tetradecanoylphorbol acetate has been researched along with 9,10-dimethyl-1,2-benzanthracene in 870 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 219 (25.17) | 18.7374 |
| 1990's | 278 (31.95) | 18.2507 |
| 2000's | 207 (23.79) | 29.6817 |
| 2010's | 152 (17.47) | 24.3611 |
| 2020's | 14 (1.61) | 2.80 |
| Authors | Studies |
|---|---|
| Brune, K; Hecker, E; Kalin, H; Schmidt, R | 1 |
| Chouroulinkov, I; Lasne, C | 1 |
| Goerttler, K; Loehrke, H; Schweizer, J | 1 |
| Knowles, MA | 1 |
| Goerttler, K; Hesse, B; Loehrke, H; Schweizer, J | 7 |
| DiGiovanni, J; Gleason, GL; Harvey, RG; Slaga, TJ; Sukumaran, KB | 1 |
| Melchionne, S; Segal, A; Seidman, I; Smith, AC; Tseng, SS; Van Duuren, BL | 1 |
| Fisher, PB; Goldstein, NI; Weinstein, IB | 1 |
| Bracken, WM; Gleason, GL; Hennings, H; Slaga, TJ; Weeks, CE | 1 |
| Stenbäck, F | 3 |
| Nettesheim, P; Terzaghi, M | 1 |
| Chouroulinkov, I; Gentil, A; Grover, PL; Sims, P; Tierney, B | 1 |
| Boukamp, HK; Worst, PK | 1 |
| Armuth, V; Berenblum, I | 1 |
| Goerttler, K; Löhrke, H | 1 |
| Berry, DL; DiGiovanni, J; Juchau, MR; Slaga, TJ | 1 |
| Argyris, TS; De Young, LM; Gordon, GB | 1 |
| Marks, F; Schweizer, J | 1 |
| Goerttler, K; Komitowski, D; Löhrke, H | 1 |
| Griesemer, RA; Nelson, FR; Nettesheim, P; Pal, BC; Topping, DC | 1 |
| Segal, A; Van Duuren, BL | 1 |
| Albert, RE; Burns, FJ; Sivak, A; Vanderlaan, M | 1 |
| Brankow, DW; Heidelberger, C; Mondal, S | 1 |
| Palmes, ED | 1 |
| Scribner, JD; Slaga, TJ; Viaje, A | 1 |
| Goerttler, K; Loehrke, H | 3 |
| Gimenez-Conti, IB; Slaga, TJ | 1 |
| Iwashima, A; Kokumai, M; Konoshima, T; Kozuka, M; Nishino, H; Tokuda, H | 1 |
| Daniels, MJ; Dean, JH; Selgrade, MK | 1 |
| Inohara, S | 1 |
| Bianchi, AB; Conti, CJ; Fischer, SM; Gimenez-Conti, IB; Reiners, JJ; Slaga, TJ | 1 |
| Ballestín, C; Bauluz, C; Conti, CJ; Díaz-Guerra, M; Jorcano, JL; Larcher, F; Quintanilla, M | 1 |
| Bickers, DR; Elmets, CA; Mukhtar, H; Zaidi, SI | 1 |
| Hasegawa, T; Iwashima, A; Kitano, H; Murakoshi, M; Nishino, H; Okabe, H; Okuzumi, J; Satomi, Y; Takayasu, J; Tokuda, H | 1 |
| Chang, R; Conney, AH; Ferraro, T; Ho, CT; Huang, MT; Ma, W; Reuhl, KR; Wang, ZY; Yang, CS | 1 |
| Pelling, JC; Strawhecker, JM | 1 |
| Aguelon, AM; Nakazawa, H; Yamasaki, H | 1 |
| Chen, LC; De Luca, LM; Jones, CS; Sly, L | 1 |
| Agarwal, R; Katiyar, SK; Mukhtar, H; Wood, GS | 1 |
| Mesnil, M; Nakazawa, H; Yamasaki, H | 1 |
| Dwivedi, C; Engineer, FN; Jarvis, D; Rohlfs, S | 1 |
| Kato, R; Wang, JC; Yamamoto, S | 1 |
| Gensler, HL; Powell, MB; Simpson, PJ | 1 |
| Burnett, R; Goddard, M; Lecuyer, DW; McLean, JR; Mitchel, RE; Stuchly, MA | 1 |
| Alhonen, L; Halmekytö, M; Jänne, J; Syrjänen, K | 1 |
| Adams, AK; Hanausek, M; Mirowski, M; Sherman, U; Slaga, TJ; Walaszek, Z | 1 |
| Barnett, T; Birt, DF; Enkvetchakul, B; Geisler, V; Liotta, DC; Menaldino, D; Merrill, AH | 1 |
| Antony, M; Mehrotra, NK; Shukla, Y | 1 |
| Hennings, H; Strickland, JE; Ueda, M; Yuspa, SH | 1 |
| Birt, DF; Choe, M; Kris, ES; Pelling, JC | 1 |
| Bechtel, DH; Belury, MA; Fischer, SM; Lee, ML; Leyton, J; Locniskar, M; Maldve, RE; Slaga, TJ | 1 |
| Boone, CW; Kelloff, GJ; Steele, VE | 2 |
| Ferraro, T; Finnegan-Olive, T; Ho, CT; Huang, MT; Laskin, JD; Lou, YR; Mitchell, JM; Newmark, H; Wang, ZY; Yang, CS | 1 |
| Kopp-Schneider, A; Portier, CJ | 2 |
| Tabara, M; Watanabe, M | 4 |
| Bocckino, SB; Burns, DJ; Loomis, CR; Mills, KJ; Smart, RC | 1 |
| Bonham, K; Bowden, GT; Krieg, P; Ostrowski, LE | 1 |
| Aldaz, CM; Chiba, M; Conti, CJ; Klein-Szanto, AJ | 1 |
| Austin, SJ; Beeman, DK; Lasley, JA; Mass, MJ; Schorschinsky, NS | 2 |
| Nischt, R; Rentrop, M; Schweizer, J; Winter, H | 1 |
| Fürstenberger, G; Krieg, P; Marks, F; Schnapke, R; Vogt, I | 1 |
| Andrews, K; Bowden, GT; Finch, J; Fürstenberger, G; Krieg, P; Ootsuyama, A; Slaga, T; Tanooka, H | 1 |
| Clausen, OP; Heyden, A; Huitfeldt, HS; Roop, D; Thrane, EV; Yuspa, SH | 1 |
| Schweizer, J; Strickland, JE; Sutter, C; Welty, DJ; Winter, H; Yuspa, SH | 1 |
| Meyer, SA; Moser, GJ; Smart, RC | 1 |
| Loktionov, A; Martel, N; Popovich, I; Tomatis, L; Yamasaki, H; Zabezhinski, M | 1 |
| Gensler, HL; Welch, K | 1 |
| Conney, AH; Ferraro, T; Huang, MT; Iatropoulos, M; Lou, YR; Reuhl, K; Wang, ZY; Wong, CQ; Yang, CS | 1 |
| Cappel, RE; Gilbert, HF; Kodari, E; Reiners, JJ | 1 |
| Fischer, SM; Haynes, AC; Morris, RJ; Slaga, TJ | 1 |
| Lecuyer, DW; McLean, J; Stuchly, MA | 1 |
| Callary, E; Goddard, M; Lecuyer, DW; McLean, JR; Mitchel, RE; Morrison, D; Schunk, M; Stuchly, MA; Wilkinson, D; Yang, H | 1 |
| Iinuma, F; Negoro, T; Watanabe, M | 2 |
| Matsumoto, T; Nakagawa, S; Takeuchi, M; Takido, M; Yasukawa, K | 1 |
| Aldaz, CM; Bianchi, A; Chen, A; Conti, CJ; DiGiovanni, J; Walker, SB | 1 |
| Bechtel, D; Belury, MA; Fischer, SM; Lee, ML; Leyton, J; Locniskar, M; Slaga, TJ | 1 |
| Aizu, E; Jiang, H; Kato, R; Kiyoto, I; Nakadate, T; Wang, JC; Yamamoto, S | 1 |
| Beltran, L; DiGiovanni, J; Eastin, WC; Naito, M; Walker, SC | 1 |
| Barnett, T; Birt, DF; Dimitroff, K; Pelling, JC; White, LT | 1 |
| Biozzi, G | 1 |
| DiGiovanni, J | 1 |
| Iversen, OH | 4 |
| Byus, CV; Gonzalez, GG | 1 |
| Hirota, M; Irie, R; Jisaka, M; Koshimizu, K; Murakami, A; Ohigashi, H | 1 |
| Chouroulinkov, I; Lasne, C; Nguyen-Ba, G; Oueslatti, R | 1 |
| Skisak, C | 1 |
| Blumenson, LE; East, CJ; Kulesz-Martin, MF; Manly, KF; Siracký, J | 1 |
| Aldaz, CM; Bianchi, AB; Conti, CJ; Navone, NM | 1 |
| Akasu, M; Nakagawa, S; Takeuchi, M; Takido, M; Yasukawa, K | 1 |
| Anisimov, VN; Loktionov, AS; Popovich, IG; Zabezhinskiĭ, MA | 1 |
| Koza, RA; Megosh, LC; O'Brien, TG; Palmieri, M | 1 |
| Baldwin, JK; Cameron, GS; Fischer, SM; Klann, RC; Patrick, KE | 1 |
| Belury, MA; Cumberland, AG; Fischer, SM; Locniskar, M; Patrick, KE | 1 |
| Beecroft, WA; Brandes, LJ; Hogg, GR | 1 |
| de Rey, BM; Durán, HA | 1 |
| Andrews, DF; Collins, SJ; Reddy, AL | 1 |
| Cantu, AR; Pavone, A; Reiners, JJ; Rupp, T | 1 |
| Birt, DF; Bresnick, E; Tye, L; Wei, H | 1 |
| Balaschak, M; Hennings, H; Shores, R; Yuspa, SH | 1 |
| Aizu, E; Kato, R; Nakadate, T; Yamamoto, S | 1 |
| Fujimoto, M; Hirono, I; Ito, K; Matsumoto, K; Tanaka, H | 1 |
| Baker, RS; Steinel, HH | 2 |
| Koch, WH; Kornhauser, A; Lambert, LA; Wamer, WG | 1 |
| Nakagawa, S; Nitta, K; Sato, Y; Takeuchi, M; Takido, M; Yasukawa, K | 1 |
| Fischer, SM; Patamalai, B; Patrick, KE; Slaga, TJ | 1 |
| Gupta, KP; Mehrotra, NK | 3 |
| Bhisey, RA; Veturkar, PL | 1 |
| Hennings, H; Jung, R; Michael, DM; Pettit, GR; Robinson, VA; Yuspa, SH | 1 |
| Glasø, M; Wetteland, P | 1 |
| Bangrazi, C; Biozzi, G; Covelli, V; Doria, G; Mouton, D; Neveu, T; Saran, A | 1 |
| Belman, S; Bosland, MC; Estensen, RD; Savarese, K; Sellakumar, A | 1 |
| Fialkow, PJ; Reddy, AL | 5 |
| Hashiba, H; Hashimoto, Y; Kuroki, T; Nose, K; Tajima, O | 1 |
| Fukuoka, M; Furukawa, F; Hasegawa, R; Hayashi, Y; Imaida, K; Sato, H; Takahashi, M; Takamura, N; Toyoda, K | 1 |
| Dietel, M; Hilz, H; Ludwig, A; Müller, K; Schäfer, G | 1 |
| Binder, RL; Cunniff, JJ; Maurer, JK; Newmann, EA; Sundberg, JP | 1 |
| Hasegawa, T; Iwashima, A; Nishino, A; Nishino, H; Okuyama, T; Shibata, S; Takata, M; Takayasu, J; Tokuda, H; Ueyama, H | 1 |
| Chambers, AF; Craig, AM; Denhardt, DT; Edwards, DR; Guo, XJ; Murphy, LC; Parfett, CL; Reid, RE; Waterhouse, P | 1 |
| Hennings, H; Mitchell, P; Shores, R; Spangler, EF; Yuspa, SH | 1 |
| Christensen, SB; Fujiki, H; Hakii, H; Nakayasu, M; Scheuer, PJ; Suganuma, M; Sugimura, T; Tahira, T | 1 |
| Baird, WM; Carlson, GP; Morse, MA | 1 |
| Cheng, CK; Krieg, TM; Mehrel, T; Roop, DR; Yuspa, SH | 1 |
| Aldaz, CM; Chesner, J; Conti, CJ; Larcher, F; Roop, DR; Slaga, TJ; Trono, D; Whitehead, T | 1 |
| Fischer, SM; Morris, RJ; Slaga, TJ; Tacker, KC | 1 |
| Fitzgerald, DJ; Klann, RC; Piccoli, C; Slaga, TJ; Yamasaki, H | 1 |
| Aldaz, CM; Conti, CJ | 1 |
| Bhisey, RA; Jeyapaul, J | 1 |
| Glasø, M; Hovig, T; Iversen, OH | 1 |
| Birt, DF; Choi, B; Pelling, JC; White, LT | 1 |
| Perchellet, JP; Satyamoorthy, K | 1 |
| Bonfil, RD; Conti, CJ; Klein-Szanto, AJ; Larcher, F | 1 |
| Aldaz, CM; Conti, CJ; Miller, DR; Rotstein, J; Slaga, TJ; Viaje, A | 1 |
| Iwashima, A; Nakagawa, Y; Nishino, H; Takayasu, J; Yamaoka, Y | 1 |
| Cantu, AR; Colby, A; Pavone, A; Reiners, JJ; Rupp, T | 1 |
| DiGiovanni, J; Naito, M | 1 |
| Akhurst, R; Bailleul, B; Balmain, A; Brown, K; Fee, F; Ramsden, M | 1 |
| Miller, DR; Morris, RJ; O'Connell, JF; Patskan, GP; Slaga, TJ; Tacker, K; Viaje, AV | 1 |
| Li, MH; Liu, JG | 1 |
| Amtmann, E; Fürstenberger, G; Marks, F; Sauer, G | 1 |
| Becher, H; Chouroulinkov, I; Day, NE; Lasne, C; Lowy, R; Wahrendorf, J; Yamasaki, H | 1 |
| Fürstenberger, G; Fusenig, NE; Kaina, B; Marks, F; Petrusevska, RT; Schurich, B | 1 |
| Conti, CJ; DiGiovanni, J; Ewing, MW; Phillips, JL; Slaga, TJ | 1 |
| Birt, DF; Pelling, JC; Schweickert, L; Tibbels, MG | 1 |
| Furukawa, F; Hasegawa, R; Hayashi, Y; Imaida, K; Sato, H; Takahashi, M; Toyoda, K | 1 |
| Fuwa, T; Itakura, Y; Iwashima, A; Matsuura, H; Nishino, H | 1 |
| Gill, TJ; Shinozuka, H; Yokota, K | 1 |
| Dlugosz, AA; Dzubow, L; Gilmour, SK; Hietala, O; O'Brien, TG; O'Donnell, K | 1 |
| Eastin, WC | 1 |
| Boutwell, RK | 2 |
| De Luca, LM; Shores, RL; Spangler, EF; Wenk, ML | 1 |
| Athar, M; Bickers, DR; Lloyd, JR; Mukhtar, H | 1 |
| Blumberg, PM; Hennings, H; Sharkey, NA; Yuspa, SH | 1 |
| Anisimov, V; Likhachev, A; Loktionov, A; Napalkov, N; Tomatis, L; Zabezhinski, M | 2 |
| Kim, YS; Park, KK | 1 |
| Hecker, E; Schmidt, R | 1 |
| Fairman, DK; Lewbart, ML; Pashko, LL; Polansky, M; Schwartz, AG | 1 |
| Aizu, E; Hosoda, Y; Kato, R; Kiyoto, I; Nakadate, T; Yamamoto, S | 1 |
| Konoshima, T; Kozuka, M; Tanabe, M; Tokuda, H | 1 |
| Greenhalgh, DA; Harper, JR; Lacal, JC; Reynolds, SH; Strickland, JE; Yuspa, SH | 1 |
| Chiba, M; Klein-Szanto, AJ; Maley, MA | 1 |
| Digiovanni, DM; Fries, JW; Klein-Szanto, AJ; O'Connell, JF; Slaga, TJ | 2 |
| Fujiki, H; Hakii, H; Horiuchi, T; Nakayasu, M; Suganuma, M; Sugimura, T; Takayama, S | 1 |
| Hennings, H; Lichti, U; Michael, D; Yuspa, SH | 1 |
| Kaku, T; Kichikawa, Y; Nakade, O; Ohuchi, T; Okuyama, T; Tateyama, M; Yaegashi, K | 1 |
| Cabral, JR; Galendo, D; Hollstein, M; Martel, N; Tomatis, L; Yamasaki, H | 1 |
| Andringa, A; Baxter, CS; Chalfin, K; Miller, ML | 1 |
| Fujiki, H; Iwashima, A; Konishi, S; Nishino, H; Okabe, H; Okamoto, H; Shibata, S; Sugimura, T; Takizawa, H; Yoshioka, K | 1 |
| Chida, K; Kuroki, T; Munakata, K; Murakami, Y | 1 |
| Graem, N | 1 |
| Hakaim, AG; Jacoby, WT; O'Connell, JF; Weiss, HS | 1 |
| Boutwell, RK; Cleaveland, JS; Ordman, AB; Simsiman, RC | 1 |
| Fujiki, H; Iwashima, A; Kitagawa, K; Nishino, H | 1 |
| Kanno, J; Kasuga, T; Matsubara, O | 2 |
| Bowden, GT; Gensler, HL; Sim, DA | 1 |
| Fürstenberger, G; Kinzel, V; Loehrke, H; Marks, F | 1 |
| Mitina, RL; Morozova, TM | 1 |
| Furukawa, F; Hasegawa, R; Hayashi, Y; Miyakawa, Y; Sato, H; Takahashi, M | 1 |
| Blumenson, L; Kulesz-Martin, M; Lisafeld, B | 1 |
| Gragtmans, NJ; Jevcak, JJ; Mitchel, RE; Morrison, DP | 1 |
| Mehta, RG; Moon, RC | 1 |
| Fujiki, H; Nitta, K; Takeuchi, M | 1 |
| Jacoby, WT; Weiss, HS | 1 |
| Slaga, TJ | 1 |
| Devor, D; Hennings, H; Rehm, S; Ward, JM; Wenk, ML | 1 |
| Anderson, LM; Rice, JM | 2 |
| Caldwell, M; Fialkow, PJ; Reddy, AL | 1 |
| Anisimov, V; Becher, H; Likhachev, A; Loktionov, A; Napalkov, N; Ovsyannikov, A; Tomatis, L; Wahrendorf, J; Zabezhinski, M | 1 |
| Aldaz, CM; Conti, CJ; Klein-Szanto, AJ; Slaga, TJ | 1 |
| Rivenson, A; Tanaka, T | 1 |
| Fujiki, H; Hecker, E; Hirota, M; Horiuchi, T; Suganuma, M; Sugimura, T; Suttajit, M; Wongchai, V; Yoshioka, A | 1 |
| Cohen, SM; Hasegawa, R; St John, M; Tibbels, TS | 1 |
| Conti, CJ; DiGiovanni, J; Kruszewski, FH | 1 |
| Scherneck, S; Wunderlich, V | 1 |
| Fischer, SM; Neades, R; Pelling, JC; Schweickert, L; Strawhecker, J | 1 |
| Bhisey, RA; Borges, A; Veturkar, PL | 1 |
| Gragtmans, NJ; Mitchel, RE; Morrison, DP | 2 |
| Balaschak, M; Greenhalgh, DA; Hennings, H; Koceva-Chyla, A; Restrepo, C; Strickland, JE; Yuspa, SH | 1 |
| Ootsuyama, A; Tanooka, H | 1 |
| Hibasami, H; Maekawa, S; Nakashima, K; Sakurai, M; Tsukada, T | 1 |
| Fujiki, H; Hirota, M; Nakayasu, M; Ojika, M; Suganuma, M; Sugimura, T; Suguri, H; Wakamatsu, K; Yamada, K; Yoshizawa, S | 1 |
| Bower, EA; Kaji, H | 1 |
| Chenicek, KJ; DiGiovanni, J; Naito, M; Naito, Y | 1 |
| Chao, WR; Dawson, MI | 1 |
| Chouroulinkov, I; Grover, P; Lasne, C; Phillips, D | 1 |
| Conney, AH; Huang, MT; Smart, RC; Wong, CQ | 1 |
| Nitta, K; Takeuchi, M; Takido, M; Yasukawa, K | 1 |
| Antony, M; Kumar, S; Mehrotra, NK | 1 |
| Abney, NL; Perchellet, EM; Perchellet, JP | 1 |
| Conti, CJ; DiGiovanni, J; Ewing, MW; Kruszewski, FH; Slaga, TJ | 1 |
| Nakagawa, S; Takeuchi, M; Takido, M; Yasukawa, K | 1 |
| Bowden, GT; Breathnach, R; Finch, J; Krieg, P; Matrisian, L; O'Connell, JF; Ostrowski, LE; Patskan, G; Phillips, J; Slaga, TJ | 1 |
| Burns, PD; Conway, T; Cope, FO; Johnston, D; Murphy, P; Triggs, G; Wagner, FJ; Wille, JJ | 1 |
| Diwan, BA; Henneman, J; Ward, JM; Wenk, ML | 1 |
| Colburn, NH; Diwan, BA; Rice, JM; Spangler, EF; Ward, JM | 1 |
| Klein-Szanto, AJ; Marchok, AC; Terzaghi, M | 1 |
| Roop, DR; Toftgard, R; Yuspa, SH | 1 |
| Hennings, H; Yuspa, SH | 1 |
| Agrawal, HP; Randerath, E; Randerath, K | 1 |
| Hashimura, T; Yoshida, O | 1 |
| Egner, PA; Kensler, TW | 1 |
| Baggiolini, E; Chang, RL; Conney, AH; Huang, MT; Partridge, JJ; Uskokovic, M; Wood, AW | 1 |
| Fürstenberger, G; Kinzel, V; Marks, F; Schwarz, M | 1 |
| Boutwell, RK; Cleaveland, JS; Ordman, AB | 1 |
| Arranto, A; Stenbäck, F | 1 |
| Fujita, J; Sugawara, K; Tokuda, H; Yoshida, O | 1 |
| Adolf, W; Hecker, E; Hergenhahn, M; Schmidt, R; Sorg, B | 1 |
| Reyes-Mayes, D; Volm, M; Wayss, K | 1 |
| Cake, M; Godfrey, M; Toia, R; Yeoh, G | 1 |
| Boutwell, RK; Perchellet, JP | 1 |
| Klein-Szanto, AJ; Nelson, KG; Shah, Y; Slaga, TJ | 1 |
| Bhide, SV; Munir, KM; Rao, KV | 1 |
| Morita, T; Moroyama, T; Okamoto, T; Okuda, K; Takada, K; Yoshiga, K | 1 |
| Pashko, LL; Rovito, RJ; Schwartz, AG; Sobel, EL; Williams, JR | 1 |
| Benditt, EP; Bond, JA; Gown, AM; Juchau, MR; Yang, HL | 1 |
| Benfield, JR; Cohen, AH; Fu, PC; Hammond, WG; Jensen, T; Pak, HY; Paladugu, RR; Shors, EC; Teplitz, RL | 1 |
| Boutwell, RK; Conrad, EA; Verma, AK | 2 |
| Albert, RE; Burns, FJ | 1 |
| Mastro, AM | 1 |
| Lesca, P | 1 |
| Nesnow, S; Reiners, JJ; Slaga, TJ | 1 |
| DiPaolo, JA; Evans, CH; Greiner, JW | 1 |
| Argyris, TS | 4 |
| Klein-Szanto, A; Nettesheim, P; Terzaghi, M | 1 |
| Bernfeld, P; Homburger, F | 1 |
| Ashendel, CL; Boutwell, RK; Garcia, CT; Verma, AK | 1 |
| Dederer, E; Goerttler, K; Hesse, B; Loehrke, H; Rosenkranz, G; Schweizer, J | 1 |
| Albert, RE; Burns, FJ; Morris, EP | 1 |
| Pai, SB; Steele, VE; Topping, DC | 1 |
| Hecker, E; Pyerin, WG | 1 |
| Habs, M; Schmähl, D; Wagner, G | 1 |
| Astrup, EG; Iversen, OH | 1 |
| Bartolini, G; Fujiki, H; Hakii, H; Moore, RE; Suganuma, M; Sugimura, T; Takayama, S | 1 |
| Fürstenberger, G; Goerttler, K; Kinzel, V; Loehrke, H; Marks, F | 1 |
| Decina, PC; Diamond, L; DiGiovanni, J; Prichett, WP | 1 |
| Hayashi, Y; Imazawa, T; Kurokawa, Y; Matsushima, Y; Takamura, N | 1 |
| Barrett, JC; Gray, TE; Mass, MJ; Nettesheim, P; Steele, VE | 1 |
| Fürstenberger, G; Marks, F | 1 |
| Fürstenberger, G; Goerttler, K; Kinzel, V; Loehrke, H; Marks, F; Richards, J | 1 |
| Curtis, GL; Heidrick, ML; Ryan, WL; Stenback, F | 1 |
| Fischer, SM; Klein-Szanto, AJ; Major, S; Nelson, K; Slaga, TJ; Weeks, CE | 1 |
| Fischer, SM; Gleason, GL; Nelson, K; Slaga, TJ | 1 |
| Nettesheim, P; Topping, DC | 1 |
| Boger, E; Moolten, FL; Rizzone, A; Schreiber, B; Weiss, AJ | 1 |
| Enaka, K; Ono, T; Umeda, M | 1 |
| Boutwell, RK; Verma, AK | 2 |
| Peto, R; Shubik, P; Stenbäck, F | 3 |
| Morgan, DL; Yuspa, SH | 1 |
| Klein-Szanto, AJ; Slaga, TJ; Triplett, LL; Trosko, KE; Yotti, LP | 1 |
| Goerttler, K; Hesse, B; Loehrke, H; Milz, A; Schweizer, J | 1 |
| Donahoe, R; Ferguson, E; Geusz, S; Hennings, H; Spangler, EF; Wenk, M; Yuspa, SH | 1 |
| Kitamura, Y; Sonoda, T; Tanooka, H; Tsuyama, K | 1 |
| Ashendel, CL; Astrup, E; Boutwell, RK; Verma, AK | 1 |
| Verma, AK | 1 |
| Komitowski, D | 1 |
| Barrett, JC; Gray, T; Sisskin, EE | 1 |
| Buhler, DR; Chang, RL; Conney, AH; Jerina, DM; Levin, W; Newman, MS; O'Malley, RF; Slaga, TJ; Wood, AW | 1 |
| Goerttler, K; Hecker, E; Hesse, B; Loehrke, H; Schweitzer, J; Seip, H | 1 |
| Bolmer, SD; Wolf, G | 1 |
| Fujiki, H; Matsukura, N; Suganuma, M; Sugimura, T; Takayama, S | 1 |
| Akihisa, T; Motohashi, S; Takido, M; Tamura, T; Tokutake, N; Yasukawa, K | 1 |
| Jenkinson, HF; McMillan, MD; Shearer, BH | 1 |
| Abhyankar, S; Greenhalgh, DA; Hennings, H; Ngai, P; Schweizer, J; Strickland, JE; Sutter, C; Ueda, M; Yuspa, SH | 1 |
| Celli, G; Darwiche, N; De Luca, LM; Glick, AB; Tennenbaum, T; Yuspa, SH | 1 |
| Konoshima, T; Kozuka, M; Takasaki, M; Tokuda, H | 2 |
| Kim, TW; Smart, RC | 1 |
| Frenkel, K; Wei, H; Wei, L | 1 |
| Chada, K; Conney, AH; D'Armiento, J; Dalal, SS; DiColandrea, T; Huang, MT; Okada, Y | 1 |
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| Gurley, KE; Kemp, CJ; Philipp, J; Seidel, K; Vo, K | 1 |
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| Biozzi, G; Bouthillier, Y; Covelli, V; Doria, G; Mouton, D; Pazzaglia, S; Pioli, C; Rebessi, S; Saran, A | 1 |
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| Biozzi, G; Covelli, V; Doria, G; Mouton, D; Neveu, T; Pazzaglia, S; Rebessi, S; Saran, A | 1 |
| Ishihara, N; Mori, H; Nakamura, Y; Nishidai, S; Ohigashi, H; Torikai, K; Yamamoto, M | 1 |
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| Enoki, T; Kato, I; Ohnogi, H; Sagawa, H; Takashima, F; Tominaga, T | 1 |
| Chang, YH; Chen, WJ; Ho, CT; Lai, CS; Pan, MH; Tsai, ML | 1 |
| Kominami, R; Mao, JH; Miura, I; Miyasaka, Y; Okumura, K; Saito, M; Sato, M; Wakabayashi, Y; Wakana, S | 1 |
| Hayward, R; Lo, RS; Marais, R; Martin, M; Niculescu-Duvaz, D; Sanchez-Laorden, B; Springer, C; Viros, A; Yashar, S; Yu, CC; Zambon, A | 1 |
| Clarke, M; Das, S; Huels, D; Jamieson, T; Jung, A; Neumann, J; Nibbs, RJ; Olson, MF; Samuel, MS; Sansom, OJ; Steele, CW | 1 |
| Bonsignore, L; Drexler, SK; Gross, O; Hermeking, H; Jackstadt, R; Masin, M; Schneider, P; Tardivel, A; Tschopp, J; Yazdi, AS | 1 |
| Belloli, S; Beltrami, E; Fassina, A; Fazio, F; Giorgio, M; Marcu, R; Moresco, R; Pelicci, P; Valtorta, S | 1 |
| Chen, HD; He, CD; Liu, CH; Lu, T; Ma, GZ; Qiao, J; Wei, B; Wei, HC | 1 |
| Braeuning, A; Münzel, PA; Schwarz, M | 1 |
| Cheng, KH; Chiou, YS; Ho, CT; Pan, MH; Sang, S; Wang, YJ | 1 |
| Ishibashi, T; Maoka, T; Ohmori, A; Osawa, A; Shindo, K; Suzuki, N; Tokuda, H; Yasui, H | 1 |
| Arimoto-Kobayashi, S; Kamiya, T; Negishi, T; Okamoto, G; Yuhara, Y; Zhang, X | 1 |
| Furukawa, F; Kawabe, M; Numano, T; Suguro, M; Taguchi, F; Tsutsumi, H; Urano, K | 1 |
| Amaral, L; Engi, H; Hamilton, G; Hohmann, J; Maoka, T; Molnar, J; Mucsi, I; Olszewski, U; Suzuiki, N; Tokuda, H; Vasas, A | 1 |
| Cescon, D; Chio, II; Dominguez-Brauer, C; Elia, AJ; Ghazarian, D; Gorrini, C; Haight, J; Hao, Z; Harris, IS; Inoue, S; Itsumi, M; Li, WY; Mak, TW; McCracken, S; Melino, G; Penn, LJ; Sasaki, M; Silvester, J; Snow, B; Ueda, T; Wakeham, A; Yamamoto, K; You-Ten, A; Zhou, L | 1 |
| Hong, JI; Jung, BG; Kim, TH; Ko, JH; Lee, BJ; Lee, JA; Park, YS | 1 |
| Hanausek, M; Junco, JJ; Kowalczyk, MC; Kowalczyk, P; Slaga, TJ; Tolstykh, O; Walaszek, Z | 1 |
| Nakae, D; Nakajima, J; Yasukawa, K | 1 |
| Ichiishi, E; Iida, A; Kapadia, GJ; Konoshima, T; Rao, GS; Sridhar, R; Suzuki, N; Takasaki, M; Tokuda, H | 1 |
| Avivi, A; Band, M; Hirsh, M; Iancu, TC; Malik, A; Manov, I; Shams, I; Sotnichenko, N | 1 |
| Belai, EB; Campanelli, AP; Cavassani, KA; de Oliveira, CE; Garlet, GP; Gasparoto, TH; Ramos, RN; Silva, JS; Torres, SA | 1 |
| Fujiwara, K; Ghosh, S; Liang, P; Morien, E; Nagase, H; Soma, M | 1 |
| Antsiferova, M; Feyerabend, TB; Förster, A; Hartmann, K; Hohl, D; Huber, M; Martin, C; Rodewald, HR; Werner, S | 1 |
| Chen, X; Fagin, JA; Johnson, LK; Knauf, JA; Makarewicz, JM | 1 |
| Ali, F; Khan, AQ; Khan, R; Lateef, MA; Maqbool, T; Sultana, S | 1 |
| Baban, B; Chandler, P; DuHadaway, JB; Keough, MP; Mandik-Nayak, L; Mellor, AL; Merlo, LM; Metz, R; Muller, AJ; Pigott, E; Prendergast, GC; Rust, S; Smith, C | 1 |
| Blankenstein, T; Bozrova, SV; Chashchina, AA; Drutskaya, MS; Kammertoens, T; Nedospasov, SA; Qin, Z; Quarcoo, D; Rothe, M | 1 |
| Hogg, N; McNeill, E | 1 |
| Maurer, M; Metz, M; Siebenhaar, F | 1 |
| Chawsheen, HA; Colburn, NH; Gerard, M; Jiang, H; Mishra, M; Toledano, MB; Wei, Q; Wu, L; Young, MR | 1 |
| Christiansen, H; Dittmann, K; Frommhold, A; Hahn, H; Heß, I; König, S; Lühder, F; Nitzki, F; Reifenberger, J; Schulz-Schaeffer, W; Uhmann, A; Zabel, S | 1 |
| Chen, W; Fan, F; Liu, Y; Liu, Z; Lu, Y; Pei, C; Ruan, J; Shan, Y; Shen, C; Tao, L; Tian, C; Wang, A; Wang, S; Wu, H; Zheng, S; Zhou, L | 1 |
| Guo, S; He, X; Lan, H; Lan, T; Li, J; Li, W; Qi, C; Wang, L; Wei, P; Yang, Y; Ye, J; Zhang, Q | 1 |
| Cipolat, S; Hoste, E; Natsuga, K; Quist, SR; Watt, FM | 1 |
| Argade, A; Chatterjee, A; Deshpande, SS; Jain, MR; Mohapatra, J; Shah, GB; Sharma, M | 1 |
| Cha, IH; Cho, SB; Choi, EJ; Kim, J; Kim, KY; Zhang, X; Zheng, Z; Zhu, L | 1 |
| Aoto, Y; Goitsuka, R; Hachiya, T; Hirose, S; Isogai, E; Katsuragi, Y; Kominami, R; Nakamura, T; Okumura, K; Saito, M; Sakakibara, Y; Wakabayashi, Y | 1 |
| García-Fernández, RA; García-Iglesias, MJ; Pérez-Martínez, C | 1 |
| Catapang, A; Dennis, EA; Dumlao, DS; Fischer, SM; Herschman, HR; Ishikawa, TO; Jiao, J; Magyar, CE; Mikulec, C; Norris, PC | 1 |
| Hart, RP; Huang, MT; Huang, Y; Kong, AN; Lee, JH; Lu, Y; Pung, D; Ramirez, C; Shu, L; Su, ZY; Verzi, M; Yang, AY; Zhang, C | 1 |
| Asano, R; Iizuka, H; Nakae, Y; Nakajima, S; Ogasawara, K; Sakata, I; Takahashi, H | 1 |
| Becker, JC; Zur Hausen, A | 1 |
| Aggarwal, V; Monga, J; Nongalleima, K; Sharma, M; Suthar, SK | 1 |
| Bryant, CJ; Caddye, E; Caunt, CJ; Davidson, J; Delavaine, L; East, P; Keyse, SM; Kidger, AM; Rushworth, LK; Stewart, G; van Schelven, S | 1 |
| Bernabéu, C; del Castillo, G; Langa, C; Martín-Villar, E; Pérez-Gómez, E; Quintanilla, M; Renart, J; Sánchez-Blanco, E; Valbuena-Diez, AC | 1 |
| Naseem, I; Salman, M | 1 |
| Amberg, N; Glitzner, E; Holcmann, M; Novoszel, P; Sibilia, M; Stulnig, G | 1 |
| Dean, DC; Kasetti, RB; Li, Q; Lu, Q; Sambandam, SAT; Xue, L | 1 |
| Fuchs, E; Oristian, D; Oshimori, N | 1 |
| Carr, TD; Feehan, RP; Hall, MN; Rüegg, MA; Shantz, LM | 1 |
| Athar, M; Cochran, JB; Elmets, CA; McKay, KM; Nasti, TH; Timares, L; Tsuruta, Y; Yusuf, N | 1 |
| Chen, C; Fan, F; Lin, C; Liu, Y; Liu, Z; Lu, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zhao, L; Zhu, P; Zhu, Z | 1 |
| Hall, RP; He, Y; Huang, Q; Kato, TA; Li, CY; Li, F; Liu, X | 1 |
| Brady, M; Brennan-Crispi, DM; Hossain, C; Mahoney, MG; Riobo, NA; Sahu, J | 1 |
| Cao, Y; Chen, C; Fan, F; Lin, C; Liu, Z; Lu, Y; Shan, Y; Shen, C; Sun, L; Tao, Y; Wang, A; Wang, S; Wei, Z; Wu, H; Zheng, S; Zhu, P | 1 |
| DiGiovanni, J; Rho, O; Srivastava, J; Youssef, RM | 1 |
| Järvinen, TA; Laitinen, AM; May, U; Nieminen, K; Prince, S; Uusitalo-Järvinen, H; Vähätupa, M | 1 |
| Bao, R; Bechill, J; Bindokas, VP; Faber, PW; Lingen, MW; Spiotto, MT; Zhong, R | 1 |
| Beck, A; Fletcher, S; Goldstein, J; Horsley, V; Lin, S; Roberts, N; Roth, E; Suárez-Fariñas, M; Tadeu, A; Wu, C; Zeiss, C; Zwick, R | 1 |
| Bauer, SJ; Havighurst, TC; Kim, K; Singh, A; Verma, AK; Wheeler, DL | 1 |
| Abdul Hamid, R; Khaza'ai, H; Mohtarrudin, N; Saiful Yazan, L; Yeong, LT | 1 |
| Hermeking, H; Lodygin, D; Verdoodt, B; Winter, M | 1 |
| Garg, ML; Koul, A; Mohanty, BP; Sati, J | 1 |
| Baderca, F; Borcan, F; Coricovac, D; Danciu, C; Dehelean, CA; Pavel, I; Pinzaru, I; Soica, C; Spandidos, DA; Tsatsakis, AM | 1 |
| Hu, YQ; Wang, J; Wu, JH | 1 |
| Alitalo, K; Harjunen, V; Heljasvaara, R; Holopainen, T; Honkanen, HK; Izzi, V; Petäistö, T; Pihlajaniemi, T | 1 |
