons; Leukemia, T-Cell; Lymphocyte Activation; Molecular Sequence Data; Repressor Proteins; Sequence Homology, Amino Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 1996 |
Formyl-methionyl-leucyl-phenylalanine and a calcium ionophore A23187 reverse the inhibition of phorbol myristate acetate-induced oxidative burst by linoleic and oleic acid anilides.
Topics: Anilides; Calcimycin; Calcium; Carcinogens; Drug Synergism; Humans; Ionophores; Linoleic Acids; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oleic Acids; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate | 1996 |
Regulation of expression of the steroidogenic acute regulatory (StAR) protein by ACTH in bovine adrenal fasciculata cells.
Topics: Adrenocorticotropic Hormone; Animals; Bucladesine; Calcimycin; Cattle; Cells, Cultured; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Hydrocortisone; Immunohistochemistry; Isoquinolines; Kinetics; Naphthalenes; Phosphoproteins; Quinazolines; Sulfonamides; Tetradecanoylphorbol Acetate; Zona Fasciculata | 1996 |
Phospholipase D-derived products in the regulation of 12-O-tetradecanoylphorbol-13-acetate-stimulated prostaglandin synthesis in madin-darby canine kidney cells.
Topics: Animals; Calcimycin; Cell Line; Diglycerides; Dinoprostone; Dogs; Enzyme Activation; Enzyme Induction; Ethanol; Glycerophospholipids; Kidney; Kinetics; Phosphatidic Acids; Phospholipase D; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Kinase C; Tetradecanoylphorbol Acetate | 1996 |
Structural requirements for the ectodomain cleavage of human cell surface macrophage colony-stimulating factor.
Topics: 3T3 Cells; Allosteric Regulation; Amino Acid Sequence; Animals; Brefeldin A; Calcimycin; Cell Membrane; Chloroquine; Cyclopentanes; DNA, Complementary; Humans; Macrophage Colony-Stimulating Factor; Methionine; Mice; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Polymerase Chain Reaction; Protein Conformation; Protein Synthesis Inhibitors; Recombinant Proteins; Sequence Deletion; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Heparin inhibits mitogen-activated protein kinase-dependent and -independent c-fos induction in mesangial cells.
Topics: Amino Acid Sequence; Animals; Blood; Blotting, Northern; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Culture Media; Enzyme Activation; Genes, fos; Glomerular Mesangium; Heparin; Ionomycin; Kinetics; Male; Models, Biological; Molecular Sequence Data; Oligopeptides; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-raf; ras Proteins; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate; Transcription, Genetic; Verapamil | 1996 |
Mechanism of bile salt-induced mucin secretion by cultured dog gallbladder epithelial cells.
Topics: Acetylglucosamine; Animals; Bile Acids and Salts; Calcimycin; Cells, Cultured; Cyclic AMP; Dinoprostone; Dogs; Edetic Acid; Enzyme Activation; Epithelium; Gallbladder; Ionomycin; Kinetics; Mucins; Phorbol 12,13-Dibutyrate; Protein Kinase C; Second Messenger Systems; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetradecanoylphorbol Acetate; Tritium | 1996 |
Tyrosine kinase is involved in angiotensin II-stimulated phospholipase D activation in aortic smooth muscle cells: function of Ca2+ influx.
Topics: Alkaloids; Angiotensin II; Animals; Aorta; Biological Transport; Calcimycin; Calcium; Cells, Cultured; Choline; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Genistein; Inositol Phosphates; Ionophores; Isoflavones; Membrane Lipids; Muscle Proteins; Muscle, Smooth, Vascular; Phosphatidylcholines; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipase D; Phosphoric Diester Hydrolases; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human monocytes and lymphocytes.
Topics: Alcohol Oxidoreductases; Calcimycin; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; Lymphocytes; Monocytes; Neutrophils; Tetradecanoylphorbol Acetate | 1996 |
Effect of staphylococcal enterotoxin B-induced anergy on cytokine gene expression: anergy-sensitive and resistant mRNA expression.
Topics: Animals; Base Sequence; Calcimycin; CD3 Complex; Clonal Anergy; Cytokines; Enterotoxins; Gene Expression Regulation; In Vitro Techniques; Ionophores; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Receptors, Antigen, T-Cell; RNA, Messenger; Staphylococcus aureus; Superantigens; Tetradecanoylphorbol Acetate | 1996 |
Stimulation of arachidonic acid mobilization by adherence of resident peritoneal macrophages to plastic substrate.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Cattle; Cell Adhesion; Cells, Cultured; Enzyme Inhibitors; Fetal Blood; Kinetics; Macrophages, Peritoneal; Male; Mice; Phospholipases A; Phospholipases A2; Plastics; Tetradecanoylphorbol Acetate | 1996 |
Rat eosinophils: isolation and characterization of superoxide production.
Topics: Animals; Calcimycin; Cell Separation; Cytochalasin B; Eosinophils; Humans; In Vitro Techniques; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Regulation of membrane-type matrix metalloproteinase-1 expression by growth factors and phorbol 12-myristate 13-acetate.
Topics: Base Sequence; Calcimycin; Cell Line; Collagenases; Concanavalin A; Cycloheximide; Cytokines; Dexamethasone; DNA Primers; Enzyme Activation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Fibroblasts; Fibrosarcoma; Gelatinases; Gene Expression Regulation, Enzymologic; Growth Substances; Humans; Immunoblotting; Interleukin-1; Lung; Matrix Metalloproteinase 1; Molecular Sequence Data; Polymerase Chain Reaction; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Inhibition of ADP-induced platelet activation by 7-chloro-4-nitrobenz-2-oxa-1,3-diazole: covalent modification of aggregin, a putative ADP receptor.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Chloro-7-nitrobenzofurazan; Adenosine; Adenosine Diphosphate; Blood Platelets; Calcimycin; Calcium; Cell Aggregation; Cell Size; Collagen; Cyclic AMP; Fibrinogen; Humans; Platelet Activation; Platelet Membrane Glycoproteins; Prostaglandin Endoperoxides, Synthetic; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Time Factors | 1996 |
Synergistic cooperation between thapsigargin and phorbol ester for induction of nitric oxide synthesis in murine peritoneal macrophages.
Topics: Animals; Calcimycin; Calcium; Calcium-Transporting ATPases; Chelating Agents; Cytotoxicity, Immunologic; Drug Synergism; Egtazic Acid; Humans; Hydroquinones; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Nitric Oxide; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1996 |
Inhibition of neutrophil-superoxide generation by alpha-tocopherol and coenzyme Q.
Topics: Animals; Antioxidants; Calcimycin; Electron Spin Resonance Spectroscopy; Guinea Pigs; Hydroxyl Radical; In Vitro Techniques; Kinetics; Neutrophils; Peritoneal Cavity; Protein Kinase C; Rats; Superoxides; Tetradecanoylphorbol Acetate; Ubiquinone; Vitamin E; Zymosan | 1996 |
Gelatinase A secretion and its control in peritubular and Sertoli cell cultures: effects of hormones, second messengers and inducers of cytokine production.
Topics: Adenosine Monophosphate; Animals; Calcimycin; Cells, Cultured; Concanavalin A; Cytokines; Follicle Stimulating Hormone; Gelatinases; Interleukin-1; Lipopolysaccharides; Male; Matrix Metalloproteinase 2; Metalloendopeptidases; Rats; Rats, Wistar; Second Messenger Systems; Seminiferous Tubules; Sertoli Cells; Testosterone; Tetradecanoylphorbol Acetate | 1996 |
Contact-induced modulation of neutrophil elastase secretion and phagocytic activity by platelets.
Topics: Blood Platelets; Calcimycin; Humans; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Platelet Activation; Platelet Adhesiveness; Tetradecanoylphorbol Acetate | 1996 |
Oxatomide and derivatives as inhibitors of mediator release from a mast cell model. Structure-activity relationships.
Topics: Animals; Anti-Allergic Agents; Arachidonic Acid; beta-N-Acetylhexosaminidases; Calcimycin; Cells, Cultured; Exocytosis; Histamine H1 Antagonists; Histamine Release; Ionophores; L-Lactate Dehydrogenase; Mast Cells; Piperazines; Rats; Signal Transduction; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1996 |
Cultured retinal capillary pericytes die by apoptosis after an abrupt fluctuation from high to low glucose levels: a comparative study with retinal capillary endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Bucladesine; Calcimycin; Capillaries; Cattle; Cell Survival; Cells, Cultured; Coculture Techniques; DNA; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Isoquinolines; Kinetics; Microscopy, Electron; Muscle, Smooth, Vascular; Niacinamide; Piperazines; Retinal Vessels; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
The functional consequences of partial calcineurin inhibition in human peripheral blood mononuclear leucocytes.
Topics: Blotting, Northern; Calcimycin; Calcineurin; Calmodulin-Binding Proteins; Cyclosporine; Humans; Interferon-gamma; Ionomycin; Leukocytes; Muromonab-CD3; Phosphoprotein Phosphatases; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Rapid stimulation of EAAC1-mediated Na+-dependent L-glutamate transport activity in C6 glioma cells by phorbol ester.
Topics: Adenylyl Cyclases; Amiloride; Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Calcimycin; Carrier Proteins; Colforsin; Enzyme Inhibitors; Ethers, Cyclic; Excitatory Amino Acid Transporter 3; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamates; Glycine; Kinetics; Okadaic Acid; Phosphoric Monoester Hydrolases; Protein Kinase C; Rats; Sodium; Sodium-Potassium-Exchanging ATPase; Symporters; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Endothelin-1 increases arachidonic acid release in C6 glioma cells through a potassium-modulated influx of calcium.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Endothelins; Enzyme Activation; Glioma; Ion Channel Gating; Ionophores; Phospholipases A; Phospholipases A2; Potassium; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Valinomycin | 1996 |
Proliferation-dependent changes in arachidonic acid mobilization from phospholipids of 3T6 fibroblasts.
Topics: Animals; Arachidonic Acid; Bradykinin; Calcimycin; Cell Division; Cell Line; Culture Media; Dinoprostone; Enzyme Inhibitors; Fibroblasts; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phospholipids; Phosphoric Monoester Hydrolases; Tetradecanoylphorbol Acetate | 1996 |
Modification of cultured Madin-Darby canine kidney cells with dietary unsaturated fatty acids and regulation of arachidonate cascade reaction.
Topics: Animals; Arachidonic Acid; Blotting, Western; Calcimycin; Cell Division; Cell Line; Cell Survival; Culture Media; Dinoprostone; Dogs; Enzyme-Linked Immunosorbent Assay; Fatty Acids; Fatty Acids, Unsaturated; Ionophores; Kidney; Phospholipids; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate | 1996 |
Effect of degree of unsaturation in dietary fatty acids on arachidonic acid mobilization by peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Unsaturated; Fish Oils; Macrophage Activation; Macrophages, Peritoneal; Male; Opsonin Proteins; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Triglycerides; Zymosan | 1996 |
Effect of calcitonin gene-related peptide and vasoactive intestinal peptide on murine CD4 and CD8 T cell proliferation.
Topics: Animals; Calcimycin; Calcitonin Gene-Related Peptide; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclic AMP; Drug Synergism; Female; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate; Vasoactive Intestinal Peptide | 1996 |
Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha.
Topics: Alkaloids; Base Sequence; Calcimycin; Cell Hypoxia; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; I-kappa B Proteins; Ionophores; Isoflavones; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Protein Kinase C; Protein Tyrosine Phosphatases; src-Family Kinases; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Dephosphorylation of cofilin in polymorphonuclear leukocytes derived from peripheral blood.
Topics: Actin Depolymerizing Factors; Androstadienes; Animals; Calcimycin; Calcium; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Ethers, Cyclic; Humans; Ionophores; Marine Toxins; Microfilament Proteins; N-Formylmethionine Leucyl-Phenylalanine; Nerve Tissue Proteins; Neutrophil Activation; Neutrophils; Okadaic Acid; Oxazoles; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Swine; Tetradecanoylphorbol Acetate; Wortmannin | 1996 |
Stimulation of granulocyte-macrophage colony-stimulating factor (GM-CSF) production and its role as an autocrine inducer of CD14 upregulation in human myeloid leukemia cells.
Topics: Calcimycin; Cell Differentiation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-1; Ionophores; Leukemia, Myeloid; Lipopolysaccharide Receptors; Recombinant Proteins; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Up-Regulation | 1996 |
Specific T cell unresponsiveness in human filariasis: diversity in underlying mechanisms.
Topics: Animals; Antigens, CD; Antigens, Helminth; Brugia malayi; Calcimycin; Cells, Cultured; Cytokines; Elephantiasis, Filarial; Filariasis; Humans; Indomethacin; Leukocytes, Mononuclear; Microfilariae; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1995 |
Regulation of tight junction resistance in T84 monolayers by elevation in intracellular Ca2+: a protein kinase C effect.
Topics: Arachidonic Acid; Calcimycin; Calcium; Cell Membrane Permeability; Chelating Agents; Egtazic Acid; Humans; Ionophores; Mannitol; Phospholipases; Protein Kinase C; Quinacrine; Tetradecanoylphorbol Acetate; Tight Junctions; Tumor Cells, Cultured | 1996 |
Formation of a 5-oxo metabolite of 5,8,11,14,17-eicosapentaenoic acid and its effects on human neutrophils and eosinophils.
Topics: Alcohol Oxidoreductases; Calcimycin; Calcium; Chemotaxis, Leukocyte; Cytosol; Eicosapentaenoic Acid; Eosinophils; Humans; Neutrophils; Substrate Specificity; Tetradecanoylphorbol Acetate | 1995 |
Dephosphorylation of cofilin in parotid acinar cells.
Topics: Actin Depolymerizing Factors; Amylases; Animals; Calcimycin; Calcium; Carbachol; Cyclic AMP; Cyclosporine; Enzyme Inhibitors; Exocytosis; Ionophores; Isoproterenol; Marine Toxins; Microfilament Proteins; Nerve Tissue Proteins; Oxazoles; Parotid Gland; Phosphoprotein Phosphatases; Phosphorylation; Rats; Tacrolimus; Tetradecanoylphorbol Acetate | 1996 |
[The involvement of protein kinase C isozymes in activation of phospholipase D and secretion of serotonin in rat basophilic leukemia cells].
Topics: Animals; Calcimycin; Calcium; Enzyme Activation; Ionophores; Isoenzymes; Leukemia, Basophilic, Acute; Phospholipase D; Protein Kinase C; Rats; Serotonin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Brefeldin A inhibits antigen- or calcium ionophore-mediated but not PMA-induced phospholipase D activation in rat basophilic leukemia (RBL-2H3) cells.
Topics: Animals; Antigens; Brefeldin A; Calcimycin; Cyclopentanes; Enzyme Activation; Leukemia, Mast-Cell; Phospholipase D; Rats; Serotonin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Binding of the inward rectifier K+ channel Kir 2.3 to PSD-95 is regulated by protein kinase A phosphorylation.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Calcimycin; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Humans; Kidney; Mammals; Molecular Sequence Data; Nerve Tissue Proteins; Peptide Fragments; Phosphorylation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Phosphorylation of myeloid-related proteins MRP-14 and MRP-8 during human neutrophil activation.
Topics: Antigens, Differentiation; Arachidonic Acid; Calcimycin; Calcium; Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Cell Membrane; Cytochalasin B; Cytoplasm; Electrophoresis, Gel, Two-Dimensional; Humans; Immunoblotting; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Phosphorylation; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Phorbol ester, but not endotoxin, desensitizes mannan-induced glycogenolysis in the perfused rat liver.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aprotinin; Calcimycin; Colforsin; Enzyme Inhibitors; Escherichia coli; Leupeptins; Lipopolysaccharides; Liver; Liver Glycogen; Male; Mannans; Norepinephrine; Perfusion; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Dexamethasone represses phorbol ester-, forskolin-, and calcium-stimulated expression of a preproenkephalin A promoter-chloramphenicol acetyltransferase gene via a receptor-mediated mechanism.
Topics: Calcimycin; Cell Line; Chloramphenicol O-Acetyltransferase; Colforsin; Depression, Chemical; Dexamethasone; Enkephalins; Gene Expression Regulation, Enzymologic; Genes, Reporter; Glucocorticoids; Humans; Ionophores; Promoter Regions, Genetic; Protein Precursors; Receptors, Glucocorticoid; Tetradecanoylphorbol Acetate | 1996 |
Lung cancer cell lines inhibit leukotriene B4 production by human polymorphonuclear leukocytes at the level of phospholipase A2.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonic Acid; Calcimycin; Calcium; Coculture Techniques; Cyclooxygenase Inhibitors; Dinoprostone; Erythrocytes; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Ionophores; Leukotriene B4; Lipoxygenase; Lung Neoplasms; Neutrophils; Phospholipases A; Phospholipases A2; Subcellular Fractions; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Regulation of taurine transport in rat astrocytes by protein kinase C: role of calcium and calmodulin.
Topics: Animals; Astrocytes; Binding, Competitive; Biological Transport; Calcimycin; Calcium; Calcium-Transporting ATPases; Calmodulin; Diglycerides; Enzyme Activation; Kinetics; Protein Kinase C; Rats; Taurine; Tetradecanoylphorbol Acetate; Thapsigargin | 1996 |
Calcium ionophore-induced secretion from mast cells correlates with myosin light chain phosphorylation by protein kinase C.
Topics: Animals; Binding Sites; Calcimycin; Cell Line; Drug Interactions; Histamine Release; Ionophores; Isoenzymes; Mast Cells; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1996 |
Classical second messengers are not involved in proteinase-induced degranulation of airway gland cells.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bradykinin; Calcimycin; Calcium; Cathepsins; Cattle; Cells, Cultured; Chymases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Histamine; Leukocyte Elastase; Protein Kinase C; Second Messenger Systems; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Trachea | 1996 |
Limited T helper cell activity in C57BL/10 (B10) mice with inherited low IgG responsiveness.
Topics: Animals; Antibody Formation; Antigen Presentation; Antigens; Calcimycin; Calcium; Chickens; Egg Proteins; Immunization; Immunoglobulin G; Interleukin-2; Interleukin-3; Interleukin-4; Ionophores; Lipopolysaccharides; Lymphocyte Activation; Lymphocyte Cooperation; Mice; Mice, Inbred A; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Mutant Strains; Muramidase; Protein Kinase C; Signal Transduction; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1996 |
Thyroidal extracellular glutathione peroxidase: a potential regulator of thyroid-hormone synthesis.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Blotting, Western; Brefeldin A; Calcimycin; Cells, Cultured; Culture Media; Cyclopentanes; Electrophoresis, Polyacrylamide Gel; Extracellular Space; Glutathione Peroxidase; Humans; Proteins; Selenoproteins; Sodium Selenite; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyroid Hormones; Thyrotropin | 1995 |
Arachidonic acid metabolism in murine lymphoma cell sublines differing in radiation sensitivity.
Topics: Animals; Arachidonic Acid; Calcimycin; Cell Line; Hydrogen Peroxide; Hydroxyeicosatetraenoic Acids; Ionomycin; Lymphoma; Mice; Phospholipids; Prostaglandins; Radiation Tolerance; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; X-Rays | 1996 |
When do human macrophages release nitric oxide? Variable effects of certain in vitro cultural and in vivo resident conditions.
Topics: Adult; Aged; Animals; Calcimycin; Calcium; Cells, Cultured; Edetic Acid; Female; Humans; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred BALB C; Middle Aged; Nitric Oxide; Protein Kinase C; Rats; Sphingosine; Tetradecanoylphorbol Acetate | 1996 |
Nicotine does not modulate IL-4 and interferon-gamma release from peripheral blood mononuclear cells and T cell clones activated by phorbol myristate acetate and calcium ionophore.
Topics: Calcimycin; Carcinogens; Clone Cells; Enzyme-Linked Immunosorbent Assay; Humans; Hypersensitivity; Immunoglobulin E; Immunophenotyping; Interferon-gamma; Interleukin-4; Ionophores; Leukocytes, Mononuclear; Lymphocyte Activation; Nicotine; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1996 |
Induction of cognate and non-cognate T-cell help for B-cell IgE production in relation to CD40 ligand expression.
Topics: Adult; B-Lymphocytes; Calcimycin; CD40 Antigens; Child; Genetic Linkage; Humans; Hypergammaglobulinemia; Immunoglobulin E; Immunoglobulin M; Ligands; Lymphocyte Activation; Palatine Tonsil; Staphylococcus; Superantigens; Syndrome; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; X Chromosome | 1996 |
Oxygenation activity of chicken blood phagocytes as measured by luminol- and lucigenin-dependent chemiluminescence.
Topics: Acridines; Animals; Calcimycin; Chickens; Luminescent Measurements; Luminol; Oxidation-Reduction; Oxygen; Phagocytes; Respiratory Burst; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Multiple signal transduction systems regulate angiotensin II type 1 (AT1) receptor mRNA expression in bovine adrenocortical cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Cortex; Adrenocorticotropic Hormone; Angiotensin II; Animals; Calcimycin; Cattle; Gene Expression Regulation; Hydrocortisone; Insulin-Like Growth Factor I; Kinetics; Potassium; Receptors, Angiotensin; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Zona Fasciculata | 1996 |
Membrane-stabilizing, anti-inflammatory interactions of macrolides with human neutrophils.
Topics: Adult; Anti-Asthmatic Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Azithromycin; Calcimycin; Cell Membrane; Clarithromycin; Erythromycin; Humans; Ionophores; Luminescent Measurements; Lysophosphatidylcholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Roxithromycin; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Interleukin-1beta-induced inhibition of hair growth in vitro is mediated by cyclic AMP.
Topics: Calcimycin; Cyclic AMP; Hair; Humans; Interleukin-1; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Regulation of neutrophil superoxide generation by alpha-tocopherol in human peripheral and umbilical-cord blood.
Topics: Annexin A1; Calcimycin; Fetal Blood; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Vitamin E | 1996 |
Hck is activated by opsonized zymosan and A23187 in distinct subcellular fractions of human granulocytes.
Topics: Calcimycin; Calcium; Cell Compartmentation; Cell Degranulation; Cell Differentiation; Cells, Cultured; Cytoplasmic Granules; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Opsonin Proteins; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tretinoin; Zymosan | 1997 |
Exocytosis of arginine-specific ADP-ribosyltransferase and p33 induced by A23187 and calcium or serum-opsonized zymosan in chicken polymorphonuclear leukocytes.
Topics: Acetyltransferases; Adenosine Diphosphate Ribose; ADP Ribose Transferases; Animals; Calcimycin; Calcium; Chickens; Dimethyl Sulfoxide; Exocytosis; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Proteins; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Human HMC-1 mast cells exclusively express the Fc gamma RII subtype of IgG receptor.
Topics: Albuterol; Animals; Calcimycin; Calcium; Cell Line; Cross-Linking Reagents; Cytoplasm; Humans; Interferon-gamma; Interleukin-4; Ionophores; Mast Cells; Monocytes; Receptors, IgG; Recombinant Proteins; Stem Cell Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Field trial of a diluent for the transportation of human semen at ambient temperatures.
Topics: Acrosome; Buffers; Calcimycin; Cell Survival; Citric Acid; Egg Yolk; Humans; Luminescent Measurements; Male; N-Formylmethionine Leucyl-Phenylalanine; Oxidative Stress; Preservation, Biological; Reactive Oxygen Species; Semen; Sperm Motility; Spermatozoa; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Transportation | 1997 |
Glucocorticoids regulate both phorbol ester and calcium ionophore-induced endothelial prostacyclin synthesis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Annexins; Anti-Inflammatory Agents; Arachidonic Acid; Calcimycin; Calcium; Cattle; Cells, Cultured; Dexamethasone; Endothelium, Vascular; Epoprostenol; Fura-2; Glucocorticoids; Ionomycin; Ionophores; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1997 |
Molecular cloning and characterization of a novel human receptor protein tyrosine phosphatase gene, hPTP-J: down-regulation of gene expression by PMA and calcium ionophore in Jurkat T lymphoma cells.
Topics: Amino Acid Sequence; Base Sequence; Calcimycin; Calcium; Cloning, Molecular; DNA, Complementary; Down-Regulation; Gene Expression Regulation, Enzymologic; Humans; Ionophores; Jurkat Cells; Lymphocyte Activation; Molecular Sequence Data; Organ Specificity; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Effects of Clostridium botulinum C2 toxin-induced depolymerisation of actin on degranulation of suspended and attached mast cells.
