tetradecanoylphorbol acetate has been researched along with 1,2-dioctanoylglycerol in 219 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 79 (36.07) | 18.7374 |
| 1990's | 125 (57.08) | 18.2507 |
| 2000's | 12 (5.48) | 29.6817 |
| 2010's | 3 (1.37) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crook, RB; Yabu, JM | 1 |
| Boscá, L; Genaro, AM; Hortelano, S | 1 |
| Akimaru, K; Edashige, K; Klostergaard, J; Sato, EF; Utsumi, K; Utsumi, T | 1 |
| Grinstein, S; Gukovskaya, A; Nanda, A; Tseng, J | 1 |
| Endo, Y; Furuya, S; Matsui, Y; Nozawa, S; Oba, M; Suzuki, S | 1 |
| Endo, Y; Furuya, S; Nozawa, S; Oba, M; Suzuki, S | 1 |
| Chan, CK; Downey, GP; Grinstein, S; Lea, P; Takai, A | 1 |
| Luna, EJ; Shariff, A | 1 |
| Larsson, C; Mau, S; Saermark, T; Simonsson, P | 1 |
| Chang, JP; Jobin, RM | 1 |
| Bour, BA; Grove, DS; Mastro, AM; Stanek, EM | 1 |
| Schrier, RW; Williams, B | 1 |
| Arias, R; Barreto, A; Butler, B; Chan, WW; Cheng, K | 1 |
| Nitsch, RM; Richardson, UI; Slack, BE; Wurtman, RJ | 1 |
| Howe, RC; MacDonald, HR; Stoeck, M | 1 |
| Brachet, P; Houlgatte, R; Jehan, F; Neveu, I; Wion, D | 1 |
| Bierman, EL; Mendez, AJ; Oram, JF | 1 |
| Civan, MM; George, K; O'Brien, TG; Oler, A; Peterson-Yantorno, K | 1 |
| Mohsenin, V; Yoshida, K | 2 |
| Bordier, C; Cassar, G; Chiron, M; Darbon, JM; Jaffrezou, JP; Laurent, G; Roubinet, F | 1 |
| Gárdos, G; Müller, M; Sarkadi, B; Tordai, A | 1 |
| Johnson, AL; Tilly, JL | 1 |
| Grenfell, S; Ray, K; Rollins, P; Sadler, H; Smithers, N; Solari, R; Thompson, N; Witham, S | 1 |
| Grinstein, S; Nanda, A | 1 |
| Donoghue, DJ; Scanes, CG | 1 |
| Huang, CL; Ives, HE; Weiss, RH | 1 |
| Aihara, H; Asaoka, Y; Nishizuka, Y; Yoshida, K | 1 |
| Casillas, T; Delicado, EG; Miras-Portugal, MT; Sen, RP | 1 |
| Elstad, MR; McIntyre, TM; Prescott, SM; Zimmerman, GA | 1 |
| Mate, KE; Rodger, JC | 1 |
| Khan, NA; Moulinoux, JP; Quemener, V | 1 |
| Doré, M; Neilsen, NR; Slauson, DO | 1 |
| Ashendel, CL; Molina, CA | 1 |
| Gould-Fogerite, S; Mannino, RJ; Reston, JT | 1 |
| Lobo, MV; Marusic, ET | 1 |
| Cianciolo, GJ; Kadota, J; Snyderman, R | 1 |
| French, MB; Kraicer, J; Lussier, BT; Moor, BC | 1 |
| Edes, I; Kranias, EG | 2 |
| Martin, DB; Pek, SB; Thomas, TP | 1 |
| Harnish, DG; Polyak, SJ; Rawls, WE | 1 |
| Bement, WM; Capco, DG | 1 |
| McMurtry, IF; Orton, EC; Raffestin, B | 1 |
| Emilsson, A; Sundler, R; Wijkander, J | 2 |
| Akiba, S; Fujii, T; Sato, T | 1 |
| Karin, M; Kraft, AS; Wagner, F; William, F | 1 |
| Marquardt, DL; Walker, LL | 1 |
| Kolesnick, RN | 1 |
| Huang, CL; Ives, HE; Lowe, JH | 1 |
| Kamel, F; Krey, LC | 1 |
| Goto, H; Matsui-Yuasa, I; Morisawa, S; Otani, S | 1 |
| Hemer, MR; Kolesnick, RN | 1 |
| Endou, H; Satoh, T | 1 |
| Badwey, JA; Heyworth, PG; Robinson, JM | 1 |
| French, JT; Welsh, TH | 1 |
| Gobran, LI; Rooney, SA | 3 |
| Ase, K; Berry, N; Kishimoto, A; Nishizuka, Y | 1 |
| Capogrossi, MC; Filburn, CR; Hansford, RG; Kaku, T; Lakatta, EG; Pelto, DJ; Spurgeon, HA | 1 |
| Goppelt-Strübe, M; Möller, A | 1 |
| Godson, C; Insel, PA; Weiss, BA | 1 |
| Cherqui, G; Lévy, P; Picard, J; Robert, A; Wicek, D | 1 |
| Conroy, MC; Kennedy, JA; Thueson, DO; Wright, CD | 1 |
| Haslam, RJ; Murphy, W; Williams, KA | 1 |
| Bergstrand, H; Lundquist, B; Michelsen, P | 1 |
| Alonso, M; Cárdenas, L; Carrera, AC; de Landázuri, MO; Sánchez-Madrid, F; Tugores, A | 1 |
| Kitajima, Y; Sheu, HM; Yaoita, H | 1 |
| Igusa, Y; Miyazaki, S; Swann, K | 1 |
| Fitch, FW; Hui, FH; Kim, DK; Lancki, DW | 1 |
| Nath, J; Powledge, A; Wright, DG | 1 |
| Chen, TH; Gagucas, R; Membreño, L; Shoback, D; Woodley, S | 1 |
| Greene, DA; Lattimer, SA; Sima, AA | 1 |
| Badwey, JA; Heyworth, PG; Karnovsky, ML | 1 |
| Gillies, RJ; Hoyer, PB; Martinez, R; Sneider, JM | 1 |
| Bjorndahl, JM; Fu, SM; Hansen, JA; Sung, SS | 1 |
| Kakkar, VV; Krishnamurthi, S; Morgan, WA | 1 |
| Kakkar, VV; Krishnamurthi, S; Morgan, WA; Patel, Y; Wheeler-Jones, CP | 1 |
| Castro, MG; Gusovsky, F; Loh, YP | 1 |
| Badwey, JA; Curnutte, JT; Heyworth, PG; Robinson, JM | 1 |
| Bonfil, RD; Fridman, R; Harris, CC; Klein-Szanto, A; Momiki, S; Reddel, R; Reich, R | 1 |
| Mills, KJ; Smart, RC | 1 |
| Kaever, V; Pfannkuche, HJ; Resch, K; Wessel, K | 1 |
| Maier, JA; Presta, M; Ragnotti, G | 1 |
| Inoue, Y; Rebois, RV | 1 |
| Acevedo-Duncan, M; Cooper, DR; Farese, RV; Pollet, RJ; Standaert, ML; Watson, JE | 1 |
| Conney, AH; Hansen, LA; Mills, KJ; Smart, RC | 1 |
| Knauf, PA; Kozody, DJ; Restrepo, D | 1 |
| Lees, R; MacDonald, HR; Pantaleo, G; Stoeck, M; Szamel, M | 1 |
| Gárdos, G; Görög, G; Sarkadi, B; Tordai, A | 1 |
| Auwerx, JH; Chait, A; Deeb, SS; Wolfbauer, G | 1 |
| Griffor, MC; Scarpa, A; Wiener, EC | 1 |
| Jarvis, WD; Judd, AM; MacLeod, RM | 1 |
| Dougherty, RW; Niedel, JE; Rider, LG | 1 |
| Baum, M; Hays, SR | 1 |
| Conn, PM; Huckle, WR; McArdle, CA | 1 |
| Joseph, S; Kakkar, VV; Krishnamurthi, S | 2 |
| Clegg, S; Kolesnick, RN | 1 |
| Drucker, DJ; Habener, JF; Philippe, J | 1 |
| Murthi, VK; Sehajpal, P; Stenzel, KH; Subramaniam, A; Suthanthiran, M | 1 |
| Perianin, A; Synderman, R | 1 |
| Bell, RM; Czech, MP; Davis, RJ; Ganong, BR | 1 |
| Abou-Samra, AB; Aguilera, G; Catt, KJ | 2 |
| Greene, DA; Lattimer, SA | 1 |
| Gainer, HS; Murray, AW | 1 |
| Jetten, AM; Shirley, JE | 1 |
| Chu, DT; Granner, DK | 1 |
| Brami, B; Chambaz, EM; Vilgrain, I | 1 |
| Glomset, JA; Goerig, M; Habenicht, AJ; Heitz, R; Katus, H; Kommerell, B; Zeh, W; Ziegler, R | 1 |
| Catt, KJ; Chang, JP; Graeter, J | 1 |
| Albert, PR; Tashjian, AH; Wolfson, G | 1 |
| Conn, PM; Wooge, CH | 1 |
| Kreutter, D; Morin, MJ; Rasmussen, H; Sartorelli, AC | 1 |
| Cloyd, MW; Lynn, WS; Tweedale, A | 1 |
| Bruni, P; Farnararo, M; Vasta, V | 1 |
| Catt, KJ; Chang, JP; Morgan, RO | 1 |
| Baker, RL; Erbland, JF; McKinney, RV; Schuster, GS; Singh, BB | 1 |
| Akerman, KE; Heikkilä, JE; Jalava, AM | 1 |
| George, K; O'Brien, TG; Prettyman, R | 1 |
| Bayard, F; Darbon, JM; Issandou, M | 1 |
| O'Flaherty, JT; Rossi, AG; Thomas, MJ | 1 |
| Akerman, KE; Enkvist, MO; Holopainen, I | 1 |
| Fu, SM; Jung, LK | 1 |
| Dinh, TH; Magun, BE; Muldoon, LL; Rodland, KD | 1 |
| Civan, MM; O'Brien, TG; Peterson-Yantorno, K | 2 |
| Jackson, GL; Liu, TC | 1 |
| Darbon, JM; Issandou, M | 1 |
| Morrow, C; Murphy, S; Pearce, B | 1 |
| Niedel, JE; Salehi, Z; Taylor, JD | 1 |
| Muir, JG; Murray, AW | 1 |
| Erne, P; Fabbro, D; Miles, CM; Schachter, M; Sever, PS | 1 |
| Kolesnick, RN; Paley, AE | 1 |
| Bruns, C; Marmé, D; Schächtele, C | 1 |
| Baum, M; Hays, SR; Kokko, JP | 1 |
| Blusztajn, JK; Liscovitch, M; Slack, B; Wurtman, RJ | 1 |
| Bell, RM; Ganong, B; Handwerger, S; Harman, I; Zeitler, P | 1 |
| Blackshear, PJ; Halsey, DL; Hovis, JG; Stumpo, DJ | 1 |
| Endo, Y; Kopf, GS; Schultz, RM | 1 |
| Kawahara, Y; Nakayama, I; Okuda, M; Tsuda, T; Yokoyama, M | 1 |
| Chandler, LJ; Davda, RK; Guzman, NJ | 1 |
| Mau, SE; Saermark, T; Vilhardt, H | 1 |
| Asaoka, Y; Chang, WC; Liu, YW; Suzuki, H; Yamamoto, S; Yoshimoto, T | 1 |
| Kaila, K; Pasternack, M; Törnquist, K | 1 |
| Heiskanen, KM; Naarala, J; Savolainen, KM | 1 |
| Overstreet, JW; Tollner, TL; VandeVoort, CA | 1 |
| Akard, L; Cui, Y; English, D; Garcia, JG; Harvey, K; Jansen, J; Martin, MI; Siddiqui, RA; Thompson, J; Wentland, J | 1 |
| Kopf, GS; Moore, GD; Schultz, RM | 1 |
| Anderson, RA; Drisdel, RC; Mack, SR; Zaneveld, LJ | 1 |
| Mueller, SG; Richmond, A; Schraw, WP | 1 |
| Apgar, JR | 1 |
| Huang, D; Jungmann, RA | 1 |
| Aptel, HB; Burnay, MM; Capponi, AM; Python, CP; Rossier, MF; Vallotton, MB | 1 |
| Boland, R; Marinissen, MJ; Selles, J | 1 |
| Bruni, P; Farnararo, M; Meacci, E; Vannini, F; Vasta, V | 1 |
| Bendayan, M; Goresky, CA; Rasio, EA | 1 |
| Murthy, M; Rao, GH; Reddy, S | 1 |
| Berkovic, D; Berkovic, K; Eibl, H; Fleer, EA; Unger, C | 1 |
| Asaoka, Y; Nishizuka, Y; Tsujishita, Y | 1 |
| Hymer, TK; Katz, MS; Kitten, AM | 1 |
| Nachmias, VT; Niu, MY | 1 |
| Brooks, G; East, JA; Goss, MW; Hart, IR | 1 |
| Krämer, K; Markwitan, A; Pallauf, J | 1 |
| Exton, JH; Ha, KS | 2 |
| Kelly, PA; Lee, CS; Ormandy, CJ; Sutherland, RL | 1 |
| Kosaka, C; Masuda, J; Ogata, J; Sasaguri, T; Shimokado, K; Yokota, T; Zen, K | 1 |
| Teitelbaum, I | 1 |
| Ching, KN; Nicholson, WE; Orth, DN; Won, JG | 1 |
| Ayuso, MS; Butta, N; Ciprés, G; Manchón, CG; Parrilla, R; Requero, AM; Urcelay, E | 1 |
| Capco, DG; Gallicano, GI; McGaughey, RW; Schwarz, SM | 1 |
| Heiskanen, K; Ruotsalainen, M; Savolainen, K | 1 |
| Calonge, ML; Ilundáin, AA | 1 |
| Berggren, PO; Bokvist, K; Chheda, S; Corkey, BE; Cunningham, BA; Deeney, JT; Juntti-Berggren, L; Korchak, HM; Lam, K | 1 |
| Copeland, BJ; Hadjiconstantinou, M; Neff, NH; Vogelsberg, V | 1 |
| Liu, S; Schreur, KD | 1 |
| Chang, JP; Jobin, RM; Neumann, CM; Van Goor, F | 1 |
| Tóth, M | 1 |
| Farooq, M; Larocca, JN; Norton, WT | 1 |
| Braiman, A; Levin, R; Priel, Z | 1 |
| Badwey, JA; Ding, J; Ellis, BA; Heyworth, PG; Robinson, JM | 1 |
| Brodsky, I; Danilenko, M; Gertsberg, I; Priel, Z | 1 |
| Bonev, AD; Jaggar, JH; Nelson, MT; Rubart, M | 1 |
| Devonish, W; Foster, DA; Hornia, A; Liu, D; Lu, Z; Pagano, M | 1 |
| Meyer, T; Oancea, E; Quest, AF; Teruel, MN | 1 |
| Devor, DC; Frizzell, RA | 1 |
| Reshef, A; Sperling, O; Zoref-Shani, E | 1 |
| Boland, R; Capiati, D; Marinissen, MJ | 1 |
| Bohnsack, JF; Rowin, ME; Whatley, RE; Yednock, T | 1 |
| Lippe, WR; Rubel, EW; Zirpel, L | 1 |
| Kurota, H; Yamaguchi, M | 1 |
| Anderson, WH; Crilly, KS; Kiss, Z | 1 |
| Dyer, D; McCloud, E; Moyer, MP; Ortiz, A; Rubin, S; Said, HM | 1 |
| Chaban, VV; Dirksen, ER; Woodruff, ML; Worley, CM | 1 |
| Namiki, H; Suzuki, K | 1 |
| Blom, M; Roos, D; Tool, AT; Verhoeven, AJ | 1 |
| Martinez, JR; Sun, X; Zhang, GH | 1 |
