Compounds > tert-butylbicyclophosphorothionate
Page last updated: 2024-08-26

tert-butylbicyclophosphorothionate and flunitrazepam

tert-butylbicyclophosphorothionate has been researched along with flunitrazepam in 110 studies

Research

Studies (110)

TimeframeStudies, this research(%)All Research%
pre-199044 (40.00)18.7374
1990's58 (52.73)18.2507
2000's7 (6.36)29.6817
2010's1 (0.91)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kukulka, KM; Mans, AM; McAvoy, KJ; Rokosz, NC1
Koenig, JA; Martin, IL1
Kokka, N; Olsen, RW; Sapp, DW; Witte, U1
Blakeman, DP; Carter, DB; Hamilton, BJ; Im, HK; Im, WB; Jacobsen, EJ; Petke, JD; Pregenzer, JF1
Banerjee, PK; Depaulis, A; Hechler, V; Snead, OC; Vergnes, M1
Constantidinis, J; Javoy-Agid, F; Lloyd, GK; Lowenthal, A1
Biggio, G; Concas, A; Gessa, GL; Peduto, VA; Santoro, G1
Lummis, SC; Rauh, JJ; Sattelle, DB; Wong, JF1
Fernandes, G; Mhatre, MC; Ticku, MK1
Chesley, S; Greenblatt, DJ; Lopez, F; Miller, LG; Schatzki, A; Shader, RI; Thompson, ML1
Biggio, G; Concas, A; Foddi, C; Sanna, E; Serra, M1
Breese, GR; Edgar, PP; McCown, TJ; Schwartz, RD1
Biggio, G; Concas, A; Sanna, E; Santoro, G; Serra, M1
Farb, DH; Farrant, M; Roca, DJ; Rozenberg, I1
Kulkarni, SK; Ticku, MK1
Danielou, G; Lloyd, GK; Thuret, F1
Damgaard, I; Saederup, E; Schousboe, A; Squires, RF1
Barnard, EA; Casalotti, SO; Mamalaki, C; Stephenson, FA1
Barker, JL; Harrison, NL; Majewska, MD; Paul, SM; Schwartz, RD1
Havoundjian, H; Skolnick, P; Trullas, R1
Barnard, EA; Bilbe, G; Houamed, K; Moss, SJ; Smart, TG; Van Renterghem, C1
Cole, RJ; Eldefrawi, AT; Eldefrawi, ME; Gant, DB; Valdes, JJ1
McIntyre, TD; Skolnick, P; Trullas, R1
Greenblatt, DJ; Miller, LG; Roy, RB; Shader, RI; Summer, WR1
Saederup, E; Squires, RF1
Biggio, G; Cau, A; Corda, MG; Laudani, U; Longoni, B; Paci, S; Salvadori, S1
Ho, IK; Ito, Y; Lim, DK; Nabeshima, T1
Evoniuk, G; Moody, EJ; Skolnick, P1
Bowen, DM; Cross, AJ; Francis, PT; Green, AR; Robinson, TN; Stirling, JM1
Lopez, F; Miller, LG; Roy, RB; Weill, CL1
Ticku, MK1
Maksay, G; Simonyi, M2
Ho, IK; Hoskins, B; Ito, Y; Lim, DK1
Braestrup, C; Nielsen, M1
Evoniuk, G; Skolnick, P1
Gaver, A; Miller, LG; Roy, RB; Weill, CL1
Abalis, IM; Eldefrawi, AT; Eldefrawi, ME1
Chiu, TH; Ito, M; Yu, O1
Richter, JA; Yamamura, HI1
Komiskey, HL; Meyers, MB1
Barnes, EM; Tehrani, MH1
Haefely, W; Möhler, H; Richards, JG; Schoch, P1
Stephenson, FA2
Cohen, RM; Havoundjian, H; Paul, SM; Skolnick, P1
Havoundjian, H; Paul, SM; Skolnick, P2
Chiu, TH; Ito, M; Rosenberg, HC1
Häring, P; Mohler, H; Richards, JG; Schoch, P; Takacs, B1
Clothier, J; Rastogi, SK; Thyagarajan, R; Ticku, MK1
Crofton, KM; Mailman, RB; Reiter, LW1
Havoundjian, H; Skolnick, P1
Havoundjian, H; Paul, S; Skolnick, P; Trullas, R; Zamir, N1
Havoundjian, H; Paul, S; Skolnick, P; Trullas, R1
Barker, JL; Harrington, JW; Harrison, NL; Majewska, MD1
Becker, CM; Betz, H; Rienitz, A; Schmitt, B1
Crabbe, JC; Feller, DJ; Harris, RA1
Braestrup, C; Tacke, U1
Gee, KW; Wamsley, JK; Yamamura, HI1
Barnard, EA; Sigel, E1
Frandsen, A; Pomés, A; Rodríguez-Farré, E; Sanfeliu, C; Schousboe, A; Suñol, C1
Cancedda, E; Corda, MG; Giorgi, O; Lecca, D; Serra, GP1
Camón, L; Martínez, E; Pazos, A; Rodríguez-Farré, E; Solà, C1
Burnham, WM; Lôscher, W; Nobrega, JN; Richter, A1
Bolger, MB; Gee, KW; Hawkinson, JE; Kimbrough, CL; Lan, NC; McCauley, LD1
Barnes, EM; Baumgartner, BJ; Calkin, PA1
Clark, M; Massenburg, GS; Post, RM; Weiss, SR1
Chen, JS; Gee, KW; Hawkinson, JE; Lan, NC; Liu, V; McCauley, LD1
Allan, AM; Harris, RA; McQuilkin, SJ; Mihic, SJ; Whatley, VJ1
Cancedda, E; Corda, MG; Giorgi, O; Lecca, D; Orlandi, M1
Harris, RA; Klein, RL; McQuilkin, SJ; Sanna, E; Whiting, PJ1
Belelli, D; Hawkinson, JE; Kimbrough, CL; Lambert, JJ; Lan, NC; Purdy, RH1
Belelli, D; Chen, R; Lambert, JJ; Lan, NC; Peters, JA; Reyes, A1
Ho, IK; Kim, HS; Kimura, T; Oh, KW; Rheu, HM; Saunders, PA1
Deutsch, SI; Hitri, A; Park, CH1
Moore, FL; Murray, TF; Orchinik, M1
Crawley, JN; Drugan, RC; Paul, SM1
Corda, MG; Driscoll, P; Escorihuela, RM; Giorgi, O; Lecca, D; Orlandi, M1
Airaksinen, MM; Nieminen, SA; Railoma, O; Titievsky, AV1
Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Ongini, E; Santoro, G1
Liljequist, S; Tabakoff, B1
Liu, CC; Snead, OC1
Belfiore, MS; Giusti, L; Lucacchini, A; Martini, C1
Carter, DB; Im, WB; Pregenzer, JF; Thomsen, DR1
Ho, IK; Miyaoka, T; Tseng, YT1
Anderson, SM; Cross, AJ; De Souza, RJ1
Harris, BD; Moody, EJ; Skolnick, P1
Belonga, KL; Carter, DB; Im, HK; Im, WB; Jacobsen, EJ; Petke, JD; Sethy, VH; Stelzer, LS; Tang, AH; TenBrink, RE; VonVoigtlander, PF1
Devaud, LL; Morrow, AL; Paul, SM; Purdy, RH1
Biggio, G; Ghiani, CA; Maciocco, E; Sanna, E; Serra, M; Tuligi, G1
Friend, JM; Gee, KW; Xue, BG1
Sieghart, W; Slany, A; Zezula, J1
Karle, J; Nielsen, M; Witt, MR1
Belelli, D; Bolger, MB; Carter, RB; Gee, KW; Hawkinson, JE; Lambert, JJ; Lan, NC; Mirsadeghi, S; Tahir, SH; White, HS; Wieland, S; Wolf, HH; Wood, PL1
Buckingham, SD; Rauh, J; Sattelle, DB; Schnee, M1
Barnes, EM; Baumgartner, BJ; Tehrani, MH1
Im, HK; Im, WB; Jacobsen, EJ; Pregenzer, JF; Stratman, NC; VonVoigtlander, PF1
Mehta, AK; Ticku, MK2
Acosta-Burruel, M; Carter, RB; Chen, JS; Drewe, JA; Hawkinson, JE; Hogenkamp, DJ; Lan, NC; Upasani, RB; Whittemore, ER; Woodward, RM; Yang, KC1
Barbaccia, ML; Biggio, G; Concas, A; Follesa, P; Purdy, RH1
Ho, IK; Jang, CG; Ma, T; Oh, S1
Burton, G; Dodd, RH; Furtmüller, R; Ghini, AA; Nicoletti, D; Sieghart, W1
Carroll, SS; Li, YH; McEwen, BS; Orchinik, M; Weiland, NG1
Altomare, C; Biggio, G; Busonero, F; Carotti, A; Chiasserini, L; Maciocco, E; Mameli, M; Mascia, MP; Pellerano, C; Sanna, E; Savini, L1
Abuhamdah, S; Chazot, PL; Fürstner, A; Lees, G1
Fan, LW; Ho, IK; Loh, HH; Ma, T; Tien, LT1
Bédard, PJ; Belanger, N; Calon, F; Di Paolo, T; Dridi, M; Hadj Tahar, A; Meltzer, LT; Morissette, M; Samadi, P1
Burton, G; Coirini, H; Ghini, AA; Kruse, MS; Rey, M; Veleiro, AS1

