Page last updated: 2024-09-03

tert-butyl beta-carboline-3-carboxylate and physostigmine

tert-butyl beta-carboline-3-carboxylate has been researched along with physostigmine in 2 studies

Compound Research Comparison

Studies
(tert-butyl beta-carboline-3-carboxylate)
Trials
(tert-butyl beta-carboline-3-carboxylate)
Recent Studies (post-2010)
(tert-butyl beta-carboline-3-carboxylate)
Studies
(physostigmine)
Trials
(physostigmine)
Recent Studies (post-2010) (physostigmine)
45076,230252331

Protein Interaction Comparison

ProteinTaxonomytert-butyl beta-carboline-3-carboxylate (IC50)physostigmine (IC50)
AcetylcholinesteraseElectrophorus electricus (electric eel)0.1666
AcetylcholinesteraseTetronarce californica (Pacific electric ray)0.3023
CholinesteraseHomo sapiens (human)0.3055
Cytochrome P450 2D6Homo sapiens (human)0.2
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.857
AcetylcholinesteraseMus musculus (house mouse)0.0269
AcetylcholinesteraseHomo sapiens (human)0.0853
Acetylcholinesterase Bos taurus (cattle)0.7197
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.857
Delta-type opioid receptorMus musculus (house mouse)1.1821
AcetylcholinesteraseGallus gallus (chicken)0.02
AcetylcholinesteraseRattus norvegicus (Norway rat)0.0416
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.857
CholinesteraseEquus caballus (horse)0.4081
CholinesteraseMus musculus (house mouse)0.28
Acyl-CoA:cholesterol acyltransferase Oryctolagus cuniculus (rabbit)0.0189
Carboxylic ester hydrolase Rattus norvegicus (Norway rat)0.018
Carboxylic ester hydrolase Equus caballus (horse)1.263

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Karplus, M; So, SS1
Albrecht, RF; Cook, JM; Hagen, TJ; Hoffman, WE; Miletich, DJ1

Other Studies

2 other study(ies) available for tert-butyl beta-carboline-3-carboxylate and physostigmine

ArticleYear
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 2. Applications.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Cholinesterase Inhibitors; Dopamine beta-Hydroxylase; Drug Design; Enzyme Inhibitors; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Molecular Conformation; Molecular Structure; Neural Networks, Computer; Phosphorylases; Receptors, Aryl Hydrocarbon; Static Electricity; Structure-Activity Relationship

1997
Cerebrovascular and cerebral metabolic effects of physostigmine, midazolam, and a benzodiazepine antagonist.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:6

    Topics: Anesthesia, Inhalation; Animals; Benzodiazepines; Blood Pressure; Carbolines; Carbon Dioxide; Cerebrovascular Circulation; Drug Interactions; Halothane; Heart Rate; Hydrogen-Ion Concentration; Injections, Intraperitoneal; Male; Microspheres; Midazolam; Oxygen; Physostigmine; Rats; Rats, Inbred Strains

1986