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tetradecanoylphorbol acetate and bisindolylmaleimide i

tetradecanoylphorbol acetate has been researched along with bisindolylmaleimide i in 294 studies

Research

Studies (294)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's125 (42.52)18.2507
2000's150 (51.02)29.6817
2010's19 (6.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alcami, J; Bessia, C; Hay, RT; Paya, CV; Ten, RM; Virelizier, JL1
Imre, K; Jacobson, PB; Kuchera, SL; Metz, A; Schächtele, C; Schrier, DJ1
Loh, TT; Zhu, WH1
Falet, H; Rendu, F1
Corvol, M; Friedlander, G; Garabédian, M; Menaa, C; Vrtovsnik, F1
Baldo, A; Cianflone, K; Sniderman, AD; St Luce, S; Zhang, XJ1
King, GL; Kramer, RM; Xia, P1
Cox, AJ; Lee, RK; Nitsch, RM; Wurtman, RJ1
Ausiello, DA; Breuer, W; Cabantchik, IZ; Glickstein, H; Kartner, N; Riordan, JR1
Hori, M; Itoh, T; Iwakura, K; Kitakaze, M; Komamura, K; Minamino, T; Morioka, T; Node, K; Okazaki, Y; Takashima, S1
Laughlin, KV; Marano, CW; Mullin, JM; Russo, LM1
Araki, R; Komada, T; Naka, M; Nakatani, K; Shima, T; Tanaka, T1
Chan, KF; Loh, TT; Lok, CN1
Deli, E; Kiss, Z1
Brass, LF; Hagège, J; He, CJ; Rondeau, E; Sraer, JD; Xu, Y; Zacharias, U1
Anderson, WH; Kiss, Z; Phillips, H1
Bouchard, B; Coulomb, B; Dubertret, L; Le Panse, R; Lebreton, C; Mitev, V1
Leslie, CC; Qiu, ZH1
Finkenzeller, G; Häussinger, D; Lang, F; Newsome, W1
Dautrevaux, M; Formstecher, P; Lefebvre, P; Tahayato, A1
Bi, N; Mamrack, MD1
Brecha, N; Corey, JL; Davidson, N; Lester, HA; Quick, MW1
Schächtele, C; Seifert, R; Wenzel-Seifert, K1
Dwyer, LD; Jaken, S; Malkinson, AM; Miller, AC; Parks, AL1
Burn, P; Camoin, L; Fagard, R; Fischer, S; Guillaume, JL; Meggio, F; Rothhut, B; Soula, M; Strosberg, D; Vorherr, T1
Barth, H; Jacobson, P; Kuchera, S; Metz, A; Schaechtele, C; Schrier, D1
Bonev, AD; Nelson, MT1
Eriksson, K; Heikkilä, J; Jalava, A1
Ben-Av, P; Eli, Y; Liscovitch, M; Schmidt, US; Tobias, KE1
Blumberg, PM; Goodnight, JA; Kazanietz, MG; Kolch, W; Martiny-Baron, G; Mischak, H; Mushinski, JF; Pierce, JH; Schaechtle, C1
Dadgar, J; Hundle, B; McMahon, T; Messing, RO1
Erusalimsky, JD; Hong, Y; Martin, JF; Vainchenker, W1
Haimovich, B; Ji, P; Kaneshiki, N1
Bhatia, M; Kirkland, JB; Meckling-Gill, KA1
Carey, JO; deVente, JE; Pettit, GR; Posekany, KJ; Ways, DK1
Alexandrov, IA; Hilbert, DM; Mushinski, JF; Nordan, RP; Romanova, LY; Schwab, G1
Bouchard, B; Coulomb, B; Le Panse, R; Lebreton, C1
Granot, Y; Isakov, N; Tamir, A1
Fagerström, S; Gestblom, C; Nånberg, E; Påhlman, S1
Carpentier, G; Lagord, C; Leibovitch, MP; Leibovitch, SA; Martelly, I1
Kurata, S; Matsumoto, M; Nakajima, H1
Kiss, Z1
Gercken, G; Radloff, M1
Driessens, MH; Roos, E; Soede, RD; van Hulten, PE; van Rijthoven, EA1
Dubois, T; Geny, B; Lukowski, S; Mira, JP; Oudinet, JP; Russo-Marie, F1
Hakeda, Y; Kameda, T; Kumegawa, M; Mano, H; Raisz, LG; Shiokawa, M1
Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Minamino, T; Node, K; Tada, M1
Evans, R; Fuller, JA; Kamdar, SJ1
Classen, S; Eissner, G; Fichter, M; Hinrichs, R; Scheffer, B; Ueffing, M1
Benna, JE; Dang, PM; Fay, M; Gaudry, M; Gougerot-Pocidalo, MA; Hakim, J; Morel, F1
Ferrante, A; Hii, CS; Huang, ZH; Murray, AW; Poulos, A; Rathjen, DA1
Fukuda, K; Kato, S; Mori, K; Morikawa, H; Shoda, T1
Hakeda, Y; Hanada, K; Kakudo, S; Kameda, T; Kumegawa, M; Mano, H; Miyazawa, K; Mori, Y; Nakamaru, Y; Shiokawa-Sawada, M; Yuasa, T1
Courage, C; Gescher, A; Hubbard, A; Jones, T1
Boucheix, C; Francastel, C; Lantz, O; Le Naour, F; Prenant, M; Rubinstein, E1
Jorcano, JL; Paramio, JM1
Evans, R; Fuller, JA; Kamdar, SJ; Nishikawa, SI1
Cox, ME; Parsons, SJ1
Brunet, C; Cabanis, A; Cazin, JC; Cazin, M; Dine, T; Gressier, B; Luyckx, M1
Byers, SW; Crockett, C; Jensen, JP; Orford, K; Weissman, AM1
Häussinger, D; Kurz, AK; Schliess, F; vom Dahl, S1
Gilad, E; Matzkin, H; Zisapel, N1
Funaya, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Node, K; Okuyama, Y; Sato, H; Ueda, Y; Yoshida, K1
Acs, P; Bíró, T; Blumberg, PM; Bögi, K; Lorenzo, PS; Marquez, AM; Mushinski, JF; Szállási, Z; Wang, QJ1
Stepan, VM; Takeuchi, Y; Todisco, A; Urumov, A; Yamada, J; Yamada, T1
García, LJ; González, A; Jensen, RT; Rosado, JA1
Jensen, RT; Kusui, T; Tsuda, T1
Almazan, G; Larocca, JN1
Liu, J; Marcus, DC; Scofield, MA; Shen, Z; Sunose, H1
Chang, WC; Chen, BK; Liaw, YW; Liu, YW1
Friedman, LM; Lazarovici, P; Matsuda, Y1
Kucera, GL; Stadheim, TA1
Gohda, E; Iwao, M; Okauchi, H; Yamamoto, I1
Alexandrov, IA; Blagosklonny, MV; Mushinski, JF; Nordan, RP; Romanova, LY1
de Jonge, HR; Dorrestijn, J; Maassen, JA; Narumiya, S; Tilly, BC; van der Wijk, T1
Aaronson, DS; Crespo, P; Font de Mora, J; Gutkind, JS; Santos, E1
Alameda, F; Batlle, E; de Herreros, AG; del Mont Llosas, M; Díaz, V; Domínguez, D; Loukili, N; Paciucci, R; Verdú, J1
Amar, LS; Forest, N; Martin, N; Oboeuf, M1
Chow, SC; Jondal, M; Osorio, LM; Rottenberg, M1
Bond, JA; Dawson, TP; Eccles, NG; Gescher, A; Hall-Jackson, CA; Jones, T; Wynford-Thomas, D1
Andersson, G; Onyango, I; Pihlgren, U; Rask, L; Setterblad, N1
Kobayashi, M; Kuroda, A; Maruyama, M; Mino, T; Sugiyama, E; Taki, H; Yamashita, N1
Costa, LG; Guizzetti, M; Wei, M1
Nagarkatti, DS; Sha'afi, RI1
Fukunaga, T; Ishibashi, S; Nigorikawa, K; Okamura, N; Yaname, H1
Conn, PM; Lin, X1
Albright, JA; Kolomytkin, OV; Marino, AA; Sadasivan, KK; Wolf, RE1
Blank, U; David, B; Guérin-Marchand, C; Iannascoli, B; Marchand, F; Pelletier, C; Weyer, A1
Hayashi, R; Kobayashi, M; Maruyama, M; Matsui, S; Sugiyama, E; Sugiyama, S; Yamashita, N1
Guo, YL; Kang, B; Williamson, JR1
Aboud, M; Mor-Vaknin, N; Torgeman, A1
Barboule, N; Chadebech, P; Lafon, C; Valette, A; Vidal, S1
Lan, L; Wong, NS1
Brown, JF; Chang, Q; Soper, BD; Tepperman, BL1
Abe, N; Habu, S; Iwakabe, K; Kitamura, H; Matsuki, N; Nakui, M; Nishimura, T; Ohmi, Y; Ohta, A; Sato, M; Yagita, H; Yahata, C; Yahata, T1
Bissonnette, M; Brasitus, TA; Khare, S; Scaglione-Sewell, B; Sitrin, MD; Wali, RK1
Acs, P; Alexandrov, IA; Blagosklonny, MV; Blumberg, PM; Garfield, S; Mushinski, JF; Nguyen, P; Nordan, RP; Romanova, LY; Trepel, J1
Conn, PM; Han, XB1
Shibuya, M; Takahashi, T; Ueno, H1
Oldenborg, PA; Sehlin, J1
Nishioka, M; Okumura, K; Sasazuki, T; Shirasawa, S1
Akasaki, T; Koga, H; Sumimoto, H1
Akiba, S; Hayama, M; Kume, K; Mizunaga, S; Sato, T1
Christoffersen, T; Dajani, OF; Melien, O; Nilssen, LS; Rezvani, F; Sandnes, D; Thoresen, GH1
Brass, LF; Cichowski, K; Orsini, MJ1
Barańska, J; Czajkowski, R1
Boland, RL; Capiati, DA; Limbozzi, F; Téllez-Iñón, MT1
Backendorf, C; Borgstein, AM; Medema, JP; Sark, MW; van de Putte, P1
Amar, LS; Forest, N; Martin, N; Oboeuf, M; Shabana, AH1
Anema, SM; Arthur, JR; Beckett, GJ; Howie, AF; Nicol, F; Walker, SW1
Leupen, SM; Levine, JE1
Akamatsu, N; Higaki, T; Imamura, H; Komatsu, S; Kono, Y; Nakagawa, M; Sato, T; Sawada, S; Tada, Y; Tamagaki, T; Toratani, A; Tsuda, Y; Tsuji, H; Yamasaki, S1
Karnes, WE; Klein, IK; Penington, RC; Weller, SG1
Libermann, TA; Petersen, N; Prinz, S; Sallmann, S; Schneider, A; Schwaninger, M; Spranger, M1
Ferris, HA; García, LJ; Jensen, RT; Tapia, JA1
Becker, K; Brodde, OE; Heinroth-Hoffmann, I; Osten, B; Pönicke, K1
Palmer, TM; Stiles, GL1
Barnes, PJ; Giembycz, MA; Hellewell, PG; Lindsay, MA; Lynch, OT1
Chang, Q; Soper, BD; Tepperman, BL2
Behrens, MM; Choi, DW; Gwag, BJ; Koh, JY; Strasser, U1
Hamad, AM; Knox, AJ1
Gear, AR; Polanowska-Grabowska, R1
Becker, M; Cato, AC; Klocker, H; Mink, S; Peterziel, H; Schonert, A1
Farokhzad, OC; Hrnjez, BJ; Matthews, JB; Song, JC1
Alessi, DR; Fahlman, R; Krook, A; Ryder, JW; Wallberg-Henriksson, H; Zierath, JR1
Costa, LG; Guizzetti, M; Wei, M; Yost, M1
Cafferata, EG; Giordano, L; González-Guerrico, AM; Pivetta, OH; Santa-Coloma, TA1
Chiu, CT; Huang, SC; Lin, CC; Pan, SL; Tsai, YJ; Wang, CC; Wu, WB; Yang, CM1
Han, B; Logsdon, CD1
Bourgeade, MF; Cayre, YE; Thang, MN; Ye, F1
Chen, Y; Deng, J; Wu, R1
Slack, BE1
Bao, HF; Eaton, DC; Malik, B; Middleton, P; Schenck, J; Schlanger, LE; Stockand, JD1
Tai, HH; Tong, M1
Chaudhuri, S; Raha, S1
Aquino, A; Barrera, G; Dianzani, MU; Farace, MG; Fazio, VM; Pizzimenti, S; Rinaldi, M; Spinsanti, P1
Kapfhammer, JP; Metzger, F1
Dunzendorfer, S; Wiedermann, CJ1
Barańska, J; Bobeszko, M; Dygas, A; Nalepa, I1
Bao, HF; Eaton, DC; Edinger, RS; Johnson, JP; Yue, G1
Almas, J; Rubin, E; Solem, M; Thomas, A1
Auberger, P; Baier, G; Bertolotto, C; Filippa, N; Maulon, L1
Fujimoto, S; Hayakawa, T; Kawakami, N; Kita, K; Yamaguchi, T1
Chae, SW; Cho, CH; Jo, SH; Lee, CO1
Bruni, P; Cencetti, F; Donati, C; Meacci, E; Romiti, E1
Cunningham, FM; Goode, NT; Greenaway, EC1
Brodbeck, K; Häring, HU; Pfeiffer, A; Sauer, U; Schleicher, ED; Weigert, C1
Aoki, T; Etoh, T; Hashimoto, T; Imamura, M; Inoguchi, T; Kakimoto, M; Li, P; Naruse, M; Nawata, H; Sano, H; Umeda, F; Utsumi, H; Yu, HY1
Hasse, A; Kuger, P; Meyer-Kirchrath, J; Nilius, SM; Schrör, K1
Doggett, TA; Lemker, JL; Partridge, NC; Swarthout, JT1
Aguilera, J; Gil, C; Najib, A; Pelliccioni, P1
Meinhardt, G; Roth, J; Totok, G1
Courtois, G; Kuiperij, HB; van der Eb, AJ; Vertegaal, AC; Yamaoka, S; Zantema, A1
Jang, MA; Kwon, TK; Lee, YH; Park, JW; Passaniti, A1
Wenner, CE; Yan, S1
Kaneda, N; Murata, T; Niimi, Y1
Boland, R; Buitrago, C; de Boland, AR; Morelli, S1
Giardina, JB; Khalil, RA; Tanner, DJ1
Akimoto, K; Hattori, Y; Kakishita, H; Kasai, K; Matsumura, M1
Grant, S; Vrana, JA1
Bauer, CK; Schledermann, W; Schwarz, JR; Wulfsen, I1
Aizawa, T; Hashizume, K; Ikeo, S; Nakajima, K; Shigematsu, S; Yamauchi, K1
Hashimoto, M; Hsu, L; Mallory, M; Masliah, E; Rockenstein, E1
Banan, A; Fields, JZ; Keshavarzian, A; Zhang, Y1
Hamada, H; Shimizu, T; Sugibayashi, R; Suzuki, T; Takeda, K; Yamamoto, N1
Massoumi, R; Sjölander, A1
Avruch, J; Gonçalves, D; Lenz, G; Luo, Z; Neary, JT; Rodnight, R1
Haye, B; Huet, E; Legue, O; Martiny, L; Petitfrère, E; Sartelet, H1
Hashimoto, T; Imamura, M; Inoguchi, T; Kakimoto, M; Nakashima, N; Nawata, H; Umeda, F; Yu, HY1
Kanda, Y; Kuroki, Y; Mizuno, K; Nishio, E; Watanabe, Y1
Chaby, R; Girard, R; Pédron, T1
Chen, JS; Song, JG1
Chibalin, AV; Féraille, E; Kovalenko, MV; Ryder, JW; Wallberg-Henriksson, H; Zierath, JR1
Crow, T; Neary, JT; Siddiqi, V; Xue-Bian, JJ1
Cruciani, V; Husøy, T; Mikalsen, SO1
Costa, LG; Guizzetti, M; Lu, H1
Gant, TW; Gescher, A; Gill, PK1
Matthews, JB; Mun, EC; Nichols, A; Song, JC; Yoo, J1
Higashi, T; Horiuchi, H; Kita, T; Nishioka, H; Ozaki, H; Shirakawa, R; Tabuchi, A; Yamamoto, A; Yoshioka, A1
Andreeva, AY; Blasig, IE; Krause, E; Müller, EC; Utepbergenov, DI1
Låg, M; Refsnes, M; Schwarze, PE; Thoresen, GH; Thrane, EV1
Denys, A; Hichami, A; Khan, NA; Maume, B1
Bayguinov, O; Hagen, B; Kenyon, JL; Sanders, KM1
Hur, SY; Ki, IK; Kim, JW; Kim, TE; Kim, YW; Lee, JM; Namkoong, SE1
Frey, BM; Frey, FJ; Heiniger, CD; Rochat, MK1
Kwak, JY; Lee, MJ; Oh, JY; Park, HT; Uhlinger, DJ1
Cho, W; Han, JM; Jung, YW; Kim, JH; Kim, Y; Kuroki, T; Lee, BD; Lee, S; Lee, SD; Ohba, M; Ryu, SH; Suh, PG1
Hung, AC; Sun, SH1
Chandrasekhar, S; Halladay, D; Martin, TJ; Onyia, JE; Yang, X1
Bander, E; Faragó, A; Sipeki, S; Ways, DK1
Fujitani, Y; Gorogawa, S; Hori, M; Kajimoto, Y; Kawamori, D; Kuroda, A; Ohtoshi, K; Umayahara, Y; Yamasaki, Y; Yasuda, T; Yoshida, S1
Surmacz, L; Wiejak, J; Wyroba, E1
Barritault, D; Crépin, M; Ledoux, D; Liu, JF; Liu, JM1
Auberger, P; Bottero, V; Busuttil, V; Frelin, C; Imbert, V; Peyron, JF; Ricci, JE1
Baker, HW; Dunlop, ME; Garrett, C; Grkovic, I; Liu, DY; Martic, M1
Joseph, SR; Le, TL; Stow, JL; Yap, AS1
Fukuta, H; Kito, Y; Suzuki, H; Yamamoto, Y1
Bragado, MJ; García-Marin, LJ; Jensen, RT; Pace, A; Tapia, JA1
Banerji, L; Glassford, J; Holman, M; Kadowaki, T; Klaus, GG; Koyasu, S; Lam, EW; Skarell, SM; Soeiro, I1
Bacon, BR; Britton, RS; Li, L; O'Neill, R; Ramm, GA1
Bhugra, P; Dhalla, NS; Rathi, S; Xu, YJ1
Briaud, I; Dickson, LM; Lingohr, MK; Rhodes, CJ; Wrede, CE1
Cruciani, V; Leithe, E; Mikalsen, SO; Rivedal, E; Sanner, T1
Cohen, GM; Farrow, SN; Harper, N; Hughes, MA; MacFarlane, M1
Chain, BM; Cho, JY; Katz, DR1
Alemany, S; Caivano, M; Cohen, P; Rodriguez, C1
Chang, YY; Sun, SH; Wang, CM1
Charkaoui-Malki, M; Cherkaoui-Malki, M; Hichami, A; Khan, NA; Madani, S1
Dutta, S; Häussinger, D; Kubitz, R; Kühlkamp, T; Saha, N; vom Dahl, S; Wettstein, M1
Ding, L; Lang, W; Wang, H; Xiao, L1
Chen, JS; Exton, JH1
Ajioka, H; Akizawa, Y; Kanda, A; Kiniwa, M; Matsuura, N; Nakano, M; Nishihara, K; Nozawa, Y; Orimoto, N; Uji, T1
Chang, KC; Kang, YJ; Kim, HJ; Ko, YS; Lee, YS; Park, MK; Pyo, HS; Seo, HG; Yun-Choi, HS1
Eppig, JJ; O'brien, M; Viveiros, MM1
Cho, YW; Hahm, ET; Lee, JJ; Min, BI1
Jiménez, E; Montiel, M; Quesada, J1
Burrin, JM; Fowkes, RC; Grossman, AB; Khalaf, S; Korbonits, M; Mozid, AM; Nanzer, AM; Patel, MV1
Daosukho, C; Kiningham, KK; St Clair, DK1
Brodie, C; Cohen, A; Deutsch, E; Dovrat, S; Kazimirsky, G; Rubinfeld, H; Sarid, R1
Chen, PW; Kroog, GS1
Bristulf, J; Owman, C; Sabirsh, A1
Imamura, T; Ishisaki, A; Nakajima, K; Tsunobuchi, H1
Branchi, I; Capone, F; Costa, LG; Fattori, V; Giordano, G; Madia, F; Vitalone, A1
Closs, EI; Martiné, U; Rotmann, A; Strand, D1
Alviña, K; Boric, MP; Figueroa, XF; Garcés, G; Martínez, AD; Rosemblatt, M; Sáez, JC1
Leithe, E; Rivedal, E1
Gylfe, E; Rask, L; Sakwe, AM1
Madras, BK; Miller, GM; Yatin, SM1
Camden, JM; Camden, RE; Erb, L; González, FA; Schrader, AM; Seye, CI; Weisman, GA1
Kuan, YH; Lin, CN; Lin, RH; Tsao, LT; Wang, JP1
Cameron, P; Kanke, T; Macfarlane, SR; McKenzie, RC; Plevin, R; Sloss, CM1
Barnes-Davies, M; Bhattacharjee, A; Forsythe, ID; Hamann, M; Kaczmarek, LK; Oliver, DL; Song, P; Yang, Y1
Gerlo, S; Kooijman, R; Verdood, P1
Hu, N; Li, L; Sampat, K; Yuspa, SH; Zakari, J1
Clerk, A; Markou, T; Sugden, PH; Yong, CS1
Fujii, T; Fukushima, S; Kaneyuki, U; Kato, S; Kazanietz, MG; Maeda, M; Oshima, K; Shigemori, M1
Gosens, R; Grootte Bromhaar, MM; Maarsingh, H; Meurs, H; Nelemans, SA; ten Damme, A; Zaagsma, J1
Auersperg, N; Choi, KC; Kim, KY; Leung, PC1
Cho, NJ; Cho, TJ; Park, YS1
Akopian, A; Cristofanilli, M1
Doi, SQ; Glerum, S; Mendonça, MC; Sellitti, DF1
Linsdell, P; McDonald, TF; Missan, S1
Hayashi, H; Kondo, T; Suzuki, S; Takagi, K; Ueyama, J; Wakusawa, S1
Adrian, TE; Bell, RH; Ding, XZ; Flesche, JB; Robin, TP; Salabat, MR; Talamonti, MS; Ujiki, MB1
Aguilar, R; Bellido, C; Garrido-Gracia, JC; Sánchez-Criado, JE1
Fujino, H; Hirabayashi, T; Murayama, T; Nakamura, H; Shimizu, M; Taniguchi, T1
Di Jeso, B; Elia, MG; Marsigliante, S; Muscella, A; Storelli, C; Treglia, AS; Ulianich, L1
Chang, HC; Chen, IS; Cheng, HH; Chi, CC; Chu, ST; Ho, CM; Hsu, SS; Huang, CJ; Huang, JK; Jan, CR; Liu, SI; Lu, YC; Su, HH; Wang, JL1
Hara, A; Hirade, K; Hotta, K; Ito, H; Kato, K; Kozawa, O; Niwa, M1
Burek, CL; Sharma, RB; Traore, K; Trush, MA1
Bollinger, J; Cherny, VV; DeCoursey, TE; Finnegan, A; Gelb, MH; Morgan, D1
Abe, K; Nishiura, T1
Ding, WG; Horie, M; Ito, M; Matsuura, H; Toda, H; Toyoda, F; Yasuda, Y1
Cockerill, SL; Mitcheson, JS; Standen, NB; Tobin, AB; Torrecilla, I; Willars, GB1
Carlson, AE; Franceschi, RT; Gopalakrishnan, R; Suttamanatwong, S1
Chou, CC; Hsu, CY; Yung, BY1
Eggo, MC; Susarla, R; Watkinson, JC1
Bond, JA; Errington, R; Gescher, AJ; Lemoine, NR; Smith, PJ; Verschoyle, RD; Wiltshire, M; Wynford-Thomas, D1
Gergely, P; Kovács, I; Sipka, S; Szíjgyártó, Z; Szucs, K; Zákány, R1
D'Souza, T; Indig, FE; Morin, PJ1
Beltran, L; Digiovanni, J; Lu, J; Rho, O; Wilker, E1
Bocking, AD; Casciani, V; Challis, JR; Di Iorio, R; Marinoni, E; Moscarini, M1
Chen, P; Soo, J; Xue, R; Zhang, E1
Hanai, Y; Kozawa, O; Matsushima-Nishiwaki, R; Minamitani, C; Otsuka, T; Takai, S; Tokuda, H1
Aherne, SA; O'Brien, NM1
Arakawa, Y; Tomimatsu, N1
O'Sullivan, AW; Redmond, HP; Wang, JH1
Grichtchenko, II; Perry, C; Quissell, DO; Reyland, ME1
Pan, L; Song, K; Wu, X; Xu, J; Zhang, X1
Stricker, SA1
Chacko, S; Chang, S; Hypolite, JA; Mohanan, S; Wein, AJ; Zderic, SA1
Alrefai, WA; Annaba, F; Dwivedi, A; Gill, RK; Saksena, S; Sarwar, Z1
Ballim, RD; Mowla, S; Prince, S; Teng, H1
Boehm, S; Drobny, H; Kosenburger, K; Schicker, KW1
Bhamrah, M; Capasso, M; Cherny, VV; DeCoursey, TE; Dyer, MJ; Morgan, D; Musset, B1
Hu, T; Liu, Z; Shen, X1
Li, ZQ; Song, L; Yang, P; Yin, YQ1
Ali-Osman, F; Okamura, T; Singh, S1
Ceballos, NR; Volonteri, MC1
Hirata, K; Imamura, M; Ito, T; Kimura, Y; Kojima, T; Kyuno, D; Murata, M; Sawada, N; Takasawa, A; Tanaka, S; Yamaguchi, H1
Fukayama, M; Fukushima, N; Ishikawa, S; Kokudo, N; Shibahara, J; Shinozaki, A; Tanaka, M; Umeda, M1
Benjamin, A; Orogo-Wenn, M; Soukup, B; Walters, D1
Adachi, T; Hara, H; Kamiya, T; Makino, J1
Dai, Y; Kobayashi, K; Kogure, Y; Noguchi, K; Wan, Y; Wang, S; Yamanaka, H; Zhang, W; Zhu, W1
Jensen, RT; Nuche-Berenguer, B; Sancho, V1
Song, N; Wang, J; Wang, W; Xie, J; Zhang, H1
Chao, CY; Chen, HW; Li, CC; Lii, CK; Lin, LL; Liu, KL; Lu, CY1
Furue, MK; Hirata, M; Hirayama, N; Kawamura, S; Kinehara, M; Kohara, A; Matsumura, H; Mimura, S; Suga, M; Tateyama, D; Uchio-Yamada, K; Yanagihara, K1
Reetz, O; Strauss, U1
Chang, HT; Chen, FA; Cheng, HH; Cheng, JS; Chou, CT; Jan, CR; Kuo, CC; Kuo, DH; Liang, WZ; Shieh, P; Sun, TK; Tseng, HW1
Nazıroğlu, M1
Bhattacharya, S; Bible, PW; Cataisson, C; Gormley, AC; Kellett, MD; Morasso, MI; Palazzo, E; Sun, HW; Yuspa, SH1
Geng, Y; He, C; Li, L; Li, Y; Liang, X; Ma, Y; Shu, G; Song, X; Ye, G; Yin, L; Yin, Z; Yue, G; Zhang, R; Zhao, Y; Zou, Y1

