Page last updated: 2024-09-02

territrem b and Dihydrotanshinone I

territrem b has been researched along with Dihydrotanshinone I in 3 studies

Compound Research Comparison

Studies
(territrem b)
Trials
(territrem b)
Recent Studies (post-2010)
(territrem b)
Studies
(Dihydrotanshinone I)
Trials
(Dihydrotanshinone I)
Recent Studies (post-2010) (Dihydrotanshinone I)
250588074

Protein Interaction Comparison

ProteinTaxonomyterritrem b (IC50)Dihydrotanshinone I (IC50)
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus3.05
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.59
AcetylcholinesteraseHomo sapiens (human)1
Tyrosine-protein phosphatase non-receptor type 6Homo sapiens (human)3.67
Tyrosine-protein phosphatase non-receptor type 11Homo sapiens (human)3.94
ELAV-like protein 1Homo sapiens (human)0.1085
Hypoxia-inducible factor 1-alphaHomo sapiens (human)2.17
Endothelial PAS domain-containing protein 1Homo sapiens (human)2.17

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al-Rashid, ZF; Beri, V; Cheung, J; Rosenberry, TL; Shiomi, K; Wildman, SA1
Cheung, J; Gary, EN; Rosenberry, TL; Shiomi, K1
Beri, V; Cheung, J; Rosenberry, TL; Shiomi, K1

Reviews

1 review(s) available for territrem b and Dihydrotanshinone I

ArticleYear
Acetylcholinesterase complexes with the natural product inhibitors dihydrotanshinone I and territrem B: binding site assignment from inhibitor competition and validation through crystal structure determination.
    Journal of molecular neuroscience : MN, 2014, Volume: 53, Issue:3

    Topics: Acetylcholinesterase; Amino Acid Sequence; Animals; Binding Sites; Biological Products; Cholinesterase Inhibitors; Furans; Humans; Molecular Sequence Data; Phenanthrenes; Pyrans; Quinones

2014

Other Studies

2 other study(ies) available for territrem b and Dihydrotanshinone I

ArticleYear
The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.
    Biochemistry, 2013, Oct-22, Volume: 52, Issue:42

    Topics: Acetylcholine; Acetylcholinesterase; Aflatoxin B1; Binding Sites; Binding, Competitive; Catalysis; Catalytic Domain; Cholinesterase Inhibitors; Crystallography, X-Ray; Furans; Humans; Hydrolysis; Kinetics; Models, Chemical; Phenanthrenes; Pyrans; Quinones; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity

2013
Structures of human acetylcholinesterase bound to dihydrotanshinone I and territrem B show peripheral site flexibility.
    ACS medicinal chemistry letters, 2013, Nov-14, Volume: 4, Issue:11

    Topics:

2013