| Balmain, A; Del Rosario, R; Ginzinger, D; Halliwill, KD; Kang, HC; Quigley, DA | 1 |
| Berx, G; Declercq, W; Denecker, G; Devos, M; Gilbert, B; Haigh, J; Hochepied, T; Lambert, J; Lemeire, K; Leurs, K; Libbrecht, L; Lippens, S; Mc Guire, C; Van Den Broecke, C; Vandenabeele, P; Vuylsteke, M | 1 |
| Asai, M; Asai, N; Enomoto, A; Kato, T; Mii, S; Murakumo, Y; Nagino, M; Shiraki, Y; Sunagawa, M; Takahashi, M | 1 |
| Bodman-Smith, K; Boukamp, P; Daher, CF; El-Sibai, M; Mroueh, MA; Shebaby, WN; Taleb, RI | 1 |
| Callejas-Valera, JL; Cimas, FJ; Fernandez-Aroca, DM; Garcia-Gil, E; García-Olmo, DC; Gutkind, JS; Hernández-Losa, J; Marcos, P; Melgar-Rojas, P; Ortega-Muelas, M; Pascual-Serra, R; Ramón Y Cajal, S; Roche, O; Ruiz-Hidalgo, MJ; Sanchez-Prieto, R | 1 |
| Chugh, NA; Kaur, N; Koul, A | 1 |
| Christensen, R; Füchtbauer, AC; Füchtbauer, EM; Gunnarsson, A; Jensen, UB; Owens, DM; Ramsing, M | 1 |
| Anguish, LJ; Coonrod, SA; Horibata, S; McElwee, JL; McLean, D; Mohanan, S; Mukai, C; Sams, K; Yan, A | 1 |
| Hamid, RA; Md Roduan, MR; Mohtarrudin, N; Sulaiman, H | 1 |
| Patial, V; Sharma, S; Sk, UH | 1 |
| Liu, P; Wang, D | 1 |
| Faustino-Rocha, AI; Ferreira, L; Ferreira, R; Gama, A; Neuparth, MJ; Oliveira, PA; Rodrigues, D; Vitorino, R | 1 |
| Ahn, JS; Cha-Molstad, H; Choi, TW; Han, HJ; Hong, JT; Hwang, J; Kim, BY; Kim, HJ; Kwon, YT; Lee, HG; Lee, KH; Lee, Y; Mun, J; Soung, NK | 1 |
| Kong, YH; Xu, SP | 1 |
| Balmain, A; Del Rosario, R; Harris, S; Kandyba, E; Reeves, MQ | 1 |
| Balaiya, V; Johnson, LK; Koster, MI; Lakshmanachetty, S | 1 |
| Hall, JR; House, JS; Jima, DD; Messenger, ZJ; Smart, RC; Tam, HW; Tokarz, DA | 1 |
| Asfaha, S; Boland, K; Gordon, D; Jin, G; Johnson, K; Lad, S; Londono, D; Morris, RJ; Park, H; Patterson, KS; Readio, N; Singh, A; Trempus, C; Wang, TC; Yang, X | 1 |
| Banu, N; Bilal, N; Hasan, S; Suhail, N | 1 |
| Gubareva, EA; Maidin, MA; Panchenko, AV; Tyndyk, ML; Vinogradova, LA | 1 |
| Al Habeeb, A; Bai, X; Cho, HR; Liu, M; Lu, C; Post, A; Wang, Y; Xiang, YY | 1 |
| Abd Hamid, R; Md Roduan, MR; Mohtarrudin, N | 1 |
| Järvinen, TAH; Junttila, I; Pemmari, T; Pesu, M; Vähätupa, M | 1 |
| Cai, H; Hua, Z; Huang, H; Shi, J; Wei, Y; Zhang, L | 1 |
| Furukawa, F; Ishida, Y; Kimura, A; Kondo, T; Kuninaka, Y; Mukaida, N; Nosaka, M; Yamamoto, Y | 1 |
| Hu, X; Wang, L; Zhang, L; Zhang, T | 1 |
| Kreft, M; Krotenberg Garcia, A; Ramovs, V; Sonnenberg, A | 1 |
| Al Matouq, J; Bloom, C; Hansen, LA; Holmes, M; Holmes, TR; Lovas, S; Madson, JG; Nicola, L; Palermo, NY; Rudd, JC; Sioda, N | 1 |
| Athar, M; Elmets, CA; Nasti, TH; Sherwani, MA; Timares, L; Yusuf, N | 1 |
| Chiou, YS; Chou, PY; Ho, CT; Lee, PS; Nagabhushanam, K; Pan, MH | 1 |
| Brakebusch, C; Li, H | 1 |
| Aida, E; Hara, S; Kamei, D; Kuwata, H; Nakatani, Y; Ochiai, T; Sasaki, Y | 1 |
| Bajpai, D; Brooks, SR; Cataisson, C; Hasneen, K; Inoue, Y; Kellett, M; Mehdizadeh, S; Morasso, MI; Motegi, SI; Overmiller, A; Palazzo, E; Sawaya, A; Uchiyama, A; Yuspa, SH | 1 |
| Aird, KM; Buj, R; Chen, CW; Dahl, ES; Hobbs, RP; Imamura-Kawasawa, Y; Kossenkov, AV; Leon, KE; Lesko, E; Tangudu, NK | 1 |
| González-Rodríguez, M; Hiihtola, L; Järvinen, TAH; Junttila, IS; Kummola, L; Määttä, J; Parviainen, L; Pemmari, T; Salomaa, T; Salonen, N; Vähätupa, M | 1 |
| Dang, Y; Guo, C; Li, Y; Liang, Y; Liu, M; Shi, Y; Wang, C; Xiang, W; Xu, P; Ye, X; Zhang, X | 1 |
| Ghadi, DS; Joshi, P; Waghmare, SK | 1 |
24 review(s) available for tetradecanoylphorbol acetate and 9,10-dimethyl-1,2-benzanthracene
| Article | Year |
|---|---|
The hamster cheek pouch model of carcinogenesis and chemoprevention.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Cheek; Cocarcinogenesis; Cricetinae; Hyperplasia; Keratins; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Precancerous Conditions; Tetradecanoylphorbol Acetate | 1992 |
Studies and perspectives of signal transduction in the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Communication; Humans; Keratinocytes; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Interaction and distinction of genotoxic and non-genotoxic events in carcinogenesis.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Humans; Mice; Mutagens; Neoplasms; Risk Factors; Tetradecanoylphorbol Acetate | 1992 |
Natural history of intraepithelial neoplasia in humans with implications for cancer chemoprevention strategy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinoma; Epithelium; Humans; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Differential gene expression during tumor promotion and progression in the mouse skin model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA; Gene Expression Regulation, Neoplastic; Matrix Metalloproteinase 3; Metalloendopeptidases; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms, Multiple Primary; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitins | 1991 |
Modification of multistage skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cocarcinogenesis; Disease Models, Animal; Mice; Precancerous Conditions; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1991 |
The premalignant nature of mouse skin papillomas: histopathologic, cytogenetic, and biochemical evidence.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Chromosome Aberrations; Chromosome Disorders; Karyotyping; Keratins; Mice; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Genetic background and development of skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cricetinae; Disease Susceptibility; Guinea Pigs; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Phorbol Esters; Rats; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1989 |
Development of murine skin neoplasia studied with enzymes used as cell markers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinoma; Fibrosarcoma; Mice; Papilloma; Phosphoglycerate Kinase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
The action of oncogenes and growth factors in tumour initiation and promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Gene Expression Regulation; Genes, ras; Methylnitronitrosoguanidine; Mice; Mutation; Oncogenes; Restriction Mapping; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factors | 1989 |
Investigations of multistage carcinogenesis: applications of in vitro-in vivo studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Methylnitronitrosoguanidine; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
SENCAR mouse skin tumorigenesis model versus other strains and stocks of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Disease Models, Animal; Drug Evaluation, Preclinical; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1986 |
Phorbol ester tumor promoters and lymphocyte proliferation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Lymphocyte Activation; Lymphocytes; Mice; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1983 |
The paradigm of two-stage carcinogenesis: a critical attitude.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Interactions; Hyperplasia; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Nude; Models, Biological; Neoplasms; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Urethane | 1984 |
Mouse skin: a useful model system for studying the mechanism of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkylating Agents; Animals; Carcinogens; Cell Communication; Cell Differentiation; Cell Division; Cocarcinogenesis; DNA; Indomethacin; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Polyamines; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Transgenic approaches to the analysis of ras and p53 function in multistage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Genes, p53; Genes, ras; Mice; Mice, Transgenic; Mutation; Neoplasms, Radiation-Induced; Oncogenes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Effect of conjugated linoleic acid on carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimutagenic Agents; Cell Transformation, Neoplastic; Female; Gastrointestinal Neoplasms; Linoleic Acids; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred ICR; Rats; Rats, Inbred F344; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Green tea and skin--anticarcinogenic effects.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Dermatitis; Humans; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1994 |
Histopathology of human intraepithelial neoplasia with implications for chemoprevention strategy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Anticarcinogenic Agents; Epithelium; Female; Humans; Mice; Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate; Uterine Cervical Neoplasms | 1993 |
Upregulation of E2F transcription factors in chemically induced mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carrier Proteins; Cell Cycle Proteins; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; E2F3 Transcription Factor; E2F4 Transcription Factor; E2F5 Transcription Factor; Female; Mice; Papilloma; Retinoblastoma-Binding Protein 1; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor DP1; Transcription Factors; Up-Regulation | 1999 |
Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Brassica; Carcinogens; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Isothiocyanates; Mice; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Skin; Skin Neoplasms; Sulfoxides; Tetradecanoylphorbol Acetate; Thiocyanates; Time Factors | 2006 |
Skin cancer chemoprevention by α-santalol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Drugs, Chinese Herbal; Humans; Mice; Mice, Mutant Strains; Phytotherapy; Plant Oils; Polycyclic Sesquiterpenes; Santalum; Sesquiterpenes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Animal models of melanoma: a somatic cell gene delivery mouse model allows rapid evaluation of genes implicated in human melanoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Avian Leukosis Virus; Avian Proteins; Cell Line, Tumor; Disease Models, Animal; Gene Transfer Techniques; Genetic Vectors; Humans; Melanocytes; Melanoma; Melanoma, Experimental; Mice; Mice, Transgenic; Neoplasm Transplantation; Receptors, Virus; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2011 |
Non-melanoma skin cancer in mouse and man.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Genes, p53; Genes, ras; Humans; Melanoma; Mice; Mutation; Neoplasm Invasiveness; Neoplastic Stem Cells; Papilloma; Risk Assessment; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 2013 |
846 other study(ies) available for tetradecanoylphorbol acetate and 9,10-dimethyl-1,2-benzanthracene
| Article | Year |
|---|---|
Inflammatory, tumor initiating and promoting activities of polycyclic aromatic hydrocarbons and diterpene esters in mouse skin as compared with their prostaglandin releasing potency in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diterpenes; Dose-Response Relationship, Drug; In Vitro Techniques; Inflammation; Macrophages; Mice; Polycyclic Compounds; Precancerous Conditions; Prostaglandins E; Skin; Tetradecanoylphorbol Acetate; Time Factors | 1978 |
Two-stage (initiation-promotion) carcinogenesis in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Croton Oil; Female; In Vitro Techniques; Mice; Models, Biological; Neoplasms, Experimental; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1978 |
Transmaternal modification of the Berenblum/Mottram experiment in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Fetus; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1978 |
Effects of the tumor-promoting agent 12-O-tetradecanoylphorbol-13-acetate on normal and "preneoplastic" mouse submandibular gland epithelial cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Division; Cells, Cultured; Dimethyl Sulfoxide; Epithelium; Phorbols; Submandibular Gland; Tetradecanoylphorbol Acetate | 1979 |
Systemic two-stage carcinogenesis in the epithelium of the forestomach of mice using 7,12-dimethylbenz(a)anthracene as initiator and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Drug Synergism; Epithelium; Female; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phorbols; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Potent tumor-initiating activity of the 3,4-dihydrodiol of 7,12-dimethylbenz(a)anthracene in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Effects of structural changes on the tumor-promoting activity of phorbol myristate acetate on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldehydes; Animals; Carcinoma, Squamous Cell; Decanoates; Drug Synergism; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Phenotypic properties and tumor promotor-induced alterations in rat embryo cells transformed by adenovirus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoviruses, Human; Animals; Benzopyrenes; Cell Aggregation; Cell Division; Cell Transformation, Neoplastic; Cell Transformation, Viral; Clone Cells; Cocarcinogenesis; Concanavalin A; Embryo, Mammalian; Membrane Proteins; Phenotype; Phorbols; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate | 1979 |
Inhibition of phorbol ester-induced tumor promotion in mice by vitamin A analog and anti-inflammatory steroid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Drug Synergism; Female; Fluocinolone Acetonide; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin A | 1979 |
Life history and histopathology of ultraviolet light-induced skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Cricetinae; Female; Mice; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Papilloma; Rats; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1978 |
Dynamics of neoplastic development in carcinogen-exposed tracheal mucosa.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Adhesion; Cells, Cultured; Epithelium; Female; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Tracheal Neoplasms; Transplantation, Isogeneic | 1979 |
The initiation of tumours on mouse skin by dihydrodiols derived from 7,12-dimethylbenz(a)anthracene and 3-methylcholanthrene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benz(a)Anthracenes; Chemical Phenomena; Chemistry; Female; Methylcholanthrene; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
[Skin transplantation in the study of chemical carcinogenesis. III. Reduced papilloma-formation after initiation during epidermal hyperplasia induced by skin grafting or by a single application of the cocarcinogen TPA].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hyperplasia; Mice; Mice, Inbred C3H; Papilloma; Skin; Skin Transplantation; Tetradecanoylphorbol Acetate; Time Factors; Transplantation, Autologous | 1975 |
Phorbol as a possible systemic promoting agent for skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Synergism; Female; Injections, Intraperitoneal; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Diaplacental carcinogenesis: tumor localization and tumor incidence in NMRI mice after diaplacental initiation with DMBA and urethane and postnatal promotion and the phorbol ester TPA in a modified 2-stage Berenblum/Mottram experiment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abortion, Spontaneous; Administration, Oral; Administration, Topical; Animals; Benz(a)Anthracenes; Female; Genital Neoplasms, Female; Injections, Intraperitoneal; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Neoplasms, Multiple Primary; Organ Specificity; Phorbols; Pregnancy; Tetradecanoylphorbol Acetate; Urethane | 1977 |
Tumor persistence and regression in skin carcinogenesis. An experimental study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Female; Mice; Neoplasm Regression, Spontaneous; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1978 |
Studies with chlorinated dibenzo-p-dioxins, polybrominated biphenyls, and polychlorinated biphenyls in a two-stage system of mouse skin tumorigenesis: potent anticarcinogenic effects.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Dioxins; Drug Interactions; Enzyme Induction; Female; Hydrocarbons, Chlorinated; Mice; Neoplasms, Experimental; Polybrominated Biphenyls; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Epidermal ribosome accumulation during two-stage skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Membranes; Mice; Neoplasms, Experimental; Precancerous Conditions; Ribosomes; RNA, Neoplasm; RNA, Ribosomal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1977 |
Induction of the formation of new hair follicles in mouse tail epidermis by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hair; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tail; Tetradecanoylphorbol Acetate | 1977 |
Epidermal intercellular relationships during carcinogenesis and cocarcinogenesis as revealed by scanning electron microscopy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Cell Transformation, Neoplastic; Cocarcinogenesis; Epithelium; Extracellular Space; Female; Hyperplasia; Intercellular Junctions; Mice; Microscopy, Electron, Scanning; Skin; Tetradecanoylphorbol Acetate | 1977 |
Development of a system for controlled release of benzo(a)pyrene, 7,12-dimethylbenz(a)anthracene, and phorbol ester for tumor induction in heterotopic tracheal grafts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bees; Benz(a)Anthracenes; Benzopyrenes; Carbon; Delayed-Action Preparations; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred F344; Solubility; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms; Transplantation, Isogeneic; Waxes | 1978 |
Inhibition of two-stage carcinogenesis in mouse skin with bis(2-chloroethyl)sulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred ICR; Mustard Compounds; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Sulfides; Tetradecanoylphorbol Acetate | 1976 |
Regression kinetics of mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antilymphocyte Serum; Dose-Response Relationship, Drug; Female; Half-Life; Mice; Neoplasm Regression, Spontaneous; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Two-stage chemical oncogenesis in cultures of C3H/10T1/2 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzopyrenes; Cell Transformation, Neoplastic; Cells, Cultured; Drug Administration Schedule; Methylcholanthrene; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1976 |
Measurement and significance of subclinical effects of chemicals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allergens; Animals; Carbon Monoxide Poisoning; Carboxyhemoglobin; Drug Synergism; Environmental Exposure; Environmental Pollutants; Humans; Mice; Neoplasms, Experimental; Paralysis; Tetradecanoylphorbol Acetate; Tritolyl Phosphates | 1976 |
Epidermal cell proliferation and promoting ability of phorbol esters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Edema; Female; Hyperplasia; Inflammation; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Diaplacental carcinogenesis: initiation with the carcinogens dimethylbenzanthracene (DMBA) and urethane during fetal life and postnatal promotion with the phorbol ester TPA in a modified 2-stage Berenblum/Mottram experiment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Drug Synergism; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Phorbols; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1976 |
Improved tumour yields by means of a TPA-DMBA-TPA variation of the Berenrlum-Mottram experiment on the back skin of NMRI mice. The effect of stationary hyperplasia without inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Anti-tumor-promoting activities of afromosin and soyasaponin I isolated from Wistaria brachybotrys.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cocarcinogenesis; Female; Isoflavones; Lung Neoplasms; Mice; Mice, Inbred ICR; Oleanolic Acid; Plants, Medicinal; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Correlation between chemical suppression of natural killer cell activity in mice and susceptibility to cytomegalovirus: rationale for applying murine cytomegalovirus as a host resistance model and for interpreting immunotoxicity testing in terms of risk o
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cadmium; Cadmium Chloride; Cells, Cultured; Chlorides; Cyclophosphamide; Cyclosporine; Cytomegalovirus Infections; Disease Susceptibility; Female; G(M1) Ganglioside; Immunity, Cellular; Immunosuppressive Agents; Killer Cells, Natural; Mice; Mice, Inbred C3H; Nickel; Polychlorinated Dibenzodioxins; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate | 1992 |
Dissociation of sensitivities to tumor promotion and progression in outbred and inbred SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinoma, Squamous Cell; Female; Genes, ras; Keratins; Methylnitronitrosoguanidine; Mice; Mutation; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1992 |
Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Carcinoma, Squamous Cell; Electrophoresis, Polyacrylamide Gel; Epithelium; Female; Fluorescent Antibody Technique; Gene Expression; Genes, ras; Immunoenzyme Techniques; Keratins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mutation; Papilloma; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Immunogenetic influences on the initiation stage of the cutaneous chemical carcinogenesis pathway.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Disease Susceptibility; DNA; DNA Adducts; Enzyme Induction; Female; Mice; Mice, Inbred C3H; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Potent preventive action of alpha-carotene against carcinogenesis: spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by alpha-carotene than by beta-carotene.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; beta Carotene; Carotenoids; Drug Screening Assays, Antitumor; Humans; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate | 1992 |
Inhibitory effect of green tea on the growth of established skin papillomas in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catechin; Drug Screening Assays, Antitumor; Female; Flavonoids; Injections, Intraperitoneal; Mice; Papilloma; Phenols; Plant Extracts; Polymers; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1992 |
Inhibition of mouse skin tumorigenesis by dexamethasone occurs through a Ha-ras-independent mechanism.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenalectomy; Animals; Blotting, Northern; Dexamethasone; Female; Genes, ras; Mice; Papilloma; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Identification and quantification of a carcinogen-induced molecular initiation event in cell transformation.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Gene Expression; Genes, ras; Mice; Molecular Sequence Data; Mutation; Tetradecanoylphorbol Acetate | 1992 |
Dietary retinoids are essential for skin papilloma formation induced by either the two-stage or the complete tumorigenesis model in female SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Diet; Diterpenes; Female; Mice; Mice, Inbred Strains; Papilloma; Retinyl Esters; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Vitamin A; Vitamin A Deficiency | 1992 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-caused tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated SENCAR mouse skin by a polyphenolic fraction isolated from green tea.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Female; Lipoxygenase; Mice; Phenols; Prostaglandin-Endoperoxide Synthases; Skin; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1992 |
Chemoprevention of chemically induced skin tumor development by diallyl sulfide and diallyl disulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allyl Compounds; Animals; Antineoplastic Agents; Body Weight; Disulfides; Garlic; Mice; Papilloma; Plants, Medicinal; Skin Neoplasms; Sulfides; Tetradecanoylphorbol Acetate | 1992 |
Phenotypic expression of carcinogen-initiated epidermal cells to tumor cells by 12-O-tetradecanoylphorbol-13-acetate in a manner dependent on 3T3 fibroblast-derived humoral factor(s).
