tetra(4-n-methylpyridyl)porphine and pyridostatin

Numerous studies have been published stressing the importance of finding ligands that can bind specifically to DNA secondary structures. Several have identified ligands that are presented as having specific binding to the G-quadruplex; however, these were not originally tested on the complementary i-motif structure. The i-motif was overlooked and presumed to be irrelevant due to the belief that the hemiprotonated (cytosine

Topics: Acridines; Aminoquinolines; Apoptosis Regulatory Proteins; Berberine; Circular Dichroism; G-Quadruplexes; Hydrogen-Ion Concentration; Ligands; Mitoxantrone; Nerve Tissue Proteins; Nucleotide Motifs; Picolinic Acids; Porphyrins; Transition Temperature