Other Studies

294 other study(ies) available for tetradecanoylphorbol acetate and bisindolylmaleimide i

ArticleYear
NF-kappa B-dependent induction of the NF-kappa B p50 subunit gene promoter underlies self-perpetuation of human immunodeficiency virus transcription in monocytic cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Aug-15, Volume: 89, Issue:16

    Topics: Base Sequence; Binding Sites; Cell Line; Cell Nucleus; Cytoplasm; Enhancer Elements, Genetic; HIV Long Terminal Repeat; HIV-1; Humans; Indoles; Isoenzymes; Macromolecular Substances; Maleimides; Molecular Sequence Data; Monocytes; NF-kappa B; Oligonucleotide Probes; Promoter Regions, Genetic; Protein Kinase C; Tetradecanoylphorbol Acetate; Transcription, Genetic; Virus Replication

1992
Anti-inflammatory properties of Gö 6850: a selective inhibitor of protein kinase C.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 275, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Dinoprostone; Enzyme Inhibitors; Female; Hypersensitivity, Delayed; Indoles; Macrophages, Peritoneal; Maleimides; Mice; Mice, Inbred BALB C; Neutrophils; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate

1995
Effects of Na+/H+ antiport and intracellular pH in the regulation of HL-60 cell apoptosis.
    Biochimica et biophysica acta, 1995, Nov-09, Volume: 1269, Issue:2

    Topics: Amiloride; Apoptosis; DNA Damage; Enzyme Inhibitors; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Indoles; Ionophores; Maleimides; Monensin; Protein Kinase C; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate

1995
Calcium mobilisation controls tyrosine protein phosphorylation independently of the activation of protein kinase C in human platelets.
    FEBS letters, 1994, May-23, Volume: 345, Issue:1

    Topics: Blood Platelets; Calcium; Edetic Acid; Enzyme Activation; Humans; Indoles; Maleimides; Phosphorylation; Phosphotyrosine; Platelet Activation; Platelet Aggregation; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Tyrosine

1994
Insulin-like growth factor I, a unique calcium-dependent stimulator of 1,25-dihydroxyvitamin D3 production. Studies in cultured mouse kidney cells.
    The Journal of biological chemistry, 1995, Oct-27, Volume: 270, Issue:43

    Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Binding, Competitive; Biological Transport; Calcitriol; Calcium; Calcium Channel Blockers; Cells, Cultured; Cycloheximide; Enzyme Inhibitors; Humans; Indoles; Insulin; Insulin-Like Growth Factor I; Kidney Tubules, Proximal; Male; Maleimides; Mice; Phosphates; Protein Kinase C; Protein Synthesis Inhibitors; Receptors, Calcitriol; Sodium; Tetradecanoylphorbol Acetate; Verapamil

1995
Signal transduction pathway of acylation stimulating protein: involvement of protein kinase C.
    Journal of lipid research, 1995, Volume: 36, Issue:7

    Topics: Blood Proteins; Cells, Cultured; Complement C3a; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Humans; Indoles; Maleimides; Naphthalenes; Protein Kinase C; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Triglycerides

1995
Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:2

    Topics: Animals; Arachidonic Acids; Biological Transport, Active; Cattle; Cells, Cultured; Cytosol; Enzyme Activation; Glucose; Humans; Hyperglycemia; Indoles; Maleimides; Muscle, Smooth, Vascular; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Rubidium; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate

1995
Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Aug-15, Volume: 92, Issue:17

    Topics: Alanine; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line; Chelating Agents; Cycloleucine; Embryo, Mammalian; Fetus; Glioma; Glutamic Acid; Hippocampus; Humans; Indoles; Kidney; Kinetics; Maleimides; N-Methylaspartate; Neuroblastoma; Neurons; Neurotoxins; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Protein Processing, Post-Translational; Pyrimidines; Quinacrine; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1995
Protein kinase C mediates down-regulation of cystic fibrosis transmembrane conductance regulator levels in epithelial cells.
    The Journal of biological chemistry, 1993, Jul-05, Volume: 268, Issue:19

    Topics: Adenocarcinoma; Colonic Neoplasms; Cycloheximide; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dactinomycin; Epithelium; Gene Expression Regulation, Neoplastic; Humans; Indoles; Maleimides; Membrane Proteins; Pancreatic Neoplasms; Protein Biosynthesis; Protein Kinase C; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1993
Alpha 1-adrenoceptor activation increases ecto-5'-nucleotidase activity and adenosine release in rat cardiomyocytes by activating protein kinase C.
    Circulation, 1995, Apr-15, Volume: 91, Issue:8

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; In Vitro Techniques; Indoles; Male; Maleimides; Methoxamine; Myocardium; Norepinephrine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate

1995
The protein kinase C inhibitor, bisindolylmaleimide, inhibits the TPA-induced but not the TNF-induced increase in LLC-PK1 transepithelial permeability.
    Biochemical and biophysical research communications, 1995, Apr-17, Volume: 209, Issue:2

    Topics: Animals; Epithelium; In Vitro Techniques; Indoles; LLC-PK1 Cells; Maleimides; Permeability; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1995
Protein kinase C-independent activation of Raf-1 and mitogen-activated protein kinase by leukotriene B4 in guinea pig eosinophils.
    Biochemical and biophysical research communications, 1995, May-25, Volume: 210, Issue:3

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Eosinophils; Glyceryl Ethers; Guinea Pigs; In Vitro Techniques; Indoles; Kinetics; Leukotriene B4; Male; Maleimides; Phenylpropionates; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptors, Leukotriene B4; Tetradecanoylphorbol Acetate; Time Factors

1995
Effects of protein kinase modulators on transferrin receptor expression in human leukaemic HL-60 cells.
    FEBS letters, 1995, May-29, Volume: 365, Issue:2-3

    Topics: Alkaloids; Bucladesine; Cell Division; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplasm; Enzyme Activation; Gene Expression; Humans; Indoles; Isoquinolines; Leukemia, Promyelocytic, Acute; Maleimides; Protein Kinase C; Protein Kinases; Receptors, Transferrin; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured

1995
Preferential inhibition of phorbol ester-induced hydrolysis of phosphatidylethanolamine by N-acetylsphingosine in NIH 3T3 fibroblasts.
    FEBS letters, 1995, May-29, Volume: 365, Issue:2-3

    Topics: 3T3 Cells; Animals; Carbon Radioisotopes; Fibroblasts; Hydrolysis; Indoles; Kinetics; Maleimides; Mice; Palmitic Acid; Palmitic Acids; Phosphatidylethanolamines; Phospholipase D; Protein Kinase C; Radioisotope Dilution Technique; Rats; Sphingosine; Tetradecanoylphorbol Acetate

1995
Thrombin and phorbol ester induce internalization of thrombin receptor of human mesangial cells through different pathways.
    Experimental cell research, 1995, Volume: 216, Issue:2

    Topics: Alkaloids; Cell Membrane Permeability; Glomerular Mesangium; Humans; Indoles; Maleimides; Peptide Fragments; Protein Kinase C; Receptors, Thrombin; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin

1995
The bisindolylmaleimide GF 109203X, a selective inhibitor of protein kinase C, does not inhibit the potentiating effect of phorbol ester on ethanol-induced phospholipase C-mediated hydrolysis of phosphatidylethanolamine.
    Biochimica et biophysica acta, 1995, Feb-16, Volume: 1265, Issue:1

    Topics: 3T3 Cells; Animals; Ethanol; Ethanolamines; Indoles; Maleimides; Mice; Phosphatidylethanolamines; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases

1995
Differential modulation of human fibroblast and keratinocyte growth by the protein kinase C inhibitor GF 109203X.
    Molecular pharmacology, 1994, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Blotting, Northern; Casein Kinase II; Cell Differentiation; Cell Division; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Epidermal Growth Factor; Female; Fibroblasts; Gene Expression; Genes, fos; Genes, jun; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Indoles; Keratinocytes; Maleimides; Middle Aged; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; RNA, Messenger; Tetradecanoylphorbol Acetate

1994
Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2.
    The Journal of biological chemistry, 1994, Jul-29, Volume: 269, Issue:30

    Topics: Animals; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Ethers, Cyclic; Gene Expression Regulation, Enzymologic; Indoles; Isoenzymes; Macrophages, Peritoneal; Maleimides; Mice; Okadaic Acid; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Zymosan

1994
Increase of c-jun mRNA upon hypo-osmotic cell swelling of rat hepatoma cells.
    FEBS letters, 1994, Mar-07, Volume: 340, Issue:3

    Topics: Animals; Cell Size; Enzyme Activation; Indoles; Liver Neoplasms, Experimental; Maleimides; Osmolar Concentration; Protein Kinase C; Proto-Oncogene Proteins c-jun; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1994
A protein kinase C-dependent activity modulates retinoic acid-induced transcription.
    Molecular endocrinology (Baltimore, Md.), 1993, Volume: 7, Issue:12

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Cell Line; Cell Nucleus; Chlorocebus aethiops; DNA; Enzyme Induction; Humans; Indoles; Isoenzymes; Isoquinolines; Maleimides; Molecular Sequence Data; Phosphorylation; Piperazines; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Protein Processing, Post-Translational; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tretinoin

1993
PMA inhibits the growth of human fibroblasts after the induction of immediate-early genes.
    Experimental cell research, 1994, Volume: 212, Issue:1

    Topics: Cell Cycle; Culture Media, Serum-Free; Fibroblasts; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Genes, jun; Humans; Indoles; Maleimides; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Thrombin

1994
Protein kinase C modulates the activity of a cloned gamma-aminobutyric acid transporter expressed in Xenopus oocytes via regulated subcellular redistribution of the transporter.
    The Journal of biological chemistry, 1994, May-20, Volume: 269, Issue:20

    Topics: Animals; Biological Transport; Brain; Carrier Proteins; Cloning, Molecular; Cyclosporine; Cytoplasm; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Golgi Apparatus; Indoles; Kinetics; Maleimides; Membrane Proteins; Membrane Transport Proteins; Nerve Tissue Proteins; Oocytes; Organic Anion Transporters; Protein Kinase C; Rats; Serotonin; Subcellular Fractions; Tetradecanoylphorbol Acetate; Xenopus

1994
N-protein kinase C isoenzymes may be involved in the regulation of various neutrophil functions.
    Biochemical and biophysical research communications, 1994, May-16, Volume: 200, Issue:3

    Topics: Carbazoles; Enzyme Activation; Humans; In Vitro Techniques; Indoles; Isoenzymes; Maleimides; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate

1994
Calpain-induced downregulation of activated protein kinase C-alpha affects lung epithelial cell morphology.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 1

    Topics: Animals; Calpain; Cell Line; Cell Line, Transformed; Cytosol; Epithelial Cells; Epithelium; Indoles; Isoenzymes; Kinetics; Lung; Maleimides; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors

1994
Anti-CD3 and phorbol ester induce distinct phosphorylated sites in the SH2 domain of p56lck.
    The Journal of biological chemistry, 1993, Dec-25, Volume: 268, Issue:36

    Topics: Amino Acid Sequence; Binding Sites; CD3 Complex; Cells, Cultured; Indoles; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Maleimides; Molecular Sequence Data; Peptide Mapping; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Serine; Tetradecanoylphorbol Acetate; Trypsin

1993
Anti-inflammatory properties of the protein kinase C inhibitor, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H- pyrrole-2,5-dione monohydrochloride (GF109203X) in the PMA-mouse ear edema model.
    Agents and actions, 1993, Volume: 39 Spec No

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Ear; Edema; Eicosanoids; Female; Indoles; Inflammation; Maleimides; Mice; Neutrophils; Peroxidase; Protein Kinase C; Radioimmunoassay; Tetradecanoylphorbol Acetate

1993
Muscarinic inhibition of ATP-sensitive K+ channels by protein kinase C in urinary bladder smooth muscle.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1

    Topics: Adenosine Triphosphate; Animals; Benzopyrans; Carbachol; Cromakalim; Diglycerides; Glyburide; Guanosine Diphosphate; Guinea Pigs; In Vitro Techniques; Indoles; Maleimides; Membrane Potentials; Muscarinic Antagonists; Muscle, Smooth; Potassium Channels; Protein Kinase C; Pyrroles; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Thionucleotides; Urinary Bladder

1993
The selective protein kinase C inhibitor GF 109203X inhibits phorbol ester-induced morphological and functional differentiation of SH-SY5Y human neuroblastoma cells.
    Biochemical and biophysical research communications, 1993, Dec-30, Volume: 197, Issue:3

    Topics: Blotting, Northern; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; GAP-43 Protein; Gene Expression; Genes, fos; Humans; Indoles; Kinetics; Maleimides; Membrane Glycoproteins; Molecular Weight; Nerve Tissue Proteins; Neurites; Neuroblastoma; Neuropeptide Y; Phosphoproteins; Phosphorylation; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Distinct mechanisms of phospholipase D activation and attenuation utilized by different mitogens in NIH-3T3 fibroblasts.
    European journal of biochemistry, 1993, Jul-15, Volume: 215, Issue:2

    Topics: 3T3 Cells; Alkaloids; Animals; Dinoprost; Dose-Response Relationship, Drug; Enzyme Activation; Hydrolysis; Indoles; Maleimides; Mice; Mitogens; Phosphatidic Acids; Phospholipase D; Phospholipids; Platelet-Derived Growth Factor; Staurosporine; Tetradecanoylphorbol Acetate

1993
Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity.
    The Journal of biological chemistry, 1993, Mar-25, Volume: 268, Issue:9

    Topics: 3T3 Cells; Animals; Biological Transport; Blotting, Northern; Blotting, Western; Brain; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cloning, Molecular; Enzyme Activation; Enzyme Stability; Indoles; Isoenzymes; Kinetics; Maleimides; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate

1993
Overexpression of epsilon-protein kinase C enhances nerve growth factor-induced phosphorylation of mitogen-activated protein kinases and neurite outgrowth.
    The Journal of biological chemistry, 1995, Dec-15, Volume: 270, Issue:50

    Topics: Amino Acid Sequence; Analysis of Variance; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Enzyme Inhibitors; Ethanol; Fluorescent Antibody Technique; Gene Expression; Indoles; Isoenzymes; Maleimides; Microscopy, Fluorescence; Molecular Sequence Data; Nerve Growth Factors; Neurites; PC12 Cells; Peptides; Phosphorylation; Protein Kinase C; Rats; Recombinant Proteins; Substrate Specificity; Tetradecanoylphorbol Acetate; Transfection

1995
Inhibition of protein kinase C suppresses megakaryocytic differentiation and stimulates erythroid differentiation in HEL cells.
    Blood, 1996, Jan-01, Volume: 87, Issue:1

    Topics: Aphidicolin; Biomarkers; Blood Proteins; Cell Cycle; Cell Differentiation; Enzyme Inhibitors; Erythroid Precursor Cells; Gene Expression Regulation, Leukemic; Globins; Glycophorins; Hematopoietic Stem Cells; Hemin; Humans; Indoles; Leukemia, Erythroblastic, Acute; Maleimides; Megakaryocytes; Neoplasm Proteins; Phorbol 12,13-Dibutyrate; Phosphoproteins; Phosphorylation; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Protein kinase C regulates tyrosine phosphorylation of pp125FAK in platelets adherent to fibrinogen.
    Blood, 1996, Jan-01, Volume: 87, Issue:1

