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tetradecanoylphorbol acetate and beta-escin

tetradecanoylphorbol acetate has been researched along with beta-escin in 67 studies

Research

Studies (67)

TimeframeStudies, this research(%)All Research%
pre-19907 (10.45)18.7374
1990's32 (47.76)18.2507
2000's20 (29.85)29.6817
2010's7 (10.45)24.3611
2020's1 (1.49)2.80

Authors

AuthorsStudies
Itoh, T; Kuriyama, H; Suzuki, S1
Akao, M; Bremerich, DH; Hirasaki, A; Jones, KA; Warner, DO; Wong, GY1
Iwashima, A; Kokumai, M; Konoshima, T; Kozuka, M; Nishino, H; Tokuda, H1
Berthon, B; Claret, M; Combettes, L1
Chang, M; Fan, SX; He, WZ; Liu, WS; Ma, RD; Nishino, H; Takayasu, J; Wang, YQ; Yu, LJ; Zhen, J1
Kimura, T; Konoshima, T; Kozuka, M; Tokuda, H2
Bultmann, H; Glade, U; Häfker, T; Vicker, MG1
Akiba, S; Fujii, T; Sato, T2
Eckhardt, L; Imamura, K; Kimura, T; Schulz, I1
Nachmias, VT; Yoshida, K1
Becker, AB; Brandes, LJ; Gerrard, JM; McNicol, A; Saxena, SP1
Nachmias, VT; Stark, F; Yoshida, K1
Brass, LF; Laposata, M1
Inoue, T; Mimaki, Y; Nishino, A; Nishino, H; Sashida, Y; Satomi, Y1
Kuroda, M; Mimaki, Y; Nishino, A; Nishino, H; Sashida, Y; Satomi, Y1
Kanmoto, T; Kuroda, M; Mimaki, Y; Nishino, A; Nishino, H; Sashida, Y; Satomi, Y2
Koike, K; Mimaki, Y; Nakamura, O; Nikaido, T; Nishino, A; Nishino, H; Ohmoto, T; Sashida, Y; Satomi, Y1
Morgan, JP; Paik, GY; Perreault, CL; Wang, J1
Huang, C; Liang, NC1
Binder, BR; Wojta, J; Zhang, W1
Polgar, P; Ricupero, D; Taylor, L1
Kwan-Yeung, L; Wong, K1
Ma, R; Yu, L; Yu, T1
Fujikawa-Yamamoto, K; Odashima, S; Tanino, M; Teraoka, K; Yamagishi, H; Zong, Z1
Aitken, A; Learmonth, MP; Martin, H; Wheeler-Jones, CP1
Kanmoto, T; Mimaki, Y; Nishino, A; Nishino, H; Sashida, Y; Satomi, Y1
Crain, RC; Hoagland, TA; Mirando, MA; Tysseling, KA; Uzumcu, M1
Bilia, AR; Cuéllar, MJ; Giner, RM; Hostettmann, K; Just, MJ; Máñez, S; Msonthi, J; Recio, MC; Ríos, JL1
Cerdá, M; Cuéllar, MJ; Giner, RM; Hostettmann, K; Just, MJ; Máñez, S; Recio, MC; Ríos, JL1
Hamilton, BP; Hamlyn, JM; Laredo, J; Shah, JR1
Bei, L; Hu, T; Qian, ZM; Shen, X1
Duc, NM; Kasai, R; Konoshima, T; Nishino, H; Takasaki, M; Tokuda, H; Yamasaki, K1
Abad Martínez, MJ; Bermejo Benito, P; Díaz Lanza, AM; Fernández Matellano, L; Sánchez Contreras, S; Sanz Gómez, A; Silván Sen, AM1
Kodama, H; Meng, Z; Sagara, Y; Sugahara, K; Xu, S; Zhang, J; Zhang, M1
Duc, NM; Ichiishi, E; Kasai, R; Konoshima, T; Murakami, T; Nishino, H; Takasaki, M; Tokuda, H; Yamasaki, K1
Cerdá-Nicolás, M; Giner, RM; Máñez, S; Recio, MC; Ríos, J; Villalba, ML1
Lee, DK; Park, S; Whang, YH; Yang, CH1
Che, JH; Kang, BC; Kang, KS; Lee, BJ; Lee, YS; Li, GX; Trosko, JE1
Doi, Y; Kaname, N; Kodama, H; Meng, Z; Sugahara, K; Xu, S; Zhang, J1
Eisenreichová, E; Haladová, M; Józová, B; Mucaji, P; Novotný, L; Vachálková, A1
Cerdá-Nicolás, M; Giner, RM; Máñez, S; Navarro, P; Recio, MC; Ríos, JL1
Gong, YS; Zhang, JT1
Hsu, HY; Wu, WS1
Ban, HS; Kim, SY; Kim, YP; Lee, EB; Li, D; Lim, SS; Ohuchi, K; Shin, KH1
Arntzen, CJ; Ganesh, P; Gutterman, JU; Hanausek, M; Slaga, TJ; Walaszek, Z1
Ma, RD; Yu, LJ; Yu, TX1
Hashimoto, N; Morita, T; Nezu, A; Tanimura, A; Tojyo, Y1
Wen-Sheng, W1
Chen, G; Kitaoka, N; Kodama, H; Lu, H; Manabe, M; Sagara, Y; Song, S; Wang, Z; Xu, S1
Kim, HY; Kim, JS; Kim, YK; Sung, MK; Yu, R1
Duke, CC; Duke, RK; Huang, TH; Razmovski-Naumovski, V; Roufogalis, BD; Salam, NK; Tran, VH1
Lotze, MT; Montag, DT1
Huang, HC; Kuo, YH; Lee, KH; Morris-Natschke, SL; Tokuda, H; Tsai, WJ; Wu, YC1
Görick, C; Jenett-Siems, K; Melzig, MF; Weng, A1
Bachran, C; Fuchs, H; Melzig, MF; Weng, A1
Chung, WY; Hwang, YS; Park, HJ; Park, KK; Park, SK; Seo, JY1
Chung, WY; Hwang, YS; Park, KK1
Jeong, JJ; Joh, EH; Kim, DH1
Gonzalez-Cortazar, M; Herrera-Ruiz, M; Jiménez-Aparicio, AR; Jiménez-Ferrer, E; Monterrosas-Brisson, N; Ocampo, ML; Tortoriello, J; Zamilpa, A1
Chen, XP; Li, T; Lu, JJ; Wang, YT; Wu, GS; Xu, WS1
Choi, CY; Choi, JH; Chung, YC; Hwang, YJ; Jeong, HG; Jeong, TC; Jin, SW; Kim, HG; Lee, HS; Ryu, SY; Um, YJ1
Hong, JH; Kim, YS; Lee, CJ; Lee, HJ; Lee, SK; Park, JS; Shin, YJ; Son, KH; Yoon, YP1
Geng, Y; He, C; Li, L; Li, Y; Liang, X; Ma, Y; Shu, G; Song, X; Ye, G; Yin, L; Yin, Z; Yue, G; Zhang, R; Zhao, Y; Zou, Y1
Aragón, M; Castellanos, L; Costa, GM; Ospina, LF; Ramos, FA; Sepúlveda, P; Urrego, N1

