tert-butoxide--potassium has been researched along with aniline* in 1 studies
1 other study(ies) available for tert-butoxide--potassium and aniline
| Article | Year |
|---|---|
Synthesis of carbazoles via an intramolecular cyclization of 2-(6-substituted 3(Z)-hexen-1,5-diynyl)anilines and their related molecules.
Various 2-(6-substituted 3(Z)-hexen-1,5-diynyl)anilines 1a-g were treated with potassium tert-butoxide or potassium 3-ethylpentanoxide in NMP at 60 degrees C for 2 h to give the corresponding 5-substituted carbazoles 2a-g in 36-65% yields together with indoles 9a-g in 21-40% yields, respectively. Exposing the trifluoroacetamide analogues 10h-k under the same reaction conditions gave the carbazoles 2b-e in 37-57% yields and indoles 9b-e in 15-27% yields. Subsequent cyclizations of acetamide analogues 10a-g gave carbazoles 2a-g in 53-86% yields. Topics: Acetamides; Acetates; Alkenes; Alkynes; Aniline Compounds; Antineoplastic Agents; Butanols; Carbazoles; Chlorides; Cyclization; Fluoroacetates; Indoles; Trifluoroacetic Acid | 2004 |