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; Epidermis; Macrophages; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in murine skin by systemic effects of ultraviolet irradiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays | 1992 |
Modification of tumor promotion in the mouse skin by exposure to an alternating magnetic field.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Electromagnetic Fields; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Enhanced papilloma formation in response to skin tumor promotion in transgenic mice overexpressing the human ornithine decarboxylase gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Epidermis; Gene Expression; Mice; Mice, Transgenic; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
An enzyme-linked immunosorbent assay for p65 oncofetal protein and its potential as a new marker for cancer risk assessment in rodents and humans.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Choline; Choline Deficiency; Diethylnitrosamine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Neoplasms; Oncogene Proteins; Rats; Rats, Inbred Strains; Risk Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Influences of sphingosine on two-stage skin tumorigenesis in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Body Weight; Carcinoma; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Sphingosine; Tetradecanoylphorbol Acetate | 1992 |
Carcinogenic and cocarcinogenic studies with carbaryl following topical exposure in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Carbaryl; Carcinogenicity Tests; Female; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
A model for initiated mouse skin: suppression of papilloma but not carcinoma formation by normal epidermal cells in grafts on athymic nude mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Fibroblasts; Genes, fos; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Papilloma; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate | 1992 |
Dietary energy and fat effects on tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Energy Intake; Enzyme Activation; Epidermis; Female; Mice; Phosphatidylinositols; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Differential effects of dietary linoleic acid on mouse skin-tumor promotion and mammary carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dietary Fats; Dinoprostone; Fatty Acids; Female; Linoleic Acid; Linoleic Acids; Mammary Neoplasms, Experimental; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Inhibitory effect of topical application of a green tea polyphenol fraction on tumor initiation and promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Edema; Enzyme Induction; Female; Flow Cytometry; Hydrogen Peroxide; Hyperplasia; Mice; Ornithine Decarboxylase; Phenols; Skin; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1992 |
Birth and death/differentiation rates of papillomas in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cell Death; Cell Differentiation; Drug Administration Schedule; Likelihood Functions; Mice; Models, Biological; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Abrogation of the suppressive effect of 12-O-tetradecanoylphorbol 13-acetate and 7,12-dimethylbenz[a]anthracene on footpad reaction of mice by indomethacin and some inhibitors of tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Drug Interactions; Hypersensitivity, Delayed; Indomethacin; Male; Mice; Mice, Inbred BALB C; Tetradecanoylphorbol Acetate | 1992 |
Alterations in protein kinase C isozymes alpha and beta 2 in activated Ha-ras containing papillomas in the absence of an increase in diacylglycerol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Codon; Diglycerides; Female; Genes, ras; Immune Sera; Isoenzymes; Mice; Mice, Inbred Strains; Molecular Sequence Data; Mutation; Papilloma; Peptides; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Metastatic potential of mouse skin carcinomas produced by different protocols of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; gamma-Glutamyltransferase; Lung Neoplasms; Methylnitronitrosoguanidine; Mice; Neoplasm Metastasis; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Oncogene alterations in in vitro transformed rat tracheal epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Cell Line; Cell Transformation, Neoplastic; DNA; Epithelium; Gene Amplification; Gene Rearrangement; Genes, ras; Male; Nucleic Acid Hybridization; Oncogene Protein p21(ras); Oncogenes; Polymorphism, Restriction Fragment Length; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-myc; Rats; RNA; Tetradecanoylphorbol Acetate; Trachea; Transfection | 1990 |
Tissue-specific expression of murine keratin K13 in internal stratified squamous epithelia and its aberrant expression during two-stage mouse skin carcinogenesis is associated with the methylation state of a distinct CpG site in the remote 5'-flanking reg
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinoma, Squamous Cell; Deoxyribonuclease I; DNA, Neoplasm; Epithelial Cells; Epithelium; Female; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Keratins; Methylation; Mice; Molecular Sequence Data; Nucleotides; Organ Specificity; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
TGF-beta 1 and skin carcinogenesis: antiproliferative effect in vitro and TGF-beta 1 mRNA expression during epidermal hyperproliferation and multistage tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Blotting, Northern; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Replication; DNA, Neoplasm; Female; Gene Expression; Keratinocytes; Mice; Mice, Inbred Strains; Phorbol Esters; RNA; RNA, Messenger; RNA, Neoplasm; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 1991 |
Identification of a cloned sequence activated during multi-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinoma, Squamous Cell; Gene Expression Regulation, Neoplastic; Keratins; Mice; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Altered regulation of growth and expression of differentiation-associated keratins in benign mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Division; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Keratins; Male; Mice; Mice, Hairless; Microscopy, Fluorescence; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
v-Ha-ras-induced mouse skin papillomas exhibit aberrant expression of keratin K13 as do their 7,12-dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate -induced analogues.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Blotting, Western; Fluorescent Antibody Technique; Gene Expression; Genes, ras; Keratinocytes; Keratins; Methylation; Mice; Molecular Sequence Data; Oligonucleotides; Oncogene Protein p21(ras); Oncogene Proteins v-fos; Papilloma; RNA, Messenger; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate | 1991 |
The chlorinated pesticide mirex is a novel nonphorbol ester-type tumor promoter in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Hyperplasia; Mice; Mice, Inbred Strains; Mirex; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Transplacental and transgeneration carcinogenic effect of 7,12-dimethylbenz[a]anthracene: relationship with ras oncogene activation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fetus; Gene Expression Regulation; Genes, ras; Lung Neoplasms; Male; Mice; Mutation; Neoplasms, Experimental; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1992 |
Prevalence of tumor prevention rather than tumor enhancement when repetitive UV radiation treatments precede initiation and promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinoma; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1992 |
Inhibitory effect of green tea in the drinking water on tumorigenesis by ultraviolet light and 12-O-tetradecanoylphorbol-13-acetate in the skin of SKH-1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drinking; Female; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Skin; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1992 |
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part II: Quantitation of glutathione and glutathione disulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Topical; Aging; Animals; Carcinoma, Squamous Cell; Epidermis; Female; Glutathione; Glutathione Disulfide; Mice; Oxidation-Reduction; Oxygen; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Concomitant proliferation and formation of a stratified epithelial sheet by explant outgrowth of epidermal keratinocytes from adult mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Female; Intercellular Junctions; Keratinocytes; Mice; Microscopy, Electron; Tetradecanoylphorbol Acetate | 1991 |
Cancer promotion in a mouse-skin model by a 60-Hz magnetic field: I. Experimental design and exposure system.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Electromagnetic Fields; Environmental Exposure; Mice; Research Design; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Cancer promotion in a mouse-skin model by a 60-Hz magnetic field: II. Tumor development and immune response.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Electromagnetic Fields; Female; Killer Cells, Natural; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Induction of CD8+ suppressor T cells by treatment with DMBA and TPA in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; CD4 Antigens; CD8 Antigens; Dose-Response Relationship, Drug; Hypersensitivity, Delayed; In Vitro Techniques; Macrophages; Major Histocompatibility Complex; Male; Mice; Mice, Inbred BALB C; Suppressor Factors, Immunologic; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 1991 |
Sterol and triterpene derivatives from plants inhibit the effects of a tumor promoter, and sitosterol and betulinic acid inhibit tumor formation in mouse skin two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Betulinic Acid; Female; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Pentacyclic Triterpenes; Phytosterols; Sitosterols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 1991 |
Promoter independence as a feature of most skin papillomas in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Genes, ras; Mice; Mutation; Neoplasm Regression, Spontaneous; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Effects of type of dietary fat on phorbol ester-elicited tumor promotion and other events in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinoma; Corn Oil; Dinoprostone; Female; Linoleic Acid; Linoleic Acids; Mice; Mice, Inbred DBA; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
The potent anti-tumor-promoting agent isoliquiritigenin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Aldehyde Reductase; Animals; Arachidonate 12-Lipoxygenase; Arachidonate 5-Lipoxygenase; Benz(a)Anthracenes; Blood Platelets; Chalcone; Chalcones; Dermatitis, Contact; Enzyme Induction; Female; Mice; Mice, Inbred Strains; Neutrophils; Ornithine Decarboxylase; Phospholipases A; Phospholipases A2; Prostaglandins; Skin; Skin Neoplasms; Sonication; Tetradecanoylphorbol Acetate | 1991 |
Evidence for a common genetic pathway controlling susceptibility to mouse skin tumor promotion by diverse classes of promoting agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; DNA; Dose-Response Relationship, Drug; Edema; Female; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1991 |
Influence of diet and calorie restriction on the initiation and promotion of skin carcinogenesis in the SENCAR mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinoma; Cocarcinogenesis; Diet; Energy Intake; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
[Genetics of cancerogenesis. Experimental model in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Drug Resistance; Incidence; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phenotype; Tetradecanoylphorbol Acetate | 1991 |
Urethan (ethyl carbamate) is an effective promoter of 7,12-dimethylbenz[a]anthracene-induced carcinogenesis in mouse skin two-stage experiments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Cocarcinogenesis; Female; Lung Neoplasms; Male; Mice; Mice, Hairless; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1991 |
Effect of dietary arginine restriction upon ornithine and polyamine metabolism during two-stage epidermal carcinogenesis in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arginine; DNA; Female; Mice; Ornithine; Ornithine Decarboxylase; Papilloma; Polyamines; Putrescine; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Inhibitory effects of new types of biflavonoid-related polyphenols; lophirone A and lophiraic acid, on some tumor promoter-induced biological responses in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzopyrans; Cocarcinogenesis; Enzyme Activation; Female; Flavonoids; Inflammation; Male; Mice; Mice, Inbred ICR; Papilloma; Phenols; Polymers; Protein Kinase C; Rats; Rats, Inbred WKY; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Inhibition of chemically-induced skin carcinogenesis in mice by peanut oil preparations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Arachis; Benzo(a)pyrene; Female; Male; Mice; Mice, Inbred C3H; Ornithine Decarboxylase; Plant Oils; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
The role of chronic acanthosis and subacute inflammation in tumor promotion in CD-1 mice by petroleum middle distillates.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acanthosis Nigricans; Administration, Topical; Animals; Body Weight; Carcinogens; Chronic Disease; Cocarcinogenesis; Dexamethasone; Dose-Response Relationship, Drug; Inflammation; Kerosene; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Tumor progression of murine epidermal cells after treatment in vitro with 12-O-tetradecanoylphorbol-13-acetate or retinoic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Synergism; Mice; Mice, Inbred BALB C; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1991 |
Overlapping loss of heterozygosity by mitotic recombination on mouse chromosome 7F1-ter in skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Base Sequence; Chromosome Mapping; DNA Probes; Genotype; Globins; Heterozygote; Mice; Mice, Inbred Strains; Mitosis; Molecular Sequence Data; Oligonucleotide Probes; Papilloma; Polymerase Chain Reaction; Recombination, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Cepharanthine inhibits two-stage tumor promotion by 12-O-tetradecanoylphorbol 13-acetate and mezerein on skin tumor formation in mice initiated with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Alkaloids; Animals; Benzylisoquinolines; Carcinogens; Diterpenes; Drug Interactions; Enzyme Induction; Female; Immunity, Cellular; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1991 |
[Presence of specific mutation of Ha-ras oncogene in skin tumors of mice induced under different experimental conditions].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Codon; Female; Genes, ras; Male; Mice; Mutation; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Constitutively elevated levels of ornithine and polyamines in mouse epidermal papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Guanosine Triphosphate; Mice; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Papilloma; Polyamines; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Tumor-promoting activity of ethyl phenylpropiolate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkynes; Animals; Carcinogens; Down-Regulation; Enzyme Induction; Female; Mice; Ornithine Decarboxylase; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
The effect of the level of dietary corn oil on mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Capillary Permeability; Cocarcinogenesis; Corn Oil; Dietary Fats; Dinoprostone; Fatty Acids; Female; Hyperplasia; Mice; Ornithine Decarboxylase; Phospholipids; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
Stimulation of in vivo tumor growth and phorbol ester-induced inflammation by N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine HCl, a potent ligand for intracellular histamine receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Drug Synergism; Epithelium; Female; Histamine Antagonists; Hyperplasia; Inflammation; Leukemia L5178; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred DBA; Mitotic Index; Phenyl Ethers; Rats; Rats, Inbred Strains; Receptors, Histamine; Skin; Tetradecanoylphorbol Acetate | 1991 |
Differential oxidative stress induced by two different types of skin tumor promoters, benzoyl peroxide and 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Benzoyl Peroxide; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Luminescent Measurements; Mice; Mice, Inbred Strains; Oxidation-Reduction; Salicylates; Skin; Tetradecanoylphorbol Acetate | 1991 |
Absence of the c-Ha-ras codon 61 point mutation in murine solid tumors induced by subcutaneously applied 7,12-dimethylbenzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Base Sequence; Codon; Female; Fibrosarcoma; Gene Expression Regulation, Neoplastic; Genes, ras; Heterozygote; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Oncogenes; Polymorphism, Restriction Fragment Length; Tetradecanoylphorbol Acetate | 1990 |
Modulation of the co-promoting activity of gamma interferon in SENCAR and C57BL/6 mouse skin by difluoromethylornithine and the scheduling and duration of interferon treatment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Eflornithine; Female; Interferon-gamma; Kinetics; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Recombinant Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chamomile; Cocarcinogenesis; Dose-Response Relationship, Drug; Enzyme Induction; Epidermis; Flavonoids; Mice; Oils, Volatile; Ornithine Decarboxylase; Papilloma; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Sensitivity of subpopulations of mouse skin papillomas to malignant conversion by urethane or 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Survival Analysis; Tetradecanoylphorbol Acetate; Time Factors; Urethane | 1990 |
Anti-tumor promoting action of phthalic acid mono-n-butyl ester cupric salt, a biomimetic superoxide dismutase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Cells, Cultured; Dermatitis, Contact; Dibutyl Phthalate; Ear Diseases; Edema; Enzyme Induction; Epidermal Cells; Epidermis; Female; Mice; Ornithine Decarboxylase; Papilloma; Phthalic Acids; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1990 |
Comparison of the effects of bilobol and 12-O-tetradecanoylphorbol-13-acetate on skin, and test of tumor promoting potential of bilobol in CD-1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Irritants; Mice; Resorcinols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Effects of beta-carotene on chemically-induced skin tumors in HRA/Skh hairless mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Body Weight; Carotenoids; Diet; Female; Mice; Mice, Hairless; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Antitumor activity in skin of Skh and Sencar mice by two dietary beta-carotene formulations.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Body Weight; Carotenoids; Diet; Female; Food, Fortified; Mice; Mice, Inbred Strains; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Inhibitory effects of flavonol glycosides on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cocarcinogenesis; Enzyme Induction; Female; Flavonoids; Glycosides; Immunity, Cellular; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Tetradecanoylphorbol Acetate | 1990 |
Effects of antihistamines on phorbol ester tumor promotion and vascular permeability changes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capillary Permeability; Cimetidine; Diphenhydramine; Female; Indomethacin; Inflammation; Masoprocol; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Mouse skin ornithine decarboxylase induction and tumor promotion by cyclohexane.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Cyclohexanes; Cycloheximide; Environmental Exposure; Enzyme Induction; Female; Mice; Ornithine Decarboxylase; Protein Biosynthesis; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
S/RV Cri-ba, a hairless mouse strain sensitive to skin tumorigenesis by suboptimal doses of 7,12-dimethylbenz[a]anthracene, initiation-promotion and two stage promotion protocols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cocarcinogenesis; Diterpenes; Dose-Response Relationship, Drug; Female; Mice; Mice, Hairless; Papilloma; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1990 |
Development of an in vitro analogue of initiated mouse epidermis to study tumor promoters and antipromoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Antineoplastic Agents; Benzoyl Peroxide; Carcinogens; Cell Communication; Cell Division; Cell Line; Cells, Cultured; Clone Cells; Diterpenes; Keratinocytes; Mice; Mice, Inbred BALB C; Phorbol Esters; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1990 |
Morphometric evaluation of dark and clear epidermal basal cells during early 2-stage chemical skin carcinogenesis in the hairless mouse using two different fixation methods.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Membrane; Cell Nucleus; Cocarcinogenesis; Cytoplasm; Desmosomes; Epidermis; Extracellular Space; Fixatives; Keratinocytes; Mice; Mice, Mutant Strains; Microscopy, Electron; Mitochondria; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Genetics of chemical carcinogenesis. 1. Bidirectional selective breeding of susceptible and resistant lines of mice to two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Crosses, Genetic; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Immunity, Innate; Male; Mice; Mice, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1990 |
Papilloma and carcinoma production in DMBA-initiated, onion oil-promoted mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allium; Animals; Carcinoma; Cell Transformation, Neoplastic; Female; Garlic; Mice; Papilloma; Plant Oils; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Increased sensitivity to two-stage skin carcinogenesis of mice heterozygous for the repeated epilation mutation (Er).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hair Removal; Heterozygote; Male; Mice; Mice, Inbred BALB C; Mutation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Elevated expression of secondary, but not early, responding genes to phorbol ester tumor promoters in papillomas and carcinomas of mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Northern; Carcinogens; Carcinoma; Female; Gene Expression; Metallothionein; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Osteopontin; Papilloma; Proto-Oncogene Proteins; RNA, Messenger; Sialoglycoproteins; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transforming Growth Factors; Tubulin; Urokinase-Type Plasminogen Activator | 1990 |
Effects of 2-phenyl-1,4-benzoquinone and 2,5-dihydroxybiphenyl on two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoquinones; Biphenyl Compounds; Epidermis; Female; Hydroquinones; Incidence; Mice; Mice, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Evidence that weak promotion of carcinogen-initiated cells prevents their progression to malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; Benzyl Alcohols; Cell Transformation, Neoplastic; Cortisone; Dose-Response Relationship, Drug; Indoles; Mice; Mice, Inbred BALB C; Papilloma; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin E | 1990 |
Suppression of footpad reaction in mice by anthralin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Erythrocytes; Hindlimb; Hypersensitivity, Delayed; Isoantibodies; Male; Mice; Mice, Inbred BALB C; Skin Neoplasms; Spleen; Tetradecanoylphorbol Acetate | 1990 |
Nicotinamide and nicotinamide analogues as antitumor promoters in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminobenzoates; Animals; Antineoplastic Agents; Benzamides; Benzoates; Benzoic Acid; Cell Division; Clone Cells; DNA Replication; Female; Keratinocytes; Kinetics; meta-Aminobenzoates; Mice; Mice, Inbred Strains; Niacinamide; Papilloma; Poly(ADP-ribose) Polymerase Inhibitors; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Mechanism of suppression of footpad reaction in mice by 12-tetradecanoylphorbol 13-acetate and 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Carcinogens; Cell Adhesion; Erythrocytes; Foot; Immune Tolerance; Immunization, Passive; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred BALB C; Sheep; Skin; Spleen; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 1990 |
Absence of papillomavirus in skin tumors induced in SENCAR mice by a two-stage carcinogenesis protocol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; DNA, Viral; Female; Mice; Papilloma; Papillomaviridae; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1990 |
Studies on the anti-tumor-promoting activity of naturally occurring substances. IV. Pd-II [(+)anomalin, (+)praeruptorin B], a seselin-type coumarin, inhibits the promotion of skin tumor formation by 12-O-tetradecanoylphorbol-13-acetate in 7,12-dimethylben
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Cell Line; Coumarins; Drugs, Chinese Herbal; Female; HeLa Cells; Herpesvirus 4, Human; Humans; Mice; Mice, Inbred ICR; Phosphates; Phospholipids; Skin Neoplasms; Tetradecanoylphorbol Acetate; Virus Activation | 1990 |
Identification of a serum-inducible messenger RNA (5B10) as the mouse homologue of calcyclin: tissue distribution and expression in metastatic, ras-transformed NIH 3T3 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Base Sequence; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chick Embryo; Fibroblasts; Gene Expression Regulation; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Transplantation; Oncogene Protein p21(ras); Organ Specificity; S100 Calcium Binding Protein A6; S100 Proteins; Simian virus 40; Species Specificity; Tetradecanoylphorbol Acetate | 1990 |
Induction of papillomas with a high probability of conversion to malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Diterpenes; DNA; Female; Keratins; Mice; Mice, Inbred Strains; Papilloma; Probability; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanoylphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dose-Response Relationship, Drug; Enzyme Induction; Female; Histamine Release; Histidine Decarboxylase; Irritants; Lactones; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Plant Extracts; Sesquiterpenes; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tritium | 1986 |
Distribution, covalent binding, and DNA adduct formation of 7,12-dimethylbenz(a)anthracene in SENCAR and BALB/c mice following topical and oral administration.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; DNA; Mice; Mice, Inbred BALB C; Protein Binding; RNA; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1987 |
Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Carcinoma; Cell Transformation, Neoplastic; Female; Gene Expression Regulation; Genes; Keratins; Mice; Mice, Inbred Strains; Nucleic Acid Hybridization; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Sequential development of aneuploidy, keratin modifications, and gamma-glutamyltransferase expression in mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; gamma-Glutamyltransferase; Immunoenzyme Techniques; Keratins; Metaphase; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Quantitation of primary in vitro clonogenic keratinocytes from normal adult murine epidermis, following initiation, and during promotion of epidermal tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Colony-Forming Units Assay; Epidermis; Female; Keratins; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay | 1988 |
Gap-junctional intercellular communication in epidermal cell lines from selected stages of SENCAR mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Calcium; Cell Communication; Cell Line; Epidermis; Intercellular Junctions; Keratins; Mice; Microinjections; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on macromolecular synthesis in epidermis, dermis and subcutis from mouse skin initiated with 7,12-dimethylbenz(a) anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA; Epidermis; Female; Mice; Protein Biosynthesis; RNA; Skin; Tetradecanoylphorbol Acetate | 1988 |
The influence of fixation on the relative amount of cytoplasmic ribosomes in mouse epidermal basal keratinocytes. A morphometric study of so-called "dark cells" and their putative role in epidermal carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cytoplasm; Epidermal Cells; Epidermis; Female; Fixatives; Keratins; Male; Mice; Mice, Hairless; Microscopy, Electron; Ribosomes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Dietary fat effects on the initiation and promotion of two-stage skin tumorigenesis in the SENCAR mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Dietary Fats; Energy Intake; Female; Genes, ras; Mice; Papilloma; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Modulation by adriamycin, daunomycin, verapamil, and trifluoperazine of the biochemical processes linked to mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Daunorubicin; DNA; Doxorubicin; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Trifluoperazine; Verapamil | 1989 |
Multistage chemical carcinogenesis protocols produce spindle cell carcinomas of the mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinoma; Drug Administration Schedule; Immunoenzyme Techniques; Keratins; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Induction of terminal differentiation-resistant epidermal cells in mouse skin and in papillomas by different initiators during two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Epidermal Cells; Female; Methylnitronitrosoguanidine; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Antitumor-promoting activity of eperisone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Calcium Channel Blockers; Female; HeLa Cells; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Phosphates; Phospholipids; Propiophenones; Tetradecanoylphorbol Acetate | 1989 |
Tumor copromoting activity of gamma-interferon in the murine skin multistage carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Interferon-gamma; Mice; Papilloma; Recombinant Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Roussin red methyl ester, a tumor promoter isolated from pickled vegetables.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Esophageal Neoplasms; Nitroso Compounds; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vegetables | 1989 |
Tumor prevention by a xanthate compound in experimental mouse-skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antineoplastic Agents; Antiviral Agents; Bridged-Ring Compounds; Carcinoma; Dose-Response Relationship, Drug; Female; Mice; Norbornanes; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones | 1989 |
Dose and frequency effect in mouse skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Statistics as Topic; Tetradecanoylphorbol Acetate | 1989 |
Tumor induction in initiated mouse skin by phorbol esters and methyl methanesulfonate: correlation between chromosomal damage and conversion ('stage I of tumor promotion') in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chromosome Aberrations; Female; Methyl Methanesulfonate; Mice; Phorbol Esters; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Further characterization of skin tumor promotion and progression by mezerein in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Diterpenes; DNA; Female; Mice; Papilloma; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Acceleration of papilloma growth in mice fed high-fat diets during promotion of two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cocarcinogenesis; Dietary Fats; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Sodium o-phenylphenate (OPP-Na) promotes skin carcinogenesis in CD-1 female mice initiated with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biphenyl Compounds; Carcinoma; Drug Synergism; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Antitumor-promoting activity of garlic extracts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Garlic; HeLa Cells; Mice; Mice, Inbred ICR; Phospholipids; Phosphorus Radioisotopes; Plant Extracts; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Effects of oral versus topical administration of cyclosporine on phorbol ester promotion of murine epidermal carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cyclosporins; Hyperplasia; Male; Mice; Neutrophils; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Regulation of ornithine decarboxylase in normal and neoplastic mouse and human epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Chromatography, Gel; Epidermis; Female; Humans; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Developing design standards for dermal initiation/promotion screening studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinogenicity Tests; Female; Male; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Research Design; Skin; Tetradecanoylphorbol Acetate | 1989 |
Model systems for defining initiation, promotion, and progression of skin neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cell Division; Cocarcinogenesis; Cricetinae; Disease Models, Animal; Hyperplasia; Inflammation; Mesocricetus; Mice; Mutagenicity Tests; Neoplasms, Radiation-Induced; Salmonella typhimurium; Skin; Skin Neoplasms; Solvents; Species Specificity; Tetradecanoylphorbol Acetate; Turpentine; Ultraviolet Rays | 1989 |
Tumor initiation in mouse skin by cutting oils.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Hyperplasia; Industrial Oils; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Inhibition of initiator-promoter-induced skin tumorigenesis in female SENCAR mice fed a vitamin A-deficient diet and reappearance of tumors in mice fed a diet adequate in retinoid or beta-carotene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carotenoids; Cocarcinogenesis; Diet; Female; Liver; Male; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A Deficiency; Weight Loss | 1989 |
Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Amidines; Animals; Benzoyl Peroxide; Carcinogens; Cell Transformation, Neoplastic; Female; Free Radicals; Mice; Mice, Hairless; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Papilloma; Peroxides; Skin; Skin Diseases; Skin Neoplasms; tert-Butylhydroperoxide; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1989 |
Comparison of octahydromezerein and mezerein as protein kinase C activators and as mouse skin tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diterpenes; Enzyme Activation; Female; Hyperplasia; Mice; Mice, Inbred Strains; Papilloma; Protein Kinase C; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Increased tumour incidence and skin tumour promotion in two generations of descendants of 7,12-dimethylbenz[a]anthracene-treated pregnant mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Male; Mice; Neoplasms, Experimental; Pedigree; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Consistent oncogene methylation changes in epithelial cells chemically transformed in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Benzo(a)pyrene; Blotting, Southern; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; DNA; Epithelial Cells; Epithelium; Genes, ras; Male; Methylation; Proto-Oncogenes; Rats; Rats, Inbred F344; Restriction Mapping; Tetradecanoylphorbol Acetate; Trachea | 1989 |
Tumor associated proteins of rat skin tumor induced by 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Carcinoma, Squamous Cell; Cell Membrane; Glycoproteins; Membrane Proteins; Papilloma; Rats; Rats, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Biological assays for irritant, tumor-initiating and tumor-promoting activities. II. Standardized initiation/promotion protocol and semiquantitative estimation of promoting (or initiating) potencies in skin of NMRI mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Cocarcinogenesis; Female; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1989 |
Inhibition of 7,12-dimethylbenz[a]anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate-promoted skin papilloma formation in mice by dehydroepiandrosterone and two synthetic analogs.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Dehydroepiandrosterone; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1989 |
Differential inhibition by staurosporine, a potent protein kinase C inhibitor, of 12-O-tetradecanoylphorbol-13-acetate-caused skin tumor promotion, epidermal ornithine decarboxylase induction, hyperplasia and inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Edema; Enzyme Induction; Female; Hyperplasia; Inflammation; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Reference Values; Skin; Skin Neoplasms; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
[Anti-tumor promoting activities and inhibitory effects on Epstein-Barr virus activation of Shi-un-kou and its constituents].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Depression, Chemical; Drugs, Chinese Herbal; Female; Herpesvirus 4, Human; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Virus Activation | 1989 |
Analysis of the rasH oncogene and its p21 product in chemically induced skin tumors and tumor-derived cell lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Line; Deoxyribonucleases, Type II Site-Specific; DNA Restriction Enzymes; DNA, Neoplasm; Female; Mice; Oncogenes; Papilloma; Polymorphism, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1987 |
Sequential study of gamma-glutamyltransferase during complete and two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Female; gamma-Glutamyltransferase; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Malignant progression of mouse skin papillomas treated with ethylnitrosourea, N-methyl-N'-nitro-N-nitrosoguanidine, or 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Ethylnitrosourea; Female; gamma-Glutamyltransferase; Methylnitronitrosoguanidine; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Palytoxin is a non-12-O-tetradecanoylphorbol-13-acetate type tumor promoter in two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acrylamides; Animals; Carcinogens; Cnidarian Venoms; Enzyme Induction; Female; Lyngbya Toxins; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Response of carcinogen-altered mouse epidermal cells to phorbol ester tumor promoters and calcium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Carcinogens; Cell Differentiation; Cell Division; Cell Line; Cocarcinogenesis; Colony-Forming Units Assay; Drug Interactions; Epidermal Cells; Epidermis; Methylnitronitrosoguanidine; Mice; Tetradecanoylphorbol Acetate; Transglutaminases | 1987 |
[Effect of applications of TPA for GGT-positive foci during DMBA-induced cheek pouch carcinogenesis of the hamster].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cricetinae; gamma-Glutamyltransferase; Mouth Mucosa; Mouth Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Transplacental induction of a specific mutation in fetal Ha-ras and its critical role in post-natal carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinoma; Cocarcinogenesis; DNA, Neoplasm; Female; Mice; Mutation; Papilloma; Polymorphism, Restriction Fragment Length; Pregnancy; Prenatal Exposure Delayed Effects; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Proto-Oncogenes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Qualitative and quantitative effects on epidermal Langerhans (Ia+) and Thy-1+ dendritic cells following topical application of phorbol diesters and mezerein.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Carcinogens; Dendritic Cells; Diterpenes; Histocompatibility Antigens Class II; Langerhans Cells; Mice; Skin; Terpenes; Tetradecanoylphorbol Acetate; Thy-1 Antigens | 1988 |
Glycyrrhetic acid inhibits tumor-promoting activity of teleocidin and 12-O-tetradecanoylphorbol-13-acetate in two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; ErbB Receptors; Female; Glycyrrhetinic Acid; HeLa Cells; Lyngbya Toxins; Mice; Mice, Inbred ICR; Phorbols; Phospholipids; Phosphorus Radioisotopes; Quercetin; Receptors, Cell Surface; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Cholera toxin, a potent inducer of epidermal hyperplasia but with no tumor promoting activity in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cholera Toxin; Cocarcinogenesis; Cyclic AMP; Diterpenes; Enzyme Induction; Epidermis; Hyperplasia; Mice; Ornithine Decarboxylase; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1986 |
Epidermal changes following application of 7,12-dimethylbenz(a)anthracene and 12-O-tetradecanoylphorbol-13-acetate to human skin transplanted to nude mice studied with histological species markers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aged; Animals; Epidermis; Female; Humans; Hyperplasia; Male; Mice; Mice, Nude; Middle Aged; Skin Neoplasms; Skin Transplantation; Species Specificity; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1986 |
Inhibitory effect of toluene on tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Drug Antagonism; Male; Mice; Mice, Inbred C3H; Phorbols; Skin Neoplasms; Solvents; Tetradecanoylphorbol Acetate; Toluene | 1986 |
The role of prostaglandin E1 in ornithine decarboxylase induction by tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alprostadil; Animals; Diterpenes; Enzyme Induction; Female; Indomethacin; Mice; Mice, Inbred Strains; Models, Biological; Neoplasms; Ornithine Decarboxylase; Phorbols; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Berberine sulfate inhibits tumor-promoting activity of teleocidin in two-stage carcinogenesis on mouse skin.
Topics: 3-O-Methylglucose; 9,10-Dimethyl-1,2-benzanthracene; Animals; Berberine; Berberine Alkaloids; Biological Transport; Carcinogens; Cells, Cultured; Female; Fibroblasts; HeLa Cells; In Vitro Techniques; Lyngbya Toxins; Methylglucosides; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Phosphates; Phospholipids; Radioisotopes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Histogenesis of the intradermal melanocytic tumor in BDF1 mice induced by topical application of 9,10-dimethyl-1,2-benzanthracene (DMBA) and 12-O-tetradecanoylphorbol-13-acetate (TPA).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Melanocytes; Melanoma; Mice; Mice, Inbred Strains; Microscopy, Electron; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Influence of the duration of topical 13-cis-retinoic acid treatment on inhibition of mouse skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; DNA; Female; Isotretinoin; Mice; Mice, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1986 |
Enhanced malignant progression of mouse skin tumors by the free-radical generator benzoyl peroxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Cocarcinogenesis; Female; Free Radicals; Keratoacanthoma; Mice; Mice, Inbred Strains; Papilloma; Peroxides; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Three-stage tumorigenesis in mouse skin: DNA synthesis as a prerequisite for the conversion stage induced by TPA prior to initiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; DNA; Female; Hydroxyurea; Mice; Mice, Inbred Strains; Phorbol Esters; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
[Activation of protein kinase by estradiol in plasma membranes of estradiol-dependent tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Estradiol; Mammary Neoplasms, Experimental; Membrane Proteins; Neoplasms, Hormone-Dependent; Phosphorylation; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1986 |
Inhibition of the prenatal dimethylbenz[a]anthracene-induced tumour initiation in mice by prior administration of 7,8-benzoflavone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Administration, Oral; Animals; Benzoflavones; Cocarcinogenesis; Female; Flavonoids; Lung Neoplasms; Mice; Neoplasms, Experimental; Papilloma; Pregnancy; Prenatal Exposure Delayed Effects; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
3-Amino-1-methyl-5H-pyrido[4,3-b]-indole initiates two-stage carcinogenesis in mouse skin but is not a complete carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carbolines; Carcinogens; Cocarcinogenesis; Dimethyl Sulfoxide; Female; Mice; Mice, Inbred Strains; Mutagens; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Retinoic acid enhancement of an early step in the transformation of mouse epidermal cells in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Dose-Response Relationship, Drug; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Hyperthermia and phorbol ester tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Female; Hyperthermia, Induced; Mice; Papilloma; Phorbols; Skin; Skin Neoplasms; Skin Temperature; Tetradecanoylphorbol Acetate | 1986 |
Effects of 12-O-tetradecanoylphorbol-13-acetate on carcinogen-induced mouse mammary lesions in organ culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Drug Synergism; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Tetradecanoylphorbol Acetate | 1986 |
Cell-mediated immune response in mice during the two-step carcinogenesis experiment by 7,12-dimethylbenz(a)anthracene and 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens; Dinitrofluorobenzene; Erythrocytes; Female; Hypersensitivity, Delayed; Immunity, Cellular; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Inhibition and enhancement of skin tumors in mice by dimethyl sulfoxide depending on method of application.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Dimethyl Sulfoxide; Drug Interactions; Male; Mice; Skin Neoplasms; Solvents; Tetradecanoylphorbol Acetate | 1986 |
Differential carcinogenic effects of intraperitoneal initiation with 7,12-dimethylbenz(a)anthracene or urethane and topical promotion with 12-O-tetradecanoylphorbol-13-acetate in skin and internal tissues of female SENCAR and BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Cocarcinogenesis; Female; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Neoplasms, Experimental; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Urethane | 1986 |
Tumorigenesis in athymic nude mouse skin by chemical carcinogens and ultraviolet light.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Disease Susceptibility; Ear Neoplasms; Ethylnitrosourea; Female; Heterozygote; Male; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Radiation-Induced; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1987 |
Sebaceous adenomas with associated epidermal hyperplasia and papilloma formation as a major type of tumor induced in mouse skin by high doses of carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinoma; Epidermis; Hyperplasia; Mice; Mice, Nude; Papilloma; Sebaceous Gland Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1986 |
Sequential studies of skin tumorigenesis in phosphoglycerate kinase mosaic mice: effect of resumption of promotion on regressed papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Mice; Mice, Inbred BALB C; Mosaicism; Papilloma; Phosphoglycerate Kinase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Promotion of skin tumours by TPA in the progeny of mice exposed pre-natally to DMBA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Crosses, Genetic; Female; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: relevance to malignancy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Carcinoma, Squamous Cell; Cell Nucleus; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Mastocytoma induced by cigarette smoke particulates: "cigarette tar".
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Mastocytosis; Mice; Nicotiana; Plants, Toxic; Tars; Tetradecanoylphorbol Acetate | 1986 |
Presence of tumor promoters in the seed oil of Jatropha curcas L. from Thailand.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Irritants; Mice; Ornithine Decarboxylase; Plant Oils; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thailand | 1987 |
Evaluation of epidermal cell kinetics following freezing or wounding of mouse skin and their potential as initiators of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Epidermal Cells; Female; Freezing; Hyperplasia; Mice; Mice, Inbred Strains; Skin; Skin Neoplasms; Skin Ulcer; Tetradecanoylphorbol Acetate; Time Factors; Wounds, Penetrating | 1987 |
Characterization of skin tumor promotion and progression by chrysarobin in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
A novel system for studying in vivo effects of tumor promoters on DNA tumor viruses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cocarcinogenesis; Cricetinae; DNA Tumor Viruses; DNA, Viral; Drug Interactions; Male; Mesocricetus; Papilloma; Papillomaviridae; Polyomaviridae; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Sequential studies of skin tumorigenesis in PGK mosaic mice: the effect of repeated exposure to a carcinogen on regressed mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Interactions; Mice; Mice, Inbred BALB C; Mosaicism; Papilloma; Phenotype; Phosphoglycerate Kinase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Elevated expression and point mutation of the Ha-ras proto-oncogene in mouse skin tumors promoted by benzoyl peroxide and other promoting agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Female; Gene Expression Regulation; Mice; Mutation; Papilloma; Peroxides; Proto-Oncogenes; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Comparison of sensitivity of Swiss albino and hairless Swiss bare mice to two stage skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Susceptibility; Female; Male; Mice; Mice, Hairless; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1987 |
Induction of melanogenesis in Schwann cell and perineural epithelium by 9,10-dimethyl-1,2-benzanthracene (DMBA) and 12-o-tetradecanoylphorbol-13-acetate (TPA) in BDF1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Epithelium; Female; Melanocytes; Mice; Mice, Inbred Strains; Schwann Cells; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Tumorigenesis and carcinogenesis in mouse skin treated with hyperthermia during stage I or stage II of tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hyperthermia, Induced; Mice; Peptide Hydrolases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Persistence of carcinogenic effect in intact progeny of mice treated transplacentally with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fetus; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms, Experimental; Pregnancy; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Development of murine epidermal cell lines which contain an activated rasHa oncogene and form papillomas in skin grafts on athymic nude mouse hosts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Calcium; Cell Line; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Oncogenes; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 1988 |
The tumor-initiating and -promoting effects of ionizing radiations in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Mice; Mice, Inbred ICR; Neoplasms, Radiation-Induced; Radiation, Ionizing; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1987 |
Inhibition of mouse skin tumor promotion and of promoter-induced epidermal polyamine biosynthesis by methylglyoxal bis(butylamidinohydrazone).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Male; Mice; Mice, Inbred Strains; Mitoguazone; Ornithine Decarboxylase Inhibitors; Papilloma; Polyamines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
The influence of a hyperthermia treatment on chemically induced tumor initiation and progression in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; DNA Repair; Female; Glutathione; Hyperthermia, Induced; Methylnitronitrosoguanidine; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Enzyme Induction; Ethers, Cyclic; Humans; Leukemia, Myeloid, Acute; Lyngbya Toxins; Mice; Okadaic Acid; Ornithine Decarboxylase; Porifera; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Oncogene transcription in normal human IMR-90 fibroblasts: induction by serum and tetradecanoyl phorbol acetate.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Blood; Cell Line; Fibroblasts; Humans; Oncogenes; Phorbol Esters; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Susceptibility to phorbol ester skin tumor promotion in (C57BL/6 x DBA/2) F1 mice is inherited as an incomplete dominant trait: evidence for multi-locus involvement.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Crosses, Genetic; Genes, Dominant; Male; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1988 |
Influence of dose of initiator on two-stage skin carcinogenesis in BALB/c mice with cellular mosaicism.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred BALB C; Mosaicism; Papilloma; Phenotype; Phosphoglycerate Kinase; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1988 |
Comparison of the inhibitory effects of retinoids on 12-O-tetradecanoylphorbol-13-acetate-promoted tumor formation in CD-1 and Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Mice; Mice, Inbred Strains; Papilloma; Retinoids; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1988 |
Sensitivity of HRA/Skh hairless mice to initiation/promotion of skin tumors by chemical treatment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Dose-Response Relationship, Drug; Mice; Mice, Hairless; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Suppression of footpad reaction in mice by 12-tetradecanoylphorbol 13-acetate and 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Erythrocytes; Foot; Hypersensitivity, Delayed; Immunization, Passive; Male; Mice; Mice, Inbred BALB C; Sheep; Spleen; Tetradecanoylphorbol Acetate | 1988 |
Sensitivity of the skin of different mouse strains to the promoting effect of 12-0-tetradecanoyl-phorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Papilloma; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1988 |
Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Catechols; Chlorogenic Acid; Cinnamates; Coumaric Acids; Curcumin; DNA; Edema; Female; Mice; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Effect of flavonoids on tumor promoter's activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Cocarcinogenesis; Flavonoids; Inflammation; Mice; Mice, Inbred ICR; Tetradecanoylphorbol Acetate | 1988 |
Role of cutaneous GSH in 12-O-tetradecanoyl-phorbol 13-acetate-induced mouse skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Glutathione; Maleates; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Stimulation of hydroperoxide generation in mouse skins treated with tumor-promoting or carcinogenic agents in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epidermis; Free Radicals; In Vitro Techniques; Mice; Peroxides; Skin; Tetradecanoylphorbol Acetate | 1988 |
Tumor progression in Sencar mouse skin as a function of initiator dose and promoter dose, duration, and type.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Carcinogens; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1988 |
[Inhibitory effect of glycyrrhizin and caffeine on two-stage carcinogenesis in mice].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Infective Agents; Caffeine; Cocarcinogenesis; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Expression pattern of a gene for a secreted metalloproteinase during late stages of tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Carcinoma, Squamous Cell; Cloning, Molecular; DNA, Neoplasm; Female; Gene Amplification; Gene Rearrangement; Immunoblotting; Matrix Metalloproteinase 3; Metalloendopeptidases; Mice; Molecular Sequence Data; Multigene Family; Neoplasm Proteins; Papilloma; Peptide Hydrolases; Plasmids; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1988 |
Tumorigenic and molecular characterization of novel phorbol ester-resistant and -sensitive lines of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Autoradiography; Brain; Breeding; Carcinogenicity Tests; Drug Resistance; Epidermis; Female; Male; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phorbol Esters; Phosphorylation; Protein Kinase C; Skin Neoplasms; Substrate Specificity; Tetradecanoylphorbol Acetate | 1988 |
Effects of short-term exposure to the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate on skin carcinogenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Female; Mice; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Tumor-promoting effects of di(2-ethylhexyl)phthalate in JB6 mouse epidermal cells and mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Epidermis; Female; Mice; Phthalic Acids; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
In vivo studies on enhancement and promotion of respiratory tract carcinogenesis: studies with heterotopic tracheal transplants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Epithelium; Formaldehyde; Rats; Rats, Inbred F344; Respiratory Tract Neoplasms; Tetradecanoylphorbol Acetate; Trachea | 1985 |
Proto-oncogene expression during two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Female; Gene Expression Regulation; Mice; Oncogenes; Papilloma; RNA, Neoplasm; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Two-stage tumor promotion in mouse skin: an alternative interpretation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Croton Oil; Fluocinolone Acetonide; Mice; Mice, Inbred Strains; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1985 |
12-O-tetradecanoylphorbol-13-acetate-induced rapid loss of persistent 7,12-dimethylbenz[a]anthracene-DNA adducts in mouse epidermis and dermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; DNA; Epidermis; Female; Mice; Mice, Inbred BALB C; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Soft agar colony formation of mouse epidermal cells during the early phase of two-stage chemically induced carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Agar; Animals; Cocarcinogenesis; Colony-Forming Units Assay; Epidermis; Male; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Stem Cell Assay | 1985 |
Effects of a biomimetic superoxide dismutase on complete and multistage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biotransformation; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1985 |
Stimulatory effect of 1 alpha, 25-dihydroxyvitamin D3 on the formation of skin tumors in mice treated chronically with 7,12-dimethylbenz[a]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Body Weight; Calcitriol; Cocarcinogenesis; Female; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1985 |
Partial inversion of the initiation-promotion sequence of multistage tumorigenesis in the skin of NMRI mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Diterpenes; Female; Mice; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
12-O-tetradecanoylphorbol-13-acetate promotes tumors prior to initiation in two-stage promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Diterpenes; Enzyme Induction; Female; Mice; Models, Biological; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1985 |
Initiation and promotion in young and old animals. Implications for human tumour formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Autopsy; Female; Humans; Mathematics; Mice; Models, Biological; Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1985 |
Effect of an anticancer agent, vinblastine, on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cell Transformation, Viral; Female; Herpesvirus 4, Human; Hyperplasia; Mice; Skin; Tetradecanoylphorbol Acetate; Vinblastine; Virus Activation | 1984 |
Irritant diterpene ester promoters of mouse skin: contributions to etiologies of environmental cancer and to biochemical mechanisms of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Affinity Labels; Animals; Biotransformation; Caenorhabditis elegans Proteins; Carcinogens, Environmental; Carrier Proteins; Diterpenes; Electron Spin Resonance Spectroscopy; Humans; Irritants; Mice; Neoplasms; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1983 |
Chemical carcinogenesis by the two-stage protocol in the skin Mastomys natalensis (Muridae) using topical initiation with 7,12-dimethylbenz(a)anthracene and topical promotion with 12-0-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Keratoacanthoma; Male; Muridae; Neoplasms, Experimental; Phorbols; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Hairless mouse skin in two-stage chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Drug Resistance; Female; Hyperplasia; Male; Mice; Mice, Hairless; Neoplasm Regression, Spontaneous; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
The effect of carcinogens on the accumulation of tyrosine aminotransferase by foetal rat hepatocytes in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cells, Cultured; Fetus; Liver; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Rats; Rats, Inbred Strains; Receptors, Steroid; Tetradecanoylphorbol Acetate; Tyrosine Transaminase | 1982 |
Comparison of the effects of 3-isobutyl-1-methylxanthine and adenosine cyclic 3':5'-monophosphate on the induction of skin tumors by the initiation-promotion protocol and by the complete carcinogenesis process.
