Page last updated: 2024-08-23

tetrachloroethylene and acetylcysteine

tetrachloroethylene has been researched along with acetylcysteine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Dekant, W; Henschler, D; Metzler, M1
Bartels, MJ1
Dekant, W; Friedewald, M; Lederer, E; Pähler, A; Parker, J; Völkel, W1
Dekant, W; Pähler, A; Völkel, W1
Cichocki, JA; Luo, YS; McDonald, TJ; Rusyn, I1

Other Studies

6 other study(ies) available for tetrachloroethylene and acetylcysteine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Identification of S-1,2,2-trichlorovinyl-N-acetylcysteine as a urinary metabolite of tetrachloroethylene: bioactivation through glutathione conjugation as a possible explanation of its nephrocarcinogenicity.
    Journal of biochemical toxicology, 1986, Volume: 1, Issue:2

    Topics: Acetylcysteine; Animals; Biotransformation; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Feces; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Glutathione Transferase; Kidney Neoplasms; Liver; Mice; Rats; Rats, Inbred Strains; Tetrachloroethylene

1986
Quantitation of the tetrachloroethylene metabolite N-acetyl-S-(trichlorovinyl)cysteine in rat urine via negative ion chemical ionization gas chromatography/tandem mass spectrometry.
    Biological mass spectrometry, 1994, Volume: 23, Issue:11

    Topics: Acetylcysteine; Animals; Gas Chromatography-Mass Spectrometry; Hydroxylamines; Male; Rats; Rats, Inbred F344; Tetrachloroethylene

1994
Biotransformation of perchloroethene: dose-dependent excretion of trichloroacetic acid, dichloroacetic acid, and N-acetyl-S-(trichlorovinyl)-L-cysteine in rats and humans after inhalation.
    Toxicology and applied pharmacology, 1998, Volume: 153, Issue:1

    Topics: Acetylcysteine; Adult; Aged; Animals; Biotransformation; Carcinogens; Dichloroacetic Acid; Environmental Pollutants; Female; Half-Life; Humans; Inhalation Exposure; Male; Middle Aged; Rats; Rats, Wistar; Solvents; Tetrachloroethylene; Trichloroacetic Acid

1998
Gas chromatography-negative ion chemical ionization mass spectrometry as a powerful tool for the detection of mercapturic acids and DNA and protein adducts as biomarkers of exposure to halogenated olefins.
    Journal of chromatography. A, 1999, Jun-25, Volume: 847, Issue:1-2

    Topics: Acetylcysteine; Animals; Biomarkers; Biotransformation; DNA Damage; Gas Chromatography-Mass Spectrometry; Humans; Occupational Exposure; Rats; Reference Standards; Sensitivity and Specificity; Tetrachloroethylene

1999
Simultaneous detection of the tetrachloroethylene metabolites S-(1,2,2-trichlorovinyl) glutathione, S-(1,2,2-trichlorovinyl)-L-cysteine, and N-acetyl-S-(1,2,2-trichlorovinyl)-L-cysteine in multiple mouse tissues via ultra-high performance liquid chromatog
    Journal of toxicology and environmental health. Part A, 2017, Volume: 80, Issue:9

    Topics: Acetylcysteine; Animals; Chromatography, High Pressure Liquid; Glutathione; Mice; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tetrachloroethylene

2017