Topics: Actins; Adenosine Diphosphate Ribose; Animals; Botulinum Toxins; Calcimycin; Cell Adhesion; Cell Degranulation; Flow Cytometry; Histamine Release; In Vitro Techniques; Ionophores; Male; Mast Cells; Microscopy, Confocal; p-Methoxy-N-methylphenethylamine; Rats; Rats, Wistar; Serotonin; Tetradecanoylphorbol Acetate | 1997 |
Effects of Clostridium difficile toxin B on activation of rat peritoneal mast cells.
Topics: Animals; Bacterial Proteins; Bacterial Toxins; Calcimycin; Cytotoxins; Dinitrophenols; Flow Cytometry; Glucose; Guanosine 5'-O-(3-Thiotriphosphate); Histamine Release; In Vitro Techniques; Ionophores; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Peritoneal Cavity; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1997 |
Tyrosine phosphorylation of the related adhesion focal tyrosine kinase in megakaryocytes upon stem cell factor and phorbol myristate acetate stimulation and its association with paxillin.
Topics: Binding Sites; Calcimycin; Cell Adhesion Molecules; Cell Line; Cytochalasin D; Cytoskeletal Proteins; Egtazic Acid; Humans; Megakaryocytes; Naphthalenes; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Proline; Protein-Tyrosine Kinases; Proteins; Recombinant Fusion Proteins; Signal Transduction; Stem Cell Factor; Tetradecanoylphorbol Acetate; TYK2 Kinase | 1997 |
Gangliosides involved in activation of rat T lineage cells.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Carbohydrate Sequence; CD4 Antigens; CD8 Antigens; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Gangliosides; Horses; Hybridomas; Interleukin-2; Ionophores; Lymphocyte Activation; Male; Mice; Mice, Inbred C3H; Molecular Sequence Data; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland | 1997 |
Parthenogenetic activation of Chinese hamster oocytes by chemical stimuli and its cytogenetic evaluation.
Topics: Animals; Calcimycin; Cell Division; Chromosomes; Cricetinae; Cricetulus; Cycloheximide; Ethanol; Female; Ionophores; Metaphase; Oocytes; Parthenogenesis; Strontium; Tetradecanoylphorbol Acetate | 1997 |
Ca2+ or phorbol ester but not inflammatory stimuli elevate inducible nitric oxide synthase messenger ribonucleic acid and nitric oxide (NO) release in avian osteoclasts: autocrine NO mediates Ca2+-inhibited bone resorption.
Topics: Animals; Bone and Bones; Bone Resorption; Calcimycin; Calcium; Cells, Cultured; Chickens; Culture Media; Enzyme Activation; Gene Expression; Inflammation Mediators; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Osteoclasts; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1997 |
Abnormalities in CD69 expression, cytosolic pH and Ca2+ during activation of lymphocytes from patients with systemic lupus erythematosus.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; Calcium; Carcinogens; Cell Division; Cytosol; Enzyme Inhibitors; Female; Flow Cytometry; Humans; Hydrogen-Ion Concentration; Interleukin-2; Intracellular Fluid; Ionophores; Lectins, C-Type; Lupus Erythematosus, Systemic; Lymphocyte Activation; Protein Kinase C; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Activation-secretion coupling in 10P2 murine mast cells challenged with IgE-antigen, ionophore A23187, thapsigargin and phorbol ester.
Topics: 2,4-Dinitrophenol; Analysis of Variance; Animals; Antigens; Calcimycin; Carcinogens; Cell Line; Immunization, Passive; Immunoglobulin E; Interleukin-4; Ionophores; Mast Cells; Mice; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Comparative analysis of the ability of precursor germ cells and epididymal spermatozoa to generate reactive oxygen metabolites.
Topics: Animals; Calcimycin; Epididymis; Guinea Pigs; Luminescent Measurements; Male; Mice; NADP; Rats; Reactive Oxygen Species; Species Specificity; Spermatozoa; Testis; Tetradecanoylphorbol Acetate | 1997 |
Tumor cell-endothelial cell interactions: evidence for roles for lipoxygenase products of arachidonic acid in metastasis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Calcimycin; Cattle; Cell Adhesion; Endothelium, Vascular; Humans; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Metastasis; Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
The negative signaling molecule SH2 domain-containing inositol-polyphosphate 5-phosphatase (SHIP) binds to the tyrosine-phosphorylated beta subunit of the high affinity IgE receptor.
Topics: Amino Acid Sequence; Animals; Calcimycin; Calcium; Carcinogens; Down-Regulation; Enzyme Precursors; Intracellular Signaling Peptides and Proteins; Ionophores; Molecular Sequence Data; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Conformation; Protein-Tyrosine Kinases; Rats; Receptors, IgE; src Homology Domains; Syk Kinase; Tetradecanoylphorbol Acetate; Tyrosine | 1997 |
Expression of beta 2-integrins and L-selectin on polymorphonuclear leukocytes in septic patients.
Topics: Adult; Aged; Aged, 80 and over; Calcimycin; CD18 Antigens; Female; Humans; L-Selectin; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sepsis; Severity of Illness Index; Survivors; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1997 |
Dual effects of auranofin on prostaglandin E2 production by rat peritoneal macrophages.
Topics: Animals; Antirheumatic Agents; Arachidonic Acid; Auranofin; Calcimycin; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; In Vitro Techniques; Ionophores; Isoenzymes; Macrophages, Peritoneal; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Adaptive regulation of taurine and beta-alanine uptake in a human kidney cell line from the proximal tubule.
Topics: Adaptation, Physiological; beta-Alanine; Biological Transport; Calcimycin; Cell Line; Colchicine; Humans; Kidney Tubules, Proximal; Kinetics; Signal Transduction; Taurine; Tetradecanoylphorbol Acetate | 1997 |
Cytosolic phospholipase A2 is coupled to muscarinic receptors in the human astrocytoma cell line 1321N1: characterization of the transducing mechanism.
Topics: Arachidonic Acid; Astrocytoma; Brain Neoplasms; Calcimycin; Calcium; Carbachol; Carcinogens; Cytosol; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ionophores; Phospholipases A; Phospholipases A2; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1997 |
Activation of protein kinase C enhances the infection of endothelial cells by human cytomegalovirus.
Topics: Calcimycin; Cells, Cultured; Colforsin; Cytomegalovirus; Endothelium, Vascular; Enzyme Activation; Humans; Iloprost; Okadaic Acid; Protein Kinase C; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Umbilical Veins | 1997 |
Functional dissociation between glucocorticoid-induced decrease in arachidonic acid release and inhibition of adrenocorticotropic hormone secretion in AtT-20 corticotrophs.
Topics: Adrenocorticotropic Hormone; Animals; Arachidonic Acid; Calcimycin; Cell Line; Corticotropin-Releasing Hormone; Dexamethasone; Dose-Response Relationship, Drug; Glucocorticoids; Isoproterenol; Melitten; Mice; Pituitary Gland; Potassium Chloride; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of lung surfactant secretion from alveolar type II cells and annexin II tetramer-mediated membrane fusion by phenothiazines.
Topics: Adenosine Triphosphate; Animals; Annexin A2; Bronchodilator Agents; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Liposomes; Male; Membrane Fusion; Phenothiazines; Phosphatidylcholines; Phospholipids; Promethazine; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Terbutaline; Tetradecanoylphorbol Acetate; Trifluoperazine | 1997 |
Mechanism of the morphological changes induced by staurosporine in rat osteoblasts.
Topics: Actin Cytoskeleton; Actins; Animals; Animals, Newborn; Calcimycin; Calcium; Carcinogens; Cells, Cultured; Cytochalasins; Diglycerides; Enzyme Inhibitors; Fluorescent Dyes; Ionophores; Microtubules; Osteoblasts; Protein Kinase C; Rats; Rats, Wistar; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Vimentin | 1997 |
Inhibitory action of sphingosine or ceramide on amylase secretion from isolated rat pancreatic acini.
Topics: Amylases; Animals; Calcimycin; Carbachol; In Vitro Techniques; Male; Pancreas; Rats; Rats, Wistar; Sincalide; Sodium Fluoride; Sphingosine; Tetradecanoylphorbol Acetate | 1997 |
Modulation of intestinal paracellular permeability by intracellular mediators and cytoskeleton.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Colchicine; Cyclic AMP; Cytochalasins; Cytoskeleton; Enzyme Activation; Gallic Acid; In Vitro Techniques; Intestinal Mucosa; Ionophores; Jejunum; Male; Mannitol; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1997 |
Effect of phorbol myristate acetate (PMA) and ionophore A23187 on interleukin-2 levels and proliferation of activated T lymphocytes from patients with lepromatous leprosy.
Topics: Adult; Aged; Calcimycin; Cell Division; Cells, Cultured; Female; Humans; Interleukin-2; Leprosy, Lepromatous; Lymphocyte Activation; Male; Middle Aged; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Circular ruffle formation in rat basophilic leukemia cells in response to antigen stimulation.
Topics: Actin Cytoskeleton; Actins; Animals; Antigens; Calcimycin; Cell Membrane; Intermediate Filaments; Leukemia, Basophilic, Acute; Mast Cells; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Microtubules; Myosins; Rats; Receptors, IgE; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Of the GATA-binding proteins, only GATA-4 selectively regulates the human IL-5 gene promoter in IL-5 producing cells which express multiple GATA-binding proteins.
Topics: Base Sequence; Binding Sites; Calcimycin; Cell Line; DNA-Binding Proteins; GATA2 Transcription Factor; GATA3 Transcription Factor; GATA4 Transcription Factor; Humans; Interleukin-5; Promoter Regions, Genetic; Recombinant Proteins; Regulatory Sequences, Nucleic Acid; Repetitive Sequences, Nucleic Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Zinc Fingers | 1997 |
Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine.
Topics: Acridines; Calcimycin; Cell Membrane; Cell Movement; Cytochrome c Group; Enzyme Inhibitors; Hot Temperature; Humans; Luminescent Measurements; Male; NAD; NADP; Onium Compounds; Quinacrine; Reactive Oxygen Species; Spermatozoa; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Cystic fibrosis gene mutation (deltaF508) is associated with an intrinsic abnormality in Ca2+-induced arachidonic acid release by epithelial cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Calcium; Cells, Cultured; Chlorides; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Humans; Ibuprofen; Lipoprotein Lipase; Mutation; Phospholipases A; Phospholipases A2; Precipitin Tests; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Functional characterization of equine neutrophils in response to calcium ionophore A23187 and phorbol myristate acetate ex vivo.
Topics: Animals; Calcimycin; Cell Aggregation; Cell Degranulation; Enzyme Activation; Horses; In Vitro Techniques; Ionophores; Male; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
N-6 and n-3 polyunsaturated fatty acids stimulate translocation of protein kinase Calpha, -betaI, -betaII and -epsilon and enhance agonist-induced NADPH oxidase in macrophages.
Topics: Calcimycin; Docosahexaenoic Acids; Enzyme Inhibitors; Fatty Acids, Unsaturated; Histones; HL-60 Cells; Humans; Indoles; Ionophores; Isoenzymes; Luminescent Measurements; Macrophages; Maleimides; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Hydrogen peroxide-induced phospholipase D activation in rat pheochromocytoma PC12 cells: possible involvement of Ca2+-dependent protein tyrosine kinase.
Topics: Animals; Benzoquinones; Blotting, Western; Calcimycin; Calcium; Cinnamates; Enzyme Activation; Enzyme Inhibitors; Genistein; Hydrogen Peroxide; Isoflavones; Lactams, Macrocyclic; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sulfides; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Secretion of proinflammatory cytokines by human conjunctival epithelial cells.
Topics: Calcimycin; Cell Culture Techniques; Conjunctiva; Culture Media; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Epithelium; Escherichia coli; Fluorescent Antibody Technique, Indirect; Humans; Interleukin-1; Keratins; Lipopolysaccharides; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Triple synergism of human T-lymphotropic virus type 1-encoded tax, GATA-binding protein, and AP-1 is required for constitutive expression of the interleukin-5 gene in adult T-cell leukemia cells.
Topics: Calcimycin; Cyclosporine; DNA-Binding Proteins; GATA4 Transcription Factor; Gene Expression Regulation, Viral; Gene Products, tax; Human T-lymphotropic virus 1; Humans; Immunosuppressive Agents; Interleukin-5; Ionophores; Leukemia, T-Cell; Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 1997 |
Protein kinase C- and Ca2+ ionophore-stimulated production of reactive oxygen species in mechanically dispersed isolated bovine luteal cells.
Topics: Animals; Calcimycin; Calcium; Cattle; Cell Count; Cell Separation; Corpus Luteum; Enzyme Activation; Female; Luminescent Measurements; Luteal Phase; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1997 |
Reorganization of the cortical actin cytoskeleton during maturation division in the Tubifex egg: possible involvement of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; Actins; Animals; Calcimycin; Calcium; Cell Size; Chelating Agents; Cytoskeleton; Egtazic Acid; Enzyme Inhibitors; Fluorescent Dyes; Ionophores; Meiosis; Microinjections; Microscopy, Fluorescence; Oligochaeta; Oocytes; Protein Kinase C; Spectrophotometry; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Cellular redistribution of protein tyrosine phosphatases LAR and PTPsigma by inducible proteolytic processing.
Topics: Amino Acid Sequence; Animals; Calcimycin; Calcium; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Membrane; Cytoskeletal Proteins; Desmoplakins; Desmosomes; Egtazic Acid; gamma Catenin; HeLa Cells; Humans; Intercellular Junctions; Isoenzymes; Molecular Sequence Data; Protein Kinase C; Protein Kinase C-alpha; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Calcium and protein kinase C play a significant role in response to Shigella toxin in rabbit ileum both in vivo and in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bacterial Toxins; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Electrolytes; Ileum; Indomethacin; Inositol Phosphates; Male; Neutralization Tests; Prostaglandins E; Protein Kinase C; Rabbits; Shiga Toxins; Tetradecanoylphorbol Acetate; Verapamil | 1997 |
Ammonia effect on calcium-activated chloride secretion in T84 intestinal epithelial monolayers.
Topics: Ammonia; Barium; Calcimycin; Calcium; Carbachol; Cell Line; Chlorides; Colforsin; Cyclic AMP; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Intestinal Mucosa; Intracellular Membranes; Ionomycin; Ionophores; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Roles for protein kinase C and mitogen-activated protein kinase in nicotine-induced secretion from bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Animals; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chromaffin Cells; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Flavonoids; Indoles; Kinetics; Maleimides; Nicotine; Norepinephrine; Potassium Chloride; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1997 |
Stimulation of brook trout ovarian steroidogenesis by gonadotropins I and II is mediated by the cyclic adenosine 3',5'-monophosphate/protein kinase A pathway.
Topics: Animals; Calcimycin; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Estradiol; Female; Gonadotropins, Pituitary; Hydroxyprogesterones; Ionophores; Naphthalenes; Ovarian Follicle; Ovary; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Trout | 1997 |
Effect of the protein kinase C inhibitor GF 109 203X on elastase release and respiratory burst of human neutrophils.
Topics: Calcimycin; Calcium; Enzyme Inhibitors; Exocytosis; Humans; In Vitro Techniques; Indoles; L-Lactate Dehydrogenase; Leukocyte Elastase; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Mechanism of action of two new pyrimidoquinoline and isoquinoline derivatives in human platelets.
Topics: Adenosine Diphosphate; Calcimycin; Collagen; Cyclic AMP; Humans; Ionophores; Isoquinolines; Platelet Aggregation Inhibitors; Quinolones; Tetradecanoylphorbol Acetate | 1997 |
Vitamin E (alpha-tocopherol) enhances arachidonic acid release in rat heart myoblastic cells through the activation of cytosolic phospholipase A2.
Topics: Animals; Arachidonic Acid; Calcimycin; Cytosol; Enzyme Activation; Enzyme Inhibitors; Heart; Indoles; Ionophores; Isoenzymes; Muscle Proteins; Myocardium; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Vitamin E | 1997 |
Regulation of cytosolic phospholipase A2 in arachidonic acid release of rat-liver macrophages.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cytosol; Diglycerides; Enzyme Activation; Ionophores; Isoenzymes; Lipopolysaccharides; Lipoprotein Lipase; Liver; Macrophages; Male; Membrane Lipids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Zymosan | 1997 |
Formation of eicosanoids during differentiation of THP-1 cells.
Topics: Calcimycin; Cell Differentiation; Cholecalciferol; Dinoprostone; Eicosanoids; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Leukemia, Monocytic, Acute; Lipopolysaccharide Receptors; Lipopolysaccharides; Macrophage-1 Antigen; Neoplasm Proteins; Phagocytosis; Phospholipases A; Superoxides; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Parathyroid hormone (1-34)-mediated interleukin-6 induction.
Topics: Becaplermin; Calcimycin; Colforsin; Dinoprostone; Drug Interactions; Gene Expression; Humans; Interleukin-1; Interleukin-6; Osteosarcoma; Plasmids; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Proto-Oncogene Proteins c-sis; Recombinant Fusion Proteins; Teriparatide; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1997 |
Tocopherol modulates the effects of A23187, verapamil, and phorbol myristate acetate on RNA-polymerase activity of isolated rat liver nuclei.
Topics: Animals; Calcimycin; Calcium Channel Blockers; Carrier Proteins; Cell Nucleus; DNA-Directed RNA Polymerases; Female; In Vitro Techniques; Ionophores; Liver; Rats; Tetradecanoylphorbol Acetate; Verapamil; Vitamin E; Vitamin E Deficiency | 1997 |
Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation.
Topics: Actin Depolymerizing Factors; Actins; Amino Acid Sequence; Animals; Calcimycin; Cell Membrane; Diglycerides; Diterpenes; Guinea Pigs; Humans; Hydrogen Peroxide; Immunoblotting; Marine Toxins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Okadaic Acid; Oxazoles; Oxides; Phosphorylation; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 1997 |
Phorbol ester and calcium regulation of corticotrophin-releasing factor receptor 1 expression in a neuronal cell line.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcimycin; Calcium; Carbachol; Cell Line; Corticotropin-Releasing Hormone; Down-Regulation; Egtazic Acid; Enzyme Inhibitors; Kinetics; Mice; Nifedipine; Phenanthridines; Protein Kinase C; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription, Genetic | 1997 |
Activation of protein kinase C induces cortical granule exocytosis in a Ca(2+)-independent manner, but not the resumption of cell cycle in porcine eggs.
Topics: Animals; Calcimycin; Calcium; Cell Cycle; Diglycerides; Enzyme Activation; Exocytosis; Female; In Vitro Techniques; Ionophores; Meiosis; Microscopy, Electron; Oocytes; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate | 1997 |
Azurophilic granules of human neutrophils contain CD14.
Topics: Calcimycin; Cytoplasmic Granules; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate | 1997 |
Effects of PKC alpha activation on Ca2+ pump and K(Ca) channel in deoxygenated sickle cells.
Topics: Anemia, Sickle Cell; Arachidonic Acid; Calcimycin; Calcium; Calcium-Transporting ATPases; Chromatography, DEAE-Cellulose; Cytosol; Diglycerides; Egtazic Acid; Enzyme Activation; Erythrocyte Membrane; Erythrocytes; Humans; In Vitro Techniques; Isoenzymes; Kinetics; Molecular Weight; Protein Kinase C; Protein Kinase C-alpha; Reference Values; Tetradecanoylphorbol Acetate | 1997 |
Cholecystokinin-stimulated tyrosine phosphorylation of p125FAK and paxillin is mediated by phospholipase C-dependent and -independent mechanisms and requires the integrity of the actin cytoskeleton and participation of p21rho.
Topics: Actins; Animals; Calcimycin; Calcium; Cell Adhesion Molecules; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Indoles; Inositol Phosphates; Kinetics; Male; Maleimides; Models, Biological; Pancreas; Paxillin; Phospholipases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; rho GTP-Binding Proteins; Sincalide; Tetradecanoylphorbol Acetate; Tyrosine | 1997 |
Lyn and Fgr are activated in distinct membrane fractions of human granulocytic cells.
Topics: Blotting, Western; Calcimycin; Cell Membrane; Cells, Cultured; Granulocytes; Humans; N-Formylmethionine Leucyl-Phenylalanine; NADP; Neutrophils; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Signal Transduction; src-Family Kinases; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tretinoin; Zymosan | 1997 |
The HMC-1 human mast cell line expresses the hepatocyte growth factor receptor c-met.
Topics: Calcimycin; Hepatoblastoma; Humans; Leukemia, Mast-Cell; Liver Neoplasms; Proto-Oncogene Mas; Proto-Oncogene Proteins c-met; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Acute, nongenomic actions of the neuroactive gonadal steroid, 3 alpha-hydroxy-4-pregnen-20-one (3 alpha HP), on FSH release in perifused rat anterior pituitary cells.
Topics: 20-alpha-Dihydroprogesterone; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium Channel Agonists; Cells, Cultured; Estradiol; Female; Follicle Stimulating Hormone; GABA Modulators; Gonadotropin-Releasing Hormone; Ionophores; Perfusion; Pituitary Gland, Anterior; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Serum Albumin; Tetradecanoylphorbol Acetate; Time Factors; Type C Phospholipases | 1997 |
Relocation of annexin V to platelet membranes is a phosphorylation-dependent process.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Annexin A5; Biological Transport; Blood Platelets; Calcimycin; Cell Compartmentation; Humans; Membranes; Okadaic Acid; Phosphoproteins; Phosphorylation; Platelet Activation; Protein Binding; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Activation of T-cells through an antigen-independent alternative pathway induces precocious sensitivity to Fas-induced apoptosis.
Topics: Adult; Antibodies, Monoclonal; Antibody Specificity; Antigens; Apoptosis; Calcimycin; Cell Division; fas Receptor; Humans; Interleukin-2; Kinetics; Lymphocyte Activation; Phytohemagglutinins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Bradykinin-stimulated arachidonic acid release from MDCK cells is not protein kinase C dependent.
Topics: Animals; Arachidonic Acid; Blotting, Western; Bradykinin; Calcimycin; Cell Line; Dogs; Drug Synergism; Enzyme Inhibitors; Indoles; Kidney; Kinetics; Maleimides; Phospholipases A; Phospholipases A2; Phosphorylation; Phosphoserine; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Direct visualization of the translocation of the gamma-subspecies of protein kinase C in living cells using fusion proteins with green fluorescent protein.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Calcimycin; Calcium; CHO Cells; COS Cells; Cricetinae; Cytochalasin D; Glioma; Green Fluorescent Proteins; Hybrid Cells; Isoenzymes; Kinetics; Luminescent Proteins; Mice; Microscopy, Confocal; Molecular Sequence Data; Neuroblastoma; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection | 1997 |
MAP and cdc2 kinase activities at germinal vesicle breakdown in Chaetopterus.
Topics: Animals; Blotting, Western; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Enzyme Activation; Enzyme Inhibitors; Fertilization; Flavonoids; Glycogen Synthase Kinase 3; Ionophores; Kinetin; MAP Kinase Kinase 1; Meiosis; Mitogen-Activated Protein Kinase Kinases; Oocytes; Phosphorylation; Phosphotyrosine; Polychaeta; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Purines; Tetradecanoylphorbol Acetate | 1997 |
Ursodeoxycholic acid enhances glucocorticoid-induced tyrosine aminotransferase-gene expression in cultured rat hepatocytes.
Topics: Animals; Biomarkers; Calcimycin; Cells, Cultured; Dactinomycin; Dexamethasone; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Ionophores; Liver; Male; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, Glucocorticoid; RNA, Messenger; Sphingosine; Tetradecanoylphorbol Acetate; Tyrosine Transaminase; Up-Regulation; Ursodeoxycholic Acid | 1997 |
Effect of vasoactive intestinal peptide (VIP) on cytokine production and expression of VIP receptors in thymocyte subsets.
Topics: Animals; Base Sequence; Calcimycin; Cells, Cultured; Female; Gene Expression Regulation, Developmental; Interleukin-2; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; Receptors, Vasoactive Intestinal Peptide; RNA, Messenger; Signal Transduction; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1997 |
Neuromedin B receptor activation causes tyrosine phosphorylation of p125FAK by a phospholipase C independent mechanism which requires p21rho and integrity of the actin cytoskeleton.
Topics: Actin Cytoskeleton; Actins; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcimycin; Calcium; Cell Adhesion Molecules; Colchicine; Cytochalasin D; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gastrin-Releasing Peptide; GTP-Binding Proteins; Indoles; Maleimides; Mice; Neurokinin B; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Bombesin; rho GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tumor Cells, Cultured; Type C Phospholipases; Tyrphostins | 1997 |
[Metronidazole effect on active oxygen production by human blood neutrophils].