Reviews

2 review(s) available for tert-butylbicyclophosphorothionate and flunitrazepam

ArticleYear
Benzodiazepine receptors resolved.
    Experientia, 1986, Feb-15, Volume: 42, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Autoradiography; Benzodiazepines; Benzodiazepinones; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Clonazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Histocytochemistry; Humans; Immunologic Techniques; Ionophores; Muscimol; Neurons; Radioisotopes; Radioligand Assay; Receptors, GABA-A; Spinal Cord; Synapses; Tissue Distribution

1986
Neuroactive steroid modulators of the stress response.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 771

    Topics: Adrenalectomy; Alcoholism; Animals; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Estrus; Female; Flunitrazepam; Hypothalamo-Hypophyseal System; Male; Menstruation; Pregnancy; Pregnanolone; Pregnenolone; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Stress, Physiological

1995

Other Studies

108 other study(ies) available for tert-butylbicyclophosphorothionate and flunitrazepam

ArticleYear
Regional distribution and kinetics of three sites on the GABAA receptor: lack of effect of portacaval shunting.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:2

    Topics: Animals; Autoradiography; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Flumazenil; Flunitrazepam; Image Processing, Computer-Assisted; Kinetics; Male; Muscimol; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tissue Distribution

1992
Effect of free fatty acids on GABAA receptor ligand binding.
    Biochemical pharmacology, 1992, Jul-07, Volume: 44, Issue:1

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Fatty Acids, Nonesterified; Flunitrazepam; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A

1992
Sex differences in sensitivity to pentylenetetrazol but not in GABAA receptor binding.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:2

    Topics: Anesthetics; Animals; Anticonvulsants; Autoradiography; Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Diazepam; Electroshock; Ethanol; Female; Flunitrazepam; Male; Muscimol; Orchiectomy; Ovariectomy; Pentylenetetrazole; Pregnanediones; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Sex Characteristics

1992
Characterization of functional interactions of imidazoquinoxaline derivatives with benzodiazepine-gamma-aminobutyric acidA receptors.
    Molecular pharmacology, 1992, Volume: 42, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Chlorides; Chlorine; Cloning, Molecular; Drug Interactions; Electrophysiology; Flunitrazepam; GABA-A Receptor Antagonists; Kinetics; Male; Membrane Proteins; Models, Chemical; Molecular Conformation; Oxadiazoles; Quinoxalines; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Structure-Activity Relationship; Synaptosomes; Tritium

1992
The GABAA receptor complex in experimental absence seizures in rat: an autoradiographic study.
    Neuroscience letters, 1992, Jun-08, Volume: 140, Issue:1

    Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Convulsants; Epilepsy, Absence; Flunitrazepam; GABA-A Receptor Antagonists; Ion Channels; Ionophores; Male; Membrane Proteins; Muscimol; Organ Specificity; Pyramidal Tracts; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Sulfur Radioisotopes; Tritium

1992
GABAA receptor complex function in frontal cortex membranes from control and neurological patients.
    European journal of pharmacology, 1991, May-02, Volume: 197, Issue:1

    Topics: Adult; Aged; Alzheimer Disease; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Clonazepam; Female; Flunitrazepam; Humans; Huntington Disease; Imidazoles; In Vitro Techniques; Kinetics; Male; Membranes; Middle Aged; Nervous System Diseases; Parkinson Disease; Pyridines; Receptors, GABA-A

