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tert-butylbicyclophosphorothionate and alphaxalone

tert-butylbicyclophosphorothionate has been researched along with alphaxalone in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19905 (22.73)18.7374
1990's16 (72.73)18.2507
2000's0 (0.00)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kokka, N; Longoni, B; Olsen, RW; Sapp, DW; Turner, DM; Witte, U1
Callachan, H; Gill, C; Hales, TG; Hill-Venning, C; Lambert, JJ; Peters, JA; Sturgess, NC1
Kokka, N; Olsen, RW; Sapp, DW; Witte, U1
Biggio, G; Concas, A; Maciocco, E; Mascia, MP; Santoro, G1
Biggio, G; Concas, A; Mascia, MP; Sanna, E; Santoro, G; Serra, M1
Olsen, RW; Ransom, RW; Turner, DM; Yang, JS1
Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Santoro, G1
Biggio, G; Ghiani, CA; Maciocco, E; Sanna, E; Serra, M; Tuligi, G1
Banerjee, PK; Brailowsky, S; Olsen, RW; Snead, OC; Tillakaratne, NJ; Tobin, AJ1
Davidoff, RA; Hackman, JC; Holohean, AM; Katz, JL; Valeyev, AY; Wood, PM2
Olsen, RW; Sapp, DW; Srinivasan, S; Tobin, AJ1
Akk, G; Covey, DF; Elias, G; Evers, AS; Krishnan, K; Kudova, E; Li, P; Manion, BD; Mennerick, S; Qian, M; Taylor, A; Zorumski, CF1
Korpi, ER; Lüddens, H; Seeburg, PH1
Cadoni, C; Gee, KW1
Casida, JE; Gee, KW; Lawrence, LJ; Palmer, CJ; Wang, X; Yamamura, HI1
Casida, JE; Cole, LM; Lawrence, LJ1
Casida, JE; Richardson, M; Saederup, E; Squires, RF1
Ramanjaneyulu, R; Ticku, MK1
Ticku, MK; Yu, R1
Gruber, L; Maksay, G; Molnár, P1
Saederup, E; Squires, RF1

Other Studies

22 other study(ies) available for tert-butylbicyclophosphorothionate and alphaxalone

ArticleYear
Regional variation in steroid anesthetic modulation of [35S]TBPS binding to gamma-aminobutyric acidA receptors in rat brain.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2

    Topics: Anesthetics; Animals; Benzodiazepinones; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Pregnanediones; Rats; Receptors, GABA-A

1992
The actions of endogenous and synthetic pregnane steroids on GABAA receptors.
    Advances in biochemical psychopharmacology, 1992, Volume: 47

    Topics: Adrenal Medulla; Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Cells, Cultured; Cloning, Molecular; Electrophysiology; In Vitro Techniques; Membranes; Neurons; Pregnanediones; Pregnanes; Radioligand Assay; Rats; Receptors, GABA-A

1992
Sex differences in sensitivity to pentylenetetrazol but not in GABAA receptor binding.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:2

    Topics: Anesthetics; Animals; Anticonvulsants; Autoradiography; Benzodiazepinones; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Convulsants; Diazepam; Electroshock; Ethanol; Female; Flunitrazepam; Male; Muscimol; Orchiectomy; Ovariectomy; Pentylenetetrazole; Pregnanediones; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Sex Characteristics

1992
The general anesthetic propofol: a biochemical tool to study the function of the GABA-coupled chloride channel.
    Clinical neuropharmacology, 1992, Volume: 15 Suppl 1 Pt A

    Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; gamma-Aminobutyric Acid; Ion Channels; Male; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Inbred Strains

1992
The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex.
    Journal of neurochemistry, 1990, Volume: 55, Issue:6

    Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; gamma-Aminobutyric Acid; Male; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Inbred Strains

1990
Steroid anesthetics and naturally occurring analogs modulate the gamma-aminobutyric acid receptor complex at a site distinct from barbiturates.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3

    Topics: Anesthetics; Animals; Barbiturates; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; In Vitro Techniques; Male; Muscimol; Pregnanediones; Rats; Rats, Inbred Strains; Receptors, GABA-A; Steroids; Structure-Activity Relationship

1989
Effects of propofol, pentobarbital and alphaxalone on t-[35S]butylbicyclophosphorothionate binding in rat cerebral cortex.
    European journal of pharmacology, 1994, Apr-15, Volume: 267, Issue:2

    Topics: Anesthetics; Animals; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; Male; Membranes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes

1994
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain.
    Biochemical pharmacology, 1996, Jun-14, Volume: 51, Issue:11

    Topics: Anesthetics; Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Triazoles; Tritium

1996
Absence seizures decrease steroid modulation of t-[35S]butylbicyclophosphorothionate binding in thalamic relay nuclei.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Action Potentials; Animals; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Epilepsy, Absence; gamma-Aminobutyric Acid; Hydroxybutyrates; Male; Pentobarbital; Pregnanediones; Rats; Rats, Sprague-Dawley; Sulfur Radioisotopes; Thalamic Nuclei

1998
GABA-Induced Cl- current in cultured embryonic human dorsal root ganglion neurons.
    Journal of neurophysiology, 1999, Volume: 82, Issue:1

    Topics: Adult; Baclofen; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chloride Channels; Convulsants; Crotonates; Embryo, Mammalian; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Potassium Channels; Pregnanediones; Receptors, GABA-A; Taurine