    Topics: Adenosine Diphosphate; Apyrase; Blood Platelets; Calcium; Cell Adhesion Molecules; Cell Size; Egtazic Acid; Enzyme Inhibitors; Fibrinogen; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Maleimides; Phosphoproteins; Phosphorylation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Tyrosine

1996
1,25-dihydroxyvitamin D3 primes acute promyelocytic cells for TPA-induced monocytic differentiation through both PKC and tyrosine phosphorylation cascades.
    Experimental cell research, 1996, Jan-10, Volume: 222, Issue:1

    Topics: Alkaloids; Calcitriol; Cell Differentiation; Enzyme Inhibitors; Genistein; Humans; Indoles; Isoflavones; Leukemia, Promyelocytic, Acute; Maleimides; Monocytes; Phagocytosis; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates

1996
Phorbol ester-stimulated phosphorylation of PU.1: association with leukemic cell growth inhibition.
    Blood, 1996, May-15, Volume: 87, Issue:10

    Topics: Base Sequence; Bryostatins; Cell Differentiation; Cell Division; DNA, Neoplasm; Enhancer Elements, Genetic; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Humans; Indoles; Lactones; Lymphoma, Large B-Cell, Diffuse; Macrolides; Maleimides; Molecular Sequence Data; Neoplasm Proteins; Phosphorylation; Protein Binding; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogenes; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured

1996
Mechanism of apoptosis suppression by phorbol ester in IL-6-starved murine plasmacytomas: role of PKC modulation and cell cycle.
    Biochemistry, 1996, Jul-30, Volume: 35, Issue:30

    Topics: Alkaloids; Animals; Apoptosis; Benzophenanthridines; Cell Cycle; Cell Line; Cytosol; Enzyme Activation; Enzyme Inhibitors; Indoles; Interleukin-6; Isoenzymes; Lactams; Maleimides; Mice; Phenanthridines; Phorbol Esters; Plasmacytoma; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Modulation of keratinocyte growth factor (KGF) mRNA expression in human dermal fibroblasts grown in monolayer or within a collagen matrix.
    Experimental dermatology, 1996, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Breast; Cell Division; Cells, Cultured; Cholera Toxin; Culture Media, Conditioned; Enzyme Inhibitors; Epidermal Growth Factor; Female; Fibroblast Growth Factor 10; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Fibroblasts; Growth Substances; Humans; Indoles; Keratinocytes; Maleimides; Middle Aged; Protein Kinase C; RNA, Messenger; Signal Transduction; Skin; Surgery, Plastic; Tetradecanoylphorbol Acetate; Transcription, Genetic

1996
Inhibition of T lymphocyte activation by cAMP is associated with down-regulation of two parallel mitogen-activated protein kinase pathways, the extracellular signal-related kinase and c-Jun N-terminal kinase.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Aug-15, Volume: 157, Issue:4

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Humans; Indoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Leukemia-Lymphoma, Adult T-Cell; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphoma, T-Cell; Maleimides; Mice; Mitogen-Activated Protein Kinases; Mitogens; Molecular Sequence Data; Muromonab-CD3; Nerve Tissue Proteins; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Protein kinase C-epsilon is implicated in neurite outgrowth in differentiating human neuroblastoma cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:6

    Topics: Cell Differentiation; Down-Regulation; Enzyme Inhibitors; Growth Substances; Humans; Indoles; Isoenzymes; Maleimides; Neurites; Neuroblastoma; Neurons; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate; Transcription, Genetic

1996
The kinase inhibitor iso-H7 stimulates rat satellite cell differentiation through a non-protein kinase C pathway by increasing myogenin expression level.
    Cell biology and toxicology, 1996, Volume: 12, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blotting, Northern; Cell Differentiation; Creatine Kinase; Enzyme Inhibitors; Indoles; Isoquinolines; Maleimides; Muscle, Skeletal; Myogenin; Myosin Light Chains; Protein Kinase C; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Tetradecanoylphorbol Acetate

1996
Transcriptional control of the heme oxygenase gene in mouse M1 cells during their TPA-induced differentiation into macrophages.
    Journal of cellular biochemistry, 1996, Sep-01, Volume: 62, Issue:3

    Topics: Acetylcysteine; Animals; Binding Sites; Carcinogens; Cell Differentiation; Electrophoresis; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Heme Oxygenase (Decyclizing); Hydrogen Peroxide; Indoles; Leukemia, Myeloid; Macrophages; Maleimides; Mice; NF-kappa B; Nuclear Proteins; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured

1996
Direct proof that phorbol ester accelerates the use of choline phosphate for phosphatidylcholine synthesis in intact cells.
    Archives of biochemistry and biophysics, 1996, Nov-01, Volume: 335, Issue:1

    Topics: 3T3 Cells; Animals; Carbon Radioisotopes; Choline; Choline-Phosphate Cytidylyltransferase; Enzyme Inhibitors; Indoles; Kinetics; Maleimides; Mice; Nucleotidyltransferases; Phosphatidylcholines; Phosphorylcholine; Protein Kinase C; Radioisotope Dilution Technique; Tetradecanoylphorbol Acetate

1996
Protein kinase C activity and phosphoprotein pattern in stimulated alveolar macrophages.
    Toxicology letters, 1996, Volume: 88, Issue:1-3

    Topics: Animals; Cattle; Cytosol; Electrophoresis, Gel, Two-Dimensional; In Vitro Techniques; Indoles; Macrophage Activation; Macrophages, Alveolar; Maleimides; Phosphoproteins; Protein Kinase C; Rats; Spectrometry, Fluorescence; Staurosporine; Tetradecanoylphorbol Acetate

1996
Activation of G-proteins with AIF-4 induces LFA-1-mediated adhesion of T-cell hybridoma cells to ICAM-1 by signal pathways that differ from phorbol ester- and manganese-induced adhesion.
    Experimental cell research, 1997, Mar-15, Volume: 231, Issue:2

    Topics: Aluminum Compounds; Androstadienes; Animals; Cell Adhesion; Enzyme Activation; Enzyme Inhibitors; Estrenes; Fluorides; Genistein; GTP-Binding Proteins; Humans; Hybridomas; Indoles; Intercellular Adhesion Molecule-1; Isoflavones; Lymphocyte Function-Associated Antigen-1; Maleimides; Manganese; Mice; Neoplasm Invasiveness; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Protein-Tyrosine Kinases; Pyrrolidinones; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Wortmannin

1997
Inhibition of cytosolic phospholipase A2 by annexin V in differentiated permeabilized HL-60 cells. Evidence of crucial importance of domain I type II Ca2+-binding site in the mechanism of inhibition.
    The Journal of biological chemistry, 1997, Apr-18, Volume: 272, Issue:16

    Topics: Annexin A5; Arachidonic Acid; Bacterial Proteins; Binding Sites; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Membrane Permeability; Cytosol; Enzyme Inhibitors; Female; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Indoles; Kinetics; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Placenta; Pregnancy; Protein Kinase C; Recombinant Proteins; Streptolysins; Tetradecanoylphorbol Acetate

1997
Prostaglandin F2alpha stimulates tyrosine phosphorylation and mitogen-activated protein kinase in osteoblastic MC3T3-E1 cells via protein kinase C activation.
    Endocrinology, 1997, Volume: 138, Issue:5

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Dinoprost; Enzyme Activation; Enzyme Inhibitors; Immunosorbent Techniques; Indoles; Maleimides; Osteoblasts; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate

1997
Activation of ecto-5'-nucleotidase by protein kinase C and its role in ischaemic tolerance in the canine heart.
    British journal of pharmacology, 1997, Volume: 120, Issue:2

    Topics: 5'-Nucleotidase; Animals; Dogs; Enzyme Activation; Female; Hemodynamics; Indoles; Ischemic Preconditioning; Male; Maleimides; Myocardial Infarction; Myocardial Ischemia; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate

1997
CSF-1-induced and constitutive Il6 gene expression in mouse macrophages: evidence for PKC-dependent and -independent pathways.
    Experimental cell research, 1997, May-01, Volume: 232, Issue:2

    Topics: Animals; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation; Indoles; Interleukin-6; Macrophage Colony-Stimulating Factor; Macrophages, Peritoneal; Male; Maleimides; Mice; Mice, Inbred C57BL; Mice, SCID; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate

1997
Expression of CD44 isoforms in neuroblastoma cells is regulated by PI 3-kinase and protein kinase C.
    Oncogene, 1997, Jun-12, Volume: 14, Issue:23

    Topics: Carcinogens; Cell Adhesion; Enzyme Inhibitors; Humans; Hyaluronan Receptors; Hyaluronic Acid; Indoles; Insulin-Like Growth Factor I; Maleimides; Models, Molecular; Neuroblastoma; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Protein Kinase C; Signal Transduction; Surface Properties; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

1997
Phosphorylation of the respiratory burst oxidase subunit p67(phox) during human neutrophil activation. Regulation by protein kinase C-dependent and independent pathways.
    The Journal of biological chemistry, 1997, Jul-04, Volume: 272, Issue:27

    Topics: Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Lymphocyte Activation; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Peptide Mapping; Phosphoproteins; Phosphorylation; Protein Kinase C; Serine; Tetradecanoylphorbol Acetate

1997
N-6 and n-3 polyunsaturated fatty acids stimulate translocation of protein kinase Calpha, -betaI, -betaII and -epsilon and enhance agonist-induced NADPH oxidase in macrophages.
    The Biochemical journal, 1997, Jul-15, Volume: 325 ( Pt 2)

    Topics: Calcimycin; Docosahexaenoic Acids; Enzyme Inhibitors; Fatty Acids, Unsaturated; Histones; HL-60 Cells; Humans; Indoles; Ionophores; Isoenzymes; Luminescent Measurements; Macrophages; Maleimides; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate

1997
Activation of mitogen-activated protein kinase by the nociceptin receptor expressed in Chinese hamster ovary cells.
    FEBS letters, 1997, Jul-28, Volume: 412, Issue:2

    Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Chromones; Cricetinae; Cricetulus; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Nociceptin Receptor; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Opioid; Recombinant Proteins; Tetradecanoylphorbol Acetate; Wortmannin

1997
Down-regulation of gap junctional intercellular communication between osteoblastic MC3T3-E1 cells by basic fibroblast growth factor and a phorbol ester (12-O-tetradecanoylphorbol-13-acetate).
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1997, Volume: 12, Issue:8

    Topics: 3T3 Cells; Animals; Blotting, Northern; Blotting, Western; Carcinogens; Cell Communication; DNA; Dose-Response Relationship, Drug; Down-Regulation; Fibroblast Growth Factor 2; Gap Junctions; Humans; Indoles; Maleimides; Mice; Osteoblasts; Protein Kinase C; Recombinant Proteins; Tetradecanoylphorbol Acetate

1997
Cellular relocalisation of protein kinase C-theta caused by staurosporine and some of its analogues.
    Biochemical pharmacology, 1997, May-15, Volume: 53, Issue:10

    Topics: Alkaloids; Antineoplastic Agents; Blotting, Western; Cell Membrane; Cell Nucleus; Cytosol; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Humans; Indoles; Isoenzymes; Maleimides; Microscopy, Confocal; Models, Chemical; Protein Kinase C; Protein Kinase C-theta; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zinc Fingers

1997
Upregulation of CD9 expression during TPA treatment of K562 cells.
    Leukemia, 1997, Volume: 11, Issue:8

    Topics: Antigens, CD; Cell Differentiation; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Indoles; Integrin alpha1beta1; Integrins; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Maleimides; Megakaryocytes; Membrane Glycoproteins; Platelet Glycoprotein GPIIb-IIIa Complex; Promoter Regions, Genetic; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetraspanin 29; Time Factors; Tumor Cells, Cultured; Up-Regulation

1997
Role of protein kinases in the in vitro differentiation of human epidermal HaCaT cells.
    The British journal of dermatology, 1997, Volume: 137, Issue:1

    Topics: Adenine; Cell Differentiation; Cell Line; Enzyme Inhibitors; Epidermal Cells; Epidermis; Genistein; Humans; Indoles; Isoenzymes; Isoflavones; Keratinocytes; Maleimides; Okadaic Acid; Phosphoprotein Phosphatases; Protein Kinase C; Protein Kinases; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate

1997
Priming of mouse macrophages with the macrophage colony-stimulating factor (CSF-1) induces a variety of pathways that regulate expression of the interleukin 6 (Il6) and granulocyte-macrophage colony-stimulating factor (Csfgm) genes.
    Experimental cell research, 1997, Aug-25, Volume: 235, Issue:1

    Topics: Animals; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Indoles; Interleukin-6; Kinetics; Macrophage Colony-Stimulating Factor; Macrophages, Peritoneal; Male; Maleimides; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; Protein Kinase Inhibitors; Protein Kinases; Receptor, Macrophage Colony-Stimulating Factor; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Transcription, Genetic

1997
Roles for protein kinase C and mitogen-activated protein kinase in nicotine-induced secretion from bovine adrenal chromaffin cells.
    Journal of neurochemistry, 1997, Volume: 69, Issue:3

    Topics: Adrenal Medulla; Animals; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cells, Cultured; Chromaffin Cells; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Flavonoids; Indoles; Kinetics; Maleimides; Nicotine; Norepinephrine; Potassium Chloride; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate

1997
Effect of the protein kinase C inhibitor GF 109 203X on elastase release and respiratory burst of human neutrophils.
    General pharmacology, 1996, Volume: 27, Issue:8

    Topics: Calcimycin; Calcium; Enzyme Inhibitors; Exocytosis; Humans; In Vitro Techniques; Indoles; L-Lactate Dehydrogenase; Leukocyte Elastase; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate

1996
Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin.
    The Journal of biological chemistry, 1997, Oct-03, Volume: 272, Issue:40

    Topics: Amino Acid Sequence; beta Catenin; Consensus Sequence; Cytoskeletal Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Humans; I-kappa B Proteins; Indoles; Maleimides; Molecular Sequence Data; Mutagenesis, Site-Directed; Naphthalenes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Phosphoserine; Point Mutation; Protein Kinase C; Protein Processing, Post-Translational; Sequence Alignment; Serine; Substrate Specificity; Tetradecanoylphorbol Acetate; Trans-Activators; Ubiquitins

1997
Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver.
    Gastroenterology, 1997, Volume: 113, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Enzyme Activation; Enzyme Inhibitors; Flavonoids; GTP-Binding Proteins; Indoles; Isomerism; Isoproterenol; Kinetics; Liver; Male; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Signal Transduction; Taurochenodeoxycholic Acid; Taurocholic Acid; Tetradecanoylphorbol Acetate

1997
Inactivation of melatonin receptors by protein kinase C in human prostate epithelial cells.
    Endocrinology, 1997, Volume: 138, Issue:10

    Topics: Aged; Aged, 80 and over; Animals; Calcium Chloride; Carcinogens; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Epithelial Cells; Epithelium; Humans; Indoles; Iodine Radioisotopes; Male; Maleimides; Melatonin; Middle Aged; Prostate; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; Tetradecanoylphorbol Acetate; Thymidine; Tritium

1997
Role of protein kinase C-alpha in activation of ecto-5'-nucleotidase in the preconditioned canine myocardium.
    Biochemical and biophysical research communications, 1997, Oct-09, Volume: 239, Issue:1

    Topics: Adenosine Triphosphatases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Biological Transport; Blood Pressure; Cell Membrane; Dogs; Enzyme Activation; Enzyme Inhibitors; Heart Rate; Indoles; Ischemic Preconditioning, Myocardial; Isoenzymes; Maleimides; Methoxamine; Myocardium; Okadaic Acid; Prazosin; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate

1997
Both the catalytic and regulatory domains of protein kinase C chimeras modulate the proliferative properties of NIH 3T3 cells.
    The Journal of biological chemistry, 1997, Nov-07, Volume: 272, Issue:45

    Topics: 3T3 Cells; Animals; Binding Sites; Catalysis; Cell Division; Enzyme Inhibitors; Indoles; Isoenzymes; Maleimides; Mice; Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection

1997
Molecular mechanisms for the growth factor action of gastrin.
    The American journal of physiology, 1997, Volume: 273, Issue:4

    Topics: Animals; Benzodiazepinones; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Devazepide; DNA-Binding Proteins; Enzyme Inhibitors; ets-Domain Protein Elk-1; Flavonoids; Gastrins; Genes, fos; Hormone Antagonists; Humans; Indoles; Luciferases; Maleimides; Mitogen-Activated Protein Kinase 1; Pancreas; Pertussis Toxin; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Rats; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transcription Factors; Transcription, Genetic; Transfection; Virulence Factors, Bordetella

1997
Cholecystokinin-stimulated tyrosine phosphorylation of p125FAK and paxillin is mediated by phospholipase C-dependent and -independent mechanisms and requires the integrity of the actin cytoskeleton and participation of p21rho.
    The Biochemical journal, 1997, Oct-15, Volume: 327 ( Pt 2)

    Topics: Actins; Animals; Calcimycin; Calcium; Cell Adhesion Molecules; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Proteins; Indoles; Inositol Phosphates; Kinetics; Male; Maleimides; Models, Biological; Pancreas; Paxillin; Phospholipases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; rho GTP-Binding Proteins; Sincalide; Tetradecanoylphorbol Acetate; Tyrosine

1997
Neuromedin B receptor activation causes tyrosine phosphorylation of p125FAK by a phospholipase C independent mechanism which requires p21rho and integrity of the actin cytoskeleton.
    Biochemistry, 1997, Dec-23, Volume: 36, Issue:51

    Topics: Actin Cytoskeleton; Actins; ADP Ribose Transferases; Animals; Botulinum Toxins; Calcimycin; Calcium; Cell Adhesion Molecules; Colchicine; Cytochalasin D; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gastrin-Releasing Peptide; GTP-Binding Proteins; Indoles; Maleimides; Mice; Neurokinin B; Nitriles; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Bombesin; rho GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tumor Cells, Cultured; Type C Phospholipases; Tyrphostins

1997
Acetylcholine agonists stimulate mitogen-activated protein kinase in oligodendrocyte progenitors by muscarinic receptors.
    Journal of neuroscience research, 1997, Dec-01, Volume: 50, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Atropine; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Cholinergic Agents; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Oligodendroglia; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Stem Cells; Tetradecanoylphorbol Acetate

1997
P2U purinergic receptor inhibits apical IsK/KvLQT1 channel via protein kinase C in vestibular dark cells.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Base Sequence; Calcium Channels; Cloning, Molecular; DNA Primers; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Estrenes; Gerbillinae; Humans; In Vitro Techniques; Indoles; KCNQ Potassium Channels; KCNQ1 Potassium Channel; Maleimides; Membrane Potentials; Molecular Sequence Data; Polymerase Chain Reaction; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase C; Pyrrolidinones; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sequence Alignment; Tetradecanoylphorbol Acetate; Type C Phospholipases; Vestibule, Labyrinth

1997
Induction of 12-lipoxygenase expression by phorbol 12-myristate 13-acetate in human epidermoid carcinoma A431 cells.
    Biochimica et biophysica acta, 1998, Jan-05, Volume: 1389, Issue:1

    Topics: Arachidonate 12-Lipoxygenase; Base Sequence; Blotting, Western; Carcinoma, Squamous Cell; DNA-Binding Proteins; Enzyme Induction; Genes, Reporter; Humans; Indoles; Luciferases; Maleimides; Microsomes; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Proteins; Promoter Regions, Genetic; RNA, Messenger; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

1998
The microbial alkaloid toxin staurosporine blocks the phorbol ester-induced increase in beta-amyloid precursor protein in PC12 cells.
    Natural toxins, 1997, Volume: 5, Issue:5

    Topics: Alkaloids; Amyloid beta-Protein Precursor; Animals; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Indoles; Isomerism; Maleimides; PC12 Cells; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors

1997
Extracellular signal-regulated kinase (ERK) activity is required for TPA-mediated inhibition of drug-induced apoptosis.
    Biochemical and biophysical research communications, 1998, Apr-07, Volume: 245, Issue:1

    Topics: Anisomycin; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Protein Kinase C; Tetradecanoylphorbol Acetate

1998
Induction of apoptosis by hepatocyte growth factor/scatter factor and its augmentation by phorbol esters in Meth A cells.
    Biochemical and biophysical research communications, 1998, Apr-07, Volume: 245, Issue:1

    Topics: Animals; Apoptosis; Benzimidazoles; Cell Cycle; Cell Survival; DNA Fragmentation; DNA Replication; Flow Cytometry; Fluorescent Dyes; Hepatocyte Growth Factor; Indoles; Maleimides; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1998
Cross-talk between protein kinase C-alpha (PKC-alpha) and -delta (PKC-delta): PKC-alpha elevates the PKC-delta protein level, altering its mRNA transcription and degradation.
    Biochemistry, 1998, Apr-21, Volume: 37, Issue:16

    Topics: Animals; Enzyme Activation; Enzyme Stability; Indoles; Isoenzymes; Leukemia, Promyelocytic, Acute; Lymphoma, B-Cell; Maleimides; Mice; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation

1998
Osmotic swelling-induced activation of the extracellular-signal-regulated protein kinases Erk-1 and Erk-2 in intestine 407 cells involves the Ras/Raf-signalling pathway.
    The Biochemical journal, 1998, May-01, Volume: 331 ( Pt 3)