Topics: Antitrichomonal Agents; Calcimycin; Dose-Response Relationship, Drug; Free Radical Scavengers; Glucose Oxidase; Humans; Ionophores; Luminescent Measurements; Metronidazole; Neutrophils; Peroxidases; Reactive Oxygen Species; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Zymosan | 1997 |
Regulation of leukotriene and platelet-activating factor synthesis in human alveolar macrophages.
Topics: Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Arachidonic Acids; Asthma; Benzenesulfonates; Bronchoalveolar Lavage Fluid; Calcimycin; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; Humans; Ionophores; Leukotriene B4; Leukotrienes; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Urea | 1997 |
Bradykinin-stimulated cPLA2 phosphorylation is protein kinase C dependent in rabbit CCD cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Cells, Cultured; Cyclohexanones; Cytosol; Enzyme Inhibitors; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Phospholipases A; Phospholipases A2; Phosphorylation; Protease Inhibitors; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1997 |
Cell-mediated immunosuppression in mice by street rabies virus not restored by calcium ionophore or PMA.
Topics: Animals; Calcimycin; Calcium; Cations, Divalent; Cytosol; Cytotoxicity, Immunologic; Dogs; Immunity, Cellular; Immunosuppression Therapy; Interleukin-2; L Cells; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mitogens; Protein Kinase C; Rabies; Rabies virus; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Inhibition of tumor cell growth by murine splenic adherent cells stimulated with IFN-gamma.
Topics: Animals; Antineoplastic Agents; Calcimycin; Cell Division; Cell Survival; Female; Humans; Interferon-gamma; Lipopolysaccharides; Lymphoma, T-Cell; Macrophage Activation; Macrophages; Membrane Lipids; Mice; Mice, Inbred DBA; Spleen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Effects of bryostatin 1 and calcium ionophore (A23187) on apoptosis and differentiation in human myeloid leukemia cells (HL-60) following 1-beta-D-arabinofuranosylcytosine exposure.
Topics: Acetamides; Antineoplastic Agents; Apoptosis; Bryostatins; Calcimycin; Calcium; Cell Differentiation; Cytarabine; DNA Fragmentation; HL-60 Cells; Humans; Lactones; Macrolides; Tetradecanoylphorbol Acetate | 1998 |
ATP-induced arachidonic acid release in cultured astrocytes is mediated by Gi protein coupled P2Y1 and P2Y2 receptors.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Astrocytes; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; GTP-Binding Protein alpha Subunits, Gi-Go; Immunoblotting; Ionophores; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Tetradecanoylphorbol Acetate | 1998 |
Synthesis, storage, and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF206.
Topics: Blotting, Western; Calcimycin; Culture Media, Conditioned; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Leukemia; Lymphokines; Mast Cells; Microscopy, Immunoelectron; Polymerase Chain Reaction; Skin; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Mechanisms regulating prostaglandin F2 alpha secretion from the bovine endometrium.
Topics: Animals; Calcimycin; Calcium; Cattle; Dinoprost; Endometrium; Enzyme Activation; Female; Inositol 1,4,5-Trisphosphate; Oxytocin; Pregnancy; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Modulation of chloride secretion across the pigmented rabbit conjunctiva.
Topics: Animals; Calcimycin; Calcium; Chlorides; Conjunctiva; Cyclic AMP; Drug Combinations; Male; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1998 |
Metabolism of phosphatidylcholine in mouse pancreatic islets.
Topics: Adenosine Triphosphate; Aluminum Chloride; Aluminum Compounds; Animals; Calcimycin; Cells, Cultured; Chlorides; Choline; Colforsin; Glucose; Islets of Langerhans; Kinetics; Male; Mice; Mice, Inbred Strains; Phosphatidylcholines; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1997 |
Shigella dysenteriae type 1 toxin induced lipid peroxidation in enterocytes isolated from rabbit ileum.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Bacterial Toxins; Calcimycin; Calcium Channel Blockers; Dantrolene; Dysentery, Bacillary; Enterotoxins; Enzyme Inhibitors; Ileum; In Vitro Techniques; Indomethacin; Ionophores; Lipid Peroxides; Male; Muscle Relaxants, Central; Rabbits; Reactive Oxygen Species; Shiga Toxins; Shigella dysenteriae; Tetradecanoylphorbol Acetate; Verapamil | 1998 |
Regulation of eicosanoid synthesis in liver macrophages.
Topics: Animals; Calcimycin; Calcium; Diglycerides; Dinoprostone; Eicosanoids; Inositol Phosphates; Kinetics; Kupffer Cells; Models, Biological; Sodium Fluoride; Tetradecanoylphorbol Acetate; Zymosan | 1997 |
Regulation of arachidonic acid release and metabolism by tumor promoters.
Topics: Animals; Animals, Newborn; Arachidonic Acid; Bradykinin; Calcimycin; Carcinogens; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Inflammation; Isoenzymes; Kinetics; Membrane Proteins; Mice; Mice, Inbred Strains; Phospholipases A; Prostaglandin-Endoperoxide Synthases; Protein Biosynthesis; Proteins; Skin; Tetradecanoylphorbol Acetate | 1997 |
Identification and characterization of several forms of phospholipase A2 in mouse epidermal keratinocytes.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Cell Line; Cell Membrane; Cytosol; Enzyme Activation; Epidermal Cells; Hot Temperature; Isoenzymes; Keratinocytes; Kinetics; Linoleic Acid; Mice; Oleic Acid; Phospholipases A; Phospholipases A2; Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate | 1998 |
Characterization of proteins binding the 3' regulatory region of the IL-3 gene in IL-3-dependent and autocrine-transformed hematopoietic cells.
Topics: Adenine; Animals; Base Sequence; Calcimycin; Calcium; Hematopoietic Stem Cells; Humans; Interleukin-3; Ionophores; Mice; Regulatory Sequences, Nucleic Acid; Ribonucleoproteins; RNA Probes; RNA-Binding Proteins; RNA, Messenger; Substrate Specificity; Tetradecanoylphorbol Acetate; Transformation, Genetic; Uracil | 1998 |
Glucagon-like peptide-1-(7-36)amide increases pulmonary surfactant secretion through a cyclic adenosine 3',5'-monophosphate-dependent protein kinase mechanism in rat type II pneumocytes.
Topics: Adrenergic beta-Agonists; Animals; Calcimycin; Calcium-Transporting ATPases; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Kinetics; Lung; Male; Peptide Fragments; Phosphatidylcholines; Pulmonary Surfactants; Rats; Rats, Wistar; Terbutaline; Tetradecanoylphorbol Acetate; Thapsigargin | 1998 |
Protein kinase C alterations in aortic vascular smooth muscle cells from rats with cirrhosis.
Topics: Animals; Aorta, Thoracic; Calcimycin; Calcium; Culture Media; In Vitro Techniques; Ionophores; Liver Cirrhosis, Experimental; Male; Muscle, Smooth, Vascular; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Vasoconstriction | 1998 |
Myoblasts produce IL-6 in response to inflammatory stimuli.
Topics: Adenylyl Cyclases; Calcimycin; Cells, Cultured; Humans; Inflammation; Interleukin-1; Interleukin-6; Muscles; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
In vitro interaction between spiramycin and polymorphonuclear neutrophils oxidative metabolism.
Topics: Anti-Bacterial Agents; Blood Bactericidal Activity; Calcimycin; Cell Survival; Enzyme Activation; Humans; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Reactive Oxygen Species; Spiramycin; Staphylococcus aureus; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Sperm capacitation is, after all, a prerequisite for both partial and complete acrosome reaction.
Topics: Acrosome; Calcimycin; Culture Media; Humans; Ionophores; Male; Serum Albumin, Bovine; Sperm Capacitation; Tetradecanoylphorbol Acetate | 1998 |
Stimulation of prohormone convertase-1 mRNA expression by second messenger signaling systems.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Aspartic Acid Endopeptidases; Calcimycin; Calcium; Cell Line; Cyclic AMP; Enzyme Activation; Gene Expression; Humans; Ionophores; Neurosecretory Systems; Neurotensin; Proprotein Convertases; Protein Kinase C; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Up-Regulation | 1998 |
Comparative cytokine gene expression: regulation and release by human mast cells.
Topics: Calcimycin; Cytokines; Gene Expression Regulation; Humans; Interleukin-6; Interleukin-8; Mast Cells; Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Identification of a 57-kilodalton selenoprotein in human thyrocytes as thioredoxin reductase and evidence that its expression is regulated through the calcium-phosphoinositol signaling pathway.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Calcimycin; Calcium; Cells, Cultured; Humans; Ionophores; Kinetics; Phosphatidylinositols; Signal Transduction; Tetradecanoylphorbol Acetate; Thioredoxin-Disulfide Reductase; Thyroid Gland; Thyrotropin | 1998 |
Anti-inflammatory effect of YPE-01, a novel diarylheptanoid derivative, on dermal inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Chemotactic Factors; Chromatography, High Pressure Liquid; Diarylheptanoids; Ear; Edema; Hydroxyeicosatetraenoic Acids; Ionophores; Ketones; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred ICR; Phenols; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway.
Topics: Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; CD28 Antigens; CD3 Complex; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Imidazoles; Interleukin-2; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Lymphocyte Activation; MAP Kinase Kinase 1; MAP Kinase Kinase 7; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; RNA, Messenger; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transgenes | 1998 |
Role of protein kinases in regulation of apical secretion and basal-lateral membrane recycling traffic in reconstituted rabbit lacrimal gland acini.
Topics: Animals; beta-N-Acetylhexosaminidases; Calcimycin; Carbachol; Cells, Cultured; Endocytosis; Enzyme Inhibitors; Eye Proteins; Female; Homeostasis; Lacrimal Apparatus; Naphthalenes; Protein Kinases; Rabbits; Tetradecanoylphorbol Acetate | 1998 |
An anergic cytotoxic T lymphocyte clone exhibits granule exocytosis-mediated cytotoxicity.
Topics: Animals; Calcimycin; Clonal Anergy; Clone Cells; Cytoplasmic Granules; Cytotoxicity, Immunologic; Exocytosis; Fas Ligand Protein; fas Receptor; Granzymes; Ligands; Mast-Cell Sarcoma; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Perforin; Pore Forming Cytotoxic Proteins; RNA, Messenger; Serine Endopeptidases; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Distinct phospholipase C-regulated signalling pathways in Swiss 3T3 fibroblasts induce the rapid generation of the same polyunsaturated diacylglycerols.
Topics: 3T3 Cells; Animals; Brain; Calcimycin; Calcium; Diglycerides; Dinoprost; Enzyme Activation; Fibroblasts; Ionophores; Mice; Phosphatidate Phosphatase; Phosphatidylcholines; Phospholipase D; Platelet-Derived Growth Factor; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1998 |
Dependence of neutrophil activation on cell density and adhesion.
Topics: Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Calcium; Cell Adhesion; Cell Count; Cells, Cultured; Drug Synergism; Humans; Hydrogen-Ion Concentration; Hydroxyeicosatetraenoic Acids; Ionophores; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Respiratory Burst; Signal Transduction; Tetradecanoylphorbol Acetate | 1998 |
Role of intracellular second messengers and reactive oxygen species in the pathophysiology of V. cholera O139 treated rabbit ileum.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Calcimycin; Calcium; Calcium Channel Blockers; Cholera; Cyclic AMP; Dantrolene; Enzyme Activation; Ileum; Inositol Phosphates; Ionophores; Lipid Peroxidation; Protein Kinase C; Rabbits; Reactive Oxygen Species; Second Messenger Systems; Tetradecanoylphorbol Acetate; Verapamil; Water-Electrolyte Balance | 1998 |
Comparative morphofunctional study of dispersed mature canine cutaneous mast cells and BR cells, a poorly differentiated mast cell line from a dog subcutaneous mastocytoma.
Topics: Animals; Calcimycin; Cell Separation; Concanavalin A; Dog Diseases; Dogs; Histamine; Histamine Release; In Vitro Techniques; Ionophores; Mast Cells; Mast-Cell Sarcoma; Microscopy, Electron; p-Methoxy-N-methylphenethylamine; Receptors, IgE; Substance P; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Selective modulation of MAP kinase in embryonic palate cells.
Topics: Animals; Calcimycin; Carcinogens; Cells, Cultured; Cholera Toxin; Cyclic AMP; Endothelial Growth Factors; Enzyme Activation; Enzyme Inhibitors; Fetus; Flavonoids; Ionophores; Isoquinolines; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Palate; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1998 |
Processing and release of tumor necrosis factor alpha.
Topics: 3T3 Cells; Animals; Bucladesine; Calcimycin; Cell Line; Cloning, Molecular; Culture Media; Gene Expression Regulation; Humans; Kinetics; Mice; Monocytes; Recombinant Proteins; Serine Endopeptidases; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 1998 |
Coexpression of phospholipase A2 isoforms in rat striatal astrocytes.
Topics: Animals; Arachidonic Acid; Astrocytes; Calcimycin; Corpus Striatum; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Ionophores; Isoenzymes; Nerve Tissue Proteins; Phospholipases A; Phospholipases A2; Polymerase Chain Reaction; Protein Kinase C; Quinacrine; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 1998 |
Stimulus-dependent transduction mechanisms for nitric oxide release in human polymorphonuclear neutrophil leukocytes.
Topics: Calcimycin; Calcium; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Release of a leukocyte activation inhibitor by staurosporine-treated pulmonary artery endothelial cells.
Topics: Animals; Biological Factors; Calcimycin; Cattle; Cell Adhesion; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Diethylcarbamazine; Endothelium, Vascular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptidyl-Dipeptidase A; Protein Kinase C; Pulmonary Artery; Rabbits; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Effects of GnRH on protein kinase C activity, Ca2+ mobilization and steroidogenesis of human granulosa cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Calcium; Enzyme Inhibitors; Estradiol; Female; Gonadotropin-Releasing Hormone; Granulosa Cells; Humans; Lipoxygenase Inhibitors; Masoprocol; Progesterone; Protein Kinase C; Steroids; Tetradecanoylphorbol Acetate | 1998 |
Sphingosine modulates interleukin-6 synthesis in osteoblasts.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Dose-Response Relationship, Drug; Fibroblast Growth Factor 2; Immunoenzyme Techniques; Interleukin-1; Interleukin-6; Mice; Osteoblasts; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Inhibition of lung surfactant secretion by KN-62, a specific inhibitor of the calcium- and calmodulin-dependent protein kinase II.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Animals; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ionophores; Male; Phosphatidylcholines; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Terbutaline; Tetradecanoylphorbol Acetate | 1998 |
Lack of direct connection between arachidonic acid release and prostanoid synthesis upon differentiation of U937 cell.
Topics: Arachidonic Acid; Calcimycin; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Dinoprostone; Humans; Ionophores; Monocytes; Prostaglandins; Tetradecanoylphorbol Acetate; Thromboxane B2; Tretinoin | 1998 |
Inhibition of macrophage migration inhibitory factor secretion from macrophages by vitamin E.
Topics: Animals; Calcimycin; Culture Media; Interleukin-6; Lipopolysaccharides; Macrophage Migration-Inhibitory Factors; Macrophages, Peritoneal; Male; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Vitamin E | 1998 |
Mast cells can secrete vascular permeability factor/ vascular endothelial cell growth factor and exhibit enhanced release after immunoglobulin E-dependent upregulation of fc epsilon receptor I expression.
Topics: Animals; Calcimycin; Cell Line; Cells, Cultured; Dinitrophenols; Endothelial Growth Factors; Female; Haptens; Humans; Immunoglobulin E; Lymphokines; Male; Mast Cells; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar; Receptors, IgE; RNA, Messenger; Serum Albumin; Stem Cell Factor; Tetradecanoylphorbol Acetate; Transcription, Genetic; Umbilical Cord; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Role of Glut1 glucose transporter activation in stimulation of glucose transport by A231876 and TPA.
Topics: 3-O-Methylglucose; 3T3 Cells; Adipocytes; Animals; Biological Transport; Calcimycin; Clone Cells; Glucose Transporter Type 1; Mice; Monosaccharide Transport Proteins; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 1998 |
Human mast cells produce IL-13 by high-affinity IgE receptor cross-linking: enhanced IL-13 production by IL-4-primed human mast cells.
Topics: Antibodies, Anti-Idiotypic; Calcimycin; Cells, Cultured; Cytoplasm; Fetal Blood; Humans; Immunoglobulin E; Interleukin-13; Interleukin-4; Ionophores; Kinetics; Mast Cells; Receptors, IgE; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Translocation and phosphorylation of cytosolic phospholipase A2 in activated platelets.
Topics: Arachidonic Acid; Biological Transport, Active; Blood Platelets; Calcimycin; Calcium; Cytosol; Humans; In Vitro Techniques; Ionophores; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin | 1998 |
Endothelial cell "memory" of inflammatory stimulation: human venular endothelial cells store interleukin 8 in Weibel-Palade bodies.
Topics: Calcimycin; Cells, Cultured; Endothelium, Vascular; Golgi Apparatus; Histamine; Humans; Inflammation; Interleukin-1; Interleukin-8; Ionophores; Microscopy, Fluorescence; Microscopy, Immunoelectron; Organelles; Tetradecanoylphorbol Acetate; Umbilical Veins | 1998 |
Involvement of Na+/Ca2+ exchanger in inside-out signaling through the platelet integrin IIbbeta3.
Topics: Amiloride; Bepridil; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Chymotrypsin; Cytoplasmic Granules; Fibrinogen; Humans; Ion Transport; Myosin Light Chains; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Processing, Post-Translational; Serotonin; Signal Transduction; Sodium; Sodium-Calcium Exchanger; Tetradecanoylphorbol Acetate | 1998 |
The effect of calcium-related factors on the predominance of IFN-gamma or interleukin-4 in cultured mononuclear cells.
Topics: Calcimycin; Calcium; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-gamma; Interleukin-4; Ionomycin; Ionophores; Leukocytes, Mononuclear; Phytohemagglutinins; Polymerase Chain Reaction; Risk Factors; Tetradecanoylphorbol Acetate | 1998 |
Interleukin 4 receptors on human bronchial epithelial cells. An in vivo and in vitro analysis of expression and function.
Topics: Asthma; Bronchi; Bucladesine; Calcimycin; Cells, Cultured; Chemokine CCL2; Epithelial Cells; Gene Expression Regulation; Humans; In Situ Hybridization; Intercellular Adhesion Molecule-1; Interleukin 1 Receptor Antagonist Protein; Interleukin-4; Interleukin-8; Interleukins; Receptors, Interleukin-1; Receptors, Interleukin-4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate | 1998 |
Effect of bronchial allergen challenge on in vitro cytokine release by peripheral blood mononuclear cells of atopic patients.
Topics: Adolescent; Adult; Allergens; Asthma; Bronchial Provocation Tests; Calcimycin; Carcinogens; Cytokines; Female; Humans; Interferon-gamma; Interleukin-10; Interleukin-13; Interleukin-4; Interleukin-5; Ionophores; Leukocytes, Mononuclear; Male; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Differential activation of phospholipases during necrosis or apoptosis: a comparative study using tumor necrosis factor and anti-Fas antibodies.
Topics: Animals; Antibodies; Apoptosis; Arachidonic Acid; Calcimycin; Cell Cycle; Enzyme Activation; fas Receptor; Glycerophospholipids; Humans; Mice; Necrosis; Phospholipase D; Phospholipases; Phospholipases A; Phospholipases A2; Phosphorylation; Ploidies; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Receptor (CD46)- and replication-mediated interleukin-6 induction by measles virus in human astrocytoma cells.
Topics: Antigens, CD; Astrocytes; Astrocytoma; Calcimycin; Carrier Proteins; Gene Expression Regulation; Hemagglutinins, Viral; Humans; Interleukin-6; Intracellular Signaling Peptides and Proteins; Measles virus; Membrane Cofactor Protein; Membrane Glycoproteins; Poly I-C; Receptor Aggregation; Receptors, Virus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ultraviolet Rays; Vesicular stomatitis Indiana virus; Viral Envelope Proteins; Viral Fusion Proteins; Virus Replication | 1998 |
Regulation of human renin gene promoter activity: a new negative regulatory region determines the responsiveness to TNF alpha.
Topics: Adrenal Glands; Angiotensin II; Animals; Calcimycin; Cell Line; Colforsin; Cytokines; DNA; Haplorhini; Humans; Ionophores; Mice; Promoter Regions, Genetic; Renin; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 1998 |
Intracellular signaling mechanisms of interleukin-1beta in synovial fibroblasts.
Topics: Animals; Calcimycin; Calcium Channel Blockers; Cell Line; Enzyme Inhibitors; Fibroblasts; Indoles; Interleukin-1; Intracellular Membranes; Ionophores; Maleimides; Nifedipine; Rabbits; Signal Transduction; Synovial Membrane; Tetradecanoylphorbol Acetate; Verapamil | 1999 |
The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells.
Topics: Antibodies, Monoclonal; Antigen-Presenting Cells; Antioxidants; Ascorbic Acid; Calcimycin; CD28 Antigens; Cell Division; Deferoxamine; Dimethyl Sulfoxide; Humans; In Vitro Techniques; Interleukin-2; Ionophores; Lymphocyte Activation; Reactive Oxygen Species; Second Messenger Systems; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1999 |
Regulation of natriuretic peptide (urodilatin) release in a human kidney cell line.
Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Calcimycin; Cell Line; Colforsin; Culture Media; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Humans; Intracellular Fluid; Kidney; Osmolar Concentration; Peptide Fragments; Radioimmunoassay; Tetradecanoylphorbol Acetate | 1999 |
Electron spin resonance detection of extracellular superoxide anion released by cultured endothelial cells.
Topics: Animals; Aorta; Arginine; Calcimycin; Cattle; Cells, Cultured; Culture Media, Conditioned; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Enzyme Inhibitors; Ionophores; NAD; NADP; Nitric Oxide Synthase; Onium Compounds; Rats; Spin Labels; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Redistribution of F-actin and large dense-cored vesicles in the human neuroblastoma SH-SY5Y in response to secretagogues and protein kinase Calpha activation.
Topics: Actins; Calcimycin; Carbachol; Cell Membrane; Down-Regulation; Enzyme Activation; Humans; Ionophores; Isoenzymes; Liposomes; Neuroblastoma; Potassium; Protein Kinase C; Protein Kinase C-alpha; Secretory Rate; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Transforming growth factor-beta isoforms regulate the surface expression of membrane cofactor protein (CD46) and CD59 on human keratinocytes [corrected].
Topics: Antigens, CD; Bucladesine; Calcimycin; CD55 Antigens; CD59 Antigens; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Humans; Keratinocytes; Membrane Cofactor Protein; Membrane Glycoproteins; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Up-Regulation | 1999 |
Contribution of cyclooxygenase-1 and cyclooxygenase-2 to prostanoid formation by human enterocytes stimulated by calcium ionophore and inflammatory agents.
Topics: Calcimycin; Calcium; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Eicosanoids; Epithelial Cells; Humans; Immunoblotting; Interleukin-1; Intestinal Mucosa; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Nitrobenzenes; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Salicylates; Sulfonamides; Tetradecanoylphorbol Acetate | 1998 |
Regulation of lung surfactant secretion by phospholipase A2.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Cinnamates; Cyclohexanones; Diglycerides; Enzyme Inhibitors; Lipoprotein Lipase; Male; ortho-Aminobenzoates; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Terbutaline; Tetradecanoylphorbol Acetate | 1999 |
Intracellular mechanisms of hydrogen peroxide-mediated neutrophil adherence to cultured human endothelial cells.
Topics: Azepines; Calcimycin; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hydrogen Peroxide; In Vitro Techniques; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triazoles | 1999 |
Characterization of a mutant T-cell hybridoma line with defects in the TCR-mediated apoptotic pathway.
Topics: Apoptosis; Calcimycin; Calcium; Calcium Channels; Cell Cycle; Cell Line; Dexamethasone; DNA-Binding Proteins; Fas Ligand Protein; Flow Cytometry; Hybridomas; Immunohistochemistry; Inositol 1,4,5-Trisphosphate Receptors; Interleukin-2; Membrane Glycoproteins; Mutation; Nuclear Receptor Subfamily 4, Group A, Member 1; Receptors, Antigen, T-Cell; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors | 1999 |
Ca2+ and protein kinase C signaling for histamine and sulfidoleukotrienes released from human cultured mast cells.
Topics: Animals; Antibodies; Calcimycin; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Cell Membrane; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Activation; Histamine; Humans; Immunoglobulin E; Leukotrienes; Mast Cells; Protein Kinase C; Rodentia; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Angiotensin II interacts with prostaglandin F2alpha and endothelin-1 as a local luteolytic factor in the bovine corpus luteum in vitro.