1991
Biochemical and electrophysiologic evidence that propofol enhances GABAergic transmission in the rat brain.
    Anesthesiology, 1991, Volume: 75, Issue:6

    Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Male; Membrane Proteins; Propofol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission

1991
Pharmacology of insect GABA receptors.
    Neurochemical research, 1991, Volume: 16, Issue:3

    Topics: Acetylcholine; Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Female; Flunitrazepam; gamma-Aminobutyric Acid; Houseflies; Insecticides; Male; Membrane Proteins; Nervous System; Neurons; Periplaneta; Pregnanes; Receptors, GABA-A; Synapses

1991
Aging reduces the mRNA of alpha 1 GABAA receptor subunit in rat cerebral cortex.
    European journal of pharmacology, 1991, Oct-14, Volume: 208, Issue:2

    Topics: Aging; Animals; Blotting, Northern; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression Regulation; Macromolecular Substances; Male; Rats; Rats, Inbred F344; Receptors, GABA-A; RNA, Messenger; Transcription, Genetic; Tritium

1991
Chronic morphine administration augments benzodiazepine binding and GABAA receptor function.
    Psychopharmacology, 1990, Volume: 101, Issue:4

    Topics: Animals; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Chlorine; Flunitrazepam; In Vitro Techniques; Ion Channels; Male; Mice; Morphine; Muscimol; Naltrexone; Radioisotopes; Receptors, GABA-A; Sulfur Radioisotopes

1990
Failure of gamma-hydroxybutyrate to alter the function of the GABAA receptor complex in the rat cerebral cortex.
    Psychopharmacology, 1991, Volume: 104, Issue:3

    Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Diazepam; Flunitrazepam; In Vitro Techniques; Ion Channels; Isoniazid; Male; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Oxybate; Synaptic Transmission

1991
Unilateral kindling of the inferior collicular cortex does not transfer to the contralateral seizure sensitive site or alter [3H]flunitrazepam and [35S]TBPS binding.
    Epilepsy research, 1991, Volume: 9, Issue:2

    Topics: Animals; Autoradiography; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Electroencephalography; Flunitrazepam; Inferior Colliculi; Kindling, Neurologic; Rats; Rats, Inbred Strains; Seizures

1991
Neurochemical action of the general anaesthetic propofol on the chloride ion channel coupled with GABAA receptors.
    Brain research, 1991, Mar-01, Volume: 542, Issue:2

    Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Flunitrazepam; Male; Membrane Proteins; Muscimol; Propofol; Rats; Rats, Inbred Strains; Receptors, GABA-A

1991
Chronic agonist exposure induces down-regulation and allosteric uncoupling of the gamma-aminobutyric acid/benzodiazepine receptor complex.
    Molecular pharmacology, 1990, Volume: 37, Issue:1

    Topics: Allosteric Regulation; Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chick Embryo; Down-Regulation; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Pyridazines; Receptors, GABA-A

1990
Chronic benzodiazepine antagonist treatment and its withdrawal upregulates components of GABA-benzodiazepine receptor ionophore complex in cerebral cortex of rat.
    Brain research, 1990, Jun-11, Volume: 519, Issue:1-2

    Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Up-Regulation

1990
The activity of zolpidem and other hypnotics within the gamma-aminobutyric acid (GABAA) receptor supramolecular complex, as determined by 35S-t-butylbicyclophosphorothionate (35S-TBPS) binding to rat cerebral cortex membranes.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Zolpidem

1990
Development of benzodiazepine and picrotoxin (t-butylbicyclophosphorothionate) binding sites in rat cerebellar granule cells in culture.
    Journal of neurochemistry, 1990, Volume: 54, Issue:2

    Topics: Animals; Benzodiazepines; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cells, Cultured; Cerebellum; Flunitrazepam; Granulocytes; Isoxazoles; Pyrazoles; Pyridazines; Pyridines; Rats

1990
Antibodies recognising the GABAA/benzodiazepine receptor including its regulatory sites.
    Journal of neurochemistry, 1986, Volume: 46, Issue:3

    Topics: Allosteric Regulation; Animals; Antibodies; Antibody Specificity; Antigens; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cattle; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Epitopes; Flunitrazepam; Immunologic Techniques; Immunosorbent Techniques; Muscimol; Receptors, GABA-A

1986
Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor.
    Science (New York, N.Y.), 1986, May-23, Volume: 232, Issue:4753

    Topics: 20-alpha-Dihydroprogesterone; Animals; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chlorides; Desoxycorticosterone; Drug Synergism; Flunitrazepam; Hippocampus; In Vitro Techniques; Ion Channels; Progesterone; Rats; Receptors, GABA-A; Spinal Cord

1986
Stress-induced changes in t-[35S]butylbicyclophosphorothionate binding to gamma-aminobutyric acid-gated chloride channels are mimicked by in vitro occupation of benzodiazepine receptors.
    Journal of neurochemistry, 1987, Volume: 49, Issue:3

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebral Cortex; Chlorides; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Swimming

1987
Functional expression in the Xenopus oocyte of messenger ribonucleic acids encoding brain neurotransmitter receptors: further characterisation of the implanted GABA receptor.
    Neuropharmacology, 1987, Volume: 26, Issue:7B

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Chlorides; Cloning, Molecular; DNA; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression Regulation; Glycosylation; Ion Channels; Oocytes; Poly A; Receptors, GABA-A; RNA; RNA, Messenger; Xenopus

1987
Action of tremorgenic mycotoxins on GABAA receptor.
    Life sciences, 1987, Nov-09, Volume: 41, Issue:19

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Electric Organ; Flunitrazepam; In Vitro Techniques; Ion Channels; Male; Muscimol; Mycotoxins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Torpedo; Tremor

1987
Differences in the biophysical properties of the benzodiazepine/gamma-aminobutyric acid receptor chloride channel complex in the long-sleep and short-sleep mouse lines.
    Journal of neurochemistry, 1988, Volume: 51, Issue:2

    Topics: Animals; Azides; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; Heart; Ion Channels; Male; Mice; Mice, Mutant Strains; Receptors, GABA-A; Sleep

1988
Chronic benzodiazepine administration. II. Discontinuation syndrome is associated with upregulation of gamma-aminobutyric acidA receptor complex binding and function.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1

    Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Drug Tolerance; Flumazenil; Flunitrazepam; Ion Channels; Lorazepam; Male; Mice; Motor Activity; Muscimol; Receptors, GABA-A; Time Factors

1988
Polychlorinated convulsant insecticides potentiate the protective effect of NaCl against heat inactivation of [3H]flunitrazepam binding sites.
    Journal of neurochemistry, 1989, Volume: 52, Issue:2

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Child, Preschool; Dieldrin; Drug Synergism; Endosulfan; Endrin; Flunitrazepam; Hexachlorocyclohexane; Hot Temperature; Humans; Insecticides; Rats; Receptors, GABA-A; Sodium Chloride; Toxaphene

1989
Distribution and pharmacological properties of the GABAA/benzodiazepine/chloride ionophore receptor complex in the brain of the fish Anguilla anguilla.
    Journal of neurochemistry, 1989, Volume: 52, Issue:4

    Topics: Anguilla; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; Ionophores; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Drug; Receptors, GABA-A; Tissue Distribution

1989
Effects of picrotoxin treatment on GABAA receptor supramolecular complexes in rat brain.
    Journal of neurochemistry, 1989, Volume: 52, Issue:4

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Flunitrazepam; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Tissue Distribution

1989
Ultraviolet irradiation selectively disrupts the gamma-aminobutyric acid/benzodiazepine receptor-linked chloride ionophore.
    Molecular pharmacology, 1989, Volume: 35, Issue:5

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Chloride Channels; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Proteins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Ultraviolet Rays

1989
The modulation by chlormethiazole of the GABAA-receptor complex in rat brain.
    British journal of pharmacology, 1989, Volume: 98, Issue:1

    Topics: Animals; Baclofen; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlormethiazole; CLC-2 Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA-A

1989
Persistent alterations in GABAA receptor binding and function after prenatal lorazepam administration in the chick.
    Brain research bulletin, 1989, Volume: 23, Issue:3

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Chickens; Chlorides; Female; Flunitrazepam; Lorazepam; Muscimol; Pregnancy; Prenatal Exposure Delayed Effects; Radioligand Assay; Receptors, GABA-A

1989
Behavioral and functional studies indicate a role for GABAAergic transmission in the actions of ethanol.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1987, Volume: 1

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Ethanol; Flunitrazepam; Male; Mice; Mice, Inbred C57BL; Picrotoxin; Rats; Receptors, GABA-A; Seizures; Spinal Cord

1987
Nonequilibrium modulation of 35S-TBPS binding by benzodiazepine agonists and antagonists.
    Biochemical pharmacology, 1988, Jun-01, Volume: 37, Issue:11

    Topics: Animals; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Diazepam; Flunitrazepam; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Structure-Activity Relationship

1988
Bicuculline up-regulation of GABAA receptors in rat brain.
    Journal of neurochemistry, 1988, Volume: 51, Issue:1

    Topics: Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Corpus Striatum; Flunitrazepam; Frontal Lobe; gamma-Aminobutyric Acid; Male; Muscimol; Octoxynol; Polyethylene Glycols; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Synaptic Membranes

1988
The apparent target size of rat brain benzodiazepine receptor, acetylcholinesterase, and pyruvate kinase is highly influenced by experimental conditions.
    The Journal of biological chemistry, 1988, Aug-25, Volume: 263, Issue:24

    Topics: Acetylcholinesterase; Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Flunitrazepam; Freeze Drying; Freezing; Ketanserin; Male; Molecular Weight; Muscles; Pyruvate Kinase; Quinuclidinyl Benzilate; Rabbits; Rats; Rats, Inbred Strains; Receptors, GABA-A

1988
Picrate and niflumate block anion modulation of radioligand binding to the gamma-aminobutyric acid/benzodiazepine receptor complex.
    Molecular pharmacology, 1988, Volume: 34, Issue:6

    Topics: Animals; Anions; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Flunitrazepam; Male; Nicotinic Acids; Niflumic Acid; Picrates; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A

1988
Lorazepam administration during embryonic development alters GABAA receptor binding and function.
    Brain research. Developmental brain research, 1988, Dec-01, Volume: 44, Issue:2

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chick Embryo; Chlorides; Embryonic and Fetal Development; Flunitrazepam; Lorazepam; Receptors, GABA-A; Subcellular Fractions

1988
Actions of avermectin B1a on the gamma-aminobutyric acidA receptor and chloride channels in rat brain.
    Journal of biochemical toxicology, 1986, Volume: 1, Issue:1

    Topics: Animals; Bicuculline; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Chlorides; Dose-Response Relationship, Drug; Flunitrazepam; Ivermectin; Kinetics; Male; Membrane Proteins; Muscimol; Rats; Receptors, GABA-A

1986
Interactions of ACTH4-10 and ACTH1-24 with L-[3H]glutamate binding sites and GABA/benzodiazepine/picrotoxin receptor complexes in vitro.
    Brain & development, 1988, Volume: 10, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; Glutamates; Glutamic Acid; Male; Muscimol; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Glutamate; Receptors, Neurotransmitter

1988
Effects of pentobarbital on t-[35S]butylbicyclophosphorothionate and [3H]flunitrazepam binding to membrane-bound and solubilized preparations from rat forebrain.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cholic Acids; Flunitrazepam; Kinetics; Pentobarbital; Rats; Receptors, GABA-A; Receptors, Neurotransmitter; Solubility; Temperature

1985
Aging: effect on the interaction of ethanol and pentobarbital with the benzodiazepine-GABA receptor-ionophore complex.
    Brain research, 1985, Sep-23, Volume: 343, Issue:2

    Topics: Aging; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Ethanol; Flunitrazepam; gamma-Aminobutyric Acid; Ionophores; Kinetics; Male; Pentobarbital; Rats; Rats, Inbred F344; Receptors, GABA-A; Temperature

1985
Benzodiazepine anticonvulsants accelerate and beta-carboline convulsants decelerate the kinetics of [35S]TBPS binding at the chloride ionophore.
    European journal of pharmacology, 1985, Nov-05, Volume: 117, Issue:2

    Topics: Animals; Anticonvulsants; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Chlorides; Convulsants; Flunitrazepam; In Vitro Techniques; Ionophores; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes

1985
Ontogeny of the GABA receptor complex in chick brain: studies in vivo and in vitro.
    Brain research, 1986, Volume: 390, Issue:1

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chick Embryo; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Receptors, GABA-A