Topics: 1-Methyl-3-isobutylxanthine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cyclic AMP; DNA; Female; In Vitro Techniques; Mice; Mice, Inbred Strains; Polyamines; Protein Biosynthesis; RNA; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Theophylline | 1982 |
Simultaneous appearance of keratin modifications and gamma-glutamyltransferase activity as indicators of tumor progression in mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acyltransferases; Animals; Carcinoma, Squamous Cell; Female; Histocytochemistry; Keratins; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transglutaminases | 1983 |
Effect of hexachlorocyclohexane on diethylnitrosamine-induced hepatocarcinogenesis in rat and its failure to promote skin tumors on dimethylbenz[a]anthracene initiation in mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Diethylnitrosamine; Drug Interactions; Female; gamma-Glutamyltransferase; Hexachlorocyclohexane; Liver; Liver Neoplasms, Experimental; Nitrosamines; Phorbols; Rats; Rats, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1984 |
Differentiation of cultured epidermal keratinocytes related to sterol metabolism and its retardation by chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Acetic Acid; Aging; Animals; Carcinogens; Cell Differentiation; Cholesterol; Epidermal Cells; Epidermis; Keratins; Mice; Mice, Inbred BALB C; Sterols; Tetradecanoylphorbol Acetate | 1984 |
Dehydroepiandrosterone (DHEA) and 3 beta-methylandrost-5-en-17-one: inhibitors of 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)-promoted skin papilloma formation in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenes; Animals; Benz(a)Anthracenes; Dehydroepiandrosterone; Drug Administration Schedule; Drug Antagonism; Estradiol; Female; Mice; Papilloma; Phorbols; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Uterus | 1984 |
Further investigations of the capacity of polynuclear aromatic hydrocarbons to elicit atherosclerotic lesions.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aorta, Abdominal; Arteriosclerosis; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Chickens; Polycyclic Compounds; Tetradecanoylphorbol Acetate | 1981 |
A clinically relevant canine lung cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Delayed-Action Preparations; Disease Models, Animal; Dogs; Lung Neoplasms; Methods; Methylcholanthrene; Methylnitrosourea; Neoplasms, Experimental; Radioisotopes; Tetradecanoylphorbol Acetate | 1981 |
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; Injections, Intraperitoneal; Methylcholanthrene; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Relationship of benign papillomas to cancer induction in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Dose-Response Relationship, Drug; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrans; Benzopyrenes; Carcinogens; Chlorogenic Acid; Cinnamates; Coumaric Acids; Ellagic Acid; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Murine susceptibility to two-stage skin carcinogenesis is influenced by the agent used for promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Cell Line; Cricetinae; Cricetulus; Female; Lung; Mice; Mice, Inbred Strains; Mutagenicity Tests; Mutagens; Mutation; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1984 |
Carcinogen-induced phenotypic alterations in mammary epithelial cells accompanying the development of neoplastic transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Epithelium; Female; Mammary Glands, Animal; Phenotype; Rats; Rats, Inbred Strains; Tamoxifen; Tetradecanoylphorbol Acetate | 1983 |
Ribosomal RNA synthesis and growth in mouse epidermis following initiation with dimethylbenzanthracene and promotion with 12-0-tetradecanoyl-phorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Division; Female; Kinetics; Mice; Organ Size; Phorbols; RNA, Ribosomal; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1983 |
Effect of the promoter 12-O-tetradecanoylphorbol-13-acetate on the evolution of carcinogen-altered cell populations in tracheas initiated with 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Division; Female; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Tracheal Neoplasms | 1983 |
Nature of the epidermal hyperplasia produced by mezerein, a weak tumor promoter, in initiated skin of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diterpenes; Female; Hyperplasia; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Skin painting studies in Syrian hamsters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; Dose-Response Relationship, Drug; Female; Male; Melanoma; Mesocricetus; Neoplasms, Experimental; Nicotiana; Papilloma; Plants, Toxic; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Inhibition of 7-bromomethylbenz[a]anthracene-promoted mouse skin tumor formation by retinoic acid and dexamethasone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Dexamethasone; Drug Interactions; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
On the persistence of tumor initiation in two-stage carcinogenesis on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Cell Transformation, Neoplastic; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Transplacental skin tumor initiation of Ha/ICR mice at different fetal ages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fetus; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
Tumor promotion studies in rat tracheal epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cells, Cultured; Cocarcinogenesis; Epithelium; Methylnitronitrosoguanidine; Neoplasms, Experimental; Organ Culture Techniques; Rats; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms | 1983 |
Monooxygenase activity of human epithelial cells (HeLa): comparison of the response to treatment by arylhydrocarbons and diterpene esters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Dimethyl Sulfoxide; Diterpenes; HeLa Cells; Humans; Polycyclic Compounds; Tetradecanoylphorbol Acetate | 1983 |
Inhibition of the promotion phase in two-step carcinogenesis in forestomach epithelium of mice by the aromatic retinoid etretinate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Epithelium; Etretinate; Female; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Skin tumor formation in the European hamster (Cricetus cricetus L.) after topical initiation with 7,12-dimethylbenz[a]anthracene (DMBA) and promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cricetinae; Drug Synergism; Female; Male; Neoplasms; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1984 |
A two-stage mouse skin carcinogenesis study of lyngbyatoxin A.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Dermotoxins; Lyngbya Toxins; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1984 |
Suppression of the first stage of phorbol 12-tetradecanoate 13-acetate-effected tumor promotion in mouse skin by nontoxic inhibition of DNA synthesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; DNA Replication; Female; Hydroxyurea; Mice; Mice, Inbred Strains; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1984 |
DBA/2 mice are as sensitive as SENCAR mice to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; DNA; Female; Methylnitronitrosoguanidine; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Phorbols; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1984 |
Studies on the promoting and complete carcinogenic activities of some oxidizing chemicals in skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Bromates; Chlorides; Female; Hydrogen Peroxide; Mice; Oxidation-Reduction; Skin Neoplasms; Sodium Hypochlorite; Tetradecanoylphorbol Acetate | 1984 |
Studies on the action of tumour promoters and antipromoters on respiratory-tract epithelium.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Epithelium; Humans; Methylnitronitrosoguanidine; Mice; Rats; Respiratory Tract Neoplasms; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms | 1984 |
Stages of tumour promotion in skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Aging; Animals; Animals, Newborn; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Hyperplasia; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wounds and Injuries | 1984 |
Interaction of phorbol derivatives with replicating cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Cell Cycle; Cell Division; HeLa Cells; Humans; Hydroxyurea; Kinetics; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
On the role of tumour promotion in chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dexamethasone; DNA Replication; Hyperplasia; Indomethacin; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Two-stage tumorigenesis of dermal melanocytes in the back skin of the Syrian golden hamster using systemic initiation with 7,12-dimethylbenz(a)anthracene and topical promotion with 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Cricetinae; Female; Melanocytes; Melanoma; Mesocricetus; Neoplasms, Experimental; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Positive two-stage carcinogenesis in female Sprague-Dawley rats using 7,12-dimethylbenz(a)anthracene (dmba) as initiator and 12-o-tetradecanoylphorbol-13-acetate (tps) as promotor. Results of a pilot study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benz(a)Anthracenes; Castration; Cocarcinogenesis; Colonic Neoplasms; Female; Intestinal Neoplasms; Liver Neoplasms; Phorbols; Rats; Skin Neoplasms; Stomach; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Characteristics of neoplastic progression and tumor behavior in skin carcinogenesis by different methods: an experimental study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Keratoacanthoma; Mice; Neoplasms, Experimental; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1980 |
Autoantibody and tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibody Formation; Autoantibodies; Croton Oil; Female; Mice; Mice, Inbred A; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
Studies on mechanism of action of anti-tumor-promoting agents: their specificity in two-stage promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Diterpenes; Epidermal Cells; Female; Fluocinolone Acetonide; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1980 |
Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chemical Phenomena; Chemistry; Cocarcinogenesis; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1980 |
Promotion-like enhancement of tracheal carcinogenesis in rats by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Dose-Response Relationship, Drug; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Tracheal Neoplasms | 1980 |
Protection of mice against 7,12-dimethylbenz(a)anthracene-induced skin tumors by immunization with a fluorinated analog of the carcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibody Formation; Benz(a)Anthracenes; Cocarcinogenesis; Immunization; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Properties of cell lots suitable for focus assay in the chemical transformation of Syrian hamster cells in culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Drug Evaluation, Preclinical; Mesocricetus; Tetradecanoylphorbol Acetate | 1980 |
Two-stage skin carcinogenesis by systemic initiation of pregnant mice with 7,12-dimethylbenz(a)anthracene during gestation days 6-20 and postnatal promotion of the F 1-generation with the phorbol ester 12-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Fetus; Gestational Age; Mice; Phorbols; Pregnancy; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
The influence of retinoids on polyamine and DNA synthesis in mouse epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; DNA; DNA Replication; Enzyme Induction; Mice; Ornithine Decarboxylase; Polyamines; Skin; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Initiation and promotion at different ages and doses in 2200 mice. I. Methods, and the apparent persistence of initiated cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Initiation and promotion at different ages and doses in 2200 mice. II. Decrease in promotion by TPA with ageing.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Initiation and promotion at different ages and doses in 2200 mice. III. Linear extrapolation from high doses may underestimate low-dose tumour risks.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Risk; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Mouse skin cells resistant to terminal differentiation associated with initiation of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Epidermis; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Skin tumor-promoting activity of benzoyl peroxide, a widely used free radical-generating compound.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Cocarcinogenesis; Free Radicals; Mice; Neoplasms, Experimental; Peroxides; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
The nature of the epidermal growth produced by the first application of 12-0-tetradecanoyl-phorbol-13-acetate on the skin of mice initiated with dimethylbenzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Epidermis; Female; Hyperplasia; Mice; Mitosis; Organ Size; Phorbols; Proteins; Tetradecanoylphorbol Acetate | 1981 |
Diaplacental initiation of NMRI mice with 7,12-dimethylbenz[a]anthracene during gestation days 6--20 and postnatal treatment of the F1-generation with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate: tumor incidence in organs other than the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Female; Gestational Age; Mice; Neoplasms, Experimental; Phorbols; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors; Tetradecanoylphorbol Acetate | 1981 |
Sensitivity to two-stage carcinogenesis of SENCAR mouse skin grafted to nude mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Skin Transplantation; Species Specificity; Tetradecanoylphorbol Acetate | 1982 |
Different effects of dimethylbenz(alpha)anthracene and tetradecanoylphorbol acetate on differentiation of mast cells in the skin of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Bone Marrow Transplantation; Cell Differentiation; Cell Division; Chimera; Female; Male; Mast Cells; Mice; Mice, Inbred C57BL; Phorbols; Skin; Tetradecanoylphorbol Acetate; X-Rays | 1982 |
The differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the initiation-promotion protocol and by the complete carcinogenesis process.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzoflavones; Carcinogens; Cocarcinogenesis; Enzyme Induction; Flavonoids; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 1982 |
Epidermal tumor promotion by regeneration.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Division; Epidermis; Female; Hyperplasia; Mice; Neoplasms, Experimental; Regeneration; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Diterpene ester-mediated two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Cricetinae; Female; Guinea Pigs; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Milk; Neoplasms, Experimental; Phorbols; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vaginal Neoplasms | 1982 |
Epidermal-dermal junction during experimental skin carcinogenesis and cocarcinogenesis as revealed by scanning electron microscopy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Female; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Correlation between sensitivity to tumor promotion and sustained epidermal hyperplasia of mice and rats treated with 12-O-tetra-decanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Hyperplasia; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Phorbols; Rats; Rats, Inbred F344; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1982 |
Mouse skin tumor-initiating activity of 5-, 7-, and 12-methyl- and fluorine-substituted benz[a]anthracenes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Cocarcinogenesis; Female; Hydrocarbons, Fluorinated; Mice; Neoplasms, Experimental; Papilloma; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
7,12-Dimethylbenz[a]anthracene/12-O-tetradecanoyl-phorbol-13-acetate-mediated skin tumor initiation and promotion in male Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Cocarcinogenesis; Diazonium Compounds; Male; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
Effect of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and its nonpromoting analogue 4-O-methyl-TPA on dorsal dermal melanocytes of the Syrian golden hamster (Mesocricetus auratus).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cricetinae; Female; Melanocytes; Melanoma; Mesocricetus; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Stimulation of fibronectin production by retinoic acid in mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromatography, Affinity; Female; Fibronectins; Fucose; Leucine; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Teleocidin from Streptomyces is a potent promoter of mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Carcinogens; Female; Lyngbya Toxins; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Skin Neoplasms; Streptomyces; Tetradecanoylphorbol Acetate | 1982 |
Alkane-6,8-diol: inhibitor of tumor promotion in two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Fatty Alcohols; Female; Mice; Mice, Inbred ICR; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Changes in cytokeratins following treatment of hamster cheek pouch epithelia with hyperplastic or neoplastic agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkynes; Animals; Cricetinae; Diterpenes; Epithelium; Gene Expression Regulation, Neoplastic; Hyperplasia; Immunoblotting; Immunohistochemistry; Keratins; Male; Molecular Weight; Mouth Mucosa; Mouth Neoplasms; Precancerous Conditions; Retinyl Esters; Tetradecanoylphorbol Acetate; Turpentine; Vitamin A | 1994 |
SENCAR mouse skin tumors produced by promotion alone have A to G mutations in codon 61 of the c-rasHa gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Base Sequence; Cocarcinogenesis; Codon; Cytosine; DNA, Neoplasm; Exons; Female; Genes, ras; Mice; Mice, Inbred SENCAR; Mice, Nude; Molecular Sequence Data; Mutation; Nucleic Acid Hybridization; Papilloma; Polymerase Chain Reaction; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Mouse skin tumor progression results in differential expression of retinoic acid and retinoid X receptors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cell Compartmentation; Epidermis; In Situ Hybridization; Keratins; Mice; Papilloma; Receptors, Retinoic Acid; Retinoid X Receptors; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors | 1995 |
Anti-tumor-promoting activities of euglobals from Eucalyptus plants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Burkitt Lymphoma; Cell Cycle; Cocarcinogenesis; Drug Screening Assays, Antitumor; Eucalyptus; Female; Mice; Mice, Inbred ICR; Papilloma; Plant Extracts; Plants, Medicinal; Skin Neoplasms; Structure-Activity Relationship; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Lack of effect of retinoic acid and fluocinolone acetonide on mirex tumor promotion indicates a novel mirex mechanism.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Base Sequence; Carcinogens; Cell Division; Drug Interactions; Ear, External; Edema; Female; Fluocinolone Acetonide; Genes, ras; Genotype; Mice; Mice, Inbred Strains; Mirex; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1995 |
7,12-dimethylbenz[a]anthracene induces oxidative DNA modification in vivo.
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Carcinogens; DNA; DNA Damage; Female; Guanine; Hydrogen Peroxide; Mice; Mice, Inbred SENCAR; Neutrophils; Oxidation-Reduction; Peroxidase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymidine | 1995 |
Collagenase expression in transgenic mouse skin causes hyperkeratosis and acanthosis and increases susceptibility to tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acanthosis Nigricans; Animals; Carcinogenicity Tests; Collagenases; Disease Susceptibility; Epidermis; Haptoglobins; Humans; Hyperplasia; Keratosis; Mice; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
12-Lipoxygenase isoenzymes in mouse skin tumor development.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Arachidonate 12-Lipoxygenase; Base Sequence; Blood Platelets; Cloning, Molecular; Cytosol; DNA, Complementary; Epidermis; Female; Gene Expression Regulation, Neoplastic; Hydroxyeicosatetraenoic Acids; Isoenzymes; Leukocytes; Mice; Molecular Sequence Data; RNA, Neoplasm; Skin Neoplasms; Stereoisomerism; Tetradecanoylphorbol Acetate | 1995 |
Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarboxylase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cell Differentiation; Cells, Cultured; Female; Gene Expression Regulation, Enzymologic; HL-60 Cells; Humans; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Organ Culture Techniques; Ornithine Decarboxylase; Precancerous Conditions; Protein Kinase C; RNA, Messenger; Rotenone; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Cholesterol sulfate, a second messenger for the eta isoform of protein kinase C, inhibits promotional phase in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Cholesterol Esters; Enzyme Activation; Enzyme Induction; Female; Hyperplasia; Isoenzymes; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Second Messenger Systems; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cell Line; Cell Transformation, Neoplastic; Coumaric Acids; Curcumin; Diarylheptanoids; Dose-Response Relationship, Drug; Enzyme Induction; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Studies on the tumor initiation/promotion potential of six middle distillates (MDs) in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Carcinogenicity Tests; Carcinogens; Male; Mice; Mice, Inbred ICR; Mutagenesis; Mutagens; Petroleum; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Sapintoxin D is a weak tumour promoter in Sencar mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Mice; Mice, Inbred SENCAR; Microscopy, Fluorescence; Papilloma; Phorbol Esters; Random Allocation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in TG.AC transgenic mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Composition; Base Sequence; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Cocarcinogenesis; Diglycerides; Female; Fibrosarcoma; Genes, p53; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Anti-tumor-promoting action of FK506, a potent immunosuppressive agent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dermatitis, Contact; Enzyme Induction; Female; Mice; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phosphorylation; Skin Neoplasms; Tacrolimus; Tetradecanoylphorbol Acetate | 1993 |
Morphological changes of the nucleolar organizer regions induced by 7,12-dimethylbenz[a]anthracene in the hamster cheek pouch.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Cheek; Cricetinae; Hyperplasia; Male; Mesocricetus; Mouth Mucosa; Mouth Neoplasms; Nucleolus Organizer Region; Precancerous Conditions; Staining and Labeling; Tetradecanoylphorbol Acetate | 1993 |
Promotion of skin tumors by 12-O-tetradecanoylphorbol-13-acetate in two generations of descendants of male mice exposed to X-ray irradiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Fetus; Genes, ras; Male; Mice; Mutation; Neoplasms, Radiation-Induced; Papilloma; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate; Whole-Body Irradiation; X-Rays | 1993 |
Abrogation of afferent lymph dendritic cell function after cutaneously applied chemical carcinogens.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antigen Presentation; Benzo(a)pyrene; Carcinogens; Cell Movement; Dendritic Cells; Flow Cytometry; Lymphatic System; Lymphocyte Activation; Ovalbumin; Sheep; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1995 |
Role of ornithine decarboxylase in epidermal tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Bromodeoxyuridine; Cell Line; Cells, Cultured; Fibroblasts; Genetic Vectors; Keratinocytes; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Papilloma; Polyamines; Recombinant Proteins; Retroviridae; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate; Transfection | 1995 |
Inhibitors of skin-tumor promotion. XIII. Inhibitory effects of euglobals and their related compounds on Epstein-Barr virus activation and on two-stage carcinogenesis of mouse skin tumors. (2).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Transformed; Female; Herpesvirus 4, Human; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Papilloma; Phloroglucinol; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1995 |
Carcinoma formation in NMRI mouse skin painting studies is a process suggesting greater than two stages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Carcinogenicity Tests; Disease Models, Animal; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Malignant progression of papillomas induced by the initiation--promotion protocol in NMRI mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Disease Models, Animal; Disease Progression; Female; Mice; Mice, Inbred Strains; Models, Statistical; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Effects of methoxychlor on skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Enzyme Induction; Epidermis; Female; Methoxychlor; Mice; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Antioxidant and antipromotional effects of the soybean isoflavone genistein.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Cell Differentiation; Female; Flavonoids; Gene Expression; Genistein; Glycine max; Humans; Hydrogen Peroxide; Intestine, Small; Isoflavones; Mice; Proto-Oncogene Mas; Proto-Oncogenes; RNA, Messenger; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Xanthine Oxidase | 1995 |
Lack of initiation and promotion potential of deoxynivalenol for skin tumorigenesis in Sencar mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Body Weight; Carcinoma, Squamous Cell; Data Interpretation, Statistical; Female; Hyperplasia; Mice; Organ Size; Papilloma; Random Allocation; Skin; Skin Neoplasms; Spleen; Tetradecanoylphorbol Acetate; Trichothecenes | 1995 |
Induction of different genetic changes by different classes of chemical carcinogens during progression of mouse skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Aberrations; Chromosome Deletion; Genes, ras; Methylnitronitrosoguanidine; Mice; Mutation; Polymorphism, Restriction Fragment Length; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trisomy | 1994 |
Inhibitory effect of topical application of polymerized ferulic acid, a synthetic lignin, on tumor promotion in mouse skin two-stage tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Cocarcinogenesis; Coumaric Acids; Female; Mice; Mice, Inbred ICR; Plants, Medicinal; Polymers; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
A course of very small doses of DMBA, each of them allegedly with no promoting potency, acts with clear synergistic effect as a strong promoter of DMBA-initiated mouse skin carcinogenesis. A comparison of the tumorigenic and carcinogenic effects of DMBA (
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma; Drug Synergism; Mice; Mice, Hairless; Papilloma; Skin Neoplasms; Statistics as Topic; Tetradecanoylphorbol Acetate | 1994 |
Consumption of reduced-energy/low-fat diet or constant-energy/high-fat diet during mezerein treatment inhibited mouse skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Cocarcinogenesis; Diet, Fat-Restricted; Dietary Carbohydrates; Dietary Fats; Diterpenes; Energy Intake; Female; Mice; Mice, Inbred SENCAR; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1994 |
High dietary retinoic acid prevents malignant conversion of skin papillomas induced by a two-stage carcinogenesis protocol in female SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred SENCAR; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1994 |
Genetics of chemical carcinogenesis--II. Papilloma induction and malignant conversion in susceptible (Car-s) and resistant (Car-R) lines of mice produced by bidirectional selective breeding and in their (Car-S X Car-R) F1 hybrids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hybridization, Genetic; Male; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Cytogenetic analysis of malignant skin tumors induced in chemically treated TG-AC transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene; Carcinoma, Squamous Cell; Female; Gene Expression; Genes, ras; Karyotyping; Male; Mice; Mice, Transgenic; Neoplasm Transplantation; Papilloma; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Selective down-regulation of protein kinase c-epsilon by carcinogens does not prevent stimulation of phospholipase D by phorbol ester and platelet-derived growth factor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Benzo(a)pyrene; Carcinogens; Cell Line; Isoenzymes; Mice; Mice, Inbred C3H; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Platelet-Derived Growth Factor; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
The use of cell proliferation data in modeling of skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cocarcinogenesis; Kinetics; Likelihood Functions; Mice; Models, Biological; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Minimal role of enhanced cell proliferation in skin tumor promotion by mirex: a nonphorbol ester-type promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Carcinogens; Cell Division; Cocarcinogenesis; Drug Synergism; Female; Hyperplasia; Mice; Mirex; Rats; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Inhibitory effect of karounidiol on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cocarcinogenesis; Female; Inflammation; Mice; Mice, Inbred ICR; Oleanolic Acid; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 1994 |
Tumour-promoting activity of ninhydrin on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Diterpenes; Female; Mice; Ninhydrin; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1994 |
Comparison of 7,12-dimethylbenz(a)anthracene-DNA adduction in the epidermis of two lines of mice selected for resistance (CAR-R) or susceptibility (CAR-S) to skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line; DNA; DNA Adducts; Drug Resistance; Epidermis; Female; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
The absence of a synergistic protective effect of beta-carotene and vitamin E on skin tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; beta Carotene; Carotenoids; Diet; Drug Synergism; Mice; Mice, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Vitamin E | 1993 |
beta-Carotene inhibition of chemically induced toxicity in vivo and in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animal Feed; Animals; beta Carotene; Carotenoids; Cell Line; Diet; Fibroblasts; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Granulocyte-macrophage colony stimulating factor gene expression and function during tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies; Base Sequence; Chemotactic Factors; Female; Gene Expression; Granulocyte-Macrophage Colony-Stimulating Factor; Hydrogen Peroxide; Immunochemistry; Mice; Molecular Sequence Data; Neutrophils; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1994 |
Inhibition of two-stage skin carcinogenesis as well as complete skin carcinogenesis by oral administration of TMK688, a potent lipoxygenase inhibitor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Anticarcinogenic Agents; Arachidonate Lipoxygenases; Benzo(a)pyrene; Female; Indomethacin; Lipoxygenase Inhibitors; Mice; Mice, Inbred Strains; Piperidines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
[Anti-tumor promoting activities of kampo prescriptions. II. Inhibitory effects of souseiryu-to on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Cell Cycle; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred ICR; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
Skin-tumour-promoting activity of processed bidi tobacco in hairless S/RV Cri-ba mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Cocarcinogenesis; Female; Mice; Mice, Mutant Strains; Nicotiana; Occupational Exposure; Papilloma; Plant Extracts; Plants, Toxic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Protection against malignant conversion of chemically induced benign skin papillomas to squamous cell carcinomas in SENCAR mice by a polyphenolic fraction isolated from green tea.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinoma, Squamous Cell; Female; Mice; Nitroquinolines; Papilloma; Plant Extracts; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1993 |
Characterization of benzo[a]pyrene-initiated mouse skin papillomas for Ha-ras mutations and protein kinase C levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Base Sequence; Benzo(a)pyrene; Codon; DNA, Neoplasm; Epidermis; Female; Genes, ras; Isoenzymes; Mice; Mice, Inbred Strains; Molecular Sequence Data; Oligodeoxyribonucleotides; Papilloma; Point Mutation; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Induction of micronuclei and karyotype aberrations during in vivo mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Aberrations; Drug Administration Schedule; Drug Interactions; Karyotyping; Male; Methyl Methanesulfonate; Mice; Mice, Inbred Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Cell; Drug Resistance; Female; Genetic Predisposition to Disease; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1993 |
The reverse experiment in two-stage skin carcinogenesis. It cannot be genuinely performed, but when approximated, it is not innocuous.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Cycle; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Female; Glutathione; Male; Mice; Mice, Hairless; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Anti-tumor promoting activities of natural products. II. Inhibitory effects of digitoxin on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Digitoxin; Female; Glycerol; Lung Neoplasms; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Moderate enhancement of the promotion phase of skin tumorigenesis in hairless mice by topical pretreatment with a mitosis-inhibiting epidermal pentapeptide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Amino Acid Sequence; Animals; Carcinogens; Mice; Mice, Hairless; Mitosis; Molecular Sequence Data; Oligopeptides; Papilloma; Pyrrolidonecarboxylic Acid; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Diacylglycerol is an effector of the clonal expansion of cells containing activated Ha-ras genes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenine; Animals; Base Sequence; Clone Cells; Decanoic Acids; Diglycerides; Genes, ras; Mice; Mice, Transgenic; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Papilloma; Second Messenger Systems; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymine | 1993 |
Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abietanes; Animals; Anticarcinogenic Agents; Antioxidants; Arachidonic Acid; Benzo(a)pyrene; Dermatitis, Contact; DNA; Drug Interactions; Enzyme Induction; Epidermis; Female; Hyperplasia; Magnoliopsida; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Phenanthrenes; Plant Extracts; Skin; Skin Neoplasms; Spices; Tetradecanoylphorbol Acetate; Triterpenes; Tritium; Ursolic Acid | 1994 |
Intermittent 50 Hz magnetic field and skin tumor promotion in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Female; Hyperplasia; Magnetics; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1994 |
DNA adducts, cell proliferation and papilloma latency time in mouse skin after repeated dermal application of DMBA and TPA.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Cell Division; DNA Damage; Female; Mice; Papilloma; Risk Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Studies on inhibitors of skin tumor promotion, XII. Rotenoids from Amorpha fruticosa.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Drug Screening Assays, Antitumor; Flow Cytometry; Hexanes; Methanol; Mice; Plant Extracts; Rotenone; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Lack of initiating capacity of the genotoxic air pollutant 2-nitrofluorene in the mouse skin two-stage carcinogenesis system.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Air Pollutants; Animals; Cocarcinogenesis; Female; Fluorenes; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Southern; Carcinoma; DNA; Genes, p53; Genes, ras; Genotype; Heterozygote; Humans; Male; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Inhibitory effects of 3'-methyl-3-hydroxy-chalcone on proliferation of human malignant tumor cells and on skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Chalcone; Chalcones; Dose-Response Relationship, Drug; HeLa Cells; Humans; Mice; Neoplasm Proteins; Neoplasms; Papilloma; Phosphorylation; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
Inhibitory effects of triptogelin A-1 on 12-O-tetradecanoylphorbol-13- acetate-induced skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Bridged Bicyclo Compounds; Female; Herpesvirus 4, Human; Mice; Mice, Inbred ICR; Sesquiterpenes; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
The suprabasal expression of alpha 6 beta 4 integrin is associated with a high risk for malignant progression in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Biomarkers, Tumor; Diterpenes; Female; Immunohistochemistry; Integrin alpha6beta4; Kinetics; Mice; Mice, Inbred Strains; Papilloma; Risk Factors; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Further studies on the influence of initiation dose on papilloma growth and progression during two-stage carcinogenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; Carcinoma, Squamous Cell; Diterpenes; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Interaction between bovine papillomavirus type 4 and cocarcinogens in the production of malignant tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bovine papillomavirus 1; Bovine papillomavirus 4; Carcinogens; Cattle; Cocarcinogenesis; Female; Mice; Mice, Nude; Papilloma; Tetradecanoylphorbol Acetate | 1993 |
Inhibition of skin tumor promotion by restriction of fat and carbohydrate calories in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinoma; Cocarcinogenesis; Dietary Carbohydrates; Dietary Fats; Disease Models, Animal; Dose-Response Relationship, Drug; Energy Intake; Female; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Absence of synergistic effects on tumor promotion in CD-1 mouse skin by simultaneous applications of two different types of tumor promoters, okadaic acid and teleocidin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Drug Synergism; Enzyme Induction; Ethers, Cyclic; Female; Lyngbya Toxins; Mice; Okadaic Acid; Ornithine Decarboxylase; Phosphorylation; Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
12-O-tetradecanoylphorbol-13-acetate-mediated systemic co-promotion in the murine skin multistage carcinogenesis protocol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Female; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
A study on skin tumour formation in mice with 50 Hz magnetic field exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Electromagnetic Fields; Female; Hyperplasia; Mice; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Vitamin E is a complete tumor promoter in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma; Cocarcinogenesis; Diterpenes; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Vitamin E | 1993 |
Differential effects of dietary beta-carotene on papilloma and carcinoma formation induced by an initiation-promotion protocol in SENCAR mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carcinoma; Carotenoids; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Incidence; Male; Mice; Neoplasms, Multiple Primary; Papilloma; Pregnancy; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Comparison of 12-O-tetradecanoylphorbol-13-acetate and teleocidin for induction of epidermal hyperplasia, activation of epidermal PKC isozymes and skin tumor promotion in SENCAR and C57BL/6 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Enzyme Activation; Female; Hyperplasia; Isoenzymes; Lyngbya Toxins; Mice; Mice, Inbred C57BL; Protein Kinase C; Skin; Tetradecanoylphorbol Acetate | 1993 |
Nonpromoting 12-deoxyphorbol 13-esters inhibit phorbol 12-myristate 13-acetate induced tumor promotion in CD-1 mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Mice; Papilloma; Phorbol Esters; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1993 |
Effects of sodium saccharin and linoleic acid on mRNA levels of Her2/neu and p53 in a human breast epithelial cell line.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Breast; Carcinogens; Cell Line; Dose-Response Relationship, Drug; Epithelium; Gene Expression; Genes, erbB-2; Genes, p53; Humans; Linoleic Acid; Linoleic Acids; Methylnitrosourea; Receptor, ErbB-2; RNA, Messenger; Saccharin; Sweetening Agents; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1996 |
Cellular induction mechanism of CD8+ suppressor T cells by DMBA and TPA: formation of CD4+ suppressor-inducer T cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Hypersensitivity, Delayed; Immunity, Cellular; Interferon-gamma; Lymphocyte Activation; Lymphokines; Macrophages; Male; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Th1 Cells | 1996 |
The inhibition of DMBA-induced carcinogenesis by neoxanthin in hamster buccal pouch.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carotenoids; Cell Division; Cheek; Chemoprevention; Cricetinae; DNA; Enzyme Inhibitors; Facial Neoplasms; Mesocricetus; Ornithine Decarboxylase Inhibitors; Tetradecanoylphorbol Acetate; Xanthophylls | 1995 |
Antitumour activity of protein A in a mouse skin model of two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Anticarcinogenic Agents; Carcinogens; Female; Mice; Skin Neoplasms; Staphylococcal Protein A; Staphylococcus aureus; Survival Analysis; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
The preventive and therapeutic potential of the squalene-containing compound, Roidex, on tumor promotion and regression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aloe; Animals; Carcinogens; Drug Combinations; Drug Screening Assays, Antitumor; Female; Mice; Mineral Oil; Neoplasms, Experimental; Plants, Medicinal; Remission Induction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin A; Vitamin E | 1996 |
The use of initiated cells as a test system for the detection of inhibitors of gap junctional intercellular communication.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aroclors; Benzoyl Peroxide; Biotransformation; Calcium; Carcinogens; Cell Communication; Cell Differentiation; Cell Line; Cyclohexenes; DDT; Intercellular Junctions; Keratinocytes; Limonene; Mice; Phenobarbital; Rats; Terpenes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in mouse skin and the synthesis of DNA, RNA and protein in HeLa cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Caffeic Acids; Carcinogens; DNA; DNA Damage; Female; HeLa Cells; Humans; Mice; Oxidative Stress; Papilloma; Phenylethyl Alcohol; Protein Biosynthesis; RNA; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Dose-time response in mouse skin tumor induction by 7, 12-dimethylbenz[a]anthracene and 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Models, Animal; DNA Adducts; Dose-Response Relationship, Drug; Female; Mice; Papilloma; Random Allocation; Skin Neoplasms; Statistics as Topic; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Carcinogenesis in human skin grafted to SCID mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinogens; Cell Differentiation; Cell Division; Cell Transformation, Neoplastic; Humans; Keratins; Ki-67 Antigen; Mice; Mice, SCID; Neoplasm Proteins; Nuclear Proteins; Papilloma; Skin Neoplasms; Skin Transplantation; Tetradecanoylphorbol Acetate; Transplantation, Heterologous; Ultraviolet Rays | 1996 |