    Topics: ADP Ribose Transferases; Androstadienes; Botulinum Toxins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Size; Enzyme Activation; Epidermal Growth Factor; Flavonoids; Humans; Hypotonic Solutions; Indoles; Intestines; Iodine Radioisotopes; Maleimides; Osmotic Pressure; Phosphorylation; ras Proteins; Rubidium Radioisotopes; Signal Transduction; Tetradecanoylphorbol Acetate; Wortmannin

1998
Transforming G protein-coupled receptors block insulin and ras-induced adipocytic differentiation in 3T3-L1 cells: evidence for a PKC and MAP kinase independent pathway.
    Biochemical and biophysical research communications, 1998, Apr-17, Volume: 245, Issue:2

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adipocytes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Differentiation; GRB2 Adaptor Protein; GTP-Binding Proteins; Histocytochemistry; Indoles; Insulin; Insulin Receptor Substrate Proteins; Maleimides; Mice; Phosphoproteins; Phosphorylation; Protein Kinase C; Proteins; ras Proteins; Receptors, Muscarinic; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1998
Protein kinase C-alpha activity inversely modulates invasion and growth of intestinal cells.
    The Journal of biological chemistry, 1998, Jun-12, Volume: 273, Issue:24

    Topics: Animals; Cadherins; Carbazoles; Cell Adhesion; Cell Movement; Cell Size; Gene Expression Regulation, Neoplastic; Humans; Indoles; Maleimides; Mice; Mice, Nude; Mutagenesis, Site-Directed; Neoplasm Invasiveness; Neoplasms, Experimental; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator

1998
Desmosomes are regulated by protein kinase C in primary rat epithelial cells.
    Cell adhesion and communication, 1998, Volume: 5, Issue:1

    Topics: Animals; Cell Adhesion; Cells, Cultured; Cytoplasm; Desmosomes; Enzyme Inhibitors; Epithelial Cells; Indoles; Keratinocytes; Macromolecular Substances; Maleimides; Microscopy, Electron; Microscopy, Fluorescence; Morphogenesis; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tongue

1998
Simultaneous cross-linking of CD6 and CD28 induces cell proliferation in resting T cells.
    Immunology, 1998, Volume: 93, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Antibodies, Monoclonal; Antigens, CD; Carcinogens; CD28 Antigens; CD3 Complex; Cell Division; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Indoles; Interleukin-2; Lymphocyte Activation; Maleimides; Protein Kinase C; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate

1998
Induction of cell death by stimulation of protein kinase C in human epithelial cells expressing a mutant ras oncogene: a potential therapeutic target.
    British journal of cancer, 1998, Volume: 78, Issue:5

    Topics: Apoptosis; Blotting, Western; Cell Death; Cell Line; Down-Regulation; Electrophoresis, Agar Gel; Epithelial Cells; Genes, ras; Humans; Indoles; Maleimides; Microscopy, Electron; Mutation; Protein Kinase C; ras Proteins; Tetradecanoylphorbol Acetate; Thyroid Gland

1998
The role of protein kinase C signaling in activated DRA transcription.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Nov-01, Volume: 161, Issue:9

    Topics: B-Lymphocytes; Burkitt Lymphoma; Cell Membrane; Cytosol; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; HLA-DR alpha-Chains; HLA-DR Antigens; Humans; Indoles; Isoenzymes; Maleimides; Microscopy, Fluorescence; Promoter Regions, Genetic; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transfection

1998
Interleukin-1alpha and tumor necrosis factor alpha synergistically stimulate prostaglandin E2-dependent production of interleukin-11 in rheumatoid synovial fibroblasts.
    Arthritis and rheumatism, 1998, Volume: 41, Issue:11

    Topics: Arthritis, Rheumatoid; Carcinogens; Cells, Cultured; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Indoles; Interleukin-1; Interleukin-11; Isoquinolines; Maleimides; Protein Kinase C; Signal Transduction; Sulfonamides; Synovial Membrane; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1998
The role of protein kinase C alpha and epsilon isozymes in DNA synthesis induced by muscarinic receptors in a glial cell line.
    European journal of pharmacology, 1998, Oct-23, Volume: 359, Issue:2-3

    Topics: Astrocytoma; Atropine; Carbachol; Carcinogens; DNA; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Maleimides; Muscarinic Agonists; Muscarinic Antagonists; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Radioligand Assay; Receptors, Muscarinic; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured

1998
Role of p38 MAP kinase in myocardial stress.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:8

    Topics: Adenosine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Imidazoles; Indoles; Ischemic Preconditioning, Myocardial; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Myocardial Ischemia; Myocardium; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Rats; Tetradecanoylphorbol Acetate

1998
Pervanadate activates NADPH oxidase via protein kinase C-independent phosphorylation of p47-phox.
    Archives of biochemistry and biophysics, 1999, Jan-01, Volume: 361, Issue:1

    Topics: Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Enzyme Activation; Guinea Pigs; Indoles; Maleimides; Mice; Molecular Sequence Data; NADPH Dehydrogenase; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Protein Tyrosine Phosphatases; Superoxides; Tetradecanoylphorbol Acetate; Vanadates

1999
Transcriptional activation of gonadotropin-releasing hormone (GnRH) receptor gene by GnRH: involvement of multiple signal transduction pathways.
    Endocrinology, 1999, Volume: 140, Issue:1

    Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genes, Reporter; Gonadotropin-Releasing Hormone; Indoles; Maleimides; Mice; Pituitary Gland; Promoter Regions, Genetic; Protein Kinase C; Proto-Oncogene Proteins c-raf; Rats; Receptors, LHRH; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation; Transfection

1999
Intracellular signaling mechanisms of interleukin-1beta in synovial fibroblasts.
    The American journal of physiology, 1999, Volume: 276, Issue:1

    Topics: Animals; Calcimycin; Calcium Channel Blockers; Cell Line; Enzyme Inhibitors; Fibroblasts; Indoles; Interleukin-1; Intracellular Membranes; Ionophores; Maleimides; Nifedipine; Rabbits; Signal Transduction; Synovial Membrane; Tetradecanoylphorbol Acetate; Verapamil

1999
Specific signaling pathways in the regulation of TNF-alpha mRNA synthesis and TNF-alpha secretion in RBL-2H3 mast cells stimulated through the high affinity IgE receptor.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:12

    Topics: Androstadienes; Animals; beta-N-Acetylhexosaminidases; Egtazic Acid; Enzyme Inhibitors; Gene Expression; Indoles; Leukemia, Basophilic, Acute; Maleimides; Mast Cells; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Rats; Receptors, IgE; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleases; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Wortmannin

1998
Bradykinin stimulates interleukin-8 production by human lung fibroblasts.
    Immunology, 1998, Volume: 95, Issue:4

    Topics: Blotting, Northern; Bradykinin; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Gene Expression; Humans; Indoles; Interleukin-1; Interleukin-8; Lung; Maleimides; Protein Kinase C; Receptors, Interleukin-1; Recombinant Proteins; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors

1998
Resistance to TNF-alpha cytotoxicity can be achieved through different signaling pathways in rat mesangial cells.
    The American journal of physiology, 1999, Volume: 276, Issue:2

    Topics: Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle Proteins; Cells, Cultured; Cycloheximide; Drug Resistance; Dual Specificity Phosphatase 1; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Immediate-Early Proteins; Indoles; JNK Mitogen-Activated Protein Kinases; Male; Maleimides; Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Protein Kinase C; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

1999
Sp1 is involved in a protein kinase C-independent activation of human T cell leukemia virus type I long terminal repeat by 12-O-tetradecanoylphorbol-13-acetate.
    Virology, 1999, Feb-15, Volume: 254, Issue:2

    Topics: Anti-Inflammatory Agents; Base Sequence; Enzyme Inhibitors; Gene Products, tax; HIV Long Terminal Repeat; Human T-lymphotropic virus 1; Humans; Indoles; Jurkat Cells; Maleimides; Molecular Sequence Data; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Restriction Mapping; Sp1 Transcription Factor; Terminal Repeat Sequences; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation

1999
Involvement of p21 in the PKC-induced regulation of the G2/M cell cycle transition.
    FEBS letters, 1999, Feb-05, Volume: 444, Issue:1

    Topics: Aphidicolin; CDC2 Protein Kinase; Cyclin B; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; G2 Phase; Humans; Indoles; Maleimides; Mitosis; Phosphorylation; Precipitin Tests; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

1999
Phosphatidylinositol 3-kinase and protein kinase C are required for the inhibition of caspase activity by epidermal growth factor.
    FEBS letters, 1999, Feb-05, Volume: 444, Issue:1

    Topics: Alkaloids; Androstadienes; Apoptosis; Benzophenanthridines; Blotting, Western; Caspase 3; Caspase Inhibitors; Caspases; Chromatin; Chromones; DNA Fragmentation; Enzyme Precursors; Epidermal Growth Factor; Flow Cytometry; Humans; Indoles; Maleimides; Molecular Weight; Morpholines; Phenanthridines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Wortmannin

1999
Protein kinase C mediates experimental colitis in the rat.
    The American journal of physiology, 1999, Volume: 276, Issue:3

    Topics: Animals; Colitis; Colon; Enzyme Inhibitors; Ethanol; Indoles; Intestinal Mucosa; Isoenzymes; Male; Maleimides; Neutropenia; Peroxidase; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate; Trinitrobenzenesulfonic Acid

1999
The essential role of phorbol ester-sensitive protein kinase C isoforms in activation-induced cell death of Th1 cells.
    European journal of immunology, 1999, Volume: 29, Issue:3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Indoles; Isoenzymes; Maleimides; Membrane Glycoproteins; Mice; Mice, Transgenic; Mitogens; Protein Kinase C; Tetradecanoylphorbol Acetate; Th1 Cells; Th2 Cells

1999
1,25-dihydroxyvitamin D3 and TPA activate phospholipase D in Caco-2 cells: role of PKC-alpha.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Caco-2 Cells; Calcitriol; Calcium; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Ionomycin; Isoenzymes; Kinetics; Maleimides; Phospholipase D; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Tetradecanoylphorbol Acetate

1999
Regulation of actin cytoskeleton in lymphocytes: PKC-delta disrupts IL-3-induced membrane ruffles downstream of Rac1.
    Journal of cellular physiology, 1999, Volume: 179, Issue:2

    Topics: Actins; Animals; B-Lymphocytes; Cell Line; Cell Membrane; Cell Size; Cytochalasin D; Cytoskeleton; GTP-Binding Proteins; Indoles; Interleukin-3; Isoenzymes; Maleimides; Mice; Phenotype; Protein Kinase C; Protein Kinase C-delta; rac GTP-Binding Proteins; Tetradecanoylphorbol Acetate; Tubulin

1999
The role of protein kinases A and C pathways in the regulation of mitogen-activated protein kinase activation in response to gonadotropin-releasing hormone receptor activation.
    Endocrinology, 1999, Volume: 140, Issue:5

    Topics: Animals; Bucladesine; Buserelin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Indoles; Kinetics; Maleimides; Protein Kinase C; Rats; Receptors, LHRH; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection

1999
VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells.
    Oncogene, 1999, Apr-01, Volume: 18, Issue:13

    Topics: 3T3 Cells; Adenoviridae; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Chromones; DNA Replication; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genes, ras; Genetic Vectors; Indoles; Lymphokines; Maleimides; MAP Kinase Kinase Kinase 1; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Isoforms; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

1999
Hyperglycemia in vitro attenuates insulin-stimulated chemokinesis in normal human neutrophils. Role of protein kinase C activation.
    Journal of leukocyte biology, 1999, Volume: 65, Issue:5

    Topics: Adult; Cell Movement; Cell Size; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Hyperglycemia; Indoles; Insulin; Maleimides; Neutrophils; Protein Kinase C; Tetradecanoylphorbol Acetate

1999
Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.
    Cancer research, 1999, May-15, Volume: 59, Issue:10

    Topics: Alleles; Amino Acid Substitution; Calcium-Calmodulin-Dependent Protein Kinases; Chromones; Colonic Neoplasms; Culture Media, Serum-Free; Depression, Chemical; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Immediate-Early; Genes, ras; Humans; Indoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Maleimides; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Mutation, Missense; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils.
    The Journal of biological chemistry, 1999, Jun-18, Volume: 274, Issue:25

    Topics: Androstadienes; Chromones; Enzyme Activation; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Indoles; Leukotriene B4; Maleimides; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Binding; Protein Serine-Threonine Kinases; rac GTP-Binding Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella; Wortmannin

1999
Involvement of group VI Ca2+-independent phospholipase A2 in protein kinase C-dependent arachidonic acid liberation in zymosan-stimulated macrophage-like P388D1 cells.
    The Journal of biological chemistry, 1999, Jul-09, Volume: 274, Issue:28

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Diglycerides; Egtazic Acid; Group VI Phospholipases A2; Indoles; Leukemia P388; Maleimides; Mice; Naphthalenes; Oligonucleotides, Antisense; Organophosphonates; Phospholipases A; Phospholipases A2; Protein Kinase C; Pyrones; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Zymosan

1999
Role of diacylglycerol (DAG) in hormonal induction of S phase in hepatocytes: the DAG-dependent protein kinase C pathway is not activated by epidermal growth factor (EGF), but is involved in mediating the enhancement of responsiveness to EGF by vasopressi
    Journal of cellular physiology, 1999, Volume: 180, Issue:2

    Topics: Angiotensin II; Animals; Bacterial Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cells, Cultured; Diglycerides; DNA; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; G1 Phase; GTP-Binding Proteins; Indoles; Liver; Male; Maleimides; Neuropeptides; Norepinephrine; Phospholipase D; Protein Kinase C; Rats; Rats, Wistar; S Phase; Tetradecanoylphorbol Acetate; Vasopressins

1999
PAR1 activation initiates integrin engagement and outside-in signalling in megakaryoblastic CHRF-288 cells.
    Biochimica et biophysica acta, 1999, Jul-08, Volume: 1450, Issue:3

    Topics: Blood Platelets; Calcium; Cell Adhesion; Cell Cycle Proteins; Cell Line; Fibrinogen; Humans; Indoles; Maleimides; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin

1999
Sphingosine and phorbol ester modulate protein kinase C activity and modify ATP-evoked calcium mobilization in glioma C6 cells.
    Biochemical and biophysical research communications, 1999, Jul-14, Volume: 260, Issue:3

    Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Endoplasmic Reticulum; Enzyme Activation; Glioma; Indoles; Maleimides; Protein Kinase C; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Tumor Cells, Cultured; Type C Phospholipases

1999
Evidence on the participation of protein kinase C alpha in the proliferation of cultured myoblasts.
    Journal of cellular biochemistry, 1999, Aug-01, Volume: 74, Issue:2

    Topics: Animals; Cell Differentiation; Cell Division; Chick Embryo; DNA Replication; Indoles; Isoenzymes; Maleimides; Muscle, Skeletal; Naphthalenes; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate

1999
Opposite effects of Ras or PKC activation on the expression of the SPRR2A keratinocyte terminal differentiation marker.
    Experimental cell research, 1999, Aug-01, Volume: 250, Issue:2

    Topics: Calcium; Cell Differentiation; Cells, Cultured; Cornified Envelope Proline-Rich Proteins; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation; Genes, fos; Humans; Indoles; Keratinocytes; Maleimides; Membrane Proteins; Mutation; Oncogene Protein p21(ras); Promoter Regions, Genetic; Protein Kinase C; Protein Precursors; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic

1999
Involvement of desmoplakin phosphorylation in the regulation of desmosomes by protein kinase C, in HeLa cells.
    Cell adhesion and communication, 1999, Volume: 7, Issue:2

    Topics: Animals; Cytoskeletal Proteins; Desmogleins; Desmoplakins; Desmosomes; Enzyme Inhibitors; gamma Catenin; HeLa Cells; Humans; Indoles; Maleimides; Mice; Phosphorylation; Protein Kinase C; Solubility; Tetradecanoylphorbol Acetate

1999
Thioredoxin reductase is the major selenoprotein expressed in human umbilical-vein endothelial cells and is regulated by protein kinase C.
    The Biochemical journal, 1999, Aug-15, Volume: 342 ( Pt 1)

    Topics: Blotting, Western; Calcimycin; Calcium; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Indoles; Maleimides; Molecular Weight; Organ Specificity; Protein Kinase C; Proteins; Selenoproteins; Sodium Selenite; Tetradecanoylphorbol Acetate; Thioredoxin-Disulfide Reductase; Thyroid Gland; Time Factors; Tumor Cells, Cultured; Umbilical Veins

1999
Role of protein kinase C in facilitation of luteinizing hormone (LH)-releasing hormone-induced LH surges by neuropeptide Y.
    Endocrinology, 1999, Volume: 140, Issue:8

    Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; In Vitro Techniques; Indoles; Kinetics; Luteinizing Hormone; Maleimides; Neuropeptide Y; Pituitary Gland, Anterior; Proestrus; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, LHRH; Tetradecanoylphorbol Acetate; Time Factors

1999
A role of protein kinase C in the regulation of cytosolic phospholipase A(2) in bradykinin-induced PGI(2) synthesis by human vascular endothelial cells.
    Microvascular research, 1999, Volume: 58, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Base Sequence; Bradykinin; Calcium; Cells, Cultured; Cytosol; DNA Primers; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Humans; Indoles; Inositol 1,4,5-Trisphosphate; Kinetics; Maleimides; Mutagenesis, Site-Directed; Phospholipases A; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate

1999
Distinct protein kinase C isozymes signal mitogenesis and apoptosis in human colon cancer cells.
    Gastroenterology, 1999, Volume: 117, Issue:4

    Topics: Acetamides; Antineoplastic Agents; Apoptosis; Biological Transport; Colonic Neoplasms; Colorectal Neoplasms; Down-Regulation; Enzyme Inhibitors; Ethers, Cyclic; Humans; Indoles; Isoenzymes; Maleimides; Mitosis; Osmolar Concentration; Protein Kinase C; Pyrans; Signal Transduction; Spiro Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1999
Bradykinin induces interleukin-6 expression in astrocytes through activation of nuclear factor-kappaB.
    Journal of neurochemistry, 1999, Volume: 73, Issue:4

    Topics: Animals; Animals, Newborn; Astrocytes; Benzylamines; Bradykinin; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Interleukin-6; Kinetics; Luciferases; Maleimides; Mice; NF-kappa B; Promoter Regions, Genetic; Protein Kinase C; Recombinant Fusion Proteins; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin; Transcription, Genetic; Transfection

1999
Cholecystokinin activates PYK2/CAKbeta by a phospholipase C-dependent mechanism and its association with the mitogen-activated protein kinase signaling pathway in pancreatic acinar cells.
    The Journal of biological chemistry, 1999, Oct-29, Volume: 274, Issue:44

    Topics: Adaptor Proteins, Signal Transducing; Animals; Biological Transport; Calcimycin; Calcium; Cell Adhesion Molecules; Cholecystokinin; Colchicine; Cytochalasin D; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; GRB2 Adaptor Protein; In Vitro Techniques; Indoles; Male; Maleimides; MAP Kinase Signaling System; Models, Biological; Pancreas; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptors, Cholecystokinin; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases

1999
Gq/11-coupled receptors and protein synthesis in rat cardiomyocytes: role of Gi-proteins and protein kinase C-isozymes.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Fatty Acids, Unsaturated; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Proteins; Heart Ventricles; Hydrazines; Indoles; Inositol Phosphates; Isoenzymes; Maleimides; Norepinephrine; Pertussis Toxin; Phenylalanine; Protein Biosynthesis; Protein Kinase C; Proteins; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Tritium; Virulence Factors, Bordetella

1999
Stimulation of A(2A) adenosine receptor phosphorylation by protein kinase C activation: evidence for regulation by multiple protein kinase C isoforms.
    Biochemistry, 1999, Nov-09, Volume: 38, Issue:45

    Topics: Acetophenones; Animals; Benzopyrans; Carbazoles; CHO Cells; Consensus Sequence; Cricetinae; Cyclic AMP; Dogs; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Glioma; Indoles; Isoenzymes; Maleimides; Mutagenesis, Site-Directed; Phosphorylation; Protein Kinase C; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Signal Transduction; Tetradecanoylphorbol Acetate; Triazines; Triazoles; Tumor Cells, Cultured

1999
'Outside-in' signalling mechanisms underlying CD11b/CD18-mediated NADPH oxidase activation in human adherent blood eosinophils.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: Androstadienes; Carbazoles; CD18 Antigens; Cell Adhesion; Cell Count; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Humans; Imidazoles; Indoles; Isoenzymes; Macrophage-1 Antigen; Maleimides; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrazoles; Pyridines; Pyrimidines; Signal Transduction; src-Family Kinases; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin

1999
The involvement of protein kinase C in nitric oxide-induced damage to rat isolated colonic mucosal cells.
    British journal of pharmacology, 1999, Volume: 128, Issue:6

    Topics: Animals; Azoles; Cell Survival; Colon; Cyclic N-Oxides; Dose-Response Relationship, Drug; Enzyme Activation; Imidazoles; Indoles; Intestinal Mucosa; Isoenzymes; Isoindoles; Male; Maleimides; Nitric Oxide; Nitric Oxide Donors; Organoselenium Compounds; Penicillamine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate

1999
Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: blockade of p38 mitogen-activated protein kinase.
    Neuroscience, 1999, Volume: 94, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Brain-Derived Neurotrophic Factor; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Culture Media, Serum-Free; Cycloheximide; Enzyme Inhibitors; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Kinetics; Maleimides; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Neurons; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phorbol Esters; Protein Kinase C; Pyridines; Staurosporine; Tetradecanoylphorbol Acetate