1986
Isolation of the gamma-aminobutyric acid/benzodiazepine receptor.
    Biochemical Society transactions, 1985, Volume: 13, Issue:6

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Chromatography, Affinity; Flunitrazepam; Isoelectric Point; Molecular Weight; Muscimol; Radioimmunoassay; Rats; Receptors, GABA-A

1985
Differential sensitivity of "central" and "peripheral" type benzodiazepine receptors to phospholipase A2.
    Journal of neurochemistry, 1986, Volume: 46, Issue:3

    Topics: Animals; Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Cerebral Cortex; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Kidney; Male; Myocardium; Pentobarbital; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A

1986
Acute, stress-induced changes in the benzodiazepine/gamma-aminobutyric acid receptor complex are confined to the chloride ionophore.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bromides; Cerebral Cortex; Chlorides; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Iodides; Ionophores; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Sulfur Radioisotopes; Swimming; Tritium

1986
Effects of pentylenetetrazol on GABA-A/benzodiazepine/picrotoxinin receptor complexes in rat brain regions.
    Neurochemical research, 1986, Volume: 11, Issue:5

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Corpus Striatum; Flunitrazepam; gamma-Aminobutyric Acid; Male; Muscimol; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Tissue Distribution

1986
Rapid, stress-induced modification of the benzodiazepine receptor-coupled chloride ionophore.
    Brain research, 1986, Jun-11, Volume: 375, Issue:2

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Flunitrazepam; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical; Stress, Physiological; Swimming; Temperature

1986
Structural analysis and localization of GABA/benzodiazepine/TBPS-receptor complex using monoclonal antibodies.
    Advances in biochemical psychopharmacology, 1986, Volume: 41

    Topics: Animals; Antibodies, Monoclonal; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Convulsants; Flunitrazepam; Humans; Immunoenzyme Techniques; Mice; Muscimol; Rats; Receptors, GABA-A; Sulfur Radioisotopes; Tritium

1986
Effect of chronic treatment of ethanol on benzodiazepine and picrotoxin sites on the GABA receptor complex in regions of the brain of the rat.
    Neuropharmacology, 1986, Volume: 25, Issue:10

    Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Corpus Striatum; Ethanol; Flunitrazepam; Hippocampus; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A

1986
Pyrethroid insecticides and radioligand displacement from the GABA receptor chloride ionophore complex.
    Toxicology letters, 1987, Volume: 35, Issue:2-3

    Topics: Animals; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; Male; Muscimol; Nitriles; Permethrin; Pyrethrins; Rats; Receptors, GABA-A

1987
A quantitative relationship between Cl- enhanced [3H]flunitrazepam and [35S]t-butylbicyclophosphorothionate binding to the benzodiazepine/GABA receptor chloride ionophore complex.
    Brain research, 1986, Volume: 387, Issue:3

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebral Cortex; Chlorides; Flunitrazepam; In Vitro Techniques; Male; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stimulation, Chemical

1986
Environmentally-induced modification of the benzodiazepine/GABA receptor coupled chloride ionophore.
    Psychopharmacology, 1987, Volume: 91, Issue:3

    Topics: Animals; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Environment; Flunitrazepam; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Swimming

1987
The benzodiazepine/GABA receptor complex in anxiety.
    Clinical neuropharmacology, 1986, Volume: 9 Suppl 4

    Topics: Animals; Anxiety; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; gamma-Aminobutyric Acid; Rats; Receptors, GABA-A; Stress, Physiological

1986
Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Desoxycorticosterone; Electric Conductivity; Ethanol; Evoked Potentials; Flunitrazepam; Muscimol; Pregnanes; Progesterone; Rats; Rats, Inbred Strains; Receptors, GABA-A; Steroids; Structure-Activity Relationship

1987
The chloride channel blocking agent, t-butyl bicyclophosphorothionate, binds to the gamma-aminobutyric acid-benzodiazepine, but not to the glycine receptor in rodents.
    Neuroscience letters, 1987, Apr-23, Volume: 76, Issue:1

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebellum; Flunitrazepam; Glycine; Mice; Mice, Neurologic Mutants; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, Neurotransmitter; Spinal Cord; Strychnine; Synaptic Membranes

1987
Progress towards the understanding of the GABAA receptor structure.
    Journal of receptor research, 1987, Volume: 7, Issue:1-4

    Topics: Allosteric Site; Animals; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Cholic Acids; Deoxycholic Acid; Flunitrazepam; gamma-Aminobutyric Acid; Muscimol; Protein Binding; Receptors, GABA-A

1987
Differences in GABA activity between ethanol withdrawal seizure prone and resistant mice.
    European journal of pharmacology, 1988, Nov-22, Volume: 157, Issue:2-3

    Topics: Animals; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Ethanol; Female; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Picrotoxin; Seizures; Substance Withdrawal Syndrome

1988
A study on benzodiazepine receptor binding in audiogenic seizure-susceptible rats.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:3

    Topics: Acoustic Stimulation; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Convulsants; Diazepam; Female; Flunitrazepam; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures

1984
Comparison of the distribution of convulsant/barbiturate and benzodiazepine receptors using light microscopic autoradiography.
    Life sciences, 1983, Dec-05, Volume: 33, Issue:23

    Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; In Vitro Techniques; Male; Microscopy; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Sulfur Radioisotopes

1983
A gamma-aminobutyric acid/benzodiazepine receptor complex from bovine cerebral cortex. Improved purification with preservation of regulatory sites and their interactions.
    The Journal of biological chemistry, 1984, Jun-10, Volume: 259, Issue:11

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Cholic Acids; Flunitrazepam; gamma-Aminobutyric Acid; Kinetics; Methods; Muscimol; Pentobarbital; Receptors, Cell Surface; Receptors, GABA-A; Solubility

1984
Lindane cytotoxicity in cultured neocortical neurons is ameliorated by GABA and flunitrazepam.
    Journal of neuroscience research, 1994, Dec-15, Volume: 39, Issue:6

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Chloride Channels; Chlorine; Convulsants; Flunitrazepam; gamma-Aminobutyric Acid; Hexachlorocyclohexane; Mice; Neurons; Potassium; Receptors, GABA

1994
Modulation of [35S]TBPS binding by ligands with preferential affinity for benzodiazepine BZ1 sites in the cerebral cortex of newborn and adult rats.
    European journal of pharmacology, 1995, Jun-23, Volume: 290, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Female; Flunitrazepam; Male; Pregnancy; Pyridazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zolpidem