Reviews

1 review(s) available for tetradecanoylphorbol acetate and beta-escin

ArticleYear
Calcium sequestration in human platelets: is it stimulated by protein kinase C?
    Cell calcium, 1989, Volume: 10, Issue:5

    Topics: Benzofurans; Blood Platelets; Calcium; Enzyme Activation; Fluorescent Dyes; Fura-2; Humans; Kinetics; Phosphorylation; Prostaglandins E; Protein Kinase C; Saponins; Tetradecanoylphorbol Acetate; Thrombin

1989

Other Studies

66 other study(ies) available for tetradecanoylphorbol acetate and beta-escin

ArticleYear
Effects of pinacidil on contractile proteins in high K(+)-treated intact, and in beta-escin-treated skinned smooth muscle of the rabbit mesenteric artery.
    British journal of pharmacology, 1991, Volume: 103, Issue:3

    Topics: Animals; Calcium; Contractile Proteins; Escin; Fura-2; Guanidines; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Myelin Sheath; Pinacidil; Potassium; Rabbits; Tetradecanoylphorbol Acetate; Vasodilator Agents

1991
Halothane reduces myofilament Ca2+ sensitivity during muscarinic receptor stimulation of airway smooth muscle.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 1

    Topics: Acetylcholine; Animals; Calcium; Cell Membrane Permeability; Cytosol; Dogs; Escin; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Halothane; In Vitro Techniques; Isometric Contraction; Male; Muscle, Smooth; Protein Kinase C; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Trachea

1996
Anti-tumor-promoting activities of afromosin and soyasaponin I isolated from Wistaria brachybotrys.
    Journal of natural products, 1992, Volume: 55, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cocarcinogenesis; Female; Isoflavones; Lung Neoplasms; Mice; Mice, Inbred ICR; Oleanolic Acid; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate

1992
Taurolithocholate-induced Ca2+ release is inhibited by phorbol esters in isolated hepatocytes.
    The Biochemical journal, 1992, Nov-01, Volume: 287 ( Pt 3)

    Topics: Animals; Calcium; Diglycerides; Enzyme Activation; Female; Liver; Protein Kinase C; Rats; Rats, Wistar; Saponins; Taurolithocholic Acid; Tetradecanoylphorbol Acetate; Vasopressins

1992
Potent anti-tumorigenic effect of tubeimoside 1 isolated from the bulb of Bolbostemma paniculatum (Maxim) Franquet.
    International journal of cancer, 1992, Feb-20, Volume: 50, Issue:4

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Body Weight; Female; Mice; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes

1992
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin papilloma by saponins.
    Oncology, 1991, Volume: 48, Issue:1

    Topics: Animals; Female; Herpesvirus 4, Human; Mice; Mice, Inbred ICR; Papilloma; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Virus Activation

1991
Ionizing radiation at low doses induces inflammatory reactions in human blood.
    Radiation research, 1991, Volume: 128, Issue:3

    Topics: Arachidonic Acid; Blood; Blood Cells; Calcimycin; Dose-Response Relationship, Radiation; Escherichia coli; Gamma Rays; Humans; Inflammation; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Radiation Dosage; Respiratory Burst; Saponins; Tetradecanoylphorbol Acetate

1991
Involvement of a guanine-nucleotide-binding protein-mediated mechanism in the enhancement of arachidonic acid liberation by phorbol 12-myristate 13-acetate and Ca2+ in saponin-permeabilized platelets.
    Biochimica et biophysica acta, 1990, Jun-14, Volume: 1044, Issue:3

    Topics: Alkaloids; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cell Membrane Permeability; Chlorides; Diglycerides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Pertussis Toxin; Protein Kinase C; Rabbits; Saponins; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella

1990
Ca2+-, phorbol ester-, and cAMP-stimulated enzyme secretion from permeabilized rat pancreatic acini.
    The American journal of physiology, 1986, Volume: 250, Issue:5 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Amylases; Animals; Calcium; Carbachol; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cytoplasmic Granules; Digitonin; Egtazic Acid; Pancreas; Phorbols; Rats; Rats, Inbred Strains; Saponins; Spermine; Tetradecanoylphorbol Acetate; Trifluoperazine

1986
Differential effects of phorbol 12-myristate 13-acetate on GTP gamma S-induced diacylglycerol formation and arachidonic acid liberation in saponin-permeabilized rabbit platelets.
    Thrombosis research, 1989, Mar-01, Volume: 53, Issue:5

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Diglycerides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Lipids; Permeability; Phospholipases A; Phospholipases A2; Rabbits; Saponins; Tetradecanoylphorbol Acetate; Thionucleotides; Type C Phospholipases

1989
Histamine formed in stimulated human platelets is cytoplasmic.
    Biochemical and biophysical research communications, 1989, Oct-16, Volume: 164, Issue:1

    Topics: Blood Platelets; Cytoplasm; Female; Histamine; Humans; Male; Phosphatidylethanolamines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Saponins; Serotonin; Tetradecanoylphorbol Acetate; Thrombin

1989
Comparison of the effects of phorbol 12-myristate 13-acetate and prostaglandin E1 on calcium regulation in human platelets.
    The Biochemical journal, 1988, Jan-15, Volume: 249, Issue:2

    Topics: Alprostadil; Biological Transport; Blood Platelets; Blood Proteins; Calcium; Cyclic AMP; Humans; In Vitro Techniques; Microsomes; Phosphorylation; Protein Kinase C; Saponins; Tetradecanoylphorbol Acetate; Thrombin

1988
Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate and teleocidin B induced Epstein-Barr virus by saponin and its related compounds.
    Cancer letters, 1988, Jun-30, Volume: 40, Issue:3

    Topics: Antineoplastic Agents; Cell Line; Herpesvirus 4, Human; Humans; Lyngbya Toxins; Sapogenins; Saponins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Virus Activation

1988
Diacylglycerol causes Ca release from the platelet dense tubular system: comparisons with Ca release caused by inositol 1,4,5-triphosphate.
    Biochemical and biophysical research communications, 1987, Jan-15, Volume: 142, Issue:1

    Topics: Adenosine Triphosphate; Aspirin; Blood Platelets; Calcium; Diglycerides; Dose-Response Relationship, Drug; Glycerides; Humans; Indomethacin; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Membranes; Lysophospholipids; Phosphatidic Acids; Platelet Aggregation; Saponins; Serotonin; Sugar Phosphates; Tetradecanoylphorbol Acetate

