tesaglitazar has been researched along with fenofibrate in 10 studies
| Studies (tesaglitazar) | Trials (tesaglitazar) | Recent Studies (post-2010) (tesaglitazar) | Studies (fenofibrate) | Trials (fenofibrate) | Recent Studies (post-2010) (fenofibrate) |
|---|---|---|---|---|---|
| 74 | 13 | 25 | 3,058 | 529 | 1,354 |
| Protein | Taxonomy | tesaglitazar (IC50) | fenofibrate (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 2.371 | |
| Adenosine receptor A3 | Homo sapiens (human) | 5.701 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.701 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 2.118 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 2.371 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.701 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 8.633 | |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | 1 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 5.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Henke, BR | 1 |
| Chander, R; Chaturvedi, D; Ray, S; Srivastava, AK | 1 |
| Chae, YN; Chang, DJ; Jung, JW; Kang, HJ; Kim, MK; Kim, NJ; Koo, BW; Le, TV; Lee, KO; Li, F; Lim, JI; Moon, SH; Paek, SM; Park, HJ; Ryu, JS; Shin, CY; Shin, DH; Suh, YG | 1 |
| Abassi, Z; Abu-Saleh, N; Feuerstein, GZ; Goltsman, I; Hansen, MK; Miele, G; Ovcharenko, E; Walsh, K; Winaver, J | 1 |
| Blander, G; Bobadilla, M; Catlett, NL; Deehan, R; Edgar, A; Elliston, KO; Haefliger, C; Ladd, W; Maerz-Weiss, P; Mizrahi, J; Steiner, G; Wong, B; Wright, MB | 1 |
| Blednov, YA; Ferguson, LB; Harris, RA; Most, D | 1 |
| Benavidez, JM; Black, M; Blednov, YA; Edenberg, HJ; Ferguson, LB; Foroud, T; Goate, AM; Harris, RA; Hesselbrock, V; Schoenhard, GL; Wetherill, L | 1 |
| Benavidez, JM; Black, M; Blednov, YA; Harris, RA; Stamatakis, EE | 2 |
| Blednov, YA; Crabbe, JC; Metten, P; Ozburn, AR; Potretzke, S; Townsley, KG | 1 |
1 review(s) available for tesaglitazar and fenofibrate
| Article | Year |
|---|---|
Peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes.
Topics: Animals; Diabetes Mellitus, Type 2; Humans; Hyperglycemia; Hypoglycemic Agents; Models, Molecular; Molecular Structure; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2004 |
9 other study(ies) available for tesaglitazar and fenofibrate
| Article | Year |
|---|---|
Omega-(2-Naphthyloxy) amino alkanes as a novel class of anti-hyperglycemic and lipid lowering agents.
Topics: Alkanes; Alkylation; Amination; Animals; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Metabolism; Male; Molecular Structure; Naphthalenes; PPAR gamma; Rats; Structure-Activity Relationship | 2008 |
Design, synthesis, and biological evaluation of novel constrained meta-substituted phenyl propanoic acids as peroxisome proliferator-activated receptor alpha and gamma dual agonists.
Topics: Animals; Cell Line; Drug Design; Humans; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Structure; Phenylpropionates; PPAR alpha; PPAR gamma; Stereoisomerism; Structure-Activity Relationship; Transcriptional Activation | 2008 |
Peroxisome proliferator-activated receptor alpha and alpha/gamma agonists do not cause impairment in renal function in the rat.
Topics: Alkanesulfonates; Animals; Cell Adhesion Molecules; Creatinine; Fenofibrate; Glomerular Filtration Rate; Hypolipidemic Agents; Inulin; Kidney Tubules; Lipocalin-2; Lipocalins; Male; Osteopontin; Phenylpropionates; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Renal Circulation; RNA, Messenger; Sodium | 2010 |
Comparative transcriptional network modeling of three PPAR-α/γ co-agonists reveals distinct metabolic gene signatures in primary human hepatocytes.
Topics: Alkanesulfonates; Cells, Cultured; Fenofibrate; Hepatocytes; Humans; Oxazoles; Phenylpropionates; Pioglitazone; PPAR alpha; PPAR gamma; Thiazolidinediones; Thiophenes | 2012 |
PPAR agonists regulate brain gene expression: relationship to their effects on ethanol consumption.
Topics: Alcohol Drinking; Alkanesulfonates; Amygdala; Animals; Bezafibrate; Central Nervous System Agents; Central Nervous System Depressants; Drinking; Drinking Water; Ethanol; Fenofibrate; Gene Expression; Liver; Male; Mice, Inbred C57BL; Peroxisome Proliferator-Activated Receptors; Phenylpropionates; Prefrontal Cortex; Taste Perception | 2014 |
Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans.
Topics: Adult; Alcohol Drinking; Alcoholism; Alkanesulfonates; Animals; Bezafibrate; Brain; Female; Fenofibrate; Genome-Wide Association Study; Humans; Liver; Male; Mice; Phenylpropionates; Pioglitazone; Polymorphism, Single Nucleotide; PPAR alpha; PPAR gamma; Thiazoles; Thiazolidinediones | 2015 |
PPAR Agonists: II. Fenofibrate and Tesaglitazar Alter Behaviors Related to Voluntary Alcohol Consumption.
Topics: Alcohol Drinking; Alkanesulfonates; Animals; Avoidance Learning; Conditioning, Classical; Female; Fenofibrate; Locomotion; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Phenylpropionates; PPAR alpha; Reflex, Righting; Taste | 2016 |
PPAR Agonists: I. Role of Receptor Subunits in Alcohol Consumption in Male and Female Mice.
Topics: Alcohol Drinking; Alkanesulfonates; Anilides; Animals; Dose-Response Relationship, Drug; Ethanol; Female; Fenofibrate; Indoles; Male; Mice; Mice, 129 Strain; Mice, Knockout; Phenylpropionates; PPAR alpha; PPAR gamma; Protein Subunits | 2016 |
Effects of Pharmacologically Targeting Neuroimmune Pathways on Alcohol Drinking in Mice Selectively Bred to Drink to Intoxication.
Topics: Alcohol Drinking; Alcoholic Intoxication; Alkanesulfonates; Animals; Binge Drinking; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Fenofibrate; Gabapentin; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Neuroimmunomodulation; Phenylpropionates; Rolipram; Signal Transduction | 2020 |