1999
Alphaxalone activates a Cl- conductance independent of GABAA receptors in cultured embryonic human dorsal root ganglion neurons.
    Journal of neurophysiology, 1999, Volume: 82, Issue:1

    Topics: Anesthetics; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chloride Channels; Embryo, Mammalian; Ganglia, Spinal; Humans; Ion Channel Gating; Kinetics; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pregnanediones; Receptors, GABA; Receptors, GABA-A; Virulence Factors, Bordetella

1999
Biphasic modulation of GABA(A) receptor binding by steroids suggests functional correlates.
    Neurochemical research, 1999, Volume: 24, Issue:11

    Topics: Androstanes; Anesthetics; Animals; Azasteroids; Baculoviridae; Bicuculline; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cell Membrane; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Pregnanediones; Rats; Receptors, GABA-A; Recombinant Proteins; Spodoptera; Steroids; Sulfur Radioisotopes

1999
Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone.
    Journal of medicinal chemistry, 2014, Jan-09, Volume: 57, Issue:1

    Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; GABA Modulators; HEK293 Cells; Humans; Models, Molecular; Neurotransmitter Agents; Pregnanediones; Pregnanolone; Rats; Receptors, GABA-A; Structure-Activity Relationship; Xenopus laevis

2014
GABAA antagonists reveal binding sites for [35S]TBPS in cerebellar granular cell layer.
    European journal of pharmacology, 1992, Feb-18, Volume: 211, Issue:3

    Topics: Androstanes; Animals; Autoradiography; Azasteroids; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebellar Cortex; Convulsants; GABA Antagonists; GABA-A Receptor Antagonists; Male; Pyridazines; Rats; Rats, Inbred Strains; Sulfur Radioisotopes

1992
Complex interactions between the steroid derivative RU 5135 and the GABAA-receptor complex.
    European journal of pharmacology, 1992, Oct-01, Volume: 227, Issue:2

    Topics: Androstanes; Animals; Azasteroids; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pregnanediol; Pregnanolone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereoisomerism

1992
t-[3H]butylbicycloorthobenzoate: new radioligand probe for the gamma-aminobutyric acid-regulated chloride ionophore.
    Journal of neurochemistry, 1985, Volume: 45, Issue:3

    Topics: Androstanes; Animals; Azasteroids; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Chemical Phenomena; Chemistry; Chlorides; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Ionophores; Kinetics; Male; Rats; Receptors, GABA-A; Temperature

1985
Similar properties of [35S]t-butylbicyclophosphorothionate receptor and coupled components of the GABA receptor-ionophore complex in brains of human, cow, rat, chicken and fish.
    Life sciences, 1984, Oct-22, Volume: 35, Issue:17

    Topics: Androstanes; Animals; Azasteroids; Binding, Competitive; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cattle; Chickens; Convulsants; Female; Fishes; Humans; Ivermectin; Lactones; Male; Middle Aged; Muscimol; Rats; Receptors, GABA-A; Taurine

1984
[35S]t-butylbicyclophosphorothionate binds with high affinity to brain-specific sites coupled to gamma-aminobutyric acid-A and ion recognition sites.
    Molecular pharmacology, 1983, Volume: 23, Issue:2

    Topics: Androstanes; Animals; Azasteroids; Barbiturates; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Bromates; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Rats; Receptors, Cell Surface; Receptors, GABA-A; Temperature; Tissue Distribution

1983
RO5-4864 inhibits the binding of [35S]t-butylbicyclophosphorothionate to rat brain membranes.
    Life sciences, 1984, Feb-13, Volume: 34, Issue:7

    Topics: Androstanes; Animals; Azasteroids; Benzodiazepinones; Bicuculline; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cell Membrane; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; Hippocampus; Male; Picrotoxin; Radioligand Assay; Rats

1984
Chronic neurosteroid treatment produces functional heterologous uncoupling at the gamma-aminobutyric acid type A/benzodiazepine receptor complex in mammalian cortical neurons.
    Molecular pharmacology, 1995, Volume: 47, Issue:3

    Topics: Androstanes; Animals; Azasteroids; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebral Cortex; Chlorides; Chlorine; Convulsants; Drug Interactions; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Mice; Mice, Inbred C57BL; Neurons; Pregnanolone; Radioisotopes; Radioligand Assay; Receptors, GABA-A; Sulfur Radioisotopes; Time Factors; Tritium

1995
Common modes of action of gamma-butyrolactones and pentylenetetrazol on the GABAA receptor-ionophore complex.
    European journal of pharmacology, 1994, Dec-15, Volume: 288, Issue:1

    Topics: 4-Butyrolactone; Androstanes; Animals; Azasteroids; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebral Cortex; Convulsants; Electrophysiology; Flumazenil; GABA Antagonists; Ionophores; Male; Neurons; Patch-Clamp Techniques; Pentylenetetrazole; Prosencephalon; Rats; Rats, Wistar; Receptors, GABA-A; Stereoisomerism; Synaptosomes

1994
Mono N-aryl ethylenediamine and piperazine derivatives are GABAA receptor blockers: implications for psychiatry.
    Neurochemical research, 1993, Volume: 18, Issue:7

    Topics: Androstanes; Animals; Antidepressive Agents; Antipsychotic Agents; Azasteroids; Bicarbonates; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Ethylenediamines; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Piperazines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

1993