Page last updated: 2024-08-16

tetracaine and phenytoin

tetracaine has been researched along with phenytoin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's0 (0.00)18.2507
2000's4 (33.33)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Caron, G; Ermondi, G1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Batts, TW; Brown, ML; Jones, PJ; Landry, V; Patel, MK; Wang, Y1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Gozalbes, R; Pineda-Lucena, A1
Brouillette, WJ; Brown, GB; Zha, C1
Lee, EC; Sperelakis, N1
Bartels, E; Rosenberg, P1
FREY, HH1
Burris, KD; Cerne, R; Krambis, MJ; Priest, BT; Wakulchik, M1

Other Studies

12 other study(ies) available for tetracaine and phenytoin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Ligand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophore.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Drug Design; Expert Systems; Inhibitory Concentration 50; Lidocaine; Ligands; Models, Molecular; Phenytoin; Sodium Channel Blockers; Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels

2014
Characterization of (Na + ,K + )-ATPase isolated from embryonic chick hearts and cultured chick heart cells.
    Biochimica et biophysica acta, 1971, Jun-01, Volume: 233, Issue:3

    Topics: Adenosine Triphosphatases; Animals; Barium; Calcium; Cell Fractionation; Cell Line; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Chick Embryo; Chlorides; Enzyme Activation; Heart; Heart Ventricles; Hydrogen-Ion Concentration; Iodides; Kinetics; Lithium; Magnesium; Manganese; Mannitol; Microscopy, Electron; Myocardium; Nickel; Ouabain; Phenytoin; Potassium Chloride; Sodium; Sodium Chloride; Strontium; Subcellular Fractions; Temperature; Tetracaine; Ultracentrifugation; Zinc

1971
Drug effects on the spontaneous electrical activity of the squid giant axon.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:3

    Topics: Acetylcholine; Action Potentials; Animals; Anticonvulsants; Atropine; Axons; Barbiturates; Bromides; Chloroform; Chlorpheniramine; Chlorpromazine; Curare; Dopamine; Electrophysiology; Ethanol; Ethers; Evoked Potentials; Hydantoins; Mollusca; Muscles; Nortropanes; Parasympatholytics; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Procaine; Serotonin; Strychnine; Tetracaine; Tremorine; Trihexyphenidyl; Trimethadione

1967
On the anticonvulsant activity of local anaesthetics.
    Acta pharmacologica et toxicologica, 1962, Volume: 19

    Topics: Anesthesia, Local; Anesthetics, Local; Anticonvulsants; Humans; Lidocaine; Phenobarbital; Phenytoin; Tetracaine

1962
IonWorks Barracuda Assay for Assessment of State-Dependent Sodium Channel Modulators.
    Assay and drug development technologies, 2016, Volume: 14, Issue:2

    Topics: Amitriptyline; Animals; Cells, Cultured; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; HEK293 Cells; High-Throughput Screening Assays; Humans; Lidocaine; NAV1.7 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Phenytoin; Sodium Channel Blockers; Structure-Activity Relationship; Tetracaine

2016