Camptothecin post-treatments inhibit the biochemical events linked to the tumor-promoting component of carcinogenesis in mouse epidermis in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Camptothecin; DNA; DNA Adducts; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Induction; Enzyme Inhibitors; Epidermis; Female; Mice; Ornithine Decarboxylase; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors | 1996 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate promoted mouse skin papilloma by digalactosyl diacylglycerols from the fresh water cyanobacterium Phormidium tenue.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Carbohydrate Sequence; Carcinogenicity Tests; Carcinogens; Cyanobacteria; Female; Galactolipids; Glycolipids; Mice; Mice, Inbred ICR; Molecular Sequence Data; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Characterization of the antitumor-promoting activity of camptothecin in SENCAR mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Diterpenes; DNA Replication; Female; Mice; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors | 1996 |
Regression and progression characteristics of papillomas induced by chrysarobin in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Female; Free Radicals; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
[Inhibition of ornithine decarboxylase activity and epidermal papilloma in mice by beta-carotene].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; beta Carotene; Carotenoids; Female; Mice; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1995 |
Superinduction of mouse epidermal ornithine decarboxylase activity by repeated 12-o-tetradecanoylphorbol-13-acetate treatments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Epidermis; Female; Mice; Molecular Sequence Data; Ornithine Decarboxylase; RNA, Messenger; Tetradecanoylphorbol Acetate | 1996 |
Inhibition of pro-inflammatory cytokine gene expression and papilloma growth during murine multistage carcinogenesis by pentoxifylline.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Division; Female; Gene Expression Regulation, Neoplastic; Inflammation Mediators; Interleukin-1; Mice; Papilloma; Pentoxifylline; Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Dietary retinoic acid inhibits mouse skin carcinogenesis irrespective of age at initiation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aging; Animals; Antineoplastic Agents; Carcinogens; Diet; Diterpenes; Female; Mice; Papilloma; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Tretinoin | 1996 |
Porphyrin-mediated photosensitization has a weak tumor promoting activity in mouse skin: possible role of in situ-generated reactive oxygen species.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dihematoporphyrin Ether; Drug Synergism; Mice; Papilloma; Photosensitizing Agents; Reactive Oxygen Species; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1996 |
Gene expression and cellular sources of inducible nitric oxide synthase during tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; DNA Primers; Enzyme Induction; Female; Keratinocytes; Mice; Mice, Inbred Strains; Models, Biological; Nitric Oxide Synthase; Polymerase Chain Reaction; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tyrosine | 1996 |
Mutagenic potential of peripheral blood leukocytes: in vivo exposure to the carcinogen 7,12-dimethylbenz[a]anthracene, and the tumor promoter 12-O-tetradecanoylphorbol acetate followed by in vitro co-culture with AS52 cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catechin; CHO Cells; Coculture Techniques; Cricetinae; Female; Hypoxanthine Phosphoribosyltransferase; Leukocytes; Mice; Mice, Inbred Strains; Mutagenicity Tests; Mutagens; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 1996 |
Inhibitory effects of sterols isolated from Chlorella vulgaris on 12-0-tetradecanoylphorbol-13-acetate-induced inflammation and tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Extracts; Chlorella; Chromatography; Ergosterol; Female; Inflammation; Mice; Mice, Inbred Strains; Molecular Structure; Skin; Skin Diseases; Sterols; Tetradecanoylphorbol Acetate | 1996 |
Influence of vehicle, distant topical delivery, and biotransformation on the chemopreventive activity of apigenin, a plant flavonoid, in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Topical; Animals; Anticarcinogenic Agents; Biotransformation; Carcinogens; Chamomile; Dimethyl Sulfoxide; Drug Interactions; Enzyme Induction; Female; Flavonoids; Mice; Mice, Inbred SENCAR; Oils, Volatile; Ornithine Decarboxylase; Pharmaceutical Vehicles; Plants, Medicinal; Propylene Glycol; Propylene Glycols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Genetics of chemical carcinogenesis--III. Tissue-specificity of the genes controlling susceptibility and resistance to skin carcinogenesis in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Disease Susceptibility; Female; Immunity, Innate; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Organ Specificity; Sensitivity and Specificity; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory effect of pheophorbide a, a chlorophyll-related compound, on skin tumor promotion in ICR mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Chlorophyll; Drug Screening Assays, Antitumor; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Quantitation of early clonal expansion of two mutant 61st codon c-Ha-ras alleles in DMBA/TPA treated mouse skin by nested PCR/RFLP.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Codon; Female; Genes, ras; Mice; Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Carcinogens; Curcumin; DNA; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Mice; Neoplasms, Experimental; Oxidation-Reduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Susceptibility of 129/SvEv mice in two-stage carcinogenesis protocols to 12-O-tetradecanoylphorbol-13-acetate promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Dermatitis, Contact; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Synergism; Epidermis; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Neutrophils; Papilloma; Peroxidase; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1997 |
The effect of 60-Hz magnetic fields on co-promotion of chemically induced skin tumors on SENCAR mice: a discussion of three studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Electromagnetic Fields; Mice; Mice, Inbred SENCAR; Neoplasms, Radiation-Induced; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Effect of spray-dried yogurt and lactic acid bacteria on the initiation and promotion stages of chemically induced skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bifidobacterium; Body Weight; Carcinogens; Carcinoma; Eating; Energy Intake; Female; Lactobacillus acidophilus; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Yogurt | 1997 |
Effects of capsaicin on chemically-induced two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Capsaicin; Carcinogens; Cocarcinogenesis; Female; Mice; Mice, Inbred ICR; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Enhanced skin carcinogenesis in transgenic mice with high expression of glutathione peroxidase or both glutathione peroxidase and superoxide dismutase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; DNA; Female; Glutathione Peroxidase; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Papilloma; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1997 |
Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle; Cyclin D1; Cyclin D2; Cyclin D3; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Mice; Oncogene Proteins; Papilloma; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Altered glucocorticoid receptor expression and function during mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Fluocinolone Acetonide; Hyperplasia; Keratinocytes; Mice; Mice, Inbred Strains; Papilloma; Receptors, Glucocorticoid; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors | 1997 |
Nitric oxide synthase and skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Deoxyadenosines; Epidermis; Female; Mice; Nitric Oxide Synthase; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1997 |
Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cattle; Cell Division; Cells, Cultured; Cornea; DNA, Antisense; Elasticity; Epidermal Growth Factor; Epidermis; Epithelium; Fibroblast Growth Factor 2; Heparin-binding EGF-like Growth Factor; Hyaluronan Receptors; Hyaluronic Acid; Intercellular Signaling Peptides and Proteins; Keratinocytes; Keratins; Mice; Mice, Transgenic; Promoter Regions, Genetic; Skin; Tetradecanoylphorbol Acetate; Wound Healing | 1997 |
Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Female; Fluocinolone Acetonide; Luciferases; Male; Mice; Mice, Transgenic; Papilloma; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Retinoids; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcriptional Activation; Tretinoin | 1997 |
Failure of carcinogen-altered dendritic cells to initiate T cell proliferation is associated with reduced IL-1 beta secretion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigen Presentation; Benzo(a)pyrene; Carcinogens; Dendritic Cells; Interleukin-1; Lymph; Lymphocyte Activation; Sheep; Skin; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1997 |
Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Age Factors; Animals; Animals, Newborn; Benzo(a)pyrene; Hair Follicle; Immunohistochemistry; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ornithine Decarboxylase; Putrescine; Skin; Skin Neoplasms; Spermidine; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Chemical carcinogens and antigens contribute to cutaneous tumor promotion by depleting epidermal Langerhans cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens; Carcinogens; Carcinoma, Squamous Cell; Female; Langerhans Cells; Mice; Mice, Inbred BALB C; Papilloma; Picryl Chloride; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Inhibitory effect of dietary curcumin on skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Curcumin; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Anti-tumor promoting activities of lantadenes on mouse skin tumors and mouse hepatic tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Diethylnitrosamine; Female; Hyperplasia; Liver Neoplasms; Mice; Mice, Inbred ICR; Oleanolic Acid; Papilloma; Phenobarbital; Plants, Medicinal; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Auraptene, a citrus coumarin, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion in ICR mouse skin, possibly through suppression of superoxide generation in leukocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Citrus; Coumarins; Female; Flow Cytometry; Fluorescent Dyes; Humans; Leukemia, Promyelocytic, Acute; Leukocytes; Mice; Mice, Inbred ICR; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Umbelliferones | 1997 |
Evidence that cutaneous carcinogen-initiated epithelial cells from mice are quiescent rather than actively cycling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antimetabolites, Antineoplastic; Carcinogens; Cell Division; Epidermis; Female; Fluorouracil; Hair Follicle; Mice; Neoplasms, Experimental; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Effect of naturally occurring coumarins on the formation of epidermal DNA adducts and skin tumors induced by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Coumarins; DNA Adducts; Dose-Response Relationship, Drug; Epidermis; Furocoumarins; Mice; Mice, Inbred SENCAR; Skin Neoplasms; Survival Rate; Tetradecanoylphorbol Acetate; Umbelliferones | 1997 |
Atypical association of H1 and H2 histamine receptors with signal transduction pathways during multistage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Count; Cimetidine; Cyclic AMP; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Hydrolysis; Mast Cells; Mice; Phosphatidylinositols; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Second Messenger Systems; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Comparison of chemical carcinogen skin tumor induction efficacy in inbred, mutant, and hybrid strains of mice: morphologic variations of induced tumors and absence of a papillomavirus cocarcinogen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Blotting, Southern; Carcinogens; Cocarcinogenesis; DNA, Viral; Hybridization, Genetic; Mice; Mice, Inbred Strains; Mice, Mutant Strains; Mutation; Papillomaviridae; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Transplantation analyses of the immunogenicity of epidermal tumors generated in murine skin two-stage carcinogenesis protocols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Female; Graft Rejection; Mice; Mice, Inbred SENCAR; Mice, Nude; Neoplasm Transplantation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Evidence that mirex promotes a unique population of epidermal cells that cannot be distinguished by their mutant Ha-ras genotype.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cells, Cultured; Cocarcinogenesis; Female; Genes, ras; Genotype; Immunohistochemistry; Keratinocytes; Mice; Mice, Inbred BALB C; Mirex; Mutation; Nitrosourea Compounds; Papilloma; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Changes in protein expression during multistage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Carcinogens; Connexin 26; Connexins; Cyclin D1; Cyclins; Epidermal Growth Factor; Female; gamma-Glutamyltransferase; Heparin-binding EGF-like Growth Factor; Integrin alpha6beta4; Integrins; Intercellular Signaling Peptides and Proteins; Keratins; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Oncogene Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 1997 |
Evidence that initiated keratinocytes clonally expand into multiple existing hair follicles during papilloma histogenesis in SENCAR mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Clone Cells; Female; Hair Diseases; Hair Follicle; Keratinocytes; Mice; Mice, Inbred SENCAR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Telomerase and cell proliferation in mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Mice; Mice, Inbred Strains; Mitotic Index; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Telomerase; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
Mathematical modeling of skin papilloma data in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Mice; Mice, Inbred SENCAR; Models, Biological; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Differential effects of butyric acid on mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Carcinogens; Female; Histamine Antagonists; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Evaluation of carcinogenic/co-carcinogenic activity of a common chewing product, pan masala, in mouse skin, stomach and esophagus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Areca; Cocarcinogenesis; Esophageal Neoplasms; Female; Male; Mice; Mice, Hairless; Mice, Inbred ICR; Plants, Medicinal; Powders; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Analysis of two inbred strains of mice derived from the SENCAR stock with different susceptibility to skin tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; Biomarkers, Tumor; Carcinogens; Cyclin D1; Disease Susceptibility; Female; Immunohistochemistry; Integrin alpha6beta4; Integrins; Mice; Mice, Inbred Strains; Papilloma; Proliferating Cell Nuclear Antigen; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta | 1998 |
Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Division; DNA Fragmentation; Gene Expression Regulation, Developmental; Genes, bcl-2; Humans; Keratinocytes; Keratins; Mice; Mice, Transgenic; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1998 |
Beta2 integrin/ICAM-1 adhesion molecule interactions in cutaneous inflammation and tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; CD18 Antigens; Cell Division; Dermatitis; Disease Models, Animal; Female; Immunohistochemistry; Intercellular Adhesion Molecule-1; Leukocytes; Mice; Peroxidase; Protein Binding; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Dietary fat and energy modulation of biochemical events in tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cytosol; Dietary Carbohydrates; Dietary Fats; Diglycerides; Energy Metabolism; Isoenzymes; Mice; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1997 |
Phorbol ester stimulation of phosphatidylcholine synthesis requires expression of both protein kinase C-alpha and phospholipase D.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Choline; Choline Kinase; Diglycerides; Enzyme Activation; Female; Humans; Isoenzymes; Mice; Phosphatidylcholines; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1998 |
Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Centrosome; Disease Susceptibility; Epidermis; Female; Gene Amplification; Humans; Keratins; Male; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Papilloma; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras); ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes; Tumor Suppressor Protein p53 | 1998 |
Inhibitory effects of [6]-gingerol, a major pungent principle of ginger, on phorbol ester-induced inflammation, epidermal ornithine decarboxylase activity and skin tumor promotion in ICR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capillary Permeability; Catechols; Curcumin; Epidermis; Fatty Alcohols; Female; Inflammation; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Potent suppressive activity of pheophytin a and b from the non-polyphenolic fraction of green tea (Camellia sinensis) against tumor promotion in mouse skin.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Dose-Response Relationship, Drug; Edema; Female; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Ornithine Decarboxylase; Pheophytins; Skin; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1998 |
Suppression of mouse skin tumor promotion and induction of apoptosis in HL-60 cells by Alpinia oxyphylla Miquel (Zingiberaceae).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogens; DNA Fragmentation; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; HL-60 Cells; Humans; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Phytotherapy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Zingiberales | 1998 |
Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Eflornithine; Genes, ras; Keratoacanthoma; Mice; Mice, Transgenic; Ornithine Decarboxylase; Papilloma; Proliferating Cell Nuclear Antigen; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Isoflavone genistein inhibits the initiation and promotion of two-stage skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; DNA Adducts; Down-Regulation; Drug Screening Assays, Antitumor; Female; Genistein; Hydrogen Peroxide; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Peroxidase; Protein-Tyrosine Kinases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Potent suppressive activity of chlorophyll a and b from green tea (Camellia sinensis) against tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chlorophyll; Chlorophyll A; Edema; Mice; Mice, Inbred BALB C; Pigments, Biological; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate | 1998 |
Squamous cell hyperplastic foci: precursors of cutaneous papillomas induced in SENCAR mice by a two-stage carcinogenesis regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epidermis; Female; Hyperplasia; Mice; Mice, Inbred SENCAR; Neoplasm Regression, Spontaneous; Neoplasm Staging; Papilloma; Precancerous Conditions; Sebaceous Glands; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Influence of diet restriction and tumor promoter dose on cell proliferation, oxidative DNA damage and rate of papilloma appearance in the mouse skin after initiation with DMBA and promotion with TPA.
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Carcinogens; Cell Division; Deoxyguanosine; Diet; DNA; DNA Damage; Immunohistochemistry; Male; Mice; Oxidative Stress; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Anti-tumor-promoting activity of diterpenes from Excoecaria agallocha.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carcinogens; Diterpenes; Euphorbiaceae; Female; Humans; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Virus Activation | 1998 |
Inhibitory effect of Hesperidin on tumour initiation and promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antineoplastic Agents; Carcinogens; Drug Antagonism; Female; Hesperidin; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Inhibitory effect of cycloartenol ferulate, a component of rice bran, on tumor promotion in two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cocarcinogenesis; Dermatitis, Contact; Female; Hypolipidemic Agents; Mice; Mice, Inbred ICR; Oryza; Phenylpropionates; Phytosterols; Plant Extracts; Skin; Skin Neoplasms; Sterols; Tetradecanoylphorbol Acetate; Triterpenes | 1998 |
Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Centrosome; Disease Progression; Endothelial Growth Factors; Genes, p53; Humans; Lymphokines; Mice; Mice, Knockout; Neovascularization, Pathologic; Papilloma; Phenotype; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thrombospondin 1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1998 |
Carcinogenicity and co-carcinogenicity studies on propoxur in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenicity Tests; Carcinogens; Drug Interactions; Female; Insecticides; Male; Mice; Propoxur; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Polyphenols inhibit promotional phase of tumorigenesis: relevance of superoxide radicals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Caffeic Acids; Carcinogens; Coumaric Acids; Diglycerides; Diterpenes; Ellagic Acid; Flavonoids; Glycerol; Hydrolyzable Tannins; Macrophages; Male; Mice; Phenols; Polymers; Polyphenols; Skin Neoplasms; Superoxides; Terpenes; Tetradecanoylphorbol Acetate | 1998 |
Regulation of cytochrome P4501B1 (CYP1B1) in mouse embryo fibroblast (C3H10T1/2) cells by protein kinase C (PKC).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Aryl Hydrocarbon Hydroxylases; Benzophenanthridines; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Enzyme Activation; Enzyme Induction; Gene Expression Regulation; Mice; Mice, Inbred C3H; Phenanthridines; Polychlorinated Dibenzodioxins; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1999 |
MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers; Carcinogens; DNA; Epidermis; Gene Expression; Mice; Mice, Knockout; Mice, Transgenic; Nuclear Proteins; Phenotype; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rabbits; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1999 |
Augmentation of 12-O-tetradecanoyl 13-phorbol acetate-mediated tumor promoting response by the porphyrin photosensitization of 7,12-dimethyl benz[a]anthracene-initiated murine skin: role of in situ generated reactive oxygen species.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Mice; Papilloma; Photosensitivity Disorders; Photosensitizing Agents; Porphyrins; Reactive Oxygen Species; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Inhibition of TPA-induced tumor promotion in CD-1 mouse epidermis by a polyphenolic fraction from grape seeds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthocyanins; Carcinogens; Drug Screening Assays, Antitumor; Eflornithine; Enzyme Inhibitors; Female; Flavonoids; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Peroxidase; Phenols; Polymers; Proanthocyanidins; Rosales; Seeds; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
An antitumor promoter from Moringa oleifera Lam.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents; Carcinogenicity Tests; Carcinogens; Cells, Cultured; Female; Glycosides; Mice; Mice, Inbred ICR; Plant Extracts; Skin; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate | 1999 |
Inhibitory effect of munetone, an isoflavonoid, on 12-O-tetradecanoylphorbol 13-acetate-induced ornithine decarboxylase activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Epidermal Cells; Epidermis; Isoflavones; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Ornithine Decarboxylase Inhibitors; Plant Extracts; Tetradecanoylphorbol Acetate | 1999 |
Genetic deletion of p21WAF1 enhances papilloma formation but not malignant conversion in experimental mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Differentiation; Biomarkers; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Disease Progression; Epidermis; Gene Deletion; Genes, p53; Genotype; Hyperplasia; Mice; Mice, Knockout; Mitotic Index; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1999 |
Altered expression of interleukin-1 receptor antagonist in different stages of mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Carcinoma, Squamous Cell; Cell Polarity; Cytoplasm; Disease Progression; Epidermis; Gene Expression Regulation, Neoplastic; Hyperplasia; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Keratinocytes; Mice; Mice, Inbred SENCAR; Neoplasm Proteins; Papilloma; Precancerous Conditions; RNA, Messenger; RNA, Neoplasm; Sialoglycoproteins; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thapsigargin; Tumor Cells, Cultured | 1999 |
Low antibody responsiveness is found to be associated with resistance to chemical skin tumorigenesis in several lines of Biozzi mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibody Formation; Carcinogenicity Tests; Carcinogens; Disease Susceptibility; Mice; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 1999 |
Chemopreventive effect of 4'-demethyl epipodophyllotoxin on DMBA/TPA-induced mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Catalase; Glutathione; Liver; Male; Malondialdehyde; Mice; Podophyllotoxin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1999 |
Establishment and characterization of normal and initiated hamster tracheal epithelial cell system.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Culture Techniques; Cell Division; Cells, Cultured; Chromosomes; Cloning, Molecular; Cricetinae; Desmosomes; Epithelial Cells; Female; Flow Cytometry; Karyotyping; Keratins; Microscopy, Electron; Pregnancy; Tetradecanoylphorbol Acetate; Trachea | 1999 |
Antitumour promoting activity of indole-3-carbinol in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Female; Indoles; Male; Mice; Skin; Skin Neoplasms; Survival Analysis; Tetradecanoylphorbol Acetate | 1998 |
Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Crosses, Genetic; Female; Immunity, Innate; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neoplasm Invasiveness; Neoplasm Staging; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1999 |
Placental glutathione S-transferase isoenzyme expression during promotion of two-stage hamster cheek-pouch carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cheek; Cricetinae; Glutathione Transferase; Hyperplasia; Immunohistochemistry; Isoenzymes; Male; Mouth Mucosa; Neoplastic Processes; Oropharyngeal Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Potent suppressive effect of a Japanese edible seaweed, Enteromorpha prolifera (Sujiao-nori) on initiation and promotion phases of chemically induced mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carcinogenicity Tests; Carcinogens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred ICR; Pheophytins; Plant Extracts; Seaweed; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
A diacetylenic spiroketal enol ether epoxide, AL-1, from Artemisia lactiflora inhibits 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion possibly by suppression of oxidative stress.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carcinogenicity Tests; Dose-Response Relationship, Drug; Epidermis; Female; Herpesvirus 4, Human; HL-60 Cells; Humans; Hydrogen Peroxide; Intracellular Fluid; Mice; Mice, Inbred ICR; Oxidative Stress; Pyrans; Skin Neoplasms; Spiro Compounds; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation | 1999 |
Anti-carcinogenic activity of Taraxacum plant. I.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Carboxylic Acids; Female; Fumonisins; Humans; Mice; Mice, Inbred ICR; Papilloma; Plant Extracts; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Alterations in ornithine decarboxylase activity in the rat mammary gland after different periods of 50 Hz magnetic field exposure.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cocarcinogenesis; Female; Magnetics; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Melatonin; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1999 |
Anti-tumor promoting activity of polyphenols from Cowania mexicana and Coleogyne ramosissima.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents; Drug Screening Assays, Antitumor; Flavonoids; Herpesvirus 4, Human; Humans; Mice; Mice, Inbred ICR; Papilloma; Phenols; Plant Extracts; Plants, Medicinal; Polymers; Polyphenols; Rosales; Skin Neoplasms; Specific Pathogen-Free Organisms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation | 1999 |
Tumor suppression by p27Kip1 and p21Cip1 during chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinogens; Carcinoma; Cell Cycle Proteins; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Genes, ras; Genes, Tumor Suppressor; Intestinal Neoplasms; Keratinocytes; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mutation; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 1999 |
Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Administration, Cutaneous; Animals; Anticarcinogenic Agents; Antioxidants; Ascorbic Acid; Biflavonoids; Catechin; Cocarcinogenesis; Epidermis; Female; Flavonoids; Lipid Peroxidation; Mice; Mice, Inbred SENCAR; Microsomes; Molecular Structure; Phenols; Plant Extracts; Polymers; Proanthocyanidins; Rosales; Seeds; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin E | 1999 |
Induction of melanoma in TPras transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Albinism; Animals; Carcinoma; Gene Expression Regulation; Genes, ras; Genetic Predisposition to Disease; Hair Color; Hyperplasia; Melanocytes; Melanoma; Mice; Mice, SCID; Mice, Transgenic; Monophenol Monooxygenase; Neoplasm Metastasis; Neoplasms, Radiation-Induced; Papilloma; Promoter Regions, Genetic; Skin Neoplasms; Skin Pigmentation; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 1999 |
Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by TPA, a calcium ionophore and other tumor promoters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calcimycin; Calcium; Carcinogens; Cocarcinogenesis; Diglycerides; Diterpenes; Enzyme Activation; Enzyme Induction; Epidermis; Female; Fluocinolone Acetonide; Gene Expression Regulation; Glutaredoxins; Glutathione; Ionophores; Mice; Oxidation-Reduction; Oxidoreductases; Phorbol Esters; Protein Kinase C; Proteins; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Thioredoxin-Disulfide Reductase; Thioredoxins; Tosylphenylalanyl Chloromethyl Ketone; Tretinoin | 1999 |
A multihit, multistage model of chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Mutational Analysis; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Keratinocytes; Keratins; Mice; Models, Biological; Neoplasm Proteins; Papilloma; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; S Phase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line, Transformed; Female; Genes, ras; Interleukin-1; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Okadaic Acid; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 1999 |
Skin tumorigenesis by initiators and promoters of different chemical structures in lines of mice selectively bred for resistance (Car-r) or susceptibility (Car-s) to two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthracenes; Benzoyl Peroxide; Carcinoma; Methylnitrosourea; Mice; Mice, Inbred Strains; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Protection against 12-O-tetradecanoylphorbol-13-acetate induced skin-hyperplasia and tumor promotion, in a two-stage carcinogenesis mouse model, by the 2,3-dimethyl-6(2-dimethylaminoethyl)-6H-indolo-[2,3-b]quinoxaline analogue of ellipticine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzoyl Peroxide; Carcinogens; Dermatitis, Contact; Female; Hyperplasia; Indoles; Mice; Mice, Inbred SENCAR; Precancerous Conditions; Quinoxalines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Inhibitory effects of chlorophyllin on 7,12-dimethylbenz[a]anthracene-induced bacterial mutagenesis and mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antimutagenic Agents; Chemoprevention; Chlorophyllides; Female; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Sandalwood oil prevent skin tumour development in CD1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Carcinogens; Chemoprevention; Chi-Square Distribution; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Plant Oils; Reference Values; Sesquiterpenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Transgenic mice overexpressing protein kinase Cdelta in the epidermis are resistant to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Humans; Isoenzymes; Keratin-14; Keratins; Keratosis; Male; Mice; Mice, Transgenic; Neoplasm Proteins; Papilloma; Protein Kinase C; Protein Kinase C-delta; Sex Factors; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1999 |
Increased expression of p50-NF-kappaB and constitutive activation of NF-kappaB transcription factors during mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; B-Cell Lymphoma 3 Protein; Carcinogens; Epidermis; Female; Gene Expression Regulation, Neoplastic; I-kappa B Proteins; Mice; Mice, Inbred SENCAR; NF-kappa B; NF-kappa B p50 Subunit; Proto-Oncogene Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor RelA; Transcription Factors | 1999 |
Induction of skin papillomas, carcinomas, and sarcomas in mice in which the connexin 43 gene is heterologously deleted.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Connexin 43; Fibrosarcoma; Gene Deletion; Genes, ras; Mice; Mice, Inbred C57BL; Papilloma; Point Mutation; Sarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Human papillomavirus types 16 E6 and E7 contribute differently to carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Mutation; Oncogene Proteins, Viral; Papilloma; Papillomavirus E7 Proteins; Repressor Proteins; Severity of Illness Index; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Evidence that the epidermal targets of carcinogen action are found in the interfollicular epidermis of infundibulum as well as in the hair follicles.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epidermis; Female; Hair Follicle; Mice; Mice, Inbred SENCAR; Papilloma; Regeneration; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Epidermis; Female; Humans; Isoenzymes; Male; Mice; Mice, Transgenic; Papilloma; Phenotype; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Evaluation of carcinogenic and co-carcinogenic potential Quinalphos in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Alopecia; Animals; Carcinogens; Cocarcinogenesis; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Insecticides; Male; Mice; Organothiophosphorus Compounds; Skin Neoplasms; Skin Ulcer; Tetradecanoylphorbol Acetate | 2000 |
Evidence against a role of general protein kinase C downregulation in skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Isoenzymes; Mice; Mice, Inbred Strains; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Inhibitory effect of euphol, a triterpene alcohol from the roots of Euphorbia kansui, on tumour promotion by 12-O-tetradecanoylphorbol-13-acetate in two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Alcohols; Animals; Antihypertensive Agents; Carcinogens; Ear; Female; Inflammation; Lanosterol; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2000 |
Development and initial characterization of several new inbred strains of SENCAR mice for studies of multistage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Mice; Mice, Inbred SENCAR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Bacteriophage phi X 174; Brain; Carcinogens; DNA, Viral; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; HL-60 Cells; Hot Temperature; Humans; Hydrogen Peroxide; Lipid Peroxidation; Male; Methanol; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Panax; Papilloma; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2000 |
Chemopreventive effects of sage oil on skin papillomas in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Anticarcinogenic Agents; Cell Division; Cell Survival; Injections, Intraperitoneal; Lamiaceae; Lethal Dose 50; Mice; Papilloma; Plant Oils; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2000 |
The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57BL/6 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; DNA Mutational Analysis; Female; Genes, Neurofibromatosis 1; Genes, ras; Humans; Mice; Mice, Inbred C57BL; Papilloma; Skin; Skin Neoplasms; Skin Pigmentation; Tetradecanoylphorbol Acetate | 2000 |
Allelotype analysis of chemically induced squamous cell carcinomas in F(1) hybrids of two inbred mouse strains with different susceptibility to tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogens; Carcinoma, Squamous Cell; Chimera; Crosses, Genetic; Disease Progression; Genetic Predisposition to Disease; Genotype; Humans; Loss of Heterozygosity; Mice; Mice, Inbred SENCAR; Microsatellite Repeats; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Conceptually new deltanoids (vitamin D analogs) inhibit multistage skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Calcitriol; Calcium; Carcinogens; Enzyme Induction; Female; Growth; Mice; Ornithine Decarboxylase; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Vitamin D | 2000 |
Promotion of skin carcinogenesis by dimethylarsinic acid in keratin (K6)/ODC transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cacodylic Acid; Carcinogens; Cocarcinogenesis; Female; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ornithine Decarboxylase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Anti-tumor-promoting activity of lignans from the aerial part of Saussurea medusa.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, Topical; Animals; Antineoplastic Agents, Phytogenic; Asteraceae; Cells, Cultured; Disease Models, Animal; Female; Glycerol; Lignans; Lung Neoplasms; Mice; Mice, Inbred ICR; Mice, Inbred SENCAR; Neoplasm Transplantation; Phytotherapy; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Transformation, Neoplastic; Centrosome; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p27; Epidermal Cells; Gene Expression; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Mitosis; Papilloma; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Tetradecanoylphorbol Acetate; Time Factors; Tumor Suppressor Proteins | 2000 |
Microsatellite DNA variants between the inbred SENCAR mouse strains.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Genetic Markers; Genetic Predisposition to Disease; Genetic Variation; Genotype; Mice; Mice, Inbred SENCAR; Microsatellite Repeats; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 2000 |
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Flow Cytometry; Immunity, Innate; Immunohistochemistry; In Situ Hybridization, Fluorescence; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Papilloma; Proto-Oncogene Proteins p21(ras); Skin; Skin Neoplasms; Telomerase; Telomere; Tetradecanoylphorbol Acetate; Time Factors; Tumor Suppressor Protein p53 | 2000 |
Antitumor-promoting effects of cyclic diarylheptanoids on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Diarylheptanoids; Dose-Response Relationship, Drug; Female; Herpesvirus 4, Human; Humans; Hydrocarbons, Cyclic; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Specific Pathogen-Free Organisms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Virus Activation | 2000 |
A simple phenolic antioxidant protocatechuic acid enhances tumor promotion and oxidative stress in female ICR mouse skin: dose-and timing-dependent enhancement and involvement of bioactivation by tyrosinase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Biotransformation; Carcinogens; Dermatitis, Contact; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Female; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Hydrogen Peroxide; Hydroxybenzoates; Mice; Mice, Inbred ICR; Monophenol Monooxygenase; Oxidative Stress; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Development of spontaneous hyperplastic skin lesions and chemically induced skin papillomas in transgenic mice expressing human papillomavirus type 16 E6/E7 genes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Female; Gene Expression; Humans; Hyperplasia; Mice; Mice, Inbred ICR; Mice, Transgenic; Monophenol Monooxygenase; Oncogene Proteins, Viral; Papilloma; Papillomaviridae; Papillomavirus E7 Proteins; Pregnancy; Repressor Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Genetics of chemical carcinogenesis: analysis of bidirectional selective breeding inducing maximal resistance or maximal susceptibility to 2-stage skin tumorigenesis in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Genetic Predisposition to Disease; Hair Color; Male; Mice; Mice, Inbred Strains; Quantitative Trait, Heritable; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate | 2000 |
Kurosu, a traditional vinegar produced from unpolished rice, suppresses lipid peroxidation in vitro and in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetic Acid; Animals; Antioxidants; Bepridil; Biphenyl Compounds; Edema; Female; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Inflammation; Lipid Peroxidation; Mice; Mice, Inbred ICR; Oryza; Picrates; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiobarbituric Acid Reactive Substances; Time Factors; Vitamin E | 2000 |
Cancer chemopreventive agents, labdane diterpenoids from the stem bark of Thuja standishii (Gord.) Carr.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; beta Carotene; Carboxylic Acids; Carcinogens; Diterpenes; Female; Humans; Mice; Mice, Inbred ICR; Naphthalenes; Nasopharyngeal Neoplasms; Neoplasms; Papilloma; Plant Extracts; Plant Stems; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trees | 2000 |
Anti-tumor-promoting effects of glycoglycerolipid analogues on two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents; Biological Assay; Carcinogens; Female; Glycolipids; Lipids; Mice; Mice, Inbred ICR; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Potential carcinogenic and inhibitory activity of compounds isolated from Lilium candidum L.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Ethanol; Liliaceae; Mice; Mutagens; Plant Extracts; Polarography; Pyrroles; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2000 |
Retinoic acid (RA) receptor transcriptional activation correlates with inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase (ODC) activity by retinoids: a potential role for trans-RA-induced ZBP-89 in ODC inhibition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Blotting, Northern; Blotting, Western; Carcinogens; Cell Survival; Collagenases; DNA-Binding Proteins; Dose-Response Relationship, Drug; Epidermis; Epithelial Cells; Female; HeLa Cells; Humans; Mice; Mice, Hairless; Neoplasms, Experimental; Ornithine Decarboxylase Inhibitors; Papilloma; Promoter Regions, Genetic; Protein Binding; Protein Kinases; Rats; Receptors, Retinoic Acid; Response Elements; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Ultraviolet Rays | 2001 |
Cancer chemopreventive activity of 3,5,6,7,8,3',4'-heptamethoxyflavone from the peel of citrus plants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Citrus; Female; Flavones; Flavonoids; Mice; Nitro Compounds; Papilloma; Plant Extracts; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Bax gene disruption alters the epidermal response to ultraviolet irradiation and in vivo induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-2-Associated X Protein; Carcinogens; Cell Differentiation; Epidermal Cells; Epidermis; Genes, bcl-2; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Keratinocytes; Keratins; Membrane Proteins; Mice; Mice, Knockout; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2001 |
