territrem b has been researched along with Dihydrotanshinone I in 3 studies
| Studies (territrem b) | Trials (territrem b) | Recent Studies (post-2010) (territrem b) | Studies (Dihydrotanshinone I) | Trials (Dihydrotanshinone I) | Recent Studies (post-2010) (Dihydrotanshinone I) |
|---|---|---|---|---|---|
| 25 | 0 | 5 | 88 | 0 | 74 |
| Protein | Taxonomy | territrem b (IC50) | Dihydrotanshinone I (IC50) |
|---|---|---|---|
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 3.05 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 0.59 | |
| Acetylcholinesterase | Homo sapiens (human) | 1 | |
| Tyrosine-protein phosphatase non-receptor type 6 | Homo sapiens (human) | 3.67 | |
| Tyrosine-protein phosphatase non-receptor type 11 | Homo sapiens (human) | 3.94 | |
| ELAV-like protein 1 | Homo sapiens (human) | 0.1085 | |
| Hypoxia-inducible factor 1-alpha | Homo sapiens (human) | 2.17 | |
| Endothelial PAS domain-containing protein 1 | Homo sapiens (human) | 2.17 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Rashid, ZF; Beri, V; Cheung, J; Rosenberry, TL; Shiomi, K; Wildman, SA | 1 |
| Cheung, J; Gary, EN; Rosenberry, TL; Shiomi, K | 1 |
| Beri, V; Cheung, J; Rosenberry, TL; Shiomi, K | 1 |
1 review(s) available for territrem b and Dihydrotanshinone I
| Article | Year |
|---|---|
Acetylcholinesterase complexes with the natural product inhibitors dihydrotanshinone I and territrem B: binding site assignment from inhibitor competition and validation through crystal structure determination.
Topics: Acetylcholinesterase; Amino Acid Sequence; Animals; Binding Sites; Biological Products; Cholinesterase Inhibitors; Furans; Humans; Molecular Sequence Data; Phenanthrenes; Pyrans; Quinones | 2014 |
2 other study(ies) available for territrem b and Dihydrotanshinone I
| Article | Year |
|---|---|
The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.
Topics: Acetylcholine; Acetylcholinesterase; Aflatoxin B1; Binding Sites; Binding, Competitive; Catalysis; Catalytic Domain; Cholinesterase Inhibitors; Crystallography, X-Ray; Furans; Humans; Hydrolysis; Kinetics; Models, Chemical; Phenanthrenes; Pyrans; Quinones; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2013 |
Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility.
Topics: | 2013 |