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tetradecanoylphorbol acetate and ascorbic acid

tetradecanoylphorbol acetate has been researched along with ascorbic acid in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199011 (16.67)18.7374
1990's27 (40.91)18.2507
2000's19 (28.79)29.6817
2010's9 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gunther, GR; Jamieson, JD1
Avrova, NF; Tyurin, VA1
Abdalla, DS; Campa, A; Monteiro, HP1
Conney, AH; Deschner, EE; Ferraro, TA; Huang, MT; Newmark, HL; Wang, ZY1
Antczak, A; Nowak, D; Piasecka, G; Pietras, T1
Konttinen, YT; Lindy, O; Saari, H; Sorsa, T; Suomalainen, K; Uitto, VJ1
Frei, B1
Crawford, CL; Smart, RC1
Ghassibi, Y; Liau, DF; Ryan, SF1
Anderson, R; Joone, GK; Smit, MJ; Van Staden, AM1
Ames, BN; Cross, CE; Forte, T; Frei, B; Louie, S; Stocker, R; Yamamoto, Y1
Armato, U; Marchesini, C; Paccagnella, L; Romano, F1
Baxter, CS; Lawrence, AT1
Biggar, WD; Shear, NH; Uetrecht, J; Zahid, N1
Conney, AH; Focella, A; Han, ZT; Huang, MT; Kaplan, MC; Smart, RC1
Weitberg, AB; Weitzman, SA1
Boxer, LA; Pryzwansky, KB; Schliwa, M1
Stedman, DB; Welsch, F1
Birnboim, HC1
Vissers, MC; Winterbourn, CC1
Sivak, A; Tu, AS1
Biaglow, J; Kennedy, SH; Manevich, Y1
Barak-Shalom, T; Hurwitz, S; Knopov, V; Pines, M; Schickler, M; Shapira, R1
Chatterjee, IB; Mukhopadhyay, CK1
Aoki, K; Hattori, T; Kochi, M; Maruta, H; Nakashima, H; Ni-imi, E; Shiokawa, D; Tanimoto, Y; Uchiumi, F; Yamamoto, N1
Kim, YM; Piette, LH; Yamazaki, I1
Feuerstein, GZ; Gu, JL; Lysko, KA; Lysko, PG; Mckenna, PJ; Ruffolo, RR; Yue, TL1
Figala, V; Schmid, E; Ullrich, V1
Levine, M; Wang, Y; Washko, PW1
Rabgaoui, N; Slaoui-Hasnaoui, A; Torreilles, J1
Marquardt, H; Wölfle, D1
Harakeh, S; Jariwalla, RJ1
Ng, LL; Ngkeekwong, FC1
Maguire, JJ; Ogino, T; Packer, L1
Chain, BM; Foreman, JC; Tatla, S; Woodhead, V1
Agarwal, R; Chen, Y; Wang, J; Zhao, J1
Fabian, I; Fenig, E; Halperin, D; Kalir, HH; Kletter, Y; Nagler, A; Raviv, Z; Witenberg, B1
Daruwala, R; Koh, WS; Levine, M; Rumsey, SC; Song, J1
Kato-Masatsuji, E; Tsuchiya, T; Tsuzuki, T; Umeda, M1
Akao, S; Fujiwara, H; Fukuda, K; Ohno, Y; Yamashita, K1
Deby, CM; Deby-Dupont, GP; Henrotin, YE; Lamy, MM; Mouithys-Mickalad, AM; Reginster, JY; Zheng, SX1
Arkan, MC; Başağa, H; Biasi, F; Leonarduzzi, G; Poli, G1
De Bartolomeo, A; Fabiani, R; Morozzi, G; Rosignoli, P1
Furue, M; Goto, Y; Hayashi, H; Kogawa, N; Takahashi, O; Tsuchiya, M; Uchi, H; Watanabe, N1
Keilhoff, G; Noack, H; Possel, H; Wolf, G1
Bruchelt, G; Gerber, CE; Niethammer, D1
Godoy, AS; Golde, DW; Guaiquil, VH; Montecinos, VP; Nualart, FJ; Rivas, CI; Vera, JC1
Agarwal, A; Attaran, M; Falcone, T; Goldberg, JM; Sharma, RK; Wang, X1
Kang, NJ; Lee, CY; Lee, HJ; Lee, KW; Lee, SJ1
Ivanov, V; Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW1
Harris, AL; Knowles, HJ; Mole, DR; Ratcliffe, PJ1
Nantz, MP; Nieves, C; Percival, SS; Rowe, CA1
Johnston, L; Laverty, G1
Müller, C; Steege, A; Steinberg, P; Thierbach, R; Toyokuni, S; Ullmann, K; Wiencierz, AM1
Dahhan, T; Reidling, JC; Sadat, M; Said, HM; Subramanian, VS1
Hwang, YI; Jeong, YJ; Kang, JS; Lee, WJ; Lim, H; Maeng, HG; Woo, A1
Kalinovsky, T; Niedzwiecki, A; Rath, M; Roomi, MW; Roomi, NW1
Kalinovsky, T; Monterrey, JC; Niedzwiecki, A; Rath, M; Roomi, MW1
Cuddihy, SL; Parker, A; Son, TG; Vissers, MC; Winterbourn, CC1
Chapple, IL; Grant, MM; Griffiths, HR; Matthews, JB; Scott, AE; Wright, HJ1
Kimura, M; Moteki, H; Ogihara, M; Sunaga, K; Tsuda, T1
García-Robles, M; Godoy, AS; Godoy, DF; Martínez, F; Nualart, F; Pérez, F; Reinicke, K; Salazar, K; Ulloa, V1
Behnen, M; Hermann, E; Kirchner, T; Klinger, M; Laskay, T; Möller, S; Solbach, W1
Abbas, K; Hardy, M; Karoui, H; Ouari, O; Peyrot, F; Poulhès, F; Tordo, P1
Capó, X; Martorell, M; Pons, A; Sureda, A; Tur, JA1
Chang, WJ; Chen, C; Chen, JN; Hung, YT; Wang, HF; Wei, CW; Wu, TK; Yiang, GT; Yu, YL1