1995
Lindane administration to the rat induces modifications in the regional cerebral binding of [3H]Muscimol, [3H]-flunitrazepam, and t-[35S]butylbicyclophosphorothionate: an autoradiographic study.
    Journal of neurochemistry, 1993, Volume: 60, Issue:5

    Topics: Animals; Autoradiography; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Flunitrazepam; Hexachlorocyclohexane; Male; Muscimol; Rats; Rats, Wistar; Reference Values; Sulfur Radioisotopes; Tissue Distribution; Tritium

1993
Alterations in the brain GABAA/benzodiazepine receptor-chloride ionophore complex in a genetic model of paroxysmal dystonia: a quantitative autoradiographic analysis.
    Neuroscience, 1995, Volume: 64, Issue:1

    Topics: Animals; Autoradiography; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Cricetinae; Dystonia; Flunitrazepam; Ionophores; Male; Models, Genetic; Muscimol; Radiography; Receptors, GABA-A

1995
The neuroactive steroid 3 alpha-hydroxy-5 beta-pregnan-20-one is a two-component modulator of ligand binding to the GABAA receptor.
    European journal of pharmacology, 1994, Oct-14, Volume: 269, Issue:2

    Topics: 20-alpha-Dihydroprogesterone; Animals; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebellum; Convulsants; Flunitrazepam; Hippocampus; In Vitro Techniques; Ligands; Male; Membranes; Receptors, GABA-A; Thalamus

1994
Agonist administration in ovo down-regulates cerebellar GABAA receptors in the chick embryo.
    Brain research. Molecular brain research, 1994, Volume: 26, Issue:1-2

    Topics: Allantois; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebellum; Chick Embryo; Chorion; Convulsants; Down-Regulation; Flunitrazepam; GABA Agonists; Isonicotinic Acids; Kinetics; Macromolecular Substances; Polymerase Chain Reaction; Radioligand Assay; Receptors, GABA; RNA, Messenger

1994
Analysis of the hippocampal GABAA receptor system in kindled rats by autoradiographic and in situ hybridization techniques: contingent tolerance to carbamazepine.
    Brain research. Molecular brain research, 1994, Volume: 26, Issue:1-2

    Topics: Affinity Labels; Amygdala; Animals; Autoradiography; Azides; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbamazepine; Convulsants; Drug Tolerance; Electric Stimulation; Electroencephalography; Flunitrazepam; Functional Laterality; Gene Expression; Hippocampus; In Situ Hybridization; Kindling, Neurologic; Macromolecular Substances; Muscimol; Neurons; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Seizures; Tritium

1994
Selective actions of certain neuroactive pregnanediols at the gamma-aminobutyric acid type A receptor complex in rat brain.
    Molecular pharmacology, 1995, Volume: 47, Issue:2

    Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Flunitrazepam; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Pregnanediol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

1995
Gamma-aminobutyric acidA receptor function is inhibited by microtubule depolymerization.
    The Journal of biological chemistry, 1994, Jul-29, Volume: 269, Issue:30

    Topics: Animals; Biological Transport; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Chlorides; Colchicine; Convulsants; Dose-Response Relationship, Drug; Flunitrazepam; Histones; Humans; Lumicolchicines; Membranes; Mice; Microtubules; Muscimol; Nocodazole; Paclitaxel; Phosphorylation; Receptors, GABA-A; Vinblastine; Xenopus

1994
Allosteric modulation of [35S]TBPS-binding in the cerebral cortex of the rat during postnatal development.
    Brain research. Developmental brain research, 1994, Jul-15, Volume: 80, Issue:1-2

    Topics: Aging; Allosteric Regulation; Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Convulsants; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereoisomerism; Sulfur Radioisotopes

1994
Effects of 5-HT3 receptor antagonists on binding and function of mouse and human GABAA receptors.
    European journal of pharmacology, 1994, Jul-15, Volume: 268, Issue:2

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flumazenil; Flunitrazepam; Humans; Indazoles; Indoles; Male; Mice; Mice, Inbred ICR; Receptors, GABA-A; Serotonin Antagonists; Tropanes; Tropisetron; Xenopus laevis

1994
Correlation of neuroactive steroid modulation of [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding and gamma-aminobutyric acidA receptor function.
    Molecular pharmacology, 1994, Volume: 46, Issue:5

    Topics: Allosteric Regulation; Androstanes; Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; In Vitro Techniques; Membrane Potentials; Pregnanes; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis

1994
Cloning and functional expression of a Drosophila gamma-aminobutyric acid receptor.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Jun-21, Volume: 91, Issue:13

    Topics: Amino Acid Sequence; Animals; Base Sequence; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cloning, Molecular; Convulsants; DNA Primers; DNA, Complementary; Drosophila melanogaster; Female; Flunitrazepam; gamma-Aminobutyric Acid; Gene Expression; Macromolecular Substances; Molecular Sequence Data; Muscimol; Oocytes; Pentobarbital; Picrotoxin; Polymerase Chain Reaction; Receptors, GABA; Receptors, GABA-A; Transcription, Genetic; Xenopus laevis

1994
Interactions of ginsenosides with ligand-bindings of GABA(A) and GABA(B) receptors.
    General pharmacology, 1994, Volume: 25, Issue:1

    Topics: Animals; Baclofen; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbohydrate Sequence; Flunitrazepam; Ginsenosides; Herb-Drug Interactions; Ligands; Male; Molecular Sequence Data; Muscimol; Panax; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Saponins; Sulfur Radioisotopes; Tritium

1994
Allosteric effects of a GABA receptor-active steroid are altered by stress.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:4

    Topics: Allosteric Regulation; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Desoxycorticosterone; Flunitrazepam; In Vitro Techniques; Ion Channel Gating; Kinetics; Male; Mice; Receptors, GABA; Stress, Physiological

1994
Steroid modulation of GABAA receptors in an amphibian brain.
    Brain research, 1994, May-23, Volume: 646, Issue:2

    Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chlorides; Convulsants; Corticosterone; Flunitrazepam; Kinetics; Male; Mammals; Neurons; Pregnanolone; Pregnenolone; Rats; Receptors, GABA-A; Salamandridae; Species Specificity; Steroids; Sulfur Radioisotopes; Synaptosomes; Tritium

1994
Decreased forebrain [35S]TBPS binding and increased [3H]muscimol binding in rats that do not develop stress-induced behavioral depression.
    Brain research, 1993, Dec-24, Volume: 631, Issue:2