| Bednarczyk, D; Dantzler, WH; Gekle, M; Mildenberger, S; Sauvant, C; Wright, SH | 1 |
| McPhail, LC; Nixon, JB | 1 |
| Durieux, ME; Kamatchi, GL; Lynch, C; Tiwari, SN | 1 |
| He, JQ; Kamp, TJ; Pi, Y; Walker, JW | 1 |
| Djiane, J; Sorin, B; Vacher, AM; Vacher, P | 1 |
| Hymer, TK; Katz, MS; Lifschitz, MD; Yeh, CK; Zhang, BX | 1 |
| Chen, DY; Han, ZM; Lu, Q; Schatten, H; Smith, GD; Sun, QY; Yang, Z | 1 |
| Andreeva, AY; Blasig, IE; Krause, E; Müller, EC; Utepbergenov, DI | 1 |
| Chen, DY; Han, ZM; Lu, Q; Smith, GD; Sun, QY | 1 |
| Chen, DY; Fan, HY; Li, MY; Schatten, H; Song, XF; Sun, QY; Tong, C; Xia, GL | 1 |
| Ciereszko, RE; Dusza, L; Kaminska, B; Opalka, M | 1 |
| Braun, S; Catt, KJ; Dautzenberg, FM; Hauger, RL; Olivares-Reyes, JA | 1 |
| Courjaret, R; Grolleau, F; Lapied, B | 1 |
| Faherty, S; Kane, MT; Quinlan, LR | 1 |
| Hu, T; Liu, Z; Shen, X | 1 |
| Barger, CJ; Black, AR; Black, JD; Hsu, AH; Leontieva, OV; Lum, MA | 1 |
| Kerr, DE; Kissinger, LF; Shoyab, M | 1 |
| Das, J; Majhi, A; Panchal, S; Rahman, GM | 1 |
219 other study(ies) available for tetradecanoylphorbol acetate and 1,2-dioctanoylglycerol
| Article | Year |
|---|---|
Calcitonin gene-related peptide stimulates intracellular cAMP via a protein kinase C-controlled mechanism in human ocular ciliary epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Calcitonin; Calcitonin Gene-Related Peptide; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Epithelium; Eye; Fetus; Humans; Kinetics; Phorbol Esters; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Phorbol esters induce nitric oxide synthase activity in rat hepatocytes. Antagonism with the induction elicited by lipopolysaccharide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carcinogens; Cells, Cultured; Cyclic GMP; Diglycerides; Enzyme Induction; Kinetics; Lipopolysaccharides; Liver; Nitric Oxide Synthase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Tetradecanoylphorbol Acetate | 1992 |
Modulation of TNF-alpha-priming and stimulation-dependent superoxide generation in human neutrophils by protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Cinnamates; Diglycerides; Genistein; Guinea Pigs; Humans; Isoflavones; Isoquinolines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Opsonin Proteins; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Recombinant Proteins; Staurosporine; Sulfides; Superoxides; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha; Zymosan | 1992 |
Activation of vacuolar-type proton pumps by protein kinase C. Role in neutrophil pH regulation.
Topics: Adult; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carrier Proteins; Cell Membrane; Cytosol; Diglycerides; Fluoresceins; Homeostasis; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Neutrophils; Onium Compounds; Protein Kinase C; Proton-Translocating ATPases; Sodium-Hydrogen Exchangers; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate; Vacuoles; Valinomycin | 1992 |
Protein phosphorylation regulates the mouse sperm acrosome reaction induced by the zona pellucida.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acrosome; Alkaloids; Animals; Diglycerides; Ethers, Cyclic; Exocytosis; Female; Genistein; Isoflavones; Isoquinolines; Male; Membrane Fusion; Mice; Okadaic Acid; Phorbol Esters; Phosphoprotein Phosphatases; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Protein Processing, Post-Translational; Signal Transduction; Sperm-Ovum Interactions; Staurosporine; Tetradecanoylphorbol Acetate; Zona Pellucida | 1992 |
Effects of modulators of protein kinases and phosphatases on mouse sperm capacitation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Bucladesine; Chlortetracycline; Dibutyryl Cyclic GMP; Diglycerides; Ethers, Cyclic; Fluorescence; Genistein; Isoflavones; Isoquinolines; Male; Mice; Okadaic Acid; Peptide Fragments; Phorbol Esters; Phosphoprotein Phosphatases; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Sperm Capacitation; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Phorbol ester-induced actin assembly in neutrophils: role of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Cell Membrane; Diglycerides; Enzyme Activation; Humans; Isoquinolines; Microscopy, Electron, Scanning; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Naphthalenes; Neutrophils; Piperazines; Polycyclic Compounds; Protein Kinase C; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate | 1992 |
Diacylglycerol-stimulated formation of actin nucleation sites at plasma membranes.
Topics: Actins; Alkaloids; Animals; Calcium; Cell Membrane; Dictyostelium; Diglycerides; Kinetics; Macromolecular Substances; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors | 1992 |
Activation of protein kinase C in permeabilized human neuroblastoma SH-SY5Y cells.
Topics: Acetophenones; Amino Acid Sequence; Arachidonic Acids; Calcium; Cell Membrane; Cell Membrane Permeability; Digitonin; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Molecular Sequence Data; Myelin Basic Protein; Neuroblastoma; Phospholipases A; Phospholipases A2; Phosphorus; Phosphorus Radioisotopes; Phosphorylation; Protein Kinase C; Quinacrine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Actions of two native GnRHs and protein kinase C modulators on goldfish pituitary cells. Studies on intracellular calcium levels and gonadotropin release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Biological Transport; Calcimycin; Calcium; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Fluorescence; Fura-2; Goldfish; Gonadotropin-Releasing Hormone; Pituitary Gland; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil | 1992 |
Cytochalasans and PMA induce IL-2 receptors on CD8+ lymphocytes.
Topics: Animals; Antibodies, Monoclonal; Cattle; CD8 Antigens; Cells, Cultured; Colchicine; Cycloheximide; Cytochalasin B; Cytochalasin D; Diglycerides; Flow Cytometry; Interleukin-2; Receptors, Interleukin-2; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1992 |
Characterization of glucose-induced in situ protein kinase C activity in cultured vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Analysis of Variance; Angiotensin II; Animals; Aorta; Arginine Vasopressin; Cell Membrane Permeability; Cells, Cultured; Digitonin; Diglycerides; Enzyme Activation; Glucose; Isoquinolines; Kinetics; Molecular Sequence Data; Muscle, Smooth, Vascular; Oligopeptides; Phosphorylation; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1992 |
PMA-sensitive protein kinase C is not necessary in TRH-stimulated prolactin release from female rat primary pituitary cells.
Topics: Animals; Calcium; Cells, Cultured; Colforsin; Diglycerides; Down-Regulation; Enzyme Activation; Female; Pituitary Gland, Anterior; Prolactin; Protein Kinase C; Radioimmunoassay; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1992 |
Dioctanoylglycerol stimulates accumulation of [methyl-14C]choline and its incorporation into acetylcholine and phosphatidylcholine in a human cholinergic neuroblastoma cell line.
Topics: Acetylcholine; Choline; Diglycerides; Humans; Nervous System Neoplasms; Neuroblastoma; Osmolar Concentration; Parasympathetic Nervous System; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |
Distinct effects of phorbol esters and exogenous diacylglycerols in the induction of murine thymocyte proliferation.
Topics: Animals; Cell Division; Cells, Cultured; Diglycerides; Flow Cytometry; Interleukin-1; Interleukin-2; Mice; Mice, Inbred C57BL; Nigericin; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thymus Gland | 1992 |
Activation of nerve growth factor synthesis in primary glial cells by phorbol 12-myristate 13-acetate: role of protein kinase C.
Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Culture Media; Dexamethasone; Diglycerides; Mice; Nerve Growth Factors; Neuroglia; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1992 |
Protein kinase C as a mediator of high density lipoprotein receptor-dependent efflux of intracellular cholesterol.
Topics: Apolipoprotein A-I; Apolipoproteins A; Biological Transport; Calcimycin; Carrier Proteins; Cell Membrane; Cells, Cultured; Cholesterol; Diglycerides; Down-Regulation; Enzyme Activation; Humans; Lipoproteins, HDL; Protein Kinase C; Receptors, Cell Surface; Receptors, Lipoprotein; RNA-Binding Proteins; Skin; Sphingosine; Tetradecanoylphorbol Acetate | 1991 |
Ca(2+)-independent form of protein kinase C may regulate Na+ transport across frog skin.
Topics: Amiloride; Amino Acid Sequence; Animals; Biological Transport, Active; Cadmium; Calcium; Cobalt; Cyclic AMP; Diglycerides; Epithelium; Gallic Acid; Insulin; Kinetics; Molecular Sequence Data; Mucous Membrane; Protein Kinase C; Rana pipiens; Skin; Sodium; Sodium Channels; Tetradecanoylphorbol Acetate | 1991 |
Unsaturated phosphatidylcholines inhibit superoxide production in human neutrophils.
Topics: Analysis of Variance; Cell Fractionation; Diglycerides; Enzyme Activation; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylcholines; Protein Kinases; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Quantitative analysis of CD5 antigen modulation by 12-O-tetradecanoylphorbol-13-acetate in T-lymphoblastic leukemia cells: individual response patterns and their relationships with both maturation and protein kinase C content.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Differentiation; Antigens, Differentiation, T-Lymphocyte; CD5 Antigens; Cell Cycle; Cell Differentiation; Cell Division; Diglycerides; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Leukemia, T-Cell; Phenotype; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Regulation of stimulus-induced calcium transport pathways in human T (Jurkat) lymphoblasts.