Induction of mouse epidermal ornithine decarboxylase activity and skin tumors by 7,12-dimethylben.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; Carcinogens; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Epidermis; Female; Mice; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Protein kinase C-epsilon transgenic mice: a unique model for metastatic squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Disease Progression; Female; Hair Follicle; Isoenzymes; Lymphatic Metastasis; Male; Mice; Mice, Transgenic; Protein Kinase C; Protein Kinase C-epsilon; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Inhibition of carcinogen induced c-Ha-ras and c-fos proto-oncogenes expression by dietary curcumin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Carcinogens; Curcumin; Dose-Response Relationship, Drug; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, fos; Genes, ras; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Cancer prevention by natural carotenoids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; beta Carotene; Carotenoids; Colonic Neoplasms; Cryptoxanthins; Disease Models, Animal; Fruit; Humans; Lutein; Lycopene; Methylnitrosourea; Mice; Rats; Rats, Inbred F344; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vegetables; Xanthophylls; Zeaxanthins | 2000 |
[p53 gene mutations in mouse skin tumors induced by DMBA-TPA-MNNG].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Exons; Genes, p53; Methylnitronitrosoguanidine; Mice; Mice, Inbred SENCAR; Papilloma; Point Mutation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1998 |
Two-stage carcinogenesis in NMRI mice: intravaginal application of 7,12-dimethylbenz[a]anthracene as initiator followed by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Administration, Intravaginal; Animals; Carcinogens; Carcinoma; Cocarcinogenesis; Drug Synergism; Female; Hyperplasia; Leukemia, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Models, Animal; Neoplasms, Experimental; Organ Specificity; Ovarian Neoplasms; Papilloma; Precancerous Conditions; Sarcoma, Experimental; Specific Pathogen-Free Organisms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vagina; Vaginal Neoplasms | 1980 |
Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis by independent mechanisms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Down-Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Keratin-10; Keratins; Melanoma, Experimental; Mice; Mice, Transgenic; Neoplasm Transplantation; Phenotype; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Transgenes; Up-Regulation | 2001 |
Induction of thymidine kinase in mouse skin exposed to 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dose-Response Relationship, Drug; Female; Mice; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Skin; Tetradecanoylphorbol Acetate; Thymidine Kinase; Time Factors | 2001 |
Targeted expression of bcl-2 to murine basal epidermal keratinocytes results in paradoxical retardation of ultraviolet- and chemical-induced tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Genes, ras; Humans; Keratinocytes; Mice; Mice, Transgenic; Mutagenesis; Papilloma; Proto-Oncogene Proteins c-bcl-2; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2001 |
Relation of skin polyamines to the hairless phenotype in transgenic mice overexpressing spermidine/spermine N-acetyltransferase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetyltransferases; Aging; Alopecia; Animals; Animals, Newborn; Carcinogens; Mice; Mice, Transgenic; Neoplasm Staging; Ornithine Decarboxylase; Papilloma; Phenotype; Polyamines; Putrescine; Reference Values; Skin; Skin Neoplasms; Spermidine; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Tumourigenic studies on deltamethrin in Swiss albino mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benzo(a)pyrene; Carcinogenicity Tests; Carcinogens; Cocarcinogenesis; Female; Insecticides; Male; Mice; Nitriles; Pyrethrins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Catalytic Domain; Cattle; DNA-Binding Proteins; Female; Gastric Mucosa; Genes, p53; Genetic Therapy; Hyperplasia; Keratinocytes; Keratins; Mice; Mice, Knockout; Mice, Transgenic; Mouth Mucosa; Neoplasms, Experimental; Papilloma; Protein Subunits; RNA; Skin; Skin Neoplasms; Stomach; Telomerase; Telomere; Tetradecanoylphorbol Acetate; Vagina; Wound Healing | 2001 |
Transplacental carcinogenic potential of the carbamate fungicide mancozeb.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Models, Animal; Female; Fungicides, Industrial; Male; Maneb; Maternal Exposure; Maternal-Fetal Exchange; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Skin Neoplasms; Tetradecanoylphorbol Acetate; Zineb | 2001 |
Induction of CD4+ regulatory T cells by 12-O-tetradecanoylphorbol 13-acetate in mice. Part 1: The strain difference in this induction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Surface; CD4 Antigens; Down-Regulation; Female; Hybridomas; Hypersensitivity, Delayed; Indicators and Reagents; Male; Mice; Mice, Inbred Strains; Species Specificity; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2001 |
Anti-tumor promoting diterpenes from the stem bark of Thuja standishii (Cupressaceae).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Carcinogens; Diterpenes; Female; Mice; Mice, Inbred ICR; Plant Stems; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trees | 2001 |
Influence of beta1 integrins on epidermal squamous cell carcinoma formation in a transgenic mouse model: alpha3beta1, but not alpha2beta1, suppresses malignant conversion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Antigens, Neoplasm; Basigin; Carcinogens; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; Female; Integrin alpha3beta1; Integrins; Keratinocytes; Membrane Glycoproteins; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Papilloma; Receptors, Collagen; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tetraspanin 28 | 2001 |
Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biogenic Polyamines; Carcinogens; Cattle; Enzyme Induction; Enzyme Inhibitors; Keratin-15; Keratin-5; Keratins; Mice; Mice, Transgenic; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Overexpression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signaling in a multistage skin carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Models, Animal; Enzyme Activation; Female; Humans; Isoenzymes; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Oxidative Stress; Protein Kinase C; Protein Kinase C-epsilon; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Signal Transduction; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2001 |
Antioxidative and antitumor promoting effects of [6]-paradol and its homologs.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Carcinogens; DNA Damage; Ear, External; Edema; Epidermis; Female; Guaiacol; Hydrogen Peroxide; Ketones; Mice; Mice, Inbred ICR; Ornithine Decarboxylase; Peroxidase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Cancer chemopreventive agents, serratane-type triterpenoids from Picea jezoensis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Female; Humans; Mice; Mice, Inbred ICR; Papilloma; Plants; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2001 |
Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), suppress H-ras mutations and aneuploidy in a murine skin carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acacia; Aneuploidy; Animals; Dioxoles; Disease Models, Animal; Female; Genes, ras; Humans; Jurkat Cells; Mice; Mice, Inbred SENCAR; Papilloma; Phenanthridines; Phytotherapy; Saponins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2001 |
Lack of effect of 94 GHz radio frequency radiation exposure in an animal model of skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Drug Administration Schedule; Electromagnetic Fields; Female; Incidence; Mice; Mice, Inbred SENCAR; Neoplasms, Radiation-Induced; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Cancer chemopreventive activity of naphthoquinones and their analogs from Avicennia plants.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carcinogens; Female; Humans; In Vitro Techniques; Mice; Mice, Inbred ICR; Naphthoquinones; Papilloma; Plant Extracts; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation | 2001 |
Lack of promotion of 7,12-dimethylbenz[a]anthracene-initiated mouse skin carcinogenesis by 1.5 GHz electromagnetic near fields.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenocorticotropic Hormone; Animals; Carcinogens; Carcinoma, Squamous Cell; Corticosterone; Electromagnetic Fields; Epidermis; Female; Incidence; Melatonin; Mice; Mice, Inbred ICR; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2001 |
Discrete roles of cytokines, TNF-alpha, IL-1, IL-6 in tumor promotion and cell transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA Primers; Female; Humans; Interleukin-1; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Necrosis Factor-alpha | 2002 |
Overexpression of bone morphogenetic protein-6 (BMP-6) in murine epidermis suppresses skin tumor formation by induction of apoptosis and downregulation of fos/jun family members.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Bone Morphogenetic Protein 6; Bone Morphogenetic Proteins; Cell Division; Down-Regulation; Epidermis; Genes, fos; Genes, jun; Immunohistochemistry; In Situ Hybridization; In Situ Nick-End Labeling; Keratinocytes; Mice; Mice, Transgenic; Mutation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Western; Bromodeoxyuridine; Carcinogens; CCAAT-Enhancer-Binding Protein-beta; Cell Division; Cell Survival; Genes, Reporter; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutagens; Mutation; Oncogene Protein p21(ras); Phosphorylation; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcriptional Activation | 2002 |
Interleukin-1alpha up-regulation in vivo by a potent carcinogen 7,12-dimethylbenz(a)anthracene (DMBA) and control of DMBA-induced inflammatory responses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies; Carcinogens; DNA Damage; Edema; Female; Immunoglobulin G; Interleukin-1; Mice; Mice, Inbred SENCAR; Neutrophils; Oxidative Stress; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2002 |
Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetyltransferases; Animals; Animals, Genetically Modified; Carcinogens; Cattle; Genetic Predisposition to Disease; Immunohistochemistry; Keratinocytes; Keratins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Plasmids; Promoter Regions, Genetic; Putrescine; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Magnetic field exposure increases cell proliferation but does not affect melatonin levels in the mammary gland of female Sprague Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bromodeoxyuridine; Cell Division; Female; Ki-67 Antigen; Magnetics; Mammary Glands, Animal; Melatonin; Pineal Gland; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2002 |
Antitumor activity of compounds isolated from leaves of Eriobotrya japonica.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents; Biflavonoids; Carcinogens; Catechin; Female; Glucosides; Herpesvirus 4, Human; Humans; Mice; Mice, Inbred ICR; Nasopharyngeal Neoplasms; Norisoprenoids; Peroxynitrous Acid; Plant Leaves; Proanthocyanidins; Rosaceae; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Virus Activation | 2002 |
Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alopecia; Animals; Carcinogens; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Hair Follicle; Humans; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Mice, Transgenic; Phenotype; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Skin; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate | 2002 |
A comparison of the anticarcinogenic properties of four red wine polyphenols.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Catechin; Flavonoids; Gallic Acid; Mice; Phenols; Polymers; Quercetin; Resveratrol; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Wine | 2002 |
Cancer chemopreventive effects of a Brazilian folk medicine, Juca, on in vivo two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Brazil; Caesalpinia; Female; Fruit; Gallic Acid; Medicine, Traditional; Mice; Mice, Inbred ICR; Papilloma; Phytotherapy; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2002 |
Protein kinase Cdelta-mediated signal to ornithine decarboxylase induction is independent of skin tumor suppression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Cycle Proteins; Cell Division; Eflornithine; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Epidermis; Female; Isoenzymes; Kinetics; Male; Mice; Mice, Knockout; Mice, Transgenic; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Protein Kinase C; Protein Kinase C-delta; RNA, Messenger; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 2002 |
Chemopreventive effects of emodin and cassiamin B in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthraquinones; Anticarcinogenic Agents; Cassia; Emodin; Enzyme Inhibitors; Female; Mice; Mice, Inbred ICR; Phytotherapy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Death; Cell Differentiation; Cell Division; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; DNA Adducts; Female; Immunohistochemistry; Isoenzymes; Keratinocytes; Membrane Proteins; Mice; Mice, Inbred C57BL; Papilloma; Prostaglandin-Endoperoxide Synthases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2002 |
Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Division; Disease Progression; Gene Dosage; Genotype; Guanine Nucleotide Exchange Factors; Immunohistochemistry; Keratins; Mice; Mice, Knockout; Proteins; ras Proteins; Skin Neoplasms; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Tetradecanoylphorbol Acetate | 2002 |
Tumour necrosis factor-alpha mediates tumour promotion via a PKC alpha- and AP-1-dependent pathway.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epidermal Cells; Epidermis; Isoenzymes; Keratinocytes; Kinetics; Matrix Metalloproteinases; Mice; Mice, Inbred BALB C; Mice, Knockout; Protein Kinase C; Protein Kinase C-alpha; RNA, Messenger; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2002 |
Protection against human papillomavirus type 16-E7 oncogene-induced tumorigenesis by in vivo expression of dominant-negative c-jun.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Genes, Dominant; Genes, jun; Mice; Mice, Transgenic; Neoplasms, Experimental; Oncogene Proteins, Viral; Papillomaviridae; Papillomavirus E7 Proteins; Tetradecanoylphorbol Acetate | 2002 |
The effect of beta-carotene on lung and skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carcinogens; Dose-Response Relationship, Drug; Ferrets; Lung Neoplasms; Mice; Nicotiana; Papilloma; Precancerous Conditions; Skin Neoplasms; Smoke; Tetradecanoylphorbol Acetate | 2002 |
Chemopreventive effect of resveratrol, sesamol, sesame oil and sunflower oil in the Epstein-Barr virus early antigen activation assay and the mouse skin two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Artemia; Benzodioxoles; Biphenyl Compounds; Cocarcinogenesis; Female; Free Radical Scavengers; Herpesvirus 4, Human; Lethal Dose 50; Mice; Mice, Inbred ICR; Phenols; Picrates; Plant Oils; Resveratrol; Sesame Oil; Skin Neoplasms; Stilbenes; Sunflower Oil; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Virus Activation | 2002 |
Modulation of epidermal tumor development caused by targeted overexpression of epidermis-type 12S-lipoxygenase.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 9,10-Dimethyl-1,2-benzanthracene; Animals; Arachidonate 12-Lipoxygenase; Carcinogens; Down-Regulation; Female; Gene Expression; Isoenzymes; Linoleic Acids; Male; Mice; Mice, Inbred DBA; Mice, Transgenic; Papilloma; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2002 |
Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aloe; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Ear; Edema; Female; Mice; Mice, Inbred ICR; Plant Extracts; Plant Leaves; Plants, Medicinal; Putrescine; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2002 |
Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Carcinogens; Carcinoma, Squamous Cell; Celecoxib; Cocarcinogenesis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Gene Expression; Isoenzymes; Mice; Mice, Transgenic; Papilloma; Phenotype; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Skin; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate | 2002 |
Inhibition by ajoene of skin-tumor promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Carcinogens; Disulfides; Garlic; Male; Mice; Mice, Inbred ICR; Plant Extracts; Skin Neoplasms; Solvents; Sulfoxides; Tetradecanoylphorbol Acetate | 2002 |
Progressive iron overload enhances chemically mediated tumor promotion in murine skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Benzoyl Peroxide; Carcinogens; Catalase; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Induction; Enzyme Repression; Glutathione; Iron; Iron Overload; Lipid Peroxidation; Mice; Ornithine Decarboxylase; Oxidative Stress; Papilloma; Reactive Oxygen Species; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2003 |
A 60 Hz magnetic field does not affect the incidence of squamous cell carcinomas in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Back; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Drug Tolerance; Electricity; Electromagnetic Fields; Mice; Mice, Inbred SENCAR; Neoplasms, Radiation-Induced; Radiation Tolerance; Reference Values; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Beta vulgaris; Betacyanins; Body Weight; Carcinogens; Diethylnitrosamine; Dose-Response Relationship, Drug; Female; Hydroxylamines; Indoles; Liver Neoplasms, Experimental; Mice; Mice, Inbred ICR; Neoplasms, Radiation-Induced; Phenobarbital; Plant Extracts; Plant Roots; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2003 |
Circadian rhythm of tumor promotion in the two-stage model of mouse tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Circadian Rhythm; Disease Models, Animal; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2003 |
Survivin expression in mouse skin prevents papilloma regression and promotes chemical-induced tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Female; Immunohistochemistry; Inhibitor of Apoptosis Proteins; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Neoplasm Proteins; Papilloma; Skin; Skin Neoplasms; Survivin; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2003 |
Expression of enhancing factor/phospholipase A2 in skin results in abnormal epidermis and increased sensitivity to chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abnormalities, Multiple; Animals; Carcinogens; Carcinoma, Squamous Cell; Epidermis; Fibrosarcoma; Genetic Predisposition to Disease; Genotype; Group II Phospholipases A2; Humans; Keratins; Mice; Mice, Transgenic; Neoplasms, Basal Cell; Papilloma; Phenotype; Phospholipases A; Promoter Regions, Genetic; Recombinant Fusion Proteins; Skin; Skin Neoplasms; Tail; Tetradecanoylphorbol Acetate; Transgenes; Vibrissae | 2003 |
An anti-tumor necrosis factor-alpha antibody inhibits the development of experimental skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Carcinogens; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Immunity, Innate; Keratinocytes; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Staging; Papilloma; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha | 2003 |
Disruption of protein kinase Ceta results in impairment of wound healing and enhancement of tumor formation in mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Hyperplasia; Mice; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wound Healing | 2003 |
IL-1 alpha, innate immunity, and skin carcinogenesis: the effect of constitutive expression of IL-1 alpha in epidermis on chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; DNA-Binding Proteins; Epidermis; Female; Humans; Immunity, Innate; Interleukin-1; Keratin-14; Keratins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nuclear Proteins; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2003 |
Metallothionein deficiency enhances skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol-13-acetate in metallothionein-null mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Female; Genes, ras; Metallothionein; Mice; Mice, Inbred C57BL; Mutation; Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
The effect of plant phenolics on the formation of 7,12-dimethylbenz[a]anthracene-DNA adducts and TPA-stimulated polymorphonuclear neutrophils chemiluminescence in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chlorogenic Acid; DNA; DNA Adducts; Enzyme Inhibitors; Humans; Hydrolyzable Tannins; Hydroxybenzoates; Luminescent Measurements; Male; Methylcholanthrene; Neutrophils; Phenols; Rats; Rats, Wistar; Reactive Oxygen Species; Respiratory Burst; Resveratrol; Stilbenes; Tetradecanoylphorbol Acetate | 2003 |
Toxicological evaluation of honey as an ingredient added to cigarette tobacco.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Inhalation; Animals; Body Weight; Carcinogenicity Tests; Carcinogens; Female; Honey; In Vitro Techniques; Male; Mutagenicity Tests; Nicotiana; Organ Size; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Sister Chromatid Exchange; Skin Neoplasms; Smoke; Smoking; Tetradecanoylphorbol Acetate | 2003 |
H-ras mutations at codon 61 or 13 in tumors initiated with a NO donor in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Codon; Female; Genes, ras; Mice; Mutation; Nitric Oxide; Nitro Compounds; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenori.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Cells, Cultured; Cocarcinogenesis; Female; Lymphocytes; Mice; Mice, Inbred ICR; Momordica; Peroxynitrous Acid; Skin Neoplasms; Sweetening Agents; Tetradecanoylphorbol Acetate; Triterpenes | 2003 |
Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Carcinoma, Squamous Cell; CSK Tyrosine-Protein Kinase; Female; Male; Mice; Mice, Transgenic; Molecular Sequence Data; Neoplasm Metastasis; Protein-Tyrosine Kinases; Skin; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate | 2003 |
Ichthyotoxic and anticarcinogenic effects of triterpenoids from Sandoricum koetjape bark.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Epstein-Barr Virus Nuclear Antigens; Female; Fundulidae; Meliaceae; Mice; Mice, Inbred ICR; Plant Bark; Plant Extracts; Tetradecanoylphorbol Acetate; Triterpenes | 2003 |
The distinct contributions of murine T cell receptor (TCR)gammadelta+ and TCRalphabeta+ T cells to different stages of chemically induced skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Models, Animal; Hematopoietic Stem Cells; Liver; Mice; Mice, Knockout; Neoplasm Staging; Papilloma; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate; Time Factors | 2003 |
Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Carcinoma; Cells, Cultured; Endoglin; Epidermal Cells; Epidermis; Humans; Keratinocytes; Mice; Mice, Mutant Strains; Neoplasms, Experimental; Papilloma; Receptors, Cell Surface; Reference Values; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Vascular Cell Adhesion Molecule-1 | 2003 |
Absence of tumor promoting activity of Euphorbia milii latex on the mouse back skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Euphorbia; Female; Latex; Male; Mice; Mice, Inbred DBA; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
Chemopreventive effects of pomegranate seed oil on skin tumor development in CD1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Female; Lythraceae; Mice; Mice, Inbred Strains; Plant Oils; Random Allocation; Seeds; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2003 |
Free radical generating agents lead to the rapid progression of benign skin tumors to carcinoma in iron-overloaded mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Benzoyl Peroxide; Carcinogens; Carcinoma, Squamous Cell; Disease Progression; Female; Free Radicals; Hydrogen Peroxide; Iron; Iron Overload; Iron-Dextran Complex; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Electron Spin Resonance Spectroscopy; Genes, Reporter; Hydrogen Peroxide; Hydroxyl Radical; Luciferases; Malus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Phosphorylation; Plant Extracts; Reactive Oxygen Species; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1; Transcriptional Activation; Transgenes; Ultraviolet Rays | 2004 |
Rosmarinic acid inhibits epidermal inflammatory responses: anticarcinogenic effect of Perilla frutescens extract in the murine two-stage skin model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Carcinogens; Cinnamates; Depsides; DNA Primers; Male; Mice; Mice, Inbred BALB C; Perilla frutescens; Phytotherapy; Polymerase Chain Reaction; RNA, Messenger; Rosmarinic Acid; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
E6 and E7 oncoproteins induce distinct patterns of chromosomal aneuploidy in skin tumors from transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aneuploidy; Animals; Carcinogens; Cell Line, Tumor; Chromosome Mapping; Chromosomes; DNA Primers; Genes, p53; Genes, ras; Genes, Retinoblastoma; Karyotyping; Mice; Mice, Transgenic; Mutation; Oncogene Proteins, Viral; Papillomaviridae; Papillomavirus E7 Proteins; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Repressor Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antigens, Viral; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Mice; Mice, Inbred ICR; Otitis; Papilloma; Perilla frutescens; Plant Leaves; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2004 |
Only a subset of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin papillomas are promotable by benzoyl peroxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Carcinogens; Cocarcinogenesis; DNA Primers; Drug Resistance, Neoplasm; Female; Genes, ras; Genetic Predisposition to Disease; Male; Mice; Mutation; Papilloma; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Study on prevention of two-stage skin carcinogenesis by Hibiscus rosa sinensis extract and the role of its chemical constituent, gentisic acid, in the inhibition of tumour promotion response and oxidative stress in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Carcinogens; Croton Oil; Dose-Response Relationship, Drug; Female; Gentisates; Glutathione; Hibiscus; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Mice; Ornithine Decarboxylase; Oxidative Stress; Phytotherapy; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Crosstalk between PARP-1 and NF-kappaB modulates the promotion of skin neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Binding Sites; Carcinogens; Cell Division; Disease Progression; Enzyme Activation; Epidermis; Epithelium; Inflammation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Fluorescence; Mitosis; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Novel p21-activated kinase-dependent protrusions characteristically formed at the edge of transformed cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Actins; Animals; Calcium-Binding Proteins; Carcinogens; cdc42 GTP-Binding Protein; Cell Cycle Proteins; Cell Line, Transformed; Cell Line, Tumor; Cell Size; Cell Surface Extensions; Cell Transformation, Neoplastic; Enzyme Activation; Epithelial Cells; Guanine Nucleotide Exchange Factors; Lysophospholipids; Microscopy, Electron, Scanning; Models, Biological; p21-Activated Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Inbred F344; Rho Guanine Nucleotide Exchange Factors; Tetradecanoylphorbol Acetate; Time Factors; Trachea | 2004 |
Effects of the Geiji-Bokryung-Hwan on carrageenan-induced inflammation in mice and cyclooxygenase-2 in hepatoma cells of HepG2 and Hep3B.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Hepatocellular; Carrageenan; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Edema; Female; Hindlimb; Humans; Hydroquinones; Indomethacin; Inflammation; Isoenzymes; Liver Neoplasms; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Phenylbutazone; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tyrphostins | 2004 |
In situ reduction of oxidative damage, increased cell turnover, and delay of mitochondrial injury by overexpression of manganese superoxide dismutase in a multistage skin carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Cytoplasm; DNA, Complementary; Female; Humans; Immunohistochemistry; Keratinocytes; Kinetics; Mice; Mice, Transgenic; Microscopy, Electron; Mitochondria; Oxygen; Signal Transduction; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Increased skin carcinogenesis in a keratinocyte directed thioredoxin-1 transgenic mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Female; Humans; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thioredoxins; Ultraviolet Rays | 2004 |
Modulation of patched-associated susceptibility to radiation induced tumorigenesis by genetic background.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allelic Imbalance; Animals; Carcinogens; Carcinoma, Basal Cell; Female; Genetic Predisposition to Disease; Inbreeding; Intracellular Signaling Peptides and Proteins; Loss of Heterozygosity; Male; Membrane Proteins; Mice; Neoplasms, Radiation-Induced; Patched Receptors; Patched-1 Receptor; Proteins; Receptors, Cell Surface; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Experimental study to test the potential tumor promotion effect of a tooth bleaching agent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carbamide Peroxide; Carcinogens; Cricetinae; Disease Models, Animal; Drug Combinations; Female; Hyperplasia; Male; Mesocricetus; Mice; Mice, Inbred SENCAR; Mouth Mucosa; Mouth Neoplasms; Oxidants; Peroxides; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tooth Bleaching; Urea | 2001 |
Early detection of alterations associated to oral cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Analysis of Variance; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cheek; Cricetinae; Hyperplasia; Mesocricetus; Mouth Neoplasms; Neoplasms, Radiation-Induced; Nucleolus Organizer Region; Silver Staining; Statistics, Nonparametric; Tetradecanoylphorbol Acetate | 2000 |
Alpha 2-HS glycoprotein (fetuin-A) modulates murine skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; alpha-2-HS-Glycoprotein; Animals; Apoptosis; Blood Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mutation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Mutually exclusive mutations of the Pten and ras pathways in skin tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Genes, ras; Heterozygote; Homozygote; Loss of Heterozygosity; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Mutation; Papilloma; Protein Tyrosine Phosphatases; PTEN Phosphohydrolase; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Proteins | 2004 |
Effect of Onosma echioides on DMBA/croton oil mediated carcinogenic response, hyperproliferation and oxidative damage in murine skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoyl Peroxide; Boraginaceae; Carcinogens; Catalase; Cell Division; Croton Oil; DNA; Female; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hydrogen Peroxide; Malondialdehyde; Mice; Ornithine Decarboxylase; Oxidative Stress; Phytotherapy; Plant Extracts; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2004 |
Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in CD-1 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anthocyanins; Carcinogens; Cyclooxygenase 2; Edema; Epidermis; Female; Fruit; Hydrolyzable Tannins; Hyperplasia; I-kappa B Kinase; Isoenzymes; Lythraceae; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Ornithine Decarboxylase; Phosphorylation; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Signal Transduction; Skin Neoplasms; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetradecanoylphorbol Acetate | 2005 |
Modulatory effect of Morus indica against two-stage skin carcinogenesis in Swiss albino mice: possible mechanism by inhibiting aryl hydrocarbon hydroxylase.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Antioxidants; Aryl Hydrocarbon Hydroxylases; Carcinogens; Croton Oil; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA Damage; Enzyme Inhibitors; Female; Lipid Peroxidation; Male; Mice; Morus; Ornithine Decarboxylase Inhibitors; Oxidative Stress; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2004 |
Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mutation; Phosphoinositide Phospholipase C; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2004 |
Potential anti-tumor promoting activity of lupane-type triterpenoids from the stem bark of Glochidion zeylanicum and Phyllanthus flexuosus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Female; Herpesvirus 4, Human; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Papilloma; Phyllanthus; Phytotherapy; Plant Bark; Plant Extracts; Skin Neoplasms; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Triterpenes | 2004 |
Haploinsufficiency for odc modifies mouse skin tumor susceptibility.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biogenic Polyamines; Carcinogens; Cocarcinogenesis; Enzyme Induction; Female; Genetic Predisposition to Disease; Haploidy; Male; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
The effect of PPARgamma ligands on UV- or chemically-induced carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Chromans; Diet; Female; Keratinocytes; Ligands; Mice; PPAR gamma; RNA, Messenger; Rosiglitazone; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thiazolidinediones; Troglitazone; Ultraviolet Rays | 2005 |
Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Growth Processes; Cell Transformation, Neoplastic; Chromosome Mapping; DNA Damage; DNA-Binding Proteins; Early Growth Response Protein 1; Female; Fibroblasts; Gene Expression Profiling; Genes, Tumor Suppressor; Immediate-Early Proteins; Male; Mice; Mice, Inbred C57BL; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Suppressor Protein p53; Up-Regulation | 2005 |
Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Carcinogens; Caspase 3; Caspases; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; DNA, Antisense; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Papilloma; Phosphoproteins; Sarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2005 |
Prostaglandin E receptor EP3 deficiency modifies tumor outcome in mouse two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cadherins; Carcinoma, Squamous Cell; Female; Incidence; Keratoacanthoma; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate; Treatment Outcome | 2005 |
Mice lacking the p53/p63 target gene Perp are resistant to papilloma development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Adhesion; Cell Differentiation; Cell Growth Processes; Female; Gene Silencing; Genes, p53; Genetic Predisposition to Disease; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Papilloma; Phosphoproteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators | 2005 |
Reduced excision repair cross-complementing 1 expression associates with enhanced papilloma formation and fibroblast transformation after genetic disruption of secreted protein acidic and rich in cysteine.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; DNA Adducts; DNA-Binding Proteins; Embryo, Mammalian; Endonucleases; Female; Fibroblasts; Gene Expression; Genotype; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Osteonectin; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Methylation of the O6-methylguanine-DNA methyltransferase promoter suppresses expression in mouse skin tumors and varies with the tumor induction protocol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Diterpenes; DNA Methylation; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Methylnitronitrosoguanidine; Mice; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Papilloma; Promoter Regions, Genetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Deficiency of protein kinase Calpha in mice results in impairment of epidermal hyperplasia and enhancement of tumor formation in two-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Cytokines; DNA; Female; Hyperplasia; Keratinocytes; Mice; Protein Kinase C; Protein Kinase C-alpha; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cell Line, Tumor; Disease Susceptibility; Down-Regulation; Female; Immunologic Surveillance; Killer Cells, Natural; Ligands; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; NK Cell Lectin-Like Receptor Subfamily K; Papilloma; Receptors, Immunologic; Receptors, Natural Killer Cell; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Burden | 2005 |
Two distinct activities contribute to human papillomavirus 16 E6's oncogenic potential.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Viral; DNA; Human papillomavirus 16; Humans; Membrane Proteins; Mice; Mice, Transgenic; Oncogene Proteins, Viral; Protein Structure, Tertiary; Repressor Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; CCAAT-Enhancer-Binding Protein-beta; Female; Integrases; Keratin-15; Keratin-5; Keratinocytes; Keratins; Mice; Mice, Inbred C57BL; Mice, Knockout; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Lack of expression of the EP2 but not EP3 receptor for prostaglandin E2 results in suppression of skin tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Cyclic AMP; Dinoprostone; Drug Eruptions; Female; Hyperplasia; Keratinocytes; Mice; Mice, Knockout; Neovascularization, Pathologic; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Receptors, Prostaglandin E, EP3 Subtype; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Early epidermal destruction with subsequent epidermal hyperplasia is a unique feature of the papilloma-independent squamous cell carcinoma phenotype in PKCepsilon overexpressing transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Death; Cell Differentiation; Cell Proliferation; Chemotaxis, Leukocyte; Cocarcinogenesis; Disease Models, Animal; Epidermis; Female; Hair Follicle; Hyperplasia; Keratin-10; Keratinocytes; Keratins; Mice; Mice, Transgenic; Neutrophils; Phenotype; Precancerous Conditions; Protein Kinase C-epsilon; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2005 |
Overexpression of extracellular superoxide dismutase (EC-SOD) in mouse skin plays a protective role in DMBA/TPA-induced tumor formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Proliferation; DNA Damage; Mice; Mice, Inbred C57BL; Mice, Transgenic; Reactive Oxygen Species; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2005 |
p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Growth Processes; Cocarcinogenesis; Keratinocytes; Male; MAP Kinase Signaling System; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Cell Proliferation; Cell Transformation, Neoplastic; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Minichromosome Maintenance Complex Component 7; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Nuclear Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Effect of radiofrequency radiation exposure on mouse skin tumorigenesis initiated by 7,12-dimethybenz[alpha]anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Phone; Dose-Response Relationship, Radiation; Electromagnetic Fields; Male; Mice; Mice, Inbred ICR; Neoplasms, Radiation-Induced; Random Allocation; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2005 |
Association of gene expression with sequential proliferation, differentiation and tumor formation in murine skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Female; Filaggrin Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Ras mutation promotes p53 activation and apoptosis of skin keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Enzyme Inhibitors; Genes, ras; Keratinocytes; Mice; Mice, Inbred C57BL; Mitochondria; Mutation; NADPH Oxidases; Onium Compounds; Protein Transport; rac1 GTP-Binding Protein; Reactive Oxygen Species; RNA, Small Interfering; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2006 |
Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaline Phosphatase; Animals; Blotting, Western; Carcinogenicity Tests; Carcinogens; Cell Culture Techniques; Cells, Cultured; Chlorocebus aethiops; COS Cells; Eosine Yellowish-(YS); Female; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Hematoxylin; Histocytochemistry; Hydroquinones; Keratinocytes; Mice; Mice, Transgenic; Microscopy, Fluorescence; Models, Biological; NF-E2-Related Factor 2; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wound Healing | 2006 |
Electrochemical behavior and determination of tumor inhibiting or promoting activities of flavonoids.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anticarcinogenic Agents; Carcinogenicity Tests; Carcinogens; Cocarcinogenesis; Flavonoids; Polarography; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2006 |
Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Growth Processes; Cell Transformation, Neoplastic; Enzyme Activation; Ephrin-A1; Female; Genetic Predisposition to Disease; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptor, EphA2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Papilloma development is delayed in osteopontin-null mice: implicating an antiapoptosis role for osteopontin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Growth Processes; Epidermis; Female; Male; Mice; Osteopontin; Papilloma; Sialoglycoproteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2006 |
Skin epidermis lacking the c-Myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21Cip1 gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Proto-Oncogene Proteins c-myc; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Cell Line; Cocarcinogenesis; Cyclooxygenase 2; Female; Flavones; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2006 |
Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Antigens, Viral; Antineoplastic Agents; Basidiomycota; Cell Line, Tumor; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Female; Lanosterol; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred ICR; Models, Molecular; Molecular Conformation; Plant Extracts; Reference Standards; Stereoisomerism; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Triterpenes; Xenograft Model Antitumor Assays | 2007 |
Cancer chemopreventive activity of lupane- and oleanane-type triterpenoids from the cones of Liquidamber styraciflua.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Chromatography, Gel; Humans; Liquidambar; Mice; Neoplasms, Experimental; Oleanolic Acid; Tetradecanoylphorbol Acetate; Triterpenes | 2005 |
Inhibitory effects of asiatic acid on 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Induction; Female; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type II; Papilloma; Pentacyclic Triterpenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes | 2007 |
Pro/antioxidant status and AP-1 transcription factor in murine skin following topical exposure to cumene hydroperoxide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzene Derivatives; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Female; Gene Expression Regulation, Neoplastic; Glutathione; Mice; Mice, Transgenic; Oxidation-Reduction; Oxidative Stress; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2007 |
Malignant transformation of DMBA/TPA-induced papillomas and nevi in the skin of mice selectively lacking retinoid-X-receptor alpha in epidermal keratinocytes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Epidermis; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Transgenic; Nevus, Pigmented; Papilloma; PPAR gamma; Retinoid X Receptor alpha; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Chemopreventive effects of sarcophine-diol on skin tumor development in CD-1 mice.
