tert-butanesulfinamide has been researched along with trimethylsilyl-cyanide* in 1 studies
1 other study(ies) available for tert-butanesulfinamide and trimethylsilyl-cyanide
| Article | Year |
|---|---|
Lewis acid promoted diastereoselective addition of TMSCN and TMSCF3 to isatin-derived N-sulfinyl ketimines: synthesis of optically active tetrasubstituted 3-aminooxindoles.
A practical and efficient method for preparation of highly enantiomerically enriched 3-cyano-3-aminooxindoles and 3-trifluoromethyl-3-aminooxindoles with up to 99% optical purity by a Lewis acid promoted diastereoselective Strecker reaction and trifluoromethylation of isatin-derived N-tert-butanesulfinyl ketimines has been developed. This protocol allows direct use of N-free isatin substrates under mild conditions. Topics: Butanes; Catalysis; Cyanides; Hydrocarbons, Fluorinated; Imines; Indoles; Isatin; Lewis Acids; Methylation; Molecular Structure; Nitriles; Silica Gel; Stereoisomerism; Sulfonamides; Trimethylsilyl Compounds | 2014 |