Trials

2 trial(s) available for tetradecanoylphorbol acetate and ascorbic acid

ArticleYear
Immunity and antioxidant capacity in humans is enhanced by consumption of a dried, encapsulated fruit and vegetable juice concentrate.
    The Journal of nutrition, 2006, Volume: 136, Issue:10

    Topics: Adult; Antioxidants; Ascorbic Acid; Beverages; Carotenoids; Cytokines; DNA Damage; Double-Blind Method; Female; Food Preservation; Fruit; Humans; Immunity; Interferon-gamma; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Placebos; T-Lymphocytes; Tetradecanoylphorbol Acetate; Vegetables

2006
Effects of docosahexaenoic supplementation and in vitro vitamin C on the oxidative and inflammatory neutrophil response to activation.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Ascorbic Acid; Catalase; Dietary Supplements; Docosahexaenoic Acids; Erythrocytes; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Male; Neutrophil Activation; Neutrophils; Nitrates; Nitrites; Oxidative Stress; Peroxidase; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Young Adult

2015

Other Studies

64 other study(ies) available for tetradecanoylphorbol acetate and ascorbic acid

ArticleYear
Increased intracellular cyclic GMP does not correlate with protein discharge from pancreatic acinar cells.
    Nature, 1979, Jul-26, Volume: 280, Issue:5720

    Topics: Animals; Ascorbic Acid; Cyclic GMP; Dehydroascorbic Acid; Guinea Pigs; Hydroxylamines; Methylnitronitrosoguanidine; Methylnitrosourea; Nitroprusside; Pancreas; Proteins; Sodium Nitrite; Tetradecanoylphorbol Acetate

1979
Ganglioside-dependent factor, inhibiting lipid peroxidation in rat brain synaptosomes.
    Neurochemistry international, 1992, Volume: 20, Issue:3

    Topics: Animals; Ascorbic Acid; Cerebral Cortex; Ferric Compounds; G(M1) Ganglioside; Gangliosides; Kinetics; Lipid Peroxidation; Rats; Rats, Wistar; Synaptosomes; Tetradecanoylphorbol Acetate; Time Factors; Vitamin E

1992
Low density lipoprotein oxidation by stimulated neutrophils and ferritin.
    Atherosclerosis, 1992, Volume: 97, Issue:2-3

    Topics: Apoproteins; Ascorbic Acid; Catalase; Ceruloplasmin; Ferritins; Humans; Lipid Peroxidation; Lipoproteins, LDL; Methionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Superoxides; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Transferrin; Uric Acid

1992
Effect of dietary curcumin and ascorbyl palmitate on azoxymethanol-induced colonic epithelial cell proliferation and focal areas of dysplasia.
    Cancer letters, 1992, Jun-15, Volume: 64, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Body Weight; Colon; Curcumin; Diet; Epithelium; Female; Methylazoxymethanol Acetate; Mice; Tetradecanoylphorbol Acetate

1992
Effect of ascorbic acid on hydroxyl radical generation by chemical, enzymatic and cellular systems. Importance for antioxidant prevention of pulmonary emphysema.
    Biomedica biochimica acta, 1991, Volume: 50, Issue:3