Topics: Abortifacient Agents, Nonsteroidal; Angiotensin II; Animals; Calcimycin; Cattle; Corpus Luteum; Dinoprost; Dose-Response Relationship, Drug; Endothelin-1; Female; In Vitro Techniques; Luteolytic Agents; Microdialysis; Pregnancy; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1999 |
TNF-alpha and IL-1alpha induce heme oxygenase-1 via protein kinase C, Ca2+, and phospholipase A2 in endothelial cells.
Topics: Acetylcysteine; Blotting, Northern; Calcimycin; Calcium; Carcinogens; Cells, Cultured; Chelating Agents; Cysteine Proteinase Inhibitors; Dipeptides; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Interleukin-1; Ionophores; Marine Toxins; Membrane Proteins; Okadaic Acid; Oxazoles; Phospholipases A; Phospholipases A2; Protein Kinase C; Reactive Oxygen Species; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins | 1999 |
Synaptotagmin II negatively regulates Ca2+-triggered exocytosis of lysosomes in mast cells.
Topics: Animals; beta-N-Acetylhexosaminidases; Calcimycin; Calcium; Cathepsin D; Cytoplasmic Granules; Exocytosis; Gene Expression Regulation; Lysosomes; Mast Cells; Mice; Mice, Inbred BALB C; Nerve Tissue Proteins; Rats; Rats, Wistar; Receptors, IgE; RNA, Messenger; Serotonin; Synaptotagmin II; Tetradecanoylphorbol Acetate; Transfection | 1999 |
Detection of partial and complete acrosome reaction in human spermatozoa: which inducers and probes to use?
Topics: Acrosome Reaction; Adult; Antigens, CD; Biomarkers; Calcimycin; Female; Fluorescein-5-isothiocyanate; Follicular Fluid; Humans; Ionophores; Lectins; Male; Membrane Cofactor Protein; Membrane Glycoproteins; Plant Lectins; Progesterone; Spermatozoa; Staining and Labeling; Tetradecanoylphorbol Acetate | 1999 |
Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation.
Topics: Air; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Arachidonic Acids; Caffeic Acids; Calcimycin; Carcinoma, Squamous Cell; Carrageenan; Cell Membrane; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Activation; Enzyme Induction; Epithelial Cells; Genetic Vectors; Humans; Indomethacin; Inflammation; Ionophores; Isoenzymes; Male; Membrane Lipids; Membrane Proteins; Mouth Mucosa; Nucleopolyhedroviruses; Phenylethyl Alcohol; Phospholipids; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1999 |
On the use of ionophores as probes for calcium signalling. Observations with rat mast cells.
Topics: Animals; Calcimycin; Calcium; Dimethyl Sulfoxide; Ionomycin; Ionophores; Mast Cells; Rats; Rats, Wistar; Signal Transduction; Solutions; Tetradecanoylphorbol Acetate | 1999 |
Protein kinases A and C are opponents in modulating glial Ca2+ -activated K+ channels.
Topics: Animals; Bucladesine; Calcimycin; Calcium; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Ion Channel Gating; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Neuroglia; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Kinase C; Rabbits; Retina; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1999 |
Modulatory effect of HCO3- on rat mast cell exocytosis: cross-talks between bicarbonate and calcium.
Topics: Animals; Bicarbonates; Calcimycin; Calcium; Chelating Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exocytosis; Histamine Release; Ionophores; Kinetics; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1999 |
Antagonism of p53-dependent apoptosis by mitogen signals.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Calcimycin; Cell Line, Transformed; Cisplatin; Humans; Ionophores; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogens; Phosphatidylinositol 3-Kinases; Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1999 |
Effect of ceramide on interleukin-6 synthesis in osteoblast-like cells.
Topics: Alprostadil; Animals; Bucladesine; Calcimycin; Cell Line; Cholera Toxin; Colforsin; Dinoprost; Interleukin-1; Interleukin-6; Mice; Osteoblasts; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Tumor Necrosis Factor-alpha | 1999 |
Protein kinase C-dependent anti-apoptotic mechanism that is associated with high sensitivity to anti-Fas antibody in ovarian cancer cell lines.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies; Apoptosis; Calcimycin; Cell Division; Ceramides; Cyclic AMP-Dependent Protein Kinases; DNA Fragmentation; Enzyme Inhibitors; fas Receptor; Female; Flow Cytometry; Humans; Isoquinolines; Ovarian Neoplasms; Protein Kinase C; Signal Transduction; Sphingomyelin Phosphodiesterase; Sulfonamides; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1999 |
O-linked N-acetylglucosamine levels in cerebellar neurons respond reciprocally to pertubations of phosphorylation.
Topics: Acetylglucosamine; Animals; Calcimycin; Carbohydrate Conformation; Cells, Cultured; Cerebellum; Enzyme Activation; Enzyme Inhibitors; Mice; Neurons; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Receptor Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate | 1999 |
Abnormal NF-kappa B activity in T lymphocytes from patients with systemic lupus erythematosus is associated with decreased p65-RelA protein expression.
Topics: Autoradiography; Calcimycin; DNA-Binding Proteins; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Lupus Erythematosus, Systemic; Lymphocyte Activation; NF-kappa B; NF-kappa B p50 Subunit; Normal Distribution; Receptors, Antigen, T-Cell; Severity of Illness Index; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor RelA | 1999 |
Tetracycline derivative CMT-3 inhibits cytokine production, degranulation, and proliferation in cultured mouse and human mast cells.
Topics: Animals; Bone Marrow Cells; Calcimycin; Cell Degranulation; Cell Division; Cell Line; Cells, Cultured; Culture Media, Conditioned; Cytokines; Humans; Mast Cells; Mice; Mice, Inbred BALB C; Protease Inhibitors; Tetracyclines; Tetradecanoylphorbol Acetate | 1999 |
Priming effect of calcium ionophores on phorbol ester-induced respiratory burst in mouse peritoneal neutrophils.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Ionomycin; Mice; Neutrophils; Phospholipases A; Phospholipases A2; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate | 1999 |
Thioredoxin reductase is the major selenoprotein expressed in human umbilical-vein endothelial cells and is regulated by protein kinase C.
Topics: Blotting, Western; Calcimycin; Calcium; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Indoles; Maleimides; Molecular Weight; Organ Specificity; Protein Kinase C; Proteins; Selenoproteins; Sodium Selenite; Tetradecanoylphorbol Acetate; Thioredoxin-Disulfide Reductase; Thyroid Gland; Time Factors; Tumor Cells, Cultured; Umbilical Veins | 1999 |
Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by TPA, a calcium ionophore and other tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcimycin; Calcium; Carcinogens; Cocarcinogenesis; Diglycerides; Diterpenes; Enzyme Activation; Enzyme Induction; Epidermis; Female; Fluocinolone Acetonide; Gene Expression Regulation; Glutaredoxins; Glutathione; Ionophores; Mice; Oxidation-Reduction; Oxidoreductases; Phorbol Esters; Protein Kinase C; Proteins; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Thioredoxin-Disulfide Reductase; Thioredoxins; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1999 |
Differential modulation of interleukin-4 and interleukin-13 secretion from human peripheral blood mononuclear cells.
Topics: Calcimycin; Calcium; Dose-Response Relationship, Immunologic; Humans; Interleukin-13; Interleukin-3; Interleukin-4; Ionophores; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocyte Subsets; Phytohemagglutinins; Tetradecanoylphorbol Acetate | 1999 |
Differential phospholipase D activation by bradykinin and sphingosine 1-phosphate in NIH 3T3 fibroblasts overexpressing gelsolin.
Topics: 3T3 Cells; Animals; Bradykinin; Calcimycin; Cell Membrane; DNA, Complementary; Egtazic Acid; Enzyme Activation; Gelsolin; Humans; Isoenzymes; Kinetics; Lysophospholipids; Mice; Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-epsilon; Recombinant Proteins; Sphingosine; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases; Virulence Factors, Bordetella | 1999 |
The activity of the human interleukin-5 conserved lymphokine element 0 is regulated by octamer factors in human cells.
Topics: Base Sequence; Binding Sites; Calcimycin; Cell Line; Conserved Sequence; DNA-Binding Proteins; Gene Expression Regulation; Host Cell Factor C1; Humans; Interleukin-5; Lymphokines; Octamer Transcription Factor-1; Octamer Transcription Factor-2; Promoter Regions, Genetic; Protein Binding; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors | 1999 |
Mast cell tryptase does not alter matrix metalloproteinase expression in human dermal fibroblasts: further evidence that proteolytically-active tryptase is a potent fibrogenic factor.
Topics: Adult; Calcimycin; Cell Line; Chymases; Culture Media, Conditioned; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Gene Expression Regulation, Enzymologic; Heparin; Humans; Lung; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 3; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Mitogens; RNA, Messenger; Serine Endopeptidases; Skin; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Transcription, Genetic; Transforming Growth Factor beta; Tryptases | 1999 |
Calcium and phosphatidylserine stimulate the self-association of conventional protein kinase C isoforms.
Topics: Animals; Calcimycin; Calcium; Cell Line; Cross-Linking Reagents; Dimerization; Enzyme Activation; Epidermal Growth Factor; Fibroblasts; Humans; Isoenzymes; Magnesium; Maleimides; Mice; Phosphatidic Acids; Phosphatidylinositols; Phosphatidylserines; Protein Kinase C; Rats; Substrate Specificity; Tetradecanoylphorbol Acetate | 1999 |
A novel calcium signaling pathway targets the c-fos intragenic transcriptional pausing site.
Topics: 1-Methyl-3-isobutylxanthine; 5' Untranslated Regions; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Calcineurin; Calcium; Calmodulin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Gene Expression Regulation; Genes, fos; Genes, Reporter; Humans; Introns; L Cells; Metallothionein; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Recombinant Fusion Proteins; Serine; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1999 |
Effect of 1,25(OH)(2)-vitamin D(3) on the activation of natural killer cells: role of protein kinase C and extracellular calcium.
Topics: Base Sequence; Calcimycin; Calcitriol; Calcium; Cell Line; DNA Primers; Egtazic Acid; Enzyme Inhibitors; Extracellular Space; Gene Expression; Granzymes; Humans; Ionophores; Isoenzymes; Killer Cells, Natural; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Endopeptidases; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1999 |
Cholecystokinin activates PYK2/CAKbeta by a phospholipase C-dependent mechanism and its association with the mitogen-activated protein kinase signaling pathway in pancreatic acinar cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Biological Transport; Calcimycin; Calcium; Cell Adhesion Molecules; Cholecystokinin; Colchicine; Cytochalasin D; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; GRB2 Adaptor Protein; In Vitro Techniques; Indoles; Male; Maleimides; MAP Kinase Signaling System; Models, Biological; Pancreas; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases | 1999 |
Externalization of tropomyosin isoform 5 in colon epithelial cells.
Topics: Calcimycin; Cells, Cultured; Colon; Dimerization; Epithelial Cells; Extracellular Space; HT29 Cells; Humans; Intestinal Mucosa; Ionophores; Membrane Proteins; Protein Isoforms; Tetradecanoylphorbol Acetate; Tropomyosin | 1999 |
Adhesion of human mast cells to extracellular matrix provides a co-stimulatory signal for cytokine production.
Topics: Calcimycin; Cell Adhesion; Cell Line; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix Proteins; Fibronectins; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-6; Interleukin-8; Interleukins; Ionophores; Mast Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Vitronectin | 1999 |
Cytosolic phospholipase A2-mediated regulation of phospholipase D2 in leukocyte cell lines.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; COS Cells; Cytosol; Enzyme Activation; Enzyme Inhibitors; Humans; Isoenzymes; Leukemia L1210; Leukemia P388; Leukocytes; Lysophosphatidylcholines; Mice; Oligonucleotides, Antisense; Phospholipase D; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; U937 Cells | 1999 |
Rapid degradation of PrxI and PrxII induced by silica in Rat2 cells.
Topics: Animals; Antioxidants; Calcimycin; Cell Line; DNA-Binding Proteins; Humans; Hydrogen Peroxide; I-kappa B Proteins; Ionophores; NF-KappaB Inhibitor alpha; Oxidative Stress; Peroxidases; Peroxiredoxins; Rats; Reactive Oxygen Species; Silicon Dioxide; Silicosis; Tetradecanoylphorbol Acetate | 1999 |
Annexins VII and XI are present in a human macrophage-like cell line. Differential translocation on FcR-mediated phagocytosis.
Topics: Annexin A7; Annexins; Calcimycin; Calcium; Cell-Free System; Humans; Ionophores; Macrophages; Mitogens; Phagocytosis; Phagosomes; Proteins; Receptors, Fc; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Cyclic AMP inhibits the activity of c-Jun N-terminal kinase (JNKp46) but not JNKp55 and ERK2 in human helper T lymphocytes.
Topics: Antibodies; Bucladesine; Calcimycin; Cell Line; Cyclic AMP; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Molecular Weight; Myelin Basic Protein; Phosphorylation; Phosphoserine; Precipitin Tests; Proto-Oncogene Proteins c-jun; Recombinant Fusion Proteins; Signal Transduction; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate | 1999 |
T cell activation up-regulates the expression of the focal adhesion kinase Pyk2: opposing roles for the activation of protein kinase C and the increase in intracellular Ca2+.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; CD28 Antigens; Cell Adhesion Molecules; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Humans; Intracellular Fluid; Ionophores; Jurkat Cells; Lymphocyte Activation; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic; Up-Regulation | 1999 |
Effects of alpha-galactosylceramide (KRN7000), interleukin-12 and interleukin-7 on phenotype and cytokine profile of human Valpha24+ Vbeta11+ T cells.
Topics: Adult; Antineoplastic Agents; Calcimycin; Cells, Cultured; Clone Cells; Cytokines; Female; Flow Cytometry; Galactosylceramides; Granzymes; Humans; Interferon-gamma; Interleukin-12; Interleukin-4; Interleukin-7; Ionophores; Killer Cells, Natural; Lymphocyte Activation; Male; Serine Endopeptidases; Tetradecanoylphorbol Acetate; Th1 Cells | 1999 |
[Dependence of EHF EMF effects on the value of the static magnetic field].
Topics: Animals; Calcimycin; Electromagnetic Fields; Mice; Neutrophil Activation; Neutrophils; Protein Kinase C; Radiation Effects; Tetradecanoylphorbol Acetate | 1999 |
Trafficking and proteolytic release of epidermal growth factor receptor ligands are modulated by their membrane-anchoring domains.
Topics: Biological Transport; Calcimycin; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Heparin-binding EGF-like Growth Factor; Hydroxamic Acids; Intercellular Signaling Peptides and Proteins; Ligands; Metalloendopeptidases; Peptide Fragments; Protein Engineering; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2000 |
Free PKC catalytic subunits (PKM) phosphorylate tau via a pathway distinct from that utilized by intact PKC.
Topics: Autoradiography; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Calpain; Catalysis; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Densitometry; Enzyme Activators; Enzyme Inhibitors; Humans; Immunoblotting; Immunohistochemistry; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Protein Kinase C; tau Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1999 |
Proteolysis of synaptobrevin, syntaxin, and SNAP-25 in alveolar epithelial type II cells.
Topics: Animals; Antigens, Surface; Blotting, Western; Calcimycin; Calpain; Epithelial Cells; Fluorescent Antibody Technique; Glycoproteins; Ionophores; Membrane Proteins; Nerve Tissue Proteins; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Surfactants; R-SNARE Proteins; Rats; Secretory Rate; Synaptosomal-Associated Protein 25; Syntaxin 1; Tetradecanoylphorbol Acetate | 1999 |
A tumor necrosis factor decoy receptor homologue is up-regulated in the brook trout (Salvelinus fontinalis) ovary at the completion of ovulation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Calcimycin; Cloning, Molecular; DNA, Complementary; Female; GPI-Linked Proteins; In Situ Hybridization; Molecular Sequence Data; Ovary; Ovulation; Polymerase Chain Reaction; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 10c; RNA, Messenger; Tetradecanoylphorbol Acetate; Trout; Tumor Necrosis Factor Decoy Receptors; Up-Regulation | 2000 |
Down-regulation of the endoplasmic reticulum chaperone GRP78/BiP by vomitoxin (Deoxynivalenol).
Topics: Animals; Blotting, Western; Calcimycin; Carrier Proteins; DNA Fragmentation; DNA, Complementary; Down-Regulation; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Ionomycin; Ionophores; Mice; Molecular Chaperones; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thapsigargin; Thymoma; Trichothecenes | 2000 |
Gamma radiation and release of norepinephrine in the hippocampus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium Channel Agonists; Calcium Signaling; Gamma Rays; Hippocampus; Ionophores; Norepinephrine; Rats; Tetradecanoylphorbol Acetate | 1999 |
Induction and secretion of the chemokines interleukin-8 and monocyte chemotactic protein-1 in human immature leukemia cell lines.
Topics: Calcimycin; Carcinogens; Chemokine CCL2; Chemokines; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glucocorticoids; HL-60 Cells; Humans; Interleukin-8; Ionophores; Leukemia; Protein Biosynthesis; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Suppression of lymphocyte mitogenesis by tamoxifen: studies on protein kinase C, calmodulin and calcium.
Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Cell Division; Cells, Cultured; DNA; Estradiol; Female; Lymphocyte Activation; Lymphocytes; Male; Mitogens; Protein Kinase C; Rats; Rats, Inbred F344; Spleen; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
Transient translocation and activation of protein phosphatase 2A during mast cell secretion.
Topics: Animals; Antigens; beta-N-Acetylhexosaminidases; Calcimycin; Cell Line; Dinitrophenols; Enzyme Activation; Immunoglobulin E; Marine Toxins; Mast Cells; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Rats; Serum Albumin, Bovine; Signal Transduction; Tetradecanoylphorbol Acetate | 2000 |
Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Line; Cell Polarity; Cyclic AMP-Dependent Protein Kinases; Cyclohexanones; Cyclooxygenase Inhibitors; Dogs; Endocytosis; Enzyme Activation; Enzyme Inhibitors; Heterotrimeric GTP-Binding Proteins; Intercellular Signaling Peptides and Proteins; Ionomycin; Lipoprotein Lipase; Lipoxygenase Inhibitors; Organophosphonates; Peptides; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Protein Kinase C; Ricin; Signal Transduction; Tetradecanoylphorbol Acetate; Wasp Venoms | 2000 |
Impaired signal transduction in mitogen activated rat splenic lymphocytes during aging.
Topics: Aging; Animals; Calcimycin; Enzyme Activation; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Lymphocyte Activation; Lymphocytes; Male; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitogens; Phosphorylation; Proteins; Rats; Rats, Inbred F344; Signal Transduction; Spleen; Tetradecanoylphorbol Acetate; Transcription Factors; Tyrosine | 2000 |
Effects of ethanol, acetaldehyde, and acetic acid on histamine secretion in guinea pig lung mast cells.
Topics: Acetaldehyde; Acetates; Animals; Antigens; Calcimycin; Calcium; Central Nervous System Depressants; Ethanol; Female; Glucose; Guinea Pigs; Histamine Release; Lung; Male; Mast Cells; Phosphatidic Acids; Tetradecanoylphorbol Acetate | 2000 |
Effects of an inhibitor of myosin light chain kinase on amylase secretion from rat pancreatic acini.
Topics: Amylases; Androstadienes; Animals; Calcimycin; Calcium; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Male; Myosin-Light-Chain Kinase; Pancreas; Rats; Rats, Wistar; Signal Transduction; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Wortmannin | 2000 |
Nitric oxide mediated endothelium-dependent relaxation induced by glibenclamide in rat isolated aorta.
Topics: Animals; Aorta; Arginine; Calcimycin; Calcium Chloride; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Garlic extracts stimulate proliferation of rat lymphocytes in vitro by increasing IL-2 and IL-4 production.
Topics: Allium; Animals; Antibodies, Monoclonal; Calcimycin; Cell Division; Cytokines; In Vitro Techniques; Interleukin-2; Interleukin-4; Lymphocytes; Male; Microscopy, Fluorescence; Plant Extracts; Rats; Rats, Inbred Strains; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; Spleen; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Up-Regulation | 2000 |
C3 synthesis and CRs expression during differentiation of a murine stem cell line.
Topics: Animals; Calcimycin; Cell Differentiation; Cell Line; Complement C3; Cytochalasin D; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Receptors, Complement; Stem Cells; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases.
Topics: Amino Acid Sequence; Animals; Arachidonate 5-Lipoxygenase; Arsenites; Calcimycin; Cell Line; Cricetinae; Humans; Intracellular Signaling Peptides and Proteins; Kinetics; Mice; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sodium Compounds; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Necrosis Factor-alpha | 2000 |
Ca2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Calcimycin; Calcineurin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Heart; Ionomycin; Kinetics; Models, Cardiovascular; Myocardium; Myosin Heavy Chains; Promoter Regions, Genetic; Rats; Rats, Wistar; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 2000 |
Chloroquine: a multipotent inhibitor of human platelets in vitro.
Topics: Adult; Arachidonic Acid; Blood Platelets; Calcimycin; Chloroquine; Dose-Response Relationship, Drug; Epinephrine; Humans; Malondialdehyde; Middle Aged; Platelet Aggregation; Serotonin; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane B2; Time Factors; Tritium | 2000 |
Regulation of human PLD1 and PLD2 by calcium and protein kinase C.
Topics: Animals; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Baculoviridae; Calcimycin; Calcium; Cell Line; DNA, Recombinant; Dose-Response Relationship, Drug; Endotoxins; Enzyme Activation; Hemolysin Proteins; Humans; Membranes; Phospholipase D; Protein Kinase C; Tetradecanoylphorbol Acetate | 2000 |
Expression of soluble CD137 correlates with activation-induced cell death of lymphocytes.
Topics: Antigens, CD; Calcimycin; Cell Death; Cell Division; Flow Cytometry; Gene Expression Regulation; Humans; Kinetics; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Protein Isoforms; Receptors, Nerve Growth Factor; Receptors, Tumor Necrosis Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor Receptor Superfamily, Member 9 | 2000 |
Cytosolic phospholipase A2 is required for macrophage arachidonic acid release by agonists that Do and Do not mobilize calcium. Novel role of mitogen-activated protein kinase pathways in cytosolic phospholipase A2 regulation.
Topics: Animals; Anisomycin; Arachidonic Acid; Calcimycin; Calcium; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Ionophores; Macrophages; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NADPH Oxidases; Okadaic Acid; Phospholipase D; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Synthesis Inhibitors; Serine; Tetradecanoylphorbol Acetate; Time Factors; Zymosan | 2000 |
Involvement of different protein kinases and phospholipases A2 in phorbol ester (TPA)-induced arachidonic acid liberation in bovine platelets.
Topics: Animals; Arachidonic Acid; Blood Platelets; Calcimycin; Cattle; Cells, Cultured; Group IV Phospholipases A2; Phospholipases A; Phospholipases A2; Protein Kinase Inhibitors; Protein Kinases; Tetradecanoylphorbol Acetate | 2000 |
Phosphatase inhibitors and premature chromosome condensation in human peripheral lymphocytes at different cell-cycle phases.
Topics: Calcimycin; Cell Cycle; Chromosomes, Human; Enzyme Inhibitors; Humans; Ionophores; Lymphocytes; Marine Toxins; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate | 1999 |
Absence of CD40-CD40 ligand interactions in X-linked hyper-IgM syndrome does not affect differentiation of T helper cell subsets.
Topics: Adolescent; Adult; Calcimycin; Calcium; CD3 Complex; CD40 Antigens; CD40 Ligand; CD8-Positive T-Lymphocytes; Cell Differentiation; Child; Child, Preschool; Female; Humans; Hypergammaglobulinemia; Immunoglobulin M; Immunologic Memory; Infant; Ionophores; Lipopolysaccharide Receptors; Lipopolysaccharides; Lymphocyte Activation; Lymphokines; Male; Membrane Glycoproteins; Monocytes; Monokines; Syndrome; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells; X Chromosome | 2000 |
The effect of a Rho kinase inhibitor Y-27632 on superoxide production, aggregation and adhesion in human polymorphonuclear leukocytes.
Topics: Adult; Amides; Calcimycin; Calcium; Cell Adhesion; Cell Aggregation; Enzyme Inhibitors; Guanosine 5'-O-(3-Thiotriphosphate); Humans; In Vitro Techniques; Indicators and Reagents; Intracellular Signaling Peptides and Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; Superoxides; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Bioactive proteinase 3 on the cell surface of human neutrophils: quantification, catalytic activity, and susceptibility to inhibition.