1999
Mechanisms involved in desensitization of particulate guanylyl cyclase in human airway smooth muscle: the role of protein kinase C.
    Biochemical and biophysical research communications, 1999, Dec-09, Volume: 266, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Guanylate Cyclase; Humans; Indoles; Maleimides; Muscle, Smooth; Phorbols; Phosphodiesterase Inhibitors; Protein Kinase C; Respiratory System; Solubility; Tetradecanoylphorbol Acetate; Time Factors

1999
Activation of protein kinase C is required for the stable attachment of adherent platelets to collagen but is not needed for the initial rapid adhesion under flow conditions.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:12

    Topics: Animals; Antibodies; Blood Flow Velocity; Blood Platelets; Blood Proteins; Carbazoles; Carcinogens; Cell Adhesion Molecules; Collagen; Enzyme Inhibitors; Enzyme Precursors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Indoles; Integrins; Intracellular Signaling Peptides and Proteins; Maleimides; Phosphoproteins; Phosphorylation; Platelet Adhesiveness; Protein Conformation; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Receptors, Collagen; Skin; Stimulation, Chemical; Syk Kinase; Tetradecanoylphorbol Acetate; Tyrosine

1999
Rapid signalling by androgen receptor in prostate cancer cells.
    Oncogene, 1999, Nov-04, Volume: 18, Issue:46

    Topics: Adenocarcinoma; Androgen Antagonists; Cell Nucleus; Cytoplasm; Dihydrotestosterone; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Indoles; Ligands; Male; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Receptors, Androgen; Recombinant Fusion Proteins; Testosterone; Tetradecanoylphorbol Acetate; Transcription Factors; Transfection; Tumor Cells, Cultured

1999
PKC-epsilon regulates basolateral endocytosis in human T84 intestinal epithelia: role of F-actin and MARCKS.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: Acetophenones; Acetylcholine; Actin Cytoskeleton; Actins; Amino Acid Sequence; Benzopyrans; Biological Transport; Carbachol; Carbazoles; Carcinogens; Cell Membrane; Cell Polarity; Cells, Cultured; Cholinergic Agonists; Cross-Linking Reagents; Cytochalasin D; Diglycerides; Endocytosis; Enzyme Inhibitors; Epithelial Cells; Humans; Indoles; Intestines; Intracellular Signaling Peptides and Proteins; Isoenzymes; Maleimides; Membrane Proteins; Molecular Sequence Data; Myristoylated Alanine-Rich C Kinase Substrate; Nucleic Acid Synthesis Inhibitors; Pinocytosis; Protein Kinase C; Protein Kinase C-epsilon; Proteins; Tetradecanoylphorbol Acetate

1999
Effect of contraction on mitogen-activated protein kinase signal transduction in skeletal muscle. Involvement Of the mitogen- and stress-activated protein kinase 1.
    The Journal of biological chemistry, 2000, Jan-14, Volume: 275, Issue:2

    Topics: 3-O-Methylglucose; Amino Acid Sequence; Animals; Biological Transport; Electric Stimulation; Enzyme Inhibitors; Flavonoids; Glycogen; Imidazoles; In Vitro Techniques; Indoles; Insulin; Male; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Phosphopeptides; Phosphorylation; Pyridines; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate

2000
Exposure to 60-Hz magnetic fields and proliferation of human astrocytoma cells in vitro.
    Toxicology and applied pharmacology, 2000, Feb-01, Volume: 162, Issue:3

    Topics: Animals; Astrocytoma; Brain Neoplasms; Carbachol; Carcinogens; Cell Division; Cerebral Cortex; Cholinergic Agents; Cold Temperature; DNA Replication; DNA, Neoplasm; Drug Synergism; Electromagnetic Fields; Enzyme Inhibitors; Humans; Indoles; Maleimides; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2000
Interleukin-1beta regulates CFTR expression in human intestinal T84 cells.
    Biochimica et biophysica acta, 2000, Feb-21, Volume: 1500, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenocarcinoma; Benzoquinones; Cell Line; Colon; Colonic Neoplasms; Cycloheximide; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Genistein; Humans; Indoles; Interleukin-1; Lactams, Macrocyclic; Maleimides; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Quinones; Rifabutin; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

2000
Inhibition of bradykinin-induced phosphoinositide hydrolysis and Ca2+ mobilisation by phorbol ester in rat cultured vascular smooth muscle cells.
    Cellular signalling, 1999, Volume: 11, Issue:12

    Topics: Animals; Biological Transport; Bradykinin; Calcium Signaling; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Indoles; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Maleimides; Muscle, Smooth, Vascular; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Staurosporine; Tetradecanoylphorbol Acetate

1999
CCK stimulates mob-1 expression and NF-kappaB activation via protein kinase C and intracellular Ca(2+).
    American journal of physiology. Cell physiology, 2000, Volume: 278, Issue:2

    Topics: Animals; Biological Transport; Calcium; Carcinogens; Cell Nucleus; Chelating Agents; Chemokine CXCL10; Chemokines, CXC; Cholecystokinin; Cytokines; DNA-Binding Proteins; Egtazic Acid; Enzyme Inhibitors; Gene Expression; In Vitro Techniques; Indoles; Ionomycin; Ionophores; Male; Maleimides; NF-kappa B; Pancreas; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; RNA, Messenger; Tetradecanoylphorbol Acetate

2000
A protein kinase C-independent pathway leading to c-Jun-dependent expression of 100-kDa Ras GTPase-activating protein in JEG-3 human choriocarcinoma cells.
    European journal of biochemistry, 2000, Volume: 267, Issue:6

    Topics: Cell Differentiation; Choriocarcinoma; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Molecular Weight; Neoplasm Proteins; Okadaic Acid; Oligonucleotides, Antisense; Protein Isoforms; Protein Kinase C; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; ras GTPase-Activating Proteins; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uterine Neoplasms

2000
Induction of cell cornification and enhanced squamous-cell marker SPRR1 gene expression by phorbol ester are regulated by different signaling pathways in human conducting airway epithelial cells.
    American journal of respiratory cell and molecular biology, 2000, Volume: 22, Issue:5

    Topics: Biomarkers; Cell Size; Cornified Envelope Proline-Rich Proteins; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Gene Expression Regulation; Humans; Indoles; Lactams; Maleimides; Membrane Proteins; Microscopy, Phase-Contrast; Mitogen-Activated Protein Kinases; Protein Kinase C; Proteins; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Transcriptional Activation

2000
The m3 muscarinic acetylcholine receptor is coupled to mitogen-activated protein kinase via protein kinase C and epidermal growth factor receptor kinase.
    The Biochemical journal, 2000, Jun-01, Volume: 348 Pt 2

    Topics: Carbachol; Cell Line; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Protein Kinase C; Receptor, Muscarinic M3; Receptors, Muscarinic; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection

2000
Differential effects of protein kinase C on the levels of epithelial Na+ channel subunit proteins.
    The Journal of biological chemistry, 2000, Aug-18, Volume: 275, Issue:33

    Topics: Aldosterone; Animals; Biological Transport; Blotting, Western; Cell Line; Dose-Response Relationship, Drug; Electrophysiology; Enzyme Activation; Enzyme Inhibitors; Epithelial Sodium Channels; Indoles; Kinetics; Maleimides; Naphthalenes; Protein Kinase C; Protein Structure, Tertiary; RNA, Messenger; Sodium; Sodium Channels; Tetradecanoylphorbol Acetate; Time Factors; Xenopus

2000
Dexamethasone inhibits the induction of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase by phorbol ester in human promonocytic U937 cells.
    Biochimica et biophysica acta, 2000, Jun-02, Volume: 1497, Issue:1

    Topics: Anti-Inflammatory Agents; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Hydroxyprostaglandin Dehydrogenases; Indoles; Maleimides; Mifepristone; Phorbol Esters; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; U937 Cells

2000
Inhibition and stimulation of growth of Entamoeba histolytica in culture: association with PKC activity and protein phosphorylation.
    Experimental parasitology, 2000, Volume: 95, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Culture Media; Down-Regulation; Entamoeba histolytica; Enzyme Inhibitors; Indoles; Maleimides; Marine Toxins; Okadaic Acid; Oxazoles; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Threonine

2000
4-Hydroxynonenal-induced MEL cell differentiation involves PKC activity translocation.
    Biochemical and biophysical research communications, 2000, May-27, Volume: 272, Issue:1

    Topics: Aldehydes; Animals; Biological Transport, Active; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Enzyme Inhibitors; Hemoglobins; Indoles; Leukemia, Erythroblastic, Acute; Maleimides; Mice; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2000
Protein kinase C activity modulates dendritic differentiation of rat Purkinje cells in cerebellar slice cultures.
    The European journal of neuroscience, 2000, Volume: 12, Issue:6

    Topics: Animals; Carcinogens; Cell Differentiation; Cell Size; Dendrites; Enzyme Inhibitors; Indoles; Isoenzymes; Maleimides; Organ Culture Techniques; Protein Kinase C; Purkinje Cells; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tetrodotoxin

2000
Modulation of neutrophil migration and superoxide anion release by metoprolol.
    Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:6

    Topics: Adrenergic beta-Antagonists; Cells, Cultured; Chemotaxis, Leukocyte; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Maleimides; Metoprolol; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Respiratory Burst; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Time Factors

2000
Different regulation of phospholipase D activity in glioma C6 cells by sphingosine, propranolol, imipramine and phorbol ester.
    Cellular signalling, 2000, Volume: 12, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Compartmentation; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Glioma; Imipramine; Indoles; Isoenzymes; Maleimides; Neoplasm Proteins; Phospholipase D; Propranolol; Protein Kinase C; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2000
The effect of rapamycin on single ENaC channel activity and phosphorylation in A6 cells.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:1

    Topics: Drug Interactions; Enzyme Inhibitors; Epithelial Sodium Channels; Immunophilins; Immunosuppressive Agents; Indoles; Maleimides; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Sirolimus; Sodium Channels; Tacrolimus; Tacrolimus Binding Proteins; Tetradecanoylphorbol Acetate

2000
Changes in activity and regulation of the cardiac Ca2+ channel (L-type) by protein kinase C in chronic alcohol-exposed rats.
    Alcoholism, clinical and experimental research, 2000, Volume: 24, Issue:8

    Topics: Alcoholism; Animals; Calcium Channels, L-Type; Electric Stimulation; Enzyme Inhibitors; Ethanol; Indoles; Isoenzymes; Maleimides; Manganese; Myocardium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

2000
Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD.
    The Journal of biological chemistry, 2000, Nov-24, Volume: 275, Issue:47

    Topics: bcl-Associated Death Protein; Carrier Proteins; Cell Line; Cell Survival; Humans; Indoles; Isoenzymes; Maleimides; Phosphorylation; Protein Kinase C; Protein Kinase C-theta; Protein Kinases; Ribosomal Protein S6 Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate

2000
Phorbor myristate acetate induces NADPH oxidase activity of cytochalasin B-primed neutrophils through the protein kinase C-independent pathway.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:9

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Androstadienes; Cytochalasin B; Ethanol; Granulocyte Colony-Stimulating Factor; Humans; Indoles; Maleimides; NADPH Oxidases; Neutrophils; Phosphatidylinositol 3-Kinases; Phospholipase D; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin

2000
Role of protein kinase C in alpha(1)-adrenergic regulation of a(Na)(i) in guinea pig ventricular myocytes.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Enzyme Inhibitors; Extracellular Space; Guinea Pigs; Heart Ventricles; Indoles; Intracellular Membranes; Maleimides; Myocardium; Phenylephrine; Potassium; Protein Kinase C; Receptors, Adrenergic, alpha; Sodium; Staurosporine; Strophanthidin; Tetradecanoylphorbol Acetate; Tetrodotoxin

2000
Permissive role of protein kinase C alpha but not protein kinase C delta in sphingosine 1-phosphate-induced Rho A activation in C2C12 myoblasts.
    FEBS letters, 2000, Sep-29, Volume: 482, Issue:1-2

    Topics: Acetophenones; Animals; Benzopyrans; Carbazoles; Cell Fractionation; Cell Line; Cell Membrane; Endoplasmic Reticulum; Endosomes; Enzyme Inhibitors; Golgi Apparatus; Indoles; Isoenzymes; Lysophospholipids; Maleimides; Mice; Muscle, Skeletal; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Transport; rhoA GTP-Binding Protein; Sphingosine; Tetradecanoylphorbol Acetate

2000
Differential localization of protein kinase C isotypes in equine eosinophils and neutrophils.
    Journal of leukocyte biology, 2000, Volume: 68, Issue:4

    Topics: Animals; Brain; Cell Membrane; Cell Nucleus; Cytoplasmic Granules; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Horses; Indoles; Intracellular Membranes; Isoenzymes; Maleimides; Neutrophils; Organ Specificity; Protein Kinase C; Rats; Respiratory Burst; Staurosporine; Subcellular Fractions; Superoxides; Tetradecanoylphorbol Acetate

2000
AP-1 proteins mediate hyperglycemia-induced activation of the human TGF-beta1 promoter in mesangial cells.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:11

    Topics: Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glomerular Mesangium; Glucose; Humans; Hyperglycemia; Imidazoles; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Podophyllin; Podophyllotoxin; Promoter Regions, Genetic; Pyridines; RNA, Messenger; Sp1 Transcription Factor; Tetradecanoylphorbol Acetate; Tissue Distribution; Transcription Factor AP-1; Transforming Growth Factor beta; Transforming Growth Factor beta1

2000
High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells.
    Diabetes, 2000, Volume: 49, Issue:11

    Topics: Animals; Aorta; Blood Vessels; Cattle; Cells, Cultured; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Fatty Acids, Nonesterified; Glucose; Indoles; Maleimides; Muscle, Smooth, Vascular; NADPH Oxidases; Onium Compounds; Palmitic Acid; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

2000
Agonist-induced long-term desensitization of the human prostacyclin receptor.
    FEBS letters, 2000, Nov-10, Volume: 484, Issue:3

    Topics: beta-Adrenergic Receptor Kinases; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Fibroblasts; G-Protein-Coupled Receptor Kinase 5; Humans; Iloprost; Indoles; Kinetics; Maleimides; Phosphorylation; Polymerase Chain Reaction; Protein Kinase C; Protein Serine-Threonine Kinases; Receptors, Epoprostenol; Receptors, Prostaglandin; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection

2000
Stimulation of extracellular signal-regulated kinases and proliferation in rat osteoblastic cells by parathyroid hormone is protein kinase C-dependent.
    The Journal of biological chemistry, 2001, Mar-09, Volume: 276, Issue:10

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Blotting, Western; Cell Division; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Osteoblasts; Parathyroid Hormone; Peptides; Phosphorylation; Plasmids; Protein Kinase C; Proto-Oncogene Proteins p21(ras); Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection

2001
Serotonin transporter phosphorylation modulated by tetanus toxin.
    FEBS letters, 2000, Dec-08, Volume: 486, Issue:2

    Topics: Animals; Biological Transport; Brain; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Indoles; Isoenzymes; Isotope Labeling; Maleimides; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; Serine; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes; Tetanus Toxin; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases; Tyrosine

2000
Protein kinase C activation modulates pro- and anti-apoptotic signaling pathways.
    European journal of cell biology, 2000, Volume: 79, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Apoptotic Protease-Activating Factor 1; Blotting, Western; Bryostatins; Calcitriol; Caspases; Cell Cycle; Cell Differentiation; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Flow Cytometry; Humans; Indoles; Isoenzymes; Lactones; Macrolides; Maleimides; Membrane Glycoproteins; Protein Kinase C; Proteins; Proto-Oncogene Proteins c-bcl-2; Receptors, Tumor Necrosis Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha; U937 Cells

2000
Protein kinase C-alpha is an upstream activator of the IkappaB kinase complex in the TPA signal transduction pathway to NF-kappaB in U2OS cells.
    Cellular signalling, 2000, Volume: 12, Issue:11-12

    Topics: Butadienes; DNA-Binding Proteins; Enzyme Activation; Genes, Dominant; Humans; I-kappa B Kinase; I-kappa B Proteins; Indoles; Isoenzymes; Kinetics; Maleimides; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Nitriles; Protein Kinase C; Protein Kinase C-alpha; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2000
p53-independent elevation of p21 expression by PMA results from PKC-mediated mRNA stabilization.
    Biochemical and biophysical research communications, 2001, Jan-12, Volume: 280, Issue:1

    Topics: Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Genes, Reporter; Humans; Indoles; Kinetics; Luciferases; Maleimides; Okadaic Acid; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Suppressor Protein p53; U937 Cells

2001
Modulation of cyclin D1 and its signaling components by the phorbol ester TPA and the tyrosine phosphatase inhibitor vanadate.
    Journal of cellular physiology, 2001, Volume: 186, Issue:3

    Topics: Animals; Cell Division; Cell Line; Cell Membrane; Cyclin D1; Cytosol; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblasts; Flavonoids; Indoles; Isoenzymes; Kinetics; Maleimides; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Tyrosine Phosphatases; Signal Transduction; Tetradecanoylphorbol Acetate; Vanadates

2001
Characterization of the 5'-flanking region of the rat TIS11 gene.
    Molecular and cellular biochemistry, 2000, Volume: 214, Issue:1-2

    Topics: Animals; Cell Line; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genes, Immediate-Early; Genes, Reporter; Immediate-Early Proteins; Indoles; Luciferases; Maleimides; Mitogen-Activated Protein Kinase Kinases; PC12 Cells; Promoter Regions, Genetic; Protein Kinase C; Rats; Sequence Deletion; Tetradecanoylphorbol Acetate; Tristetraprolin

2000
The stimulation of MAP kinase by 1,25(OH)(2)-vitamin D(3) in skeletal muscle cells is mediated by protein kinase C and calcium.
    Molecular and cellular endocrinology, 2001, Feb-28, Volume: 173, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcitriol; Calcium; Calmodulin; Chick Embryo; Egtazic Acid; Enzyme Activation; Fluphenazine; Indoles; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Naphthalenes; Neomycin; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases; Verapamil

2001
Oxidized-LDL enhances coronary vasoconstriction by increasing the activity of protein kinase C isoforms alpha and epsilon.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Carbazoles; Coronary Vessels; Enzyme Activation; Enzyme Inhibitors; Fura-2; In Vitro Techniques; Indoles; Isoenzymes; Isometric Contraction; Lipoproteins, LDL; Male; Maleimides; Muscle, Smooth, Vascular; Potassium Chloride; Protein Kinase C; Serotonin; Subcellular Fractions; Swine; Tetradecanoylphorbol Acetate; Vasoconstriction; Verapamil

2001
Glycated serum albumin-induced vascular smooth muscle cell proliferation through activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by protein kinase C.
    Biochemical and biophysical research communications, 2001, Mar-09, Volume: 281, Issue:4

    Topics: Animals; Cell Division; Cell Line; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Indoles; Isoenzymes; Luciferases; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein Kinase C; Rats; Recombinant Fusion Proteins; Serum Albumin; Tetradecanoylphorbol Acetate; Transcriptional Activation

2001
Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
    Blood, 2001, Apr-01, Volume: 97, Issue:7

    Topics: Acetylcysteine; Amanitins; Aminoacetonitrile; Apoptosis; Benzoquinones; Bryostatins; Butadienes; Curcumin; Cysteine Endopeptidases; Dactinomycin; Diterpenes; Drug Synergism; Enzyme Activation; Flavonoids; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Lactams, Macrocyclic; Lactones; Macrolides; Maleimides; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Neoplasm Proteins; Nitriles; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Kinase C; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Quinones; Terpenes; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Type C Phospholipases; U937 Cells; Ubiquitins

2001
Modulation of rat erg1, erg2, erg3 and HERG K+ currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade.
    The Journal of physiology, 2001, Apr-01, Volume: 532, Issue:Pt 1

    Topics: Animals; Arachidonic Acid; Cation Transport Proteins; Cells, Cultured; Cholecystokinin; Colforsin; DNA-Binding Proteins; Enzyme Inhibitors; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Flavonoids; Humans; Indoles; Isoquinolines; Kinetics; Maleimides; Membrane Potentials; Membrane Transport Proteins; Patch-Clamp Techniques; Pituitary Gland, Anterior; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase Inhibitors; Protein Kinases; Rats; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Trans-Activators; Transcriptional Regulator ERG; Tyrphostins; Vasoactive Intestinal Peptide

2001
Differential effects of growth hormone and insulin-like growth factor I on human endothelial cell migration.
    American journal of physiology. Cell physiology, 2001, Volume: 280, Issue:5

    Topics: Cell Line; Cell Movement; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Epidermal Growth Factor; Human Growth Hormone; Humans; Indoles; Insulin-Like Growth Factor I; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Protein Kinase C; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate

2001
Altered expression of glutamate transporters under hypoxic conditions in vitro.
    Journal of neuroscience research, 2001, Apr-15, Volume: 64, Issue:2

    Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Carrier Proteins; Cell Death; Cell Hypoxia; Excitatory Amino Acid Transporter 2; Excitatory Amino Acid Transporter 3; Gene Expression Regulation; Glioma; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Hypothalamic Neoplasms; Indoles; Maleimides; Mice; Mitochondria; Nerve Tissue Proteins; Neuroglia; Neurons; Protein Kinase C; Rats; Receptors, Neurotransmitter; Recombinant Fusion Proteins; RNA, Messenger; Symporters; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

2001
Key role of PKC and Ca2+ in EGF protection of microtubules and intestinal barrier against oxidants.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 280, Issue:5

