tetradecanoylphorbol acetate has been researched along with 1-hexadecyl-2-acetyl-glycero-3-phosphocholine in 291 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 79 (27.15) | 18.7374 |
| 1990's | 183 (62.89) | 18.2507 |
| 2000's | 24 (8.25) | 29.6817 |
| 2010's | 5 (1.72) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L | 1 |
| Kübler, W; Neumann, FJ; Ott, I; Rauch, B; Richardt, G; Tillmanns, H; Zimmermann, R | 1 |
| Filep, JG; Földes-Filep, E; Sirois, P | 1 |
| Fassbender, M; Haller, H; Kaiser, D; Lode, H; Rau, M; Schaberg, T | 1 |
| Bach, MK; Brashler, JR; Petzold, EN; Sanders, ME | 1 |
| Dubyak, GR; el-Moatassim, C | 1 |
| Cramer, R; Knowles, A; Menegazzi, R; Patriarca, P; Zabucchi, G | 1 |
| Edwards, YS; Hii, CS; Murray, AW | 1 |
| Fernandez-Gallardo, S; Guntaka, RV; Kandala, JC; Lim, RW; Shukla, SD; Tripathi, YB | 1 |
| Joseph, S; MacDermot, J | 1 |
| Dailey, LA; Devlin, RB; Friedman, M; McKinnon, K; Noah, TL; Samet, JM; Yankaskas, JR | 1 |
| Blackburn, WD; Chatham, WW; Heck, LW | 1 |
| Carey, F; Flower, RJ; Forder, RA; Murphy, CT; Peers, SH; Westwick, J | 1 |
| Emeis, JJ; Tranquille, N | 1 |
| Tatarintsev, AV; Varfolomeyev, SD; Vrzheshch, PV; Yershov, DE | 1 |
| Hammond, GL; Nelson, PJ; Peyman, JA | 1 |
| Cheung, PY; Kucey, DS; Rotstein, OD | 1 |
| Chao, W; Hanahan, DJ; Liu, H; Olson, MS | 2 |
| Murphy, CT; Westwick, J | 1 |
| Arata, Y; Kume, S; Tada, S; Ui, M; Yatomi, Y | 1 |
| Adams, DO; Sebaldt, RJ; Uhing, RJ | 1 |
| Ackley, NJ; Adler, KB; Crapo, JD; Kinnula, VL | 1 |
| Kantorski, J; Tchórzewski, H | 1 |
| Levine, L | 2 |
| Becker, EL; Huang, CK; Molski, TF; Sha'afi, RI; Stevens, T; Yamazaki, M | 1 |
| Balsinde, J; Mollinedo, F | 1 |
| Ferro, TJ; Hocking, DC; Johnson, A | 1 |
| Bosia, A; Bussolino, F; Garbarino, G; Ghigo, D; Heller, R; Pescarmona, G; Till, U | 1 |
| Gay, JC; Murray, JJ | 1 |
| Elmore, M; Kellie, S; Murphy, CT; Westwick, J | 1 |
| Distler, A; Haller, H; Lindschau, C; Lode, H; Schaberg, T | 1 |
| Chang, FY; Chang, ML; Chou, CT; Shaio, MF | 1 |
| Harris, T; Stewart, AG | 1 |
| Chau, LY | 1 |
| Hayashi, H; Inoue, K; Kudo, I; Nojima, S | 1 |
| Kozyukov, AV; Makarova, OV; Porodenko, NV; Pustynnikov, MG; Severin, ES; Sokolovsky, AA | 1 |
| de Nicolas, R; Egido, J; Gonzalez, E; Hernando, P | 1 |
| Blom, M; Koenderman, L; Kuijpers, TW; Roos, D; Tool, AT; Verhoeven, AJ | 1 |
| Foreman, JC; Hayes, NA; McLeod, J | 1 |
| Bosia, A; Bussolino, F; Garbarino, G; Ghigo, D; Heller, R; Pescarmona, G; Schröder, H; Till, U | 1 |
| Cramer, R; Dri, P; Patriarca, P; Romano, M; Spessotto, P | 1 |
| Korth, R; Middeke, M | 1 |
| Hayashi, M; Imai, Y; Oh-ishi, S | 1 |
| Benveniste, J; Galanaud, P; Leprince, C; Richard, Y; Thomas, Y; Treton, D; Vivier, E | 1 |
| Anderson, GP; Hultkvist-Bengtsson, U; Kings, M; Morley, J | 1 |
| Häyry, P; Mattila, P; Renkonen, R; Turunen, JP | 1 |
| Elstad, MR; McIntyre, TM; Prescott, SM; Zimmerman, GA | 2 |
| Fernandez-Gallardo, S; Garcia, C; Garcia, MC; Gijon, MA; Mollinedo, F; Sanchez Crespo, M | 1 |
| Hagenlocker, BE; Walker, BA; Ward, PA | 1 |
| García-Sáinz, JA; Gutiérrez-Venegas, G | 1 |
| Geffner, JR; Isturiz, MA; Lazzari, MA; Schattner, MA | 1 |
| Bidault, J; Breton, M; Colard, O; Ninio, E | 1 |
| Baglioni, C; Bussolino, F; Camussi, G; Herrick-Davis, K | 1 |
| Guntaka, RV; Kandala, JC; Lim, RW; Shukla, SD; Tripathi, YB | 1 |
| Gay, JC | 2 |
| Fontán, PA; Geffner, JR; Isturiz, MA; Sordelli, DO | 1 |
| Baldi, E; Cirino, NM; Kester, M; McFadden, ER; Panuska, JR; Villani, A | 1 |
| Baggiolini, M; Dahinden, CA; Deranleau, DA; Kernen, P; Spry, CJ; Tai, PC; von Tscharner, V; Wymann, MP | 1 |
| Di Virgilio, F; Picello, E; Pizzo, P | 1 |
| Salari, H; Wong, A | 1 |
| Gimbrone, MA; Hrbolich, JK; Schafer, AI; Zavoico, GB | 1 |
| Champeix, P; Favier, R; Hurtaud, MF; Kaplan, C; Lecompte, T; Morel, MC; Potevin, F; Samama, M; Schlegel, N | 1 |
| Béréziat, G; Cherqui, G; Etienne, J; Kadiri, C; Masliah, J; Rybkine, T | 1 |
| Bonavida, B; Braquet, P; Mencia-Huerta, JM | 2 |
| Edwards, RJ; MacDermot, J; Storch, J | 1 |
| Benveniste, J; Bessou, G; Bossant, MJ; Joly, F; Ninio, E; Vigrain, I | 1 |
| Lerner, R; Lindström, P; Palmblad, J | 2 |
| Hirst, JJ; Jenkin, G; Rice, GE; Thorburn, GD | 1 |
| DiPersio, JF; Gasson, JD; Golde, DW | 1 |
| Barnes, PJ; Giembycz, MA; Kroegel, C | 1 |
| Halenda, SP; Rehm, AG | 1 |
| Demos, M; Duronio, V; Howard, S; Pelech, SL; Salari, H | 1 |
| Adams, DO; Hollenbach, PW; Prpic, V; Sebaldt, RJ; Uhing, RJ | 1 |
| Tai, HH; Tanizawa, H | 1 |
| Chap, H; Lumb, RH; Pool, GL; Record, M; Ribbes, G; Terce, F | 1 |
| Gandhi, CR; Hanahan, DJ; Olson, MS | 1 |
| Bertoli, E; Curatola, G; Fiorini, R; Giorgi, PL; Kantar, A | 1 |
| Atkins, PC; Moskovitz, AR; Taylor, MB; von Allmen, C; Zweiman, B | 1 |
| Bonak, VA; Caon, AC; Gaudry, M; Gilbert, C; Huang, CK; McColl, SR; Naccache, PH; Umezawa, K | 1 |
| Huu, TP; Perianin, A; Stanislawski, L | 1 |
| Barnes, PJ; Chanez, P; Chung, KF; Dent, G; Yukawa, T | 1 |
| Hayashi, M; Oh-ishi, S; Qu, XF; Yamaki, K | 1 |
| Midorikawa, Y; Ogata, H | 1 |
| Johnson, HM; Torres, BA | 1 |
| Altukhova, IP; Avdonin, PV | 1 |
| Avdonin, PV; Boogry, EM; Cheglakov, IB; Mazaev, AV; Svitina-Ulitina, IV; Tkachuk, VA | 1 |
| Molski, TF; Sha'afi, RI; Tao, W | 1 |
| Wey, HE | 1 |
| Masuzawa, Y; Ojima-Uchiyama, A; Sugiura, T; Waku, K | 1 |
| de la Motte, CA; DiCorleto, PE | 1 |
| Gudgeon, JR; Martin, W | 1 |
| Kariya, T; Kume, S; Matsumoto, Y; Ozaki, Y; Yatomi, Y | 1 |
| Dhar, A; Morrison, WJ; Shukla, SD | 2 |
| Jacobson, DP; O'Flaherty, JT; Redman, JF | 1 |
| Avdonin, PV; Svitina-Ulitina, IV; Tkachuk, VA | 1 |
| Becker, EL; Durstin, M; Gomez-Cambronero, J; Molski, TF; Sha'afi, RI; Yamazaki, M | 1 |
| Bachelet, M; Béréziat, G; Kadiri, C; Masliah, J; Vargaftig, BB | 1 |
| Jacobson, D; O'Flaherty, JT | 1 |
| Evans, AT; Evans, FJ; Formukong, EA | 1 |
| Hayashi, I; Hayashi, M; Oh-ishi, S; Utsunomiya, I; Yamaki, K | 1 |
| McIntyre, TM; Nelson, P; Parker, CJ; Prescott, SM; Stevens, DL; Whatley, RE; Zimmerman, GA | 1 |
| Adams, DO; Hollenbach, PW; Prpic, V; Uhing, RJ | 1 |
| Benveniste, J; Bessou, G; Bossant, MJ; Joly, F; Leyravaud, S; Ninio, E | 1 |
| Chap, H; Gelas, P; Record, M; Ribbes, G; Terce, F | 1 |
| Bhalla, RC; Fisher, RA; Sharma, RV | 1 |
| Becker, AB; Brandes, LJ; Gerrard, JM; McNicol, A; Saxena, SP | 1 |
| McIntyre, TM; Prescott, SM; Reinhold, SL; Zimmerman, GA | 1 |
| Nieto, ML; Sanchez Crespo, M; Velasco, S | 1 |
| Hanahan, DJ; Homma, H | 1 |
| Downes, CP; Huang, SJ; Monk, PN; Whetton, AD | 1 |
| Clay, KL; Guthrie, LA; Johnston, RB; Seccombe, JF; Worthen, GS | 1 |
| Jacobson, D; O'Flaherty, JT; Redman, J | 1 |
| Baggiolini, M; Thelen, M; Wolf, M | 1 |
| Grinstein, S; Nasmith, PE | 1 |
| Ferber, E; Munder, PG; Storch, J | 1 |
| Agrawal, DK; Tamura, N; Townley, RG | 1 |
| Justen, JM; Sam, LM; Smith, RJ | 1 |
| Colton, CA; Gilbert, DL | 1 |
| Camoratto, AM; Grandison, L | 1 |
| Bühler, FR; Dimitrov, D; Resink, TJ; Stucki, S | 1 |
| Drummond, AH; MacIntyre, DE; McNicol, A | 1 |
| Grewal, IS; Lad, PM; Olson, CV | 2 |
| Becker, EL; Molski, MM; Naccache, PH; Sha'afi, RI; Volpi, M | 1 |
| Beckman, JK; Gay, JC; Lukens, JN; Zaboy, KA | 1 |
| Friesen, LL; Gerrard, JM; Israels, SJ; McCrea, JM; Robinson, P | 1 |
| Niwa, Y; Ohashi, T; Ozaki, Y | 2 |
| Becker, EL; Loew, L; Molski, MM; Molski, TF; Naccache, PH; Sha'afi, RI; Shefcyk, J; Volpi, M | 1 |
| Nishihira, J; O'Flaherty, JT | 1 |
| Becker, EL; Kanaho, Y; Matsumoto, T; Molski, TF; Sha'afi, RI | 1 |
| Molski, TF; Sha'afi, RI | 1 |
| Bitter-Suermann, D; Englberger, W; Hadding, U | 1 |
| Grigorian, GY; Ryan, US | 1 |
| Baggiolini, M; Deranleau, DA; von Tscharner, V; Wymann, MP | 1 |
| Fuse, I; Hanano, M; Hattori, A; Higashihara, M; Koike, T; Nagayama, R; Shibata, A; Takahashi, H; Takeshige, T; Takizawa, S | 1 |
| Daniel, LW; Waite, M; Wykle, RL | 1 |
| Alexandre, A; Deana, R; Doni, MG; Padoin, E | 1 |
| Joseph, S; Kakkar, VV; Krishnamurthi, S | 1 |
| Cerutti, P; Emerit, I; Jörg, A; Kozumbo, WJ; Muehlematter, D | 1 |
| Ho, YS; Lee, WM; Snyderman, R | 1 |
| Bochner, BS; Brown, KE; Peachell, PT; Schleimer, RP | 1 |
| Maclouf, J; Pradelles, P; Robidoux, C; Sirois, P | 1 |
| O'Flaherty, JT; Rossi, AG; Thomas, MJ | 1 |
| Gay, JC; Stitt, ES | 1 |
| Schwertschlag, US; Whorton, AR | 1 |
| Johnson, B; Valone, FH | 1 |
| Dozen, M; Hayashi, M; Imai, Y; Kimura, J; Oh-ishi, S; Suwabe, Y; Yamaki, K | 1 |
| Katabami, F; Matsumiya, H; Matsuno, K | 1 |
| Hanahan, DJ; Sugatani, J | 1 |
| Hardisty, RM; Powling, MJ | 1 |
| Hayashi, M; Nomura, H; Oh-ishi, S; Tsushima, S; Yamaki, K | 1 |
| García-Sáinz, JA; Hernández-Sotomayor, SM | 1 |
| Thomson, DM | 1 |
| Lees, CJ; McCall, CE; O'Flaherty, JT; Shewmake, T; Thomas, MJ; Wykle, RL | 1 |
| Hammett, MJ; Love, SH; McCall, CE; O'Flaherty, JT; Shewmake, TB; Thomas, MJ; Wykle, RL | 1 |
| McCall, CE; O'Flaherty, JT; Schmitt, JD; Wykle, RL | 1 |
| Bussolino, F; Camussi, G; Ghezzo, F; Pegoraro, L | 1 |
| Marignani, PA; Sebaldt, RJ | 1 |
| Aglietta, M; Arese, M; Bussolino, F; Camussi, G; Costamagna, C; Garbarino, G; Pescarmona, G; Sanavio, F; Silvagno, F; Soldi, R | 1 |
| Horie, S; Kita, H | 1 |
| Ortega, G; Parker, L; Shearer, WT; Smith, CS | 1 |
| Buurman, WA; von Asmuth, EJ | 1 |
| Bodlaj, R; Glaubitt, SI; Hübner, C; Krombach, F; Lehr, HA; Messmer, K; Münzing, S; Seiffge, D; von Andrian, UH | 1 |
| Padgett, EL; Pruett, SB | 1 |
| Ahmed, K; Campbell, KD; Skubitz, AP; Skubitz, KM | 1 |
| Fortier, MA; Kim, JJ | 1 |
| Jacquier-Sarlin, MR; Kantengwa, S; Maridonneau-Parini, I; Polla, BS; Stubbe, H | 1 |
| Filep, JG; Földes-Filep, E; Fournier, A | 1 |
| Liu, B; Nakashima, S; Nozawa, Y; Shimizu, T; Takano, T | 1 |
| Bratton, DL | 1 |
| Bousseau, A; Fauci, AS; Poli, G; Weissman, D | 1 |
| Kellie, S; Murphy, CT; Westwick, J | 1 |
| Chung, D; Gravel, S; Powell, WS | 1 |
| Turner, NC; Wood, LJ | 1 |
| Chen, XS; Funk, CD; Griffis, G; Kurre, U | 1 |
| Bratt, J; Lerner, R; Palmblad, J; Ringertz, B | 1 |
| Colotta, F; Fadlon, EJ; Mantovani, A; Matteucci, C; Orlando, S; Sozzani, S | 1 |
| Betz, R; Jany, B; Schreck, R | 1 |
| Ishii, S; Izumi, T; Kato, S; Mutoh, H; Shimizu, T | 1 |
| Dohi, T; Kitayama, S; Morita, K; Okamoto, H; Shibata, K; Shirakawa, M | 1 |
| Abe, T; Matsuda, K; Nagai, H; Omata, T; Segawa, Y; Yoshida, K | 1 |
| Berg, A; Le Blanc, K; Palmblad, J; Samuelsson, J | 1 |
| Parker, L; Shearer, WT; Smith, CS | 1 |
| Barnes, PJ; Giembycz, MA; Kroegel, C; Matthys, H; Westwick, J | 1 |
| Daniels, RH; Elmore, MA; Finnen, MJ; Hill, ME; Lackie, JM; Shimizu, Y | 1 |
| Blackburn, WD; Chatham, WW; Turkiewicz, A | 1 |
| Bonney, RJ; Chilton, FH; Darling, IM; Davern, LB; Franson, RC; Havens, MB; Nettleton, DO; Stanley, PL; Tramposch, KM | 1 |
| Ferby, IM; Kume, K; Sakanaka, C; Shimizu, T; Waga, I | 1 |
| Larivée, P; Levine, SJ; Logun, C; Martinez, A; Shelhamer, JH; Wu, T | 1 |
| Olson, MS; Zhou, W | 1 |
| Antosiewicz, J; Bertoli, E; Fiorini, R; Kantar, A; Tanfani, F; Tartaglini, E; Wozniak, M | 1 |