Topics: 4-Chloromercuribenzenesulfonate; Antibodies, Monoclonal; Benzothiazoles; Biological Transport; Calcium; Carbocyanines; Cell Line; Diglycerides; Gramicidin; Humans; Membrane Potentials; Muromonab-CD3; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Second messenger pathways mediating chicken luteinizing hormone secretion from dispersed pituitary cells.
Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Animals; Arachidonic Acids; Calcimycin; Calcium; Carcinogens; Chickens; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Male; Pituitary Gland; Protein Kinase C; Second Messenger Systems; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Transforming Growth Factor alpha | 1991 |
Modification of biological responses to interleukin-1 by agents that perturb signal transduction pathways.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diglycerides; Dinoprostone; Flow Cytometry; Interleukin-1; Interleukin-2; Lymphocyte Activation; Mice; Pertussis Toxin; Protein Kinase C; Recombinant Proteins; Signal Transduction; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
Protein kinase C activates an H+ (equivalent) conductance in the plasma membrane of human neutrophils.
Topics: Alkaloids; Cell Membrane; Diglycerides; Diterpenes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Neutrophils; Potassium; Protein Kinase C; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate; Valinomycin | 1991 |
Triiodothyronine (T3) inhibition of growth hormone secretion by chicken pituitary cells in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Calcimycin; Cells, Cultured; Chickens; Colforsin; Diglycerides; Dose-Response Relationship, Drug; Growth Hormone; Growth Hormone-Releasing Hormone; In Vitro Techniques; Male; Pituitary Gland, Anterior; Radioimmunoassay; Second Messenger Systems; Tetradecanoylphorbol Acetate; Triiodothyronine | 1991 |
Sphingosine reverses growth inhibition caused by activation of protein kinase C in vascular smooth muscle cells.
Topics: Animals; Cell Division; Cells, Cultured; Diglycerides; DNA; Enzyme Activation; Muscle, Smooth, Vascular; Protein Kinase C; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Thrombin | 1991 |
Sustained activation of protein kinase C is essential to HL-60 cell differentiation to macrophage.
Topics: Biological Transport; Cell Differentiation; Cell Line; Diglycerides; Enzyme Activation; Flow Cytometry; Humans; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Macrophage-1 Antigen; Macrophages; Phagocytosis; Protein Kinase C; Tetradecanoylphorbol Acetate | 1991 |
Control of nucleoside transport in neural cells. Effect of protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine; Adrenal Medulla; Animals; Biological Transport; Calcimycin; Caprylates; Cells, Cultured; Diglycerides; Dinucleoside Phosphates; Enzyme Activation; Ethers, Cyclic; Isoquinolines; Kinetics; Okadaic Acid; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Triglycerides | 1991 |
Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes.
Topics: Binding Sites; Calcimycin; Diglycerides; Enzyme Activation; Humans; Kinetics; Leukotriene B4; Monocytes; Opsonin Proteins; Phagocytosis; Platelet Activating Factor; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Zymosan | 1991 |
Stability of the acrosome of the brush-tailed possum (Trichosurus vulpecula) and tammar wallaby (Macropus eugenii) in vitro and after exposure to conditions and agents known to cause capacitation or acrosome reaction of eutherian spermatozoa.
Topics: Acrosome; Animals; Bucladesine; Calcimycin; Cell Membrane; Cells, Cultured; Dibutyryl Cyclic GMP; Diglycerides; Lysophosphatidylcholines; Macropodidae; Male; Marsupialia; Microscopy, Electron; Sperm Capacitation; Spermatozoa; Tetradecanoylphorbol Acetate; Trypsin | 1991 |
Exogeneous diacylglycerols downregulate the activity of Na(+)-K+ pump in Xenopus laevis oocytes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amiloride; Animals; Biological Transport, Active; Cell Membrane; Diglycerides; Female; In Vitro Techniques; Isoquinolines; Kinetics; Oocytes; Piperazines; Protein Kinase C; Rubidium; Sodium; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate; Xenopus laevis | 1991 |
Decreased respiratory burst activity in neonatal bovine neutrophils stimulated by protein kinase C agonists.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Cattle; Cells, Cultured; Diglycerides; Dose-Response Relationship, Drug; Female; Isoquinolines; Neutrophils; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1991 |
Tumor promoter 12-O-tetradecanoylphorbol-13-acetate and sn-1,2-dioctanoylglycerol increase the phosphorylation of protein kinase C in cells.
Topics: Animals; Brain; Cell Line, Transformed; Diglycerides; Enzyme Activation; Molecular Weight; Peptide Mapping; Phosphorylation; Precipitin Tests; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1991 |
Potentiation of DNA mediated gene transfer in NIH3T3 cells by activators of protein kinase C.
Topics: Animals; beta-Galactosidase; Calcium Phosphates; Cell Line; Diglycerides; DNA; Enzyme Activation; Gene Expression; Mice; Phorbol Esters; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection | 1991 |
Contrasting effects of sn-1,2-dioctanoyl glycerol as compared to other protein kinase C activators in adrenal glomerulosa cells.
Topics: Aldosterone; Alkaloids; Angiotensin II; Animals; Biological Transport; Cattle; Cell Membrane Permeability; Diglycerides; Enzyme Activation; Potassium; Protein Kinase C; Rubidium; Staurosporine; Tetradecanoylphorbol Acetate; Zona Glomerulosa | 1991 |
A synthetic peptide homologous to retroviral transmembrane envelope proteins depresses protein kinase C mediated lymphocyte proliferation and directly inactivated protein kinase C: a potential mechanism for immunosuppression.
Topics: Amino Acid Sequence; Diglycerides; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Immunosuppression Therapy; Intercellular Signaling Peptides and Proteins; Lymphocyte Activation; Molecular Sequence Data; Neutrophils; Peptides; Protein Kinase C; Retroviridae Proteins, Oncogenic; Tetradecanoylphorbol Acetate; Viral Envelope Proteins | 1991 |
Growth hormone-releasing factor does not activate protein kinase C in somatotrophs.
Topics: Amino Acid Sequence; Animals; Chromatography, DEAE-Cellulose; Diglycerides; Enzyme Activation; Growth Hormone-Releasing Hormone; Kinetics; Male; Molecular Sequence Data; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Substrate Specificity; Tetradecanoylphorbol Acetate | 1991 |
The effect of phorbol esters and diacylglycerol analogues on the basal phosphoinositide turnover in isolated guinea pig hearts.
Topics: Animals; Diglycerides; Guinea Pigs; Heart; In Vitro Techniques; Myocardial Contraction; Myocardium; Perfusion; Phosphatidylinositols; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1990 |
Dioctanoylglycerol regulation of cytosolic Ca2+ by protein kinase C-independent mechanism in HIT T-15 islet cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Calcium; Cricetinae; Cytosol; Diglycerides; Ethanol; Islets of Langerhans; Isoquinolines; Kinetics; Mesocricetus; Piperazines; Protein Kinase C; Spectrometry, Fluorescence; Sphingosine; Staurosporine; Tetradecanoylphorbol Acetate; Verapamil | 1991 |
Characterization of Pichinde virus infection of cells of the monocytic lineage.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antigens, Viral; Arenaviridae; Cell Differentiation; Cells, Cultured; Diglycerides; Humans; In Vitro Techniques; Isoquinolines; Monocytes; Piperazines; Receptors, Virus; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Viral Proteins; Virus Replication | 1991 |
Parallel pathways of cell cycle control during Xenopus egg activation.
Topics: Animals; Calcium; Cell Cycle; Chromatin; Diglycerides; Endocytosis; Enzyme Activation; Golgi Apparatus; Microscopy, Electron; Microscopy, Fluorescence; Ovum; Protein Kinase C; Substrate Specificity; Tetradecanoylphorbol Acetate; Xenopus | 1991 |
Protein kinase C influences rat pulmonary vascular reactivity.
Topics: Animals; Calcium; Diglycerides; Diterpenes; Endothelium, Vascular; Enzyme Activation; Hydrogen; In Vitro Techniques; Lung; Male; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Pulmonary Artery; Rats; Rats, Inbred Strains; Sodium; Terpenes; Tetradecanoylphorbol Acetate; Vasoconstriction | 1990 |
A glycerol ether induces mobilization and 12-lipoxygenation of arachidonic acid in macrophages. Synergistic effect on mobilization and induction of leukotriene C formation by activators of protein kinase C.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Diglycerides; Dinoprostone; Drug Synergism; Enzyme Activation; Glyceryl Ethers; Hydroxyeicosatetraenoic Acids; Kinetics; Macrophages; Mice; Peritoneal Cavity; Phosphoproteins; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1990 |
Involvement of a guanine-nucleotide-binding protein-mediated mechanism in the enhancement of arachidonic acid liberation by phorbol 12-myristate 13-acetate and Ca2+ in saponin-permeabilized platelets.
Topics: Alkaloids; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Cell Membrane Permeability; Chlorides; Diglycerides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Pertussis Toxin; Protein Kinase C; Rabbits; Saponins; Sodium Fluoride; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Virulence Factors, Bordetella | 1990 |
Multiple doses of diacylglycerol and calcium ionophore are necessary to activate AP-1 enhancer activity and induce markers of macrophage differentiation.
Topics: Blotting, Northern; Cell Differentiation; Diglycerides; DNA-Binding Proteins; Drug Administration Schedule; Enhancer Elements, Genetic; Humans; In Vitro Techniques; Ionomycin; Macrophages; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factors; Tumor Cells, Cultured | 1990 |
Modulation of mast cell responses to adenosine by agents that alter protein kinase C activity.
Topics: Adenosine; Animals; beta-N-Acetylhexosaminidases; Calcimycin; Cells, Cultured; Cytosol; Diglycerides; Enzyme Activation; Glycerides; Mast Cells; Mice; Mice, Inbred BALB C; Protein Kinase C; SRS-A; Tetradecanoylphorbol Acetate | 1990 |
1,2-Diacylglycerols overcome cyclic AMP-mediated inhibition of phosphatidylcholine synthesis in GH3 pituitary cells.
Topics: Bucladesine; Cell Line; Cholera Toxin; Cyclic AMP; Diglycerides; Glycerides; Phosphates; Phosphatidylcholines; Pituitary Gland; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1990 |
Sphingosine differentially inhibits activation of the Na+/H+ exchanger by phorbol esters and growth factors.
Topics: Animals; Animals, Newborn; Biological Transport; Carrier Proteins; Cells, Cultured; Detergents; Diglycerides; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Phorbol 12,13-Dibutyrate; Platelet-Derived Growth Factor; Rats; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate; Thrombin | 1990 |
Progesterone modulation of gonadotropin secretion by dispersed rat pituitary cells in culture. III. A23187, cAMP, phorbol ester and DiC8-stimulated luteinizing hormone release.
Topics: Animals; Calcimycin; Cells, Cultured; Cholera Toxin; Cyclic AMP; Diglycerides; Estradiol; Female; Luteinizing Hormone; Pituitary Gland, Anterior; Pituitary Hormone-Releasing Hormones; Progesterone; Prolactin; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Effects of Ca2+ ionophore A23187, 1,2-dioctanoylglycerol, and dibutyryl cAMP on the activity and expression of ornithine decarboxylase in guinea pig lymphocytes.
Topics: Animals; Bucladesine; Calcimycin; Cells, Cultured; Diglycerides; Glycerides; Guinea Pigs; Lymphocytes; Ornithine Decarboxylase; RNA, Messenger; Tetradecanoylphorbol Acetate | 1990 |
Physiologic 1,2-diacylglycerol levels induce protein kinase C-independent translocation of a regulatory enzyme.
Topics: Biological Transport; Cell Line; Cell Membrane; Choline; Choline-Phosphate Cytidylyltransferase; Cytosol; Diglycerides; Down-Regulation; Glycerides; Microsomes; Nucleotidyltransferases; Phosphates; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Phospholamban and troponin I are substrates for protein kinase C in vitro but not in intact beating guinea pig hearts.
Topics: Animals; Calcium; Calcium-Binding Proteins; Cyclic AMP; Cytosol; Diglycerides; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Myocardium; Myofibrils; Perfusion; Phosphates; Phosphatidylserines; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Protein Kinase C; Sarcoplasmic Reticulum; Substrate Specificity; Tetradecanoylphorbol Acetate; Troponin; Troponin I; Troponin T | 1990 |
Inhibitory effect of phorbol ester on sodium transport in frog urinary bladder.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine Vasopressin; Biological Transport; Colforsin; Cyclic AMP; Diglycerides; Rana catesbeiana; Sodium; Sphingosine; Tetradecanoylphorbol Acetate; Urinary Bladder | 1990 |
Utility of staurosporine in uncovering differences in the signal transduction pathways for superoxide production in neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Diglycerides; Guinea Pigs; In Vitro Techniques; Isoquinolines; Models, Chemical; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Peritoneal Cavity; Phosphoproteins; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Signal Transduction; Staurosporine; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate | 1990 |
In vitro modulation of porcine Leydig cell steroidogenesis by phorbol-12-myristate-13-acetate and 1,2-dioctanoylglycerol.