    Topics: Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cell Membrane Permeability; Cytosol; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Hydrogen Peroxide; Hypochlorous Acid; Indoles; Intestinal Mucosa; Isoenzymes; Maleimides; Microtubules; Models, Biological; Oxidants; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2001
Upregulation of p21(WAF1/CIP1) leads to morphologic changes and esterase activity in TPA-mediated differentiation of human prostate cancer cell line TSU-Pr1.
    Oncogene, 2001, Mar-08, Volume: 20, Issue:10

    Topics: Adenoviridae; Blotting, Northern; Blotting, Western; Carcinogens; Cell Differentiation; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Primers; Enzyme Inhibitors; Flavonoids; Humans; Indoles; Male; Maleimides; Mitogen-Activated Protein Kinases; Naphthol AS D Esterase; Prostatic Neoplasms; Protein Kinase C; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation

2001
Leukotriene D(4) affects localisation of vinculin in intestinal epithelial cells via distinct tyrosine kinase and protein kinase C controlled events.
    Journal of cell science, 2001, Volume: 114, Issue:Pt 10

    Topics: Actins; alpha Catenin; Cadherins; Carcinogens; Cell Adhesion; Cell Line; Cytoskeletal Proteins; Enzyme Inhibitors; Focal Adhesions; Humans; Indoles; Integrin beta1; Intestinal Mucosa; Leukotriene D4; Maleimides; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Tetradecanoylphorbol Acetate; Tyrosine; Vinculin

2001
Extracellular ATP stimulates an inhibitory pathway towards growth factor-induced cRaf-1 and MEKK activation in astrocyte cultures.
    Journal of neurochemistry, 2001, Volume: 77, Issue:4

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Fibroblast Growth Factor 2; Indoles; Kinetics; Maleimides; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Norepinephrine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Rats; Serotonin; Tetradecanoylphorbol Acetate

2001
TSH-induced differentiated functions correlate with enhancement of phosphotyrosine phosphatase activity in thyroid cells. Effect of phorbol 12-myristate 13-acetate.
    The Journal of endocrinology, 2001, Volume: 169, Issue:3

    Topics: Adenylyl Cyclases; Animals; Cell Culture Techniques; Cell Differentiation; Cyclic AMP; Enzyme Inhibitors; Indoles; Iodine; Maleimides; Protein Kinase C; Protein Tyrosine Phosphatases; Swine; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin

2001
Saturated non-esterified fatty acids stimulate de novo diacylglycerol synthesis and protein kinase c activity in cultured aortic smooth muscle cells.
    Diabetologia, 2001, Volume: 44, Issue:5

    Topics: Animals; Aorta; Arachidonic Acid; Cattle; Cells, Cultured; Coenzyme A Ligases; Diglycerides; Enzyme Inhibitors; Fatty Acids, Nonesterified; Indoles; Kinetics; Maleimides; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oleic Acid; Palmitic Acid; Protein Kinase C; Stearic Acids; Tetradecanoylphorbol Acetate; Triazenes

2001
Thrombin activates p38 mitogen-activated protein kinase in vascular smooth muscle cells.
    Life sciences, 2001, Mar-16, Volume: 68, Issue:17

    Topics: Animals; Aorta, Thoracic; Cell Division; Cells, Cultured; DNA; Enzyme Activation; Enzyme Inhibitors; Heterotrimeric GTP-Binding Proteins; Imidazoles; Indoles; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Rats; Tetradecanoylphorbol Acetate; Thrombin

2001
Down-modulation of L-selectin by lipopolysaccharide is not required for lipopolysaccharide-induced expression of CD14 in mouse bone marrow granulocytes.
    Infection and immunity, 2001, Volume: 69, Issue:7

    Topics: Animals; Bone Marrow Cells; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Granulocytes; Indoles; L-Selectin; Ligands; Lipopolysaccharide Receptors; Lipopolysaccharides; Maleimides; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Protein Binding; Protein Kinase C; Tetradecanoylphorbol Acetate

2001
Bradykinin induces protein kinase C-dependent activation of phospholipase D in A-431 cells.
    IUBMB life, 2001, Volume: 51, Issue:1

    Topics: Acetophenones; Benzopyrans; Bradykinin; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Immunoblotting; Indoles; Isoenzymes; Kinetics; Maleimides; Phospholipase D; Phospholipids; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2001
Insulin- and glucose-induced phosphorylation of the Na(+),K(+)-adenosine triphosphatase alpha-subunits in rat skeletal muscle.
    Endocrinology, 2001, Volume: 142, Issue:8

    Topics: Animals; Cell Membrane; Enzyme Inhibitors; Extracellular Space; Glucose; Indoles; Insulin; Male; Maleimides; Muscle, Skeletal; Phosphoamino Acids; Phosphorylation; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Tissue Distribution; Tyrosine

2001
Serotonin activation of the ERK pathway in Hermissenda: contribution of calcium-dependent protein kinase C.
    Journal of neurochemistry, 2001, Volume: 78, Issue:2

    Topics: Animals; Calcium; Carbazoles; Chelating Agents; Conditioning, Classical; Egtazic Acid; Enzyme Inhibitors; Indoles; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Mollusca; Phosphorylation; Serotonin; Tetradecanoylphorbol Acetate

2001
Pharmacological evidence for system-dependent involvement of protein kinase C isoenzymes in phorbol ester-suppressed gap junctional communication.
    Experimental cell research, 2001, Aug-15, Volume: 268, Issue:2

    Topics: Carbazoles; Cell Communication; Cells, Cultured; Connexin 43; Dose-Response Relationship, Drug; Gap Junctions; Indoles; Isoenzymes; Maleimides; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate

2001
Inorganic lead stimulates DNA synthesis in human astrocytoma cells: role of protein kinase Calpha.
    Journal of neurochemistry, 2001, Volume: 78, Issue:3

    Topics: Astrocytes; Astrocytoma; Carbachol; Carcinogens; Cell Cycle; Cell Division; Cholinergic Agonists; Culture Media, Serum-Free; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Immunoblotting; Indoles; Isoenzymes; Maleimides; Organometallic Compounds; Protein Kinase C; Protein Kinase C-alpha; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2001
Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes alpha and theta.
    European journal of biochemistry, 2001, Volume: 268, Issue:15

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Breast Neoplasms; Catalysis; Chloramphenicol O-Acetyltransferase; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Deletion; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; Indoles; Isoenzymes; Maleimides; Phenotype; Promoter Regions, Genetic; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-theta; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured

2001
Protein kinase epsilon dampens the secretory response of model intestinal epithelia during ischemia.
    Surgery, 2001, Volume: 130, Issue:2

    Topics: Biological Transport; Bryostatins; Carcinogens; Cell Hypoxia; Cell Line; Chlorides; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Intestinal Mucosa; Ischemia; Isoenzymes; Lactones; Macrolides; Maleimides; Mitogens; Protein Kinase C; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate

2001
Identification of protein kinase Calpha as an essential, but not sufficient, cytosolic factor for Ca2+-induced alpha- and dense-core granule secretion in platelets.
    The Journal of biological chemistry, 2001, Oct-19, Volume: 276, Issue:42

    Topics: Adenosine Triphosphate; Animals; Blood Platelets; Blotting, Western; Brain; Calcium; Chromatography, Gel; Cytosol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Indoles; Isoenzymes; Jurkat Cells; Maleimides; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Rats; Tetradecanoylphorbol Acetate

2001
Protein kinase C regulates the phosphorylation and cellular localization of occludin.
    The Journal of biological chemistry, 2001, Oct-19, Volume: 276, Issue:42

    Topics: Alkaline Phosphatase; Animals; Binding Sites; Calcium; Carcinogens; Cell Line; Cells, Cultured; Cytoplasm; Detergents; Diglycerides; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Indoles; Maleimides; Membrane Proteins; Mice; Microscopy, Fluorescence; Occludin; Octoxynol; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetradecanoylphorbol Acetate; Tight Junctions; Time Factors

2001
Mechanisms in fluoride-induced interleukin-8 synthesis in human lung epithelial cells.
    Toxicology, 2001, Oct-15, Volume: 167, Issue:2

    Topics: Androstadienes; Benzylamines; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Epithelial Cells; Flavonoids; Genistein; Humans; Indoles; Interleukin-8; Isoquinolines; Lung; Maleimides; Okadaic Acid; Pertussis Toxin; Protein Kinase C; Signal Transduction; Sodium Fluoride; Sulfonamides; Tetradecanoylphorbol Acetate; Vanadates; Virulence Factors, Bordetella; Wortmannin

2001
Docosahexaenoic acid modulates phorbol ester-induced activation of extracellular signal-regulated kinases 1 and 2 in NIH/3T3 cells.
    Lipids, 2001, Volume: 36, Issue:8

    Topics: 3T3 Cells; Animals; Cell Division; Docosahexaenoic Acids; Enzyme Activation; Enzyme Inhibitors; Indoles; Maleimides; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha

2001
Coupling strength between localized Ca(2+) transients and K(+) channels is regulated by protein kinase C.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:5

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Colon; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indoles; Inositol 1,4,5-Trisphosphate; Maleimides; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Muscle, Smooth; Potassium Channels; Protein Kinase C; Second Messenger Systems; Tetradecanoylphorbol Acetate

2001
Protein kinase C modulates telomerase activity in human cervical cancer cells.
    Experimental & molecular medicine, 2001, Sep-30, Volume: 33, Issue:3

    Topics: Alternative Splicing; Carbazoles; Catalytic Domain; Enzyme Inhibitors; Female; HeLa Cells; Humans; Indoles; Maleimides; Protein Kinase C; RNA, Messenger; Telomerase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2001
TNF-alpha enhances intracellular glucocorticoid availability.
    FEBS letters, 2001, Nov-02, Volume: 507, Issue:3

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Cells, Cultured; Colforsin; Corticosterone; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glucocorticoids; Glucose; Hydroxysteroid Dehydrogenases; Imidazoles; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Pyridines; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2001
Enhancement of phospholipase D activity by overexpression of amyloid precursor protein in P19 mouse embryonic carcinoma cells.
    Neuroscience letters, 2001, Nov-27, Volume: 315, Issue:3

    Topics: Amyloid beta-Protein Precursor; Animals; Cell Differentiation; Enzyme Activation; Enzyme Inhibitors; Indoles; Maleimides; Mice; Neurons; Peptide Fragments; Phospholipase D; Protein Kinase C; Reference Values; Tetradecanoylphorbol Acetate; Transfection; Tretinoin; Tumor Cells, Cultured

2001
Phosphorylation-dependent regulation of phospholipase D2 by protein kinase C delta in rat Pheochromocytoma PC12 cells.
    The Journal of biological chemistry, 2002, Mar-08, Volume: 277, Issue:10

    Topics: Acetophenones; Adenoviridae; Animals; Benzopyrans; Bradykinin; Cell Membrane; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunoblotting; Immunohistochemistry; Indoles; Isoenzymes; Maleimides; Microscopy, Fluorescence; Mutation; PC12 Cells; Peptide Mapping; Phospholipase D; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Transport; Rats; Tetradecanoylphorbol Acetate; Time Factors; Up-Regulation

2002
The P2X(7) receptor-mediated phospholipase D activation is regulated by both PKC-dependent and PKC-independent pathways in a rat brain-derived Type-2 astrocyte cell line, RBA-2.
    Cellular signalling, 2002, Volume: 14, Issue:1

    Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Indoles; Kinetics; Maleimides; Phospholipase D; Protein Kinase C; Protein-Tyrosine Kinases; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X7; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases

2002
Protein Kinase C is a mediator of the synthesis and secretion of osteoprotegerin in osteoblast-like cells.
    Biochemical and biophysical research communications, 2002, Jan-11, Volume: 290, Issue:1

    Topics: Animals; Antibodies; Blotting, Northern; Blotting, Western; Cell Line; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Glycoproteins; Humans; Indoles; Maleimides; Osteoblasts; Osteoprotegerin; Promoter Regions, Genetic; Protein Kinase C; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2002
Activation of Erk1/Erk2 and transiently increased p53 levels together may account for p21 expression associated with phorbol ester-induced transient growth inhibition in HepG2 cells.
    Cellular signalling, 2002, Volume: 14, Issue:2

    Topics: Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Kinase C; Proto-Oncogene Proteins c-raf; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
Protein kinase C-dependent, CCAAT/enhancer-binding protein beta-mediated expression of insulin-like growth factor I gene.
    The Journal of biological chemistry, 2002, May-03, Volume: 277, Issue:18

    Topics: Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Insulin-Like Growth Factor I; Maleimides; Promoter Regions, Genetic; Protein Kinase C; Protein Processing, Post-Translational; Recombinant Fusion Proteins; RNA, Messenger; Serine; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured

2002
Effect of wortmannin and phorbol ester on Paramecium fluid-phase uptake in the presence of transferrin.
    European journal of histochemistry : EJH, 2001, Volume: 45, Issue:4

    Topics: Androstadienes; Animals; Biomarkers; Endocytosis; Endosomes; Enzyme Activation; Indoles; Isoquinolines; Maleimides; Paramecium; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Tetradecanoylphorbol Acetate; Transferrin; Wortmannin

2001
FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway.
    Biochemical and biophysical research communications, 2002, May-17, Volume: 293, Issue:4

    Topics: Acetophenones; Benzopyrans; Carbazoles; Collagenases; Enzyme Inhibitors; Fibroblast Growth Factor 2; Genes, Dominant; Humans; Indoles; Maleimides; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; ras Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

2002
Blocking NF-kappaB activation in Jurkat leukemic T cells converts the survival agent and tumor promoter PMA into an apoptotic effector.
    Oncogene, 2002, May-09, Volume: 21, Issue:20

    Topics: Apoptosis; Carbazoles; Caspase 8; Caspase 9; Caspases; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Gene Expression Regulation, Leukemic; Humans; I-kappa B Proteins; Indoles; Isoenzymes; Jurkat Cells; Maleimides; Membrane Glycoproteins; Neoplasm Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Protein Kinase C; Recombinant Fusion Proteins; Sequence Deletion; Tetradecanoylphorbol Acetate

2002
Phorbol myristate acetate induces ruffling of the acrosome of human sperm.
    Fertility and sterility, 2002, Volume: 78, Issue:1

    Topics: Acrosome; Acrosome Reaction; Actins; Cells, Cultured; Cytochalasin B; Cytochalasin D; Enzyme Inhibitors; Female; Humans; Indoles; Male; Maleimides; Microscopy, Electron; Microscopy, Electron, Scanning; Oocytes; Polymers; Protein Kinase C; Pyrimidine Nucleosides; Tetradecanoylphorbol Acetate; Zona Pellucida

2002
Protein kinase C regulates endocytosis and recycling of E-cadherin.
    American journal of physiology. Cell physiology, 2002, Volume: 283, Issue:2

    Topics: Actins; Adherens Junctions; Animals; Cadherins; Cell Adhesion; Cell Line; Cell Membrane; Dogs; Endocytosis; Endosomes; Enzyme Inhibitors; Indoles; Maleimides; Polymers; Protein Kinase C; Tetradecanoylphorbol Acetate

2002
Excitation of smooth muscles isolated from the guinea-pig gastric antrum in response to depolarization.
    The Journal of physiology, 2002, Aug-15, Volume: 543, Issue:Pt 1

    Topics: Acetylcholine; Alkaloids; Animals; Benzophenanthridines; Boron Compounds; Calcium; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carcinogens; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials; Guinea Pigs; Indoles; Ionophores; Lanthanum; Male; Maleimides; Muscle, Smooth; Phenanthridines; Protein Kinase C; Pyloric Antrum; Tetradecanoylphorbol Acetate; Thapsigargin

2002
Phosphospecific site tyrosine phosphorylation of p125FAK and proline-rich kinase 2 is differentially regulated by cholecystokinin receptor type A activation in pancreatic acini.
    The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21

    Topics: Animals; Binding Sites; Calcium; Cholecystokinin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Hydrolysis; Indoles; Inositol Phosphates; Kinetics; Male; Maleimides; Pancreas; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Tetradecanoylphorbol Acetate; Thapsigargin; Type C Phospholipases

2003
BCR targets cyclin D2 via Btk and the p85alpha subunit of PI3-K to induce cell cycle progression in primary mouse B cells.
    Oncogene, 2003, Apr-17, Volume: 22, Issue:15

    Topics: Adaptor Proteins, Signal Transducing; Agammaglobulinaemia Tyrosine Kinase; Amides; Animals; Antibodies, Anti-Idiotypic; Apoptosis; B-Lymphocytes; Calcium Signaling; Carrier Proteins; Cell Cycle; Chromones; Class Ib Phosphatidylinositol 3-Kinase; Crosses, Genetic; Cyclin D2; Cyclins; Enzyme Inhibitors; Female; Imidazoles; Immunologic Deficiency Syndromes; Indoles; Ionomycin; Isoenzymes; Macromolecular Substances; Male; Maleimides; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Mutant Strains; Models, Immunological; Morpholines; Nitriles; Phenotype; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Protein Interaction Mapping; Protein Processing, Post-Translational; Protein Subunits; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate; Type C Phospholipases

2003
Effect of protein kinase C activation and inhibition on rat hepatic stellate cell activation.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:4

    Topics: Actins; Alkaloids; Animals; Benzophenanthridines; Cell Division; Cells, Cultured; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; In Vitro Techniques; Indoles; Liver; Male; Maleimides; Phenanthridines; Phorbol Esters; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate

2003
Modification of intracellular free calcium in cultured A10 vascular smooth muscle cells by exogenous phosphatidic acid.
    Biochemical pharmacology, 2003, Jun-15, Volume: 65, Issue:12

    Topics: Animals; Boron Compounds; Calcium; Carbamates; Cells, Cultured; Diltiazem; Drug Interactions; Egtazic Acid; Indoles; Macrocyclic Compounds; Maleimides; Muscle, Smooth, Vascular; Oxazoles; Pertussis Toxin; Phenylcarbamates; Phosphatidic Acids; Rats; Tetradecanoylphorbol Acetate; Thapsigargin; Verapamil

2003
Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta-cells (INS-1).
    Journal of molecular endocrinology, 2003, Volume: 30, Issue:3

    Topics: Acetophenones; Benzopyrans; Cell Line; Enzyme Activation; Enzyme Inhibitors; Fatty Acids, Nonesterified; Humans; Indoles; Insulin-Like Growth Factor I; Islets of Langerhans; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tetradecanoylphorbol Acetate

2003
Recovery of gap junctional intercellular communication after phorbol ester treatment requires proteasomal degradation of protein kinase C.
    Carcinogenesis, 2003, Volume: 24, Issue:7

    Topics: Animals; Blotting, Western; Cell Communication; Cells, Cultured; Connexin 43; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Gap Junctions; Indoles; Isoenzymes; Leupeptins; Liver; Maleimides; Multienzyme Complexes; Peptide Hydrolases; Proteasome Endopeptidase Complex; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

2003
Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling.
    The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptosis Regulatory Proteins; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspase 3; Caspase 8; Caspase 9; Caspases; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Fas-Associated Death Domain Protein; HeLa Cells; Humans; I-kappa B Proteins; Indoles; Maleimides; Membrane Glycoproteins; Mitochondria; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphatidylserines; Phosphorylation; Protein Kinase C; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Signal Transduction; Tetradecanoylphorbol Acetate; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2003
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells

2003
15-Deoxy-Delta12,14-prostaglandin J2 regulates endogenous Cot MAPK kinase kinase 1 activity induced by lipopolysaccharide.
    The Journal of biological chemistry, 2003, Dec-26, Volume: 278, Issue:52

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Carcinogens; Cell Division; Cell Line; Enzyme Activation; Enzyme Inhibitors; Fibrinolytic Agents; Gene Expression Regulation, Enzymologic; Indoles; Ligands; Lipopolysaccharides; Macrophages; Maleimides; MAP Kinase Kinase Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Precipitin Tests; Prostaglandin D2; Protein Isoforms; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; RNA, Messenger; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazolidinediones; Time Factors

2003
Activation of P2X7 purinoceptor-stimulated TGF-beta 1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line, RBA-2.
    Cellular signalling, 2003, Volume: 15, Issue:12

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Astrocytes; Blotting, Northern; Blotting, Western; Brain; Carbazoles; Cell Line; Dose-Response Relationship, Drug; Flavonoids; Gene Expression; Indoles; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Transforming Growth Factor beta1

2003
Diacylglycerols containing Omega 3 and Omega 6 fatty acids bind to RasGRP and modulate MAP kinase activation.
    The Journal of biological chemistry, 2004, Jan-09, Volume: 279, Issue:2

    Topics: Animals; Binding, Competitive; Brain; Diglycerides; DNA-Binding Proteins; DNA, Complementary; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Fatty Acids; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Guanine Nucleotide Exchange Factors; Humans; Immunoblotting; Indoles; Inhibitory Concentration 50; Jurkat Cells; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Plasmids; Protein Binding; Rats; Tetradecanoylphorbol Acetate; Time Factors; Transfection

2004
Ca2+-dependent protein kinase C isoforms induce cholestasis in rat liver.
    The Journal of biological chemistry, 2004, Mar-12, Volume: 279, Issue:11

    Topics: Animals; Bacterial Proteins; Bile; Biological Transport; Blotting, Western; Calcium; Carbazoles; Cell Line; Cell Membrane; Cells, Cultured; Cholestasis; Cloning, Molecular; Densitometry; Detergents; Dose-Response Relationship, Drug; Enzyme Activation; Hepatocytes; Humans; Indoles; Liver; Luminescent Proteins; Male; Maleimides; Microscopy, Confocal; Models, Biological; Perfusion; Phorbol Esters; Polymerase Chain Reaction; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Wistar; Signal Transduction; Taurocholic Acid; Tetradecanoylphorbol Acetate; Time Factors; Transfection