| Coburn, JP; Eggleton, P; Ghebrehiwet, B; Sastry, KN; Tauber, AI; Zaner, KS | 1 |
| Javors, MA; Olson, MS; Zhou, W | 1 |
| Arai, Y; Kamata, K; Kasuya, Y | 1 |
| Bolognese, B; Griswold, DE; Jacobs, R; Marshall, LA; Roshak, A; Sung, CM; Webb, EF; Winkler, JD | 1 |
| Connelly, PA; Farrell, CA; Richard, S; Shaw, AS; Showell, HJ | 1 |
| Marshall, CJ; Saklatvala, J; Thompson, HL | 1 |
| Krämer, K; Markwitan, A; Pallauf, J | 1 |
| Frojmovic, MM; Rochon, YP | 1 |
| Blom, M; Koenderman, L; Kok, PT; Lammers, JW; Raaijmakers, JA; van der Bruggen, T; Verhoeven, AJ | 1 |
| Bowen, JG; Meats, JE; Steele, L | 1 |
| Becker, I; Huber, W; Peskar, BM; Schenck, U; Schepp, W; Trautmann, M | 1 |
| Aprile, B; Buzzi, E; Leoncini, G | 1 |
| Ishibashi, T; Nakamura, M; Nishihira, J; Sakamoto, W; Takeichi, N | 1 |
| Gardner, CR; Laskin, DL; Laskin, JD | 1 |
| Pelech, SL; Samiei, M; Sanghera, JS | 1 |
| Aramaki, Y; Ichimori, Y; Masuya, H; Nishinaka, Y; Sugawara, T; Yoshida, H | 1 |
| Heimburger, M; Lerner, R; Palmblad, J | 1 |
| Johnston, FL; Kanwar, S; Kubes, P; Reinhardt, PH; Woodman, RC | 1 |
| Chen, JJ; Liew, CC | 1 |
| Boll, RM; Gustafson-Svärd, C; Kald, B; Tagesson, C | 1 |
| Ahmed, A; Plevin, R; Shoaibi, MA; Smith, SK | 1 |
| Chyczewski, L; Debek, W; Gruca, A; Gruca, P | 1 |
| Samuelsson, J | 1 |
| Fallani, A; Manning, R; Ruggieri, S | 1 |
| Denizot, Y; Dulery, C; Dupuis, F; Fixe, P; Praloran, V | 1 |
| Akamatsu, H; Kanoh, T; Kurisaka, M; Niwa, Y; Ozaki, Y | 1 |
| Buravkova, L; Erne, P; Köhler, E; Mirzapoyazova, T; Resink, T; Tkachuk, V | 1 |
| Dohi, T; Kitayama, S; Morita, K; Okamoto, H; Shibata, K | 1 |
| Clough, J; Cypcar, D; Kaplan, M; Lemanske, RF; Nagata, M; Sedgwick, J; Sorkness, R | 1 |
| Ciccarelli, A; Cirillo, R; de Crescenzo, G; de Paulis, A; Marone, G; Patella, V | 1 |
| Clark, S; Dunlop, ME; Larkins, RG; Mahadevan, P; Muggli, E | 1 |
| Obata, Y; Oda, M; Yamamoto, N; Yokota, K | 1 |
| Knol, EF; Lie, WJ; Mul, FP; Roos, D; Verhoeven, AJ | 1 |
| Parent, JL; Rola-Pleszczynski, M; Stankova, J; Thivierge, M | 1 |
| Ali, H; Haribabu, B; Richardson, RM; Snyderman, R | 1 |
| Walker, BA | 1 |
| Ambruso, DR; Cusack, N; Malech, HL; Peterson, VM; Rosenthal, J; Thurman, GW | 1 |
| Anderson, R; Feldman, C; Theron, AJ | 1 |
| Bjerve, KS; Bleivik, B; White, LR | 1 |
| Ali, H; Fisher, I; Haribabu, B; Richardson, RM; Snyderman, R | 1 |
| Patarroyo, M; Salcedo, R; Wasserman, K | 1 |
| Jackson, CG; Stewart, A; Wakelam, MJ | 1 |
| Mutoh, H; Shimizu, T | 1 |
| Kruse-Elliott, KT | 1 |
| Anderson, J; Chen, E; Shamsuddin, M; Smith, LJ | 1 |
| Dent, G; Leff, AR; Magnussen, H; Muñoz, NM; Rabe, KF; Rühlmann, E; Zhu, X | 1 |
| Meyer, T; Oancea, E; Quest, AF; Teruel, MN | 1 |
| Cao, Y; McIntyre, TM; Prescott, SM; Stafforini, DM; Zimmerman, GA | 1 |
| al-Hage, M; Ezeamuzie, CI; Nwankwoala, RN | 1 |
| Gajate, C; Lazo, PA; Martín-Martín, B; Mollinedo, F | 1 |
| Baumann, FG; Colvin, SB; Galloway, AC; Grossi, EA; Jacobs, CE; Minneci, PC; Schwartz, DS; Schwartz, JD; Shamamian, P; Steiner, F | 1 |
| Kula, P; Kurmanowska, Z; Nowak, D; Stolarek, R | 1 |
| Burke-Gaffney, A; Hellewell, PG | 1 |
| Chaban, K; Darien, B; Grossman, JE; Kamke, C; Kruse-Elliott, KT; Tomasko, S | 1 |
| Le Blanc, K; Lindahl, T; Rosendahl, K; Samuelsson, J | 1 |
| Alexander, JS; Coe, L; Itoh, M; Okayama, N; Oshima, T | 1 |
| Bartemes, KR; Gleich, GJ; Kita, H; McKinney, S | 1 |
| Blom, M; Roos, D; Tool, AT; Verhoeven, AJ | 1 |
| Bos, JL; Coffer, PJ; Koenderman, L; M'Rabet, L; Wolthuis, RM; Zwartkruis, F | 1 |
| Barnett, CC; Fullerton, DA; Meldrum, DR; Moore, EE; Partrick, DA; Silliman, CC | 1 |
| Brown, GE; Burke, PA; Forse, RA; Xu, J; Yaffe, MB | 1 |
| Arnautova, IP; Gamaleĭ, IA; Kirpichnikova, KM; Kliubin, IV | 1 |
| Cunningham, FM; Lees, P; Marr, KA | 1 |
| Barros, FS; Dutra, PM; Lopes, AH; Meyer-Fernandes, JR; Rodrigues, CO; Souto-Padrón, T | 1 |
| Akkerman, JW; Bos, JL; de Bruijn, KM; Franke, B; Negrier, C; Nieuwenhuis, HK; van Triest, M; van Willigen, G | 1 |
| Chen, JS; Chen, LW; Shen, AY; Wu, SN | 1 |
| Hashimoto, M; Ito, M; Nakajima, T; Tchoua, U; Tojo, H | 1 |
| Bochner, BS; Brummet, ME; Davenpeck, KL; Hudson, SA; Mayer, RJ | 1 |
| Dutra, PM; Lopes, AH; Pereira, AF; Rosa , MS; Vieira, RB | 1 |
| Blodgett, JL; Bloodworth, RC; McManus, LM; Pinckard, RN; Prihoda, TJ | 1 |
| Al-Ghoul, WM; Choudhry, MA; Fazal, N; Sayeed, MM | 1 |
| Hanson, AJ; Quinn, MT; Siemsen, DW; Swain, SD | 1 |
| Haynes, J; Obiako, B | 1 |
| Clay, K; Dinauer, M; Hiran, T; Johnson, C; Travers, J | 1 |
| Ishii, S; Izumi, T; Ohshima, N; Shimizu, T | 1 |
| Bianchi, L; Cellai, C; Della Malva, N; Laurenzana, A; Paoletti, F; Vannucchi, AM | 1 |
| Chow, KC; Wang, LS; Wu, YC | 1 |
| Bulger, E; Cuschieri, J; Garcia, I; Gourlay, D; Jelacic, S; Maier, RV | 1 |
| Abal, AT; Abul, HT; Haines, DD; Mahmoud, FF; Wise, JA | 1 |
| Chow, KC; Fang, HY; Lin, JP; Lin, TS; Wang, LS; Wu, YC | 1 |
| Kamei, C; Ogawa, M; Sugimoto, Y; Tai, N | 1 |
| Homburg, CH; Knol, EF; Kuijpers, TW; Lie, WJ; Mul, FP; Roos, D; Tool, AT | 1 |
| Kitazawa, S; Tanigawara, Y; Tokumura, A; Tsutsumi, T; Yamaguchi, M | 1 |
| Bankers-Fulbright, JL; Bartemes, KR; Kephart, GM; Kita, H; O'Grady, SM | 1 |
| Creer, MH; Kell, PJ; McHowat, J; Meyer, MC | 1 |
| Gao, XP; Lin, P; Malik, AB; Welch, EJ; Ye, RD | 1 |
| Collino, M; Dianzani, C; Fantozzi, R; Gallicchio, M; Menicagli, R; Samaritani, S; Signore, G | 1 |
| Fraser, JF; Fung, YL; Tung, JP; Wood, P | 1 |
| Crystal, GJ; Eom, W; Hu, G; Kim, SJ; Saad, MM | 1 |
| DaSilva, SC; Konger, RL; Kozman, AA; Martel, KC; Rezania, S; Sahu, RP; Travers, JB; Warren, SJ; Yao, Y | 1 |
| Wang, HL; Wang, LC; Wei, JW | 1 |
| Enk, AH; Hadaschik, EN; Hartl, D; Hoffmann, JHO; Schaekel, K | 1 |
4 review(s) available for tetradecanoylphorbol acetate and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
| Article | Year |
|---|---|
Platelet protein phosphorylation.
Topics: Actin Cytoskeleton; Blood Platelets; Blood Proteins; Calcium; Carrier Proteins; Cyclic AMP; Cytoplasmic Granules; Cytoskeleton; Diglycerides; Gelsolin; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lysophospholipids; Microfilament Proteins; Microtubules; Molecular Weight; Myosins; Phosphatidic Acids; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane A2 | 1985 |
Impaired activation of phospholipase D in polycythaemia vera-implications for the pathogenesis of the disease?
Topics: Enzyme Activation; Humans; Inositol 1,4,5-Trisphosphate; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidative Stress; Phospholipase D; Platelet Activating Factor; Polycythemia Vera; Tetradecanoylphorbol Acetate | 1995 |
The role of basophils in allergic disease.
Topics: Asthma; Basophils; Bronchoalveolar Lavage Fluid; Calcium; Cell Degranulation; Chymases; Complement C5a; Cytokines; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histamine Release; Humans; Hypersensitivity; Interleukin-3; Interleukin-5; N-Formylmethionine Leucyl-Phenylalanine; Nasal Lavage Fluid; Phorbol Esters; Platelet Activating Factor; Prostaglandin D2; Receptors, IgE; Serine Endopeptidases; Skin; Tetradecanoylphorbol Acetate; Thapsigargin; Tryptases | 1996 |
Structure and regulation of platelet activating factor receptor gene.
Topics: Amino Acid Sequence; Animals; Base Sequence; CHO Cells; Cloning, Molecular; Cricetinae; Cricetulus; Endometrium; Endotoxins; Estrogens; Female; Gene Expression Regulation; Genes; Genes, Reporter; Humans; Macrophages; Mice; Molecular Sequence Data; Platelet Activating Factor; Platelet Membrane Glycoproteins; Promoter Regions, Genetic; Protein Conformation; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Tretinoin; Triiodothyronine | 1997 |
1 trial(s) available for tetradecanoylphorbol acetate and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
| Article | Year |
|---|---|
Effect of gallopamil on neutrophil function: experimental and clinical studies.
Topics: Angioplasty, Balloon, Coronary; Coronary Disease; Gallopamil; Humans; In Vitro Techniques; Neutrophils; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
286 other study(ies) available for tetradecanoylphorbol acetate and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine
| Article | Year |
|---|---|
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
C-reactive protein inhibits intracellular calcium mobilization and superoxide production by guinea pig alveolar macrophages.
Topics: Animals; C-Reactive Protein; Calcium; Dose-Response Relationship, Drug; Female; Guinea Pigs; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Superoxide anion release induced by platelet-activating factor is increased in human alveolar macrophages from smokers.
Topics: Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Lung Diseases; Macrophages, Alveolar; Male; Middle Aged; Platelet Activating Factor; Smoking; Superoxides; Tetradecanoylphorbol Acetate | 1992 |
Superoxide production by human eosinophils can be inhibited in an agonist-selective manner.
Topics: Alkaloids; Androstadienes; Carbazoles; Eosinophils; Humans; Immunoglobulin G; Indole Alkaloids; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Wortmannin; Zymosan | 1992 |
A novel pathway for the activation of phospholipase D by P2z purinergic receptors in BAC1.2F5 macrophages.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line, Transformed; Choline; Cytosol; Digitonin; Diglycerides; Enzyme Activation; Inositol Phosphates; Ionomycin; Kinetics; Macrophages; Mice; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phospholipase D; Phosphoric Diester Hydrolases; Platelet Activating Factor; Receptors, Purinergic; Simian virus 40; Tetradecanoylphorbol Acetate | 1992 |
A new, one-step assay on whole cell suspensions for peroxidase secretion by human neutrophils and eosinophils.
Topics: Calcimycin; Cell Separation; Eosinophil Peroxidase; Eosinophils; Humans; Indicators and Reagents; L-Lactate Dehydrogenase; Neutrophils; Oligopeptides; Peroxidase; Peroxidases; Platelet Activating Factor; Reference Values; Spectrophotometry; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Basal and phorbol-ester-stimulated turnover of phosphatidylcholine in HeLa cells involve different pathways.
Topics: Cell Membrane; Diacylglycerol Kinase; Diglycerides; HeLa Cells; Humans; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Phosphotransferases; Platelet Activating Factor; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases | 1992 |
Involvement of tyrosine kinase and protein kinase C in platelet-activating-factor-induced c-fos gene expression in A-431 cells.
Topics: Alkaloids; Blotting, Northern; Cinnamates; Colforsin; Cycloheximide; Gene Expression; Genes, fos; Genistein; Humans; Isoflavones; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; RNA; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Thrombin promotes actin polymerization in U937 human monocyte-macrophage cells. Analysis of the signalling mechanisms mediating actin polymerization.