Topics: Animals; Cells, Cultured; Diglycerides; Drug Synergism; Glycerides; In Vitro Techniques; Leydig Cells; Luteinizing Hormone; Male; Pregnenolone; Second Messenger Systems; Swine; Testosterone; Tetradecanoylphorbol Acetate | 1990 |
Adenosine A1 receptor-mediated inhibition of surfactant secretion in rat type II pneumocytes.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Choline; Colforsin; Diglycerides; Ionomycin; Kinetics; Lung; Male; Phosphatidylcholines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Terbutaline; Tetradecanoylphorbol Acetate | 1990 |
Activation of resting human T cells requires prolonged stimulation of protein kinase C.
Topics: Cell Membrane; Cells, Cultured; Diglycerides; DNA Replication; Humans; Interleukin-2; Ionomycin; Kinetics; Lymphocyte Activation; Protein Kinase C; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine | 1990 |
Phorbol ester and dioctanoylglycerol stimulate membrane association of protein kinase C and have a negative inotropic effect mediated by changes in cytosolic Ca2+ in adult rat cardiac myocytes.
Topics: Animals; Biological Transport; Calcium; Cell Membrane; Cytosol; Diglycerides; Glycerides; Male; Myocardial Contraction; Myocardium; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1990 |
Differential effect of diacylglycerols and phorbol ester on arachidonic acid metabolism in bone marrow-derived macrophages.
Topics: Animals; Arachidonic Acids; Bone Marrow Cells; Diglycerides; Dinoprostone; Glycerides; In Vitro Techniques; Macrophages; Mice; Phospholipases A; Phospholipases A2; Tetradecanoylphorbol Acetate | 1990 |
Differential activation of protein kinase C alpha is associated with arachidonate release in Madin-Darby canine kidney cells.
Topics: Animals; Arachidonic Acids; Bradykinin; Cell Line; Diglycerides; Dogs; Enzyme Activation; Kidney; Kinetics; Phorbol 12,13-Dibutyrate; Phospholipids; Protein Kinase C; Tetradecanoylphorbol Acetate | 1990 |
Evidence for a modulatory role of protein kinase C on glycosaminoglycan biosynthesis during the spontaneous differentiation of Caco-2 cells.
Topics: Biological Transport; Cell Differentiation; Cell Membrane; Colonic Neoplasms; Cytosol; Diglycerides; Enzyme Activation; Glycosaminoglycans; Humans; Protein Kinase C; Sulfates; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1990 |
Specific inhibition of phorbol ester and DiC8-induced histamine release from human basophils by the protein kinase C inhibitors, H-7 and H-9.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Basophils; Calcimycin; Calmodulin; Diglycerides; Glycerides; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Isoquinolines; Kinetics; Perphenazine; Piperazines; Protein Kinase C; Sulfonamides; Tetradecanoylphorbol Acetate | 1987 |
Effects of activation of protein kinase C on the agonist-induced stimulation and inhibition of cyclic AMP formation in intact human platelets.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Alprostadil; Blood Platelets; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Epinephrine; Humans; Prostaglandin D2; Prostaglandins D; Protein Kinase C; Tetradecanoylphorbol Acetate | 1987 |
Modulation of human leukocyte histamine release by sn-1,2-isopropylidene-3-decanoyl-glycerol and decanoic acid cyclopentyl methylester in comparison with effects of synthetic diacylglycerols and a phorbol ester.
Topics: Calcimycin; Cyclopentanes; Decanoic Acids; Diglycerides; Glyceryl Ethers; Histamine Release; Humans; Immunoglobulin E; Leukocytes; N-Formylmethionine Leucyl-Phenylalanine; Tetradecanoylphorbol Acetate; Triglycerides | 1989 |
Activators of protein kinase C up-regulate the cell surface expression of CD2 and CD5 T cell glycoproteins.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Antibodies, Monoclonal; Antigens, Differentiation; Antigens, Differentiation, T-Lymphocyte; Calcium Channel Blockers; CD2 Antigens; CD5 Antigens; Cell Membrane; Cells, Cultured; Cycloheximide; Diglycerides; Dinoprostone; Enzyme Activation; Flow Cytometry; Humans; Isoquinolines; Membrane Glycoproteins; Phorbol 12,13-Dibutyrate; Piperazines; Protein Kinase C; Receptors, Immunologic; RNA, Messenger; Sulfonamides; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Involvement of protein kinase C in translocation of desmoplakins from cytosol to plasma membrane during desmosome formation in human squamous cell carcinoma cells grown in low to normal calcium concentration.
Topics: Calcimycin; Calcium; Carcinoma, Squamous Cell; Cell Membrane; Cytoskeletal Proteins; Cytosol; Desmoplakins; Desmosomes; Diglycerides; Dose-Response Relationship, Drug; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Evidence for an inhibitory effect of protein kinase C on G-protein-mediated repetitive calcium transients in hamster eggs.
Topics: Animals; Calcium; Cricetinae; Diglycerides; Female; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol 1,4,5-Trisphosphate; Male; Membrane Potentials; Mesocricetus; Ovum; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate; Thionucleotides | 1989 |
Protein kinase C-dependent and -independent mechanisms of cloned murine T cell proliferation. The role of protein kinase C translocation and protein kinase C activity.
Topics: Animals; Calcimycin; Clone Cells; Diglycerides; Dose-Response Relationship, Immunologic; Drug Combinations; Enzyme Activation; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Protein Kinase C; Receptors, Antigen, T-Cell; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Studies of signal transduction in the respiratory burst-associated stimulation of fMet-Leu-Phe-induced tubulin tyrosinolation and phorbol 12-myristate 13-acetate-induced posttranslational incorporation of tyrosine into multiple proteins in activated neutr
Topics: Cell Line; Diglycerides; Humans; In Vitro Techniques; Kinetics; Leukemia, Promyelocytic, Acute; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Protein Kinase C; Protein Processing, Post-Translational; Signal Transduction; Superoxides; Tetradecanoylphorbol Acetate; Tubulin; Tyrosine | 1989 |
The effects of protein kinase-C agonists on parathyroid hormone release and intracellular free Ca2+ in bovine parathyroid cells.
Topics: Animals; Bryostatins; Calcium; Cattle; Diglycerides; Glycerides; In Vitro Techniques; Intracellular Fluid; Kinetics; Lactones; Macrolides; Parathyroid Glands; Parathyroid Hormone; Phosphotransferases; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
In vitro correction of impaired Na+-K+-ATPase in diabetic nerve by protein kinase C agonists.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Diglycerides; Kinetics; Male; Ouabain; Protein Kinase C; Rabbits; Reference Values; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 1989 |
Phosphorylation of both 47 and 49kDa proteins accompanies superoxide release by neutrophils.
Topics: Animals; Diglycerides; Enzyme Activation; Guinea Pigs; Kinetics; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphates; Phosphoproteins; Phosphorylation; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Sphingosine inhibits phorbol 12-myristate 13-acetate-, but not serum-induced, activation of Na+/H+ exchange in mammalian cells.
Topics: Animals; Blood Physiological Phenomena; Carrier Proteins; Cell Line; Diglycerides; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sodium-Hydrogen Exchangers; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
Human T cell activation: differential response to anti-CD28 as compared to anti-CD3 monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Bucladesine; Calcium; CD28 Antigens; CD3 Complex; Cholera Toxin; Cyclosporins; Diglycerides; Humans; Lymphocyte Activation; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1989 |
Extracellular Na+ removal enhances granule secretion in platelets--evidence that Na+/H+ exchange is inhibitory to secretion induced by some agonists.
Topics: Blood Platelets; Calcium; Carrier Proteins; Collagen; Diglycerides; Electrophoresis, Polyacrylamide Gel; Extracellular Space; Humans; Hydrogen-Ion Concentration; Phosphorylation; Prostaglandin Endoperoxides, Synthetic; Serotonin; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate; Thrombin | 1989 |
Na+/H+ exchange is not necessary for protein kinase C-mediated effects in platelets.
Topics: Autoradiography; beta-Thromboglobulin; Blood Platelets; Carrier Proteins; Diglycerides; Enzyme Activation; Humans; Phosphorylation; Protein Kinase C; Proteins; Serotonin; Sodium; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1989 |
Transmembrane signals mediating adrenocorticotropin release from mouse anterior pituitary cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; Diglycerides; Egtazic Acid; Male; Mice; Phosphatidylinositols; Pituitary Gland, Anterior; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1989 |
1,2-dioctanoyl-sn-glycerol can stimulate neutrophils by different mechanisms. Evidence for a pathway that does not involve phosphorylation of the 47-kDa protein.
Topics: Alkaloids; Animals; Diglycerides; Diterpenes; Glycerides; Guinea Pigs; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Proteins; Staurosporine; Superoxides; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Enhancement of the invasive ability of a transformed human bronchial epithelial cell line by 12-O-tetradecanoyl-phorbol-13-acetate and diacylglycerol.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chemotaxis; Diglycerides; Epithelium; Glycerides; Humans; Lung; Mice; Mice, Nude; Microbial Collagenase; Neoplasm Invasiveness; Neoplasm Transplantation; Rats; Tetradecanoylphorbol Acetate; Trachea; Transplantation, Heterologous | 1989 |
Comparison of epidermal protein kinase C activity, ornithine decarboxylase induction and DNA synthesis stimulated by TPA or dioctanoylglycerol in mouse strains with differing susceptibility to TPA-induced tumor promotion.
Topics: Animals; Brain; Diglycerides; DNA Replication; Enzyme Induction; Female; Glycerides; Kinetics; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Skin; Species Specificity; Tetradecanoylphorbol Acetate | 1989 |
Regulation of eicosanoid synthesis in mouse peritoneal macrophages by protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acids; Diglycerides; Dinoprostone; Isoquinolines; Macrophages; Mice; Piperazines; Protein Kinase C; Sphingosine; Tetradecanoylphorbol Acetate | 1989 |
Induction of plasminogen activator activity by phorbol ester in transformed fetal bovine aortic endothelial cells. Possible independence from protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aorta; Cattle; Cell Line, Transformed; Diglycerides; Endothelium, Vascular; Enzyme Activation; Fetus; Isoquinolines; Mitogens; Piperazines; Plasminogen Activators; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Protein kinase C activity can desensitize the gonadotropin-responsive adenylate cyclase in Leydig tumor cells. But hCG-induced desensitization does not involve protein kinase C activation.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Cell Line; Chorionic Gonadotropin; Diglycerides; Enzyme Activation; Inositol; Kinetics; Leydig Cell Tumor; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Retention of specific protein kinase C isozymes following chronic phorbol ester treatment in BC3H-1 myocytes.
Topics: Animals; Cell Line; Cells, Cultured; Diglycerides; Histones; Isoenzymes; Mice; Muscles; Phosphorylation; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Time Factors | 1989 |
Synthetic lipid second messenger sn-1,2-didecanoylglycerol: a complete tumor promoter in mouse skin.
Topics: Animals; Carcinogens; Diglycerides; Diterpenes; Female; Glycerides; Mice; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1989 |
Synthetic diacylglycerols trigger an increase of intracellular free calcium in promyelocytic HL60 cells.
Topics: Benzofurans; Calcium; Cell Line; Cell Membrane Permeability; Diglycerides; Fura-2; Glycerides; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Leukemia, Promyelocytic, Acute; Potassium; Sodium; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1989 |
Comparison of phorbol-12-myristate-13-acetate and dioctanoyl-sn-glycerol in the activation of EL4/6.1 thymoma cells.
Topics: Animals; Diglycerides; Ethers; Flow Cytometry; Glycerides; Interleukin-1; Ionomycin; Lymphocyte Activation; Mice; Protein Kinase C; Receptors, Interleukin-2; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymoma; Tumor Cells, Cultured | 1989 |
Inhibition of the CD3-mediated calcium signal by protein kinase C activators in human T (Jurkat) lymphoblastoid cells.
Topics: Antigens, Differentiation, T-Lymphocyte; Calcium; Cell Line; Depression, Chemical; Diglycerides; Enzyme Activation; Glycerides; Humans; Lymphocyte Activation; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |
Loss of copper-zinc superoxide dismutase gene expression in differentiated cells of myelo-monocytic origin.