1987
Steroidal glycosides from Allium macleanii and A. senescens, and their inhibitory activity on tumour promoter-induced phospholipid metabolism of HeLa cells.
    Phytochemistry, 1995, Volume: 40, Issue:2

    Topics: Allium; Anticarcinogenic Agents; Carbohydrate Conformation; Carbohydrate Sequence; Carcinogens; HeLa Cells; Humans; Molecular Sequence Data; Oligosaccharides; Phospholipids; Saponins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1995
Inhibitory effects of steroidal saponins on 12-O-tetradecanoylphorbol-13-acetate (TPA)-enhanced 32P-incorporation into phospholipids of HeLa cells and proliferation of human malignant tumor cells.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:3

    Topics: Carbohydrate Sequence; Cell Division; Drug Interactions; HeLa Cells; Humans; Molecular Sequence Data; Neoplasms; Phospholipids; Phosphorus; Phosphorus Radioisotopes; Saponins; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1995
Steroidal saponins from the underground parts of Hosta longipes and their inhibitory activity on tumor promoter-induced phospholipid metabolism.
    Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:7

    Topics: Anticarcinogenic Agents; Carbohydrate Conformation; Carbohydrate Sequence; Carbon Isotopes; HeLa Cells; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phospholipids; Plant Extracts; Plants; Protons; Saponins; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1995
Structures of steroidal saponins from the tubers of Brodiaea californica and their inhibitory activity on tumor promoter-induced phospholipid metabolism.
    Chemical & pharmaceutical bulletin, 1995, Volume: 43, Issue:6

    Topics: Anticarcinogenic Agents; Carbohydrate Sequence; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Sequence Data; Phospholipids; Plant Roots; Plants, Medicinal; Saponins; Tetradecanoylphorbol Acetate

1995
Endothelin-1 does not alter Ca2+ responsiveness in saponin-skinned ferret papillary muscles.
    European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3

    Topics: Animals; Calcium; Computer Simulation; Diglycerides; Electrophysiology; Endothelins; Ferrets; Heart Ventricles; Male; Myocardial Contraction; Papillary Muscles; Phosphatidylinositols; Saponins; Tetradecanoylphorbol Acetate

1994
Increase in cytoskeletal actin induced by inositol 1,4-bisphosphate in saponin-permeated pig platelets.
    Cell biology international, 1994, Volume: 18, Issue:8

    Topics: Actins; Animals; Blood Platelets; Cell Membrane Permeability; Cladribine; Cytoskeleton; Dose-Response Relationship, Drug; Inositol Phosphates; Platelet Activation; Polymers; Saponins; Second Messenger Systems; Spermine; Swine; Tetradecanoylphorbol Acetate; Thrombin

1994
Effect of notoginsenoside R1 on the synthesis of tissue-type plasminogen activator and plasminogen activator inhibitor-1 in cultured human umbilical vein endothelial cells.
    Arteriosclerosis and thrombosis : a journal of vascular biology, 1994, Volume: 14, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Blotting, Northern; Cells, Cultured; DNA Probes; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Gene Expression; Ginsenosides; Humans; Plasminogen Activator Inhibitor 1; RNA, Messenger; Saponins; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Tretinoin; Umbilical Veins; Urokinase-Type Plasminogen Activator

1994
Interactions of bradykinin, calcium, G-protein and protein kinase in the activation of phospholipase A2 in bovine pulmonary artery endothelial cells.
    Agents and actions, 1993, Volume: 40, Issue:1-2

    Topics: Animals; Arachidonic Acid; Bradykinin; Calcium; Cattle; Cytosol; Endothelium, Vascular; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ion-Selective Electrodes; Pertussis Toxin; Phospholipases A; Phospholipases A2; Protein Kinase C; Protein Kinases; Pulmonary Artery; Saponins; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1993
Sphingosine mobilizes intracellular calcium in human neutrophils.
    Cell calcium, 1993, Volume: 14, Issue:6

    Topics: Biological Transport; Calcium; Cell Compartmentation; Cell Death; Dose-Response Relationship, Drug; Edetic Acid; Fluorescent Dyes; Fura-2; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ionomycin; Manganese; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphorylcholine; Saponins; Sphingosine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella

1993
Inhibition of the tumor promoting action of 12-O-tetradecanoylphorbol-13-acetate by tubeimoside III isolated from Bolbostemma paniculatum.
    Carcinogenesis, 1995, Volume: 16, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Carbohydrate Sequence; Cell Line; Drugs, Chinese Herbal; Male; Mice; Mice, Inbred C3H; Molecular Sequence Data; Phospholipids; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes; Tritium