Topics: Calcimycin; Catalysis; Cell Degranulation; Cell Membrane; Cytochalasin B; Enzyme Activation; Humans; Immunohistochemistry; Inflammation Mediators; Membrane Proteins; Molecular Weight; Myeloblastin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Osmolar Concentration; Protein Binding; Serine Endopeptidases; Serine Proteinase Inhibitors; Sodium Chloride; Tetradecanoylphorbol Acetate | 2000 |
The effects of calcium channel blockers on nuclear factor kappa B activation in the mesangium cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcimycin; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Carcinogens; Cells, Cultured; Dihydropyridines; Gene Expression; Genes, Reporter; Glomerular Mesangium; Humans; Ionophores; Luciferases; NF-kappa B; Nifedipine; Nitrophenols; Organophosphorus Compounds; Tetradecanoylphorbol Acetate; Verapamil | 2000 |
Up-regulation of nucleolin mRNA and protein in peripheral blood mononuclear cells by extracellular-regulated kinase.
Topics: 3' Untranslated Regions; Adenylyl Cyclases; Amyloid beta-Protein Precursor; Animals; Calcimycin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Gene Expression Regulation; Humans; In Vitro Techniques; Kinetics; Leukocytes, Mononuclear; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nuclear Proteins; Nucleolin; Phosphoproteins; Protein Biosynthesis; Protein Kinase C; Rabbits; Reticulocytes; RNA-Binding Proteins; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Type C Phospholipases | 2001 |
Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts.
Topics: Animals; Biological Clocks; Bucladesine; Calcimycin; Cell Cycle Proteins; Cell Line; Circadian Rhythm; Colforsin; Culture Media; Dimethyl Sulfoxide; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; Insulin; Nuclear Proteins; Okadaic Acid; Period Circadian Proteins; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic | 2000 |
Specific induction of RGS16 (regulator of G-protein signalling 16) mRNA by protein kinase C in CEM leukaemia cells is mediated via tumour necrosis factor alpha in a calcium-sensitive manner.
Topics: Androstadienes; Bucladesine; Calcimycin; Calcineurin; Calcium; Calcium Signaling; Cyclosporine; DNA-Binding Proteins; Egtazic Acid; Enzyme Activation; Humans; Kinetics; Mitogen-Activated Protein Kinases; NFATC Transcription Factors; Nuclear Proteins; Protein Kinase C; Proteins; RGS Proteins; RNA, Messenger; Tacrolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation; Wortmannin | 2000 |
Ethanol inhibits IgE-induced degranulation and cytokine production in cultured mouse and human mast cells.
Topics: Animals; beta-N-Acetylhexosaminidases; Bone Marrow Cells; Calcimycin; Cell Degranulation; Cell Division; Cells, Cultured; Cytokines; Cytoplasmic Granules; Ethanol; Humans; Immunoglobulin E; Interleukin-8; Kinetics; Mast Cells; Mice; Mice, Inbred BALB C; Recombinant Proteins; Stem Cell Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2000 |
Activation of human neutrophils with chemotactic peptide, opsonized zymosan and the calcium ionophore A23187, but not with a phorbol ester, is accompanied by efflux and store-operated influx of calcium.
Topics: Calcimycin; Calcium; Fluorescent Dyes; Fura-2; Humans; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan | 2000 |
Human dendritic cells are a physiological source of the chemotactic arachidonic acid metabolite 5-oxo-eicosatetraenoic acid.
Topics: Arachidonic Acids; Calcimycin; Chemotactic Factors; Chromatography, High Pressure Liquid; Dendritic Cells; Humans; Hydroxyeicosatetraenoic Acids; Ionophores; Neutrophils; Tetradecanoylphorbol Acetate | 2000 |
Urea signaling to ERK phosphorylation in renal medullary cells requires extracellular calcium but not calcium entry.
Topics: Animals; Calcimycin; Calcium; Cell Culture Techniques; Cell Line; Enzyme Activation; Epidermal Growth Factor; Ionomycin; Kidney Medulla; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Urea | 2001 |
Protein kinase C modulates Ca2+-activated K+ channels in cultured rat mesenteric artery smooth muscle cells.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Cells, Cultured; Electric Conductivity; Enzyme Activation; Ionophores; Kinetics; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Potassium Channels; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2000 |
Effects of cellular mediator agonists on cortisol and steroid acute regulatory (StAR) protein in bovine zona fasciculata (ZF) cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Calcium Channel Agonists; Cattle; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Hydrocortisone; Ionophores; Phosphoproteins; Tetradecanoylphorbol Acetate; Zona Fasciculata | 2000 |
The stimulation of MAP kinase by 1,25(OH)(2)-vitamin D(3) in skeletal muscle cells is mediated by protein kinase C and calcium.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcitriol; Calcium; Calmodulin; Chick Embryo; Egtazic Acid; Enzyme Activation; Fluphenazine; Indoles; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Naphthalenes; Neomycin; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases; Verapamil | 2001 |
Characterization of adenylyl cyclases in cultured human granulosa cells.
Topics: Adenylyl Cyclases; Calcimycin; Calcium; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Female; Granulosa Cells; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Isoenzymes; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 2001 |
3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors block calcium-dependent tyrosine kinase Pyk2 activation by angiotensin II in vascular endothelial cells. involvement of geranylgeranylation of small G protein Rap1.
Topics: Angiotensin II; Animals; Calcimycin; Calcium; Calmodulin; Cell Membrane; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Focal Adhesion Kinase 2; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Prenylation; Protein-Tyrosine Kinases; Pulmonary Veins; rap1 GTP-Binding Proteins; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Simvastatin; Tetradecanoylphorbol Acetate | 2001 |
Contrasting effect of interleukin-4 on the expression of cytosolic phospholipase A2, 5-lipoxygenase and 5-lipoxygenase-activating protein in peritoneal macrophages from control and ovalbumin-sensitized rats.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Carrier Proteins; Cholesterol Esters; Cytosol; Gene Expression Regulation; Interleukin-4; Macrophages, Peritoneal; Male; Membrane Proteins; Ovalbumin; Phospholipases A; Phospholipases A2; Phospholipids; Rats; Tetradecanoylphorbol Acetate | 2001 |
NID67, a small putative membrane protein, is preferentially induced by NGF in PC12 pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Base Sequence; Calcimycin; Calcium; Cell Differentiation; Chromosomes, Human, Pair 5; Colforsin; Culture Media, Serum-Free; DNA, Complementary; DNA, Neoplasm; Epidermal Growth Factor; Female; Fibroblast Growth Factors; Gene Expression Regulation, Neoplastic; Humans; Ion Channels; Ionophores; Membrane Proteins; Mice; Molecular Sequence Data; Myocardium; Neoplasm Proteins; Nerve Growth Factor; Nerve Tissue Proteins; Open Reading Frames; Organ Specificity; Ovary; PC12 Cells; Pheochromocytoma; Polymerase Chain Reaction; Potassium Chloride; Protein Structure, Tertiary; Rats; Second Messenger Systems; Sequence Alignment; Sequence Homology, Nucleic Acid; Tetradecanoylphorbol Acetate | 2001 |
Phorbol ester up-regulates capacities for nuclear translocation and phosphorylation of 5-lipoxygenase in Mono Mac 6 cells and human polymorphonuclear leukocytes.
Topics: Active Transport, Cell Nucleus; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Calcium; Calcium Signaling; Cell Line; Cell Nucleus; Enzyme Inhibitors; Humans; Ionophores; Leukotrienes; Membrane Lipids; Monocytes; Naphthalenes; Neutrophils; Phospholipases A; Phospholipids; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 2001 |
Key role of PKC and Ca2+ in EGF protection of microtubules and intestinal barrier against oxidants.
Topics: Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cell Membrane Permeability; Cytosol; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Hydrogen Peroxide; Hypochlorous Acid; Indoles; Intestinal Mucosa; Isoenzymes; Maleimides; Microtubules; Models, Biological; Oxidants; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Platelet CD40 ligand (CD40L)--subcellular localization, regulation of expression, and inhibition by clopidogrel.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Antigens, CD; Blood Platelets; Calcimycin; Calcium; CD40 Ligand; Cells, Cultured; Clopidogrel; Collagen; Cytoplasmic Granules; Cytoskeleton; Gene Expression Regulation; Humans; Ionophores; Male; P-Selectin; Peptide Fragments; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tetraspanin 30; Thrombin; Ticlopidine | 2001 |
Up-regulation of cyclooxygenase-1 in neuroblastoma cell lines by retinoic acid and corticosteroids.
Topics: Adrenal Cortex Hormones; Aldosterone; Animals; Benzimidazoles; Bucladesine; Calcimycin; Cell Differentiation; Cycloheximide; Cyclooxygenase 1; Cyclooxygenase 2; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dexamethasone; Dinoprostone; Drug Synergism; Enzyme Induction; Estradiol; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glioma; Hybrid Cells; Hydrocortisone; Ionophores; Isoenzymes; Luciferases; Membrane Proteins; Mice; Mifepristone; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Synthesis Inhibitors; Receptors, Glucocorticoid; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transfection; Tretinoin; Tumor Cells, Cultured | 2001 |
ZAP-70 and SLP-76 regulate protein kinase C-theta and NF-kappa B activation in response to engagement of CD3 and CD28.
Topics: Adaptor Proteins, Signal Transducing; Calcimycin; CD28 Antigens; CD3 Complex; Cell Cycle Proteins; DNA-Binding Proteins; Enzyme Activation; Humans; I-kappa B Proteins; Ionophores; Isoenzymes; Jurkat Cells; Kinetics; Lymphocyte Activation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphoproteins; Protein Kinase C; Protein Kinase C-theta; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine; ZAP-70 Protein-Tyrosine Kinase | 2001 |
Generation of reactive oxygen species by equine spermatozoa.
Topics: Animals; Calcimycin; Catalase; Centrifugation, Density Gradient; Cryopreservation; Horses; Hydrogen Peroxide; Ionophores; Male; Microscopy, Interference; N-Formylmethionine Leucyl-Phenylalanine; NADP; Reactive Oxygen Species; Semen Preservation; Spermatozoa; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Roles of protein kinase C and Ca2+-dependent signaling in angiotensin II-induced adrenomedullin production in rat cardiac myocytes.
Topics: Adrenomedullin; Angiotensin II; Animals; Biological Transport; Calcimycin; Calcium; Calcium Signaling; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Intracellular Membranes; Ionophores; Isoenzymes; Myocardium; Peptides; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2001 |
Calcium-dependent interleukin-8 gene expression in T84 human colonic epithelial cells.
Topics: Adenocarcinoma; Calcimycin; Calcineurin; Calcium; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression; Humans; Interleukin-8; Ionophores; Kinetics; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription, Genetic; Tumor Cells, Cultured | 2001 |
Extracellular-regulated kinase controls beta-amyloid precursor protein mRNA decay.
Topics: Amyloid beta-Protein Precursor; Butadienes; Calcimycin; Calcium; Carcinogens; Enzyme Inhibitors; Gene Expression; Humans; Ionomycin; Ionophores; Leukocytes, Mononuclear; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitriles; Protein Kinase C; RNA Processing, Post-Transcriptional; RNA, Messenger; Tetradecanoylphorbol Acetate | 2001 |
Human blood platelets, PMN leukocytes and their interactions in vitro. Responses to selective and non-selective stimuli.
Topics: Adult; Blood Platelets; Calcimycin; Cell Communication; Humans; In Vitro Techniques; Luminescent Measurements; Luminol; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombin | 2000 |
Increased expression of cytosolic phospholipase A2, 5-lipoxygenase and 5-lipoxygenase-activating protein in rat peritoneal macrophages during ovalbumin-induced sensitization.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Carrier Proteins; Cells, Cultured; Cytosol; Injections, Subcutaneous; Interleukin-4; Macrophages, Peritoneal; Male; Membrane Proteins; Ovalbumin; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred BN; Tetradecanoylphorbol Acetate | 2001 |
The ascomycin macrolactam pimecrolimus (Elidel, SDZ ASM 981) is a potent inhibitor of mediator release from human dermal mast cells and peripheral blood basophils.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Basophils; Calcimycin; Dose-Response Relationship, Drug; Histamine Release; Humans; Hypersensitivity; Immunoglobulin E; Inflammation Mediators; Mast Cells; Skin; Tacrolimus; Tetradecanoylphorbol Acetate | 2001 |
Effects of second messengers on gap junctional intercellular communication of ovine luteal cells throughout the estrous cycle.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Western; Bucladesine; Calcimycin; Calcium; Cells, Cultured; Chelating Agents; Culture Media, Conditioned; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Estrous Cycle; Female; Fluorescent Antibody Technique; Gap Junctions; Immunohistochemistry; Ionophores; Luteal Cells; Progesterone; Protein Kinase C; Second Messenger Systems; Sheep; Tetradecanoylphorbol Acetate; Thionucleotides | 2001 |
Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia.
Topics: Adult; Blood Glucose; Calcimycin; Cells, Cultured; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hyperglycemia; Leukotriene B4; Lysosomes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
Identification of specific gravity sensitive signal transduction pathways in human A431 carcinoma cells.
Topics: Calcimycin; Carcinogens; Carcinoma, Squamous Cell; Colforsin; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Gravitation; Humans; Ionophores; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rotation; Signal Transduction; Space Flight; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Weightlessness; Weightlessness Simulation | 1992 |
Altered gravity conditions affect early EGF-induced signal transduction in human epidermal A431 cells.
Topics: Calcimycin; Centrifugation; Colforsin; Epidermal Growth Factor; ErbB Receptors; Gene Expression; Genes, fos; Gravitation; Gravity, Altered; Humans; Protein Kinase C; Receptor Aggregation; Rotation; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
[Production and secretion of interleukin 6 from stimulated peritoneal macrophages of the mouse].
Topics: Animals; Calcimycin; Calcium Channel Agonists; Cells, Cultured; Female; Interleukin-6; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Tetradecanoylphorbol Acetate | 1997 |
Effect of Leishmania donovani lipophosphoglycan on ornithine decarboxylase activity in macrophages.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anti-Bacterial Agents; Bucladesine; Calcimycin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glycosphingolipids; Leishmania donovani; Leishmaniasis, Visceral; Lipopolysaccharides; Macrophages; Mice; Okadaic Acid; Ornithine Decarboxylase; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Regulation of the very late antigen-4-mediated adhesive activity of normal and nonreleaser basophils: roles for Src, Syk, and phosphatidylinositol 3-kinase.
Topics: Acridines; Androstadienes; Animals; Basophils; Calcimycin; Calcium; Cell Adhesion; CHO Cells; Cricetinae; Cricetulus; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Humans; Immunologic Capping; Integrin alpha4beta1; Integrins; Intracellular Signaling Peptides and Proteins; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Receptors, IgE; Receptors, Lymphocyte Homing; Recombinant Fusion Proteins; Signal Transduction; src-Family Kinases; Syk Kinase; Tetradecanoylphorbol Acetate; Transfection; Up-Regulation; Vascular Cell Adhesion Molecule-1; Wortmannin | 2001 |
Effects of liposomes of different phospholipid composition on the induction of respiratory burst in human blood monocytes and alveolar macrophages.
Topics: Arachidonic Acid; Calcimycin; Diglycerides; Fatty Acids; Humans; Ionophores; Liposomes; Macrophage Activation; Macrophages, Alveolar; Monocytes; NADPH Oxidases; Phosphatidylcholines; Phospholipids; Respiratory Burst; Tetradecanoylphorbol Acetate | 2001 |
Interferon-gamma secretion of peripheral blood CD8+ T lymphocytes in patients with bronchial asthma: in vitro stimulus determines cytokine production.
Topics: Adult; Animals; Asthma; Calcimycin; Case-Control Studies; CD8-Positive T-Lymphocytes; Cytokines; Female; Humans; In Vitro Techniques; Interferon-gamma; Ionophores; Leukocytes, Mononuclear; Male; Middle Aged; Muromonab-CD3; Tetradecanoylphorbol Acetate | 2001 |
Identification of signal transduction pathways and promoter sequences that mediate parathyroid hormone 1-38 inhibition of osteoprotegerin gene expression.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcimycin; Colforsin; Gene Expression; Glycoproteins; Osteoblasts; Osteoprotegerin; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Peptide Fragments; Promoter Regions, Genetic; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 2001 |
[Luminescence analysis of respiratory burst in neutrophils using microtiter plates].
Topics: Calcimycin; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
Evidence for the involvement of the NADPH oxidase enzyme complex in the optimal accumulation of Platelet-activating factor in the human cell line PLB-985.
Topics: Calcimycin; Calcium; Cell Line; Gas Chromatography-Mass Spectrometry; Glycerylphosphorylcholine; Humans; Ionophores; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphatidylcholines; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Taurine attenuates the induction of immediate-early gene expression by PDGF-BB.
Topics: 3T3 Cells; Animals; Becaplermin; Calcimycin; Cell Line; Gene Expression; Genes, fos; Genes, Immediate-Early; Ionophores; Mice; Mice, Inbred BALB C; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Proto-Oncogene Proteins c-sis; Rats; Taurine; Tetradecanoylphorbol Acetate; Transcription Factors | 2000 |
Estrogen regulates cytokine release in human mast cells.
Topics: Calcimycin; Cell Line; Culture Media; Cytokines; Estradiol; Humans; Interleukin-6; Ionophores; Mast Cells; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Signalling components underlying platelet aggregation to a Ca2+ ionophore and a phorbol ester.
Topics: Adenosine Diphosphate; Androstadienes; Calcimycin; Calcium Signaling; Chromones; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Humans; Indoles; Ionophores; Morpholines; Phosphatidylinositol 3-Kinases; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboxanes; Type C Phospholipases; Wortmannin | 2001 |
Distinction between IL-13+ and IFN-gamma+ natural killer cells and regulation of their pool size by IL-4.
Topics: Adult; Calcimycin; Cell Division; Humans; In Vitro Techniques; Infant, Newborn; Interferon-gamma; Interleukin-13; Interleukin-4; Ionophores; Killer Cells, Natural; Lymphocyte Subsets; Phenotype; Tetradecanoylphorbol Acetate | 2002 |
Oxytocin stimulation of RGS2 mRNA expression in cultured human myometrial cells.
Topics: Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Drug Synergism; Egtazic Acid; Enzyme Activation; Female; Gene Expression; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Humans; Inositol Phosphates; Ionophores; Myometrium; Oxytocin; Pregnancy; Protein Kinase C; RGS Proteins; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 2002 |
Protein phosphatases 1 and 2A transiently associate with myosin during the peak rate of secretion from mast cells.
Topics: Actins; Animals; Antineoplastic Agents; Calcimycin; Cell Line; Cell Membrane; Cytoskeletal Proteins; Cytoskeleton; Depsipeptides; Enzyme Inhibitors; Exocytosis; Immunoglobulin E; Ionophores; Mast Cells; Myosins; Okadaic Acid; Peptide Mapping; Peptides, Cyclic; Phosphoprotein Phosphatases; Rats; Tetradecanoylphorbol Acetate | 2002 |
Production of recombinant goldfish prolactin and its applications in radioreceptor binding assay and radioimmunoassay.
Topics: Animals; Calcimycin; Cells, Cultured; Escherichia coli; Goldfish; Ionophores; Kinetics; Prolactin; Radioimmunoassay; Radioligand Assay; Recombinant Proteins; Reproducibility of Results; Tetradecanoylphorbol Acetate | 2002 |
Haptoglobin interacts with the human mast cell line HMC-1 and inhibits its spontaneous proliferation.
Topics: Antigens, CD; Calcimycin; Calcium; Cell Division; Cell Line; Haptoglobins; Humans; Hyaluronan Receptors; Leukosialin; Mast Cells; Sialoglycoproteins; Tetradecanoylphorbol Acetate | 2002 |
Anti-inflammatory triterpenes from Pistacia terebinthus galls.
Topics: Animals; Anti-Inflammatory Agents; Calcimycin; Cyproheptadine; Dexamethasone; Dose-Response Relationship, Drug; Hindlimb; Inflammation; Ionophores; Leukotriene B4; Magnetic Resonance Spectroscopy; Mice; Neutrophils; Phospholipases A; Phospholipases A2; Pistacia; Plant Extracts; Tetradecanoylphorbol Acetate; Triterpenes | 2002 |
Evaluation of cell-surface IgE receptors on the canine mastocytoma cell line C2 maintained in continuous culture.
Topics: Animals; Antibodies, Bacterial; Antigens, Bacterial; Ascaris suum; beta-N-Acetylhexosaminidases; Calcimycin; Dogs; Flow Cytometry; Ionophores; Mast-Cell Sarcoma; Receptors, IgE; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Mechanism of angiotensin II-induced phospholipase D activation in bovine adrenal glomerulosa cells.
Topics: 1-Butanol; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aldosterone; Angiotensin II; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Carbazoles; Cattle; Cells, Cultured; Diglycerides; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Indoles; Ionomycin; Nitrendipine; Phospholipase D; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Zona Glomerulosa | 2002 |
Protein kinase C-associated kinase (PKK) mediates Bcl10-independent NF-kappa B activation induced by phorbol ester.
Topics: Adaptor Proteins, Signal Transducing; Animals; B-Cell CLL-Lymphoma 10 Protein; Binding Sites; Calcimycin; Cell Line; Fibroblasts; Gene Deletion; Humans; Mice; Neoplasm Proteins; NF-kappa B; Plasmids; Protein Kinases; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2002 |
Inhibition of arachidonic acid release from human peripheral mononuclear cells by heat shock treatment and geldanamycin.
Topics: Arachidonic Acid; Benzoquinones; Calcimycin; Cells, Cultured; Enzyme Inhibitors; Heat-Shock Response; Hot Temperature; Humans; Ionophores; Lactams, Macrocyclic; Leukocytes, Mononuclear; Quinones; Tetradecanoylphorbol Acetate | 2002 |
Identification of second messengers that induce expression of functional gap junctions in microglia cultured from newborn rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Calcimycin; Calcium; Calcium Signaling; Cells, Cultured; Central Nervous System; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Fluorescent Dyes; Gap Junctions; GAP-43 Protein; Gliosis; Ionophores; Isoquinolines; Microglia; Protein Kinase C; Rats; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Up-Regulation | 2002 |
Studies on glycogen autophagy: effects of phorbol myristate acetate, ionophore A23187, or phentolamine.
Topics: Animals; Animals, Newborn; Autophagy; Calcimycin; Cells, Cultured; Cyclic AMP; Glycogen; Hepatocytes; Ionophores; Liver; Lysosomes; Microscopy, Electron; Phentolamine; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2002 |
Antigen-independent induction of histamine synthesis by immunoglobulin E in mouse bone marrow-derived mast cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antigens; Calcimycin; Calcium Signaling; Enzyme Inhibitors; Estrenes; Female; Histamine; Histidine Decarboxylase; Immunoglobulin E; In Vitro Techniques; Interleukin-3; Mast Cells; Mice; Mice, Inbred BALB C; Protein Kinase C; Pyrrolidinones; Receptors, IgE; RNA, Messenger; src-Family Kinases; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2002 |
Effects of rhinovirus infection on histamine and cytokine production by cell lines from human mast cells and basophils.
Topics: Basophils; Calcimycin; Calcium; Cell Line; Common Cold; Cytokines; DNA; Histamine Release; Humans; Intercellular Adhesion Molecule-1; Mast Cells; NF-kappa B; RNA, Viral; Tetradecanoylphorbol Acetate | 2002 |
Regulatory effects of eotaxin, eotaxin-2, and eotaxin-3 on eosinophil degranulation and superoxide anion generation.
Topics: Calcimycin; Chemokine CCL11; Chemokine CCL24; Chemokine CCL26; Chemokines, CC; Cytoplasmic Granules; Eosinophil Peroxidase; Eosinophils; HL-60 Cells; Humans; Interleukin-5; Ionophores; Peroxidases; Receptors, CCR3; Receptors, Chemokine; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate | 2002 |
Activation of channel catfish (Ictalurus punctatus) T cells involves NFAT-like transcription factors.
Topics: Animals; Blotting, Western; Calcimycin; Concanavalin A; Cyclosporine; DNA-Binding Proteins; Ictaluridae; Immunosuppressive Agents; Lipopolysaccharides; Lymphocyte Activation; NFATC Transcription Factors; Nuclear Proteins; Phosphoric Monoester Hydrolases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine; Transcription Factors | 2002 |
Phorbol ester stimulates a protein kinase C-mediated agatoxin-TK-sensitive calcium permeability pathway in human red blood cells.