Topics: Cell Differentiation; Cell Line; Diglycerides; Gene Expression; Genes; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; RNA, Messenger; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1989 |
Antibody-induced cAMP accumulation in splenocytes from athymic nude mice.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Colforsin; Cyclic AMP; Diglycerides; DNA Replication; Enzyme Activation; Mice; Mice, Nude; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Protein Kinase C; Receptors, Antigen, B-Cell; Spleen; Tetradecanoylphorbol Acetate | 1987 |
Attenuation of pituitary polyphosphoinositide metabolism by protein kinase C activation.
Topics: Animals; Calcium; Diglycerides; Enzyme Activation; Female; Inositol Phosphates; Phosphatidylinositol Phosphates; Phosphatidylinositols; Pituitary Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1987 |
Phorbol diesters and dioctanoylglycerol stimulate accumulation of both diacylglycerols and alkylacylglycerols in human neutrophils.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Chlorpromazine; Diglycerides; Ethers; Glycerides; Glyceryl Ethers; Humans; In Vitro Techniques; Ionomycin; Isoquinolines; Kinetics; Neutrophils; Piperazines; Protein Kinase C; Sphingosine; Superoxides; Tetradecanoylphorbol Acetate | 1988 |
Phorbol myristate acetate and dioctanoylglycerol inhibit transport in rabbit proximal convoluted tubule.
Topics: Absorption; Animals; Bicarbonates; Biological Transport, Active; Diglycerides; Enzyme Activation; Glucose; Glycerides; Kidney Tubules, Proximal; Protein Kinase C; Rabbits; Sodium; Sodium Bicarbonate; Sodium Chloride; Tetradecanoylphorbol Acetate | 1988 |
Differential sensitivity of agonist- and antagonist-occupied gonadotropin-releasing hormone receptors to protein kinase C activators. A marker for receptor activation.
Topics: Animals; Buserelin; Cell Membrane; Cells, Cultured; Diglycerides; Enzyme Activation; Female; Glycerides; Gonadotropin-Releasing Hormone; Kinetics; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pituitary Gland; Protein Kinase C; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, LHRH; Tetradecanoylphorbol Acetate | 1988 |
Differential effects of the diacylglycerol kinase inhibitor R59022 on thrombin versus collagen-induced human platelet secretion.
Topics: Arachidonic Acid; Arachidonic Acids; Blood Platelets; Calcium; Collagen; Diacylglycerol Kinase; Diglycerides; Dose-Response Relationship, Drug; Ethers; Glycerides; Humans; Ionomycin; Phosphoproteins; Phosphotransferases; Platelet Aggregation; Pyrimidinones; Serotonin; Tetradecanoylphorbol Acetate; Thiazoles; Thrombin | 1988 |
1,2-Diacylglycerols, but not phorbol esters, activate a potential inhibitory pathway for protein kinase C in GH3 pituitary cells. Evidence for involvement of a sphingomyelinase.
Topics: Animals; Cell Line; Cell Membrane; Cytosol; Diglycerides; Enzyme Activation; Glycerides; Kinetics; Phosphoric Diester Hydrolases; Pituitary Neoplasms; Protein Kinase C; Sphingomyelin Phosphodiesterase; Tetradecanoylphorbol Acetate | 1988 |
Glucagon gene transcription in an islet cell line is regulated via a protein kinase C-activated pathway.
Topics: Angiotensinogen; Animals; Bucladesine; Cell Line; Diglycerides; Enzyme Activation; Glucagon; Hydrocortisone; Insulin; Islets of Langerhans; Protein Kinase C; RNA, Messenger; Somatostatin; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic | 1987 |
Activation of human T cells with the physiological regulator of protein kinase C.
Topics: Antigens, Differentiation, T-Lymphocyte; CD2 Antigens; CD3 Complex; Cell Division; Diglycerides; Egtazic Acid; Ethers; Glycerides; Humans; In Vitro Techniques; Interleukin-2; Ionomycin; Lymphocyte Activation; Protein Kinase C; Receptors, Antigen, T-Cell; Receptors, Immunologic; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Analysis of calcium homeostasis in activated human polymorphonuclear leukocytes. Evidence for two distinct mechanisms for lowering cytosolic calcium.
Topics: Alkaloids; Benzofurans; Calcium; Cytosol; Diglycerides; Ethers; Fura-2; Homeostasis; Humans; In Vitro Techniques; Ionomycin; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pertussis Toxin; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1989 |
sn-1,2-Dioctanoylglycerol. A cell-permeable diacylglycerol that mimics phorbol diester action on the epidermal growth factor receptor and mitogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Cell Line; Diglycerides; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Glycerides; Humans; Mice; Mitosis; Phorbol Esters; Phorbols; Phospholipids; Phosphoproteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Receptors, Cell Surface; Tetradecanoylphorbol Acetate | 1985 |
Involvement of protein kinase C in the regulation of adrenocorticotropin release from rat anterior pituitary cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Corticosterone; Corticotropin-Releasing Hormone; Diglycerides; Dose-Response Relationship, Drug; Feedback; Kinetics; Pituitary Gland, Anterior; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1986 |
Protein kinase C agonists acutely normalize decreased ouabain-inhibitable respiration in diabetic rabbit nerve. Implications for (Na,K)-ATPase regulation and diabetic complications.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Diglycerides; Glycerides; Inositol; Male; Ouabain; Oxygen Consumption; Peripheral Nerves; Phorbols; Protein Kinase C; Rabbits; Rats; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 1986 |
Biphasic inhibition of adrenocorticotropin release by corticosterone in cultured anterior pituitary cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Angiotensin II; Animals; Cells, Cultured; Corticosterone; Cycloheximide; Diglycerides; Dose-Response Relationship, Drug; Female; Kinetics; Norepinephrine; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Vasopressins | 1986 |
The effect of cAMP on tumour promoter responses mediated by C-kinase.
Topics: Aminophylline; Animals; Bucladesine; Carcinogens; Cell Communication; Cell Line; Cyclic AMP; Diglycerides; Epidermal Growth Factor; Glycerides; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Action of retinoic acid on the diacylglycerol-induced ornithine decarboxylase activity, reduction in EGF binding and protein kinase C activation in rat tracheal epithelial 2C5 cells.
Topics: Animals; Cell Line; Diglycerides; Enzyme Activation; Enzyme Induction; Epidermal Growth Factor; ErbB Receptors; Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; Receptors, Cell Surface; Tetradecanoylphorbol Acetate; Trachea; Tretinoin | 1986 |
The effect of phorbol esters and diacylglycerol on expression of the phosphoenolpyruvate carboxykinase (GTP) gene in rat hepatoma H4IIE cells.
Topics: Animals; Cell Line; Cyclic AMP; Cycloheximide; Dexamethasone; Diglycerides; Genes; Glycerides; Kinetics; Liver Neoplasms, Experimental; Phorbol Esters; Phosphoenolpyruvate Carboxykinase (GTP); Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1986 |
Sensitization of adrenocortical cell adenylate cyclase activity to ACTH by angiotensin II and activators of protein kinase C.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adrenal Cortex; Adrenocorticotropic Hormone; Angiotensin II; Animals; Cattle; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Pertussis Toxin; Protein Kinase C; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1987 |
sn-1,2-Diacylglycerols and phorbol diesters stimulate thromboxane synthesis by de novo synthesis of prostaglandin H synthase in human promyelocytic leukemia cells.
Topics: Arachidonic Acid; Arachidonic Acids; Calcimycin; Cell Differentiation; Cell Line; Diglycerides; Glycerides; Humans; Kinetics; Leukemia, Myeloid; Macrophages; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Tetradecanoylphorbol Acetate; Thromboxane B2; Trifluoperazine | 1987 |
Diacylglycerol induces deacylation of phosphatidylinositol and mobilization of arachidonic acid in mouse macrophages. Comparison with induction by phorbol diester.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cells, Cultured; Chlorpromazine; Diglycerides; Dose-Response Relationship, Drug; Female; Glycerides; Macrophages; Mice; Phosphatidylinositols; Phospholipids; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
Dynamic actions of arachidonic acid and protein kinase C in pituitary stimulation by gonadotropin-releasing hormone.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Diglycerides; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Masoprocol; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Retinaldehyde; Tetradecanoylphorbol Acetate | 1987 |
Diacylglycerol increases cytosolic free Ca2+ concentration in rat pituitary cells. Relationship to thyrotropin-releasing hormone action.
Topics: Animals; Calcium; Cell Line; Cytosol; Diglycerides; Glycerides; Kinetics; Pituitary Neoplasms; Rats; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1987 |
Measurement of synergistic effects of protein kinase C activators and calcium ionophore in pituitary cell cultures.
Topics: Animals; Calcimycin; Cells, Cultured; Diglycerides; Drug Synergism; Enzyme Activation; Female; Kinetics; Luteinizing Hormone; Pituitary Gland; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Disparate effects of activators of protein kinase C on HL-60 promyelocytic leukemia cell differentiation.
Topics: Calcimycin; Cell Differentiation; Cell Line; Diglycerides; Diterpenes; Enzyme Activation; Humans; Leukemia, Myeloid, Acute; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate | 1987 |
Human immunodeficiency virus (HIV-1) cytotoxicity: perturbation of the cell membrane and depression of phospholipid synthesis.
Topics: Calcium; Cell Division; Cell Line; Cell Membrane; Cell Membrane Permeability; Cell Survival; Cytopathogenic Effect, Viral; Diglycerides; HIV; HIV Core Protein p24; Humans; Lipids; Phospholipids; Retroviridae Proteins; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1988 |
Mechanism of thrombin-induced rise in platelet fructose 2,6-bisphosphate content. Studies using phorbol myristate acetate, dioctanoylglycerol and ionophore A23187.
Topics: Blood Platelets; Calcimycin; Calcium; Diglycerides; Egtazic Acid; Fructosediphosphates; Glycolysis; Hexosediphosphates; Humans; Indomethacin; Tetradecanoylphorbol Acetate; Thrombin | 1987 |
Dependence of secretory responses to gonadotropin-releasing hormone on diacylglycerol metabolism. Studies with a diacylglycerol lipase inhibitor, RHC 80267.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclohexanes; Cyclohexanones; Diglycerides; Ethers; Female; Follicle Stimulating Hormone; Glycerides; Gonadotropin-Releasing Hormone; Ionomycin; Lipoprotein Lipase; Luteinizing Hormone; Pituitary Gland, Anterior; Rats; Tetradecanoylphorbol Acetate | 1988 |
In vivo effects of Sn-1,2-dioctanoylglycerol, TPA and A23187 on hamster cheek pouch epithelium.
Topics: Animals; Calcimycin; Cell Division; Cheek; Connective Tissue; Connective Tissue Cells; Cricetinae; Diglycerides; Epithelial Cells; Epithelium; Fluocinolone Acetonide; Glycerides; Hyperplasia; Male; Mesocricetus; Mitosis; Mouth Mucosa; Tetradecanoylphorbol Acetate | 1988 |
Decline in c-myc mRNA expression but not the induction of c-fos mRNA expression is associated with differentiation of SH-SY5Y human neuroblastoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Differentiation; Cell Line; Diglycerides; Gene Expression Regulation; Humans; Isoquinolines; Neuroblastoma; Oncogenes; Piperazines; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1988 |
Protein kinase C and membrane transport: divergent responses of Na+/K+/Cl- cotransport and sugar transport to exogenous diacylglycerol.
Topics: Animals; Carrier Proteins; Cell Membrane; Cells, Cultured; Chlorides; Diglycerides; Glycerides; Kinetics; Mice; Mice, Inbred BALB C; Monosaccharide Transport Proteins; Ornithine Decarboxylase; Potassium; Protein Kinase C; Rubidium; Sodium; Sodium-Potassium-Chloride Symporters; Tetradecanoylphorbol Acetate | 1988 |
Inhibition of MCF-7 cell growth by 12-O-tetradecanoylphorbol-13-acetate and 1,2-dioctanoyl-sn-glycerol: distinct effects on protein kinase C activity.
Topics: Breast Neoplasms; Cell Division; Diglycerides; Dose-Response Relationship, Drug; Female; Glycerides; Humans; Phosphorylation; Protein Kinase C; Proteins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Stereospecific bioactions of 5-hydroxyeicosatetraenoate.
Topics: Calcium; Diglycerides; Exocytosis; Glucuronidase; Humans; Hydroxyeicosatetraenoic Acids; Muramidase; Neutrophils; Platelet Activating Factor; Stereoisomerism; Tetradecanoylphorbol Acetate | 1988 |
Activators of protein kinase C and phenylephrine depolarize the astrocyte membrane by reducing the K+ permeability.