2004
Cooperation between PKC-alpha and PKC-epsilon in the regulation of JNK activation in human lung cancer cells.
    Cellular signalling, 2004, Volume: 16, Issue:4

    Topics: Animals; Carbazoles; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Membrane; Cytoplasm; Humans; Indoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; Maleimides; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; rac1 GTP-Binding Protein; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2004
Regulation of phospholipase D2 activity by protein kinase C alpha.
    The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21

    Topics: Animals; COS Cells; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Indoles; Maleimides; Phospholipase D; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Serine; Subcellular Fractions; Tetradecanoylphorbol Acetate; Threonine; Time Factors; Transfection

2004
Protein kinase C activation by Helicobacter pylori in human gastric epithelial cells limits interleukin-8 production through suppression of extracellular signal-regulated kinase.
    Journal of pharmacological sciences, 2004, Volume: 94, Issue:3

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion Molecules; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Gastric Mucosa; Helicobacter pylori; Humans; I-kappa B Kinase; Indoles; Interleukin-8; Maleimides; Methods; Naphthalenes; Protein Kinase C; Protein Serine-Threonine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2004
Induction of manganese-superoxide dismutase by YS 51, a synthetic 1-(beta-naphtylmethyl)6,7-dihydroxy- 1,2,3,4-tetrahydroisoquinoline alkaloid: implication for anti-inflammatory actions.
    Pharmacology, 2004, Volume: 71, Issue:2

    Topics: Animals; Blotting, Northern; Curcumin; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Flavonoids; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phorbol Esters; Phosphorylation; Pulmonary Artery; Pyridines; RNA, Messenger; Sheep; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tetrahydroisoquinolines; Tumor Necrosis Factor-alpha

2004
Protein kinase C activity regulates the onset of anaphase I in mouse oocytes.
    Biology of reproduction, 2004, Volume: 71, Issue:5

    Topics: Anaphase; Animals; Dose-Response Relationship, Drug; Embryonic Development; Enzyme Activation; Enzyme Inhibitors; Female; Fertilization in Vitro; Indoles; Maleimides; Metaphase; Mice; Mice, Inbred Strains; Oocytes; Protein Kinase C; Tetradecanoylphorbol Acetate

2004
Activation of protein kinase C antagonizes the opioid inhibition of calcium current in rat spinal dorsal horn neurons.
    Brain research, 2004, Aug-13, Volume: 1017, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Colforsin; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Activation; Enzyme Inhibitors; Female; Indoles; Isoquinolines; Male; Maleimides; Membrane Potentials; Narcotics; Patch-Clamp Techniques; Posterior Horn Cells; Potassium Channel Blockers; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetradecanoylphorbol Acetate; Tetraethylammonium; Tetrodotoxin

2004
Activation of second messenger-dependent protein kinases induces muscarinic acetylcholine receptor desensitization in rat thyroid epithelial cells.
    Molecular and cellular endocrinology, 2004, Aug-31, Volume: 223, Issue:1-2

    Topics: Animals; Arsenicals; Calcium; Calcium Channels; Carbachol; Colforsin; Cyclic AMP-Dependent Protein Kinases; Endocytosis; Epithelial Cells; Indoles; Maleimides; Muscarinic Agonists; Protein Kinase C; Rats; Rats, Inbred F344; Receptors, Muscarinic; Second Messenger Systems; Sucrose; Tetradecanoylphorbol Acetate; Thyroid Gland

2004
Ghrelin exerts a proliferative effect on a rat pituitary somatotroph cell line via the mitogen-activated protein kinase pathway.
    European journal of endocrinology, 2004, Volume: 151, Issue:2

    Topics: Androstadienes; Animals; Butadienes; Carcinogens; Cell Division; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ghrelin; Indoles; Maleimides; MAP Kinase Signaling System; Nitriles; Peptide Hormones; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pituitary Gland; Pituitary Neoplasms; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Tyrphostins; Wortmannin

2004
IkappaBalpha (inhibitory kappaBalpha) identified as labile repressor of MnSOD (manganese superoxide dismutase) expression.
    The Biochemical journal, 2004, Dec-15, Volume: 384, Issue:Pt 3

    Topics: Cell Line; Cycloheximide; DNA; Down-Regulation; Enhancer Elements, Genetic; Gene Expression Regulation, Enzymologic; Humans; I-kappa B Proteins; Indoles; Introns; Isoenzymes; Maleimides; NF-kappa B; NF-KappaB Inhibitor alpha; Protein Binding; Protein Biosynthesis; Protein Kinase C; Protein Processing, Post-Translational; Protein Transport; Repressor Proteins; RNA, Messenger; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1

2004
Role of protein kinase C delta in reactivation of Kaposi's sarcoma-associated herpesvirus.
    Journal of virology, 2004, Volume: 78, Issue:18

    Topics: Acetophenones; Benzopyrans; Cell Line; Enzyme Inhibitors; Herpesvirus 8, Human; Humans; Indoles; Maleimides; Protein Kinase C; Protein Kinase C-delta; Tetradecanoylphorbol Acetate; Virus Activation; Virus Latency

2004
Alterations in receptor expression or agonist concentration change the pathways gastrin-releasing peptide receptor uses to regulate extracellular signal-regulated kinase.
    Molecular pharmacology, 2004, Volume: 66, Issue:6

    Topics: 3T3 Cells; Animals; Bombesin; Cell Line; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Indoles; Maleimides; Mice; Microscopy, Confocal; Protein Transport; Receptors, Bombesin; Tetradecanoylphorbol Acetate

2004
Exploring the pharmacology of the leukotriene B4 receptor BLT1, without the confounding effects of BLT2.
    European journal of pharmacology, 2004, Sep-19, Volume: 499, Issue:1-2

    Topics: Boron Compounds; Calcium; Calcium Channel Blockers; Cytosol; Dantrolene; Dose-Response Relationship, Drug; Estrenes; Fatty Alcohols; Glycols; HeLa Cells; Humans; Imidazoles; Indoles; Intracellular Space; Maleimides; Nickel; Nifedipine; Plasmids; Propranolol; Protein Kinase Inhibitors; Pyrrolidinones; Receptors, Leukotriene B4; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection

2004
Possible involvement of protein kinase C activation in differentiation of human umbilical vein endothelium-derived cell into smooth muscle-like cell.
    Biology of the cell, 2004, Volume: 96, Issue:7

    Topics: Carbazoles; Carcinogens; Cell Differentiation; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Maleimides; Myocytes, Smooth Muscle; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Umbilical Veins

2004
Differential in vitro neurotoxicity of the flame retardant PBDE-99 and of the PCB Aroclor 1254 in human astrocytoma cells.
    Toxicology letters, 2004, Dec-01, Volume: 154, Issue:1-2

    Topics: Apoptosis; Astrocytes; Astrocytoma; Cell Line, Tumor; Cell Survival; Chlorodiphenyl (54% Chlorine); Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Flame Retardants; Formazans; Halogenated Diphenyl Ethers; Humans; Indoles; Isoenzymes; L-Lactate Dehydrogenase; Maleimides; Phenyl Ethers; Protein Kinase C; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Trypan Blue; Tumor Suppressor Protein p53

2004
Protein kinase C activation promotes the internalization of the human cationic amino acid transporter hCAT-1. A new regulatory mechanism for hCAT-1 activity.
    The Journal of biological chemistry, 2004, Dec-24, Volume: 279, Issue:52

    Topics: Animals; Biotinylation; Cationic Amino Acid Transporter 1; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Glioblastoma; Green Fluorescent Proteins; Homeostasis; Humans; Indoles; Maleimides; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Oocytes; Phosphorylation; Protein Kinase C; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Xenopus laevis

2004
Histamine reduces gap junctional communication of human tonsil high endothelial cells in culture.
    Microvascular research, 2004, Volume: 68, Issue:3

    Topics: Cells, Cultured; Chlorpheniramine; Coloring Agents; Connexin 43; Cyclic AMP; Cyclooxygenase Inhibitors; Cytoskeleton; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Gap Junctions; Histamine; Humans; Immunoblotting; Indoles; Indomethacin; Inflammation; Ionophores; Maleimides; Microscopy, Fluorescence; Palatine Tonsil; Phalloidine; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Time Factors

2004
Connexin43 synthesis, phosphorylation, and degradation in regulation of transient inhibition of gap junction intercellular communication by the phorbol ester TPA in rat liver epithelial cells.
    Experimental cell research, 2005, Jan-15, Volume: 302, Issue:2

    Topics: Animals; Blotting, Western; Carcinogens; Cell Communication; Cell Line; Cell Line, Tumor; Connexin 43; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Fluorescent Dyes; Gap Junctions; Image Processing, Computer-Assisted; Indoles; Isoquinolines; Liver; Maleimides; MAP Kinase Signaling System; Phosphorylation; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors

2005
Protein kinase C modulates agonist-sensitive release of Ca2+ from internal stores in HEK293 cells overexpressing the calcium sensing receptor.
    The Journal of biological chemistry, 2005, Feb-11, Volume: 280, Issue:6

    Topics: Calcium; Carbazoles; Cations; Cell Line; Culture Media, Serum-Free; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Humans; Immunoblotting; Indoles; Maleimides; Neomycin; Protein Isoforms; Protein Kinase C; Protein Kinase C-epsilon; Receptors, Calcium-Sensing; Signal Transduction; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors

2005
Dopamine and norepinephrine transporter-dependent c-Fos production in vitro: relevance to neuroadaptation.
    Journal of neuroscience methods, 2005, Apr-15, Volume: 143, Issue:1

    Topics: Adaptation, Physiological; Brain Chemistry; Cell Line; Dopamine; Dopamine Agonists; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Maleimides; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-fos; Symporters; Tetradecanoylphorbol Acetate

2005
P2Y2 nucleotide receptors enhance alpha-secretase-dependent amyloid precursor protein processing.
    The Journal of biological chemistry, 2005, May-13, Volume: 280, Issue:19

    Topics: ADAM Proteins; ADAM17 Protein; Amino Acid Chloromethyl Ketones; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Blotting, Western; Butadienes; Calcium; Cell Line, Tumor; Central Nervous System; Chelating Agents; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Endopeptidases; Furin; Humans; Indoles; Maleimides; MAP Kinase Signaling System; Metalloendopeptidases; Nitriles; Phorbol Esters; Protein Kinase C; Protein Structure, Tertiary; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Small Interfering; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Uridine Triphosphate

2005
Artocarpol A stimulation of superoxide anion generation in neutrophils involved the activation of PLC, PKC and p38 mitogen-activated PK signaling pathways.
    British journal of pharmacology, 2005, Volume: 145, Issue:4

    Topics: Animals; Butadienes; Calcium; Cell-Free System; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; Immunoblotting; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Type C Phospholipases

2005
The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes.
    British journal of pharmacology, 2005, Volume: 145, Issue:4

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Cell Line; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Estrenes; Humans; I-kappa B Kinase; Indoles; Keratinocytes; Maleimides; Mitogen-Activated Protein Kinases; NF-kappa B; Oligonucleotides; Phosphodiesterase Inhibitors; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Pyrrolidinones; Receptor, PAR-2; Signal Transduction; Tacrolimus; Tetradecanoylphorbol Acetate; Trypsin; Type C Phospholipases

2005
Effect of protein kinase C activation on intracellular Ca2+ signaling and integrity of intestinal epithelial cells.
    European journal of pharmacology, 2005, Jul-25, Volume: 518, Issue:1

    Topics: Acetophenones; Animals; Benzopyrans; Calcium; Calcium Channel Blockers; Calcium Signaling; Carbazoles; Cell Line; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Indoles; Intestinal Mucosa; Intracellular Space; Maleimides; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate; Verapamil

2005
Acoustic environment determines phosphorylation state of the Kv3.1 potassium channel in auditory neurons.
    Nature neuroscience, 2005, Volume: 8, Issue:10

    Topics: Acoustic Stimulation; Action Potentials; Animals; Animals, Newborn; Brain Stem; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Inhibitors; Functional Laterality; Gene Expression Regulation; Immunohistochemistry; In Vitro Techniques; Indoles; Maleimides; Neurons; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate

2005
Tumor necrosis factor-alpha activates the extrapituitary PRL promoter in myeloid leukemic cells.
    Journal of neuroimmunology, 2006, Volume: 172, Issue:1-2

    Topics: Analysis of Variance; Cell Line; Drug Interactions; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Indoles; Leukemia, Myeloid; Maleimides; Mutagenesis; Prolactin; Promoter Regions, Genetic; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha

2006
Protein kinase C negatively regulates Akt activity and modifies UVC-induced apoptosis in mouse keratinocytes.
    The Journal of biological chemistry, 2006, Feb-10, Volume: 281, Issue:6

    Topics: Adenoviridae; Animals; Apoptosis; Cells, Cultured; Immunoblotting; Immunoprecipitation; Indoles; Insulin-Like Growth Factor I; Keratinocytes; Maleimides; Mice; Phosphoprotein Phosphatases; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Protein Phosphatase 2; Protein Transport; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Skin; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays

2006
Regulation of protein kinase C delta by phorbol ester, endothelin-1, and platelet-derived growth factor in cardiac myocytes.
    The Journal of biological chemistry, 2006, Mar-31, Volume: 281, Issue:13

    Topics: Animals; Animals, Newborn; Cell Culture Techniques; Cell Extracts; Cells, Cultured; Chromatography, Gel; Chromones; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Immunoblotting; Indoles; Maleimides; Morpholines; Myocytes, Cardiac; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinase C-delta; Pyrimidines; Rats; Rats, Sprague-Dawley; Solubility; Tetradecanoylphorbol Acetate; Time Factors

2006
Regulation of vascular smooth muscle proliferation and migration by beta2-chimaerin, a non-protein kinase C phorbol ester receptor.
    International journal of molecular medicine, 2006, Volume: 17, Issue:4

    Topics: Animals; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cells, Cultured; Gene Expression; GTPase-Activating Proteins; Humans; Immunohistochemistry; Indoles; Infant, Newborn; Maleimides; Mitogens; Muscle, Smooth, Vascular; Neoplasm Proteins; Platelet-Derived Growth Factor; Protein Kinase C; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate

2006
Bradykinin augments EGF-induced airway smooth muscle proliferation by activation of conventional protein kinase C isoenzymes.
    European journal of pharmacology, 2006, Mar-27, Volume: 535, Issue:1-3

    Topics: Animals; Bradykinin; Carbazoles; Cattle; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Indoles; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Smooth Muscle; Protein Kinase C; Receptor, Bradykinin B2; Tetradecanoylphorbol Acetate; Thymidine; Trachea; Tritium

2006
Mechanism of gonadotropin-releasing hormone (GnRH)-I and -II-induced cell growth inhibition in ovarian cancer cells: role of the GnRH-I receptor and protein kinase C pathway.
    Endocrine-related cancer, 2006, Volume: 13, Issue:1

    Topics: Adenocarcinoma; Cell Proliferation; Enzyme Activation; Enzyme Inhibitors; Female; Gonadotropin-Releasing Hormone; Humans; Indoles; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oligopeptides; Ovarian Neoplasms; Protein Kinase C; Receptors, LHRH; RNA, Small Interfering; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured

2006
Stimulation of cyclic AMP production by the Caenorhabditis elegans muscarinic acetylcholine receptor GAR-3 in Chinese hamster ovary cells.
    Archives of biochemistry and biophysics, 2006, Jun-15, Volume: 450, Issue:2

    Topics: Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcium; Carbachol; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; Indoles; Maleimides; Muscarinic Agonists; Muscarinic Antagonists; Pertussis Toxin; Protein Isoforms; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate

2006
Calcium channel and glutamate receptor activities regulate actin organization in salamander retinal neurons.
    The Journal of physiology, 2006, Sep-01, Volume: 575, Issue:Pt 2

    Topics: Actins; Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium Channels, L-Type; Carcinogens; Cell Survival; Electrophysiology; Enzyme Inhibitors; Glutamic Acid; Indoles; Maleimides; Neurons, Afferent; Phenanthridines; Potassium; Protein Kinase C; Receptors, Glutamate; Retinal Ganglion Cells; Tetradecanoylphorbol Acetate; Urodela

2006
Increase of C-type natriuretic peptide expression by serum and platelet-derived growth factor-BB in human aortic smooth muscle cells is dependent on protein kinase C activation.
    Endocrinology, 2006, Volume: 147, Issue:9

    Topics: Animals; Aorta; Becaplermin; Blood; Cells, Cultured; Culture Media; Endothelial Cells; Enzyme Activation; Gene Expression; Genistein; Humans; Indoles; Maleimides; Muscle, Smooth, Vascular; Natriuretic Peptide, C-Type; Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Rats; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Species Specificity; Tetradecanoylphorbol Acetate; Tyrphostins

2006
Role of kinases and G-proteins in the hyposmotic stimulation of cardiac IKs.
    Biochimica et biophysica acta, 2006, Volume: 1758, Issue:10

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Chromans; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cytochalasin D; Cytoskeleton; GTP-Binding Proteins; Guinea Pigs; Indoles; Isoquinolines; KCNQ1 Potassium Channel; Maleimides; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Osmotic Pressure; Phosphatidylinositol 3-Kinases; Potassium Channels; Protein Kinase C; Protein-Tyrosine Kinases; Sulfonamides; Tetradecanoylphorbol Acetate; Tyrphostins

2006
Protein kinase Cbeta isoform down-regulates the expression of MDR3 P-glycoprotein in human Chang liver cells.
    Biochimica et biophysica acta, 2006, Volume: 1760, Issue:10

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Carbazoles; Cells, Cultured; Down-Regulation; Humans; Indoles; Isoenzymes; Liver; Maleimides; Protein Kinase C; Protein Kinase C beta; Tetradecanoylphorbol Acetate

2006
On the mechanisms of 12-O-tetradecanoylphorbol-13-acetate-induced growth arrest in pancreatic cancer cells.
    Pancreas, 2006, Volume: 33, Issue:2

    Topics: Cell Division; Cell Line, Tumor; Cell Proliferation; Cyclin A; Cyclin B; Cyclin B1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Flavonoids; G2 Phase; Gene Expression Regulation, Neoplastic; Humans; Indoles; Maleimides; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pancreatic Neoplasms; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; RNA, Messenger; Tetradecanoylphorbol Acetate

2006
Protein kinase C cross-talk with gonadotrope progesterone receptor is involved in GnRH-induced LH secretion.
    Journal of physiology and biochemistry, 2006, Volume: 62, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bodily Secretions; Cells, Cultured; Chelating Agents; Colforsin; Egtazic Acid; Enzyme Inhibitors; Female; Gonadotropin-Releasing Hormone; Imines; Indoles; Ionomycin; Luteinizing Hormone; Maleimides; Mifepristone; Nifedipine; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Receptors, Progesterone; Signal Transduction; Tetradecanoylphorbol Acetate

2006
Hydrogen peroxide-induced arachidonic acid release in L929 cells; roles of Src, protein kinase C and cytosolic phospholipase A2alpha.
    European journal of pharmacology, 2006, Sep-28, Volume: 546, Issue:1-3

    Topics: Animals; Arachidonic Acid; Calcimycin; Calcium; Cell Line, Tumor; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Group IV Phospholipases A2; Humans; Hydrogen Peroxide; Indoles; Ionophores; Maleimides; Mice; Phospholipases A; Protein Kinase C; Protein Kinase C-alpha; Protein Transport; Pyrimidines; Pyrrolidines; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate; Transfection

2006
The sarcoplasmic-endoplasmic reticulum Ca2+ ATPase 2b regulates the Ca2+ transients elicited by P2Y2 activation in PC Cl3 thyroid cells.
    The Journal of endocrinology, 2006, Volume: 190, Issue:3

    Topics: Adenosine Triphosphate; Animals; Barium; Biological Transport, Active; Calcium; Carbazoles; Cell Line; Enzyme Activation; Indoles; Maleimides; Manganese; Microscopy, Fluorescence; Protein Kinase C; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tetradecanoylphorbol Acetate; Thapsigargin; Thyroid Gland; Uridine Triphosphate

2006
Phospholipase A2-independent Ca2+ entry and subsequent apoptosis induced by melittin in human MG63 osteosarcoma cells.
    Life sciences, 2007, Jan-02, Volume: 80, Issue:4

    Topics: Apoptosis; Calcium; Calcium Channels, L-Type; Cell Line, Tumor; Cell Survival; Egtazic Acid; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Indoles; Maleimides; Melitten; Osteoblasts; Osteosarcoma; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate

2007
TNF-alpha decreases hsp 27 in human blood mononuclear cells: involvement of protein kinase c.
    Life sciences, 2006, Dec-23, Volume: 80, Issue:3

    Topics: Carcinogens; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Indoles; Leukocytes, Mononuclear; Maleimides; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2006
Role of ROS and MAPK in TPA-induced ICAM-1 expression in the myeloid ML-1 cell line.
    Journal of cellular biochemistry, 2007, Mar-01, Volume: 100, Issue:4

    Topics: Blotting, Western; Butadienes; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Indoles; Intercellular Adhesion Molecule-1; Leukemia, Myeloid; Maleimides; Mitogen-Activated Protein Kinases; Models, Biological; NF-kappa B; Nitriles; Oligonucleotide Array Sequence Analysis; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Sulfones; Tetradecanoylphorbol Acetate

2007
Sustained activation of proton channels and NADPH oxidase in human eosinophils and murine granulocytes requires PKC but not cPLA2 alpha activity.
    The Journal of physiology, 2007, Mar-01, Volume: 579, Issue:Pt 2