    Topics: Animals; Antioxidants; Ascorbic Acid; Deoxyribose; Dithiothreitol; Edetic Acid; Ferrous Compounds; Free Radicals; Glutathione; Hydroxides; Hydroxyl Radical; Macrophages; Male; Mannitol; Mercaptoethanol; Mice; Neutrophils; Oxidation-Reduction; Pulmonary Emphysema; Tetradecanoylphorbol Acetate; Xanthine Oxidase

1991
Hypochlorous acid induced activation of human neutrophil and gingival crevicular fluid collagenase can be inhibited by ascorbate.
    Scandinavian journal of dental research, 1991, Volume: 99, Issue:5

    Topics: Ascorbic Acid; Chymotrypsin; Enzyme Activation; Gingival Crevicular Fluid; Humans; Hypochlorous Acid; Microbial Collagenase; Neutrophils; Oxidation-Reduction; Tetradecanoylphorbol Acetate; Trypsin

1991
Ascorbic acid protects lipids in human plasma and low-density lipoprotein against oxidative damage.
    The American journal of clinical nutrition, 1991, Volume: 54, Issue:6 Suppl

    Topics: Amidines; Ascorbic Acid; Free Radicals; Humans; Lipid Metabolism; Lipid Peroxides; Lipids; Lipoproteins, LDL; Neutrophils; Nicotiana; Oxidation-Reduction; Peroxides; Plants, Toxic; Smoke; Tetradecanoylphorbol Acetate

1991
Effect of ascorbic acid and its synthetic lipophilic derivative ascorbyl palmitate on phorbol ester-induced skin-tumor promotion in mice.
    The American journal of clinical nutrition, 1991, Volume: 54, Issue:6 Suppl

    Topics: Animals; Ascorbic Acid; Diet; DNA; Epidermis; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Osmolar Concentration; Skin Neoplasms; Tetradecanoylphorbol Acetate

1991
Effects of activated polymorphonuclear leukocytes upon pulmonary surfactant in vitro.
    American journal of respiratory cell and molecular biology, 1991, Volume: 4, Issue:1

    Topics: Adsorption; Animals; Ascorbic Acid; Centrifugation, Isopycnic; Chlorides; Dogs; Electrophoresis, Polyacrylamide Gel; Ferric Compounds; Humans; Kinetics; Lymphocyte Activation; Male; Neutrophils; Pulmonary Surfactants; Superoxide Dismutase; Surface Tension; Tetradecanoylphorbol Acetate

1991
Vitamin C and cellular immune functions. Protection against hypochlorous acid-mediated inactivation of glyceraldehyde-3-phosphate dehydrogenase and ATP generation in human leukocytes as a possible mechanism of ascorbate-mediated immunostimulation.
    Annals of the New York Academy of Sciences, 1990, Volume: 587

    Topics: Adenosine Triphosphate; Antioxidants; Ascorbic Acid; Glucose; Glyceraldehyde 3-Phosphate; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunity, Cellular; Immunization; Lymphocyte Activation; Mitogens; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sulfhydryl Compounds; Superoxides; Tetradecanoylphorbol Acetate

1990
Oxidative stress and abnormal cholesterol metabolism in patients with adult respiratory distress syndrome.
    The Journal of laboratory and clinical medicine, 1990, Volume: 115, Issue:4

    Topics: Adult; Aged; Antioxidants; Ascorbic Acid; Cholesterol; Cholesterol Esters; Exudates and Transudates; Female; Humans; Lipid Peroxides; Luminescent Measurements; Male; Middle Aged; Neutrophils; Oxidation-Reduction; Oxygen; Pulmonary Edema; Respiratory Distress Syndrome; Tetradecanoylphorbol Acetate; Ubiquinone; Vitamin E

1990
Antioxidants and blockers of arachidonate metabolism inhibit the mitogenic effects of TPA in hepatocytes: differences in the operative mechanisms according to the cell cycle setting.
    Cell biology international reports, 1986, Volume: 10, Issue:10

    Topics: Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Cell Cycle; Glutathione; Kinetics; Lipoxygenase; Liver; Mitosis; Rats; Tetradecanoylphorbol Acetate; Thromboxane-A Synthase; Vitamin E

1986
Specific inhibition of phorbol diester-induced granulocyte-macrophage progenitor cell (GM-CFU) differentiation by lipoxygenase inhibitors.
    Cancer letters, 1987, Volume: 37, Issue:3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Butylated Hydroxyanisole; Cell Differentiation; Colony-Forming Units Assay; Dexamethasone; Granulocytes; Hematopoietic Stem Cells; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Tetradecanoylphorbol Acetate

1987
Metabolism of dapsone to a hydroxylamine by human neutrophils and mononuclear cells.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1

    Topics: Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Azides; Catalase; Cyclooxygenase Inhibitors; Dapsone; Humans; Hydroxylamine; Hydroxylamines; Indomethacin; Leukocytes, Mononuclear; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan

1988
Inhibition of 12-O-tetradecanoylphorbol-13-acetate induction of ornithine decarboxylase activity, DNA synthesis, and tumor promotion in mouse skin by ascorbic acid and ascorbyl palmitate.
    Cancer research, 1987, Dec-15, Volume: 47, Issue:24 Pt 1

    Topics: Administration, Topical; Animals; Ascorbic Acid; Diglycerides; DNA Replication; Drug Interactions; Enzyme Induction; Female; Mice; Ornithine Decarboxylase; Palmitic Acid; Palmitic Acids; Skin Neoplasms; Tetradecanoylphorbol Acetate

1987
The effect of vitamin C on oxygen radical-induced sister-chromatid exchanges.
    Mutation research, 1985, Volume: 144, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Cell Line; Cricetinae; Cricetulus; Drug Interactions; Female; Fibroblasts; Free Radicals; Humans; Hypoxanthine; Hypoxanthines; Leukocytes; Ovary; Oxidation-Reduction; Oxygen; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate; Xanthine Oxidase

1985
Microtubule organization of unstimulated and stimulated adherent human neutrophils in Chediak-Higashi syndrome.
    Blood, 1985, Volume: 66, Issue:6

    Topics: Ascorbic Acid; Cell Adhesion; Cell Separation; Cells, Cultured; Chediak-Higashi Syndrome; Child; Female; Humans; Microtubules; Neutrophils; Tetradecanoylphorbol Acetate

1985
Inhibition of metabolic cooperation between Chinese hamster V79 cells by structurally diverse teratogens.
    Teratogenesis, carcinogenesis, and mutagenesis, 1984, Volume: 4, Issue:3

    Topics: Animals; Ascorbic Acid; Cell Communication; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; Ethylene Glycols; Lung; Mutation; Phenytoin; Saccharin; Teratogens; Tetradecanoylphorbol Acetate; Warfarin

1984
Factors which affect DNA strand breakage in human leukocytes exposed to a tumor promoter, phorbol myristate acetate.
    Canadian journal of physiology and pharmacology, 1982, Volume: 60, Issue:11

    Topics: Ascorbic Acid; Disulfiram; Ditiocarb; DNA; Glucose; Humans; In Vitro Techniques; Leukocyte Count; Leukocytes; Oxidation-Reduction; Phorbols; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate

1982
Changes in ascorbate levels on stimulation of human neutrophils.
    Biochimica et biophysica acta, 1983, Sep-22, Volume: 763, Issue:2

    Topics: Ascorbic Acid; Cytochalasin B; Dehydroascorbic Acid; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Zymosan

1983
Cell culture tumor promotion experiments with saccharin, phorbol myristate acetate and several common food materials.
    Cancer letters, 1980, Volume: 10, Issue:1

    Topics: Animals; Ascorbic Acid; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Pantothenic Acid; Phorbols; Saccharin; Tetradecanoylphorbol Acetate; Tryptophan

1980
Benzoyl peroxide acts as a promoter of radiation induced malignant transformation in vitro.
    Biochemical and biophysical research communications, 1995, Jul-06, Volume: 212, Issue:1

    Topics: Animals; Ascorbic Acid; Benzoyl Peroxide; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Radiation; Free Radicals; Hydroxyl Radical; Hydroxylation; Iron; Kinetics; Mice; Radiation-Sensitizing Agents; Tetradecanoylphorbol Acetate; X-Rays

1995
Synthesis and phosphorylation of osteopontin by avian epiphyseal growth-plate chondrocytes as affected by differentiation.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1995, Volume: 111, Issue:1

    Topics: Alkaline Phosphatase; Amino Acid Sequence; Animals; Ascorbic Acid; Blotting, Northern; Bone Development; Cell Differentiation; Cell Division; Cells, Cultured; Chickens; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Growth Plate; In Situ Hybridization; Molecular Sequence Data; Osteopontin; Parathyroid Hormone; Phosphoproteins; Phosphorylation; RNA, Messenger; Sialoglycoproteins; Tetradecanoylphorbol Acetate; Tibia

1995
Free metal ion-independent oxidative damage of collagen. Protection by ascorbic acid.
    The Journal of biological chemistry, 1994, Dec-02, Volume: 269, Issue:48

    Topics: Animals; Ascorbic Acid; Catalase; Cattle; Collagen; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Free Radical Scavengers; Guinea Pigs; Iron; Kinetics; Macrophage Activation; Macrophages, Peritoneal; Male; Metals; Peptide Fragments; Peptides; Superoxides; Tetradecanoylphorbol Acetate; Xanthine Oxidase