Topics: Animals; Astrocytes; Cells, Cultured; Diglycerides; Dithiazanine; Phenylephrine; Potassium; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1988 |
Effect of tumor promoter 12-O-tetradecanoyl-phorbol 13-acetate on CD 7 expression by T lineage cells.
Topics: Antibodies, Monoclonal; Antigens, Differentiation, T-Lymphocyte; Depression, Chemical; Diglycerides; Ethers; Gene Expression Regulation; Humans; Ionomycin; Leukemia; Phosphatidylinositols; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Independent transcriptional regulation of a single VL30 element by epidermal growth factor and activators of protein kinase C.
Topics: Animals; Cell Line; Diglycerides; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation; Glycerides; Mice; Multigene Family; Protein Kinase C; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Transcription, Genetic | 1988 |
Insulin and phorbol ester stimulate conductive Na+ transport through a common pathway.
Topics: Animals; Diglycerides; Drug Interactions; Enzyme Activation; Insulin; Protein Kinase C; Rana pipiens; Skin; Sodium; Sphingosine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Vasopressins | 1988 |
Stimulation by phorbol ester and diacylglycerol of luteinizing hormone glycosylation and release by rat anterior pituitary cells.
Topics: Animals; Cells, Cultured; Diglycerides; Estradiol; Female; Glycerides; Glycosylation; Gonadotropin-Releasing Hormone; Kinetics; Luteinizing Hormone; Ovariectomy; Pituitary Gland, Anterior; Protein Processing, Post-Translational; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
1,2-Dioctanoyl-glycerol induces a discrete but transient translocation of protein kinase C as well as the inhibition of MCF-7 cell proliferation.
Topics: Breast Neoplasms; Cell Division; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Female; Glycerides; Humans; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
A role for protein kinase C in astrocyte glycogen metabolism.
Topics: Animals; Astrocytes; Cells, Cultured; Cerebral Cortex; Colforsin; Deoxyglucose; Diglycerides; Glycogen; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1988 |
Dioctanoylglycerol and phorbol esters regulate transcription of c-myc in human promyelocytic leukemia cells.
Topics: Diglycerides; Enzyme Activation; Glycerides; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Proto-Oncogenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1988 |
Mimicry of phorbol ester responses by diacylglycerols. Differential effects on phosphatidylcholine biosynthesis, cell-cell communication and epidermal growth factor binding.
Topics: Animals; Cell Communication; Cell Line; Diglycerides; Epidermal Growth Factor; Epidermis; Glycerides; Intercellular Junctions; Mice; Phorbols; Phosphatidylcholines; Protein Kinase C; Tetradecanoylphorbol Acetate | 1986 |
Diacylglycerols stimulate short-circuit current across frog skin by increasing apical Na+ permeability.
Topics: Animals; Diglycerides; Electric Conductivity; Epithelium; Glycerides; Kinetics; Membrane Potentials; Models, Biological; Permeability; Rana pipiens; Skin; Skin Physiological Phenomena; Sodium; Tetradecanoylphorbol Acetate | 1987 |
Calcium transients in human platelets monitored by aequorin, fura-2 and quin-2: effects of protein kinase C activation and inhibition.
Topics: Aequorin; Alkaloids; Aminoquinolines; Benzofurans; Blood Platelets; Calcium; Diglycerides; Enzyme Activation; Fluorescent Dyes; Fura-2; Humans; Kinetics; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1987 |
1,2-Diacylglycerols and phorbol esters stimulate phosphatidylcholine metabolism in GH3 pituitary cells. Evidence for separate mechanisms of action.
Topics: Animals; Cytidine Diphosphate Choline; Diglycerides; Glycerides; Phorbol Esters; Phosphatidylcholines; Pituitary Neoplasms; Rats; Stearic Acids; Tetradecanoylphorbol Acetate | 1987 |
Synthetic diacylglycerols induce a rise of quin2-detectable free intracellular calcium in human platelets.
Topics: Aminoquinolines; Blood Platelets; Calcium; Colforsin; Diglycerides; Enzyme Activation; Fluorescent Dyes; Glycerides; Humans; Protein Kinase C; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1987 |
1,2-Dioctanoylglycerol but not 1-oleoyl-2-acetylglycerol inhibits agonist-induced platelet responses. Dependence of effects on extent of 45-kDa protein phosphorylation and agonist type.
Topics: Blood Platelets; Blood Proteins; Calcium; Collagen; Diglycerides; Ethers; Glycerides; Humans; Ionomycin; Kinetics; Male; Molecular Weight; Phosphorylation; Tetradecanoylphorbol Acetate; Thrombin; Thromboxane B2 | 1987 |
Effects of protein kinase C activation on sodium, potassium, chloride, and total CO2 transport in the rabbit cortical collecting tubule.
Topics: Animals; Bicarbonates; Biological Transport; Chlorides; Diglycerides; Enzyme Activation; Female; Kidney Tubules; Kidney Tubules, Collecting; Potassium; Protein Kinase C; Rabbits; Sodium; Tetradecanoylphorbol Acetate | 1987 |
Differential regulation of phosphatidylcholine biosynthesis by 12-O-tetradecanoylphorbol-13-acetate and diacylglycerol in NG108-15 neuroblastoma x glioma hybrid cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Choline; Chromatography, High Pressure Liquid; Diglycerides; Glioma; Glycerides; Hybrid Cells; Isoquinolines; Neuroblastoma; Phosphatidylcholines; Piperazines; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1987 |
Sn-1,2-diacylglycerols and phorbol esters stimulate the synthesis and release of human placental lactogen from placental cells: a role for protein kinase C.
Topics: Cycloheximide; Diglycerides; Dose-Response Relationship, Drug; Glycerides; Humans; Methionine; Phorbol Esters; Placenta; Placental Lactogen; Protein Kinase C; Tetradecanoylphorbol Acetate; Trophoblasts | 1986 |
Effects of mitogens on ornithine decarboxylase activity and messenger RNA levels in normal and protein kinase C-deficient NIH-3T3 fibroblasts.
Topics: Animals; Cell Line; Diglycerides; Enzyme Induction; Fetal Blood; Fibroblast Growth Factors; Fibroblasts; Kinetics; Mice; Mitogens; Ornithine Decarboxylase; Platelet-Derived Growth Factor; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate | 1986 |
Effects of phorbol esters and a diacylglycerol on mouse eggs: inhibition of fertilization and modification of the zona pellucida.
Topics: Acrosome; Animals; Diglycerides; Female; Fertilization; Glycerides; Kinetics; Male; Mice; Ovum; Phorbol Esters; Rats; Rats, Inbred Strains; Sperm-Ovum Interactions; Tetradecanoylphorbol Acetate; Zona Pellucida | 1987 |
Angiotensin II inhibits cytokine-stimulated inducible nitric oxide synthase expression in vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Diglycerides; Enzyme Induction; Humans; Imidazoles; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Pyridines; Rats; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetrazoles; Tumor Necrosis Factor-alpha | 1994 |
Protein kinase C modulates receptor-independent activation of endothelial nitric oxide synthase.
Topics: Alkaloids; Amino Acid Oxidoreductases; Animals; Cattle; Cells, Cultured; Diglycerides; Endothelium, Vascular; Enzyme Activation; Nitric Oxide Synthase; Protein Kinase C; Pulmonary Artery; Staurosporine; Tetradecanoylphorbol Acetate | 1994 |
Translocation of protein kinase C isozymes in lactotroph-enriched rat anterior pituitary cell cultures: differential effects of substance P and phorbol ester.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Arachidonic Acid; Biological Transport; Calcium; Diglycerides; Enzyme Activation; Isoenzymes; Male; Molecular Sequence Data; Phosphatidylinositol Diacylglycerol-Lyase; Phospholipases A; Phosphoric Diester Hydrolases; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Substance P; Tetradecanoylphorbol Acetate | 1994 |
Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells.
Topics: Alkaloids; Arachidonate 12-Lipoxygenase; Carcinoma, Squamous Cell; Diglycerides; Enzyme Induction; Epidermal Growth Factor; Humans; Naphthalenes; Phosphatidylinositol Phosphates; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Sphingosine derivatives inhibit depolarization-evoked calcium entry in rat GH4C1 cells.
Topics: Animals; Barium; Calcium; Calcium Channels; Calcium Radioisotopes; Cell Line; Diglycerides; Electric Conductivity; Electrophysiology; Fura-2; Lysophospholipids; Patch-Clamp Techniques; Pituitary Gland; Potassium; Rats; Sphingosine; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1995 |
The effects of N-(5-vinyl-1,3-thiazolidin-2-ylidene)phenylamine (5-VTPA) on the changes in free intracellular calcium and the production of reactive oxygen metabolites in human leukocytes.
Topics: Calcium; Cell Membrane; Centrifugation, Density Gradient; Diglycerides; Dose-Response Relationship, Drug; Drug Synergism; Humans; Leukocytes; Luminescent Measurements; N-Formylmethionine Leucyl-Phenylalanine; Protein Kinase C; Reactive Oxygen Species; Respiratory Burst; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidines | 1995 |
Effect of protein kinase C stimulators on zona pellucida binding and the acrosome reaction of macaque sperm.
Topics: Acrosome; Animals; Bucladesine; Caffeine; Calcium; Diglycerides; Enzyme Activation; Female; Macaca fascicularis; Male; Protein Kinase C; Sperm Motility; Spermatozoa; Tetradecanoylphorbol Acetate; Zona Pellucida | 1995 |
Phorbol ester-induced priming of superoxide generation by phosphatidic acid-stimulated neutrophils and granule-free neutrophil cytoplasts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Cell Survival; Cell-Free System; Cytoplasmic Granules; Diglycerides; Dose-Response Relationship, Drug; Humans; Isoquinolines; Kinetics; Naphthalenes; Neutrophils; Phosphatidic Acids; Piperazines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate | 1995 |
Differential effect of activators of protein kinase C on cytoskeletal changes in mouse and hamster eggs.
Topics: Amino Acid Sequence; Animals; Calcimycin; Cricetinae; Cytoskeleton; Diglycerides; Enzyme Activation; Female; Mesocricetus; Mice; Molecular Sequence Data; Ovum; Peptides; Phorbol Esters; Protamine Kinase; Protein Kinase C; Species Specificity; Substrate Specificity; Tetradecanoylphorbol Acetate | 1995 |
Purification and partial characterization of acrosome reaction inhibiting glycoprotein from human seminal plasma.
Topics: Acrosome; Amidohydrolases; Atrial Natriuretic Factor; Calcimycin; Calcium; Carbohydrate Conformation; Carbohydrates; Diglycerides; Electrophoresis, Polyacrylamide Gel; Exocytosis; Glycoproteins; Glycosylation; Humans; Hydrogen-Ion Concentration; Male; Molecular Weight; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Semen; Spermatozoa; Tetradecanoylphorbol Acetate | 1995 |
Activation of protein kinase C enhances the phosphorylation of the type B interleukin-8 receptor and stimulates its degradation in non-hematopoietic cells.
Topics: Alkaloids; Cell Line; Chemokine CXCL1; Chemokines, CXC; Chemotactic Factors; Diglycerides; Down-Regulation; Enzyme Activation; Growth Substances; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Pertussis Toxin; Phosphorylation; Phosphoserine; Placenta; Protein Kinase C; Receptors, Interleukin; Receptors, Interleukin-8A; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transfection; Virulence Factors, Bordetella | 1995 |
Activation of protein kinase C in rat basophilic leukemia cells stimulates increased production of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: correlation with actin polymerization.
Topics: Actins; Alkaloids; Animals; Biopolymers; Diglycerides; Dinitrophenols; Enzyme Activation; Immunologic Capping; Leukemia, Basophilic, Acute; Neoplasm Proteins; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Protein Kinase C; Rats; Receptors, IgE; Serum Albumin, Bovine; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1995 |
Transcriptional regulation of the lactate dehydrogenase A subunit gene by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Base Sequence; Diglycerides; DNA; Genes, Regulator; Glioma; Indoles; L-Lactate Dehydrogenase; Maleimides; Molecular Sequence Data; Promoter Regions, Genetic; Protein Kinase C; Rats; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Inhibition of low threshold calcium channels by angiotensin II in adrenal glomerulosa cells through activation of protein kinase C.
Topics: Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cattle; Cells, Cultured; Cytosol; Diglycerides; Drug Interactions; Enzyme Activation; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Potassium; Protein Kinase C; Tetradecanoylphorbol Acetate; Zona Glomerulosa | 1995 |
Involvement of protein kinase C in 1,25(OH)2-vitamin D3 regulation of calcium uptake by cultured myocytes.
Topics: Animals; Calcitriol; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Chick Embryo; Cyclic AMP-Dependent Protein Kinases; Cytosol; Diglycerides; Heart; Myocardium; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Involvement of protein kinase C and arachidonate signaling pathways in the alteration of proliferative response of senescent IMR-90 human fibroblasts.