Topics: Actins; Alkaloids; Calcium; Cations, Divalent; Cell Line; Chemotaxis, Leukocyte; GTP-Binding Proteins; Humans; Indoles; Ionomycin; Macrophages; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Polymers; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Virulence Factors, Bordetella | 1992 |
Effect of ozone on platelet-activating factor production in phorbol-differentiated HL60 cells, a human bronchial epithelial cell line (BEAS S6), and primary human bronchial epithelial cells.
Topics: Bronchi; Calcimycin; Cell Differentiation; Cells, Cultured; Chromatography, Thin Layer; Epithelial Cells; Epithelium; Humans; Ozone; Platelet Activating Factor; Radioimmunoassay; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Ligand dependent release of activated neutrophil collagenase--a role for surface bound IgG in the degradation of articular collagens.
Topics: Arthritis, Rheumatoid; Cartilage, Articular; Collagenases; Humans; Immunoglobulin G; Ligands; Matrix Metalloproteinase 8; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Antigen, B-Cell; Synovial Fluid; Tetradecanoylphorbol Acetate; Zymosan | 1992 |
Evidence for the presence and location of annexins in human platelets.
Topics: Annexin A1; Annexin A2; Annexin A4; Annexin A5; Annexins; Antibodies; Blood Platelets; Blotting, Western; Cross Reactions; Cytoplasmic Granules; Edetic Acid; Egtazic Acid; Enzyme-Linked Immunosorbent Assay; Humans; Ionomycin; Kinetics; Platelet Activating Factor; Platelet Activation; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1992 |
The involvement of products of the phospholipase pathway in the acute release of tissue-type plasminogen activator from perfused rat hindlegs.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; L-Lactate Dehydrogenase; Male; Pertussis Toxin; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tissue Plasminogen Activator; Type C Phospholipases; Virulence Factors, Bordetella; von Willebrand Factor | 1992 |
Cell response kinetics: the phenomenon of supercooperativity in aggregation of human platelets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Calcimycin; Epinephrine; Humans; Kinetics; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Tetradecanoylphorbol Acetate; Thimerosal | 1992 |
HLA-DR genes are silenced in human trophoblasts and stimulation of signal transduction pathways does not circumvent interferon-gamma unresponsiveness.
Topics: Calcimycin; Cholera Toxin; Colforsin; Female; Genes, MHC Class II; HLA-DR Antigens; Humans; Interferon-gamma; Ionomycin; Placenta; Platelet Activating Factor; Pregnancy; Receptors, Immunologic; Receptors, Interferon; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Trophoblasts; Virulence Factors, Bordetella | 1992 |
Platelet-activating factor modulates endotoxin-induced macrophage procoagulant activity by a protein kinase C-dependent mechanism.
Topics: Animals; Blood Coagulation Factors; Calcium; Endotoxins; Female; In Vitro Techniques; Indomethacin; Macrophages; Mice; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
Platelet-activating factor-stimulated protein tyrosine phosphorylation and eicosanoid synthesis in rat Kupffer cells. Evidence for calcium-dependent and protein kinase C-dependent and -independent pathways.
Topics: Animals; Blotting, Western; Calcimycin; Calcium; Down-Regulation; Egtazic Acid; Eicosanoids; Electrophoresis, Polyacrylamide Gel; Gallic Acid; Kupffer Cells; Phosphorylation; Platelet Activating Factor; Precipitin Tests; Protein Kinase C; Radioimmunoassay; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine | 1992 |
Selective inhibition of protein kinase C. Effect on platelet-activating-factor-induced platelet functional responses.
Topics: Animals; Blood Platelets; Calcium; Enzyme Activation; Indoles; Kinetics; Maleimides; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Kinase C; Rabbits; Serotonin; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1992 |
Phosphorylation of the inhibitory guanine-nucleotide-binding protein as a possible mechanism of inhibition by protein kinase C of agonist-induced Ca2+ mobilization in human platelet.
Topics: Alkaloids; Amino Acid Sequence; Arginine Vasopressin; Blood Platelets; Blotting, Western; Calcium; Enzyme Activation; GTP-Binding Proteins; Humans; Molecular Sequence Data; Phosphorylation; Platelet Activating Factor; Precipitin Tests; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1992 |
Quantification of contributions of phospholipid precursors to diradylglycerols in stimulated mononuclear phagocytes.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Diglycerides; Ionomycin; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phospholipids; Platelet Activating Factor; Radiometry; Tetradecanoylphorbol Acetate | 1992 |
Release of reactive oxygen species by guinea pig tracheal epithelial cells in vitro.
Topics: Analysis of Variance; Animals; Cell Membrane; Cells, Cultured; Epithelium; Guinea Pigs; Hydrogen Peroxide; Indomethacin; Male; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Trachea | 1992 |
The effect of serine and thiol protease inhibitors on the chemiluminescence of human neutrophils in investigations in vitro.
Topics: Calcimycin; Cysteine Proteinase Inhibitors; Humans; In Vitro Techniques; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Serine Proteinase Inhibitors; Tetradecanoylphorbol Acetate; Tosylarginine Methyl Ester; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Tyrosine; Zymosan | 1992 |
Effects of okadaic acid on agonist-stimulated PGI2 production by rat liver cells (the C-9 cell line).
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Ethers, Cyclic; Kinetics; Liver; Okadaic Acid; Phosphoprotein Phosphatases; Platelet Activating Factor; Prostaglandins F; Radioimmunoassay; Rats; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Modulation of leukotriene B4 and platelet-activating factor binding to neutrophils.
Topics: Alkaloids; Calcium; Cell Membrane; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; Neutrophils; Platelet Activating Factor; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Platelet-activating factor synergizes with phorbol myristate acetate in activating phospholipase D in the human promonocytic cell line U937. Evidence for different mechanisms of activation.
Topics: Azepines; Cell Line; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Glycerophospholipids; Humans; Kinetics; Monocytes; Phosphatidic Acids; Phosphatidylinositols; Phospholipase D; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate; Triazoles; Type C Phospholipases | 1991 |
Tumor necrosis factor-alpha primes pulmonary hemodynamic response to N-formyl-L-methionyl-L-leucyl-L-phenylalanine.
Topics: Animals; Antioxidants; Drug Synergism; Guinea Pigs; Hemodynamics; Lung; N-Formylmethionine Leucyl-Phenylalanine; Organ Size; Peroxidase; Platelet Activating Factor; Pulmonary Circulation; Tetradecanoylphorbol Acetate; Thromboxane A2; Tumor Necrosis Factor-alpha; Vascular Resistance | 1991 |
Stimulation of platelet-activating factor synthesis in human endothelial cells by activation of the de novo pathway. Phorbol 12-myristate 13-acetate activates 1-alkyl-2-lyso-sn-glycero-3-phosphate:acetyl-CoA acetyltransferase and dithiothreitol-insensitiv
Topics: Acetates; Acetyltransferases; Arachidonic Acids; Cells, Cultured; Choline; Diacylglycerol Cholinephosphotransferase; Dithiothreitol; Endothelium, Vascular; Humans; Kinetics; Phosphotransferases; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Umbilical Veins | 1991 |
Differential effects of propranolol on responses to receptor-dependent and receptor-independent stimuli in human neutrophils.
Topics: Calcium; Humans; In Vitro Techniques; Ionomycin; Isomerism; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipase D; Platelet Activating Factor; Propranolol; Respiratory Burst; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Comparison of the role of protein kinase C in platelet functional responses induced by three different mechanisms, PAF, ionomycin and arachidonic acid.
Topics: Alkaloids; Animals; Arachidonic Acid; Calcium; Feedback; Ionomycin; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Membrane Glycoproteins; Protein Kinase C; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1991 |
Endothelin increases [Ca2+]i, protein phosphorylation, and O2-. production in human alveolar macrophages.
Topics: Adult; Bronchoalveolar Lavage Fluid; Calcium; Endothelins; Female; Humans; In Vitro Techniques; Macrophage Activation; Macrophages, Alveolar; Male; Middle Aged; Phosphorylation; Platelet Activating Factor; Proteins; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Neutrophil chemiluminescence and superoxide production in patients with rheumatoid arthritis: the effect of zymosan, phorbol myristate acetate and platelet-activating factor.
Topics: Arthritis, Rheumatoid; Humans; Luminescent Measurements; Neutrophils; Platelet Activating Factor; Superoxides; Synovial Fluid; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Platelet-activating factor may participate in signal transduction processes in rabbit leukocytes.
Topics: Animals; Arachidonic Acid; Azepines; Blood Platelets; Calcimycin; Chloroquine; Female; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Triazoles | 1991 |
Protein kinase C is not involved in the desensitization of platelet activating factor receptor in rabbit platelets.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Platelets; Cell Membrane; Guanosine Triphosphate; Inositol Phosphates; Isoquinolines; Kinetics; Neomycin; Piperazines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1991 |
Biological response of guinea pig peritoneal macrophages to platelet-activating factor.
Topics: Animals; Female; Guinea Pigs; Hydrogen Peroxide; Kinetics; Macrophages; Macrophages, Alveolar; Mice; Mice, Inbred ICR; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1991 |
Platelet-activating factor stimulates receptor-mediated formation of reactive oxygen intermediates in human monocytes.
Topics: Cells, Cultured; Humans; Luminescent Measurements; Monocytes; Oxygen; Platelet Activating Factor; Platelet Membrane Glycoproteins; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1991 |
IgA immune aggregates stimulate platelet-activating factor and superoxide anion production by human neutrophils. A comparison with IgG aggregates.
Topics: Cytochalasin B; Humans; Immunoglobulin A; Immunoglobulin Fab Fragments; Immunoglobulin G; In Vitro Techniques; Macromolecular Substances; Multiple Myeloma; Neutrophils; Platelet Activating Factor; Reference Values; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Characteristics of CR3-mediated aggregation in human eosinophils: effect of priming by platelet-activating factor.
Topics: Antigens, CD; CD18 Antigens; Cell Aggregation; Cell Separation; Complement C3b; Eosinophils; Flow Cytometry; Humans; Latex; Lymphocyte Activation; Macrophage-1 Antigen; Opsonin Proteins; Platelet Activating Factor; Receptors, Leukocyte-Adhesion; Reference Values; Tetradecanoylphorbol Acetate | 1991 |
Effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on substance P-induced histamine release from rat peritoneal mast cells.
Topics: Animals; Ascitic Fluid; Calcium; Cyclohexanones; Female; Histamine Release; In Vitro Techniques; Male; Mast Cells; Platelet Activating Factor; Pyrimidinones; Rats; Rats, Inbred Strains; Substance P; Tetradecanoylphorbol Acetate; Thiazoles | 1990 |
Protein kinase C and cyclic AMP modulate thrombin-induced platelet-activating factor synthesis in human endothelial cells.
Topics: Acetyltransferases; Arachidonic Acid; Arachidonic Acids; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Humans; Iloprost; Ionomycin; Kinetics; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Eosinophil activation on biologic surfaces. Production of O2- in response to physiologic soluble stimuli is differentially modulated by extracellular matrix components and endothelial cells.
Topics: Endothelium, Vascular; Eosinophils; Extracellular Matrix; Humans; In Vitro Techniques; Inflammation; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Substance P; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1991 |
Long time incubation of monocytic U 937 cells with LDL increases specific paf-acether binding and the cellular acetylhydrolase activity.
Topics: Acetylesterase; Azepines; Cell Line; Humans; Lipoproteins, LDL; Macrophages; Monocytes; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Triazoles | 1991 |
Phorbol ester stimulates PAF synthesis via the activation of protein kinase C in rat leukocytes.
Topics: Acetyltransferases; Alkaloids; Animals; Enzyme Activation; In Vitro Techniques; Kinetics; Leukocytes; Male; Microsomes; Platelet Activating Factor; Platelet Aggregation; Protein Kinase C; Rabbits; Rats; Rats, Inbred Strains; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Immunoregulatory functions of paf-acether. VI. Dual effect on human B cell proliferation.
Topics: B-Lymphocytes; Burkitt Lymphoma; Cell Line; Cells, Cultured; DNA Replication; Humans; Kinetics; Lymphocyte Activation; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thymidine; Tritium | 1991 |
Platelet activating factor-induced pulmonary accumulation of 111Indium-oxine labelled neutrophils in anesthetized guinea pigs.
Topics: Analysis of Variance; Anesthesia, General; Animals; Guinea Pigs; In Vitro Techniques; Indium Radioisotopes; Kinetics; Lung; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Organometallic Compounds; Oxyquinoline; Platelet Activating Factor; Radioisotope Dilution Technique; Tetradecanoylphorbol Acetate | 1991 |
Second messenger pathways in lymphocyte binding and penetration through graft vascular endothelium.
Topics: Animals; Bucladesine; Calcimycin; Cell Communication; Cells, Cultured; Cyclic AMP; Endothelium, Vascular; Lymphocytes; Platelet Activating Factor; Rats; Rats, Inbred Strains; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1991 |
Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes.
Topics: Binding Sites; Calcimycin; Diglycerides; Enzyme Activation; Humans; Kinetics; Leukotriene B4; Monocytes; Opsonin Proteins; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Metabolism of platelet-activating factor in human haematopoietic cell lines. Differences between myeloid and lymphoid cells.
Topics: Acetates; Acetyltransferases; B-Lymphocytes; Burkitt Lymphoma; Cell Differentiation; Cell Line; Cell Membrane; Humans; Kinetics; Lymphoma, Large B-Cell, Diffuse; Phospholipids; Platelet Activating Factor; Platelet Membrane Glycoproteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sulfuric Acid Esters; T-Lymphocytes; Temperature; Tetradecanoylphorbol Acetate | 1991 |
Superoxide responses to formyl-methionyl-leucyl-phenylalanine in primed neutrophils. Role of intracellular and extracellular calcium.
Topics: Calcium; Cytoplasm; Extracellular Space; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Ionomycin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Activation of protein kinase C inhibits hormonal stimulation of the GTPase activity of Gi in human platelets.
Topics: Adenosine Diphosphate Ribose; Alprostadil; Blood Platelets; Enzyme Activation; Epinephrine; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Pertussis Toxin; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin; Virulence Factors, Bordetella | 1991 |
Interferon-gamma enhances PAF-acether production by stimulated human polymorphonuclear leucocytes.
Topics: Antigen-Antibody Complex; Cells, Cultured; Humans; Interferon-gamma; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1991 |
Biosynthesis of paf-acether. XVII. Regulation by the CoA-independent transacylase in human neutrophils.
Topics: Acetates; Acetyltransferases; Acyltransferases; Choline; Homeostasis; Humans; In Vitro Techniques; Kinetics; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1991 |
Modulation of neurite outgrowth in neuroblastoma cells by protein kinase C and platelet-activating factor.
Topics: Animals; Cell Division; Humans; Mice; Neurites; Neuroblastoma; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1991 |
Platelet activating factor induces expression of early response genes c-fos and TIS-1 in human epidermoid carcinoma A-431 cells.
Topics: Cycloheximide; Gene Expression Regulation, Neoplastic; Genes, fos; Humans; Kinetics; Platelet Activating Factor; Pyridinium Compounds; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Priming of neutrophil oxidative responses by platelet-activating factor.
Topics: Adult; Cytochalasin B; Drug Synergism; Humans; In Vitro Techniques; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Neutrophil erythrotoxicity induced by phorbol myristate acetate: mechanisms involved in neutrophil activation.
Topics: Antigen-Antibody Complex; Calcimycin; Catalase; Cell Adhesion; Cell Survival; Chemotaxis; Dose-Response Relationship, Drug; Erythrocytes; Humans; Immunity, Cellular; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phagocytosis; Platelet Activating Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Time Factors | 1991 |
Respiratory syncytial virus infection of human mononuclear phagocytes stimulates synthesis of platelet-activating factor.
Topics: Acetyltransferases; Cell Line; Chromatography, High Pressure Liquid; Enzyme Activation; Humans; Phagocytes; Platelet Activating Factor; Respiratory Syncytial Viruses; Respirovirus Infections; Tetradecanoylphorbol Acetate; Virus Replication | 1991 |
Shape changes, exocytosis, and cytosolic free calcium changes in stimulated human eosinophils.