1995
Saikosaponin b2-induced apoptosis of cultured B16 melanoma cell line through down-regulation of PKC activity.
    Biochemical and biophysical research communications, 1996, Feb-15, Volume: 219, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line; Cell Nucleus; DNA, Neoplasm; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Kinetics; Melanoma, Experimental; Mice; Oleanolic Acid; Protein Kinase C; Sapogenins; Saponins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1996
Identification of 14-3-3 proteins in human platelets: effects of synthetic peptides on protein kinase C activation.
    The Biochemical journal, 1996, Apr-01, Volume: 315 ( Pt 1)

    Topics: 14-3-3 Proteins; Amino Acid Sequence; Animals; Blood Platelets; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Enzyme Activation; Humans; Isomerism; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Kinase C; Proteins; Saponins; Sheep; Tetradecanoylphorbol Acetate; Tyrosine 3-Monooxygenase

1996
Steroidal saponins from Hosta longipes and their inhibitory activity on tumour promoter-induced phospholipid metabolism of HeLa cells.
    Phytochemistry, 1996, Volume: 42, Issue:4

    Topics: Carbohydrate Conformation; Carbohydrate Sequence; Carcinogens; HeLa Cells; Humans; Molecular Sequence Data; Molecular Structure; Phospholipids; Plant Roots; Plants; Saponins; Spectrometry, Mass, Fast Atom Bombardment; Steroids; Tetradecanoylphorbol Acetate

1996
Steroidal saponins from the underground parts of Chlorophytum comosum and their inhibitory activity on tumour promoter-induced phospholipids metabolism of HeLa cells.
    Phytochemistry, 1996, Volume: 41, Issue:5

    Topics: Anticarcinogenic Agents; Carbohydrate Conformation; Carbohydrate Sequence; HeLa Cells; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phospholipids; Plant Extracts; Plant Roots; Saponins; Steroids; Tetradecanoylphorbol Acetate

1996
The role of phosphoinositide-derived second messengers in oxytocin-stimulated prostaglandin F2 alpha release from endometrium of pigs.
    Domestic animal endocrinology, 1996, Volume: 13, Issue:5

    Topics: Analysis of Variance; Animals; Diglycerides; Dinoprost; Endometrium; Estrus; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Kinetics; L-Lactate Dehydrogenase; Oxytocin; Phosphatidylinositols; Saponins; Second Messenger Systems; Swine; Tetradecanoylphorbol Acetate

1996
Three new oleanane saponins from Zanha africana.
    Journal of natural products, 1997, Volume: 60, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Ear; Edema; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Plants, Medicinal; Saponins; Tetradecanoylphorbol Acetate; Trees

1997
Zanhasaponins A and B, antiphospholipase A2 saponins from an antiinflammatory extract of Zanha africana root bark.
    Journal of natural products, 1997, Volume: 60, Issue:11

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Dermatitis, Contact; Edema; Enzyme Inhibitors; Female; Mice; Oxazolone; Peroxidase; Phospholipases A; Phospholipases A2; Saponins; Skin; Tetradecanoylphorbol Acetate; Triterpenes

1997
Different signaling pathways mediate stimulated secretions of endogenous ouabain and aldosterone from bovine adrenocortical cells.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Factors; Bucladesine; Cardenolides; Cattle; Cells, Cultured; Digoxin; Enzyme Inhibitors; Imidazoles; Ouabain; Pyridines; Receptor, Angiotensin, Type 2; Saponins; Signal Transduction; Tetradecanoylphorbol Acetate; Zona Glomerulosa

1998
Extracellular Ca2+ regulates the respiratory burst of human neutrophils.
    Biochimica et biophysica acta, 1998, Sep-16, Volume: 1404, Issue:3

    Topics: Calcium; Cytosol; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Respiratory Burst; Saponins; Tetradecanoylphorbol Acetate; Thapsigargin

1998
Anti-tumor-promoting activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. (I).
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antigens, Viral; Carboxylic Acids; Fumonisins; Ginsenosides; Male; Mice; Mice, Inbred ICR; Papilloma; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate

1998
In vivo and in vitro antiinflammatory activity of saikosaponins.
    Life sciences, 1998, Volume: 63, Issue:13

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Carbohydrate Sequence; Cell Survival; Cells, Cultured; Dinoprostone; Ear, External; Edema; Female; Humans; Leukotriene C4; Macrophages, Peritoneal; Male; Mice; Molecular Sequence Data; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Sapogenins; Saponins; Tetradecanoylphorbol Acetate