Topics: Arachidonic Acid; Cell Division; Cell Line; Cellular Senescence; Diglycerides; DNA; Enzyme Activation; Fibroblasts; Humans; Indomethacin; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Thymidine | 1994 |
Effects of second messengers on the permeability and morphology of eel rete capillaries.
Topics: Albumins; Animals; Bucladesine; Calcimycin; Calcium; Capillaries; Capillary Permeability; Colforsin; Diglycerides; Eels; Isoproterenol; Microscopy, Electron; Nucleotides, Cyclic; Phosphatidylinositols; Second Messenger Systems; Sodium; Sucrose; Tetradecanoylphorbol Acetate | 1995 |
1,3-Dioctanoylglycerol (1,3-DiC8) is as effective as 1,2-dioctanoylglycerol (1,2-DiC8) in priming phospholipase A2 activation in human platelets and neutrophils.
Topics: Arachidonic Acid; Blood Platelets; Calcimycin; Diglycerides; Enzyme Activation; Humans; Neutrophils; Phospholipases A; Phospholipases A1; Phospholipases A2; Protein Kinase C; Tetradecanoylphorbol Acetate | 1994 |
Inhibition of calcium-dependent protein kinase C by hexadecylphosphocholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine do not correlate with inhibition of proliferation of HL60 and K562 cell lines.
Topics: Antineoplastic Agents; Cell Division; Cell Membrane; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Humans; Leukemia; Phospholipid Ethers; Phosphorylcholine; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Regulation of phospholipase A2 in human leukemia cell lines: its implication for intracellular signaling.
Topics: Calcium; Cell Line; Cell Membrane Permeability; Diglycerides; Electroporation; Fatty Acids, Nonesterified; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Homeostasis; Humans; Hydrogen-Ion Concentration; Isoflavones; Kinetics; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Signal Transduction; Sodium Fluoride; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured; Vanadates | 1994 |
Bidirectional modulation of parathyroid hormone-responsive adenylyl cyclase by protein kinase C.
Topics: Adenylyl Cyclases; Animals; Diglycerides; Enzyme Activation; Parathyroid Hormone; Protein Kinase C; Rats; Receptors, Parathyroid Hormone; Tetradecanoylphorbol Acetate; Time Factors | 1994 |
Two-step mechanism for actin polymerization in human erythroleukemia cells induced by phorbol ester.
Topics: Actins; Biopolymers; Cell Adhesion; Diglycerides; Enzyme Activation; Humans; Leukemia, Erythroblastic, Acute; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Inhibition of protein kinase C of human neutrophils by phosphatidylcholines.
Topics: Analysis of Variance; Calcium; Cytosol; Diglycerides; Humans; In Vitro Techniques; Neutrophils; Phosphatidylcholines; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1994 |
Growth of melanocytic cells is associated with down-regulation of protein kinase C alpha, delta, and epsilon isoforms. Possible role of diacylglycerol.
Topics: Animals; Cell Division; Cells, Cultured; Diglycerides; DNA; Down-Regulation; Isoenzymes; Melanocytes; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate | 1993 |
Studies on the metabolism of metallothionein and alkaline phosphatase of adult rat primary hepatocyte cultures: role of fetal calf serum and agonists of the phosphoinositide cascade.
Topics: Alkaline Phosphatase; Angiotensin II; Animals; Arginine Vasopressin; Calcimycin; Cells, Cultured; Culture Media; Dexamethasone; Diglycerides; Liver; Metallothionein; Phosphatidylinositols; Platelet Activating Factor; Rats; Tetradecanoylphorbol Acetate; Zinc | 1993 |
Activation of actin polymerization by phosphatidic acid derived from phosphatidylcholine in IIC9 fibroblasts.
Topics: Actins; Animals; Bacillus cereus; Cell Line; Cricetinae; Cricetulus; Diglycerides; Embryo, Mammalian; Fibroblasts; Kinetics; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Platelet-Derived Growth Factor; Protein Kinase C; Streptomyces; Tetradecanoylphorbol Acetate; Thrombin; Type C Phospholipases | 1993 |
Regulation of prolactin receptor expression by the tumour promoting phorbol ester 12-O-tetradecanoylphorbol-13-acetate in human breast cancer cells.
Topics: Breast Neoplasms; Carcinogens; Cycloheximide; Diglycerides; Diterpenes; Female; Gene Expression Regulation, Neoplastic; Half-Life; Humans; Protein Kinase C; Receptors, Prolactin; RNA, Messenger; RNA, Neoplasm; Terpenes; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured | 1993 |
Protein kinase C-mediated inhibition of cyclin A expression in human vascular endothelial cells.
Topics: Blotting, Western; Cell Nucleus; Cells, Cultured; Cyclins; Diglycerides; DNA Replication; Endothelium, Vascular; Fibroblast Growth Factor 2; Gene Expression; Humans; Kinetics; Protein Kinase C; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Umbilical Veins | 1993 |
Protein kinase C inhibits arginine vasopressin-stimulated cAMP accumulation via a Gi-dependent mechanism.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Arginine Vasopressin; Colforsin; Cyclic AMP; Diglycerides; Enzyme Activation; Epidermal Growth Factor; GTP-Binding Proteins; Kidney Tubules, Collecting; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate | 1993 |
Effect of protein kinase-C depletion on inositol trisphosphate-mediated and cyclic adenosine 3',5'-monophosphate-dependent protein kinase-mediated adrenocorticotropin secretion.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Cyclic AMP; Cycloheximide; Diglycerides; Inositol 1,4,5-Trisphosphate; Ionomycin; Male; Perfusion; Phorbol 12,13-Dibutyrate; Pituitary Gland, Anterior; Potassium Chloride; Protein Kinase C; Protein Kinases; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 1993 |
Role of protein kinase-C in the alpha 1-adrenoceptor-mediated responses of perfused rat liver.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Biological Transport; Cell Membrane; Cytosol; Diglycerides; Enzyme Activation; Isoquinolines; Kinetics; Liver; Male; Perfusion; Piperazines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Staurosporine; Tetradecanoylphorbol Acetate | 1993 |
Activation of phospholipase D in rat type II pneumocytes by ATP and other surfactant secretagogues.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Glycerophospholipids; Lung; Male; Osmolar Concentration; Phosphatidic Acids; Phospholipase D; Phospholipids; Protein Kinase C; Pulmonary Surfactants; Rats; Tetradecanoylphorbol Acetate | 1993 |
Protein kinase C, a pivotal regulator of hamster egg activation, functions after elevation of intracellular free calcium.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Cricetinae; Diglycerides; Egtazic Acid; Enzyme Activation; Female; Kinetics; Mesocricetus; Ovum; Phorbol Esters; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Differential translocation of protein kinase C isozymes by thrombin and platelet-derived growth factor. A possible function for phosphatidylcholine-derived diacylglycerol.
Topics: Animals; Biological Transport; Calcium; Cell Line; Cell Membrane; Chelating Agents; Choline; Cricetinae; Cricetulus; Cytosol; Diglycerides; Egtazic Acid; Inositol Phosphates; Ionomycin; Isoenzymes; Kinetics; Phosphatidylcholines; Phosphorylcholine; Platelet-Derived Growth Factor; Protein Kinase C; Tetradecanoylphorbol Acetate; Thrombin | 1993 |
Interactions of cis-fatty acids and their anilides with formyl-methionyl-leucyl-phenylalanine, phorbol myristate acetate and dioctanoyl-s,n-glycerol in human leukocytes.
Topics: Analysis of Variance; Anilides; Calcium; Diglycerides; Fatty Acids, Monounsaturated; Humans; Linoleic Acid; Linoleic Acids; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oleic Acid; Oleic Acids; Plant Oils; Rapeseed Oil; Reactive Oxygen Species; Respiratory Burst; Stereoisomerism; Tetradecanoylphorbol Acetate | 1995 |
PKC activators stimulate H+ conductance in chicken enterocytes.
Topics: Animals; Chickens; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Epithelial Cells; Hydrogen; Hydrogen-Ion Concentration; Intestines; Ion Channels; Protein Kinase C; Protons; Tetradecanoylphorbol Acetate; Zinc | 1996 |
Reversible Ca2+-dependent translocation of protein kinase C and glucose-induced insulin release.
Topics: Animals; Biological Transport; Calcium; Cell Compartmentation; Cell Line, Transformed; Cell Membrane; Cytosol; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Periodicity; Protein Binding; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1996 |
Protein kinase C activators decrease dopamine uptake into striatal synaptosomes.
Topics: Animals; Corpus Striatum; Diglycerides; Dopamine; Dose-Response Relationship, Drug; Kinetics; Male; Mice; Mice, Inbred Strains; Protein Kinase C; Synaptosomes; Tetradecanoylphorbol Acetate | 1996 |
1,2-Dioctanoyl-sn-glycerol depresses cardiac L-type Ca2+ current: independent of protein kinase C activation.
Topics: Animals; Barium; Calcium; Cells, Cultured; Diglycerides; Electric Conductivity; Enzyme Activation; Homeostasis; Kinetics; Male; Myocardium; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Ventricular Function | 1996 |
Interactions between signaling pathways in mediating GnRH-stimulated GTH release from goldfish pituitary cells: protein kinase C, but not cyclic AMP is an important mediator of GnRH-stimulated gonadotropin secretion in goldfish.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Arachidonic Acid; Calcium Channel Agonists; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Goldfish; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Male; Microspheres; Naphthalenes; Pituitary Gland; Potassium; Protein Kinase C; Salmon; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 1996 |
Phosphatidylcholine cycle: an intracellular signaling mechanism in the primordial human placenta.
Topics: Diglycerides; Female; Glycerophospholipids; Humans; In Vitro Techniques; Kinetics; Myristic Acid; Myristic Acids; Phosphates; Phosphatidic Acids; Phosphatidylcholines; Phospholipids; Phosphorus Radioisotopes; Placenta; Pregnancy; Signal Transduction; Tetradecanoylphorbol Acetate; Tritium | 1996 |
Induction of oligodendrocyte apoptosis by C2-ceramide.
Topics: Animals; Apoptosis; Brain; Cattle; Cells, Cultured; Diglycerides; DNA Fragmentation; Kinetics; Microscopy, Electron; Oligodendroglia; Phospholipases A; Sphingomyelin Phosphodiesterase; Sphingosine; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Protein kinase C induced calcium influx and sustained enhancement of ciliary beating by extracellular ATP.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Calcium; Calcium Channel Blockers; Cilia; Culture Techniques; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Esophagus; Potassium Channels; Protein Kinase C; Ranidae; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation.
Topics: Actin Depolymerizing Factors; Actins; Amino Acid Sequence; Animals; Calcimycin; Cell Membrane; Diglycerides; Diterpenes; Guinea Pigs; Humans; Hydrogen Peroxide; Immunoblotting; Marine Toxins; Microfilament Proteins; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; Okadaic Acid; Oxazoles; Oxides; Phosphorylation; Staurosporine; Terpenes; Tetradecanoylphorbol Acetate | 1997 |
Na(+)-K(+)-ATPase in frog esophagus mucociliary cell membranes: inhibition by protein kinase C activation.
Topics: 4-Nitrophenylphosphatase; Animals; Cell Membrane; Diglycerides; Enzyme Activation; Esophagus; In Vitro Techniques; Kinetics; Mucous Membrane; Ouabain; Protein Kinase C; Rana ridibunda; Sodium-Potassium-Exchanging ATPase; Tetradecanoylphorbol Acetate | 1997 |
Activators of protein kinase C decrease Ca2+ spark frequency in smooth muscle cells from cerebral arteries.
Topics: Animals; Basilar Artery; Calcium; Calcium Channels; Diglycerides; Enzyme Activation; In Vitro Techniques; Kinetics; Models, Biological; Muscle, Smooth, Vascular; Protein Kinases; Rats; Ryanodine; Tetradecanoylphorbol Acetate | 1997 |
Activation of protein kinase C triggers its ubiquitination and degradation.
Topics: Animals; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diglycerides; Down-Regulation; Enzyme Activation; Gene Expression; Genes, src; Isoenzymes; Leupeptins; Multienzyme Complexes; Proteasome Endopeptidase Complex; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Ubiquitins | 1998 |
Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells.
Topics: Animals; Arachidonic Acid; Cell Membrane; Cloning, Molecular; Cytosol; Diffusion; Diglycerides; Green Fluorescent Proteins; Isoenzymes; Luminescent Proteins; Nuclear Envelope; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein Kinase C; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, IgE; Recombinant Fusion Proteins; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured | 1998 |
Modulation of K+ channels by arachidonic acid in T84 cells. I. Inhibition of the Ca(2+)-dependent K+ channel.