Topics: Alkaloids; Calcium; Complement C5a; Eosinophils; Exocytosis; Humans; Interleukin-8; N-Formylmethionine Leucyl-Phenylalanine; Peroxidases; Pertussis Toxin; Platelet Activating Factor; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1991 |
Chelation of cytoplasmic Ca2+ increases plasma membrane permeability in murine macrophages.
Topics: Adenosine Triphosphate; Aminoquinolines; Animals; Calcium; Cell Line; Cell Membrane Permeability; Chelating Agents; Cytoplasm; Down-Regulation; Egtazic Acid; Enzyme Activation; Kinetics; Macrophages; Membrane Potentials; Mice; Molecular Weight; Pentetic Acid; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Generation of platelet activating factor (PAF) by a human lung epithelial cell line.
Topics: Animals; Calcimycin; Cell Line; Chromatography, High Pressure Liquid; Epithelial Cells; Epithelium; Humans; Lung; Platelet Activating Factor; Platelet Aggregation; Rabbits; Serum Albumin, Bovine; Tetradecanoylphorbol Acetate | 1990 |
Enhancement of thrombin- and ionomycin-stimulated prostacyclin and platelet-activating factor production in cultured endothelial cells by a tumor-promoting phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Arachidonic Acids; Calcimycin; Cells, Cultured; Dinoprost; Dinoprostone; Endothelium, Vascular; Epoprostenol; Humans; Ionomycin; Isoquinolines; Phorbol Esters; Phospholipases A; Phospholipases A2; Piperazines; Platelet Activating Factor; Prostaglandin D2; Prostaglandins H; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Aequorin-detected calcium changes in stimulated thrombasthenic platelets. Aggregation-dependent calcium movement in response to ADP.
Topics: Adenosine Diphosphate; Aequorin; Blood Platelet Disorders; Blood Platelets; Calcimycin; Calcium; Collagen; Humans; In Vitro Techniques; Luminescent Proteins; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombasthenia; Thrombin | 1990 |
Mechanism of N-formyl-methionyl-leucyl-phenylalanine- and platelet-activating factor-induced arachidonic acid release in guinea pig alveolar macrophages: involvement of a GTP-binding protein and role of protein kinase A and protein kinase C.
Topics: Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Down-Regulation; GTP-Binding Proteins; Guinea Pigs; Isoquinolines; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Pulmonary Alveoli; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1990 |
Effects of platelet-activating factor on peripheral blood monocytes: induction and priming for TNF secretion.
Topics: Calcium; Concanavalin A; Cytotoxicity, Immunologic; Drug Interactions; Humans; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Monocytes; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1990 |
Thromboxane release by lymphokine-differentiated U937 human monocytic cells: response to platelet-activating factor (PAF) and chemotactic peptide (FMLP) but not to low affinity IGE-receptor (Fc epsilon RII/CD23) occupation.
Topics: Antibodies, Anti-Idiotypic; Antigens, Differentiation, B-Lymphocyte; Calcimycin; Drug Synergism; Humans; Immunoglobulin E; Interferon-gamma; Interleukin-4; Leukemia, Monocytic, Acute; Lymphokines; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Protein Binding; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate; Thromboxane B2; Tumor Cells, Cultured | 1990 |
Biosynthesis of paf-acether. Activators of protein kinase C stimulate cultured mast cell acetyltransferase without stimulating paf-acether synthesis.
Topics: Acetyltransferases; Alkaloids; Animals; beta-N-Acetylhexosaminidases; Bone Marrow Cells; Calcium; Chlorpromazine; Chromatography, Gas; Cytoplasmic Granules; Enzyme Activation; Immunoglobulin E; Mast Cells; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Leukotriene B4 induced hyperadhesiveness of endothelial cells for neutrophils.
Topics: Cell Adhesion; Endothelium, Vascular; Humans; In Vitro Techniques; Leukotriene B4; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Time Factors | 1990 |
Regulation of oxytocin secretion by the ovine corpus luteum: effect of activators of protein kinase C.
Topics: Animals; Bucladesine; Calcimycin; Corpus Luteum; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Female; In Vitro Techniques; Oxytocin; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Pyrimidinones; Sheep; Tetradecanoylphorbol Acetate; Thiazoles; Type C Phospholipases | 1990 |
GM-CSF: receptor structure and transmembrane signaling.
Topics: Cell Membrane; Colony-Stimulating Factors; Cross-Linking Reagents; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Platelet Activating Factor; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Sepharose; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Platelet activating factor stimulates cyclo-oxygenase activity in guinea pig eosinophils. Concerted biosynthesis of thromboxane A2 and E-series prostaglandins.
Topics: Animals; Azepines; Calcimycin; Calcium; Complement C5a; Cyclooxygenase Inhibitors; Enzyme Activation; Eosinophils; Flurbiprofen; Guinea Pigs; Imidazoles; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Triazines; Triazoles | 1990 |
Evidence for the calcium-dependent activation of phospholipase D in thrombin-stimulated human erythroleukaemia cells.
Topics: Adenosine Diphosphate; Calcimycin; Calcium; Cell Line; Enzyme Activation; Epinephrine; Glycerophospholipids; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylinositols; Phospholipase D; Phospholipases; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Tumor Cells, Cultured | 1990 |
Translocation-independent activation of protein kinase C by platelet-activating factor, thrombin and prostacyclin. Lack of correlation with polyphosphoinositide hydrolysis in rabbit platelets.
Topics: Animals; Blood Platelets; Enzyme Activation; Epoprostenol; Hydrolysis; In Vitro Techniques; Phosphatidylinositols; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
IFN-gamma potentiates the accumulation of diacylglycerol in murine macrophages.
Topics: Animals; Calcium; Cells, Cultured; Diglycerides; Drug Synergism; Glycerides; In Vitro Techniques; Inositol Phosphates; Interferon-gamma; Ionomycin; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phosphatidylcholines; Phosphatidylinositols; Platelet Activating Factor; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1990 |
Calcium ionophore potentiates chemotactic peptide and platelet activating factor in stimulating thromboxane B2 and leukotriene B4 biosynthesis in human neutrophils.
Topics: Calcimycin; Drug Synergism; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Radioimmunoassay; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1990 |
PAF-acether transfer activity in HL-60 cells is induced during differentiation.
Topics: Bucladesine; Cell Differentiation; Cell Line; Chromatography, Gel; Cytosol; Dimethyl Sulfoxide; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Macrophages; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1990 |
Two distinct pathways of platelet-activating factor-induced hydrolysis of phosphoinositides in primary cultures of rat Kupffer cells.
Topics: Animals; Calcium; Cells, Cultured; Cholera Toxin; Chromatography, High Pressure Liquid; Egtazic Acid; Gallic Acid; In Vitro Techniques; Inositol Phosphates; Kupffer Cells; Pertussis Toxin; Phosphatidylinositols; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate; Time Factors; Virulence Factors, Bordetella | 1990 |
Regulation of platelet-activating factor receptor and PAF receptor-mediated arachidonic acid release by protein kinase C activation in rat Kupffer cells.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cells, Cultured; Dimethyl Sulfoxide; Down-Regulation; Enzyme Activation; Kinetics; Kupffer Cells; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1990 |
Changes of fluorescence anisotropy in plasma membrane of human polymorphonuclear leukocytes during the respiratory burst phenomenon.
Topics: Adult; Cell Membrane; Diphenylhexatriene; Fluorescent Dyes; Humans; Kinetics; Luminescence; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Spectrometry, Fluorescence; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Platelet-activating factor- and leukotriene B4-induced release of lactoferrin from blood neutrophils of atopic and nonatopic individuals.
Topics: Adult; Cytochalasin B; Enzyme-Linked Immunosorbent Assay; Female; Humans; In Vitro Techniques; Lactoferrin; Lactones; Leukotriene B4; Male; Neutrophils; Plant Extracts; Platelet Activating Factor; Rhinitis; Tetradecanoylphorbol Acetate | 1990 |
Selective inhibition of human neutrophil functional responsiveness by erbstatin, an inhibitor of tyrosine protein kinase.
Topics: Calcimycin; Chemotactic Factors; Humans; Hydroquinones; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine | 1990 |
Priming effect of fibronectin on respiratory burst of human neutrophils induced by formyl peptides and platelet-activating factor.
Topics: Dose-Response Relationship, Drug; Enzyme Activation; Fibronectins; Free Radicals; Humans; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Platelet Activating Factor; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
Effects of the protein kinase inhibitors, staurosporine and K-252a, on PGI2 production by rat liver cells (the C-9 cell line).
Topics: 6-Ketoprostaglandin F1 alpha; Alkaloids; Animals; Calcimycin; Carbazoles; Cell Line; Drug Synergism; Epoprostenol; Indole Alkaloids; Liver; Platelet Activating Factor; Protein Kinase C; Radioimmunoassay; Rats; Staurosporine; Tetradecanoylphorbol Acetate | 1990 |
Generation of oxygen free radicals from blood eosinophils from asthma patients after stimulation with PAF or phorbol ester.
Topics: Adult; Aged; Asthma; Eosinophils; Female; Free Radicals; Humans; Luminescent Measurements; Male; Middle Aged; Oxygen; Oxygen Consumption; Platelet Activating Factor; Pulmonary Eosinophilia; Rhinitis; Tetradecanoylphorbol Acetate | 1990 |
Assessment of vascular permeability increase in the mouse by dye leakage during paw edema.
Topics: Animals; Bradykinin; Capillary Permeability; Coloring Agents; Dose-Response Relationship, Drug; Edema; Foot; Histamine; Male; Mice; Mice, Inbred ICR; Phospholipid Ethers; Platelet Activating Factor; Pyrilamine; Tetradecanoylphorbol Acetate | 1990 |
Agonist and antagonist of oxygen free radical.
Topics: Cells, Cultured; Endotoxins; Humans; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Pyridinium Compounds; Temperature; Tetradecanoylphorbol Acetate; Verapamil | 1990 |
Mechanism of calcium ionophore A23187-induced priming of bone marrow-derived macrophages for tumor cell killing: relationship to priming by interferon.
Topics: Animals; Bone Marrow Cells; Calcimycin; Cytotoxicity, Immunologic; Diglycerides; Dose-Response Relationship, Drug; Interferons; Lipopolysaccharides; Macrophages; Male; Mice; Neoplasms, Experimental; Phorbols; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1985 |
[Blocking with phorbol ester, a protein kinase C activator, of receptor-dependent platelet calcium channels].
Topics: Blood Platelets; Calcium; Enzyme Activation; Fluorescent Dyes; Humans; In Vitro Techniques; Ion Channels; Kinetics; Phorbols; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate; Thrombin | 1985 |
Evidence for the receptor-operated calcium channels in human platelet plasma membrane.
Topics: Alprostadil; Aminoquinolines; Barium; Biological Transport; Blood Platelets; Calcium; Cell Membrane; Humans; In Vitro Techniques; Ion Channels; Platelet Activating Factor; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1987 |
Arachidonic acid release in rabbit neutrophils.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1989 |
Phorbol diester enhances calcium ionophore A23187-induced [3H]acetate incorporation into platelet-activating factor in murine macrophages: predominant incorporation into 1-O-acyl-2-acetyl-sn-glycero-3-phosphocholine.
Topics: Animals; Calcimycin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Macrophages; Mice; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Augmented production of platelet-activating factor in human polymorphonuclear leukocytes by ketone bodies.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Calcimycin; Dimethyl Sulfoxide; Humans; Hydroxybutyrates; In Vitro Techniques; Kinetics; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1989 |
Thrombin causes increased monocytic-cell adhesion to endothelial cells through a protein kinase C-dependent pathway.
Topics: Animals; Aspirin; Calcimycin; Cattle; Cell Adhesion; Endothelium, Vascular; Heparin; Humans; In Vitro Techniques; Monocytes; Platelet Activating Factor; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Modulation of arterial endothelial permeability: studies on an in vitro model.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Albumins; Animals; Aorta, Thoracic; Arteries; Bradykinin; Calcimycin; Catalase; Endothelium, Vascular; Histamine; In Vitro Techniques; Muscle, Smooth, Vascular; Permeability; Platelet Activating Factor; Superoxide Dismutase; Swine; Tetradecanoylphorbol Acetate | 1989 |
Acetyltransferase activity and production of platelet-activating factor by human neutrophils activated with various stimuli.
Topics: Acetyltransferases; Calcimycin; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Desensitization of platelet-activating factor-stimulated protein phosphorylation in platelets.
Topics: Animals; Blood Platelets; In Vitro Techniques; Molecular Weight; Phospholipid Ethers; Phosphoproteins; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridinium Compounds; Quinolines; Quinolinium Compounds; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1989 |
Bidirectional effects of protein kinase C activators. Studies with human neutrophils and platelet-activating factor.
Topics: Calcium; Dimethyl Sulfoxide; Exocytosis; Humans; Neutrophils; Peroxidase; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate; Transcobalamins | 1989 |
Selective inactivation by endogenous protein kinase C of human platelet high-affinity GTPase coupled with PAF receptors.
Topics: Adenylyl Cyclases; Blood Platelets; Colforsin; Enzyme Activation; Epinephrine; GTP Phosphohydrolases; Humans; In Vitro Techniques; Phosphoric Monoester Hydrolases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate | 1989 |
Phorbol 12-myristate 13-acetate inhibits binding of leukotriene B4 and platelet-activating factor and the responses they induce in neutrophils: site of action.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arachidonic Acids; Calcium; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Neutrophils; Piperazines; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Leukotriene B4; SRS-A; Tetradecanoylphorbol Acetate | 1989 |
Phospholipase A2-mediated release of arachidonic acid in stimulated guinea pig alveolar macrophages: interaction with lipid mediators and cyclic AMP.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acids; Bronchoalveolar Lavage Fluid; Calcimycin; Cyclic AMP; Dinoprostone; Guinea Pigs; Lipid Metabolism; Lipids; Macrophages; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Pulmonary Alveoli; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1989 |
Protein kinase C blockers and neutrophil receptors for leukotriene B4.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Leukotriene B4; Neutrophils; Piperazines; Platelet Activating Factor; Protein Kinase C; Receptors, Immunologic; Receptors, Leukotriene B4; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Thermodynamics | 1989 |
The inhibitory effects of cannabinoids, the active constituents of Cannabis sativa L. on human and rabbit platelet aggregation.
Topics: Animals; Cannabinoids; Epinephrine; Humans; In Vitro Techniques; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Tetradecanoylphorbol Acetate | 1989 |
Pharmacological demonstration of inflammatory mediators using experimental inflammatory models: rat pleurisy induced by carrageenin and phorbol myristate acetate.
Topics: Animals; Capillary Permeability; Carrageenan; Disease Models, Animal; Epoprostenol; Guinea Pigs; Inflammation; Kinins; Platelet Activating Factor; Pleurisy; Prostaglandins; Rabbits; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
The regulation of platelet-activating factor production in endothelial cells. The role of calcium and protein kinase C.
Topics: Adenine Nucleotides; Animals; Bacterial Toxins; Bradykinin; Calcium; Cations, Divalent; Cattle; Cytoplasm; Endothelium; Hemolysin Proteins; In Vitro Techniques; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
Effect of platelet-activating factor on monocyte activation and production of tumor necrosis factor.
Topics: Cell Line; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Macrophage Activation; Macrophages; Monocytes; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 1989 |
Involvement of protein kinase C in platelet-activating factor-stimulated diacylglycerol accumulation in murine peritoneal macrophages.
Topics: Animals; Diglycerides; Ethers; Glycerides; Hydrolysis; Ionomycin; Ionophores; Macrophages; Mice; Mice, Inbred C57BL; Peritoneal Cavity; Phosphatidylcholines; Phosphatidylinositols; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Biosynthesis of paf-acether. X. Phorbol myristate acetate-induced paf-acether biosynthesis and acetyltransferase activation in human neutrophils.