    Topics: Animals; Arachidonic Acids; Carcinogens; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Granulocytes; Group IV Phospholipases A2; Humans; Indoles; Ion Channels; Maleimides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Okadaic Acid; Phospholipases A; Protein Kinase C; Protons; Signal Transduction; Tetradecanoylphorbol Acetate

2007
Alpha1-adrenergic receptor stimulation induces the expression of receptor activator of nuclear factor kappaB ligand gene via protein kinase C and extracellular signal-regulated kinase pathways in MC3T3-E1 osteoblast-like cells.
    Archives of oral biology, 2007, Volume: 52, Issue:8

    Topics: 3T3 Cells; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blotting, Western; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Indoles; Maleimides; Mice; Osteoblasts; Phenylephrine; Prazosin; Propranolol; Protein Kinase C; Receptor Activator of Nuclear Factor-kappa B; Receptors, Adrenergic, alpha-1; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Yohimbine

2007
Stimulatory action of protein kinase C(epsilon) isoform on the slow component of delayed rectifier K+ current in guinea-pig atrial myocytes.
    British journal of pharmacology, 2007, Volume: 150, Issue:8

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Delayed Rectifier Potassium Channels; Dose-Response Relationship, Drug; Enzyme Activation; Guinea Pigs; Heart Atria; In Vitro Techniques; Indoles; Isoenzymes; Maleimides; Membrane Potentials; Myocytes, Cardiac; Patch-Clamp Techniques; Peptide Fragments; Phenylephrine; Prazosin; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Receptors, Adrenergic, alpha-1; Tetradecanoylphorbol Acetate; Time Factors

2007
Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation of pore forming subunits.
    The Journal of physiology, 2007, Jun-01, Volume: 581, Issue:Pt 2

    Topics: Calcium; Cell Line; Diglycerides; Enzyme Activators; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Indoles; Ion Channel Gating; Ionomycin; Ionophores; Maleimides; Membrane Potentials; Methacholine Chloride; Muscarinic Agonists; Mutation; Phosphorylation; Potassium; Protein Kinase C; Protein Kinase Inhibitors; Receptor, Muscarinic M3; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection

2007
Regulation of matrix Gla protein by parathyroid hormone in MC3T3-E1 osteoblast-like cells involves protein kinase A and extracellular signal-regulated kinase pathways.
    Journal of cellular biochemistry, 2007, Oct-01, Volume: 102, Issue:2

    Topics: 3T3 Cells; Animals; Butadienes; Calcium-Binding Proteins; Colforsin; Cyclic AMP-Dependent Protein Kinases; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Indoles; Isoquinolines; Maleimides; Matrix Gla Protein; Mice; Nitriles; Osteoblasts; Parathyroid Hormone; Promoter Regions, Genetic; Protein Kinase C; Recombinant Proteins; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate

2007
Involvement of nPKC-MAPK pathway in the decrease of nucleophosmin/B23 during megakaryocytic differentiation of human myelogenous leukemia K562 cells.
    Life sciences, 2007, May-08, Volume: 80, Issue:22

    Topics: Carbazoles; Cell Differentiation; Cell Line, Tumor; Humans; Indoles; K562 Cells; Leukemia, Myeloid; Maleimides; Megakaryocytes; Mitogen-Activated Protein Kinases; Nuclear Proteins; Nucleolin; Nucleophosmin; Phosphoproteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase C; RNA-Binding Proteins; Tetradecanoylphorbol Acetate

2007
Regulation of plasminogen activators in human thyroid follicular cells and their relationship to differentiated function.
    Journal of cellular physiology, 2007, Volume: 212, Issue:3

    Topics: Adenylyl Cyclases; Aprotinin; Cell Differentiation; Cells, Cultured; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Activators; Epidermal Growth Factor; Fibroblast Growth Factors; Flavonoids; Humans; Indoles; Insulin; Iodine; Iodine Radioisotopes; Maleimides; Mesylates; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Plasminogen Inactivators; Protein Kinase C; Protein Kinase C beta; Protein Kinase Inhibitors; Pyrroles; RNA, Messenger; Serine Proteinase Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Thyroid Gland; Thyrotropin; Time Factors; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

2007
Cytotoxic action of phorbol esters on human pancreatic cancer cells.
    International journal of cancer, 2007, Oct-01, Volume: 121, Issue:7

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Maleimides; Membrane Proteins; Mice; Myristoylated Alanine-Rich C Kinase Substrate; Pancreatic Neoplasms; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Xenograft Model Antitumor Assays

2007
The role of protein kinase C isoenzymes in the regulation of calcineurin activity in human peripheral blood mononuclear cells.
    International journal of molecular medicine, 2007, Volume: 20, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Base Sequence; Calcimycin; Calcineurin; Calcineurin Inhibitors; Carbazoles; DNA Primers; Enzyme Activation; Humans; In Vitro Techniques; Indoles; Ionophores; Isoenzymes; Leukocytes, Mononuclear; Maleimides; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate

2007
Phosphorylation of claudin-4 by PKCepsilon regulates tight junction barrier function in ovarian cancer cells.
    Experimental cell research, 2007, Sep-10, Volume: 313, Issue:15

    Topics: Cell Line, Tumor; Claudin-4; Female; Humans; Indoles; Maleimides; Membrane Proteins; Mutation; Ovarian Neoplasms; Phosphorylation; Protein Isoforms; Protein Kinase C-epsilon; Signal Transduction; Tetradecanoylphorbol Acetate; Tight Junctions

2007
Activation of epidermal akt by diverse mouse skin tumor promoters.
    Molecular cancer research : MCR, 2007, Volume: 5, Issue:12

    Topics: Animals; Anthracenes; Anticoagulants; Carcinogens; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Epidermis; ErbB Receptors; Female; Heparin; Indoles; Keratinocytes; Maleimides; Mice; Mice, Inbred ICR; Okadaic Acid; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Tetradecanoylphorbol Acetate

2007
Opposite effect of phorbol ester PMA on PTGS2 and PGDH mRNA expression in human chorion trophoblast cells.
    Reproductive sciences (Thousand Oaks, Calif.), 2008, Volume: 15, Issue:1

    Topics: Calcium; Carcinogens; Cells, Cultured; Chorion; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Humans; Hydroxyprostaglandin Dehydrogenases; Imidazoles; Indoles; Maleimides; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase 4; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Pregnancy; Protein Kinase C; Pyridines; RNA, Messenger; Tetradecanoylphorbol Acetate; Trophoblasts

2008
Effects of phorbol ester on vesicle dynamics as revealed by total internal reflection fluorescence microscopy.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 457, Issue:1

    Topics: Animals; Cytoplasmic Vesicles; Diglycerides; Electrophysiology; Enzyme Inhibitors; Exocytosis; Green Fluorescent Proteins; Indoles; Maleimides; Microscopy, Fluorescence; Movement; Neuropeptide Y; PC12 Cells; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

2008
P70 S6 kinase negatively regulates fibroblast growth factor 2-stimulated interleukin-6 synthesis in osteoblasts: function at a point downstream from protein kinase C.
    The Journal of endocrinology, 2008, Volume: 197, Issue:1

    Topics: Animals; Carbazoles; Cells, Cultured; Fibroblast Growth Factor 2; Indoles; Interleukin-6; Maleimides; Mice; Osteoblasts; Phosphorylation; Protein Kinase C; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Tetradecanoylphorbol Acetate

2008
Modulation of cytokine production by plant sterols in stimulated human Jurkat T cells.
    Molecular nutrition & food research, 2008, Volume: 52, Issue:6

    Topics: Cell Division; Cell Survival; Cholesterol; Concanavalin A; Cytokines; Enzyme Inhibitors; Humans; Immunologic Factors; Immunosuppressive Agents; Indoles; Interleukin-2; Jurkat Cells; Lymphocyte Activation; Maleimides; Phytosterols; Protein Kinase C; Sitosterols; T-Lymphocytes; Tacrolimus; Tetradecanoylphorbol Acetate

2008
Protein kinase C-mediated protection of motoneurons from excitotoxicity.
    Neuroscience letters, 2008, Jul-11, Volume: 439, Issue:2

    Topics: Animals; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acids; Glutamic Acid; Indoles; Maleimides; Motor Neurons; Neuroprotective Agents; Protein Kinase C; Rats; Spinal Cord; Tetradecanoylphorbol Acetate

2008
The role of P38 MAPK and PKC in BLP induced TNF-alpha release, apoptosis, and NFkappaB activation in THP-1 monocyte cells.
    The Journal of surgical research, 2009, Volume: 151, Issue:1

    Topics: Apoptosis; Bacterial Proteins; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; Indoles; Inflammation; Lipopolysaccharides; Lipoproteins; Maleimides; Monocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2009
Electrogenic NBCe1 (SLC4A4), but not electroneutral NBCn1 (SLC4A7), cotransporter undergoes cholinergic-stimulated endocytosis in salivary ParC5 cells.
    American journal of physiology. Cell physiology, 2008, Volume: 295, Issue:5

    Topics: Animals; Bicarbonates; Biotinylation; Calmodulin; Carbachol; Cell Line; Cell Membrane; Cell Polarity; Cholinergic Agonists; Endocytosis; Endosomes; Gene Transfer Techniques; Hydrogen-Ion Concentration; Indoles; Maleimides; Microscopy, Confocal; Monensin; Parotid Gland; Protein Kinase C; Protein Kinase Inhibitors; Protein Transport; Rats; Receptors, Muscarinic; Sodium-Bicarbonate Symporters; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors; Xenopus laevis

2008
Exogenous nitric oxide-induced release of calcium from intracellular IP3 receptor-sensitive stores via S-nitrosylation in respiratory burst-dependent neutrophils.
    Biochemical and biophysical research communications, 2008, Dec-26, Volume: 377, Issue:4

    Topics: Calcium; Cells, Cultured; Humans; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Maleimides; Neutrophils; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Protein Kinase C; Protein Kinase Inhibitors; Respiratory Burst; Tetradecanoylphorbol Acetate

2008
Roles of protein kinase C isotypes during seawater-versus cAMP-induced oocyte maturation in a marine worm.
    Molecular reproduction and development, 2009, Volume: 76, Issue:8

    Topics: Animals; Bridged-Ring Compounds; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunoblotting; Indoles; Invertebrates; Isoenzymes; Maleimides; Neomycin; Norbornanes; Oocytes; Protein Kinase C; Seawater; Signal Transduction; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones

2009
Alteration of the PKC-mediated signaling pathway for smooth muscle contraction in obstruction-induced hypertrophy of the urinary bladder.
    Laboratory investigation; a journal of technical methods and pathology, 2009, Volume: 89, Issue:7

    Topics: Animals; Disease Models, Animal; Humans; Hypertrophy; In Vitro Techniques; Indoles; Male; Maleimides; Muscle Contraction; Muscle Proteins; Muscle, Smooth; Phosphoproteins; Phosphorylation; Potassium Chloride; Protein Kinase C; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Urinary Bladder; Urinary Bladder Neck Obstruction

2009
Modulation of ileal apical Na+-dependent bile acid transporter ASBT by protein kinase C.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:3

    Topics: Bile Acids and Salts; Caco-2 Cells; Calcium; Cell Membrane; Chelating Agents; Chromones; Egtazic Acid; Enzyme Activators; Humans; Ileum; Indoles; Intestinal Mucosa; Kinetics; Maleimides; Morpholines; Organic Anion Transporters, Sodium-Dependent; Peptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Symporters; Tetradecanoylphorbol Acetate; Transfection

2009
Phosphorylation of histone H3 by protein kinase C signaling plays a critical role in the regulation of the developmentally important TBX2 gene.
    The Journal of biological chemistry, 2009, Sep-25, Volume: 284, Issue:39

    Topics: Binding Sites; Blotting, Western; Cell Line; Chromatin Immunoprecipitation; Enzyme Inhibitors; Fibroblasts; Flavonoids; Gene Expression; Histones; Humans; Imidazoles; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Kinase C; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; Serine; Signal Transduction; Sp1 Transcription Factor; T-Box Domain Proteins; Tetradecanoylphorbol Acetate

2009
Differential fading of inhibitory and excitatory B2 bradykinin receptor responses in rat sympathetic neurons: a role for protein kinase C.
    Journal of neurochemistry, 2009, Volume: 110, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Animals, Newborn; Bradykinin; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indoles; Maleimides; Membrane Potentials; Neural Inhibition; Neurons; Norepinephrine; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Sodium Channel Blockers; Statistics, Nonparametric; Superior Cervical Ganglion; Tetradecanoylphorbol Acetate; Tetrodotoxin; Time Factors; Tritium

2009
Identification of Thr29 as a critical phosphorylation site that activates the human proton channel Hvcn1 in leukocytes.
    The Journal of biological chemistry, 2010, Feb-19, Volume: 285, Issue:8

    Topics: Amino Acid Substitution; Carcinogens; Cell Line; Enzyme Inhibitors; Humans; Indoles; Ion Channel Gating; Ion Channels; Leukocytes; Maleimides; Mutation, Missense; NADPH Oxidases; Phosphorylation; Protein Kinase C-delta; Respiratory Burst; Tetradecanoylphorbol Acetate; Threonine

2010
Roles of phospholipase D in phorbol myristate acetate-stimulated neutrophil respiratory burst.
    Journal of cellular and molecular medicine, 2011, Volume: 15, Issue:3

    Topics: 1-Butanol; Calcium; Cells, Cultured; Diglycerides; Enzyme Inhibitors; Estrenes; Humans; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphodiesterase Inhibitors; Phospholipase D; Protein Kinase C; Protein Transport; Pyrrolidinones; Respiratory Burst; Tetradecanoylphorbol Acetate

2011
Protein kinase C regulates neurite outgrowth in spinal cord neurons.
    Neuroscience bulletin, 2010, Volume: 26, Issue:2

    Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Enzyme Activators; Enzyme Inhibitors; Indoles; Maleimides; Neurites; Neurons; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spinal Cord; Tetradecanoylphorbol Acetate; Time Factors

2010
Serine phosphorylation of glutathione S-transferase P1 (GSTP1) by PKCα enhances GSTP1-dependent cisplatin metabolism and resistance in human glioma cells.
    Biochemical pharmacology, 2010, Nov-01, Volume: 80, Issue:9

    Topics: Antineoplastic Agents; bcl-2-Associated X Protein; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Glioma; Glutathione S-Transferase pi; Humans; Indoles; Maleimides; Phosphorylation; Protein Kinase C-alpha; Protein Transport; RNA, Small Interfering; Serine; Tetradecanoylphorbol Acetate

2010
Mechanism of hCG-induced spermiation in the toad Rhinella arenarum (Amphibia, Anura).
    General and comparative endocrinology, 2010, Dec-01, Volume: 169, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amiloride; Animals; Bufo arenarum; Chorionic Gonadotropin; Cyclic AMP-Dependent Protein Kinases; Indoles; Isoquinolines; Male; Maleimides; Ouabain; Protein Kinase C; Sertoli Cells; Sodium-Potassium-Exchanging ATPase; Spermatozoa; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate

2010
Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA methylation in human pancreatic cancer cells.
    Journal of cellular biochemistry, 2011, Volume: 112, Issue:7

    Topics: Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Claudins; DNA Methylation; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Indoles; Isoenzymes; Maleimides; Membrane Proteins; Pancreatic Ducts; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Tight Junctions; Up-Regulation

2011
Claudin-18 is an early-stage marker of pancreatic carcinogenesis.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2011, Volume: 59, Issue:10

    Topics: Adenocarcinoma, Mucinous; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Carcinoma, Papillary; Cell Transformation, Neoplastic; Claudins; Enzyme Inhibitors; Humans; Indoles; Maleimides; Membrane Proteins; Pancreas; Pancreatic Neoplasms; Pancreatitis, Chronic; Protein Kinase C; Retrospective Studies; Stomach Neoplasms; Tetradecanoylphorbol Acetate

2011
Physiological effect of protein kinase C on ENaC-mediated lung liquid regulation in the adult rat lung.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Amiloride; Animals; Benzophenanthridines; Biological Transport; Cells, Cultured; Electric Impedance; Enzyme Inhibitors; Epithelial Cells; Epithelial Sodium Channels; Indoles; Ionomycin; Isotonic Solutions; Lung; Male; Maleimides; Protein Kinase C; Rats; Rats, Wistar; Ringer's Solution; Signal Transduction; Sodium Channel Blockers; Terbutaline; Tetradecanoylphorbol Acetate

2012
TPA induces the expression of EC-SOD in human monocytic THP-1 cells: involvement of PKC, MEK/ERK and NOX-derived ROS.
    Free radical research, 2012, Volume: 46, Issue:5

    Topics: Butadienes; Cell Differentiation; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Indoles; Macrophages; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Monocytes; NADPH Oxidases; Nitriles; Protein Kinase C; Reactive Oxygen Species; Superoxide Dismutase; Tetradecanoylphorbol Acetate

2012
Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain.
    The European journal of neuroscience, 2012, Volume: 36, Issue:3

    Topics: Adenosine Triphosphate; Animals; Carbazoles; Colforsin; Cyclic AMP-Dependent Protein Kinases; Ganglia, Spinal; Indoles; Inflammation; Male; Maleimides; MAP Kinase Signaling System; Membrane Potentials; Neurons; Pain; Phosphorylation; Protein Kinase C; Protein Transport; Purinergic P2X Receptor Agonists; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Sprague-Dawley; Receptor, PAR-2; Receptors, Purinergic P2X3; Tetradecanoylphorbol Acetate

2012
The Src kinase Yes is activated in pancreatic acinar cells by gastrointestinal hormones/neurotransmitters, but not pancreatic growth factors, which stimulate its association with numerous other signaling molecules.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:8

    Topics: Acinar Cells; Animals; Bombesin; Calcimycin; Calcium Ionophores; Calcium Signaling; Carbachol; Cholecystokinin; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Gastrointestinal Hormones; Indoles; Intercellular Signaling Peptides and Proteins; Male; Maleimides; Neurotransmitter Agents; Pancreas; Peptide Fragments; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-yes; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Thapsigargin

2012
6-Hydroxydopamine upregulates iron regulatory protein 1 by activating certain protein kinase C isoforms in the dopaminergic MES23.5 cell line.
    The international journal of biochemistry & cell biology, 2012, Volume: 44, Issue:11

    Topics: Cation Transport Proteins; Cell Line; Dopaminergic Neurons; Enzyme Activation; Indoles; Iron; Iron Regulatory Protein 1; Isoenzymes; Maleimides; Oxidopamine; Protein Kinase C; Tetradecanoylphorbol Acetate; Up-Regulation

2012
Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells.
    Archives of toxicology, 2013, Volume: 87, Issue:5

    Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Carcinogens; Cell Movement; Cell Survival; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Drug Antagonism; Enzyme Activation; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Gene Silencing; Heme Oxygenase-1; Humans; Indoles; Maleimides; Matrix Metalloproteinase 9; MCF-7 Cells; Neoplasm Invasiveness; Tetradecanoylphorbol Acetate; Time Factors; Wortmannin

2013
Protein kinase C regulates human pluripotent stem cell self-renewal.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Activins; Alkaline Phosphatase; Blotting, Western; Carbazoles; Cell Line; Cell Proliferation; Chromones; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunohistochemistry; Indoles; Maleimides; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Pluripotent Stem Cells; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Proto-Oncogene Proteins c-akt; RNA Interference; Signal Transduction; Tetradecanoylphorbol Acetate

2013
Protein kinase C activation inhibits rat and human hyperpolarization activated cyclic nucleotide gated channel (HCN)1--mediated current in mammalian cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2013, Volume: 31, Issue:4-5

    Topics: Animals; Cell Line; HEK293 Cells; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Indoles; Maleimides; Membrane Potentials; Mice; Patch-Clamp Techniques; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate

2013
Naproxen-induced Ca2+ movement and death in MDCK canine renal tubular cells.
    Human & experimental toxicology, 2015, Volume: 34, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Calcium Channel Blockers; Cell Death; Dogs; Imidazoles; Indoles; Madin Darby Canine Kidney Cells; Maleimides; Naproxen; Nifedipine; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate

2015
Activation of TRPM2 and TRPV1 Channels in Dorsal Root Ganglion by NADPH Oxidase and Protein Kinase C Molecular Pathways: a Patch Clamp Study.
    Journal of molecular neuroscience : MN, 2017, Volume: 61, Issue:3

    Topics: Acetophenones; Action Potentials; Animals; Calcium Signaling; Capsaicin; Cells, Cultured; Cinnamates; Ganglia, Spinal; Indoles; Male; Maleimides; NADPH Oxidases; Neurons; ortho-Aminobenzoates; Oxidative Stress; Protein Kinase C; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; TRPM Cation Channels; TRPV Cation Channels

2017
A novel DLX3-PKC integrated signaling network drives keratinocyte differentiation.
    Cell death and differentiation, 2017, Volume: 24, Issue:4

    Topics: Animals; Antimicrobial Cationic Peptides; Calcium; Cell Adhesion; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chemokines; Cytokines; Epidermis; Homeodomain Proteins; Humans; Hyperplasia; Indoles; Keratinocytes; Leukocytes; Maleimides; Mice; Mice, Transgenic; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factors

2017
α-Cyperone Inhibits PMA-Induced EPCR Shedding through PKC Pathway.
    Biological & pharmaceutical bulletin, 2017, Oct-01, Volume: 40, Issue:10

    Topics: ADAM17 Protein; Cell Survival; Endothelial Protein C Receptor; Human Umbilical Vein Endothelial Cells; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate

2017