Topics: Adult; Agatoxins; Alkaloids; Benzophenanthridines; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Signaling; Cell Size; Diglycerides; Dimethyl Sulfoxide; Enzyme Inhibitors; Erythrocytes; Humans; Ion Transport; Ionophores; Marine Toxins; Okadaic Acid; Osmotic Fragility; Oxazoles; Phenanthridines; Phosphoprotein Phosphatases; Protein Kinase C; Spider Venoms; Staurosporine; Tetradecanoylphorbol Acetate | 2002 |
Multiple cis-acting elements regulate the expression of the early T cell activation antigen CD69.
Topics: Activating Transcription Factor 3; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; DNA-Binding Proteins; Early Growth Response Protein 1; Early Growth Response Protein 3; Gene Expression Regulation; Humans; Immediate-Early Proteins; Jurkat Cells; Lectins, C-Type; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic | 2002 |
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and inflammatory stimuli up-regulate secretion of the soluble GM-CSF receptor in human monocytes: evidence for ectodomain shedding of the cell surface GM-CSF receptor alpha subunit.
Topics: Alternative Splicing; Animals; Calcimycin; Cell Membrane; Cells, Cultured; Cricetinae; Endopeptidases; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrolysis; Inflammation Mediators; Lipopolysaccharides; Lymphocytes; Mice; Monocytes; Protein Structure, Tertiary; Protein Subunits; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Solubility; Tetradecanoylphorbol Acetate; Up-Regulation | 2002 |
Chlorpromazine inhibits the glucocorticoid receptor-mediated gene transcription in a calcium-dependent manner.
Topics: Animals; Antipsychotic Agents; Calcimycin; Calcium; Calcium Channel Blockers; Cell Line; Cell Line, Transformed; Chloramphenicol O-Acetyltransferase; Chlorpromazine; Clozapine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Estrenes; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Haloperidol; Histamine; Histamine H1 Antagonists; Ionophores; Mammary Tumor Virus, Mouse; Mice; Nifedipine; Phorbol Esters; Phosphodiesterase Inhibitors; Protein Kinase C; Protein Kinase C-alpha; Pyrilamine; Pyrrolidinones; Raclopride; Receptors, Glucocorticoid; Remoxipride; Sulfonamides; Sulpiride; Tetradecanoylphorbol Acetate; Thionucleotides; Transcription, Genetic; Type C Phospholipases | 2002 |
Modulation of endothelial permeability by 1-O-alkylglycerols.
Topics: Albumins; Animals; Aorta; Calcimycin; Cell Membrane Permeability; Cells, Cultured; Coloring Agents; Diglycerides; Endothelium, Vascular; Glycerol; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2002 |
Recruitment of murine neutrophils in vivo through endogenous sialidase activity.
Topics: Animals; Blotting, Western; Bronchi; Calcimycin; Clostridium perfringens; Humans; Immunoglobulin G; Interleukin-8; Mice; Models, Animal; N-Formylmethionine Leucyl-Phenylalanine; Neuraminidase; Neutrophils; Rabbits; Tetradecanoylphorbol Acetate | 2003 |
Products of phosphoinositide specific phospholipase C can trigger dephosphorylation of cofilin in chemoattractant stimulated neutrophils.
Topics: Actin Depolymerizing Factors; Animals; Calcimycin; Calmodulin; Carcinogens; Chemotactic Factors; Enzyme Inhibitors; Guinea Pigs; Immunoblotting; Ionophores; Marine Toxins; Microfilament Proteins; Neutrophils; Oxazoles; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Phosphorylation; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 2003 |
Antiplatelet activity of carvedilol in comparison to propranolol.
Topics: Adenosine Diphosphate; Calcimycin; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; In Vitro Techniques; Platelet Aggregation; Platelet Aggregation Inhibitors; Propanolamines; Propranolol; Reference Values; Tetradecanoylphorbol Acetate | 2002 |
Mast cells produce interleukin-25 upon Fc epsilon RI-mediated activation.
Topics: Animals; Calcimycin; Calcineurin; Gene Expression Regulation; Immunoglobulin E; Interleukin-17; Interleukins; Mast Cells; Mice; Receptors, IgE; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Th2 Cells | 2003 |
Rapid generation of antigen-presenting cells from leukaemic blasts in acute myeloid leukaemia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antigen-Presenting Cells; Antigens, CD; Antigens, Neoplasm; Bone Marrow Cells; Calcimycin; Calcium; Cancer Vaccines; Cell Culture Techniques; Cryopreservation; Cytotoxicity, Immunologic; Feasibility Studies; Female; HLA-DR Antigens; Humans; Interleukin-4; Ionophores; Leukemia, Myeloid; Lymphocyte Culture Test, Mixed; Male; Middle Aged; Neoplastic Cells, Circulating; Neoplastic Stem Cells; Reproducibility of Results; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Time Factors; Tissue Preservation; Tumor Cells, Cultured; Vaccination | 2003 |
Effect of H1-antagonist Dithiaden on human PMN-leukocyte aggregation and chemiluminescence is stimulus-dependent.
Topics: Benzothiepins; Calcimycin; Cell Aggregation; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists; Humans; In Vitro Techniques; Ionophores; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Zymosan | 2002 |
Interferon-gamma stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2. A potentially novel pathway for interferon-gamma-mediated inhibition of gene transcription.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Apigenin; Blotting, Western; Calcimycin; Calcium; Casein Kinase II; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Genetic Vectors; Imidazoles; Indoles; Interferon-gamma; Macrophages; Maleimides; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transcription, Genetic; Transcriptional Activation; Tyrphostins | 2003 |
Tyrosine phosphorylation of a novel 100-kDa protein coupled to CD28 in resting human T cells is enhanced by a signal through TCR/CD3 complex.
Topics: Calcimycin; CD28 Antigens; Enzyme Inhibitors; Humans; Immunoblotting; Jurkat Cells; Lymphocyte Activation; Naphthalenes; Phosphoproteins; Phosphorylation; Precipitin Tests; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 2003 |
Calpain is involved in the HIV replication from the latently infected OM10.1 cells.
Topics: Acetylcysteine; Binding Sites; Calcimycin; Calcium Signaling; Calcium-Binding Proteins; Calpain; Cell Line; Glycoproteins; HIV-1; Humans; I-kappa B Proteins; In Vitro Techniques; Ionophores; Leucine; NF-kappa B; NF-KappaB Inhibitor alpha; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Virus Replication | 2003 |
Effect of Phlomis umbrosa root on mast cell-dependent immediate-type allergic reactions by anal therapy.
Topics: Administration, Rectal; Animals; Calcimycin; Cyclic AMP; Dinitrobenzenes; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Histamine Release; Hypersensitivity, Immediate; Immunoglobulin E; Interleukin-6; Mast Cells; Mice; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Peritoneum; Phlomis; Plant Roots; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2003 |
Atypical mechanisms regulate the PMA-induced expression of IFN-gamma in a porcine trophectoderm cell line.
Topics: Animals; Calcimycin; Cell Polarity; Cyclosporine; Dose-Response Relationship, Immunologic; Electric Impedance; Female; Gene Expression Regulation, Developmental; Immunosuppressive Agents; Interferon-gamma; Ionophores; Kinetics; Pregnancy; Swine; Tetradecanoylphorbol Acetate; Trophoblasts | 2003 |
Mannheimia haemolytica leukotoxin-induced increase in leukotriene B4 production by bovine neutrophils is mediated by a sustained and excessive increase in intracellular calcium concentration.
Topics: Animals; Calcimycin; Calcium; Calcium Signaling; Carcinogens; Cattle; Exotoxins; Ionophores; Leukotriene B4; Mannheimia haemolytica; Neutrophils; Pasteurellosis, Pneumonic; Tetradecanoylphorbol Acetate | 2003 |
Inhibition of cytokine gene transcription by the human recombinant histamine-releasing factor in human T lymphocytes.
Topics: Apoptosis; Biomarkers, Tumor; Calcimycin; CD28 Antigens; Cell Division; Cell Separation; Cytokines; Dose-Response Relationship, Immunologic; Down-Regulation; Drug Synergism; Gene Expression Regulation; Histamine Release; Humans; Interleukin-13; Interleukin-2; Interleukin-4; Jurkat Cells; Promoter Regions, Genetic; Receptors, Antigen, T-Cell; Recombinant Fusion Proteins; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Tumor Protein, Translationally-Controlled 1 | 2003 |
Effects of a caffeine-free Cola nitida nuts extract on elastase/alpha-1-proteinase inhibitor balance.
Topics: alpha 1-Antitrypsin; Caffeine; Calcimycin; Cell Survival; Cola; Enzyme Activators; Free Radical Scavengers; Humans; Hydrogen Peroxide; In Vitro Techniques; Ionophores; Leukocyte Elastase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nuts; Plant Extracts; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2003 |
Cholesterol depletion inhibits store-operated calcium currents and exocytotic membrane fusion in RBL-2H3 cells.
Topics: Animals; Antigens; beta-Cyclodextrins; Calcimycin; Calcium; Calcium Signaling; Cell Degranulation; Cell Line, Tumor; Cholesterol; Cyclodextrins; Down-Regulation; Exocytosis; Membrane Fusion; Membrane Microdomains; Protein Transport; Rats; src-Family Kinases; Tetradecanoylphorbol Acetate; Thapsigargin; Up-Regulation | 2003 |
Exocytosis of a complement component C3-like protein by tunicate hemocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Calcimycin; Carrageenan; Cell Survival; Cholera Toxin; Colchicine; Colforsin; Complement C3; Cytochalasin D; Cytoplasmic Vesicles; Enzyme-Linked Immunosorbent Assay; Exocytosis; Hemocytes; Immunohistochemistry; Kinetics; Lipopolysaccharides; Mannans; Microscopy, Electron; Phenanthridines; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Urochordata | 2004 |
Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils.
Topics: Animals; Arachidonic Acid; Calcimycin; Dietary Fats, Unsaturated; Dinoprostone; Eicosanoids; Fatty Acids; Fatty Acids, Essential; Fish Oils; gamma-Linolenic Acid; Glucuronidase; Glycogen; Hydrogen Peroxide; Inflammation; Linoleic Acid; Linoleic Acids; Lysosomes; Male; Muramidase; Neutrophils; Oenothera biennis; Oleic Acid; Olive Oil; Peritoneum; Peroxidase; Plant Oils; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 2004 |
Activation of integrin alpha IIb beta 3 in the glycoprotein Ib-high population of a megakaryocytic cell line, CMK, by inside-out signaling.
Topics: Alprostadil; Androstadienes; Calcimycin; Cell Line; Cytochalasin D; Humans; Ionophores; Isoenzymes; Megakaryocytes; Platelet Glycoprotein GPIb-IX Complex; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Ribavirin; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin | 2004 |
Altered AP-1 (activating protein-1) activity and c-jun activation in T cells exposed to the amide class herbicide 3,4-dichloropropionanilide (DCPA).
Topics: Anilides; Calcimycin; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Herbicides; Humans; Interleukin-2; Jurkat Cells; Phosphorylation; Proto-Oncogene Proteins c-jun; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription Factors | 2004 |
Calcium signaling pathway involving calcineurin regulates interleukin-8 gene expression through activation of NF-kappaB in human osteoblast-like cells.
Topics: Antineoplastic Agents; Calcimycin; Calcineurin; Calcium Signaling; Cell Line; Cyclosporine; Gene Expression Regulation; Humans; Immunosuppressive Agents; Interleukin-8; Ionophores; NF-kappa B; Osteoblasts; Promoter Regions, Genetic; Tacrolimus; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2004 |
Effects of intracellular calcium on cell survival and the MAPK pathway in a human hormone-dependent leukemia cell line (TF-1).
Topics: Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Division; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Humans; Indoles; Ionomycin; Leukemia; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Tetradecanoylphorbol Acetate | 2003 |
Local interaction of prostaglandin F 2alpha with endothelin-1 and tumor necrosis factor-alpha on the release of progesterone and oxytocin in ovine corpora lutea in vivo: a possible implication for a luteolytic cascade.
Topics: Animals; Calcimycin; Corpus Luteum; Dinoprost; Endothelin-1; Female; Ionophores; Luteolysis; Microdialysis; Oxytocin; Progesterone; Sheep; Superovulation; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2004 |
In vivo and in vitro anti-inflammatory activity of Mangifera indica L. extract (VIMANG).
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calcimycin; Cuba; Dexamethasone; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Ear, External; Edema; Eicosanoids; Indomethacin; Interferon-gamma; Leukotriene B4; Lipopolysaccharides; Macrophages; Male; Mangifera; Mice; Oleanolic Acid; Peroxidase; Phospholipases A; Phytotherapy; Plant Bark; Plant Extracts; Plant Stems; Plants, Medicinal; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Water; Xanthones | 2004 |
Inhibition of mast cell-dependent allergy reaction by extract of black cohosh (Cimicifuga racemosa).
Topics: Animals; Base Sequence; Calcimycin; Cell Line; Cimicifuga; Histamine Release; Humans; In Vitro Techniques; Interleukin-4; Interleukin-5; Male; Mast Cells; Mice; Mice, Inbred BALB C; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2004 |
Gender difference in the non-specific and specific immune response in humans.
Topics: Adult; Calcimycin; Cytokines; Female; Humans; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Sex Characteristics; Tetradecanoylphorbol Acetate | 2004 |
Inhibitory effects of cyclosporin A on calcium mobilization-dependent interleukin-8 expression and invasive potential of human glioblastoma U251MG cells.
Topics: Calcimycin; Calcium; Cell Division; Cell Line, Tumor; Cyclosporine; Glioblastoma; Humans; I-kappa B Kinase; Interleukin-8; Neoplasm Invasiveness; NF-kappa B; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Receptors, Interleukin-8A; Receptors, Interleukin-8B; RNA, Messenger; Tetradecanoylphorbol Acetate | 2004 |
Phorbol myristate acetate and calcium ionophore A23187-stimulated human T cells do not express high-affinity IL-2 receptors.
Topics: Adjuvants, Immunologic; Biological Assay; Calcimycin; Cells, Cultured; Humans; Ionophores; Lymphocyte Activation; Receptors, Interleukin-2; Stimulation, Chemical; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
The DHE cell line as a model for studying rat gastro-intestinal mucin expression: effects of dexamethasone.
Topics: Animals; Anti-Inflammatory Agents; Bethanechol; Blotting, Northern; Calcimycin; Carcinogens; Cell Line, Tumor; Dexamethasone; Gastric Mucins; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Intestinal Neoplasms; Ionophores; Muscarinic Agonists; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Species Specificity; Tetradecanoylphorbol Acetate | 2004 |
Timing of MAP kinase inactivation effects on emission of polar body in porcine oocytes activated by Ca2+ ionophore.
Topics: Animals; Butadienes; Calcimycin; Calcium; CDC2 Protein Kinase; Female; Ionophores; Male; Mitogen-Activated Protein Kinases; Nitriles; Oocytes; Protein Kinase Inhibitors; Sperm Injections, Intracytoplasmic; Swine; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Expression of cytosolic phospholipase A2 alpha in murine C12 cells, a variant of L929 cells, induces arachidonic acid release in response to phorbol myristate acetate and Ca2+ ionophores, but not to tumor necrosis factor-alpha.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Cell Line; Cytosol; Gene Expression Regulation, Enzymologic; Group IV Phospholipases A2; Humans; Ionophores; Isoenzymes; Mice; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2004 |
Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: involvement in the regulation of cyclooxygenase-2.
Topics: Amino Acid Sequence; Calcimycin; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 2; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Molecular Sequence Data; NFATC Transcription Factors; Nuclear Proteins; Peptide Fragments; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Sequence Deletion; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription Factors | 2005 |
Inhibitory effect of inflammatory cytokines production from activated mast cells by Gamisopoonghwanghyul-tang.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Cell Line; Cell Survival; Cytokines; Humans; Interleukin-1; Interleukin-10; Interleukin-6; Korea; Mast Cells; Medicine, East Asian Traditional; Plant Extracts; Plant Preparations; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2004 |
Cyclooxygenase-2 inhibitor SC-236 [4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1-pyrazol-1-l] benzenesulfonamide] suppresses nuclear factor-kappaB activation and phosphorylation of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase,
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Calcimycin; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Dual Specificity Phosphatase 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; Immunohistochemistry; Ionophores; JNK Mitogen-Activated Protein Kinases; Luciferases; Mast Cells; Membrane Proteins; Microscopy, Confocal; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA; Stimulation, Chemical; Sulfonamides; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Thiazoles | 2005 |
Complexin II facilitates exocytotic release in mast cells by enhancing Ca2+ sensitivity of the fusion process.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Calcimycin; Calcium; Cell Degranulation; Cell Line, Tumor; Cell Membrane; Cytoplasm; Exocytosis; Mast Cells; Membrane Fusion; Nerve Tissue Proteins; Protein Transport; Rats; Tetradecanoylphorbol Acetate | 2005 |
Anti-inflammatory activity of Korean folk medicine 'Sabaeksan'.
Topics: Anti-Inflammatory Agents; Blotting, Western; Calcimycin; Carcinogens; Cell Line; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Ionophores; Korea; Mast Cells; Medicine, East Asian Traditional; NF-kappa B; Plant Extracts; Tetradecanoylphorbol Acetate | 2005 |
Anti-allergic effects of Lycopus lucidus on mast cell-mediated allergy model.
Topics: Administration, Rectal; Animals; Anti-Allergic Agents; Calcimycin; Calcium; Cell Line; Dinitrophenols; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Eruptions; Drug Hypersensitivity; Drugs, Chinese Herbal; Histamine Release; Humans; I-kappa B Proteins; Injections, Intraperitoneal; Interleukin-6; Lycopus; Male; Mast Cells; Mice; Mice, Inbred ICR; NF-kappa B; NF-KappaB Inhibitor alpha; p-Methoxy-N-methylphenethylamine; p38 Mitogen-Activated Protein Kinases; Phytotherapy; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2005 |
TCR pathway involves ICBP90 gene down-regulation via E2F binding sites.
Topics: Base Sequence; Binding Sites; Calcimycin; Calcium; CCAAT-Enhancer-Binding Proteins; Cell Cycle Proteins; Cyclin D3; Cyclins; DNA Primers; DNA-Binding Proteins; Down-Regulation; E2F Transcription Factors; Humans; Jurkat Cells; Promoter Regions, Genetic; Receptors, Antigen, T-Cell; Retinoblastoma Protein; S Phase; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors; Ubiquitin-Protein Ligases | 2005 |
Adenosine inhibits the release of interleukin-1beta in activated human peripheral mononuclear cells.
Topics: Adenosine; Calcimycin; Humans; Interleukin-1; Monocytes; Phenethylamines; Purinergic P1 Receptor Agonists; Tetradecanoylphorbol Acetate | 2005 |
Cycloheximide-mediated sensitization to TNF-alpha-induced apoptosis in human colorectal cancer cell line COLO 205; role of FLIP and metabolic inhibitors.
Topics: Apoptosis; Calcimycin; Calcium; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cell Survival; Chelating Agents; Colorectal Neoplasms; Cycloheximide; Dactinomycin; Drug Synergism; Edetic Acid; Egtazic Acid; Enzyme Activation; Enzyme Activators; Humans; Ionophores; Protein Kinase C; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Escape; Tumor Necrosis Factor-alpha | 2005 |
Effects of the Chinese herbal formula Shi-Bi-Lin on cytokine release from the human mast cell line.
Topics: Anti-Allergic Agents; Calcimycin; Cell Line; Cytokines; Down-Regulation; Drugs, Chinese Herbal; Humans; Hypersensitivity; Interleukin-4; Ionophores; Mast Cells; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2005 |
Regulatory effects of cytokine production in atopic allergic reaction by gammi-danguieumja.
Topics: Animals; Anti-Allergic Agents; Calcimycin; Cell Line; Cell Survival; Cytokines; Drugs, Chinese Herbal; Histamine Release; Humans; Interferon-gamma; Interleukin-8; Ionophores; Mast Cells; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2004 |
White spot syndrome virus (WSSV) interaction with crayfish haemocytes.
Topics: Animals; Apoptosis; Astacoidea; Blood Proteins; Calcimycin; Cell Adhesion Molecules; Cell Degranulation; Cells, Cultured; Fresh Water; Gene Expression; Hematopoietic Stem Cells; Hemocytes; In Situ Hybridization; Ionophores; Male; Melanins; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; White spot syndrome virus 1 | 2006 |
Beta-agonists modulate T-cell functions via direct actions on type 1 and type 2 cells.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Antigens, CD; Calcimycin; Carcinogens; CD8-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Dinoprostone; Humans; Ionophores; Lymphocyte Activation; MAP Kinase Signaling System; NF-kappa B; Oxytocics; Protein Kinases; Receptors, Adrenergic, beta-2; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells | 2006 |
Presynaptic effects of anandamide and WIN55,212-2 on glutamatergic nerve endings isolated from rat hippocampus.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzoxazines; Calcimycin; Calcium Channel Blockers; Capsaicin; Endocannabinoids; Glutamates; Hippocampus; Male; Morpholines; Naphthalenes; Polyunsaturated Alkamides; Presynaptic Terminals; Rats; Rats, Wistar; Synaptosomes; Tetradecanoylphorbol Acetate | 2006 |
Calcium-dependent expression of TNF-alpha in neural cells is mediated by the calcineurin/NFAT pathway.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcineurin; Calcium; Calcium Channel Agonists; Calcium Signaling; Cycloheximide; Cyclosporine; Enzyme Inhibitors; Gene Expression Regulation; Humans; Immunosuppressive Agents; Ionophores; Neurons; NFATC Transcription Factors; Oligopeptides; PC12 Cells; Protein Synthesis Inhibitors; Rats; Tacrolimus; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2006 |
Action of Dracocephalum argunense on mast cell-mediated allergy model.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Blotting, Western; Calcimycin; Cyclic AMP; Histamine Release; Hypersensitivity; Immunoglobulin E; Interleukin-6; Lamiaceae; Male; Mast Cells; Mice; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; p38 Mitogen-Activated Protein Kinases; Passive Cutaneous Anaphylaxis; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2006 |
Anti-inflammatory effect of Poncirus trifoliata fruit through inhibition of NF-kappaB activation in mast cells.
Topics: Anti-Inflammatory Agents; Calcimycin; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Fruit; Gene Expression; Humans; Interleukin-6; Luciferases; Mast Cells; NF-kappa B; Plant Extracts; Poncirus; Pyrrolidines; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Thiocarbamates; Time Factors; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2006 |
Luteolin, a flavonoid, inhibits CD40 ligand expression by activated human basophils.
Topics: Apigenin; Basophils; Calcimycin; CD40 Ligand; Cell Line; Flavonoids; Flavonols; Humans; Interleukin-4; Luteolin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate | 2006 |
Gene expression of arachidonate cyclooxygenase pathway leading to the delayed synthesis of prostaglandins E2 and F2alpha in response to phorbol 12-myristate 13-acetate and action of these prostanoids during life cycle of adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Calcimycin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprost; Dinoprostone; Gene Expression Regulation, Enzymologic; Humans; Ionophores; Mice; Protein Isoforms; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triglycerides | 2006 |
Alginic acid has anti-anaphylactic effects and inhibits inflammatory cytokine expression via suppression of nuclear factor-kappaB activation.
Topics: Alginates; Animals; Anti-Allergic Agents; Blotting, Western; Calcimycin; Cell Line; Cytokines; Glucuronic Acid; Hexuronic Acids; Histamine Release; Histidine Decarboxylase; Ionophores; Male; Mast Cells; Models, Animal; NF-kappa B; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Peritoneum; Rats; Rats, Wistar; Skin Tests; Tetradecanoylphorbol Acetate | 2006 |
Polymorphonuclear leukocyte dysfunction syndrome in patients with increasing sepsis severity.
Topics: C-Reactive Protein; Calcimycin; Calcitonin; CD18 Antigens; Humans; Hydrogen Peroxide; Interleukin-6; Leukocyte Count; Middle Aged; Multiple Organ Failure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Opsonin Proteins; Phagocytosis; Protein Precursors; Sepsis; Severity of Illness Index; Shock, Septic; Syndrome; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 2006 |
Hydrogen peroxide-induced arachidonic acid release in L929 cells; roles of Src, protein kinase C and cytosolic phospholipase A2alpha.
Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Cell Line, Tumor; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Group IV Phospholipases A2; Humans; Hydrogen Peroxide; Indoles; Ionophores; Maleimides; Mice; Phospholipases A; Protein Kinase C; Protein Kinase C-alpha; Protein Transport; Pyrimidines; Pyrrolidines; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate; Transfection | 2006 |
Artemisia iwayomogi inhibits immediate-type allergic reaction and inflammatory cytokine secretion.