Topics: Acetyltransferases; Chromatography, Gas; Diglycerides; Enzyme Activation; Humans; Neutrophils; Opsonin Proteins; Phagocytosis; Platelet Activating Factor; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
Differential activation by fMet-Leu-Phe and phorbol ester of a plasma membrane phosphatidylcholine-specific phospholipase D in human neutrophil.
Topics: Cell Membrane; Cytochalasin B; Enzyme Activation; Humans; Hydrolysis; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Phospholipase D; Phospholipases; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1989 |
Staurosporine potentiates platelet activating factor stimulated phospholipase C activity in rabbit platelets but does not block desensitization by platelet activating factor.
Topics: Alkaloids; Animals; Blood Platelets; Drug Synergism; In Vitro Techniques; Inositol; Inositol Phosphates; Kinetics; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Rabbits; Staurosporine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1989 |
Platelet-activating factor increases inositol phosphate production and cytosolic free Ca2+ concentrations in cultured rat Kupffer cells.
Topics: Animals; Calcium; Cells, Cultured; Cytosol; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kupffer Cells; Male; Platelet Activating Factor; Protein Kinase C; Quinolines; Rats; Rats, Inbred Strains; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1989 |
Histamine formed in stimulated human platelets is cytoplasmic.
Topics: Blood Platelets; Cytoplasm; Female; Histamine; Humans; Male; Phosphatidylethanolamines; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Saponins; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Protein kinase C activity appears to be required for the synthesis of platelet-activating factor and leukotriene B4 by human neutrophils.
Topics: Amines; Enzyme Activation; Humans; Leukotriene B4; Neutrophils; Palmitoylcarnitine; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1987 |
Biosynthesis of platelet-activating factor in human polymorphonuclear leukocytes. Involvement of the cholinephosphotransferase pathway in response to the phorbol esters.
Topics: Acetyltransferases; Calcimycin; Choline; Diacylglycerol Cholinephosphotransferase; Diglycerides; Dithiothreitol; Dose-Response Relationship, Drug; Glyceryl Ethers; Humans; Neutrophils; Phorbol Esters; Phosphotransferases; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1988 |
Attenuation of platelet activating factor (PAF)-induced stimulation of rabbit platelet GTPase by phorbol ester, dibutyryl cAMP, and desensitization: concomitant effects on PAF receptor binding characteristics.
Topics: Animals; Blood Platelets; Bucladesine; GTP Phosphohydrolases; Phosphoric Monoester Hydrolases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate; Thrombin | 1988 |
Platelet-activating factor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate stimulates the production of reactive oxygen intermediates in macrophages.
Topics: Calcimycin; Cells, Cultured; Diglycerides; Hydrolysis; Inositol Phosphates; Macrophages; Oxygen; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Platelet Activating Factor; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
The priming of neutrophils by lipopolysaccharide for production of intracellular platelet-activating factor. Potential role in mediation of enhanced superoxide secretion.
Topics: Adjuvants, Immunologic; Body Fluids; Calcium; Cytosol; Dose-Response Relationship, Immunologic; Humans; Intracellular Fluid; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Mechanism involved in the mobilization of neutrophil calcium by 5-hydroxyeicosatetraenoate.
Topics: Calcium; Cholera Toxin; Cytosol; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Leukotriene; Receptors, Prostaglandin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1988 |
Platelet activating factor and leukotriene B4 induce hyperpolarization of human endothelial cells but depolarization of neutrophils.
Topics: Calcimycin; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Leukotriene B4; Membrane Potentials; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1988 |
Activation of monocytes by interferon-gamma has no effect on the level or affinity of the nicotinamide adenine dinucleotide-phosphate oxidase and on agonist-dependent superoxide formation.
Topics: Calcium; Cells, Cultured; Cytochrome b Group; Humans; Hydrogen Peroxide; Interferon-gamma; Kinetics; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Oxygen Consumption; Platelet Activating Factor; Protein Kinase C; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Cytosolic calcium, oxygen consumption and the intracellular pH of stimulated neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cell Separation; Concanavalin A; Cytoplasm; Digitonin; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Protons; Sodium; Tetradecanoylphorbol Acetate | 1988 |
Influence of platelet activating factor and a nonmetabolizable analogue on superoxide production by bone marrow derived macrophages.
Topics: Bone Marrow Cells; Humans; Luminescent Measurements; Lysophosphatidylcholines; Macrophages; Platelet Activating Factor; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Leukotriene C4 production from human eosinophils in vitro. Role of eosinophil chemotactic factors on eosinophil activation.
Topics: Adult; Calcimycin; Cells, Cultured; Chemotactic Factors; Chemotactic Factors, Eosinophil; Enzyme Activation; Eosinophils; Female; Humans; Leukotriene B4; Male; Phosphatidylserines; Platelet Activating Factor; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1988 |
Function and stimulus-specific effects of phorbol 12-myristate 13-acetate on human polymorphonuclear neutrophils: autoregulatory role for protein kinase C in signal transduction.
Topics: Exocytosis; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pepstatins; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
An endogenous source of the superoxide anion in the central nervous system.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Concanavalin A; Kinetics; Microscopy, Electron; Neuroglia; Platelet Activating Factor; Potassium Chloride; Rats; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Platelet-activating factor stimulates prolactin release from dispersed rat anterior pituitary cells in vitro.
Topics: Animals; Bromocriptine; Cells, Cultured; Dose-Response Relationship, Drug; Growth Hormone; Kinetics; Luteinizing Hormone; Male; Phosphatidylcholines; Pituitary Gland, Anterior; Platelet Activating Factor; Prolactin; Rats; Tetradecanoylphorbol Acetate; Thyrotropin | 1989 |
The influence of activating hormones on human platelet membrane Ca2+-ATPase activity.
Topics: Adenosine Diphosphate; Alprostadil; Blood Platelets; Calcimycin; Calcium-Transporting ATPases; Cell Membrane; Colforsin; Ethers; Humans; Ionomycin; Kinetics; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1986 |
Tumour-promoting phorbol esters inhibit agonist-induced phosphatidate formation and Ca2+ flux in human platelets.
Topics: Blood Platelets; Calcium; Carcinogens; Enzyme Activation; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylinositols; Platelet Activating Factor; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1985 |
Platelet-activating factor mediated effects on human neutrophil function are inhibited by pertussis toxin.
Topics: Bacterial Toxins; Cell Aggregation; Chemotaxis, Leukocyte; Cytochalasin B; GTP-Binding Proteins; Humans; Muramidase; Neutrophils; Pertussis Toxin; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1985 |
Unique inhibitory profile of platelet activating factor induced calcium mobilization, polyphosphoinositide turnover and granule enzyme secretion in rabbit neutrophils towards pertussis toxin and phorbol ester.
Topics: Aminoquinolines; Animals; Bacterial Toxins; Calcium; Cytoplasmic Granules; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phorbols; Phosphatidic Acids; Phosphatidylinositol Phosphates; Phosphatidylinositols; Platelet Activating Factor; Rabbits; Tetradecanoylphorbol Acetate; Type C Phospholipases; Virulence Factors, Bordetella | 1985 |
Modulation of neutrophil oxidative responses to soluble stimuli by platelet-activating factor.
Topics: Adult; Diglycerides; Fatty Acids; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Oxygen Consumption; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
Oxygen radical production by neutrophils from patients with bacterial infection and rheumatoid arthritis. Measurement of hydrogen peroxide may most accurately represent enhancement of oxygen radical production during infection.
Topics: Arthritis, Rheumatoid; Bacterial Infections; C-Reactive Protein; Calcimycin; Cytochalasin B; Free Radicals; Humans; Hydrogen Peroxide; Leukocyte Count; Neutrophils; Oxygen; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1986 |
A comparative study on the effects of inhibitors of the lipoxygenase pathway on neutrophil function. Inhibitory effects on neutrophil function may not be attributed to inhibition of the lipoxygenase pathway.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Benzoquinones; Calcimycin; Chemotaxis, Leukocyte; Epoprostenol; Humans; Hydroxides; Hydroxyl Radical; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinones; Tetradecanoylphorbol Acetate; Umbelliferones | 1986 |
Biochemical events associated with the stimulation of rabbit neutrophils by platelet-activating factor.
Topics: Actins; Animals; Calcium; Carrier Proteins; Chlortetracycline; Cholera Toxin; Cytoskeleton; Egtazic Acid; Exocytosis; GTP-Binding Proteins; Hydrogen-Ion Concentration; In Vitro Techniques; Neutrophils; Pertussis Toxin; Phosphatidylinositols; Platelet Activating Factor; Rabbits; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Arachidonate metabolites, platelet-activating factor, and the mobilization of protein kinase C in human polymorphonuclear neutrophils.
Topics: Arachidonic Acid; Arachidonic Acids; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Membrane; Cell-Free System; Cytosol; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Neutrophils; Platelet Activating Factor; Protamine Kinase; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Solubility; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1987 |
G-protein dissociation, GTP-GDP exchange and GTPase activity in control and PMA treated neutrophils stimulated by fMet-Leu-Phe.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Membrane; Cell-Free System; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphoric Monoester Hydrolases; Platelet Activating Factor; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Signalling for increased cytoskeletal actin in neutrophils.
Topics: Actins; Animals; Calcimycin; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Osmolar Concentration; Pertussis Toxin; Platelet Activating Factor; Rabbits; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
Influence of lysophospholipids and PAF on the oxidative burst of PMNL.
Topics: Acetophenones; Animals; Complement C5; Complement C5a; Female; Guinea Pigs; In Vitro Techniques; Luminescent Measurements; Lysophosphatidylcholines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Platelet-activating factor effects on bovine pulmonary artery endothelial cells.
Topics: Adenylyl Cyclases; Animals; Cattle; Dose-Response Relationship, Drug; Endothelium; Epoprostenol; Isoproterenol; Phosphatidylinositols; Platelet Activating Factor; Pulmonary Artery; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1987 |
The onset of the respiratory burst in human neutrophils. Real-time studies of H2O2 formation reveal a rapid agonist-induced transduction process.
Topics: Ethers; Humans; Hydrogen Peroxide; Ionomycin; Kinetics; Leukotriene B4; Luminescent Measurements; Mathematics; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1987 |
A defect of platelet release reaction in a patient with SLE: impaired platelet aggregation induced by phorbol ester with a normal phosphorylation of 40K protein.
Topics: Adenosine Diphosphate; Adult; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Blood Proteins; Calcimycin; Collagen; Diglycerides; Epinephrine; Female; Humans; Lupus Erythematosus, Systemic; Phorbols; Phosphorylation; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombin | 1986 |
A novel mechanism of diglyceride formation. 12-O-tetradecanoylphorbol-13-acetate stimulates the cyclic breakdown and resynthesis of phosphatidylcholine.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Choline; Diglycerides; Dogs; Glycerides; Kidney; Palmitic Acid; Palmitic Acids; Phorbols; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1986 |
Inhibition by antioxidants of agonist evoked cytosolic Ca++ increase, ATP secretion and aggregation of aspirinated human platelets.
Topics: Adenosine Triphosphate; Antioxidants; Aspirin; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Calcium; Egtazic Acid; Ferrous Compounds; Humans; Masoprocol; Organometallic Compounds; Platelet Activating Factor; Platelet Aggregation; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1986 |
Effect of phorbol 12-myristate 13-acetate (PMA) on agonist-induced arachidonate release and 5-hydroxytryptamine secretion in human platelets. Dependence of effects on agonist type and time of incubation with PMA.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Collagen; Epinephrine; Humans; In Vitro Techniques; Kinetics; Male; Platelet Activating Factor; Prostaglandin Endoperoxides, Synthetic; Serotonin; Tetradecanoylphorbol Acetate; Thrombin | 1987 |
Phorbol ester-induced formation of clastogenic factor from human monocytes.
Topics: Arachidonic Acid; Arachidonic Acids; Chromosome Aberrations; Humans; Leukotrienes; Lipid Metabolism; Lipid Peroxides; Monocytes; Mutagens; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1987 |
Chemoattractant-induced activation of c-fos gene expression in human monocytes.
Topics: beta 2-Microglobulin; Cycloheximide; Dactinomycin; Gene Expression Regulation; GTP-Binding Proteins; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Pertussis Toxin; Platelet Activating Factor; Protein Biosynthesis; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transcriptional Activation; Virulence Factors, Bordetella | 1987 |
Synthesis and release of platelet-activating factor by stimulated human mononuclear phagocytes.
Topics: Calcimycin; Cell Adhesion; Cell Differentiation; Humans; Macrophage Activation; Monocytes; Opsonin Proteins; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1988 |
Adherence of human basophils to cultured umbilical vein endothelial cells.
Topics: Basophils; Calcimycin; Cations, Divalent; Cell Adhesion; Cell Line; Complement C5; Complement C5a; Cycloheximide; Dactinomycin; Endothelium, Vascular; Glucocorticoids; Humans; Interleukin-1; Kinetics; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Temperature; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Umbilical Veins | 1988 |
Release of prostaglandin E2 and thromboxane B2 by mixed isolated human lung cells.
Topics: Bradykinin; Calcimycin; Cells, Cultured; Dinoprostone; Humans; Immunoenzyme Techniques; Lung; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Prostaglandins E; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1988 |
Stereospecific bioactions of 5-hydroxyeicosatetraenoate.
Topics: Calcium; Diglycerides; Exocytosis; Glucuronidase; Humans; Hydroxyeicosatetraenoic Acids; Muramidase; Neutrophils; Platelet Activating Factor; Stereoisomerism; Tetradecanoylphorbol Acetate | 1988 |
Enhancement of phorbol ester-induced protein kinase activity in human neutrophils by platelet-activating factor.
Topics: Calcium; Cytochalasin B; Enzyme Activation; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1988 |
Platelet-activating factor-induced homologous and heterologous desensitization in cultured vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Benzofurans; Calcium; Cells, Cultured; Cytosol; Diglycerides; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Male; Muscle, Smooth, Vascular; Platelet Activating Factor; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Vasopressins | 1988 |
Modulation of platelet-activating-factor-induced calcium influx and intracellular calcium release in platelets by phorbol esters.
Topics: Blood Platelets; Calcium; Cations, Divalent; Diglycerides; Epoprostenol; Humans; Intracellular Fluid; Platelet Activating Factor; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thrombin | 1987 |
Detection of platelet-activating factor in exudates of rats with phorbol myristate acetate-induced pleurisy.
Topics: Animals; Carrageenan; Chromatography, High Pressure Liquid; Leukocytes; Male; Platelet Activating Factor; Platelet Aggregation; Pleurisy; Rabbits; Rats; Rats, Inbred Strains; Reference Values; Tetradecanoylphorbol Acetate | 1987 |
[Cytoplasm free calcium ions as a second messenger].
Topics: Aequorin; Aminoquinolines; Blood Platelets; Calcium; Humans; Ions; Platelet Activating Factor; Platelet Aggregation; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2 | 1987 |
A step sensitive to pertussis toxin and phorbol ester in human neutrophils regulates chemotaxis and capping but not phagocytosis.
Topics: Chemotaxis, Leukocyte; Concanavalin A; Fluorescein-5-isothiocyanate; Fluoresceins; Fluorescent Dyes; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phagocytosis; Phorbols; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1986 |
Characterization of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (AGEPC)-induced protein phosphorylation in rabbit platelets: inhibitory effects of AGEPC analogs.
Topics: Animals; Blood Platelets; Blood Proteins; Molecular Weight; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Rabbits; Tetradecanoylphorbol Acetate | 1986 |
Differential effects of 12-O-tetradecanoylphorbol 13-acetate on platelet responses to various agonists in the presence and absence of extracellular Ca2+.
Topics: Adenosine Triphosphate; Aminoquinolines; Blood Platelets; Calcium; Cytosol; Humans; Platelet Activating Factor; Platelet Aggregation; Prostaglandin Endoperoxides, Synthetic; Tetradecanoylphorbol Acetate; Thrombin; Vasopressins | 1986 |
Suppression of phorbol myristate acetate-induced pleurisy by CV-3988, an antagonist of platelet-activating factor.