Topics: 4-Butyrolactone; 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Caspase 3; Caspase 8; Caspase 9; Cell Proliferation; Cyclooxygenase 2; Female; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; CCAAT-Enhancer-Binding Proteins; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Transgenic; NF-kappa B; Oncogene Proteins, Viral; Osteopontin; Papillomavirus E7 Proteins; Peptide Fragments; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Transfection | 2007 |
The ends of a conundrum?
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Binding Sites; Carcinogens; Cell Proliferation; Cells, Cultured; Disease Susceptibility; Epidermal Cells; Intermediate Filaments; Keratin-10; Keratin-14; Keratin-5; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mice, Transgenic; Protein Binding; Protein Structure, Tertiary; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Haploinsufficiency of the cdc2l gene contributes to skin cancer development in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Codon; Crosses, Genetic; DNA Helicases; Female; Genes, ras; Male; Mice; Mice, Inbred C57BL; Minichromosome Maintenance Complex Component 4; Papilloma; Polymorphism, Restriction Fragment Length; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Dual role of inactivating Lef1 mutations in epidermis: tumor promotion and specification of tumor type.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma, Sebaceous; Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Female; Genes, ras; Lymphoid Enhancer-Binding Factor 1; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Mutation; Sebaceous Gland Neoplasms; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2007 |
CD34 expression by hair follicle stem cells is required for skin tumor development in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD34; Cell Cycle; Cell Movement; Female; Hair Follicle; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate | 2007 |
Triterpene acids from Poria cocos and their anti-tumor-promoting effects.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anticarcinogenic Agents; Antigens, Viral; Humans; Molecular Structure; Plants, Medicinal; Polyporaceae; Tetradecanoylphorbol Acetate; Triterpenes | 2007 |
DMBA/TPA-induced tumor formation is aggravated in human papillomavirus type 16 E6/E7 transgenic mouse skin.
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Deoxyguanosine; Dermis; DNA Damage; Epidermis; Gene Expression; Humans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Repressor Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Expression profile of skin papillomas with high cancer risk displays a unique genetic signature that clusters with squamous cell carcinomas and predicts risk for malignant conversion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers, Tumor; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Gene Expression Profiling; Immunity, Cellular; Immunophenotyping; Mice; Mice, Inbred SENCAR; Oligonucleotide Array Sequence Analysis; Papilloma; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Melanocyte expression of survivin promotes development and metastasis of UV-induced melanoma in HGF-transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Growth Processes; Female; Hepatocyte Growth Factor; Inhibitor of Apoptosis Proteins; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Microtubule-Associated Proteins; Nevus, Pigmented; Repressor Proteins; Skin Pigmentation; Survivin; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2007 |
The effect of cyclooxygenase-2 overexpression on skin carcinogenesis is context dependent.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anthralin; Blotting, Northern; Blotting, Western; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Dermatologic Agents; Drug Resistance, Neoplasm; Female; Humans; Interleukin-1alpha; Mice; Mice, Transgenic; Ornithine Decarboxylase; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chromosome Mapping; Crosses, Genetic; Drug Resistance; Female; Genes, Dominant; Genetic Linkage; Genetic Predisposition to Disease; Genotype; Male; Mice; Mice, Inbred Strains; Neoplasms, Second Primary; Papilloma; Quantitative Trait Loci; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Design, semisynthesis, and evaluation of O-acyl derivatives of (-)-epigallocatechin-3-gallate as antitumor agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acylation; Animals; Antineoplastic Agents, Phytogenic; Catechin; Mice; Neoplasms, Experimental; Tea; Tetradecanoylphorbol Acetate | 2007 |
Protective effect of Ocimum sanctum on 3-methylcholanthrene, 7,12-dimethylbenz(a)anthracene and aflatoxin B1 induced skin tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Cocarcinogenesis; Female; gamma-Glutamyltransferase; Glutathione; Glutathione S-Transferase pi; HSP70 Heat-Shock Proteins; Interleukin-1beta; Lipid Peroxidation; Methylcholanthrene; Mice; Ocimum; Ornithine Decarboxylase; Plant Extracts; Plant Leaves; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2007 |
Decreased c-kit function inhibits enhanced skin carcinogenesis in c-Ha-ras protooncogene transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Humans; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Papilloma; Polymerase Chain Reaction; Promoter Regions, Genetic; Proto-Oncogene Proteins c-kit; Proto-Oncogene Proteins p21(ras); Skin Neoplasms; Tetradecanoylphorbol Acetate; Transgenes | 2007 |
Cucurbitane-type triterpenoids from the fruits of Momordica charantia and their cancer chemopreventive effects.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Fruit; Glycosides; Humans; Inhibitory Concentration 50; Mice; Molecular Structure; Momordica charantia; Nitric Oxide Donors; Peroxynitrous Acid; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2007 |
Expression of the human Cathepsin L inhibitor hurpin in mice: skin alterations and increased carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cathepsin L; Cathepsins; Cell Transformation, Neoplastic; Cysteine Endopeptidases; Humans; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Serpins; Skin; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2007 |
Forced expression of a constitutively active form of Stat3 in mouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Epidermis; Keratinocytes; Mice; Mice, Transgenic; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate | 2008 |
In vivo long-term effects of retinoic acid exposure in utero on induced hyperplastic epidermal foci in murine skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Cell Differentiation; Disease Models, Animal; Female; Keratolytic Agents; Mice; Papilloma; Pregnancy; Prenatal Exposure Delayed Effects; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 2007 |
Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; DNA-Binding Proteins; Fibroblasts; Gene Expression Regulation, Neoplastic; Genotype; Glucose; Heat Shock Transcription Factors; Humans; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Mice, Knockout; Mutation; Phenotype; Protein Biosynthesis; Proto-Oncogene Proteins c-sis; ras Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transduction, Genetic; Tumor Suppressor Protein p53 | 2007 |
Regulation of p53, nuclear factor kappaB and cyclooxygenase-2 expression by bromelain through targeting mitogen-activated protein kinase pathway in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Bromelains; Cyclooxygenase 2; Female; MAP Kinase Signaling System; Mice; NF-kappa B; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2008 |
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Amino Acid Sequence; Animals; Base Sequence; Carcinogens; Carcinoma; Cocarcinogenesis; Female; Genes, ras; Genetic Predisposition to Disease; I-kappa B Kinase; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Neovascularization, Pathologic; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2007 |
Changes in the distribution pattern of Claudin tight junction proteins during the progression of mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Claudin-1; Disease Progression; Epidermis; Gene Expression; Membrane Proteins; Mice; Models, Animal; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tight Junctions; Time Factors | 2007 |
RasGRP1 overexpression in the epidermis of transgenic mice contributes to tumor progression during multistage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Progression; Epidermis; Female; Guanine Nucleotide Exchange Factors; Keratinocytes; Male; Mice; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Chemotherapeutic/chemopreventive role of retinoids in chemically induced skin carcinogenesis in albino mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Diterpenes; Isotretinoin; Mice; Precancerous Conditions; Retinyl Esters; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin A | 2007 |
p19/Arf and p53 suppress sentinel lymph node lymphangiogenesis and carcinoma metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; B-Lymphocytes; Carcinoma, Squamous Cell; Cell Proliferation; Chemotaxis, Leukocyte; Cyclin-Dependent Kinase Inhibitor p16; Lymph Nodes; Lymphangiogenesis; Lymphatic Metastasis; Macrophages; Mice; Mice, Transgenic; Neovascularization, Pathologic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2008 |
Imiquimod treatment of papilloma virus and DMBA /TPA-induced cutaneous skin cancer in Mastomys coucha: an unique animal model system useful for preclinical studies.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoquinolines; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Evaluation, Preclinical; Imiquimod; Murinae; Papilloma; Papillomavirus Infections; Skin Neoplasms; Tetradecanoylphorbol Acetate; Treatment Outcome | 2007 |
Differential tumor biology effects of double-initiation in a mouse skin chemical carcinogenesis model comparing wild type versus protein kinase Cepsilon overexpression mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinoma, Squamous Cell; Female; Genes, ras; Mice; Mice, Transgenic; Mutation; Papilloma; Protein Kinase C-epsilon; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2007 |
Hmga1 null mice are less susceptible to chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Genetic Predisposition to Disease; HMGA Proteins; Keratinocytes; Mice; Mice, Knockout; Papilloma; Proto-Oncogene Proteins c-fos; rab GTP-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
RETRACTED: Resveratrol induces apoptosis involving mitochondrial pathways in mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antioxidants; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Carcinogens; Chemoprevention; Cytochromes c; Disease Models, Animal; In Situ Nick-End Labeling; Male; Mice; Mitochondria; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Resveratrol; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate | 2008 |
RAGE signaling sustains inflammation and promotes tumor development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Gene Expression Regulation, Neoplastic; Inflammation; Macrophage Inflammatory Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor for Advanced Glycation End Products; Receptors, Immunologic; S100 Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Suppressor role of activating transcription factor 2 (ATF2) in skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Activating Transcription Factor 2; Animals; Apoptosis; beta Catenin; Carcinogens; Cell Proliferation; Cyclin D1; DNA; Epidermis; Keratinocytes; Mice; Mice, Knockout; Papilloma; Presenilin-1; Proto-Oncogene Proteins c-myb; Receptor, Notch1; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tissue Array Analysis; Tumor Suppressor Proteins | 2008 |
Cancer chemoprotective effects of Curcuma xanthorrhiza.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Curcuma; Dose-Response Relationship, Drug; Ear; Edema; Female; Humans; Methanol; Mice; Mice, Inbred ICR; Mutagenesis; Phytotherapy; Plant Extracts; Salmonella typhimurium; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Polymeric black tea polyphenols inhibit mouse skin chemical carcinogenesis by decreasing cell proliferation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Nucleus; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Epidermis; Female; Flavonoids; Inflammation Mediators; MAP Kinase Signaling System; Mice; Ornithine Decarboxylase; Phenols; Polymers; Polyphenols; Precancerous Conditions; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Tea; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Suppressor Protein p53 | 2008 |
Inhibitory effect of the rhizomes of Alpinia officinarum on TPA-induced inflammation and tumor promotion in two-stage carcinogenesis in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alpinia; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Carcinogens; Diarylheptanoids; Female; Inflammation; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Plant Extracts; Rhizome; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Cancer chemopreventive activity of "rosin" constituents of Pinus spez. and their derivatives in two-stage mouse skin carcinogenesis test.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carboxylic Acids; Carcinogenicity Tests; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred ICR; Papilloma; Phenanthrenes; Pinus; Resins, Plant; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Immunohistochemistry; Mice; Mice, Transgenic; Polymerase Chain Reaction; Signal Transduction; Skin Neoplasms; STAT3 Transcription Factor; Tamoxifen; Tetradecanoylphorbol Acetate | 2008 |
Effects of oral administration of ciclosporin A on skin carcinogenesis: a study using the two-stage carcinogenesis protocol in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinogens; Cyclosporine; Dose-Response Relationship, Drug; Female; Immunosuppressive Agents; Mice; Mice, Hairless; Neoplasm Staging; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Lantadenes and their esters as potential antitumor agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Female; HeLa Cells; HL-60 Cells; Humans; India; Lantana; Mice; Mice, Inbred Strains; Oleanolic Acid; Plant Leaves; Plants, Medicinal; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2008 |
Guggulsterone modulates MAPK and NF-kappaB pathways and inhibits skin tumorigenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cyclooxygenase 2 Inhibitors; Edema; Female; Hyperplasia; I-kappa B Kinase; I-kappa B Proteins; MAP Kinase Signaling System; Mice; Mice, Inbred SENCAR; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase Type II; Ornithine Decarboxylase Inhibitors; Phosphorylation; Pregnenediones; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2008 |
Promotion of mouse two-stage skin carcinogenesis by diacylglycerol-rich edible oil.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Diglycerides; Fatty Acids; Female; Fluocinolone Acetonide; Linoleic Acid; Mice; Oils; Oleic Acid; Protein Kinase C; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
The human promyelocytic leukemia protein is a tumor suppressor for murine skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; DNA Primers; Genes, Tumor Suppressor; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nuclear Proteins; Polymerase Chain Reaction; Promyelocytic Leukemia Protein; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Suppressor Proteins | 2009 |
Antitumor-promoting effects of polyphenolic extracts from seedless and seeded Indian grapes.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogenicity Tests; Esophageal Neoplasms; Female; Flavonoids; India; Male; Mice; Mice, Inbred Strains; Phenols; Plant Extracts; Polyphenols; Seeds; Skin Neoplasms; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Vitis | 2008 |
Inducible cutaneous inflammation reveals a protumorigenic role for keratinocyte CXCR2 in skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Drug Eruptions; Enzyme Activation; Female; Hair Follicle; HeLa Cells; Humans; Keratinocytes; Ligands; Male; Mice; Neutrophils; Protein Kinase C-alpha; Receptors, Interleukin-8B; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Dietary grape seed proanthocyanidins inhibit 12-O-tetradecanoyl phorbol-13-acetate-caused skin tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated mouse skin, which is associated with the inhibition of inflammatory responses.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cyclin D1; Cyclooxygenase 2; Dinoprostone; Female; Grape Seed Extract; Inflammation; Mice; Papilloma; Plant Extracts; Proanthocyanidins; Proliferating Cell Nuclear Antigen; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Disease Models, Animal; Drug Screening Assays, Antitumor; Edema; Extracellular Signal-Regulated MAP Kinases; Female; Hyperplasia; Inflammation; Mice; Monoterpenes; Oxidative Stress; ras Proteins; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
IFNgamma promotes papilloma development by up-regulating Th17-associated inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Inflammation; Interferon gamma Receptor; Interferon-gamma; Interleukin-17; Mice; Papilloma; Phosphorylation; Receptors, Interferon; Skin Neoplasms; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate | 2009 |
Hypoxia-inducible factor-1alpha suppresses squamous carcinogenic progression and epithelial-mesenchymal transition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle Proteins; Disease Progression; Epithelial Cells; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Selenium-Binding Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Bromelain inhibits COX-2 expression by blocking the activation of MAPK regulated NF-kappa B against skin tumor-initiation triggering mitochondrial death pathway.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Bromelains; Cyclooxygenase 2 Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Mice; Mitochondria; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2009 |
Activation of P2X(7)-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenosine Triphosphate; Animals; Apoptosis; Blotting, Western; Calcium; Caspase 3; Caspase 9; Caspase Inhibitors; Cells, Cultured; Dose-Response Relationship, Drug; Female; Immunohistochemistry; In Situ Nick-End Labeling; Keratinocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Papilloma; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Survival Analysis; Tetradecanoylphorbol Acetate | 2009 |
Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Genotype; Hyperplasia; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Knockout; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oncogene Protein v-akt; Papilloma; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Photodynamic therapy using a novel photosensitizer, EC036, is more effective compared with ATX-S10(Na) photodynamic therapy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Female; Lasers, Semiconductor; Mice; Mice, Hairless; Ointments; Papilloma; Photochemotherapy; Photosensitizing Agents; Porphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2009 |
Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Blotting, Western; Carcinogens; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression; Immunohistochemistry; MAP Kinase Kinase Kinases; Mice; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins B-raf; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 2009 |
Inhibition of CREB function in mouse epidermis reduces papilloma formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Carcinogens; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Epidermis; Female; Genes, ras; In Situ Nick-End Labeling; Keratinocytes; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Mutation; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: involvement of inflammation, Ras-ERK pathway and apoptosis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Chemoprevention; Cyclooxygenase 2; Disease Models, Animal; Drug Screening Assays, Antitumor; Extracellular Signal-Regulated MAP Kinases; Farnesol; Inflammation; Mice; Ornithine Decarboxylase; Oxidative Stress; ras Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angiogenesis Inhibitors; Animals; Blood Vessels; Carcinogens; Cell Transformation, Neoplastic; Female; Genotype; Immunohistochemistry; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Neoplasms, Experimental; NIH 3T3 Cells; Resveratrol; Sirtuin 1; Sirtuins; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Transfection | 2009 |
Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Kaplan-Meier Estimate; Mice; Mice, Inbred Strains; Papilloma; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Anti-tumor promoters phenolics and triterpenoid from Hippophae rhamnoides.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Catechin; Female; Hippophae; Inflammation; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Plant Stems; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2009 |
Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Epidermis; Gene Deletion; Genes, Tumor Suppressor; Homeodomain Proteins; Mice; Mice, Knockout; Receptor, Notch1; Skin Neoplasms; Stromal Cells; Tetradecanoylphorbol Acetate | 2009 |
Cancer chemopreventive activity of diversin from Ferula diversivittata in vitro and in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Carcinogens; Coumarins; Female; Ferula; Lactones; Mice; Mice, Inbred ICR; Monoterpenes; Papilloma; Phytotherapy; Plant Extracts; Plant Roots; Sesquiterpenes; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
RIP4 regulates epidermal differentiation and cutaneous inflammation.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Differentiation; Dermatitis, Contact; Epidermis; Female; Humans; I-kappa B Kinase; Keratin-14; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pregnancy; Promoter Regions, Genetic; Protein Kinase C; Protein Kinases; Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor, Type I; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
Relative inhibitory activity of bile acids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation, and chenodeoxycholic acid inhibition of tumour promotion in mouse skin two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Bile Acids and Salts; Carcinogens; Chenodeoxycholic Acid; Disease Models, Animal; Edema; Female; Indomethacin; Inflammation; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2009 |
IL-12 deficiency suppresses 12-O-tetradecanoylphorbol-13-acetate-induced skin tumor development in 7,12-dimethylbenz(a)anthracene-initiated mouse skin through inhibition of inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cyclin D1; Cyclooxygenase 2; Cytokines; Female; Inflammation; Interleukin-12 Subunit p40; Interleukin-6; Mice; Mice, Knockout; Proliferating Cell Nuclear Antigen; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Studies on glyphosate-induced carcinogenicity in mouse skin: a proteomic approach.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Glycine; Glyphosate; Herbicides; Mice; Proteomics; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2010 |
The effect of c-myc on stem cell fate influences skin tumor phenotype.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma, Sebaceous; Animals; Carcinogens; Cell Differentiation; Cell Lineage; Crosses, Genetic; Female; Heterozygote; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Mice, Transgenic; Multipotent Stem Cells; Papilloma; Phenotype; Proto-Oncogene Proteins c-myc; Sebaceous Gland Neoplasms; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Transgenes | 2010 |
Positron emission tomography imaging of DMBA/TPA mouse skin multi-step tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Progression; Female; Fluorodeoxyglucose F18; Glucose; Mice; Papilloma; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tomography, X-Ray Computed | 2010 |
Diallyl trisulfide inhibits phorbol ester-induced tumor promotion, activation of AP-1, and expression of COX-2 in mouse skin by blocking JNK and Akt signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Allyl Compounds; Animals; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Down-Regulation; Drug Interactions; Enzyme Activation; Enzyme Induction; Female; Humans; MAP Kinase Kinase 4; Mice; Mice, Inbred ICR; Proto-Oncogene Proteins c-akt; Signal Transduction; Skin; Skin Neoplasms; Sulfides; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2010 |
Genetic heterogeneity of inflammatory response and skin tumorigenesis in phenotypically selected mouse lines.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Genetic Drift; Genetic Heterogeneity; Genetic Predisposition to Disease; Genome-Wide Association Study; Inflammation; Mice; Neutrophil Infiltration; Papilloma; Phenotype; Polymorphism, Single Nucleotide; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
The immunosuppressive surface ligand CD200 augments the metastatic capacity of squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Antigens, Surface; Carcinoma, Squamous Cell; Cell Growth Processes; Female; Gene Knockdown Techniques; Humans; Keratinocytes; Membrane Glycoproteins; Mice; Orexin Receptors; Receptors, Cell Surface; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Proliferation; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Genes, ras; Keratinocytes; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Neuropeptides; p21-Activated Kinases; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
Anti-inflammatory and chemopreventive effects of triterpene cinnamates and acetates from shea fat.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Animals; Anti-Inflammatory Agents; Antigens, Viral; Antineoplastic Agents, Phytogenic; Carrageenan; Cell Line, Tumor; Cinnamates; Dose-Response Relationship, Drug; Edema; Female; Hindlimb; Mice; Mice, Inbred ICR; Sapotaceae; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Triterpenes | 2010 |
Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Bone Marrow; Bone Marrow Transplantation; Carcinogens; Drug Synergism; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interferon-gamma; Interleukin-1beta; Keratinocytes; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Escape; Tumor Suppressor Proteins; U937 Cells; Whole-Body Irradiation | 2010 |
Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capsaicin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cocarcinogenesis; Cyclooxygenase 2; Drug Synergism; Enzyme Activation; ErbB Receptors; Female; Humans; Male; Mice; Mice, Knockout; Signal Transduction; Skin Neoplasms; src-Family Kinases; Tetradecanoylphorbol Acetate; TRPV Cation Channels | 2010 |
Chemopreventive activity of Azadirachta indica on two-stage skin carcinogenesis in murine model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Azadirachta; Carcinoma; Disease Models, Animal; Male; Mice; Plant Extracts; Plant Leaves; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
AP1 factor inactivation in the suprabasal epidermis causes increased epidermal hyperproliferation and hyperkeratosis but reduced carcinogen-dependent tumor formation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Carcinogens; Cell Proliferation; DNA Primers; Epidermis; Mice; Mice, Transgenic; Neoplasms, Experimental; Polymerase Chain Reaction; Skin Diseases; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2010 |
Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Cell Transformation, Neoplastic; Extracellular Signal-Regulated MAP Kinases; Humans; Inflammation; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Phosphorylation; ras Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 2010 |
Intrinsic cooperation between p16INK4a and p21Waf1/Cip1 in the onset of cellular senescence and tumor suppression in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Embryo, Mammalian; Fibroblasts; Histones; Mice; Mice, Inbred C57BL; Mice, Knockout; Octamer Transcription Factor-3; ras Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2010 |
Lack of skin carcinogenicity of topically applied titanium dioxide nanoparticles in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Body Weight; Carcinogenicity Tests; Metal Nanoparticles; Mice; Mice, Inbred ICR; Skin Neoplasms; Survival Rate; Tetradecanoylphorbol Acetate; Titanium | 2011 |
Carcinogen-induced squamous papillomas and oncogenic progression in the absence of the SSeCKS/AKAP12 metastasis suppressor correlate with FAK upregulation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; A Kinase Anchor Proteins; Animals; Cell Cycle Proteins; Disease Progression; Focal Adhesion Kinase 1; Gene Expression Regulation, Neoplastic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2011 |
Glutathione-conjugate transport by RLIP76 is required for clathrin-dependent endocytosis and chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Carcinogens; Clathrin; Drug Resistance, Neoplasm; Endocytosis; Female; Glutathione; GTPase-Activating Proteins; Humans; Male; Mice; Mice, Knockout; Protein Kinase C-alpha; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Tumor Suppressor Protein p53 | 2011 |
FSP1+ fibroblasts promote skin carcinogenesis by maintaining MCP-1-mediated macrophage infiltration and chronic inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Chemokine CCL2; Chronic Disease; Fibroblasts; Humans; Inflammation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Upregulation of the EP1 receptor for prostaglandin E2 promotes skin tumor progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Blotting, Western; Carcinogens; Cell Proliferation; Cyclooxygenase 2; Dinoprostone; Disease Progression; Epidermis; Female; Humans; Mice; Mice, Hairless; Mice, Transgenic; Receptors, Prostaglandin E, EP1 Subtype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays; Up-Regulation | 2011 |
Decreased incidence of papillomas in mice with impaired EGFR function during multi-stage skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Proliferation; ErbB Receptors; Ki-67 Antigen; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 2011 |
Effect of suppressive oligodeoxynucleotides on the development of inflammation-induced papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Chemokine CCL2; Chemokine CXCL2; Cyclooxygenase 2; Female; Inflammation; Mice; Oligodeoxyribonucleotides; Ornithine Decarboxylase; Papilloma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Re-assessing K15 as an epidermal stem cell marker.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biomarkers; Cell Differentiation; Embryo, Mammalian; Embryonic Development; Epidermis; Gene Expression Regulation, Neoplastic; Homeostasis; Keratin-15; Mice; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Time Factors | 2011 |
The arcuate nucleus and neuropeptide Y contribute to the antitumorigenic effect of calorie restriction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Appetite; Arcuate Nucleus of Hypothalamus; Caloric Restriction; Female; Hunger; Male; Mice; Mice, Knockout; Neoplasms, Experimental; Neurons; Neuropeptide Y; Papilloma; RNA, Messenger; Skin Neoplasms; Sodium Glutamate; Tetradecanoylphorbol Acetate | 2011 |
CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cysteine Endopeptidases; Deubiquitinating Enzyme CYLD; Disease Progression; Epidermal Cells; Epidermis; Humans; Hyperplasia; Immunoblotting; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases; Lymphatic Metastasis; Mice; Mice, Transgenic; Mutation; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitination | 2011 |
Potential O-acyl-substituted (-)-Epicatechin gallate prodrugs as inhibitors of DMBA/TPA-induced squamous cell carcinoma of skin in Swiss albino mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Catechin; Female; Humans; Hydrolysis; Mice; Prodrugs; Skin; Skin Neoplasms; Solubility; Tea; Tetradecanoylphorbol Acetate | 2011 |
Azadirachta indica exerts chemopreventive action against murine skin cancer: studies on histopathological, ultrastructural changes and modulation of NF-kappaB, AP-1, and STAT1.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Azadirachta; Male; Mice; NF-kappa B; Plant Extracts; RNA, Messenger; Skin Neoplasms; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate; Transcription Factor AP-1 | 2011 |
Conjugates of 3α-methoxyserrat-14-en-21β-ol (PJ-1) and 3β-methoxyserrat-14-en-21β-ol (PJ-2) as cancer chemopreventive agents.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Carcinogenicity Tests; Cell Transformation, Neoplastic; Epstein-Barr Virus Infections; Flavanones; Genistein; Herpesvirus 4, Human; Hesperidin; Isoflavones; Mice; Oleanolic Acid; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2011 |
Loss of the miR-21 allele elevates the expression of its target genes and reduces tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Epidermal Cells; Epidermis; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Mice; Mice, Knockout; MicroRNAs; ras Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Asphalt fume dermal carcinogenicity potential: II. Initiation-promotion assay of Type III built-up roofing asphalt.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Air Pollutants, Occupational; Animals; Body Weight; Carcinogens; Hydrocarbons; Male; Mice; Occupational Exposure; Skin; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Rapamycin is a potent inhibitor of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Blotting, Western; Carcinogens; Humans; Hyperplasia; Mice; Neoplasm Staging; Papilloma; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2011 |
CXCR3 enhances a T-cell-dependent epidermal proliferative response and promotes skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Proliferation; Cell Transformation, Neoplastic; Epidermis; Humans; Lymphocytes, Tumor-Infiltrating; Methylcholanthrene; Mice; Mice, Mutant Strains; Receptors, CXCR3; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2011 |
Inhibitory effects of 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, β-diketone structural analogues of curcumin, on chemical-induced tumor promotion and inflammation in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Aspirin; Carcinogens; Curcumin; Dermatitis; Ear, External; Edema; Female; Ketones; Mice; Mice, Inbred Strains; Platelet Aggregation Inhibitors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
E6 and E7 from beta HPV38 cooperate with ultraviolet light in the development of actinic keratosis-like lesions and squamous cell carcinoma in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alphapapillomavirus; Animals; Carcinogens; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p21; Epidermis; Humans; Keratinocytes; Keratosis, Actinic; Mice; Mice, Transgenic; Oncogene Proteins, Viral; Papillomavirus Infections; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2011 |
Inhibitory effects of interferon-gamma plasmid DNA on DMBA-TPA induced mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Caspase 3; Cell Proliferation; Female; Genetic Therapy; Interferon-gamma; Mice; Mice, Inbred BALB C; Plasmids; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Involvement of retrotransposition of long interspersed nucleotide element-1 in skin tumorigenesis induced by 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cocarcinogenesis; Drug Synergism; Genes, ras; Green Fluorescent Proteins; Humans; Long Interspersed Nucleotide Elements; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Animal; Mutagenesis, Insertional; Neoplasm Proteins; Receptors, Aryl Hydrocarbon; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection | 2011 |
Effects of heme oxygenase-1 on induction and development of chemically induced squamous cell carcinoma in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Female; Heme Oxygenase-1; Mice; Mice, Inbred Strains; Mice, Knockout; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Resveratrol and black tea polyphenol combination synergistically suppress mouse skin tumors growth by inhibition of activated MAPKs and p53.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Phosphorylation; Polyphenols; Proliferating Cell Nuclear Antigen; Protein Stability; Remission Induction; Resveratrol; Skin Neoplasms; Stilbenes; Tea; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2011 |
14-3-3σ and p63 play opposing roles in epidermal tumorigenesis.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Blotting, Western; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Gene Silencing; Homeostasis; Keratinocytes; Mice; Mice, Mutant Strains; Phosphoproteins; Polymerase Chain Reaction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators | 2011 |
Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cell Dedifferentiation; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2011 |
Human epithelial carcinoma cytotoxicity and inhibition of DMBA/TPA induced squamous cell carcinoma in Balb/c mice by Acacia catechu heartwood.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acacia; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glutathione; Humans; Lipid Peroxidation; Liver; Mice; Mice, Inbred BALB C; Plant Preparations; Random Allocation; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2011 |
Manganese superoxide dismutase is a p53-regulated gene that switches cancers between early and advanced stages.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Disease Progression; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, Reporter; Genes, Synthetic; Humans; Mice; Mice, Transgenic; Neoplasm Proteins; Papilloma; Promoter Regions, Genetic; Recombinant Fusion Proteins; Skin Neoplasms; Sp1 Transcription Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Suppressor Protein p53 | 2011 |
Cancer preventive agents 11. Novel analogs of dimethyl dicarboxylate biphenyl as potent cancer chemopreventive agents(†).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antigens, Viral; Dioxoles; Female; Humans; Mice; Mice, Inbred ICR; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Loss of the platelet activating factor receptor in mice augments PMA-induced inflammation and cutaneous chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenosylmethionine Decarboxylase; Animals; Colon; Disease Models, Animal; Epidermis; Gene Expression Regulation, Enzymologic; Genes, APC; Intestinal Neoplasms; Mice; Mice, Transgenic; Ornithine Decarboxylase; Polyamines; Skin Neoplasms; Spermidine; Spermine; Spermine Synthase; Tetradecanoylphorbol Acetate | 2012 |
Effects of dose and duration of treatment with the tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate on mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Mice; Ornithine Decarboxylase; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1980 |
D-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Catalase; Cyclohexenes; Cyclooxygenase 2; Female; Glutathione; Inflammation; Limonene; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; raf Kinases; ras Proteins; Signal Transduction; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 2012 |
Cytotoxic activities and anti-tumor-promoting effects of microbial transformation products of prenylated chalcones from Angelica keiskei.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Angelica; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Apoptosis; Aspergillus; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Chalcones; Humans; Mice; Molecular Structure; Prenylation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2012 |
Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Glycosides; Humans; Mice; Molecular Structure; Momordica charantia; Plant Leaves; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Cells, Cultured | 2012 |
Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) and LMP2A function cooperatively to promote carcinoma development in a mouse carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Transformation, Viral; Disease Models, Animal; Disease Progression; Gene Expression; Genes, ras; Keratin-14; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mutation; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Viral Matrix Proteins | 2012 |
A keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Transformation, Neoplastic; Female; Genes, ras; Hair Follicle; Humans; Integrases; Keratin-15; Keratinocytes; Laser Capture Microdissection; Mice; Mice, Transgenic; Mutation; Papilloma; Skin; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate | 2013 |
JWA deficiency suppresses dimethylbenz[a]anthracene-phorbol ester induced skin papillomas via inactivation of MAPK pathway in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Blotting, Western; Carcinogens; Carrier Proteins; Cell Proliferation; Cells, Cultured; DNA Damage; ets-Domain Protein Elk-1; Heat-Shock Proteins; Immunohistochemistry; MAP Kinase Signaling System; Membrane Transport Proteins; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Molecular Sequence Data; Papilloma; Phosphorylation; Proliferating Cell Nuclear Antigen; Reverse Transcriptase Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Photodynamic therapy using a novel photosensitizer, TONS501, is similarly effective to ALA and EC036 photodynamic therapy on DMBA-and TPA-induced mouse skin papilloma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Aminolevulinic Acid; Animals; Disease Models, Animal; Female; Mice; Mice, Hairless; Ointments; Papilloma; Photochemotherapy; Photosensitizing Agents; Porphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Treatment Outcome | 2012 |
