Page last updated: 2024-09-04

testololactone and estrone

testololactone has been researched along with estrone in 4 studies

Compound Research Comparison

Studies
(testololactone)
Trials
(testololactone)
Recent Studies (post-2010)
(testololactone)
Studies
(estrone)
Trials
(estrone)
Recent Studies (post-2010) (estrone)
342310,2664321,372

Protein Interaction Comparison

ProteinTaxonomytestololactone (IC50)estrone (IC50)
Estrogen receptorHomo sapiens (human)0.1261
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)6.589
17-beta-hydroxysteroid dehydrogenase type 1Homo sapiens (human)0.4134
Sodium-dependent serotonin transporterHomo sapiens (human)5.301
Estrogen receptor betaHomo sapiens (human)0.3743
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barone, RM; Judd, HL; Shamonki, IM; Siiteri, PK1
Feil, PD; Leszczynski, D; Manni, A; Santen, RJ; Santner, SJ; Tilson-Mallet, N; Wright, C1
Barone, RM; Gambone, JC; Judd, HL; Lasley, BL; Laufer, LR; Monfort, SL1
Budnick, RM; Dao, TL1

Reviews

1 review(s) available for testololactone and estrone

ArticleYear
Enzymatic control of estrogen production in human breast cancer: relative significance of aromatase versus sulfatase pathways.
    Annals of the New York Academy of Sciences, 1986, Volume: 464

    Topics: 17-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aminoglutethimide; Androstenedione; Animals; Aromatase; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Sulfatases; Testolactone

1986

Other Studies

3 other study(ies) available for testololactone and estrone

ArticleYear
Inhibition of peripheral aromatization of androstenedione to estrone in postmenopausal women with breast cancer using delta 1-testololactone.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:5

    Topics: Aged; Androstenedione; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Mastectomy; Menopause; Middle Aged; Steroids, Heterocyclic; Testolactone

1979
In vivo effects of delta 1-testololactone on peripheral aromatization.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Aged; Androstenedione; Aromatase; Breast Neoplasms; Dexamethasone; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged; Oxidoreductases; Testolactone; Testosterone

1982
Inhibition of estrogen synthesis in human breast tumors by testololactone and bromoandrostenedione.
    Steroids, 1980, Volume: 35, Issue:5

    Topics: Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Kinetics; Steroids, Heterocyclic; Testolactone

1980