1994
Sodium benzylideneascorbate induces apoptosis in HIV-replicating U1 cells.
    FEBS letters, 1994, Aug-29, Volume: 351, Issue:1

    Topics: Antiviral Agents; Apoptosis; Ascorbic Acid; Benzylidene Compounds; HIV Antigens; HIV-1; Humans; Molecular Structure; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Virus Replication

1994
The effect of hemoglobin, hematin, and iron on neutrophil inactivation in superoxide generating systems.
    Archives of biochemistry and biophysics, 1994, Volume: 309, Issue:2

    Topics: Adult; Animals; Ascorbic Acid; Blood Bactericidal Activity; Catalase; Cattle; Cyclic N-Oxides; Edetic Acid; Escherichia coli; Ferric Compounds; Free Radical Scavengers; Hemin; Hemoglobins; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Neutrophils; Superoxides; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances

1994
SB 211475, a metabolite of carvedilol, a novel antihypertensive agent, is a potent antioxidant.
    European journal of pharmacology, 1994, Jan-14, Volume: 251, Issue:2-3

    Topics: Adenosine Diphosphate; Animals; Antihypertensive Agents; Antioxidants; Ascorbic Acid; Brain; Carbazoles; Cattle; Cell Death; Cells, Cultured; Chromans; Endothelium, Vascular; Fumarates; Humans; Iron; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Male; Mice; Neurons; Neutrophils; Nicardipine; Oxidation-Reduction; Piperazines; Propanolamines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines

1994
Inhibition of NADPH-oxidase activity in human polymorphonuclear neutrophils by lipophilic ascorbic acid derivatives.
    Molecular pharmacology, 1994, Volume: 45, Issue:5

    Topics: Amino Acid Sequence; Arachidonic Acid; Ascorbic Acid; Calcium; Guanine Nucleotides; Humans; In Vitro Techniques; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate

1994
Ascorbic acid recycling in human neutrophils.
    The Journal of biological chemistry, 1993, Jul-25, Volume: 268, Issue:21

    Topics: Adult; Antioxidants; Ascorbic Acid; Catalase; Cells, Cultured; Dehydroascorbic Acid; Humans; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Sodium Fluoride; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Xanthine; Xanthine Oxidase; Xanthines

1993
Boomerang effect between [Met]-enkephalin derivatives and human polymorphonuclear leukocytes.
    Free radical biology & medicine, 1993, Volume: 14, Issue:5

    Topics: Amino Acid Sequence; Ascorbic Acid; Chromatography, High Pressure Liquid; Copper; Enkephalin, Methionine; Free Radicals; Humans; Hydroxylation; Luminescent Measurements; Methionine; Molecular Sequence Data; Neutrophils; Oxidation-Reduction; Phenylalanine; Protein Precursors; Reactive Oxygen Species; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate

1993
Antioxidants inhibit the enhancement of malignant cell transformation induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Carcinogenesis, 1996, Volume: 17, Issue:6

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Carcinogens; Cell Transformation, Neoplastic; Drug Interactions; Enzyme Inhibitors; Fibroblasts; Isoquinolines; Mannitol; Methylnitronitrosoguanidine; Mice; Mice, Inbred C3H; Piperazines; Polychlorinated Dibenzodioxins; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Vitamin E

1996
NF-kappa B-independent suppression of HIV expression by ascorbic acid.
    AIDS research and human retroviruses, 1997, Feb-10, Volume: 13, Issue:3

    Topics: Acetylcysteine; Ascorbic Acid; Cell Line; HIV; Humans; Hydrogen Peroxide; NF-kappa B; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha; Virus Latency; Virus Replication

1997
Two distinct uptake mechanisms for ascorbate and dehydroascorbate in human lymphoblasts and their interaction with glucose.
    The Biochemical journal, 1997, May-15, Volume: 324 ( Pt 1)

    Topics: Ascorbic Acid; Biological Transport; Cells, Cultured; Dehydroascorbic Acid; Diffusion; Dithiothreitol; Humans; Kinetics; Lymphocytes; Temperature; Tetradecanoylphorbol Acetate

1997
Neutrophil antioxidant capacity during the respiratory burst: loss of glutathione induced by chloramines.
    Free radical biology & medicine, 1997, Volume: 23, Issue:3

    Topics: Animals; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Cell Membrane Permeability; Cell Survival; Chloramines; Enzyme Inhibitors; Glutathione; Hydrogen Peroxide; Male; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; Respiratory Burst; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Vitamin E

1997
The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells.
    Free radical biology & medicine, 1999, Volume: 26, Issue:1-2