Topics: Animals; Male; Phospholipid Ethers; Platelet Activating Factor; Pleurisy; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thiazoles | 1986 |
Stimulation of hepatic glycogenolysis by 12-O-tetradecanoyl-phorbol-13-acetate (TPA) via cyclooxygenase products.
Topics: Acetophenones; Animals; Female; Glucose; Indomethacin; Liver Glycogen; Perfusion; Phorbols; Phospholipases A; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1985 |
Various authentic chemoattractants mediating leukocyte adherence inhibition.
Topics: Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Adhesion; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5; Complement C5a, des-Arginine; Humans; Leukocyte Adherence Inhibition Test; Leukocytes; Leukotriene B4; Liver Neoplasms; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; SRS-A; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
Neutrophil-degranulating action of 5,12-dihydroxy-6,8,10,14-eicosatetraenoic acid and 1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine. Comparison with other degranulating agents.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cattle; Chemotactic Factors; Cytochalasin B; Cytoplasmic Granules; Humans; In Vitro Techniques; Leukotriene B4; Lysophosphatidylcholines; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Rabbits; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1981 |
Evidence for 5, 12-dihydroxy-6,8,10,14-eicosatetraenoate as a mediator of human neutrophil aggregation.
Topics: Arachidonic Acids; Calcimycin; Cell Aggregation; Chemotaxis, Leukocyte; Complement C5; Complement C5a; Humans; Kinetics; Leukotriene B4; Lysophosphatidylcholines; N-Formylmethionine; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1981 |
Diacylglycerols enhance human neutrophil degranulation responses: relevancy to a multiple mediator hypothesis of cell function.
Topics: Animals; Calcimycin; Cytoplasmic Granules; Diglycerides; Glycerides; Humans; Kinetics; Muramidase; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Rabbits; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
Release of platelet-activating factor from HL-60 human leukemic cells following macrophage-like differentiation.
Topics: Cell Line; Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Leukocytes; Lysophosphatidylcholines; Macrophages; Platelet Activating Factor; Receptors, Complement; Tetradecanoylphorbol Acetate | 1982 |
Formation of second messenger diradylglycerol in murine peritoneal macrophages is altered after in vivo (n-3) polyunsaturated fatty acid supplementation.
Topics: Animals; Cells, Cultured; Diet; Diglycerides; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Food, Fortified; Linear Models; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Platelet Activating Factor; Random Allocation; Second Messenger Systems; Specific Pathogen-Free Organisms; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Human endothelial cells are targets for platelet-activating factor (PAF). Activation of alpha and beta protein kinase C isozymes in endothelial cells stimulated by PAF.
Topics: Actins; Amino Acid Sequence; Antibodies; Cell Membrane; Cells, Cultured; Chromatography, Ion Exchange; Cytoskeletal Proteins; Cytosol; Diglycerides; Diterpenes; Endothelium, Vascular; Enzyme Activation; Ginkgolides; Humans; Isoenzymes; Kinetics; Lactones; Molecular Sequence Data; Naphthalenes; Peptides; Phospholipid Ethers; Platelet Activating Factor; Polycyclic Compounds; Protein Kinase C; Protein Kinase Inhibitors; Tetradecanoylphorbol Acetate; Thiazoles; Vinculin | 1994 |
CD11b/CD18 (Mac-1) is required for degranulation of human eosinophils induced by human recombinant granulocyte-macrophage colony-stimulating factor and platelet-activating factor.
Topics: Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Cell Degranulation; Eosinophils; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Integrins; Macrophage-1 Antigen; Platelet Activating Factor; Recombinant Proteins; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Cyclosporin A blocks induction of tumor necrosis factor-alpha in human B lymphocytes.
Topics: B-Lymphocytes; Cell Line; Cyclosporine; Drug Interactions; Gene Expression; Humans; Interleukin-6; Platelet Activating Factor; RNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1994 |
Endothelial cell associated platelet-activating factor (PAF), a costimulatory intermediate in TNF-alpha-induced H2O2 release by adherent neutrophil leukocytes.
Topics: Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Humans; Hydrogen Peroxide; Interleukin-8; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Tetradecanoylphorbol Acetate; Thrombin; Tumor Necrosis Factor-alpha; Umbilical Veins | 1995 |
In vitro effects of oxidized low density lipoprotein on CD11b/CD18 and L-selectin presentation on neutrophils and monocytes with relevance for the in vivo situation.
Topics: 1-Butanol; Adult; Animals; Butanols; CD18 Antigens; Cell Adhesion Molecules; Cells, Cultured; Cricetinae; Female; Flow Cytometry; Fluorescence Polarization; Humans; L-Selectin; Lipoproteins, LDL; Macrophage-1 Antigen; Male; Mesocricetus; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentoxifylline; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1995 |
Rat, mouse and human neutrophils stimulated by a variety of activating agents produce much less nitrite than rodent macrophages.
Topics: Adult; Amino Acid Oxidoreductases; Animals; Cells, Cultured; Female; Humans; Interferon-gamma; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred Strains; Neutrophil Activation; Neutrophils; Nitric Oxide Synthase; Nitrites; Platelet Activating Factor; Rats; Rats, Inbred F344; Species Specificity; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1995 |
CD66 family members are associated with tyrosine kinase activity in human neutrophils.
Topics: Antigens, CD; Antigens, Differentiation; Cell Adhesion Molecules; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate | 1995 |
Cell type specificity and protein kinase C dependency on the stimulation of prostaglandin E2 and prostaglandin F2 alpha production by oxytocin and platelet-activating factor in bovine endometrial cells.
Topics: Animals; Cattle; Cells, Cultured; Dinoprost; Dinoprostone; Endometrium; Female; Oxytocin; Platelet Activating Factor; Prostaglandins; Protein Kinase C; Stimulation, Chemical; Tachyphylaxis; Tetradecanoylphorbol Acetate; Time Factors | 1995 |
Differential induction of stress proteins and functional effects of heat shock in human phagocytes.
Topics: Cadmium; Cadmium Compounds; Erythrocytes; Gene Expression Regulation; Hot Temperature; HSP70 Heat-Shock Proteins; Humans; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phagocytosis; Platelet Activating Factor; Respiratory Burst; Staphylococcus aureus; Sulfates; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1995 |
Acute pro-inflammatory actions of endothelin-1 in the guinea-pig lung: involvement of ETA and ETB receptors.
Topics: Animals; Azepines; Blood Pressure; Bosentan; Bronchopulmonary Sequestration; Capillary Permeability; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelins; Guinea Pigs; In Vitro Techniques; Indoles; Injections, Intravenous; Lung; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutropenia; Neutrophils; Peptide Fragments; Plasma Volume; Platelet Activating Factor; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Implication of protein kinase C alpha in PAF-stimulated phospholipase D activation in Chinese hamster ovary (CHO) cells expressing PAF receptor.
Topics: Animals; Cell Membrane; CHO Cells; Cricetinae; Cytosol; Enzyme Activation; Guinea Pigs; Immunoblotting; Isoenzymes; Kinetics; Palmitic Acid; Palmitic Acids; Phospholipase D; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Processing, Post-Translational; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Tetradecanoylphorbol Acetate; Transfection | 1995 |
Release of platelet activation factor from activated neutrophils. Transglutaminase-dependent enhancement of transbilayer movement across the plasma membrane.
Topics: Cell Membrane; Cystamine; Erythrocyte Membrane; Humans; In Vitro Techniques; Ionomycin; Kinetics; Lipid Bilayers; Membrane Lipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Sarcosine; Serum Albumin; Tetradecanoylphorbol Acetate; Time Factors; Transglutaminases | 1993 |
A platelet-activating factor antagonist, RP 55778, inhibits cytokine-dependent induction of human immunodeficiency virus expression in chronically infected promonocytic cells.
Topics: Cell Line; Chloramphenicol O-Acetyltransferase; Cytokines; Fluorescent Antibody Technique; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Reverse Transcriptase; HIV-1; Humans; Interleukin-6; Kinetics; Monocytes; Platelet Activating Factor; Pyridines; Recombinant Proteins; RNA Processing, Post-Transcriptional; RNA-Directed DNA Polymerase; RNA, Messenger; RNA, Viral; Tetradecanoylphorbol Acetate; Thiazoles; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 1993 |
Tyrosine-kinase activity in rabbit platelets stimulated with platelet-activating factor. The effect of inhibiting tyrosine kinase with genistein on platelet-signal-molecule elevation and functional responses.
Topics: Animals; Blood Platelets; Cells, Cultured; Genistein; Inositol 1,4,5-Trisphosphate; Ionomycin; Isoflavones; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Rabbits; Signal Transduction; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane A2; Type C Phospholipases; Tyrosine | 1993 |
5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration.
Topics: Arachidonic Acid; Arachidonic Acids; Cell Movement; Chemotaxis, Leukocyte; Eosinophils; Glucuronidase; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1995 |
Superoxide generation by guinea-pig peritoneal macrophages is inhibited by rolipram, staurosporine and mepacrine in an agonist-dependent manner.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Alkaloids; Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Guinea Pigs; Macrophages, Peritoneal; Male; N-Formylmethionine Leucyl-Phenylalanine; Phospholipases A; Phospholipases A2; Phosphoric Diester Hydrolases; Platelet Activating Factor; Protein Kinase C; Pyrrolidinones; Quinacrine; Respiratory Burst; Rolipram; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1994 |
Leukotriene-deficient mice generated by targeted disruption of the 5-lipoxygenase gene.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Bone Marrow Cells; Carrageenan; Dinoprostone; Female; Inflammation; Leukotriene C4; Leukotrienes; Macrophages; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Mutant Strains; Phagocytosis; Phenotype; Platelet Activating Factor; Spleen; Tetradecanoylphorbol Acetate | 1995 |
Mechanisms for lipoxin A4 induced neutrophil dependent cytotoxicity for human endothelial cells.
Topics: Azepines; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Triazoles; Umbilical Veins; Virulence Factors, Bordetella | 1995 |
Chemoattractants induce rapid release of the interleukin 1 type II decoy receptor in human polymorphonuclear cells.
Topics: Amino Acid Sequence; Calcimycin; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5a; Humans; In Vitro Techniques; Interleukin-1; Interleukin-8; Leukotriene B4; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oligopeptides; Platelet Activating Factor; Receptors, Interleukin-1; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1995 |
Activation of the transcription factor NF-kappa B in human tracheobronchial epithelial cells by inflammatory stimuli.
Topics: Bronchi; Cell Line, Transformed; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Epithelium; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrogen Peroxide; In Vitro Techniques; Interleukin-1; Lipopolysaccharides; NF-kappa B; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Trachea; Transcriptional Activation; Tumor Necrosis Factor-alpha; Up-Regulation | 1995 |
Platelet-activating factor (PAF) positively auto-regulates the expression of human PAF receptor transcript 1 (leukocyte-type) through NF-kappa B.
Topics: Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; DNA Primers; Gene Expression Regulation, Neoplastic; Humans; Leukocytes; Molecular Sequence Data; NF-kappa B; Open Reading Frames; Platelet Activating Factor; Platelet Membrane Glycoproteins; Promoter Regions, Genetic; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation | 1994 |
Regulation by protein kinase C of platelet-activating factor- and thapsigargin-induced calcium entry in rabbit neutrophils.
Topics: Alkaloids; Animals; Calcium; Calcium Chloride; Calcium-Transporting ATPases; Cytosol; Electrophysiology; Enzyme Activation; Inositol 1,4,5-Trisphosphate; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Spectrometry, Fluorescence; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1994 |
Effects of ZCR-2060 on allergic airway inflammation and cell activation in guinea-pigs.
Topics: Animals; Benzoates; Bronchoalveolar Lavage Fluid; Chemotaxis, Leukocyte; Eosinophils; Guinea Pigs; Inflammation; Leukotriene B4; Macrophages, Alveolar; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Piperidines; Platelet Activating Factor; Respiratory Hypersensitivity; Superoxides; Tetradecanoylphorbol Acetate | 1994 |
Stimulus-specific defect in platelet aggregation in polycythemia vera.
Topics: Adenosine Diphosphate; Aged; Aged, 80 and over; Blood Platelets; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Luminescent Measurements; Middle Aged; Multiple Myeloma; Platelet Activating Factor; Platelet Aggregation; Polycythemia Vera; Tetradecanoylphorbol Acetate | 1994 |
Cytokine regulation by platelet-activating factor in a human B cell line.
Topics: B-Lymphocytes; Blotting, Northern; Enzyme-Linked Immunosorbent Assay; Humans; Platelet Activating Factor; Protein Biosynthesis; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Modulatory role of protein kinase C on the signal transduction pathway utilized by platelet-activating factor in eosinophil activation.
Topics: Alkaloids; Animals; Azepines; Calcium; Cell Membrane; Cytosol; Eosinophil Peroxidase; Eosinophils; Guinea Pigs; Male; Peritoneal Lavage; Peroxidases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate; Triazoles | 1994 |
Priming of the oxidative burst in human neutrophils by physiological agonists or cytochalasin B results from the recruitment of previously non-responsive cells.
Topics: Cells, Cultured; Cytochalasin B; Cytokines; Fluorides; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Determinants of neutrophil HOCl generation: ligand-dependent responses and the role of surface adhesion.
Topics: Cell Adhesion; Cell Membrane; Humans; Hydrogen Peroxide; Hypochlorous Acid; Immunoglobulin G; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Peroxidase; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1994 |
Inhibitor of phospholipase A2 blocks eicosanoid and platelet activating factor biosynthesis and has topical anti-inflammatory activity.
Topics: Administration, Topical; Anti-Inflammatory Agents; Arachidonic Acid; Dermatitis; Eicosanoids; Humans; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Tretinoin | 1994 |
Wortmannin inhibits mitogen-activated protein kinase activation induced by platelet-activating factor in guinea pig neutrophils.
Topics: Androstadienes; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Egtazic Acid; Enzyme Activation; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Platelet Activating Factor; Tetradecanoylphorbol Acetate; Time Factors; Wortmannin | 1994 |
Platelet-activating factor induces airway mucin release via activation of protein kinase C: evidence for translocation of protein kinase C to membranes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cats; Cell Fractionation; Cell Membrane; Cells, Cultured; Centrifugation, Density Gradient; Enzyme Activation; Epithelium; Isoenzymes; Isoquinolines; Kinetics; Molecular Weight; Mucins; Piperazines; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Trachea | 1994 |
A mechanism for phorbol ester-mediated regulation of the PAF receptor in human neutrophils.
Topics: Calcimycin; Calcium; Cytochalasin B; Down-Regulation; Egtazic Acid; Humans; In Vitro Techniques; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1994 |
A sensitive detection of neutrophil activation by fluorescence quenching of membrane inserted singlet oxygen probe.
Topics: Benzofurans; Biphenyl Compounds; Cell Membrane; Cyclohexane Monoterpenes; Hydroxyl Radical; Monoterpenes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Onium Compounds; Oxygen; Photochemistry; Platelet Activating Factor; Singlet Oxygen; Spectrometry, Fluorescence; Terpenes; Tetradecanoylphorbol Acetate | 1994 |
Characterization of the human neutrophil C1q receptor and functional effects of free ligand on activated neutrophils.
Topics: Antibodies; Blotting, Western; Carrier Proteins; Cell Differentiation; Cell Membrane; Complement C1q; Humans; Hyaluronan Receptors; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; Macrophage-1 Antigen; Membrane Glycoproteins; Mitochondrial Proteins; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Receptors, Complement; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 1994 |
Impaired surface expression of PAF receptors on human neutrophils is dependent upon cell activation.
Topics: Calcimycin; Calcium; Cell Aggregation; Cell Membrane; Dose-Response Relationship, Drug; Down-Regulation; Egtazic Acid; Humans; In Vitro Techniques; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1994 |
Mechanism of the contractile response to platelet-activating factor (PAF) of the rat stomach fundus. II. PAF-induced phosphatidylinositol turnover and desensitization.