1998
Effect of steroidal saponins of Anemarrhenae rhizoma on superoxide generation in human neutrophils.
    Biochemical and biophysical research communications, 1999, Jun-16, Volume: 259, Issue:3

    Topics: Arachidonic Acid; Dose-Response Relationship, Drug; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Prednisolone; Saponins; Superoxides; Tetradecanoylphorbol Acetate

1999
Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis.
    Cancer letters, 1999, Dec-01, Volume: 147, Issue:1-2

    Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Diethylnitrosamine; Female; Focal Nodular Hyperplasia; Ginsenosides; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Mice, Inbred SENCAR; Nitrates; Nitro Compounds; Panax; Papilloma; Phenobarbital; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vietnam

1999
Anti-inflammatory glycoterpenoids from Scrophularia auriculata.
    European journal of pharmacology, 2000, Feb-18, Volume: 389, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents; Capillary Permeability; Ear; Edema; Female; Glucosides; Glycosides; Hypersensitivity, Delayed; Iridoid Glycosides; Iridoids; Mice; Plants, Medicinal; Pyrans; Saponins; Serotonin; Terpenes; Tetradecanoylphorbol Acetate; Triterpenes

2000
Momordin I, a compound of ampelopsis radix, inhibits AP-1 activation induced by phorbol ester.
    Cancer letters, 2000, Apr-28, Volume: 152, Issue:1

    Topics: 3T3 Cells; Animals; Binding, Competitive; Cell Division; Cell Survival; Mice; Oleanolic Acid; Plants; Proto-Oncogene Proteins c-jun; RNA, Messenger; Saponins; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2000
Preventive effect of epicatechin and ginsenoside Rb(2) on the inhibition of gap junctional intercellular communication by TPA and H(2)O(2).
    Cancer letters, 2000, Apr-28, Volume: 152, Issue:1

    Topics: Animals; Catechin; Cell Communication; Cells, Cultured; Connexin 43; Epithelial Cells; Gap Junctions; Ginsenosides; Hydrogen Peroxide; Liver; Phosphorylation; Rats; Saponins; Tetradecanoylphorbol Acetate

2000
Effect of timosaponin E1 and E2 on superoxide generation induced by various stimuli in human neutrophils and on platelet aggregation in human blood.
    Clinica chimica acta; international journal of clinical chemistry, 2000, Volume: 295, Issue:1-2

    Topics: Blood Proteins; Carbohydrate Sequence; Hemolysis; Humans; Neutrophils; Phosphorylation; Platelet Aggregation Inhibitors; Saponins; Steroids; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine

2000
Potential carcinogenic and inhibitory activity of compounds isolated from Lilium candidum L.
    Neoplasma, 2000, Volume: 47, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Ethanol; Liliaceae; Mice; Mutagens; Plant Extracts; Polarography; Pyrroles; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate

2000
In vivo anti-inflammatory activity of saponins from Bupleurum rotundifolium.
    Life sciences, 2001, Jan-26, Volume: 68, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Female; Mice; Plants, Medicinal; Saponins; Tetradecanoylphorbol Acetate

2001
Effect of 17-beta-estradiol and ginsenoside Rg1 on reactive microglia induced by beta-amyloid peptides.
    Journal of Asian natural products research, 1999, Volume: 1, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Cell Survival; Central Nervous System Agents; Cerebral Cortex; Drug Interactions; Drugs, Chinese Herbal; Estradiol; Ginsenosides; Interferon-gamma; Microglia; Nitrites; Nootropic Agents; Peptide Fragments; Rats; Respiratory Burst; Saponins; Tetradecanoylphorbol Acetate

1999
Involvement of p-15(INK4b) and p-16(INK4a) gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells.
    Biochemical and biophysical research communications, 2001, Jul-13, Volume: 285, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Carrier Proteins; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Liver Neoplasms; Oleanolic Acid; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sapogenins; Saponins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins

2001
Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.
    Planta medica, 2001, Volume: 67, Issue:4

    Topics: Animals; Arachidonic Acid; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dexamethasone; Dinoprostone; Drugs, Chinese Herbal; Enzyme Induction; Indomethacin; Isoenzymes; Macrophages, Peritoneal; Membrane Proteins; Oleanolic Acid; Plant Roots; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Rats; Rats, Sprague-Dawley; Saponins; Tetradecanoylphorbol Acetate; Triterpenes

2001
Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), suppress H-ras mutations and aneuploidy in a murine skin carcinogenesis model.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Sep-25, Volume: 98, Issue:20

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acacia; Aneuploidy; Animals; Dioxoles; Disease Models, Animal; Female; Genes, ras; Humans; Jurkat Cells; Mice; Mice, Inbred SENCAR; Papilloma; Phenanthridines; Phytotherapy; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes

2001
Structure-activity relationship of tubeimosides in anti-inflammatory, antitumor, and antitumor-promoting effects.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Cucurbitaceae; Disease Models, Animal; Edema; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Molecular Structure; Neoplasms, Experimental; Saponins; Sarcoma 180; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Treatment Outcome; Triterpenes

2001
Interplay between calcium, diacylglycerol, and phosphorylation in the spatial and temporal regulation of PKCalpha-GFP.
    The Journal of biological chemistry, 2002, Aug-09, Volume: 277, Issue:32

    Topics: Adenosine Triphosphate; Calcium; Carcinogens; Cell Line; Cell Membrane; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Green Fluorescent Proteins; Humans; Ionomycin; Ionophores; Isoenzymes; Luminescent Proteins; Magnesium; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-alpha; Recombinant Fusion Proteins; Saponins; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Transfection

2002
ERK signaling pathway is involved in p15INK4b/p16INK4a expression and HepG2 growth inhibition triggered by TPA and Saikosaponin a.
    Oncogene, 2003, Feb-20, Volume: 22, Issue:7

    Topics: Activating Transcription Factor 2; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Division; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Depression, Chemical; Electrophoresis, Capillary; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Genes, p16; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Oleanolic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Saponins; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins

2003
Effect of three triterpenoid compounds isolated from root bark of Aralia elata on stimulus-induced superoxide generation and tyrosyl phosphorylation and translocation of p47(phox) and p67(phox) to cell membrane in human neutrophil.
    Clinica chimica acta; international journal of clinical chemistry, 2003, Volume: 336, Issue:1-2

    Topics: Arachidonic Acid; Aralia; Cell Membrane; Humans; Immunoblotting; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Plant Bark; Plant Roots; Protein Transport; Saponins; Superoxides; Tetradecanoylphorbol Acetate; Triterpenes; Tyrosine

2003
Antiproliferative crude soy saponin extract modulates the expression of IkappaBalpha, protein kinase C, and cyclooxygenase-2 in human colon cancer cells.
    Cancer letters, 2004, Jul-08, Volume: 210, Issue:1

    Topics: Blotting, Western; Cell Division; Colonic Neoplasms; Cyclooxygenase 2; Gene Expression Regulation; Glycine max; Humans; I-kappa B Proteins; Isoenzymes; Membrane Proteins; NF-KappaB Inhibitor alpha; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Saponins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2004
A novel LXR-alpha activator identified from the natural product Gynostemma pentaphyllum.
    Biochemical pharmacology, 2005, Nov-01, Volume: 70, Issue:9

    Topics: Apolipoproteins E; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cell Line; DNA-Binding Proteins; Gynostemma; Humans; Ligands; Liver X Receptors; Models, Molecular; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Saponins; Tetradecanoylphorbol Acetate

2005
Successful simultaneous measurement of cell membrane and cytokine induced phosphorylation pathways [CIPP] in human peripheral blood mononuclear cells.
    Journal of immunological methods, 2006, Jun-30, Volume: 313, Issue:1-2

    Topics: Acetone; Antigens, CD; Antigens, Surface; Cell Membrane Permeability; Cytokines; Flow Cytometry; Humans; Interferon-alpha; Interferon-gamma; Interleukin-10; Interleukin-2; Interleukin-4; Leukocytes, Mononuclear; Methanol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Saponins; STAT Transcription Factors; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate

2006
Sapinmusaponins F-J, bioactive tirucallane-type saponins from the galls of Sapindus mukorossi.
    Journal of natural products, 2006, Volume: 69, Issue:5

    Topics: Animals; Antigens, Viral; Blood Platelets; L-Lactate Dehydrogenase; Molecular Structure; Plant Tumors; Rabbits; Sapindaceae; Saponins; Taiwan; Tetradecanoylphorbol Acetate

2006
Enhancement of cytotoxicity of ribosome-inactivating-protein type I by saponinum album is not based on stimulation of phagocytosis.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:7

    Topics: Caryophyllaceae; Cell Survival; Drug Synergism; Humans; Immunologic Factors; Interferon-gamma; Phagocytosis; Ribosome Inactivating Proteins, Type 1; Saponins; Tetradecanoylphorbol Acetate; Triterpenes; U937 Cells

2008
Enhancement of saporin toxicity against U937 cells by Gypsophila saponins.
    Journal of immunotoxicology, 2008, Volume: 5, Issue:3

