Page last updated: 2024-09-04

testololactone and androstenedione

testololactone has been researched along with androstenedione in 10 studies

Compound Research Comparison

Studies (testololactone)	Trials (testololactone)	Recent Studies (post-2010) (testololactone)	Studies (androstenedione)	Trials (androstenedione)	Recent Studies (post-2010) (androstenedione)
34	2	3	7,175	377	960

Protein Interaction Comparison

Protein	Taxonomy	androstenedione (IC50)
Cholinesterase	Homo sapiens (human)	1.55
Aromatase	Homo sapiens (human)	0.3
Androgen receptor	Rattus norvegicus (Norway rat)	0.6761
Testosterone 17-beta-dehydrogenase 3	Homo sapiens (human)	0.6826

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (80.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (20.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Al-Aboudi, A; Choudhary, MI; Khalid, A; Naz, Q; Odeh, H	1
Barone, RM; Judd, HL; Shamonki, IM; Siiteri, PK	1
Okada, H; Urabe, M; Yamamoto, T	1
Itagaki, E	1
Feil, PD; Leszczynski, D; Manni, A; Santen, RJ; Santner, SJ; Tilson-Mallet, N; Wright, C	1
Osawa, Y; Rosen, H; Santen, RJ; Santner, SJ	1
Dao, TL	1
Barone, RM; Gambone, JC; Judd, HL; Lasley, BL; Laufer, LR; Monfort, SL	1
Budnick, RM; Dao, TL	1
Kołek, T; Swizdor, A; Szpineter, A	1

Reviews

1 review(s) available for testololactone and androstenedione

Article	Year
Enzymatic control of estrogen production in human breast cancer: relative significance of aromatase versus sulfatase pathways. Annals of the New York Academy of Sciences, 1986, Volume: 464 Topics: 17-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aminoglutethimide; Androstenedione; Animals; Aromatase; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Sulfatases; Testolactone	1986

Article

Year

Enzymatic control of estrogen production in human breast cancer: relative significance of aromatase versus sulfatase pathways.

Annals of the New York Academy of Sciences, 1986, Volume: 464

Topics: 17-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aminoglutethimide; Androstenedione; Animals; Aromatase; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Rats; Sulfatases; Testolactone

1986

Other Studies

9 other study(ies) available for testololactone and androstenedione

Article	Year
Butyrylcholinesterase inhibitory activity of testosterone and some of its metabolites. Journal of enzyme inhibition and medicinal chemistry, 2009, Volume: 24, Issue:2 Topics: Androstenedione; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Enzyme Inhibitors; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Kinetics; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Testosterone	2009
Inhibition of peripheral aromatization of androstenedione to estrone in postmenopausal women with breast cancer using delta 1-testololactone. The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:5 Topics: Aged; Androstenedione; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Mastectomy; Menopause; Middle Aged; Steroids, Heterocyclic; Testolactone	1979
[The inhibitory effect of miconazole on aromatase activity for androstenedione in human placental and ovarian preparations]. Nihon Naibunpi Gakkai zasshi, 1987, Nov-20, Volume: 63, Issue:11 Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Female; Humans; In Vitro Techniques; Miconazole; Ovary; Placenta; Pregnancy; Testolactone	1987
Studies on steroid monooxygenase from Cylindrocarpon radicicola ATCC 11011. Oxygenative lactonization of androstenedione to testololactone. Journal of biochemistry, 1986, Volume: 99, Issue:3 Topics: Androstenedione; Hydrogen-Ion Concentration; Kinetics; Mitosporic Fungi; NADP; Oxidation-Reduction; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Testolactone	1986
Additive effects of aminoglutethimide, testololactone, and 4-hydroxyandrostenedione as inhibitors of aromatase. Journal of steroid biochemistry, 1984, Volume: 20, Issue:6A Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy; Substrate Specificity; Testolactone; Testosterone Congeners	1984
Estrogen synthesis in human breast tumor and its inhibition by testololactone and bromoandrostenedione. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Adrenalectomy; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Castration; Estrogens; Female; Humans; Kinetics; Neoplasm Recurrence, Local; Oxidoreductases; Receptors, Estrogen; Testolactone	1982
In vivo effects of delta 1-testololactone on peripheral aromatization. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Aged; Androstenedione; Aromatase; Breast Neoplasms; Dexamethasone; Dose-Response Relationship, Drug; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged; Oxidoreductases; Testolactone; Testosterone	1982
Inhibition of estrogen synthesis in human breast tumors by testololactone and bromoandrostenedione. Steroids, 1980, Volume: 35, Issue:5 Topics: Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrone; Female; Humans; Kinetics; Steroids, Heterocyclic; Testolactone	1980
Baeyer-Villiger oxidation of DHEA, pregnenolone, and androstenedione by Penicillium lilacinum AM111. Steroids, 2008, Dec-22, Volume: 73, Issue:14 Topics: Androstenedione; Biotransformation; Dehydroepiandrosterone; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Penicillium; Pregnenolone; Testolactone	2008