    Topics: Adrenalectomy; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Depression; Desoxycorticosterone; Electroshock; Flunitrazepam; Helplessness, Learned; Male; Muscimol; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stress, Psychological

1993
GABAergic and dopaminergic transmission in the brain of Roman high-avoidance and Roman low-avoidance rats.
    Brain research, 1994, Feb-28, Volume: 638, Issue:1-2

    Topics: Amygdala; Animals; Avoidance Learning; Benzazepines; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Chlorides; Convulsants; Corpus Striatum; Dopamine; Emotions; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Male; Nucleus Accumbens; Organ Specificity; Prefrontal Cortex; Rats; Rats, Mutant Strains; Receptors, Dopamine D1; Species Specificity; Synaptic Transmission

1994
Influence of flumazenil on the learning-enhancing effect of ambocarb in rats.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: Animals; Behavior, Animal; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Discrimination Learning; Discrimination, Psychological; Flumazenil; Flunitrazepam; Harmine; Learning; Ligands; Male; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A

1994
Anticonvulsant doses of 2-chloro-N6-cyclopentyladenosine, an adenosine A1 receptor agonist, reduce GABAergic transmission in different areas of the mouse brain.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Depression, Chemical; Diazepam; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Mice, Inbred Strains; Purinergic P1 Receptor Antagonists; Receptors, GABA; Receptors, Purinergic P1; Seizures; Sulfur Radioisotopes; Synaptic Transmission; Tritium; Xanthines

1993
Bicuculline-produced regional differences in the modulation of 35S-TBPS binding by GABA, pentobarbital and diazepam in mouse cerebellum and cortex.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Animals; Bicuculline; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Receptors, GABA-A

1993
GABAA receptor function in the gamma-hydroxybutyrate model of generalized absence seizures.
    Neuropharmacology, 1993, Volume: 32, Issue:4

    Topics: Aminocaproates; Animals; Anticonvulsants; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Chlorine; Convulsants; Electroencephalography; Epilepsy, Absence; Flunitrazepam; In Vitro Techniques; Kinetics; Male; Muscimol; Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sodium Oxybate; Synaptosomes; Vigabatrin

1993
3 alpha-hydroxy-5 alpha-pregnan-20-one modulation of solubilized GABA/benzodiazepine receptor complex.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 45, Issue:4

    Topics: Animals; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; Pregnanolone; Radioligand Assay; Rats; Receptors, GABA-A; Solubility

1993
Comparison of interactions of [3H]muscimol, t-butylbicyclophosphoro[35S]thionate, and [3H]flunitrazepam with cloned gamma-aminobutyric acidA receptors of the alpha 1 beta 2 and alpha 1 beta 2 gamma 2 subtypes.
    Molecular pharmacology, 1993, Volume: 43, Issue:5

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cloning, Molecular; Flunitrazepam; Moths; Muscimol; Radioligand Assay; Receptors, GABA-A; Recombinant Proteins; Zinc

1993
Region-specific changes of GABAA receptors by tolerance to and dependence upon pentobarbital.
    European journal of pharmacology, 1993, May-12, Volume: 236, Issue:1

    Topics: Animals; Body Temperature; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Corpus Striatum; Drug Tolerance; Flunitrazepam; Frontal Lobe; In Vitro Techniques; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Substance-Related Disorders; Sulfur Radioisotopes; Synaptic Membranes

1993
The human neuroblastoma cell line, IMR-32 possesses a GABAA receptor lacking the benzodiazepine modulatory site.
    Neuropharmacology, 1993, Volume: 32, Issue:5

    Topics: Animals; Azides; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Chloride Channels; Flunitrazepam; Humans; Kinetics; Membrane Proteins; Neuroblastoma; Radioligand Assay; Rats; Receptors, GABA-A; Tumor Cells, Cultured

1993
Stereospecific actions of the inhalation anesthetic isoflurane at the GABAA receptor complex.
    Brain research, 1993, Jun-25, Volume: 615, Issue:1

    Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flunitrazepam; In Vitro Techniques; Isoflurane; Male; Mice; Receptors, GABA-A; Stereoisomerism; Sulfur Radioisotopes

1993
High-affinity partial agonist imidazo[1,5-a]quinoxaline amides, carbamates, and ureas at the gamma-aminobutyric acid A/benzodiazepine receptor complex.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Animals; Anxiety; Benzodiazepines; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flunitrazepam; GABA Agonists; GABA Antagonists; Molecular Conformation; Molecular Structure; Oxadiazoles; Pentylenetetrazole; Quinoxalines; Rats; Receptors, GABA-A

1996
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
    Biochemical pharmacology, 1996, Jun-14, Volume: 51, Issue:11

    Topics: Anesthetics; Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Triazoles; Tritium

1996
Loreclezole modulates [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding via a distinct site on the GABAA receptor complex.
    European journal of pharmacology, 1996, Apr-04, Volume: 300, Issue:1-2

    Topics: Animals; Anticonvulsants; Benzodiazepinones; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Drug Interactions; Flunitrazepam; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA; Triazoles

1996
Interaction of allosteric ligands with GABAA receptors containing one, two, or three different subunits.
    European journal of pharmacology, 1996, Apr-22, Volume: 301, Issue:1-3

    Topics: Allosteric Site; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Convulsants; Flunitrazepam; GABA Agonists; GABA Modulators; GABA-A Receptor Antagonists; Humans; Kidney; Membranes; Muscimol; Radioligand Assay; Receptors, GABA-A

1996
Antisense oligonucleotide to GABAA receptor gamma 2 subunit induces loss of neurones in rat hippocampus.
    Neuroscience letters, 1995, Dec-29, Volume: 202, Issue:1-2

    Topics: Animals; Base Sequence; Behavior, Animal; Benzodiazepines; Bridged Bicyclo Compounds, Heterocyclic; Cell Count; Convulsants; Flunitrazepam; GABA Agonists; GABA Modulators; Hippocampus; Male; Molecular Sequence Data; Muscimol; Neurons; Oligonucleotides, Antisense; Rats; Rats, Wistar; Receptors, GABA-A; Sulfur Radioisotopes; Tritium

1995
Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:3

    Topics: Animals; Anticonvulsants; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; GABA Modulators; Humans; In Vitro Techniques; Kindling, Neurologic; Mice; Pregnanolone; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Seizures