Topics: Arachidonic Acid; Arachidonic Acids; Calcium; Carbachol; Cell Line; Cell Membrane; Colon; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Humans; Indomethacin; Inositol Phosphates; Intestinal Mucosa; Large-Conductance Calcium-Activated Potassium Channels; Masoprocol; Membrane Potentials; Patch-Clamp Techniques; Phospholipases A; Phospholipases A2; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Kinase C; Tetradecanoylphorbol Acetate | 1998 |
Activation and inhibition of protein kinase C protect rat neuronal cultures against ischemia-reperfusion insult.
Topics: Alkaloids; Animals; Benzophenanthridines; Cells, Cultured; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Ischemia; L-Lactate Dehydrogenase; Naphthalenes; Neurons; Phenanthridines; Protein Kinase C; Rats; Reperfusion Injury; Tetradecanoylphorbol Acetate; Time Factors | 1997 |
1,25(OH)2-vitamin D3 affects the subcellular distribution of protein kinase C isoenzymes in muscle cells.
Topics: Animals; Biological Transport; Calcitriol; Cells, Cultured; Chick Embryo; Diglycerides; DNA; Isoenzymes; Muscles; Protein Kinase C; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors | 1998 |
Intracellular calcium requirements for beta1 integrin activation.
Topics: Antibodies, Monoclonal; Calcium; Cell Adhesion; Chelating Agents; Diglycerides; Enzyme Activation; Epitopes; Fibronectins; HL-60 Cells; Humans; Integrin beta1; Ionomycin; Ionophores; Peptides; Protein Binding; Protein Kinase C; Tetradecanoylphorbol Acetate; Up-Regulation | 1998 |
Activity-dependent regulation of [Ca2+]i in avian cochlear nucleus neurons: roles of protein kinases A and C and relation to cell death.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Apoptosis; Autonomic Denervation; Brain Stem; Calcium; Chick Embryo; Cochlear Nucleus; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diglycerides; Enzyme Activation; Estrenes; Homeostasis; Indoles; Ion Transport; Maleimides; Nerve Tissue Proteins; Protein Kinase C; Pyrrolidinones; Receptors, Metabotropic Glutamate; Second Messenger Systems; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides | 1998 |
Inhibitory effect of calcium-binding protein regucalcin on protein kinase C activity in rat renal cortex cytosol.
Topics: Animals; Calcium-Binding Proteins; Carboxylic Ester Hydrolases; Cytosol; Diglycerides; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Kidney Cortex; Male; Phosphatidylserines; Protein Kinase C; Rats; Rats, Wistar; Sulfotransferases; Tetradecanoylphorbol Acetate | 1998 |
Phorbol ester stimulation of phosphatidylcholine synthesis requires expression of both protein kinase C-alpha and phospholipase D.
Topics: 3T3 Cells; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Choline; Choline Kinase; Diglycerides; Enzyme Activation; Female; Humans; Isoenzymes; Mice; Phosphatidylcholines; Protein Kinase C; Protein Kinase C-alpha; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Type C Phospholipases | 1998 |
Biotin uptake by human colonic epithelial NCM460 cells: a carrier-mediated process shared with pantothenic acid.
Topics: Alkaloids; Benzophenanthridines; Biological Transport; Biotin; Cell Line; Colon; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Humans; Intestinal Absorption; Intestinal Mucosa; Kinetics; Pantothenic Acid; Phenanthridines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate | 1998 |
PKC role in mechanically induced Ca2+ waves and ATP-induced Ca2+ oscillations in airway epithelial cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbazoles; Cell Membrane; Cells, Cultured; Diglycerides; Electric Stimulation; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Indoles; Kinetics; Maleimides; Oscillometry; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Trachea | 1999 |
Phorbol 12-myristate 13-acetate induced cell death of porcine peripheral blood polymorphonuclear leucocytes.
Topics: Animals; Apoptosis; Cell Survival; Diglycerides; DNA Fragmentation; Hydrogen Peroxide; NADPH Oxidases; Neutrophils; Superoxides; Swine; Tetradecanoylphorbol Acetate | 1998 |
Phospholipase D-derived phosphatidic acid is involved in the activation of the CD11b/CD18 integrin in human eosinophils.
Topics: Calcium; CD18 Antigens; Cell Adhesion; Cell Survival; Diglycerides; Enzyme Activation; Eosinophils; Ethanol; Fibronectins; Humans; Macrophage-1 Antigen; Phosphatidic Acids; Phospholipase D; Platelet Activating Factor; Propranolol; Protein Binding; Respiratory Burst; Tetradecanoylphorbol Acetate; Up-Regulation; Zymosan | 1999 |
Inhibition of Ca2+ influx by pentoxifylline in NR8383 alveolar macrophages.
Topics: Animals; Calcium Channels; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Diglycerides; Enzyme Activation; Flavonoids; Humans; Macrophages, Alveolar; Pentoxifylline; Phosphodiesterase Inhibitors; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Zymosan | 1999 |
Surfactant secretagogue activation of protein kinase C isoforms in cultured rat type II cells.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Diglycerides; Enzyme Activation; Isoenzymes; Lung; Male; Protein Kinase C; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Uridine Triphosphate | 1999 |
Inhibition of initial transport rate of basolateral organic anion carrier in renal PT by BK and phenylephrine.
Topics: Adrenergic alpha-Agonists; Animals; Anion Transport Proteins; Biological Transport; Bradykinin; Carrier Proteins; Diglycerides; Enzyme Inhibitors; Indoles; Intracellular Membranes; Ketoglutaric Acids; Kidney Tubules, Proximal; Male; Maleimides; Phenylephrine; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate | 1999 |
Protein kinase C (PKC) isoforms translocate to Triton-insoluble fractions in stimulated human neutrophils: correlation of conventional PKC with activation of NADPH oxidase.
Topics: Adult; Biological Transport; Cell Fractionation; Cell Membrane; Cytosol; Diglycerides; Dose-Response Relationship, Immunologic; Enzyme Activation; Humans; Isoenzymes; NADPH Oxidases; Neutrophil Activation; Neutrophils; Octoxynol; Phospholipids; Phosphoproteins; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; Proteins; Solubility; Tetradecanoylphorbol Acetate; Time Factors | 1999 |
Effects of volatile anesthetics on the direct and indirect protein kinase C-mediated enhancement of alpha1E-type Ca(2+) current in Xenopus oocytes.
Topics: Anesthetics, Inhalation; Animals; Calcium Channels; Diglycerides; Enzyme Activation; Enzyme Activators; Female; Halothane; Isoenzymes; Isoflurane; Membrane Potentials; Methacholine Chloride; Muscarinic Agonists; Oocytes; Patch-Clamp Techniques; Protein Kinase C; Receptor, Muscarinic M1; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Xenopus laevis | 2000 |
Endothelin-1 and photoreleased diacylglycerol increase L-type Ca2+ current by activation of protein kinase C in rat ventricular myocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carcinogens; Diglycerides; Electrophysiology; Endothelin-1; Enzyme Inhibitors; Male; Membrane Potentials; Muscle Fibers, Skeletal; Myocardium; Nifedipine; Phenanthridines; Photochemistry; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Ultraviolet Rays | 2000 |
Role of protein kinases in the prolactin-induced intracellular calcium rise in Chinese hamster ovary cells expressing the prolactin receptor.
Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; CHO Cells; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Prolactin; Protein Kinases; Protein-Tyrosine Kinases; Rabbits; Receptors, Prolactin; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection | 2000 |
EGF inhibits muscarinic receptor-mediated calcium signaling in a human salivary cell line.
Topics: Binding, Competitive; Calcium; Calcium Signaling; Carbachol; Cell Line; Diglycerides; Down-Regulation; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Space; Humans; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscarinic Agonists; Muscarinic Antagonists; Phosphorylation; Protein Kinase C; Quinuclidinyl Benzilate; Receptors, Muscarinic; Salivary Glands; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Phosphorylation of mitogen-activated protein kinase is regulated by protein kinase C, cyclic 3',5'-adenosine monophosphate, and protein phosphatase modulators during meiosis resumption in rat oocytes.
Topics: Animals; Blotting, Western; Cyclic AMP; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Female; Kinetics; Meiosis; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Naphthalenes; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate | 2001 |
Protein kinase C regulates the phosphorylation and cellular localization of occludin.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Calcium; Carcinogens; Cell Line; Cells, Cultured; Cytoplasm; Detergents; Diglycerides; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Indoles; Maleimides; Membrane Proteins; Mice; Microscopy, Fluorescence; Occludin; Octoxynol; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tetradecanoylphorbol Acetate; Tight Junctions; Time Factors | 2001 |
Activation of protein kinase C induces mitogen-activated protein kinase dephosphorylation and pronucleus formation in rat oocytes.
Topics: Animals; Blotting, Western; Cell Nucleus; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Female; Fertilization in Vitro; Male; Meiosis; Mitogen-Activated Protein Kinases; Oocytes; Phosphorylation; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spermatozoa; Tetradecanoylphorbol Acetate | 2002 |
Inhibitory effects of cAMP and protein kinase C on meiotic maturation and MAP kinase phosphorylation in porcine oocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cell Cycle; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Meiosis; Mitogen-Activated Protein Kinases; Oocytes; Phosphorylation; Protein Kinase C; Swine; Tetradecanoylphorbol Acetate | 2002 |
Prolactin signaling in porcine adrenocortical cells: involvement of protein kinases.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Androstenedione; Animals; Diglycerides; Enzyme Activators; Enzyme Inhibitors; Female; Genistein; Hydrocortisone; Ionomycin; Phorbol 12,13-Dibutyrate; Prolactin; Protein Kinase C; Protein-Tyrosine Kinases; Signal Transduction; Sphingosine; Swine; Tetradecanoylphorbol Acetate | 2002 |
Mediation of corticotropin releasing factor type 1 receptor phosphorylation and desensitization by protein kinase C: a possible role in stress adaptation.
Topics: Acclimatization; Animals; COS Cells; Cyclic AMP; Diglycerides; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Gene Expression; Humans; Isoenzymes; Phosphorylation; Protein Kinase C; Receptors, Corticotropin-Releasing Hormone; Stress, Physiological; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tumor Cells, Cultured | 2003 |
Two distinct calcium-sensitive and -insensitive PKC up- and down-regulate an alpha-bungarotoxin-resistant nAChR1 in insect neurosecretory cells (DUM neurons).
Topics: Animals; Bungarotoxins; Calcium; Carcinogens; Diglycerides; Down-Regulation; Enzyme Activation; Immunosuppressive Agents; Male; Membrane Potentials; Neurons; Neurosecretory Systems; Periplaneta; Protein Kinase C; Receptor, Muscarinic M1; Receptors, Muscarinic; Receptors, Nicotinic; Signal Transduction; Tacrolimus; Tetradecanoylphorbol Acetate; Up-Regulation | 2003 |
Phospholipase C and protein kinase C involvement in mouse embryonic stem-cell proliferation and apoptosis.
Topics: Animals; Apoptosis; Calcium; Cell Division; Cell Line; Diglycerides; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Estrenes; Indoles; Inositol Phosphates; Ionomycin; Ionophores; Maleimides; Mice; Phosphatidylinositols; Protein Kinase C; Pyrrolidinones; Signal Transduction; Stem Cells; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Type C Phospholipases | 2003 |
Roles of phospholipase D in phorbol myristate acetate-stimulated neutrophil respiratory burst.
Topics: 1-Butanol; Calcium; Cells, Cultured; Diglycerides; Enzyme Inhibitors; Estrenes; Humans; Indoles; Maleimides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidic Acids; Phosphodiesterase Inhibitors; Phospholipase D; Protein Kinase C; Protein Transport; Pyrrolidinones; Respiratory Burst; Tetradecanoylphorbol Acetate | 2011 |
Protein Kinase Cα (PKCα) Is Resistant to Long Term Desensitization/Down-regulation by Prolonged Diacylglycerol Stimulation.
Topics: Animals; Cell Line, Tumor; Diglycerides; Down-Regulation; Enzyme Activation; Humans; Intestinal Mucosa; Membrane Microdomains; Protein Kinase C-alpha; Protein Transport; Proteolysis; Rats; Signal Transduction; Tetradecanoylphorbol Acetate | 2016 |
Cyclohexane diester analogues of phorbol ester as potential activators of protein kinase C.
Topics: Animals; Brain; Caenorhabditis elegans Proteins; Carrier Proteins; Cyclohexanes; Enzyme Activation; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Structure; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Drug; Structure-Activity Relationship | 1990 |
Binding of curcumin and its long chain derivatives to the activator binding domain of novel protein kinase C.
Topics: Binding Sites; Curcumin; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Kinase C; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization | 2010 |