Topics: Animals; Carbachol; Gastric Fundus; Hydrolysis; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Phosphatidic Acids; Phosphatidylinositols; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
Effects of scalaradial, a type II phospholipase A2 inhibitor, on human neutrophil arachidonic acid mobilization and lipid mediator formation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Homosteroids; Humans; Leukotrienes; Male; Mice; Mice, Inbred BALB C; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Sesterterpenes; Terpenes; Tetradecanoylphorbol Acetate | 1994 |
C5a as a model for chemotactic factor-stimulated tyrosine phosphorylation in the human neutrophil.
Topics: Benzoquinones; Cell Line; Chemotactic Factors; Complement C5a; Humans; In Vitro Techniques; Interleukin-8; Lactams, Macrocyclic; Leukotriene B4; Models, Biological; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Quinones; Receptor, Anaphylatoxin C5a; Receptors, Complement; Rifabutin; RNA, Messenger; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Characterization of two different forms of mitogen-activated protein kinase kinase induced in polymorphonuclear leukocytes following stimulation by N-formylmethionyl-leucyl-phenylalanine or granulocyte-macrophage colony-stimulating factor.
Topics: Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Gel; Chromatography, Ion Exchange; Complement C5a; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoblotting; Interleukin-8; Isoenzymes; Leukotriene B4; Mitogen-Activated Protein Kinase Kinases; Molecular Weight; Mutagenesis, Site-Directed; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peptide Mapping; Phosphopeptides; Phosphoprotein Phosphatases; Platelet Activating Factor; Point Mutation; Protein Kinases; Protein Phosphatase 2; Recombinant Proteins; Tetradecanoylphorbol Acetate | 1994 |
Studies on the metabolism of metallothionein and alkaline phosphatase of adult rat primary hepatocyte cultures: role of fetal calf serum and agonists of the phosphoinositide cascade.
Topics: Alkaline Phosphatase; Angiotensin II; Animals; Arginine Vasopressin; Calcimycin; Cells, Cultured; Culture Media; Dexamethasone; Diglycerides; Liver; Metallothionein; Phosphatidylinositols; Platelet Activating Factor; Rats; Tetradecanoylphorbol Acetate; Zinc | 1993 |
Regulation of human neutrophil aggregation: comparable latent times, activator sensitivities, and exponential decay in aggregability for FMLP, platelet-activating factor, and leukotriene B4.
Topics: Adult; Cell Aggregation; Dose-Response Relationship, Drug; Humans; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Time Factors | 1993 |
Transient exposure of human eosinophils to the protein kinase C inhibitors CGP39-360, CGP41-251, and CGP44-800 leads to priming of the respiratory burst induced by opsonized particles.
Topics: Alkaloids; Calcium; Enzyme Inhibitors; Eosinophils; Humans; Opsonin Proteins; Organic Chemicals; Platelet Activating Factor; Protein Kinase C; Respiratory Burst; Staurosporine; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Identification of phospholipase D (PLD) activity in mouse peritoneal macrophages.
Topics: Animals; Calcimycin; Cells, Cultured; Chromatography, Thin Layer; Glycerophospholipids; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Phosphatidic Acids; Phospholipase D; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 1993 |
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate | 1993 |
S-D-lactoylglutathione accumulation in activated human platelets.
Topics: Blood Platelets; Calcimycin; Glutathione; Humans; In Vitro Techniques; Lactoylglutathione Lyase; Platelet Activating Factor; Platelet Activation; Tetradecanoylphorbol Acetate; Thiolester Hydrolases; Thrombin | 1993 |
A role for oxygen radicals in rat monocytic leukemia cell differentiation under stimulation with platelet-activating factor.
Topics: Animals; Catalase; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Kinetics; Leukemia, Experimental; Leukemia, Myeloid; Mannitol; Platelet Activating Factor; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Platelet-activating factor-induced calcium mobilization and oxidative metabolism in hepatic macrophages and endothelial cells.
Topics: Alprazolam; Animals; Calcium; Cells, Cultured; Endothelium; Female; Kinetics; Kupffer Cells; Liver; Oxygen Consumption; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate; Triazolam; Verapamil | 1993 |
Activation of myelin basic protein and S6 peptide kinases in phorbol ester- and PAF-treated sheep platelets.
Topics: Amino Acid Sequence; Animals; Blood Platelets; Calcium-Calmodulin-Dependent Protein Kinases; Cell Fractionation; Cytosol; Enzyme Activation; Glycogen Synthase Kinase 3; Molecular Sequence Data; Myelin Proteins; Phosphorylation; Platelet Activating Factor; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Sheep; Tetradecanoylphorbol Acetate | 1993 |
A new sensitive chemiluminescence probe, L-012, for measuring the production of superoxide anion by cells.
Topics: Complement C5a; Humans; Imidazoles; Indicators and Reagents; Interferon-gamma; Kinetics; Leukemia, Eosinophilic, Acute; Luminescent Measurements; Luminol; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Pyrazines; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Mechanism and regulation of neutrophil priming by platelet-activating factor.
Topics: Adult; Amiloride; Azepines; Calcium; Chelating Agents; Diacylglycerol Kinase; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Phosphotransferases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Pyrimidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate; Thiazoles; Triazoles; Type C Phospholipases; Virulence Factors, Bordetella | 1993 |
Lipoxin A4 induces hyperadhesiveness in human endothelial cells for neutrophils.
Topics: Calcium; Cell Adhesion; Endothelium, Vascular; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Interleukin-1; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Effects of human neutrophil elastase (HNE) on neutrophil function in vitro and in inflamed microvessels.
Topics: Animals; Cell Adhesion; Cephalosporins; Chemotaxis, Leukocyte; Endothelium, Vascular; Humans; Inflammation; Leukocyte Elastase; Male; Microcirculation; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Pyrrolidines; Rats; Rats, Wistar; Splanchnic Circulation; Superoxides; Tetradecanoylphorbol Acetate; Umbilical Veins; Venules | 1993 |
Phosphorylation of an acid-soluble nuclear protein in response to catecholamine in cultured rat cardiocytes.
Topics: Amino Acids; Animals; Cells, Cultured; Gene Expression Regulation; In Vitro Techniques; Myosins; Norepinephrine; Nuclear Proteins; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Rats; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Transcriptional Activation | 1993 |
Tumor necrosis factor-alpha potentiates phospholipase A2-stimulated release and metabolism of arachidonic acid in cultured intestinal epithelial cells (INT 407).
Topics: Arachidonic Acid; Calcimycin; Cell Line; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Epithelium; Humans; Intestinal Mucosa; Lipid Metabolism; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Type C Phospholipases | 1993 |
Oestradiol-17 beta modulates PAF-evoked phospholipase D activity but not inositide-lipid hydrolysis in human endometrial cell line, HEC-1B.
Topics: Carcinogens; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Endometrium; Epithelium; Estradiol; Female; Humans; Hydrolysis; Inositol 1,4,5-Trisphosphate; Phosphatidylinositols; Phospholipase D; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Type C Phospholipases; Up-Regulation | 1995 |
Luminol-chemiluminescence in free peritoneal cells in hemorrhagic shock in rats treated with PAF-receptor-antagonist BN 52021.
Topics: Analysis of Variance; Animals; Ascitic Fluid; Diterpenes; Female; Ginkgolides; Lactones; Luminescent Measurements; Luminol; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock, Hemorrhagic; Tetradecanoylphorbol Acetate | 1995 |
Lipid changes in HL-60 cells on differentiation into macrophages by treatment with a phorbol ester.
Topics: Arachidonic Acid; Carcinogens; Cell Differentiation; Cholesterol; Ethanolamines; HL-60 Cells; Humans; Lipid Metabolism; Macrophages; Phospholipids; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Triglycerides; Tumor Cells, Cultured | 1995 |
PAF and haematopoiesis. X. Macrophage colony-stimulating factor and granulocyte macrophage colony-stimulating factor enhance platelet-activating factor acetylhydrolase production by human blood-derived macrophages.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Cell Differentiation; Cells, Cultured; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Phospholipases A; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1996 |
Role of cytokines, tyrosine kinase, and protein kinase C on production of superoxide and induction of scavenging enzymes in human leukocytes.
Topics: Adult; Bleomycin; Calcimycin; Catalase; Cytokines; Enzyme Induction; Female; Glutathione Peroxidase; Humans; Interferon-gamma; Interleukin-1; Lymphocytes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Protein-Tyrosine Kinases; Respiratory Burst; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1996 |
Involvement of protein kinase C in hypoxia-induced desensitization of the beta-adrenergic system in human endothelial cells.
Topics: Adrenergic beta-Agonists; Cells, Cultured; Down-Regulation; Endothelium, Vascular; Histamine; Humans; Hypoxia; Isoproterenol; Phosphatidylinositols; Platelet Activating Factor; Protein Kinase C; Receptors, Adrenergic, beta; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Ca2+ entry induced by calcium influx factor and its regulation by protein kinase C in rabbit neutrophils.
Topics: Adrenal Glands; Alkaloids; Animals; Azepines; Calcium; Calcium Channel Blockers; Cattle; Chromaffin Granules; Enzyme Inhibitors; Imidazoles; Ion Transport; Neutrophils; Platelet Activating Factor; Protein Kinase C; Rabbits; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Triazoles | 1996 |
Rat eosinophils: isolation and characterization of superoxide production.
Topics: Animals; Calcimycin; Cell Separation; Cytochalasin B; Eosinophils; Humans; In Vitro Techniques; Kinetics; Male; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Rats; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Cyclosporin H is a potent and selective competitive antagonist of human basophil activation by N-formyl-methionyl-leucyl-phenylalanine.
Topics: Basophils; Binding, Competitive; Bryostatins; Chemokine CCL2; Chemokine CCL5; Complement C5a; Cyclosporine; Histamine Release; Humans; Interleukin-1; Interleukin-8; Kinetics; Lactones; Leukotriene C4; Macrolides; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Platelet Activating Factor; Protein Binding; Tetradecanoylphorbol Acetate | 1996 |
Production of hyaluronan by glomerular mesangial cells in response to fibronectin and platelet-derived growth factor.
Topics: Animals; Cyclooxygenase Inhibitors; Fibronectins; Glomerular Mesangium; Hyaluronic Acid; Male; Platelet Activating Factor; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1996 |
Inhibitory effects of the new anti-platelet agent KBT-3022 and its metabolite on rabbit neutrophil function in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Calcium; Cell Adhesion; Cilostazol; Complement C3-C5 Convertases; Complement C5a; Cyclooxygenase Inhibitors; Indomethacin; Leukotriene B4; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Platelet Aggregation Inhibitors; Pyrroles; Rabbits; Structure-Activity Relationship; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Thiazoles; Ticlopidine | 1996 |
Modulation of human platelet-activating factor receptor gene expression by protein kinase C activation.
Topics: Enzyme Activation; Gene Expression Regulation; Humans; Monocytes; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate | 1996 |
Cross-desensitization among receptors for platelet activating factor and peptide chemoattractants. Evidence for independent regulatory pathways.
Topics: Amino Acid Sequence; Calcium; Chemotactic Factors; Egtazic Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Interleukin-8; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Effects of adenosine on guinea pig pulmonary eosinophils.
Topics: Adenosine; Animals; Calcium; Eosinophils; Guinea Pigs; Ionomycin; Ionophores; Lung; Platelet Activating Factor; Receptors, Purinergic P1; Respiratory Hypersensitivity; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Neutrophils from patients after burn injury express a deficiency of the oxidase components p47-phox and p67-phox.
Topics: Adult; Burns; Cell-Free System; Cytochrome b Group; Cytosol; Disease Susceptibility; Female; Humans; Immunocompromised Host; Infections; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Oxygen; Phosphoproteins; Platelet Activating Factor; Respiratory Burst; Subcellular Fractions; Superoxides; Tetradecanoylphorbol Acetate | 1996 |
Membrane-stabilizing, anti-inflammatory interactions of macrolides with human neutrophils.
Topics: Adult; Anti-Asthmatic Agents; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Azithromycin; Calcimycin; Cell Membrane; Clarithromycin; Erythromycin; Humans; Ionophores; Luminescent Measurements; Lysophosphatidylcholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Respiratory Burst; Roxithromycin; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1996 |
Protein kinase C inhibitors and PAF stimulate phosphatidylserine synthesis in human leucocytes.
Topics: Antineoplastic Agents; Carbon Radioisotopes; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Male; Neutrophils; Phosphatidylserines; Phospholipid Ethers; Platelet Activating Factor; Protein Kinase C; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1996 |
Role of phospholipase Cbeta3 phosphorylation in the desensitization of cellular responses to platelet-activating factor.
Topics: Animals; Calcium; Cell Line; Cyclic AMP; Enzyme Inhibitors; Indoles; Inositol Phosphates; Isoenzymes; Kinetics; Maleimides; Phosphatidylinositols; Phospholipase C beta; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thionucleotides; Transfection; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Endogenous fibronectin of blood polymorphonuclear leukocytes: stimulus-induced secretion and proteolysis by cell surface-bound elastase.
Topics: Antibodies, Monoclonal; Cell Adhesion Molecules; Cell Membrane; Chemotactic Factors; Enzyme-Linked Immunosorbent Assay; Epitopes; Fibronectins; Flow Cytometry; Humans; Leukocyte Elastase; Leukotriene B4; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1997 |
The regulation by phosphorylation of 'priming' of phospholipase A2 activity in the neutrophil model system, differentiated HL60 cells.
Topics: Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Cell Differentiation; Cell Membrane; Cytochalasin B; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Lysophospholipids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein-Tyrosine Kinases; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1997 |
Pulmonary and neutrophil responses to priming effects of platelet-activating factor in pigs.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Blood Gas Analysis; Blood Pressure; Carcinogens; Cyclooxygenase Inhibitors; Indomethacin; Lipopolysaccharides; Neutrophils; Platelet Activating Factor; Random Allocation; Respiratory Physiological Phenomena; Respiratory System; Superoxides; Swine; Tetradecanoylphorbol Acetate; Time Factors; Vascular Resistance | 1997 |
Regulation of leukotriene and platelet-activating factor synthesis in human alveolar macrophages.
Topics: Acetyltransferases; Acyl-Carrier Protein S-Acetyltransferase; Arachidonic Acids; Asthma; Benzenesulfonates; Bronchoalveolar Lavage Fluid; Calcimycin; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; Humans; Ionophores; Leukotriene B4; Leukotrienes; Macrophages, Alveolar; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Urea | 1997 |
Protein kinase C inhibition enhances platelet-activating factor-induced eicosanoid production in human eosinophils.
Topics: Arachidonic Acid; Calcium; Catalase; Eicosanoids; Enzyme Inhibitors; Eosinophils; Female; Humans; Indoles; Leukotriene C4; Male; Maleimides; Naphthalenes; Phorbol 12,13-Dibutyrate; Platelet Activating Factor; Protein Kinase C; Respiratory Burst; Superoxides; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1998 |
Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells.
Topics: Animals; Arachidonic Acid; Cell Membrane; Cloning, Molecular; Cytosol; Diffusion; Diglycerides; Green Fluorescent Proteins; Isoenzymes; Luminescent Proteins; Nuclear Envelope; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, IgE; Recombinant Fusion Proteins; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Expression of plasma platelet-activating factor acetylhydrolase is transcriptionally regulated by mediators of inflammation.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Base Sequence; Cell Differentiation; Cell Line; Cloning, Molecular; Cytokines; Gene Expression Regulation; Genes, Reporter; Interferon-gamma; Lipopolysaccharides; Molecular Sequence Data; Phospholipases A; Platelet Activating Factor; Promoter Regions, Genetic; RNA, Messenger; Sequence Analysis, DNA; Tetradecanoylphorbol Acetate; Transcription, Genetic; Transfection | 1998 |
The effect of salmeterol on human eosinophils is both stimulus- and response-dependent.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; beta-N-Acetylhexosaminidases; Cell Adhesion; Eosinophil Peroxidase; Eosinophils; Fibronectins; Humans; Interleukin-5; Leukotriene B4; Peroxidases; Platelet Activating Factor; Propanolamines; Salmeterol Xinafoate; Superoxides; Tetradecanoylphorbol Acetate | 1997 |
Physiological activation of human neutrophils down-regulates CD53 cell surface antigen.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; Cells, Cultured; Down-Regulation; Humans; Ionomycin; Ionophores; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; RNA, Messenger; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Tetraspanin 25; Tumor Necrosis Factor-alpha | 1998 |
Cardiopulmonary bypass primes polymorphonuclear leukocytes.