Topics: Animals; Artemisia; Calcimycin; Cell Line, Tumor; Cytokines; Histamine Release; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Male; Mast Cells; Mice; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2006 |
Distinct role of IL-3 promoter and enhancer region in murine mast cells.
Topics: Animals; Base Sequence; Calcimycin; Cyclosporine; Deoxyribonuclease I; Enhancer Elements, Genetic; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-3; Mast Cells; Mice; Molecular Sequence Data; Promoter Regions, Genetic; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 2007 |
Role of phosphatidylinositol 4,5-bisphosphate in the activation of cytosolic phospholipase A2-alpha.
Topics: Animals; Arachidonic Acids; Base Sequence; Binding Sites; Calcimycin; Calcium; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cytosol; Enzyme Activation; Epidermal Growth Factor; Group IV Phospholipases A2; Ionophores; Isoenzymes; Membrane Lipids; Phosphatidylinositol 4,5-Diphosphate; Phospholipase C delta; Phospholipases A; Phospholipases A2; Phosphorylation; Prostaglandins; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2006 |
Concomitant activation of extracellular signal-regulated kinase and induction of COX-2 stimulates maximum prostaglandin E2 synthesis in human airway epithelial cells.
Topics: Calcimycin; Calcium; Cyclooxygenase 2; Dinoprostone; Enzyme Induction; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-1beta; Ionophores; Kinetics; Lipopolysaccharides; Phospholipases A; Phosphorylation; Pneumonia; Protein Kinase C; Respiratory System; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2006 |
Neutrophil activator of matrix metalloproteinase-2 (NAM).
Topics: Adult; Amides; Calcimycin; Cathepsin G; Cathepsins; Cells, Cultured; Culture Media, Conditioned; Endothelium, Vascular; Enzyme Activation; Enzyme Precursors; Humans; Inflammation; Ionomycin; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Neoplasm Invasiveness; Neoplasm Metastasis; Neutrophils; Oligopeptides; Pancreatic Elastase; Phenylalanine; Protease Inhibitors; Proteins; RNA, Messenger; Serine Endopeptidases; Substrate Specificity; Tetradecanoylphorbol Acetate; Thiophenes; Tissue Inhibitor of Metalloproteinase-2; Umbilical Veins | 2006 |
DA-9601 inhibits activation of the human mast cell line HMC-1 through inhibition of NF-kappaB.
Topics: Artemisia; Calcimycin; Cell Line; Cytokines; Gene Expression; Humans; Inflammation Mediators; Mast Cells; NF-kappa B; Plant Extracts; Tetradecanoylphorbol Acetate | 2007 |
Use of scopoletin to inhibit the production of inflammatory cytokines through inhibition of the IkappaB/NF-kappaB signal cascade in the human mast cell line HMC-1.
Topics: Anti-Inflammatory Agents; Calcimycin; Cell Degranulation; Cell Line; Cell Survival; Histamine; Humans; I-kappa B Proteins; Interleukin-6; Interleukin-8; Mast Cells; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Scopoletin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Epigallocatechin-3-gallate inhibits secretion of TNF-alpha, IL-6 and IL-8 through the attenuation of ERK and NF-kappaB in HMC-1 cells.
Topics: Calcimycin; Calcium; Catechin; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Humans; Interleukin-6; Interleukin-8; Ionophores; NF-kappa B; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Effects of the Schisandra fructus water extract on cytokine release from a human mast cell line.
Topics: Calcimycin; Cell Line, Tumor; Culture Media, Conditioned; Cytokines; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; I-kappa B Proteins; Interleukin-6; Leukemia, Mast-Cell; Mast Cells; NF-kappa B; Plant Extracts; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schisandra; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Water | 2006 |
(S)-armepavine inhibits human peripheral blood mononuclear cell activation by regulating Itk and PLCgamma activation in a PI-3K-dependent manner.
Topics: Alkaloids; Benzylisoquinolines; Calcimycin; Calcium; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Interferon-gamma; Interleukin-2; Leukocytes, Mononuclear; Molecular Conformation; Molecular Weight; Nelumbo; NF-kappa B; NFATC Transcription Factors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; RNA, Messenger; Seeds; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2007 |
HaCaT keratinocytes overexpressing the S100 proteins S100A8 and S100A9 show increased NADPH oxidase and NF-kappaB activities.
Topics: Calcimycin; Calgranulin A; Calgranulin B; Cells, Cultured; Humans; Interleukin-8; Keratinocytes; NADPH Oxidases; NF-kappa B; Phosphoproteins; Reactive Oxygen Species; RNA, Messenger; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 2007 |
[Influence of signal transduction modulators on the secretory function of T lymphocytes in severely scalded mice and its mechanism].
Topics: Animals; Benzoquinones; Burns; Calcimycin; Calcium; Cells, Cultured; Female; Flavonoids; Interleukin-10; Interleukin-2; Lactams, Macrocyclic; Lymphocyte Activation; Male; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinase Kinases; Protein Kinase C; Protein-Tyrosine Kinases; Rifabutin; Signal Transduction; Spleen; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2006 |
Inhibitory effect of fulvic acid extracted from Canadian sphagnum peat on chemical mediator release by RBL-2H3 and KU812 cells.
Topics: Animals; Anti-Allergic Agents; Antigen-Antibody Complex; Antigens; Basophils; Benzopyrans; beta-N-Acetylhexosaminidases; Calcimycin; Calcium; Cell Line, Tumor; Dose-Response Relationship, Drug; Fluorescent Dyes; Formazans; Histamine Release; Humans; Immunoglobulin E; Ionophores; Leukemia, Basophilic, Acute; Leukemia, Experimental; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Nuclear Magnetic Resonance, Biomolecular; p-Methoxy-N-methylphenethylamine; Plant Extracts; Rats; Spectroscopy, Fourier Transform Infrared; Sphagnopsida; Tetradecanoylphorbol Acetate; Tetrazolium Salts | 2007 |
Platelet particle formation by anti GPIIIa49-66 Ab, Ca2+ ionophore A23187, and phorbol myristate acetate is induced by reactive oxygen species and inhibited by dexamethasone blockade of platelet phospholipase A2, 12-lipoxygenase, and NADPH oxidase.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Arachidonate 12-Lipoxygenase; Blood Platelets; Calcimycin; Carcinogens; Cell Membrane; Cytosol; Dexamethasone; Group IV Phospholipases A2; Humans; Integrin beta3; Ionophores; Lipoxygenase Inhibitors; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Protein Transport; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Thrombocytopenia | 2007 |
Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-kappaB and p38 MAPK in HMC-1 human mast cell line.
Topics: Calcimycin; Carcinogens; Cell Line; Cytokines; Enzyme Activation; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; Ionophores; Mast Cells; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Quercetin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Hesperidin inhibits expression of hypoxia inducible factor-1 alpha and inflammatory cytokine production from mast cells.
Topics: Calcimycin; Cell Survival; Cells, Cultured; Citrus; Cytokines; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Gene Expression; HeLa Cells; Hesperidin; HL-60 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation Mediators; Ionophores; Mast Cells; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2007 |
The role of protein kinase C isoenzymes in the regulation of calcineurin activity in human peripheral blood mononuclear cells.
Topics: Adaptor Proteins, Signal Transducing; Base Sequence; Calcimycin; Calcineurin; Calcineurin Inhibitors; Carbazoles; DNA Primers; Enzyme Activation; Humans; In Vitro Techniques; Indoles; Ionophores; Isoenzymes; Leukocytes, Mononuclear; Maleimides; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 2007 |
Regulation of activin receptor-interacting protein 2 expression in mouse hepatoma Hepa1-6 cells and its relationship with collagen type IV.
Topics: Activin Receptors, Type II; Activins; Adaptor Proteins, Signal Transducing; Adenylyl Cyclases; Animals; Calcimycin; Calcium; Carcinoma, Hepatocellular; Cell Line, Tumor; Colforsin; Collagen Type IV; Enzyme Activators; Gene Expression Regulation, Neoplastic; Ionophores; Kinetics; Lipopolysaccharides; Liver Neoplasms; Membrane Proteins; Mice; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection | 2007 |
Establishment of an in vitro test system to evaluate the down-regulatory activities of natural products on IL-4.
Topics: Animals; Anti-Allergic Agents; Calcimycin; Cell Line; Interleukin-4; Plant Extracts; Promoter Regions, Genetic; Rats; Tetradecanoylphorbol Acetate | 2007 |
Immunogold electron microscopic demonstration of distinct submembranous localization of the activated gammaPKC depending on the stimulation.
Topics: Animals; Calcimycin; Calcium; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Enzyme Activation; Enzyme Activators; Ionophores; Isoenzymes; Microscopy, Confocal; Microscopy, Electron; Microscopy, Fluorescence; N-Methylaspartate; Protein Kinase C; Protein Transport; Receptors, N-Methyl-D-Aspartate; Subcellular Fractions; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 2008 |
Adenosine inhibits the release of arachidonic acid and its metabolites (AAM) in activated human peripheral mononuclear cells.
Topics: Adenosine; Arachidonic Acid; Calcimycin; Calcium; Cyclic AMP; Humans; In Vitro Techniques; Ionophores; Monocytes; Protein Kinase C; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Tetradecanoylphorbol Acetate | 2007 |
Regulation of cytosolic phospholipase A2alpha by hsp90 and a p54 kinase in okadaic acid-stimulated macrophages.
Topics: Animals; Arachidonic Acid; Benzoquinones; Calcimycin; Calcium; Carcinogens; Cytosol; Enzyme Activation; Enzyme Inhibitors; Female; Golgi Apparatus; Green Fluorescent Proteins; Group IV Phospholipases A2; HSP90 Heat-Shock Proteins; Immunoblotting; Immunoprecipitation; Ionophores; Lactams, Macrocyclic; Macrophages, Peritoneal; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 10; NIH 3T3 Cells; Okadaic Acid; Phosphoamino Acids; Phosphorylation; Protein Transport; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Zymosan | 2008 |
Oxidative burst assessment and neutrophil-platelet complexes in unlysed whole blood.
Topics: Anthraquinones; Antibodies, Monoclonal; Blood Platelets; Calcimycin; Carcinogens; Flow Cytometry; Humans; Ionophores; Leukocyte Common Antigens; Lipopolysaccharide Receptors; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Reactive Oxygen Species; Respiratory Burst; Rhodamines; Sensitivity and Specificity; Tetradecanoylphorbol Acetate; Zymosan | 2008 |
Receptor for advanced glycation end products is subjected to protein ectodomain shedding by metalloproteinases.
Topics: ADAM Proteins; ADAM10 Protein; Alternative Splicing; Alzheimer Disease; Amyloid Precursor Protein Secretases; Calcimycin; Carcinogens; Cell Line; Cell Membrane; Diabetes Complications; Humans; Hydroxamic Acids; Ionophores; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Protease Inhibitors; Protein Isoforms; Protein Structure, Tertiary; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Small Interfering; Tetradecanoylphorbol Acetate | 2008 |
Inhibition of superoxide generation and myeloperoxidase release by carvedilol after receptor and nonreceptor stimulation of human neutrophils.
Topics: Adrenergic beta-Antagonists; Androstadienes; Calcimycin; Carbazoles; Carvedilol; Humans; In Vitro Techniques; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidants; Peroxidase; Phosphatidylinositol 3-Kinases; Propanolamines; Protein Kinase C; Receptors, Adrenergic, beta; Stimulation, Chemical; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin | 2008 |
Anti-inflammatory activity of Korean folk medicine purple bamboo salt.
Topics: Anti-Inflammatory Agents; Calcimycin; Calcium; Cell Line; Cytokines; Dose-Response Relationship, Drug; Humans; Interleukin-1beta; Interleukin-6; Ionophores; Mast Cells; Medicine, Korean Traditional; Plant Extracts; RNA, Messenger; Sasa; Sodium Chloride; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2003 |
Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells.
Topics: Calcimycin; Cell Line; Cells, Cultured; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Epinephrine; Factor VIII; Flow Cytometry; Genetic Vectors; Green Fluorescent Proteins; Humans; Ionophores; Lentivirus; Microscopy, Confocal; Microscopy, Fluorescence; Neovascularization, Physiologic; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; von Willebrand Factor; Weibel-Palade Bodies | 2009 |
Anti-inflammatory mechanisms of resveratrol in activated HMC-1 cells: pivotal roles of NF-kappaB and MAPK.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Calcium; Cell Line; Cyclooxygenase 2; Enzyme Activation; Humans; I-kappa B Kinase; Interleukin-6; Interleukin-8; Mast Cells; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Anti-inflammatory activity of Motherwort (Leonurus sibiricus L.).
Topics: Anti-Inflammatory Agents; Calcimycin; Humans; Inflammation; Interleukin-6; Interleukin-8; Leonurus; Mast Cells; Medicine, Traditional; NF-kappa B; Phytotherapy; Plant Extracts; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Effect of leaves of Eriobotrya japonica on anaphylactic allergic reaction and production of tumor necrosis factor-alpha.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Calcimycin; Eriobotrya; Histamine; Histamine Release; Humans; Immunoglobulin E; Male; Mast Cells; Mice; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Plant Leaves; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Early antiallergic inflammatory effects of Rhus verniciflua Stokes on human mast cells.
Topics: Anti-Allergic Agents; Calcimycin; Cell Line; Humans; Interleukin-6; Interleukin-8; Mast Cells; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; Plant Extracts; Rhus; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Anti-inflammatory activity of ethanol extract from Geranium sibiricum Linne.
Topics: Anti-Inflammatory Agents; Calcimycin; Cell Line; Cyclooxygenase 2; Drug Evaluation, Preclinical; Ethanol; Geranium; Humans; Interleukin-1beta; MAP Kinase Signaling System; Mast Cells; Mitogen-Activated Protein Kinase 1; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Extracts; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2009 |
Apoptotic inducers activate the release of D-aspartate through a hypotonic stimulus-triggered mechanism in PC12 cells.
Topics: Animals; Apoptosis; Aspartic Acid; Calcimycin; Hydrogen Peroxide; Hypotonic Solutions; Ion Channels; Ionophores; Nitrobenzoates; PC12 Cells; Rats; Sphingosine; Staurosporine; Stereoisomerism; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Uric Acid | 2009 |
Inhibitory effect of the alkaloid warifteine purified from Cissampelos sympodialis on B lymphocyte function in vitro and in vivo.
Topics: Adenylyl Cyclases; Alkaloids; Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Calcimycin; Cell Culture Techniques; Cell Proliferation; Cissampelos; Colforsin; Cyclic AMP; Extracellular Signal-Regulated MAP Kinases; Ficoll; Immunoglobulins; Immunologic Factors; Ionophores; Ligands; Lipopolysaccharides; Mice; Mice, Inbred BALB C; NF-kappa B; Phosphorylation; Plant Extracts; Plant Leaves; Signal Transduction; Spleen; Tetradecanoylphorbol Acetate; Toll-Like Receptors; Trinitrobenzenes | 2010 |
Persistency and pathway of isoflurane-induced inhibition of superoxide production by neutrophils.
Topics: Anesthetics, Inhalation; Animals; Calcimycin; Dogs; Isoflurane; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Spectrophotometry; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 2010 |
Ellagic acid inhibits lipopolysaccharide-induced expression of enzymes involved in the synthesis of prostaglandin E2 in human monocytes.
Topics: Calcimycin; Cyclooxygenase 2; Dinoprostone; Ellagic Acid; Humans; Intramolecular Oxidoreductases; Kinetics; Lipopolysaccharides; Microsomes; Monocytes; Phospholipases A2; Prostaglandin-E Synthases; Subcellular Fractions; Tetradecanoylphorbol Acetate | 2010 |
The identification of inhibitors of Schistosoma mansoni miracidial transformation by incorporating a medium-throughput small-molecule screen.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Anthelmintics; Benzophenanthridines; Calcimycin; Calcium Channel Blockers; Citalopram; Clomipramine; Colforsin; Cyclic AMP; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Immunohistochemistry; Mice; Schistosoma mansoni; Tetradecanoylphorbol Acetate; Triflupromazine | 2010 |
Libanoridin inhibits the mast cell-mediated allergic inflammatory reaction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Calcimycin; Cell Culture Techniques; Cell Line; Cell Survival; Corydalis; Coumarins; Cytokines; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Hypersensitivity; Inhibitory Concentration 50; Ionophores; Mast Cells; Medicine, Korean Traditional; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2010 |
Luteolin isolated from the flowers of Lonicera japonica suppresses inflammatory mediator release by blocking NF-kappaB and MAPKs activation pathways in HMC-1 cells.
Topics: Calcimycin; Calcium; Cell Line; Cyclooxygenase 2; Cytokines; Enzyme Activation; Flowers; Gene Expression Regulation; Humans; Inflammation Mediators; Intracellular Space; Lonicera; Luteolin; Mitogen-Activated Protein Kinases; NF-kappa B; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 2010 |
Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-kappaB in activated human mast cells: suppression of tumor necrosis factor-alpha, interleukin (IL)-6, and IL-8.
Topics: Butea; Calcimycin; Chalcones; Chromatography, Thin Layer; Enzyme-Linked Immunosorbent Assay; Flavonoids; Gas Chromatography-Mass Spectrometry; Gene Expression; Humans; I-kappa B Kinase; Inflammation; Interleukin-6; Interleukin-8; Mast Cells; NF-kappa B; Plant Extracts; Plants, Medicinal; Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
Inhibitory effect of acteoside isolated from Cistanche tubulosa on chemical mediator release and inflammatory cytokine production by RBL-2H3 and KU812 cells.
Topics: Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Calcimycin; Calcium; Catechols; Cell Line; Cistanche; Enzyme-Linked Immunosorbent Assay; Glucosides; Glycosides; Histamine; Humans; Interleukin-4; Phenols; Rats; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2010 |
The regulatory mechanism of β-eudesmol is through the suppression of caspase-1 activation in mast cell-mediated inflammatory response.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Calcimycin; Caspase Inhibitors; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Immunity, Cellular; Interleukin-6; Mast Cells; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Sesquiterpenes, Eudesmane; Tetradecanoylphorbol Acetate | 2011 |
VEGF stimulates RCAN1.4 expression in endothelial cells via a pathway requiring Ca2+/calcineurin and protein kinase C-delta.
Topics: Anti-Bacterial Agents; Calcimycin; Calcineurin; Calcium; Cell Line; Cell Proliferation; Cells, Cultured; DNA-Binding Proteins; Endothelial Cells; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Muscle Proteins; Phosphorylation; Protein Kinase C-delta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2010 |
Inhibitory effects of chelidonic acid on IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells.
Topics: Calcimycin; Calcium Ionophores; Carcinogens; Caspase 1; Caspase Inhibitors; Cell Line; Chelidonium; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Interleukin-6; Mast Cells; NF-kappa B; Pyrans; Rhizome; Tetradecanoylphorbol Acetate | 2011 |
Gomisin N has anti-allergic effect and inhibits inflammatory cytokine expression in mouse bone marrow-derived mast cells.
Topics: Animals; Anti-Allergic Agents; Bone Marrow Cells; Calcimycin; Calcium Ionophores; Carcinogens; Cells, Cultured; Cyclooctanes; Gene Expression Regulation; Hypersensitivity; Inflammation; Inflammation Mediators; Interleukin-6; Lignans; Male; Mast Cells; Mice; Mice, Inbred BALB C; Polycyclic Compounds; Tetradecanoylphorbol Acetate | 2011 |
Thymic stromal lymphopoietin is expressed and produced by caspase-1/NF-κB pathway in mast cells.
Topics: Calcimycin; Caspase 1; Cell Line; Cytokines; Gene Expression Regulation; Humans; Inflammation; Ionophores; Mast Cells; NF-kappa B; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Time Factors | 2011 |
Novel phosphorylation of aquaporin-5 at its threonine 259 through cAMP signaling in salivary gland cells.
Topics: Amino Acid Substitution; Animals; Antibodies; Antibody Specificity; Aquaporin 5; Calcimycin; Cell Line, Tumor; Cell Membrane; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Detergents; Humans; Isoproterenol; Isoquinolines; Male; Mice; Mice, Inbred ICR; Parotid Gland; Phosphorylation; Pilocarpine; Protein Kinase Inhibitors; Protein Transport; Salivary Glands; Signal Transduction; Submandibular Gland; Sulfonamides; Tetradecanoylphorbol Acetate; Threonine; Transfection | 2011 |
15-Deoxy-Δ(12,14)-prostaglandin J(2) interferes inducible synthesis of prostaglandins E(2) and F(2α) that suppress subsequent adipogenesis program in cultured preadipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Arachidonic Acid; Calcimycin; Cell Proliferation; Chromans; Dinoprost; Dinoprostone; Gene Expression; Ionophores; Isoenzymes; Lipid Metabolism; Mice; NF-kappa B; PPAR gamma; Proline; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Tetradecanoylphorbol Acetate; Thiazolidinediones; Thiocarbamates; Triglycerides; Troglitazone | 2011 |
Fritillaria ussuriensis extract inhibits the production of inflammatory cytokine and MAPKs in mast cells.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; Calcimycin; Fritillaria; Histamine Release; Hypersensitivity; Inflammation; Interleukin-6; Interleukin-8; Male; Mast Cells; Mitogen-Activated Protein Kinase Kinases; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Phosphorylation; Phytotherapy; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2011 |
Epigallocatechin-3-O-gallate inhibits the production of thymic stromal lymphopoietin by the blockade of caspase-1/NF-κB pathway in mast cells.
Topics: Blotting, Western; Calcimycin; Caspase Inhibitors; Caspases; Catechin; Cell Line; Cytokines; Gene Expression; Genes, Reporter; Humans; Luciferases; Mast Cells; NF-kappa B; Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2012 |
Anti-allergic effect of lambertianic acid from Thuja orientalis in mouse bone marrow-derived mast cells.
Topics: Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Bone Marrow Cells; Calcimycin; Carboxylic Acids; Cell Degranulation; Cyclooxygenase 2; Gene Dosage; Interleukin-6; Leukotriene C4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Naphthalenes; Prostaglandin D2; Tetradecanoylphorbol Acetate; Thuja | 2012 |
The suppression of thymic stromal lymphopoietin expression by selenium.
Topics: Calcimycin; Caspase 1; Cells, Cultured; Cytokines; Down-Regulation; Enzyme Activation; Genes, Reporter; Humans; Luciferases, Renilla; Mast Cells; NF-kappa B; Selenium; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2012 |
Effects of Angelica acutiloba on mast cell-mediated allergic reactions in vitro and in vivo.
Topics: Angelica; Animals; Calcimycin; Calcium Ionophores; Carcinogens; Cell Line; Complex Mixtures; Cytokines; Extracellular Signal-Regulated MAP Kinases; Histamine Release; Humans; Hypersensitivity; Male; MAP Kinase Kinase 4; Mast Cells; Phosphorylation; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2012 |
Anti-allergic effect of a chloroform-soluble extract of Cinnamomum cambodianum in bone marrow-derived mast cells.
Topics: Animals; Bone Marrow Cells; Calcimycin; Calcium Ionophores; Carcinogens; Chloroform; Cinnamomum; Complex Mixtures; Cyclooxygenase 2; Female; Gene Expression Regulation, Enzymologic; Hypersensitivity; Interleukin-6; Leukotriene C4; Mast Cells; Mice; Mice, Inbred BALB C; Prostaglandin D2; Tetradecanoylphorbol Acetate | 2012 |
Antiallergic effects of Scutellaria baicalensis on inflammation in vivo and in vitro.
Topics: Administration, Oral; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Blotting, Western; Calcimycin; Calcium Ionophores; Cells, Cultured; Dermatitis, Allergic Contact; Dinitrophenols; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Female; Haptens; Histamine Release; Humans; Inflammation Mediators; Interleukin-8; Mast Cells; Mitogen-Activated Protein Kinases; p-Methoxy-N-methylphenethylamine; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Scutellaria baicalensis; Serum Albumin; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
Lipoteichoic acid of Staphylococcus aureus enhances IL-6 expression in activated human basophils.
Topics: Basophils; Calcimycin; Calcium Ionophores; Cell Line; Drug Synergism; Gene Expression; Humans; Interleukin-6; Lipopolysaccharide Receptors; Lipopolysaccharides; NF-kappa B; Protein Kinase C; Protein Kinase Inhibitors; Signal Transduction; Staphylococcus aureus; Teichoic Acids; Tetradecanoylphorbol Acetate; Toll-Like Receptor 2; Transcription Factor AP-1 | 2012 |
In vitro ultraviolet A irradiation decreases both release ability and gene-expression of vascular endothelial growth factor-A from mast cells.