    Topics: Apoptosis; Caryophyllaceae; Endocytosis; Humans; Immunotoxins; Inhibitory Concentration 50; Macrophages; Ribosome Inactivating Proteins, Type 1; Saponins; Saporins; Tetradecanoylphorbol Acetate; U937 Cells

2008
Kalopanaxsaponin A inhibits PMA-induced invasion by reducing matrix metalloproteinase-9 via PI3K/Akt- and PKCdelta-mediated signaling in MCF-7 human breast cancer cells.
    Carcinogenesis, 2009, Volume: 30, Issue:7

    Topics: Acetophenones; Animals; Antineoplastic Agents, Phytogenic; Benzopyrans; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; Neoplasm Transplantation; NF-kappa B; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C-delta; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transplantation, Heterologous

2009
Kalopanaxsaponin A inhibits the invasion of human oral squamous cell carcinoma by reducing metalloproteinase-9 mRNA stability and protein trafficking.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Female; Humans; Matrix Metalloproteinase 9; Mice; Mice, Nude; Mouth Neoplasms; Neoplasm Invasiveness; Oleanolic Acid; Protein Transport; RNA, Messenger; Saponins; Tetradecanoylphorbol Acetate; Tumor Burden; Xenograft Model Antitumor Assays

2012
Inhibitory effect of echinocystic acid on 12-O-tetradecanoylphorbol-13-acetate-induced dermatitis in mice.
    Archives of pharmacal research, 2014, Volume: 37, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Dermatitis; Macrophages, Peritoneal; Male; Mice; Mice, Inbred ICR; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Structure; Oleanolic Acid; Saponins; Spectrometry, Mass, Electrospray Ionization; Tetradecanoylphorbol Acetate

2014
Anti-inflammatory activity of different agave plants and the compound cantalasaponin-1.
    Molecules (Basel, Switzerland), 2013, Jul-10, Volume: 18, Issue:7

    Topics: Agave; Animals; Anti-Inflammatory Agents, Non-Steroidal; Edema; Male; Medicine, Traditional; Mice; Mice, Inbred ICR; Plant Leaves; Plant Preparations; Saponins; Tetradecanoylphorbol Acetate

2013
Platycodin D induces apoptosis, and inhibits adhesion, migration and invasion in HepG2 hepatocellular carcinoma cells.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Hep G2 Cells; Humans; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Medicine, Chinese Traditional; Neoplasm Invasiveness; Plant Extracts; Poly(ADP-ribose) Polymerases; Saponins; Survivin; Tetradecanoylphorbol Acetate; Triterpenes; Up-Regulation

2014
Saponins, especially platyconic acid A, from Platycodon grandiflorum reduce airway inflammation in ovalbumin-induced mice and PMA-exposed A549 cells.
    Journal of agricultural and food chemistry, 2015, Feb-11, Volume: 63, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Cell Line; Cytokines; Female; Humans; Lung; Matrix Metalloproteinase 2; Mice; Mice, Inbred ICR; Mucin 5AC; Ovalbumin; Plant Roots; Platycodon; Saponins; Tetradecanoylphorbol Acetate; Tissue Inhibitor of Metalloproteinase-1; Triterpenes

2015
Dioscin and methylprotodioscin isolated from the root of Asparagus cochinchinensis suppressed the gene expression and production of airway MUC5AC mucin induced by phorbol ester and growth factor.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, May-15, Volume: 22, Issue:5

    Topics: Asparagus Plant; Cell Line, Tumor; Diosgenin; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Mucin 5AC; Plant Roots; Saponins; Tetradecanoylphorbol Acetate

2015
Astragaloside IV inhibits PMA-induced EPCR shedding through MAPKs and PKC pathway.
    Immunopharmacology and immunotoxicology, 2017, Volume: 39, Issue:3

    Topics: Antigens, CD; Endothelial Protein C Receptor; Extracellular Signal-Regulated MAP Kinases; Human Umbilical Vein Endothelial Cells; Humans; MAP Kinase Signaling System; Protein Kinase C; Receptors, Cell Surface; Saponins; Tetradecanoylphorbol Acetate; Triterpenes

2017
Flavonoids and saponins from Passiflora edulis f. edulis leaves (purple passion fruit) and its potential anti-inflammatory activity.
    The Journal of pharmacy and pharmacology, 2021, Oct-07, Volume: 73, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Female; Flavonoids; Inflammation; Mice, Inbred ICR; Nitric Oxide Synthase; Passiflora; Phytotherapy; Plant Extracts; Plant Leaves; Saponins; Skin; Skin Diseases; Tandem Mass Spectrometry; Tetradecanoylphorbol Acetate

2021