    Topics: Antibodies, Monoclonal; Antigen-Presenting Cells; Antioxidants; Ascorbic Acid; Calcimycin; CD28 Antigens; Cell Division; Deferoxamine; Dimethyl Sulfoxide; Humans; In Vitro Techniques; Interleukin-2; Ionophores; Lymphocyte Activation; Reactive Oxygen Species; Second Messenger Systems; T-Lymphocytes; Tetradecanoylphorbol Acetate

1999
Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Cutaneous; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Biflavonoids; Catechin; Cocarcinogenesis; Epidermis; Female; Flavonoids; Lipid Peroxidation; Mice; Mice, Inbred SENCAR; Microsomes; Molecular Structure; Phenols; Plant Extracts; Polymers; Proanthocyanidins; Rosales; Seeds; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin E

1999
Ascorbic acid inhibits apoptosis induced by X irradiation in HL60 myeloid leukemia cells.
    Radiation research, 1999, Volume: 152, Issue:5

    Topics: Apoptosis; Ascorbic Acid; fas Receptor; HL-60 Cells; Humans; Leukemia, Myeloid; Peroxides; Proto-Oncogene Proteins c-bcl-2; Tetradecanoylphorbol Acetate; Up-Regulation; X-Rays

1999
Cloning and functional characterization of the human sodium-dependent vitamin C transporters hSVCT1 and hSVCT2.
    FEBS letters, 1999, Nov-05, Volume: 460, Issue:3

    Topics: Amino Acid Sequence; Animals; Ascorbic Acid; Base Sequence; Biological Transport; Bucladesine; Carrier Proteins; Cloning, Molecular; Female; Humans; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Dependent; Protein Biosynthesis; Proteins; Sodium; Sodium-Coupled Vitamin C Transporters; Symporters; Tetradecanoylphorbol Acetate; Xenopus laevis

1999
Anti-transforming nature of ascorbic acid and its derivatives examined by two-stage cell transformation using BALB/c 3T3 cells.
    Cancer letters, 2000, Nov-10, Volume: 160, Issue:1

    Topics: 3T3 Cells; Animals; Ascorbic Acid; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Methylcholanthrene; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha

2000
Inhibition by costunolide of phorbol ester-induced transcriptional activation of inducible nitric oxide synthase gene in a human monocyte cell line THP-1.
    Cancer letters, 2001, Mar-10, Volume: 164, Issue:1

    Topics: Anticarcinogenic Agents; Ascorbic Acid; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Gallic Acid; Genes, Reporter; Humans; Inhibitory Concentration 50; Luciferases; Monocytes; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phorbol Esters; Promoter Regions, Genetic; Protein Kinase C; Sesquiterpenes; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Transcriptional Activation; Vitamin E

2001
In vitro study of the antioxidant properties of non steroidal anti-inflammatory drugs by chemiluminescence and electron spin resonance (ESR).
    Free radical research, 2000, Volume: 33, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Chlorine; Diclofenac; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; In Vitro Techniques; Indicators and Reagents; Indomethacin; Iron; Kinetics; Lipid Peroxidation; Luminescent Measurements; Neutrophil Activation; Neutrophils; Nitrates; Reactive Oxygen Species; Sodium Hypochlorite; Spectrophotometry, Ultraviolet; Sulfonamides; Tetradecanoylphorbol Acetate

2000
Physiological amounts of ascorbate potentiate phorbol ester-induced nuclear-binding of AP-1 transcription factor in cells of macrophagic lineage.
    Free radical biology & medicine, 2001, Aug-01, Volume: 31, Issue:3

    Topics: Animals; Ascorbic Acid; Cell Line; Cell Nucleus; Cycloheximide; Deferoxamine; Dimerization; Drug Synergism; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidation-Reduction; Protein Subunits; Proto-Oncogene Proteins c-jun; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2001
Antioxidants prevent the lymphocyte DNA damage induced by PMA-stimulated monocytes.
    Nutrition and cancer, 2001, Volume: 39, Issue:2

    Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; beta Carotene; DNA Damage; HL-60 Cells; Humans; Hydrogen Peroxide; Lymphocytes; Monocytes; Quercetin; Respiratory Burst; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate

2001
CX-659S: a novel diaminouracil derivative that has antioxidative and acute anti-inflammatory activities.
    European journal of pharmacology, 2002, Mar-08, Volume: 438, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Ascorbic Acid; Chromans; Dose-Response Relationship, Drug; Ear; Edema; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Oxidation-Reduction; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Uracil

2002
Life imaging of peroxynitrite in rat microglial and astroglial cells: Role of superoxide and antioxidants.
    Glia, 2002, Volume: 38, Issue:4

    Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Astrocytes; Cells, Cultured; Encephalitis; Enzyme Inhibitors; Fluorescent Antibody Technique; Fluorescent Dyes; Glutathione; Interferon-gamma; Lipopolysaccharides; Microglia; NADPH Oxidases; Neurodegenerative Diseases; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Wistar; Superoxides; Tetradecanoylphorbol Acetate