Deficiency of the Kruppel-like factor KLF4 correlates with increased cell proliferation and enhanced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Female; Gene Expression Regulation, Neoplastic; Humans; Keratinocytes; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Mice, Transgenic; RNA Interference; RNA, Small Interfering; Skin Neoplasms; Tamoxifen; Tetradecanoylphorbol Acetate | 2012 |
Miz1 is a critical repressor of cdkn1a during skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p21; Mice; Mice, Transgenic; Neoplasms, Experimental; Nuclear Proteins; Protein Inhibitors of Activated STAT; Protein Structure, Tertiary; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ubiquitin-Protein Ligases | 2012 |
Inotilone suppresses phorbol ester-induced inflammation and tumor promotion in mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Carcinogens; CCAAT-Enhancer-Binding Protein-beta; Cyclooxygenase 2; Dermatitis; Enzyme Activation; Female; Furans; Inflammation Mediators; Macrolides; Mice; Mice, Inbred ICR; NF-kappa B; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Tamoxifen-loaded novel liposomal formulations: evaluation of anticancer activity on DMBA-TPA induced mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Animals; Antineoplastic Agents, Hormonal; Cocarcinogenesis; Drug Compounding; Drug Delivery Systems; Female; Liposomes; Mice; Skin Neoplasms; Tamoxifen; Tetradecanoylphorbol Acetate; Treatment Outcome | 2012 |
Anti-inflammatory and anti-tumor-promoting effects of 5-deprenyllupulonol C and other compounds from Hop (Humulus lupulus L.).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antigens, Viral; Carcinogens; Edema; Female; Humulus; Magnetic Resonance Spectroscopy; Mice; Molecular Conformation; Phloroglucinol; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Effects of the tropical ginger compound,1'-acetoxychavicol acetate, against tumor promotion in K5.Stat3C transgenic mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alpinia; Animals; Benzyl Alcohols; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Fluocinolone Acetonide; Humans; Mice; Mice, Transgenic; NF-kappa B; Plant Extracts; Skin Neoplasms; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Zingiber officinale | 2012 |
Anti-tumor-promoting activities of agaro-oligosaccharides on two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Agar; Animals; Antineoplastic Agents; Carcinogens; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Edema; Humans; Intramolecular Oxidoreductases; Leukocytes, Mononuclear; Macrophages, Peritoneal; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitrites; Oligosaccharides; Prostaglandin-E Synthases; RNA, Messenger; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents, Phytogenic; Cell Proliferation; Cyclooxygenase 2; Down-Regulation; Female; Inflammation; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; Protein Kinase Inhibitors; Resveratrol; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate | 2012 |
Independent genetic control of early and late stages of chemically induced skin tumors in a cross of a Japanese wild-derived inbred mouse strain, MSM/Ms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Crosses, Genetic; Female; Genetic Linkage; Japan; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2012 |
Topical 5-fluorouracil elicits regressions of BRAF inhibitor-induced cutaneous squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Squamous Cell; Cell Line; Cell Proliferation; Fluorouracil; Humans; Imidazoles; Indoles; Melanoma; Mice; Oximes; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate; Vemurafenib | 2013 |
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Adenoma; Animals; Animals, Inbred Strains; Azoxymethane; Cell Transformation, Neoplastic; Chemokines, CXC; Colitis; Colonic Neoplasms; Dermatitis, Contact; Dextran Sulfate; Gene Expression; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Papilloma; Peroxidase; Precancerous Conditions; Receptors, Interleukin-8B; Skin Neoplasms; Statistics, Nonparametric; Tetradecanoylphorbol Acetate; Tumor Burden | 2012 |
Azadirachta indica acts as a pro-oxidant and modulates cell cycle associated proteins during DMBA/TPA induced skin carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Azadirachta; Cell Cycle; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Gene Expression; Lipid Peroxidation; Male; Mice; Plant Extracts; Proliferating Cell Nuclear Antigen; Reactive Oxygen Species; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2013 |
Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Apoptosis Regulatory Proteins; CARD Signaling Adaptor Proteins; Caspase 1; Cell Proliferation; Cell Transformation, Neoplastic; Cytokines; Cytoskeletal Proteins; Down-Regulation; Epithelium; Humans; Inflammasomes; Inflammation; Keratinocytes; Mice; Mice, Knockout; Myeloid Cells; Neoplasms, Squamous Cell; Organ Specificity; Receptors, Interleukin-1; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Microenvironment; Tumor Suppressor Protein p53 | 2012 |
The p53-p66Shc apoptotic pathway is dispensable for tumor suppression whereas the p66Shc-generated oxidative stress initiates tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Cell Transformation, Neoplastic; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidative Stress; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Ultraviolet Rays | 2013 |
Baicalein inhibits DMBA/TPA-induced skin tumorigenesis in mice by modulating proliferation, apoptosis, and inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Female; Flavanones; Hyperplasia; Inflammation; Mice; Mice, Inbred C57BL; Plant Extracts; Scutellaria baicalensis; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2013 |
Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetates; Animals; Antigens, CD34; Catechin; CCAAT-Enhancer-Binding Proteins; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitotic Index; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A | 2013 |
Anti-oxidative, anti-tumor-promoting, and anti-carcinogenic activities of adonirubin and adonixanthin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Antioxidants; Canthaxanthin; Carotenoids; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Lipid Peroxidation; Mice; Mice, Inbred ICR; Molecular Structure; Paracoccus; Singlet Oxygen; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Viral Matrix Proteins | 2013 |
Chemopreventive effects of the juice of Vitis coignetiae Pulliat on two-stage mouse skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antimutagenic Agents; Antioxidants; Carcinogens; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Edema; Fruit; Mice; Mice, Inbred SENCAR; Phenols; Phytotherapy; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitis | 2013 |
Tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in an ultra-short-term skin carcinogenesis bioassay using rasH2 mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Biological Assay; Carcinogenesis; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Transgenic; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2013 |
Effects of two disiloxanes ALIS-409 and ALIS-421 on chemoprevention in model experiments.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Viral; Breast Neoplasms; Carcinogens; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Female; Fibroblasts; Humans; Lung; Mice; Mice, Inbred ICR; Morpholines; Papilloma; Piperazines; Siloxanes; Skin Neoplasms; Stromal Cells; Tetradecanoylphorbol Acetate | 2013 |
Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Down-Regulation; Female; Genes, ras; Keratinocytes; Male; Mice; Mice, Knockout; Nuclear Proteins; Oncogene Protein p21(ras); Protein Inhibitors of Activated STAT; Proto-Oncogene Proteins c-myc; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2013 |
Modulatory effects of Azadirachta indica leaf extract on cutaneous and hepatic biochemical status during promotion phase of DMBA/TPA-induced skin tumorigenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Azadirachta; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Cytochromes b5; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Lipid Peroxidation; Liver; Male; Mice; Micronucleus Tests; Neoplasms, Experimental; Phytotherapy; Plant Extracts; Plant Leaves; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xenobiotics | 2013 |
Fermented Prunus mume with probiotics inhibits 7,12-dimethylbenz[a]anthracene and 12-o-tetradecanoyl phorbol-13-acetate induced skin carcinogenesis through alleviation of oxidative stress.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Cell Proliferation; Cell Transformation, Neoplastic; Diet; Female; Fermentation; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Oxidative Stress; Plant Preparations; Probiotics; Prunus; Skin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2013 |
Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Cell Proliferation; Cyclooxygenase 2; Female; Gene Expression Regulation, Neoplastic; Glucaric Acid; Humans; Interleukin-6; Mice; Mice, Inbred SENCAR; Phytochemicals; Resveratrol; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid | 2013 |
Structure-dependent inhibitory effects of synthetic cannabinoids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and skin tumour promotion in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cannabinoids; Cocarcinogenesis; Dermatitis, Contact; Female; Mice; Mice, Inbred ICR; Molecular Structure; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2013 |
Chemoprevention of skin cancer: effect of Lawsonia inermis L. (Henna) leaf powder and its pigment artifact, lawsone in the Epstein- Barr virus early antigen activation assay and in two-stage mouse skin carcinogenesis models.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Cutaneous; Administration, Oral; Animals; Antigens, Viral; Antineoplastic Agents, Phytogenic; B-Lymphocytes; Carcinogenesis; Cell Line, Tumor; Female; Herpesvirus 4, Human; Humans; Lawsonia Plant; Male; Naphthoquinones; Papilloma; Plant Extracts; Plant Leaves; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2013 |
Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Coculture Techniques; Culture Media, Conditioned; Disease Resistance; DNA Fragmentation; Fibroblasts; Fibrosarcoma; Humans; Liver Neoplasms; Mice; Mitochondrial Dynamics; Neoplasms; Rats; Spalax; Tetradecanoylphorbol Acetate; Tumor Stem Cell Assay | 2013 |
PD-1 blockage delays murine squamous cell carcinoma development.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cytokines; Female; Flow Cytometry; Immunoenzyme Techniques; Interferon-gamma; Mice; Mice, Inbred BALB C; Papilloma; Programmed Cell Death 1 Receptor; Tetradecanoylphorbol Acetate | 2014 |
Genome-wide screening of aberrant DNA methylation which associated with gene expression in mouse skin cancers.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Azacitidine; Cell Line, Tumor; Cell Transformation, Neoplastic; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred C57BL; Papilloma; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor AP-2 | 2015 |
Mast cells are dispensable for normal and activin-promoted wound healing and skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Activins; Animals; Carcinogens; Carcinoma, Squamous Cell; Chemotaxis; Female; Humans; Injections, Intralesional; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neovascularization, Pathologic; Neutrophil Infiltration; Papilloma; Proto-Oncogene Proteins c-kit; Recombinant Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wound Healing | 2013 |
Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line, Tumor; Enzyme Inhibitors; Farnesyltranstransferase; Gene Dosage; Gene Knock-In Techniques; Genes, ras; Humans; Mice, Mutant Strains; Mutation; Papilloma; Piperidines; Pyridines; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Assessment of Augmented Immune Surveillance and Tumor Cell Death by Cytoplasmic Stabilization of p53 as a Chemopreventive Strategy of 3 Promising Medicinal Herbs in Murine 2-Stage Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Apoptosis; Calendula; Carcinogenesis; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Chemoprevention; Eclipta; Female; Free Radicals; Immunologic Surveillance; Inflammation; Langerhans Cells; Mice; NF-kappa B; Phytotherapy; Plant Extracts; Proliferating Cell Nuclear Antigen; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trigonella; Tumor Suppressor Protein p53 | 2014 |
IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cytokines; Dendritic Cells; Female; Gene Expression Regulation; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Knockout; Papilloma; Signal Transduction; Skin Neoplasms; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate; Th1-Th2 Balance | 2014 |
IL-13 but not IL-4 signaling via IL-4Rα protects mice from papilloma formation during DMBA/TPA two-step skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cytokines; Interleukin-13 Receptor alpha1 Subunit; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Knockout; Papilloma; Receptors, Cell Surface; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2013 |
S100A9 has a protective role in inflammation-induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Calgranulin A; Calgranulin B; Carcinogenesis; Cell Transformation, Neoplastic; Dimerization; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Inflammation; Keratinocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Skin Neoplasms; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2014 |
Mast cells protect from skin tumor development and limit tumor growth during cutaneous de novo carcinogenesis in a Kit-dependent mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adoptive Transfer; Animals; Carcinogenesis; Cell Count; Cell Degranulation; Cytoprotection; Disease Models, Animal; Female; Granulocytes; Macrophages; Mast Cells; Mice; Proto-Oncogene Proteins c-kit; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Burden | 2014 |
Tumor promoter-induced sulfiredoxin is required for mouse skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcriptional Activation | 2014 |
DMBA/TPA treatment is necessary for BCC formation from patched deficient epidermal cells in Ptch(flox/flox)CD4Cre(+/-) mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alleles; Animals; Carcinogenesis; Carcinogens; Carcinoma, Basal Cell; CD4-Positive T-Lymphocytes; Disease Models, Animal; Epidermis; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mutation; Patched Receptors; Patched-1 Receptor; Proto-Oncogene Proteins p21(ras); Receptors, Cell Surface; Signal Transduction; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate | 2014 |
Chemomodulatory efficacy of lycopene on antioxidant enzymes and carcinogen-induced cutaneum carcinoma in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Carcinogens; Carotenoids; Chemoprevention; Female; Glutathione; Lipid Peroxidation; Lycopene; Mice, Inbred ICR; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Slit2 promotes tumor growth and invasion in chemically induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Basement Membrane; Blood Vessels; Bromodeoxyuridine; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Collagen Type IV; Humans; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Neoplasm Invasiveness; Nerve Tissue Proteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Burden | 2014 |
Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Communication; Cell Differentiation; Cell Transformation, Neoplastic; Cytokines; Dermatitis, Atopic; Disease Models, Animal; Epidermis; Keratinocytes; Membrane Proteins; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; NK Cell Lectin-Like Receptor Subfamily K; Papilloma; Permeability; Plakins; Protein Precursors; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymic Stromal Lymphopoietin; Time Factors | 2014 |
Chemopreventive effect of a novel, selective TACE inhibitor on DMBA- and TPA-induced skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; ADAM Proteins; ADAM17 Protein; Animals; Antineoplastic Agents; Cocarcinogenesis; Cytokines; Dose-Response Relationship, Drug; Edema; Female; Hydroxamic Acids; Mice, Inbred BALB C; Pyrrolidinones; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Apoptotic effect of pheophorbide a-mediated photodynamic therapy on DMBA/TPA-induced mouse papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogenesis; Caspase 3; Chlorophyll; Female; Immunohistochemistry; In Situ Nick-End Labeling; Mice, Hairless; Papilloma; Photochemotherapy; Photosensitizing Agents; Proliferating Cell Nuclear Antigen; Tetradecanoylphorbol Acetate | 2015 |
Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adult Stem Cells; Animals; Carcinogens; Carcinoma; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Disease Progression; Gene Expression Regulation, Neoplastic; Hair Follicle; Homeodomain Proteins; Keratinocytes; Mice; Mice, Transgenic; Multipotent Stem Cells; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Papilloma; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
In vivo long-term effects of retinoic acid exposure in utero on induced tumours in adult mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Squamous Cell; Drug Administration Schedule; Female; Keratoacanthoma; Male; Mice; Papilloma; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Treatment Outcome; Tretinoin | 2014 |
Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Cell Proliferation; Cyclooxygenase 2; Eicosanoids; Epidermis; Epithelial Cells; Gene Deletion; Gene Targeting; Hyperplasia; Keratinocytes; Lipid Metabolism; Macrophages; Mice; Myeloid Cells; Papilloma; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Genome-wide analysis of DNA methylation in UVB- and DMBA/TPA-induced mouse skin cancer models.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; CpG Islands; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Genome; Inflammation; Mice; Sequence Analysis, DNA; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2014 |
Photodynamic therapy using a novel irradiation source, LED lamp, is similarly effective to photodynamic therapy using diode laser or metal-halide lamp on DMBA- and TPA-induced mouse skin papillomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Female; Lasers, Semiconductor; Mice; Mice, Hairless; Papilloma; Photochemotherapy; Photosensitizing Agents; Porphyrins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Cells of origin in skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinoma, Basal Cell; CD4-Positive T-Lymphocytes; Epidermis; Patched Receptors; Receptors, Cell Surface; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Topical (+)-catechin emulsified gel prevents DMBA/TPA-induced squamous cell carcinoma of the skin by modulating antioxidants and inflammatory biomarkers in BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Acacia; Administration, Topical; Animals; Antioxidants; Biomarkers; Carcinoma, Squamous Cell; Catechin; Dinoprostone; Drug Evaluation, Preclinical; Emulsions; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Plant Extracts; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2014 |
Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Nucleus; Dual-Specificity Phosphatases; Extracellular Signal-Regulated MAP Kinases; Genes, ras; Mice; Mice, Knockout; Plasminogen Activator Inhibitor 2; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2014 |
Soluble endoglin antagonizes Met signaling in spindle carcinoma cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Carcinogenesis; Cell Movement; Cell Proliferation; DNA, Complementary; Endoglin; Enzyme Activation; Female; HEK293 Cells; Hepatocyte Growth Factor; Humans; MAP Kinase Signaling System; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Prognosis; Proto-Oncogene Proteins c-met; Receptors, Cell Surface; Sarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transfection; Transforming Growth Factor beta1; Tumor Cells, Cultured | 2015 |
Riboflavin as adjuvant with cisplatin: study in mouse skin cancer model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Antioxidants; Body Weight; Carcinoma, Squamous Cell; Cisplatin; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Glutathione; Kidney; Liver; Male; Malondialdehyde; Mice; Photosensitizing Agents; Random Allocation; Riboflavin; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
Mouse models of nonmelanoma skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Culture Techniques; DNA; Epidermis; Humans; Keratinocytes; Mice; Skin Neoplasms; Staining and Labeling; Tamoxifen; Tetradecanoylphorbol Acetate | 2015 |
14-3-3σ regulates keratinocyte proliferation and differentiation by modulating Yap1 cellular localization.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Active Transport, Cell Nucleus; Adaptor Proteins, Signal Transducing; Animals; Cell Cycle Proteins; Cell Differentiation; Cell Nucleus; Cell Proliferation; Cytoplasm; Epidermis; Gene Expression Regulation; Heterozygote; Homozygote; Keratinocytes; Lentivirus; Mice; Phenotype; Phosphoproteins; Protein Isoforms; RNA, Small Interfering; Skin; Tetradecanoylphorbol Acetate; YAP-Signaling Proteins | 2015 |
TGF-β promotes heterogeneity and drug resistance in squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cisplatin; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Glutathione; Head and Neck Neoplasms; Heterografts; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplastic Stem Cells; NF-E2-Related Factor 2; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta | 2015 |
Conditional disruption of rictor demonstrates a direct requirement for mTORC2 in skin tumor development and continued growth of established tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Carrier Proteins; Caspase 3; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Chemoprevention; Keratinocytes; Mechanistic Target of Rapamycin Complex 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multiprotein Complexes; Proto-Oncogene Proteins c-akt; Rapamycin-Insensitive Companion of mTOR Protein; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases; Ultraviolet Rays | 2015 |
A murine model for the development of melanocytic nevi and their progression to melanoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Line, Tumor; Cell Separation; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Disease Progression; Melanoma; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Nevus, Pigmented; ras Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Cancer-promoting effect of capsaicin on DMBA/TPA-induced skin tumorigenesis by modulating inflammation, Erk and p38 in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Capsaicin; Carcinogenesis; Cyclooxygenase 2; Female; Hyperplasia; Inflammation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2015 |
Caspase-3 promotes genetic instability and carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Marrow Cells; Breast; Caspase 3; Cells, Cultured; Endodeoxyribonucleases; Epithelial Cells; Female; Genome; Genomic Instability; Humans; Mice; Neoplasms, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
Crosstalk between Desmoglein 2 and Patched 1 accelerates chemical-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Division; Cocarcinogenesis; Dermis; Desmoglein 2; Epidermis; Gene Knock-In Techniques; Genes, Reporter; Genetic Predisposition to Disease; Genotype; Hair Follicle; Hedgehog Proteins; Hyperplasia; Keratinocytes; Mice; Mice, Transgenic; Papilloma; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; Signal Transduction; Skin Neoplasms; Stromal Cells; Tetradecanoylphorbol Acetate; Time Factors | 2015 |
Chemopreventive efficacy of menthol on carcinogen-induced cutaneous carcinoma through inhibition of inflammation and oxidative stress in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma; Chemoprevention; Cyclooxygenase 2; Dermatitis; Female; Glutathione; Inflammation; Menthol; Mice, Inbred ICR; Neoplasms, Experimental; Oxidative Stress; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
Twist1 regulates keratinocyte proliferation and skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Cycle; Cell Proliferation; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Keratinocytes; Mice; Mice, Transgenic; Nuclear Proteins; Promoter Regions, Genetic; Skin Neoplasms; Tetradecanoylphorbol Acetate; Twist-Related Protein 1 | 2016 |
Resistance of R-Ras knockout mice to skin tumour induction.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cell Proliferation; Dermis; Genetic Association Studies; Genetic Predisposition to Disease; Mice, Inbred C57BL; Mice, Knockout; Papilloma; ras Proteins; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2015 |
Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; Carcinoma, Verrucous; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; Disease Progression; DNA Transposable Elements; Female; Humans; Mice; Mice, Transgenic; Mouth Neoplasms; Mutagenesis, Insertional; Neoplasm Invasiveness; Oncogenes; Papilloma; Papillomaviridae; Receptor, Notch1; Skin Neoplasms; Specific Pathogen-Free Organisms; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Virus Infections; Uterine Cervical Neoplasms | 2015 |
Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Cytochrome P-450 CYP2E1; DNA Damage; Hair Follicle; Keratinocytes; Mice; Mice, Knockout; NFATC Transcription Factors; Papilloma; Skin; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate | 2015 |
Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Cell Survival; Female; Male; Mice; Mice, Knockout; Mice, Transgenic; Protein Kinase C-epsilon; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 2016 |
Low dose triterpene-quinone fraction from Ardisia crispa root precludes chemical-induced mouse skin tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anticarcinogenic Agents; Ardisia; Cell Transformation, Neoplastic; Chemical Fractionation; Chemoprevention; Curcumin; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Male; Mice; Mice, Inbred ICR; Plant Extracts; Plant Roots; Quinones; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Triterpenes | 2015 |
Deletion of 14-3-3σ sensitizes mice to DMBA/TPA-induced papillomatosis.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Cell Differentiation; Cell Proliferation; Codon, Nonsense; Disease Models, Animal; Down-Regulation; Epidermal Cells; Epidermis; Exons; Female; Gain of Function Mutation; Gene Deletion; Hair Follicle; Heterozygote; Immunohistochemistry; Integrases; Keratinocytes; Male; Mice; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Pro-Oxidant Role of Silibinin in DMBA/TPA Induced Skin Cancer: 1H NMR Metabolomic and Biochemical Study.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Catalase; In Situ Nick-End Labeling; Magnetic Resonance Spectroscopy; Male; Metabolomics; Mice; Reactive Oxygen Species; Silybin; Silymarin; Skin Neoplasms; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2016 |
Sex differences and pathology status correlated to the toxicity of some common carcinogens in experimental skin carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Disease Models, Animal; Female; Male; Mice; Mice, Hairless; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Administration of resveratrol enhances cell-cycle arrest followed by apoptosis in DMBA-induced skin carcinogenesis in male Wistar rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Carcinogenesis; Cell Cycle Checkpoints; Male; Rats; Rats, Wistar; Resveratrol; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate | 2016 |
Elevated VEGF-D Modulates Tumor Inflammation and Reduces the Growth of Carcinogen-Induced Skin Tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Flow Cytometry; Lymph Nodes; Lymphangiogenesis; Lymphatic Metastasis; Lymphatic Vessels; Lymphocyte Count; Macrophages; Mast Cells; Mice; Mice, Knockout; Polymerase Chain Reaction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor D | 2016 |
Panx3 links body mass index and tumorigenesis in a genetically heterogeneous mouse model of carcinogen-induced cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Mass Index; Carcinogenesis; Carcinogens; Connexins; Crosses, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Genetic Predisposition to Disease; Humans; Inflammation; Lipid Metabolism; Male; Mice; Mice, Inbred Strains; Quantitative Trait Loci; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
Elevated ΔNp63α Levels Facilitate Epidermal and Biliary Oncogenic Transformation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bile Duct Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Cellular Senescence; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphoproteins; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Trans-Activators | 2017 |
Suppression of skin tumorigenesis in CD109-deficient mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, CD; Apoptosis; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; DNA Damage; Genes, ras; Genetic Predisposition to Disease; Keratinocytes; Mice, Knockout; Mutation; Neoplasm Proteins; NF-E2-Related Factor 2; Papilloma; Phenotype; Phosphorylation; Signal Transduction; Skin Neoplasms; Smad2 Protein; Tetradecanoylphorbol Acetate; Time Factors; Transforming Growth Factor beta1 | 2016 |
Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Proliferation; Cyclin D1; Daucus carota; G1 Phase; Humans; Keratinocytes; Male; Mice; Mice, Inbred BALB C; Protective Agents; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2017 |
E1a is an exogenous in vivo tumour suppressor.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenovirus E1A Proteins; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Female; HCT116 Cells; Humans; Melanoma, Experimental; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Burden; Tumor Suppressor Proteins | 2017 |
Folic Acid Modulates DMBA/TPA-Induced Changes in Skin of Mice: A Study Relevant to Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Epidermis; Folic Acid; Mice; Mice, Inbred BALB C; Ornithine Decarboxylase; Proliferating Cell Nuclear Antigen; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin B Complex | 2018 |
Constitutive transgene expression of Stem Cell Antigen-1 in the hair follicle alters the sensitivity to tumor formation and progression.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antigens, Ly; Carcinogenesis; Clone Cells; Colony-Forming Units Assay; Disease Progression; Female; Hair Follicle; Integrases; Membrane Proteins; Mice, Inbred C57BL; Mice, Transgenic; Morphogenesis; Skin; Tetradecanoylphorbol Acetate; Transgenes | 2017 |
PAD2 overexpression in transgenic mice augments malignancy and tumor-associated inflammation in chemically initiated skin tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Disease Progression; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Male; Mice; Mice, Transgenic; Papilloma; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Up-Regulation | 2017 |
Annona muricata leaves extracts prevent DMBA/TPA-induced skin tumorigenesis via modulating antioxidants enzymes system in ICR mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Annona; Antioxidants; Carcinogenesis; Furans; Lactones; Male; Mice, Inbred ICR; Plant Extracts; Plant Leaves; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2017 |
Dendrimer conjugated estramustine nanocrystalline 'Dendot': An effective inhibitor of DMBA-TPA induced papilloma formation in mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Cell Proliferation; Dendrimers; Estramustine; Female; Intestines; Kidney; Liver; Mice; Nanoparticles; Papilloma; Skin Neoplasms; Stomach; Tetradecanoylphorbol Acetate | 2017 |
Ingenol-3-Angelate Suppresses Growth of Melanoma Cells and Skin Tumor Development by Downregulation of NF-κB-Cox2 Signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Apoptosis Regulatory Proteins; Carcinogenesis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2; Diterpenes; Down-Regulation; Epidermis; Female; Hyperplasia; Inflammation; Melanoma; Mice, Inbred ICR; NF-kappa B; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2018 |
Intense Pulsed Light: Friend or Foe? Molecular Evidence to Clarify Doubts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Carcinogens; Disease Models, Animal; Female; Glycolysis; Intense Pulsed Light Therapy; Keratins; Mice; Mice, Inbred ICR; Oxidative Stress; Random Allocation; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2018 |
A novel tubulin inhibitor STK899704 induces tumor regression in DMBA/TPA-induced skin carcinogenesis model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antimetabolites, Antineoplastic; Benzofurans; Carcinogenesis; Colchicine; Disease Models, Animal; Fluorouracil; Male; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tubulin; Tubulin Modulators | 2018 |
Salidroside prevents skin carcinogenesis induced by DMBA/TPA in a mouse model through suppression of inflammation and promotion of apoptosis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Cytokines; Drug Administration Schedule; Gene Expression Regulation, Neoplastic; Glucosides; Humans; Mice; Phenols; Random Allocation; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2018 |
Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Lineage; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Clonal Evolution; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Genetic Predisposition to Disease; Male; Mice, Transgenic; Mutation; Neoplasms, Experimental; Phenotype; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tumor Burden | 2018 |
TRP63/TP63 loss accelerates skin tumorigenesis through activation of Wnt/β-catenin signaling.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Mice, Knockout; Mice, Nude; Phosphoproteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Trans-Activators; Transcription Factors; Tumor Burden; Tumor Suppressor Proteins; Wnt Signaling Pathway | 2018 |
C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, Lethal; Keratinocytes; Mice; Mice, Knockout; ras Proteins; Receptors, Death Domain; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 2018 |
Bone marrow-derived epithelial cells and hair follicle stem cells contribute to development of chronic cutaneous neoplasms.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Bone Morphogenetic Protein 5; Cell Movement; Cell Plasticity; Cell Transformation, Neoplastic; Coculture Techniques; Epithelial Cells; Female; Hair Follicle; HMGB1 Protein; Keratinocytes; Keratins; Male; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Papilloma; Skin Neoplasms; Stem Cells; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2018 |
Pre-Exposure to Chronic Unpredictable Stress Suppresses the Chemopreventive Potential of Aloe Vera (Av) Leaf Gel Against 7,12-Dimethylbenz(a)anthracene (DMBA) Induced Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Carcinogens; Chemoprevention; Male; Mice; Plant Preparations; Random Allocation; Skin Neoplasms; Stress, Physiological; Tetradecanoylphorbol Acetate | 2019 |
[Role of clock proteins in skin carcinogenesis in 14-month-old SHR mice maintained under disrupted light regimen].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; ARNTL Transcription Factors; Cell Transformation, Neoplastic; CLOCK Proteins; Cryptochromes; Gene Expression Regulation, Neoplastic; Lighting; Male; Mice; Neoplasm Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2016 |
XB130 deficiency enhances carcinogen-induced skin tumorigenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adaptor Proteins, Signal Transducing; Animals; Carcinogenesis; Carcinogens; Cell Proliferation; Female; Genes, Tumor Suppressor; Inflammation; Male; Mice; Mice, Knockout; Microfilament Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2019 |
Modulation of cancer signalling pathway(s) in two -stage mouse skin tumorigenesis by annonacin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogenesis; Carcinogens; Female; Furans; Kidney; Lactones; Liver; Mice; Mice, Inbred ICR; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2019 |
Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA).
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Female; Humans; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2019 |
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carcinogens; Cell Line; Cytokines; Female; Flavonoids; Mice, Inbred ICR; RNA, Small Interfering; Shc Signaling Adaptor Proteins; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription Factor RelA | 2020 |
Pivotal Involvement of the CX3CL1-CX3CR1 Axis for the Recruitment of M2 Tumor-Associated Macrophages in Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Movement; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Humans; Male; Mice; Mice, Inbred C57BL; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tumor-Associated Macrophages; Wnt3A Protein | 2020 |
β-Elemene inhibits 7,12-dimethylbenz(a)anthracene/12-O-tetradecanoylphorbol-13-acetate-induced skin tumorigenesis through suppression of NF-κB-associated signaling events in the mouse skin model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Disease Models, Animal; Mice; NF-kappa B; Sesquiterpenes; Signal Transduction; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2020 |
Integrin α3β1 Is a Key Regulator of Several Protumorigenic Pathways during Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Epidermis; Humans; Integrin alpha3beta1; Kalinin; Keratinocytes; Mice; Neoplasms, Experimental; Signal Transduction; Skin Neoplasms; Spheroids, Cellular; Tetradecanoylphorbol Acetate; Tetraspanin 24 | 2021 |
Targeting 14-3-3ε activates apoptotic signaling to prevent cutaneous squamous cell carcinoma.
Topics: 14-3-3 Proteins; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; cdc25 Phosphatases; Cell Line, Tumor; Cytoplasm; Female; Humans; Keratinocytes; Male; Mice; Mice, Knockout; Neoplasms, Experimental; Protein Multimerization; Skin Neoplasms; Tetradecanoylphorbol Acetate; Xenograft Model Antitumor Assays | 2021 |
Regulatory T Cells Play an Important Role in the Prevention of Murine Melanocytic Nevi and Melanomas.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; CD4 Antigens; CD8 Antigens; Female; Humans; Immune Tolerance; Male; Melanoma, Experimental; Mice; Mice, Knockout; Nevus, Pigmented; Skin; Skin Neoplasms; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 2021 |
3'-Hydroxypterostilbene Inhibits 7,12-Dimethylbenz[a]anthracene (DMBA)/12-O-Tetradecanoylphorbol-13-Acetate (TPA)-Induced Mouse Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Carcinogens; Cyclooxygenase 2; Drug Eruptions; Female; Gene Expression Regulation; Humans; Keratinocytes; Mice, Inbred ICR; Ornithine Decarboxylase; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate | 2021 |
Analyzing skin tumor development in mice by the DMBA/TPA model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Humans; Mice; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2021 |
Gene Deletion of Microsomal Prostaglandin E Synthase-1 Suppresses Chemically Induced Skin Carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Cyclooxygenase 2; Cytokines; Dinoprostone; Mice; Mice, Inbred BALB C; Prostaglandin-E Synthases; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2021 |
Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR-ERBB2 pathway.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aged; Animals; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; ErbB Receptors; Female; Homeodomain Proteins; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Grading; Receptor, ErbB-2; Signal Transduction; Skin Neoplasms; Survival Rate; Tetradecanoylphorbol Acetate; Transcription Factors | 2021 |
DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; CCAAT-Enhancer-Binding Protein-beta; Cell Cycle Checkpoints; Cell Proliferation; Cellular Senescence; DNA Methylation; Epigenesis, Genetic; Female; Fibroblasts; HEK293 Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Interleukin-1alpha; Membrane Proteins; Mice; Microscopy, Fluorescence; Papilloma; Phenotype; Secretory Pathway; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2021 |
IL-13Rα1 Suppresses Tumor Progression in Two-Stage Skin Carcinogenesis Model by Regulating Regulatory T Cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Interleukin-13; Interleukin-13 Receptor alpha1 Subunit; Mice; Mice, Knockout; Papilloma; Skin Neoplasms; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 2022 |
P2RY6 Has a Critical Role in Mouse Skin Carcinogenesis by Regulating the YAP and β-Catenin Signaling Pathways.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Catenin; Carcinogenesis; Hyperplasia; Keratinocytes; Mice; Receptors, Purinergic P2; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Wnt Signaling Pathway; YAP-Signaling Proteins | 2022 |
Isolation of cancer stem cells from skin squamous cell carcinoma.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Disease Models, Animal; Humans; Mice; Neoplastic Stem Cells; Papilloma; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2022 |