Topics: Aged; Cardiopulmonary Bypass; Complement System Proteins; Cytokines; Female; Humans; Male; Middle Aged; Neutrophils; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate | 1998 |
Effect of various agonists on nitric oxide generation by human polymorphonuclear leukocytes.
Topics: Concanavalin A; Enzyme Inhibitors; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1998 |
A CD18/ICAM-1-dependent pathway mediates eosinophil adhesion to human bronchial epithelial cells.
Topics: Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Chemokine CCL11; Chemokine CCL4; Chemokine CCL5; Chemokines, CC; Complement C5a; Cytokines; Eosinophils; Epithelial Cells; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Kinetics; Leukotriene B4; Lung; Macrophage Inflammatory Proteins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Low molecular weight heparin alters porcine neutrophil responses to platelet-activating factor.
Topics: Animals; Chemotaxis; Dose-Response Relationship, Drug; Heparin; Molecular Weight; Neutrophils; Platelet Activating Factor; Superoxides; Swine; Tetradecanoylphorbol Acetate | 1998 |
Impaired platelet binding of fibrinogen due to a lower number of GPIIB/IIIA receptors in polycythemia vera.
Topics: Adult; Aged; Aged, 80 and over; Antigens, CD; Blood Platelets; Female; Fibrinogen; Flow Cytometry; Humans; Male; Middle Aged; Platelet Activating Factor; Platelet Activation; Platelet Glycoprotein GPIIb-IIIa Complex; Polycythemia Vera; Serotonin; Tetradecanoylphorbol Acetate | 1998 |
Intracellular mechanisms of hydrogen peroxide-mediated neutrophil adherence to cultured human endothelial cells.
Topics: Azepines; Calcimycin; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hydrogen Peroxide; In Vitro Techniques; Neutrophils; P-Selectin; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triazoles | 1999 |
Endogenous platelet-activating factor is critically involved in effector functions of eosinophils stimulated with IL-5 or IgG.
Topics: Eicosanoids; Eosinophils; Humans; Immunoglobulin G; Interleukin-5; Pertussis Toxin; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Pyridinium Compounds; Superoxides; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1999 |
Phospholipase D-derived phosphatidic acid is involved in the activation of the CD11b/CD18 integrin in human eosinophils.
Topics: Calcium; CD18 Antigens; Cell Adhesion; Cell Survival; Diglycerides; Enzyme Activation; Eosinophils; Ethanol; Fibronectins; Humans; Macrophage-1 Antigen; Phosphatidic Acids; Phospholipase D; Platelet Activating Factor; Propranolol; Protein Binding; Respiratory Burst; Tetradecanoylphorbol Acetate; Up-Regulation; Zymosan | 1999 |
Differential fMet-Leu-Phe- and platelet-activating factor-induced signaling toward Ral activation in primary human neutrophils.
Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; GTP Phosphohydrolases; GTP-Binding Proteins; GTPase-Activating Proteins; Humans; In Vitro Techniques; Kinetics; Mitogen-Activated Protein Kinase 1; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Proteins; ral GTP-Binding Proteins; rap GTP-Binding Proteins; ras GTPase-Activating Proteins; Signal Transduction; Tetradecanoylphorbol Acetate | 1999 |
Cardiopulmonary bypass renders patients at risk for multiple organ failure via early neutrophil priming and late neutrophil disability.
Topics: Adolescent; Adult; Aged; Cardiopulmonary Bypass; Female; Humans; Male; Middle Aged; Multiple Organ Failure; NADPH Oxidases; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Reactive Oxygen Species; Risk Factors; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Priming of the neutrophil respiratory burst is species-dependent and involves MAP kinase activation.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Humans; Mice; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Rabbits; Rats; Respiratory Burst; Signal Transduction; Species Specificity; Swine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1999 |
[Post-receptor formation of active forms of oxygen in nonphagocytic cells].
Topics: Animals; Cell Line; Epidermal Growth Factor; ErbB Receptors; Interferon-gamma; Lipopolysaccharides; Mice; N-Formylmethionine Leucyl-Phenylalanine; Phagocytes; Platelet Activating Factor; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1999 |
Agonist-induced adherence of equine neutrophils to fibronectin- and serum-coated plastic is CD18 dependent.
Topics: Animals; Antibodies, Monoclonal; CD18 Antigens; Cell Adhesion; Cells, Cultured; Colorimetry; Complement C5a; Fibronectins; Flow Cytometry; Horses; Interleukin-8; Male; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Platelet-activating factor induction of secreted phosphatase activity in Trypanosoma cruzi.
Topics: Animals; Azepines; Culture Media, Conditioned; Phosphoprotein Phosphatases; Platelet Activating Factor; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Sphingosine; Tetradecanoylphorbol Acetate; Time Factors; Triazoles; Trypanosoma cruzi | 1999 |
Sequential regulation of the small GTPase Rap1 in human platelets.
Topics: Antibodies, Monoclonal; Blood Platelets; Calcium; Cytoskeleton; Humans; In Vitro Techniques; Indoles; Maleimides; Platelet Activating Factor; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C; rap1 GTP-Binding Proteins; Reference Values; Tetradecanoylphorbol Acetate; Thrombasthenia; Thrombin; Type C Phospholipases | 2000 |
Differential regulation of Ca2+ influx by fMLP and PAF in human neutrophils: possible involvement of store-operated Ca2+ channel.
Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cyclic GMP; Egtazic Acid; Enzyme Activation; Humans; Imidazoles; Loperamide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Tetradecanoylphorbol Acetate | 2000 |
Phospholipase A2-mediated superoxide production of murine peritoneal macrophages induced by chrysotile stimulation.
Topics: Animals; Asbestos, Serpentine; Enzyme Inhibitors; Macrophages, Peritoneal; Male; Mice; Mice, Inbred ICR; Phospholipase A2 Inhibitors; Phospholipases A2; Platelet Activating Factor; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 2000 |
Activation of human leukocytes reduces surface P-selectin glycoprotein ligand-1 (PSGL-1, CD162) and adhesion to P-selectin in vitro.
Topics: Allergens; Asthma; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Cell Adhesion; Cell Separation; Down-Regulation; Edetic Acid; Enzyme Inhibitors; Eosinophils; Humans; L-Selectin; Leukocytes; Ligands; Membrane Glycoproteins; Monocytes; Neutrophil Activation; Neutrophils; P-Selectin; Platelet Activating Factor; Pollen; Rheology; Solubility; Tetradecanoylphorbol Acetate | 2000 |
Platelet-activating factor (PAF) modulates peritoneal mouse macrophage infection by Leishmania amazonensis.
Topics: Animals; Azepines; Female; Leishmania; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Platelet Aggregation Inhibitors; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Triazoles | 2001 |
Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia.
Topics: Adult; Blood Glucose; Calcimycin; Cells, Cultured; Cross-Sectional Studies; Diabetes Mellitus; Female; Humans; Hyperglycemia; Leukotriene B4; Lysosomes; Male; Middle Aged; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Tetradecanoylphorbol Acetate; Zymosan | 2001 |
PAF receptor antagonist modulates neutrophil responses with thermal injury in vivo.
Topics: Animals; Burns; Calcium; Carcinogens; Male; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction; Tetradecanoylphorbol Acetate | 2001 |
Activation-induced mobilization of secretory vesicles in bovine neutrophils.
Topics: Alkaline Phosphatase; Animals; Cattle; Inflammation Mediators; Interleukin-8; Leukotriene B4; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peroxidase; Platelet Activating Factor; Secretory Vesicles; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2001 |
Activated polymorphonuclear cells increase sickle red blood cell retention in lung: role of phospholipids.
Topics: Anemia, Sickle Cell; Animals; Cell Adhesion; Chromium Radioisotopes; Erythrocytes; Humans; In Vitro Techniques; Leukotriene B4; Male; NADPH Oxidases; Neutrophils; Perfusion; Phospholipids; Platelet Activating Factor; Positive-Pressure Respiration; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Tidal Volume | 2002 |
Evidence for the involvement of the NADPH oxidase enzyme complex in the optimal accumulation of Platelet-activating factor in the human cell line PLB-985.
Topics: Calcimycin; Calcium; Cell Line; Gas Chromatography-Mass Spectrometry; Glycerylphosphorylcholine; Humans; Ionophores; Leukemia, Myeloid; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Phosphatidylcholines; Platelet Activating Factor; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Superoxides; Tetradecanoylphorbol Acetate | 2001 |
Receptor-dependent metabolism of platelet-activating factor in murine macrophages.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Blotting, Western; Chromatography, Thin Layer; Concanavalin A; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genotype; Ligands; Lipid Metabolism; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Phospholipases A; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Binding; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sucrose; Tetradecanoylphorbol Acetate; Time Factors | 2002 |
Specific PAF antagonist WEB-2086 induces terminal differentiation of murine and human leukemia cells.
Topics: Animals; Antineoplastic Agents; Azepines; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Histones; HL-60 Cells; Humans; K562 Cells; Kinetics; Leukemia; Leukemia, Erythroblastic, Acute; Mice; Phospholipid Ethers; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Triazoles; Tumor Cells, Cultured | 2002 |
Effects of platelet activating factor, butyrate and interleukin-6 on cyclooxygenase-2 expression in human esophageal cancer cells.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Butyrates; Carcinoma, Squamous Cell; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Esophageal Neoplasms; Female; Humans; Immunohistochemistry; Interleukin-6; Isoenzymes; Male; Membrane Proteins; Middle Aged; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandin-Endoperoxide Synthases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Platelet-activating factor priming of inflammatory cell activity requires cellular adherence.
Topics: Calcium; Carcinogens; Cell Adhesion; Cell Differentiation; Humans; In Vitro Techniques; Inflammation Mediators; Interleukin-1 Receptor-Associated Kinases; Lipopolysaccharides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tetradecanoylphorbol Acetate; Vitamin D | 2002 |
In vitro effects of ginkgolide B combined with cyclosporin A on T-lymphocyte activation and IL-5 expression in peripheral blood mononuclear cells from asthmatic subjects.
Topics: Adult; Asthma; Cells, Cultured; Cyclosporine; Cytokines; Diterpenes; Female; Flow Cytometry; Ginkgolides; Humans; In Vitro Techniques; Interleukin-5; Kuwait; Lactones; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Phytotherapy; Platelet Activating Factor; T-Lymphocytes; Tetradecanoylphorbol Acetate | 2002 |
Cyclooxygenase-2 in human non-small cell lung cancer.
Topics: Aged; Butyrates; Carcinoma, Non-Small-Cell Lung; Cyclooxygenase 2; Female; Humans; Immunoblotting; Immunohistochemistry; Inflammation Mediators; Isoenzymes; Lung Neoplasms; Male; Membrane Proteins; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
Inhibitory effects of glucocorticoids on rat eosinophil superoxide generation and chemotaxis.
Topics: Animals; Beclomethasone; Cells, Cultured; Chemotaxis, Leukocyte; Dexamethasone; Eosinophils; Glucocorticoids; In Vitro Techniques; Leukocyte Count; Leukotriene B4; Male; Mometasone Furoate; Platelet Activating Factor; Pregnadienediols; Rats; Rats, Sprague-Dawley; Superoxides; Tetradecanoylphorbol Acetate | 2003 |
Regulation and kinetics of platelet-activating factor and leukotriene C4 synthesis by activated human basophils.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Arachidonic Acids; Basophils; Cells, Cultured; Complement C5a; Enzyme Inhibitors; Humans; Interleukin-3; Leukotriene C4; N-Formylmethionine Leucyl-Phenylalanine; Organophosphonates; Phospholipases A2; Platelet Activating Factor; Receptors, IgE; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2003 |
Phorbol myristate acetate stimulates degradation of a structural analogue of platelet-activating factor to a neutral lipid in human leukemic K562 cells: relevance to the release of lipids.
Topics: Biotransformation; Bridged-Ring Compounds; Chromatography, Thin Layer; Culture Media; Humans; K562 Cells; Lipid Metabolism; Lipids; Norbornanes; Platelet Activating Factor; Sodium Fluoride; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thiocarbamates; Thiones | 2004 |
Platelet-activating factor stimulates cytoplasmic alkalinization and granule acidification in human eosinophils.
Topics: Adenosine Triphosphatases; Blotting, Western; Calcium; Cell Adhesion; Cell Membrane; Cells, Cultured; Cytoplasm; Cytoplasmic Granules; Cytosol; Eosinophil Granule Proteins; Eosinophil Major Basic Protein; Eosinophils; Esters; Fluoresceins; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Interleukin-5; Microscopy, Fluorescence; Oligonucleotide Array Sequence Analysis; Platelet Activating Factor; Protein Kinase C; Protons; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Vacuolar Proton-Translocating ATPases; Zinc | 2004 |
Calcium-independent phospholipase A2 is regulated by a novel protein kinase C in human coronary artery endothelial cells.
Topics: Arachidonic Acid; Cell Membrane; Cells, Cultured; Coronary Vessels; Endothelial Cells; Enzyme Activation; Group VI Phospholipases A2; Humans; Immunoblotting; Phospholipases A; Phospholipases A2; Phospholipids; Platelet Activating Factor; Polymerase Chain Reaction; Protein Isoforms; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin | 2005 |
Lysophosphatidylcholine modulates neutrophil oxidant production through elevation of cyclic AMP.
Topics: Animals; Capillary Permeability; CD11b Antigen; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Humans; In Vitro Techniques; Lung; Lysophosphatidylcholines; Mice; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Oxidants; Phosphoproteins; Platelet Activating Factor; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Superoxides; Tetradecanoylphorbol Acetate; Up-Regulation | 2005 |
Evaluation of in-vitro anti-inflammatory activity of some 2-alkyl-4,6-dimethoxy-1,3,5-triazines.
Topics: Anti-Inflammatory Agents; Cell Adhesion; Cells, Cultured; Endothelial Cells; Humans; Interleukin-1; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Superoxides; Tetradecanoylphorbol Acetate; Triazines; Tumor Necrosis Factor-alpha | 2006 |
Respiratory burst function of ovine neutrophils.
Topics: Animals; Immunity, Innate; Immunologic Techniques; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophil Activation; Neutrophils; Platelet Activating Factor; Reactive Oxygen Species; Respiratory Burst; Sheep; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 2009 |
Persistency and pathway of isoflurane-induced inhibition of superoxide production by neutrophils.
Topics: Anesthetics, Inhalation; Animals; Calcimycin; Dogs; Isoflurane; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activating Factor; Protein Kinase C; Signal Transduction; Spectrophotometry; Superoxides; Tetradecanoylphorbol Acetate; Time Factors | 2010 |
Loss of the platelet activating factor receptor in mice augments PMA-induced inflammation and cutaneous chemical carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 2012 |
Differential inhibitory effects of 2-azafluorenones on PI-PLC activation but not on PC-PLC- or PC-PLD-activation induced by histamine, PAF, PMA or A23187 in C6 glioma cells.
Topics: Animals; Calcimycin; Cell Line, Tumor; Enzyme Activation; Fluorenes; Histamine; Phosphatidylcholines; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phospholipase D; Platelet Activating Factor; Rats; Tetradecanoylphorbol Acetate; Tritium; Type C Phospholipases | 2013 |
Dimethyl fumarate modulates neutrophil extracellular trap formation in a glutathione- and superoxide-dependent manner.
Topics: Analysis of Variance; Antioxidants; Caspases; Cells, Cultured; Dermatologic Agents; Dimethyl Fumarate; Dose-Response Relationship, Drug; Extracellular Traps; Fumarates; Glutathione; GTP-Binding Proteins; Humans; Ionomycin; Platelet Activating Factor; Psoriasis; Reactive Oxygen Species; Superoxides; Tetradecanoylphorbol Acetate | 2018 |