2002
Differences in the accumulation of ascorbic acid in normal, myeloperoxidase deficient and NADPH-oxidase deficient granulocytes.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 2002, Volume: 72, Issue:4

    Topics: Antioxidants; Ascorbic Acid; Cells, Cultured; Erythrocytes; Granulocytes; Humans; NADPH Oxidases; Peroxidase; Tetradecanoylphorbol Acetate

2002
Recycling of vitamin C by a bystander effect.
    The Journal of biological chemistry, 2003, Mar-21, Volume: 278, Issue:12

    Topics: Ascorbic Acid; Cytochalasin B; Dehydroascorbic Acid; Glucose; Humans; Neutrophils; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2003
Vitamin C and vitamin E supplementation reduce oxidative stress-induced embryo toxicity and improve the blastocyst development rate.
    Fertility and sterility, 2002, Volume: 78, Issue:6

    Topics: Animals; Antioxidants; Ascorbic Acid; Culture Techniques; Embryo, Mammalian; Embryonic and Fetal Development; Female; Humans; Mice; Oxidative Stress; Prospective Studies; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Vitamin E

2002
Effects of phenolics in Empire apples on hydrogen peroxide-induced inhibition of gap-junctional intercellular communication.
    BioFactors (Oxford, England), 2004, Volume: 21, Issue:1-4

    Topics: Antioxidants; Ascorbic Acid; Catechin; Cell Communication; Chromatography, High Pressure Liquid; Gap Junctions; HL-60 Cells; Humans; Hydrogen Peroxide; Malus; Phenols; Quercetin; Tetradecanoylphorbol Acetate

2004
Antitumor effect of nutrient synergy on human osteosarcoma cells U-2OS, MNNG-HOS and Ewing's sarcoma SK-ES.1.
    Oncology reports, 2005, Volume: 13, Issue:2

    Topics: Arginine; Ascorbic Acid; Bone Neoplasms; Catechin; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Lysine; Matrix Metalloproteinases; Neovascularization, Pathologic; Nutritional Physiological Phenomena; Osteosarcoma; Proline; Sarcoma, Ewing; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2005
Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1.
    Cancer research, 2006, Mar-01, Volume: 66, Issue:5

    Topics: Ascorbic Acid; Cation Transport Proteins; Cell Differentiation; Cell Line, Tumor; Ferrous Compounds; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Iron; Macrophages; Oxygen; Tetradecanoylphorbol Acetate; U937 Cells; Up-Regulation

2006
Vitamin C transport and SVCT1 transporter expression in chick renal proximal tubule cells in culture.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2007, Volume: 146, Issue:3

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Ascorbic Acid; Cells, Cultured; Chickens; Electrophysiology; Gene Expression Regulation; Humans; Kidney Tubules, Proximal; Nitrobenzoates; Organic Anion Transporters, Sodium-Dependent; Quercetin; Sodium-Coupled Vitamin C Transporters; Symporters; Tetradecanoylphorbol Acetate

2007
A high-throughput reporter gene assay to prove the ability of natural compounds to modulate glutathione peroxidase, superoxide dismutase and catalase gene promoters in V79 cells.
    Free radical research, 2008, Volume: 42, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Carcinogens; Carnitine; Catalase; Catechin; Cells, Cultured; Chromans; Cricetinae; Cricetulus; Genistein; Glutathione Peroxidase; Herbicides; Humans; Luciferases; Paraquat; Promoter Regions, Genetic; Quercetin; Rats; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Vitamin B Complex

2008
Mechanisms and regulation of vitamin C uptake: studies of the hSVCT systems in human liver epithelial cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 295, Issue:6

    Topics: Ascorbic Acid; Budesonide; Cell Line, Tumor; Dehydroascorbic Acid; Dexamethasone; Epithelial Cells; Gene Expression Regulation; Hepatocytes; Humans; Liver; Mifepristone; Organic Anion Transporters, Sodium-Dependent; Promoter Regions, Genetic; Protein Kinase C; RNA, Small Interfering; Sodium-Coupled Vitamin C Transporters; Symporters; Tetradecanoylphorbol Acetate; Transfection

2008
Vitamin C enters mouse T cells as dehydroascorbic acid in vitro and does not recapitulate in vivo vitamin C effects.
    Immunobiology, 2009, Volume: 214, Issue:4

    Topics: Animals; Ascorbic Acid; Biological Transport; Cell Proliferation; Cell Survival; Cytokines; Dehydroascorbic Acid; Dithiothreitol; Glucose Transporter Type 1; Glucose Transporter Type 3; Immunomagnetic Separation; Ionomycin; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Oxidation-Reduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine

2009
Marked inhibition of growth and invasive parameters of head and neck squamous carcinoma FaDu by a nutrient mixture.
    Integrative cancer therapies, 2009, Volume: 8, Issue:2

    Topics: Administration, Oral; Amino Acids; Animals; Apoptosis; Ascorbic Acid; Camellia sinensis; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Survival; Complementary Therapies; Food; Head and Neck Neoplasms; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Nude; Neoplasm Invasiveness; Plant Extracts; Tetradecanoylphorbol Acetate; Xenograft Model Antitumor Assays

2009
Comparative effects of EGCG, green tea and a nutrient mixture on the patterns of MMP-2 and MMP-9 expression in cancer cell lines.
    Oncology reports, 2010, Volume: 24, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Ascorbic Acid; Camellia sinensis; Catechin; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Lysine; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Micronutrients; Neoplasm Invasiveness; Neoplasms; Plant Extracts; Proline; Protease Inhibitors; Tetradecanoylphorbol Acetate

2010
Roles of superoxide and myeloperoxidase in ascorbate oxidation in stimulated neutrophils and H2O2-treated HL60 cells.
    Free radical biology & medicine, 2011, Oct-01, Volume: 51, Issue:7

    Topics: Antioxidants; Ascorbic Acid; Catalase; Enzyme Inhibitors; Glutathione; HL-60 Cells; Humans; Hydrogen Peroxide; Hypochlorous Acid; Neutrophils; Organ Specificity; Oxidation-Reduction; Oxidative Stress; Peroxidase; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate

2011
Ascorbate and α-tocopherol differentially modulate reactive oxygen species generation by neutrophils in response to FcγR and TLR agonists.
    Innate immunity, 2013, Volume: 19, Issue:2

    Topics: Adult; alpha-Tocopherol; Ascorbic Acid; Cells, Cultured; Female; Fusobacterium nucleatum; Humans; Male; Micronutrients; Middle Aged; Neutrophils; Periodontitis; Reactive Oxygen Species; Receptors, IgG; Staphylococcus aureus; Tetradecanoylphorbol Acetate; Toll-Like Receptors; Young Adult

2013
Signal transduction mechanism for potentiation by α1- and β2-adrenoceptor agonists of L-ascorbic acid-induced DNA synthesis and proliferation in primary cultures of adult rat hepatocytes.
    European journal of pharmacology, 2013, Jan-30, Volume: 700, Issue:1-3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Animals; Ascorbic Acid; Cell Proliferation; Cells, Cultured; DNA; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Hepatocytes; Male; Metaproterenol; Phenylephrine; Phosphorylation; Rats; Rats, Wistar; Receptor, IGF Type 1; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-2; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors

2013
Human choroid plexus papilloma cells efficiently transport glucose and vitamin C.
    Journal of neurochemistry, 2013, Volume: 127, Issue:3

    Topics: Ascorbic Acid; Biological Transport, Active; Bystander Effect; Cell Membrane; Choroid Plexus Neoplasms; Dehydroascorbic Acid; Glucose; Glucose Transporter Type 1; Humans; Immunohistochemistry; Neutrophils; Papilloma, Choroid Plexus; Primary Cell Culture; Real-Time Polymerase Chain Reaction; Sodium-Coupled Vitamin C Transporters; Tetradecanoylphorbol Acetate

2013
Flavonoids and 5-aminosalicylic acid inhibit the formation of neutrophil extracellular traps.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Ascorbic Acid; Cells, Cultured; Chemotaxis, Leukocyte; Flavonoids; Humans; Mesalamine; NADPH Oxidases; Neutrophils; Peroxidase; Phagocytosis; Reactive Oxygen Species; Tetradecanoylphorbol Acetate

2013
Detection of superoxide production in stimulated and unstimulated living cells using new cyclic nitrone spin traps.
    Free radical biology & medicine, 2014, Volume: 71

    Topics: Animals; Ascorbic Acid; Cell Line; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Macrophage Activation; Macrophages; Mice; Nitrogen Oxides; Spin Labels; Spin Trapping; Superoxides; Tetradecanoylphorbol Acetate

2014
Ascorbic acid inhibits TPA-induced HL-60 cell differentiation by decreasing cellular H₂O₂ and ERK phosphorylation.
    Molecular medicine reports, 2015, Volume: 12, Issue:4

    Topics: Ascorbic Acid; Caspases; Cell Differentiation; Cell Proliferation; Cell Survival; Extracellular Signal-Regulated MAP Kinases; HL-60 Cells; Humans; Hydrogen Peroxide; Macrophages; Phosphorylation; Tetradecanoylphorbol Acetate

2015