Topics: Calcimycin; Calcium Ionophores; Carcinogens; Cell Line, Tumor; Dose-Response Relationship, Radiation; Gene Expression Regulation; Humans; Mast Cells; RNA, Messenger; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Vascular Endothelial Growth Factor A | 2012 |
Anti-allergic activity of crystallinity controlled N-acetyl glucosamine.
Topics: Acetylglucosamine; Anaphylaxis; Animals; Anti-Allergic Agents; Calcimycin; Calcium Ionophores; Carcinogens; Caspase 1; Cell Line; Enzyme Activation; Gene Expression Regulation; Hexosaminidases; Histamine; Humans; Interleukin-1beta; Male; Mast Cells; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetradecanoylphorbol Acetate | 2012 |
The Src kinase Yes is activated in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters, but not pancreatic growth factors, which stimulate its association with numerous other signaling molecules.
Topics: Acinar Cells; Animals; Bombesin; Calcimycin; Calcium Ionophores; Calcium Signaling; Carbachol; Cholecystokinin; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Gastrointestinal Hormones; Indoles; Intercellular Signaling Peptides and Proteins; Male; Maleimides; Neurotransmitter Agents; Pancreas; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-yes; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin | 2012 |
Nuclear factor of activated T-cell c3 inhibition of mammalian target of rapamycin signaling through induction of regulated in development and DNA damage response 1 in human intestinal cells.
Topics: Calcimycin; Calcineurin Inhibitors; Cell Differentiation; Cyclosporine; Gene Expression Regulation; HCT116 Cells; HT29 Cells; Humans; Intestinal Mucosa; Intestines; NFATC Transcription Factors; Signal Transduction; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Transcription Factors; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2012 |
Annexin A7 and SNAP23 interactions in alveolar type II cells and in vitro: a role for Ca(2+) and PKC.
Topics: Alveolar Epithelial Cells; Animals; Annexin A7; Antibodies; ATP-Binding Cassette Transporters; Calcimycin; Calcium; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase Inhibitors; Protein Structure, Tertiary; Protein Transport; Rats; Rats, Sprague-Dawley; SNARE Proteins; Tetradecanoylphorbol Acetate; Vesicular Transport Proteins | 2012 |
Macelignan inhibits histamine release and inflammatory mediator production in activated rat basophilic leukemia mast cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; beta-N-Acetylhexosaminidases; Calcimycin; Calcium; Cell Degranulation; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Histamine Release; Hypersensitivity; Inflammation Mediators; Interleukin-13; Interleukin-4; JNK Mitogen-Activated Protein Kinases; Leukemia, Basophilic, Acute; Leukotriene C4; Lignans; Mast Cells; Myristica; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-akt; Rats; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2012 |
Inhibitory effects of panduratin A on allergy-related mediator production in rat basophilic leukemia mast cells.
Topics: Animals; Arachidonate 5-Lipoxygenase; beta-N-Acetylhexosaminidases; Calcimycin; Calcium; Cell Degranulation; Cell Line, Tumor; Chalcones; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Histamine; Histamine Release; Hypersensitivity, Immediate; Immunoglobulin E; Inflammation Mediators; Interleukin-13; Interleukin-4; JNK Mitogen-Activated Protein Kinases; Leukemia, Basophilic, Acute; Leukotriene B4; Mast Cells; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Prostaglandins E; Proto-Oncogene Proteins c-akt; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zingiberaceae | 2012 |
Effects of schizandrin on the expression of thymic stromal lymphopoietin in human mast cell line HMC-1.
Topics: Blotting, Western; Calcimycin; Caspase 1; Cell Line; Cyclooctanes; Cytokines; Enzyme-Linked Immunosorbent Assay; Humans; Lignans; Luciferases; Mast Cells; Polycyclic Compounds; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2012 |
Anti-inflammatory and anti-allergic effect of Agaricus blazei extract in bone marrow-derived mast cells.
Topics: Agaricus; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; beta-N-Acetylhexosaminidases; Biological Products; Bone Marrow Cells; Calcimycin; Cell Degranulation; Down-Regulation; Female; Inflammation; Interleukin-6; Leukotriene C4; Mast Cells; Mice; Mice, Inbred BALB C; Phosphorylation; Phytotherapy; Prostaglandin D2; Proto-Oncogene Proteins c-akt; Tetradecanoylphorbol Acetate | 2012 |
Anti-inflammatory effect of sinomenine by inhibition of pro-inflammatory mediators in PMA plus A23187-stimulated HMC-1 Cells.
Topics: Anti-Inflammatory Agents; Calcimycin; Cells, Cultured; Cyclooxygenase 2; Humans; Inflammation Mediators; Morphinans; NF-kappa B; Phosphorylation; Tetradecanoylphorbol Acetate | 2012 |
Calcium ameliorates renal cyst growth in metanephric organ culture: a morphological study.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcimycin; Calcium; Calcium Channel Agonists; Kidney; Mice; Mice, Inbred BALB C; Microscopy, Electron, Transmission; Microscopy, Phase-Contrast; Organ Culture Techniques; Polycystic Kidney Diseases; Tetradecanoylphorbol Acetate | 2012 |
Differential inhibitory effects of 2-azafluorenones on PI-PLC activation but not on PC-PLC- or PC-PLD-activation induced by histamine, PAF, PMA or A23187 in C6 glioma cells.
Topics: Animals; Calcimycin; Cell Line, Tumor; Enzyme Activation; Fluorenes; Histamine; Phosphatidylcholines; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phospholipase D; Platelet Activating Factor; Rats; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases | 2013 |
The anti-inflammatory effect of Cheongseoikki-tang ethanol extract on allergic reactions mediated by bone marrow-derived mast cells.
Topics: Animals; Anti-Inflammatory Agents; beta-N-Acetylhexosaminidases; Bone Marrow Cells; Calcimycin; Cell Degranulation; Cell Survival; Drugs, Chinese Herbal; Hypersensitivity; Interleukin-6; Leukotriene C4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Prostaglandin D2; Tetradecanoylphorbol Acetate | 2013 |
Acteoside inhibits type Ι allergy through the down-regulation of Ca/NFAT and JNK MAPK signaling pathways in basophilic cells.
Topics: Animals; Anti-Allergic Agents; Basophils; Calcimycin; Calcium Ionophores; Cell Line; Cistanche; Down-Regulation; Glucosides; Humans; Hypersensitivity, Immediate; Interleukin-4; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; NFATC Transcription Factors; Phenols; Rats; Receptors, IgE; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2013 |
[6]-Shogaol inhibits the production of proinflammatory cytokines via regulation of NF-κB and phosphorylation of JNK in HMC-1 cells.
Topics: Animals; Calcimycin; Calcium Ionophores; Carcinogens; Catechols; Cell Line; Cytokines; Histamine Release; Humans; Inflammation; Male; MAP Kinase Kinase 4; Mast Cells; Mutagens; NF-kappa B; Phosphorylation; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2013 |
The ameliorative effect of sophoricoside on mast cell-mediated allergic inflammation in vivo and in vitro.
Topics: Animals; Anti-Inflammatory Agents; Benzopyrans; Calcimycin; Calcium Ionophores; Carcinogens; Caspase 1; Cell Line; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; Histamine; Humans; Irritants; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; NF-kappa B; Tetradecanoylphorbol Acetate | 2013 |
Houttuynia cordata Thunb inhibits the production of pro-inflammatory cytokines through inhibition of the NFκB signaling pathway in HMC-1 human mast cells.
Topics: Calcimycin; Cell Line; Cell Survival; Cytokines; Houttuynia; Humans; I-kappa B Proteins; Interleukin-6; Interleukin-8; Mast Cells; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Plant Extracts; Promoter Regions, Genetic; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2013 |
The antiallergic mechanisms of Citrus sunki and bamboo salt (K-ALL) in an allergic rhinitis model.
Topics: Administration, Intranasal; Administration, Oral; Anaphylaxis; Animals; Calcimycin; Calcium Ionophores; Carcinogens; Cell Line; Citrus; Cytokines; Disease Models, Animal; Gene Expression Regulation; Humans; Inflammation Mediators; Male; Mast Cells; Medicine, Korean Traditional; Mice; Mice, Inbred ICR; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic; Rhinitis, Allergic, Perennial; Tetradecanoylphorbol Acetate | 2014 |
Genuine traditional Korean medicine, Naju Jjok (Chung-Dae, Polygonum tinctorium) improves 2,4-dinitrofluorobenzene-induced atopic dermatitis-like lesional skin.
Topics: Administration, Oral; Animals; Calcimycin; Caspase 1; Cell Line; Cytokines; Dermatitis, Atopic; Dinitrofluorobenzene; Drug Evaluation, Preclinical; Humans; Male; Medicine, Korean Traditional; Mice; Phytotherapy; Plant Extracts; Polygonum; Receptor-Interacting Protein Serine-Threonine Kinase 2; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Tumor Necrosis Factor-alpha | 2014 |
Inhibitory effects of BiRyuChe-bang on mast cell-mediated allergic reactions and inflammatory cytokines production.
Topics: Animals; Calcimycin; Cells, Cultured; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Histamine Release; Humans; Inflammation Mediators; Male; Mast Cells; Mice; Mice, Inbred ICR; Monoterpenes; NF-kappa B; Passive Cutaneous Anaphylaxis; Peritoneum; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 2013 |
Stimulation of corticotropin-releasing factor gene expression by FosB in rat hypothalamic 4B cells.
Topics: Adenylyl Cyclases; Animals; Calcimycin; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Enzyme Activators; Gene Expression; Hypothalamus; Neuroendocrine Cells; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2014 |
Tryptanthrin ameliorates atopic dermatitis through down-regulation of TSLP.
Topics: Animals; Calcimycin; Calcium Ionophores; Cell Line; Cytokines; Dermatitis, Atopic; Dinitrofluorobenzene; Down-Regulation; Humans; Male; Mast Cells; Mice; Quinazolines; Skin; Spleen; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2014 |
Hyperoside regulates the level of thymic stromal lymphopoietin through intracellular calcium signalling.
Topics: Calcimycin; Calcium; Calcium Ionophores; Calcium Signaling; Caspase 1; Cell Line; Crataegus; Cytokines; Humans; Interleukin-1beta; Interleukin-6; Mast Cells; NF-kappa B; Quercetin; Receptor-Interacting Protein Serine-Threonine Kinase 2; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2014 |
Human mast cell line-1 (HMC-1) cells exhibit a membrane capacitance increase when dialysed with high free-Ca(2+) and GTPγS containing intracellular solution.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Calcimycin; Calcium; Cell Degranulation; Cell Line; Cell Membrane; Electric Capacitance; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Interleukin-1beta; Interleukin-8; Mast Cells; Renal Dialysis; Tetradecanoylphorbol Acetate; Thiazolidines | 2013 |
Tetrandrine suppresses pro-inflammatory mediators in PMA plus A23187-induced HMC-1 cells.
Topics: Benzylisoquinolines; Calcimycin; Cell Line; Cyclooxygenase 2; Humans; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Mast Cells; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Tetradecanoylphorbol Acetate | 2014 |
Anti-inflammatory and antipruritic effects of luteolin from Perilla (P. frutescens L.) leaves.
Topics: Animals; Anti-Inflammatory Agents; Antipruritics; Calcimycin; Humans; Interleukin-1beta; Luteolin; Male; Mast Cells; Mice; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Perilla; Pruritus; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Zinc oxide nanoparticles, a novel candidate for the treatment of allergic inflammatory diseases.
Topics: Animals; Anti-Inflammatory Agents; Calcimycin; Caspase 1; Cell Line; Cytokines; Enzyme Activation; Gene Expression Regulation; Humans; Hypersensitivity; I-kappa B Kinase; Inflammation; Male; Mast Cells; Mice; Mitogen-Activated Protein Kinases; Nanoparticles; NF-kappa B; Passive Cutaneous Anaphylaxis; Phosphorylation; Proteolysis; Receptor-Interacting Protein Serine-Threonine Kinase 2; RNA, Messenger; Tetradecanoylphorbol Acetate; Zinc Oxide | 2014 |
Suppressive effects of britanin, a sesquiterpene compound isolated from Inulae flos, on mast cell-mediated inflammatory responses.
Topics: Administration, Ophthalmic; Animals; Calcimycin; Calcium Ionophores; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Humans; Hypersensitivity, Immediate; Inflammation; Inflammation Mediators; Inula; Lactones; Male; Mast Cells; Mice, Inbred ICR; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Passive Cutaneous Anaphylaxis; Phosphorylation; Phytotherapy; Sesquiterpenes; Tetradecanoylphorbol Acetate | 2014 |
Genistein inhibits pro‑inflammatory cytokines in human mast cell activation through the inhibition of the ERK pathway.
Topics: Blotting, Western; Calcimycin; Cell Line, Tumor; Cytokines; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Genistein; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; MAP Kinase Signaling System; Mast Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phytoestrogens; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Flavonoids and arylbenzofurans from the rhizomes and roots of Sophora tonkinensis with IL-6 production inhibitory activity.
Topics: Benzofurans; Calcimycin; Cell Line; Flavanones; Flavonoids; Humans; Interleukin-6; Magnetic Resonance Spectroscopy; Mast Cells; Molecular Conformation; Plant Extracts; Plant Roots; Rhizome; Sophora; Terpenes; Tetradecanoylphorbol Acetate | 2014 |
Synergism between phorbol myristate acetate and calcium ionophore in inducing proliferation of in vitro γ-irradiated murine lymphocytes.
Topics: Animals; Calcimycin; Calcium Ionophores; Cell Proliferation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Synergism; Female; Gamma Rays; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Radiation Tolerance; Tetradecanoylphorbol Acetate | 2015 |
Synthesis, Anti-inflammatory Activities and Mechanisms of 3,5- dihydroxycinnamic Acid Derivatives.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Calcimycin; Cell Line; Cell Line, Tumor; Cell Survival; Cinnamates; Cyclooxygenase 2; Cytokines; Dinoprostone; Ear; Edema; Female; Lipopolysaccharides; Lipoxygenase Inhibitors; Mice, Inbred BALB C; Peroxidase; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate | 2015 |
Cordycepin Suppresses Thymic Stromal Lymphopoietin Expression via Blocking Caspase-1 and Receptor-Interacting Protein 2 Signaling Pathways in Mast Cells.
Topics: Calcimycin; Caspase 1; Cell Line; Cytokines; Deoxyadenosines; Gene Expression Regulation; Humans; I-kappa B Kinase; Keratinocytes; Mast Cells; NF-kappa B; Receptor-Interacting Protein Serine-Threonine Kinase 2; Signal Transduction; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin | 2016 |
Possible Involvement of the Inhibition of NF-κB Factor in Anti-Inflammatory Actions That Melatonin Exerts on Mast Cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Cell Line, Tumor; Interleukin-6; Mast Cells; Melatonin; NF-kappa B; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2016 |
Hydrogen sulfide diminishes the levels of thymic stromal lymphopoietin in activated mast cells.
Topics: Active Transport, Cell Nucleus; Animals; Calcimycin; Calcium; Caspase 1; Cell Line; Cytokines; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Hydrogen Sulfide; I-kappa B Proteins; Immunoglobulin E; Interleukin-6; Interleukin-8; Mast Cells; Medicine, Korean Traditional; Mice; Mice, Inbred BALB C; NF-kappa B; NF-KappaB Inhibitor alpha; Ovalbumin; Phosphorylation; Real-Time Polymerase Chain Reaction; Receptor-Interacting Protein Serine-Threonine Kinase 2; Rhinitis, Allergic; RNA, Messenger; Sulfides; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Tumor Necrosis Factor-alpha | 2016 |
Andrographolide suppresses thymic stromal lymphopoietin in phorbol myristate acetate/calcium ionophore A23187-activated mast cells and 2,4-dinitrofluorobenzene-induced atopic dermatitis-like mice model.
Topics: Animals; Calcimycin; Cell Proliferation; Cell Survival; Cytokines; Dermatitis, Atopic; Dinitrofluorobenzene; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Humans; Mast Cells; Mice; Molecular Conformation; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Tumor Cells, Cultured | 2016 |
Impact of simultaneous stimulation of 5-lipoxygenase and myeloperoxidase in human neutrophils.
Topics: Arachidonate 5-Lipoxygenase; Calcimycin; Cells, Cultured; Enzyme Activation; Glutathione; Humans; Hydrogen Peroxide; Neutrophils; Peroxidase; Tetradecanoylphorbol Acetate | 2016 |
Role of WW Domain-containing Oxidoreductase WWOX in Driving T Cell Acute Lymphoblastic Leukemia Maturation.
Topics: Active Transport, Cell Nucleus; Animals; Calcimycin; Cell Nucleus; Extracellular Signal-Regulated MAP Kinases; HEK293 Cells; Humans; Jurkat Cells; Mice; Multiprotein Complexes; NF-KappaB Inhibitor alpha; Oxidoreductases; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Domains; Proteolysis; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins; U937 Cells; WW Domain-Containing Oxidoreductase | 2016 |
Atractylodin Inhibits Interleukin-6 by Blocking NPM-ALK Activation and MAPKs in HMC-1.
Topics: Atractylodes; Calcimycin; Cell Line; Extracellular Signal-Regulated MAP Kinases; Furans; Humans; Interleukin-6; MAP Kinase Signaling System; Mast Cells; Phosphorylation; Protein-Tyrosine Kinases; Rhizome; Tetradecanoylphorbol Acetate | 2016 |
Characterization of neutrophils and macrophages from ex vivo-cultured murine bone marrow for morphologic maturation and functional responses by imaging flow cytometry.
Topics: Animals; Bone Marrow Cells; Calcimycin; Cell Differentiation; Cryopreservation; Extracellular Traps; Flow Cytometry; Fluorescent Dyes; Image Cytometry; Immunity, Innate; Macrophages; Male; Mice; Mice, Inbred C57BL; Neutrophils; Phagocytosis; Primary Cell Culture; Staining and Labeling; Tetradecanoylphorbol Acetate | 2017 |
Xinqin exhibits the anti-allergic effect through the JAK2/STAT5 signaling pathway.
Topics: Animals; Anti-Allergic Agents; Calcimycin; Cell Degranulation; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Drugs, Chinese Herbal; Guinea Pigs; Histamine; Humans; Immunoglobulin E; Interleukin-6; Janus Kinase 2; Leukotriene D4; Male; Mast Cells; Phosphorylation; Rhinitis, Allergic; Signal Transduction; STAT5 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Tetradecanoylphorbol Acetate; Toluene 2,4-Diisocyanate; Tumor Necrosis Factor-alpha | 2016 |
Novel Insights in the Regulation of Phosphatidylserine Exposure in Human Red Blood Cells.
Topics: Annexin A5; Benzophenanthridines; Calcimycin; Calcium; Cells, Cultured; Charybdotoxin; Erythrocyte Count; Erythrocytes; Gene Expression Regulation; Humans; Intermediate-Conductance Calcium-Activated Potassium Channels; Lysophospholipids; Methomyl; Naphthalenes; Phosphatidylserines; Phospholipid Transfer Proteins; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate | 2016 |
Diverse stimuli engage different neutrophil extracellular trap pathways.
Topics: Calcimycin; Candida albicans; Extracellular Traps; Granulomatous Disease, Chronic; Healthy Volunteers; Humans; Metabolic Networks and Pathways; Neutrophils; Nigericin; Streptococcus; Tetradecanoylphorbol Acetate | 2017 |
Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT), an anticancer agent, exerts an anti-inflammatory effect in activated human mast cells.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Calcimycin; Caspase Inhibitors; Cell Line; Cytokines; Humans; Hypoxia-Inducible Factor 1; Ionophores; MAP Kinase Signaling System; Mast Cells; NF-kappa B; RNA, Messenger; Tetradecanoylphorbol Acetate; Thiosemicarbazones; Thymic Stromal Lymphopoietin; Vascular Endothelial Growth Factor A | 2017 |
MAPKs and NF‑κB pathway inhibitory effect of bisdemethoxycurcumin on phorbol‑12‑myristate‑13‑acetate and A23187‑induced inflammation in human mast cells.
Topics: Calcimycin; Cell Line; Curcumin; Diarylheptanoids; Gene Expression Regulation; Humans; Inflammation; Mast Cells; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2018 |
Fisetin inhibits IL-31 production in stimulated human mast cells: Possibilities of fisetin being exploited to treat histamine-independent pruritus.
Topics: Animals; Calcimycin; Cell Line; Flavonoids; Flavonols; Histamine Release; Humans; Interleukins; MAP Kinase Signaling System; Mast Cells; Mice; Mice, Inbred ICR; Pruritus; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate | 2018 |
MiR-302e attenuates allergic inflammation
Topics: Calcimycin; Cell Line; Gene Expression Regulation; Humans; Inflammation; Mast Cells; MicroRNAs; NF-kappa B; Ovalbumin; Rhinitis, Allergic; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2018 |
Geraniol suppresses proinflammatory mediators in phorbol 12-myristate 13-acetate with A23187-induced HMC-1 cells.
Topics: Acyclic Monoterpenes; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Cell Line; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Histamine; Humans; Inflammation Mediators; Mice; Mice, Inbred BALB C; Molecular Structure; Ovalbumin; Rhinitis, Allergic; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate | 2018 |
hsa-miR-20a-5p attenuates allergic inflammation in HMC-1 cells by targeting HDAC4.
Topics: Base Sequence; Calcimycin; Cell Line; Cytokines; Down-Regulation; Epigenesis, Genetic; Histone Deacetylases; Humans; Hypersensitivity; Inflammation; Inflammation Mediators; MicroRNAs; Ovalbumin; Repressor Proteins; Tetradecanoylphorbol Acetate | 2019 |
Neutrophil extracellular traps (NET) induced by different stimuli: A comparative proteomic analysis.
Topics: Autoantibodies; Autoimmune Diseases; Calcimycin; Chromatin; Cluster Analysis; Escherichia coli; Extracellular Traps; Gene Ontology; Histones; Humans; Lipopolysaccharides; Neutrophils; Peroxidase; Protein Processing, Post-Translational; Proteomics; Tetradecanoylphorbol Acetate | 2019 |
Xanthone suppresses allergic contact dermatitis in vitro and in vivo.
Topics: Administration, Oral; Anaphylaxis; Animals; Anti-Allergic Agents; Calcimycin; Cell Line; Dermatitis, Allergic Contact; Dinitrofluorobenzene; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Inflammation Mediators; Keratinocytes; Male; Mast Cells; Mice; Mitogen-Activated Protein Kinases; p-Methoxy-N-methylphenethylamine; Phosphorylation; Skin; Tetradecanoylphorbol Acetate; Xanthones | 2020 |
Tripterine: A Potential Anti-Allergic Compound.
Topics: Anaphylaxis; Animals; Anti-Allergic Agents; Calcimycin; Cytokines; Disease Models, Animal; Drugs, Chinese Herbal; Histamine Release; Humans; Male; Mast Cells; Mice, Inbred BALB C; NF-kappa B; p-Methoxy-N-methylphenethylamine; Pentacyclic Triterpenes; Rats; Rhinitis, Allergic; Tetradecanoylphorbol Acetate; Triterpenes | 2021 |
In vivo and in vitro anti‑allergic and anti‑inflammatory effects of Dryopteris crassirhizoma through the modulation of the NF‑ĸB signaling pathway in an ovalbumin‑induced allergic asthma mouse model.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Calcimycin; Cell Line, Tumor; Cytokines; Disease Models, Animal; Dryopteris; Humans; Lung; Male; Mast Cells; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Phytotherapy; Plant Extracts; Signal Transduction; Tetradecanoylphorbol Acetate | 2020 |
Chloroquine attenuates thymic stromal lymphopoietin production via suppressing caspase-1 signaling in mast cells.
Topics: Animals; Calcimycin; Caspase 1; Caspase Inhibitors; Cell Line; Chloroquine; Cytokines; Ear Diseases; Edema; Humans; Male; MAP Kinase Signaling System; Mast Cells; Mice; Mice, Inbred ICR; NF-kappa B; RNA, Messenger; Signal Transduction; Stromal Cells; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Thymus Gland | 2021 |
Morphology of Neutrophils during Their Activation and NETosis: Atomic Force Microscopy Study.
Topics: Calcimycin; Cell Nucleus; Extracellular Traps; Microscopy, Atomic Force; Neutrophils; Tetradecanoylphorbol Acetate | 2023 |