1997
Pharmacology of skeletal muscle GABA-gated chloride channels in the cockroach Periplaneta americana.
    The Journal of experimental biology, 1997, Volume: 200, Issue:Pt 23

    Topics: Animals; Bicuculline; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Flunitrazepam; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channel Gating; Isonicotinic Acids; Male; Motor Neurons; Muscle, Skeletal; Periplaneta; Picrotoxin; Receptors, GABA; Sesterterpenes

1997
Clathrin-coated vesicles from bovine brain contain uncoupled GABAA receptors.
    Brain research, 1997, Nov-21, Volume: 776, Issue:1-2

    Topics: Allosteric Site; Animals; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cerebral Cortex; Chloride Channels; Clathrin; Coated Vesicles; Convulsants; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Ligands; Pyridazines; Receptors, GABA-A; Sulfur Radioisotopes; Synaptic Membranes; Tritium

1997
Two imidazoquinoxaline ligands for the benzodiazepine site sharing a second low affinity site on rat GABA(A) receptors but with the opposite functionality.
    British journal of pharmacology, 1998, Volume: 123, Issue:8

    Topics: Animals; Anti-Anxiety Agents; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Cloning, Molecular; Electric Stimulation; Electrophysiology; Flunitrazepam; GABA-A Receptor Agonists; Imidazoles; In Vitro Techniques; Ligands; Membrane Potentials; Patch-Clamp Techniques; Quinolines; Quinoxalines; Rats; Receptors, GABA-A

1998
Chronic ethanol administration alters the modulatory effect of 5alpha-pregnan-3alpha-ol-20-one on the binding characteristics of various radioligands of GABAA receptors.
    Brain research, 1998, Sep-14, Volume: 805, Issue:1-2

    Topics: Animals; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebellum; Cerebral Cortex; Ethanol; Flunitrazepam; GABA Agonists; GABA Modulators; Hippocampus; Male; Muscimol; Pregnanolone; Rats; Rats, Sprague-Dawley; Time Factors

1998
Substituted 3beta-phenylethynyl derivatives of 3alpha-hydroxy-5alpha-pregnan-20-one: remarkably potent neuroactive steroid modulators of gamma-aminobutyric acidA receptors.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; GABA Modulators; Humans; Male; Mice; Muscimol; Pregnanolone; Rats; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus

1998
Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites.
    European journal of pharmacology, 1999, Jun-30, Volume: 375, Issue:1-3

    Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; Drug Interactions; Enzyme Inhibitors; Estrus; Female; Finasteride; Flunitrazepam; GABA Modulators; Gestational Age; Hippocampus; Postpartum Period; Pregnancy; Pregnancy, Animal; Pregnanolone; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

1999
Activation of protein kinase C by phorbol dibutyrate modulates GABAA receptor binding in rat brain slices.
    Brain research, 1999, Dec-11, Volume: 850, Issue:1-2

    Topics: Animals; Autoradiography; Brain Chemistry; Bridged Bicyclo Compounds, Heterocyclic; Enzyme Activation; Flunitrazepam; GABA Agonists; GABA Modulators; In Vitro Techniques; Ligands; Muscimol; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Receptors, GABA-A

1999
Synthesis and GABA(A) receptor activity of 6-oxa-analogs of neurosteroids.
    Steroids, 2000, Volume: 65, Issue:6

    Topics: Animals; Antipsychotic Agents; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cholestanones; Flunitrazepam; GABA Modulators; Hydrogen Bonding; Inhibitory Concentration 50; Molecular Structure; Muscimol; Rats; Receptors, GABA-A; Steroids; Structure-Activity Relationship

2000
Heterogeneity of hippocampal GABA(A) receptors: regulation by corticosterone.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Jan-01, Volume: 21, Issue:1

    Topics: Allosteric Regulation; Animals; Autoradiography; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Corticosterone; Dendrites; Desoxycorticosterone; Drug Implants; Flunitrazepam; gamma-Aminobutyric Acid; Hippocampus; Ligands; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2001
Unsulfated and sulfated neurosteroids differentially modulate the binding characteristics of various radioligands of GABA(A) receptors following chronic ethanol administration.
    Neuropharmacology, 2001, Volume: 40, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Central Nervous System Depressants; Cerebellum; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Ethanol; Flunitrazepam; GABA Agonists; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Steroids

2001
High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3-c]quinolin-3-ones.
    Bioorganic & medicinal chemistry, 2003, Nov-17, Volume: 11, Issue:23

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; GABA Modulators; Humans; Ligands; Magnetic Resonance Spectroscopy; Male; Quinolones; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis

2003
Radioligand binding studies of caloporoside and novel congeners with contrasting effects upon [35S] TBPS binding to the mammalian GABA(A) receptor.
    Biochemical pharmacology, 2005, Nov-01, Volume: 70, Issue:9

    Topics: Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Flunitrazepam; gamma-Aminobutyric Acid; Glucosides; Male; Mannose; Muscimol; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Salicylates; Structure-Activity Relationship; Sulfur Radioisotopes

2005
Autoradiographic analysis of GABAA receptors in mu-opioid receptor knockout mice.
    Neurochemical research, 2007, Volume: 32, Issue:11

    Topics: Animals; Autoradiography; Brain; Bridged Bicyclo Compounds, Heterocyclic; Chloride Channels; Down-Regulation; Flunitrazepam; Male; Mice; Mice, Knockout; Muscimol; Receptors, GABA-A; Receptors, Opioid, mu; Tritium; Up-Regulation

2007
Normalization of GABAA receptor specific binding in the substantia nigra reticulata and the prevention of L-dopa-induced dyskinesias in MPTP parkinsonian monkeys.
    Synapse (New York, N.Y.), 2008, Volume: 62, Issue:2

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Autoradiography; Behavior, Animal; Benzoxazoles; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Disease Models, Animal; Dyskinesia, Drug-Induced; Female; Flunitrazepam; GABA Modulators; Isotopes; Levodopa; Macaca fascicularis; Ovariectomy; Parkinsonian Disorders; Piperidines; Protein Binding; Radiography; Receptors, GABA; Substantia Nigra

2008
Effect of synthetic steroids on GABAA receptor binding in rat brain.
    Neuroscience, 2015, Apr-02, Volume: 290

    Topics: Animals; Autoradiography; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Flunitrazepam; GABA-A Receptor Agonists; Hippocampus; Male; Muscimol; Pregnanolone; Protein Binding; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Tritium

2015