Page last updated: 2024-08-16

terfenadine and theophylline

terfenadine has been researched along with theophylline in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's4 (19.05)18.2507
2000's4 (19.05)29.6817
2010's8 (38.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caron, G; Ermondi, G1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Mio, M; Okamoto, M; Tasaka, K1
Fitzsimmons, WE; Luskin, AT; Luskin, SS; MacLeod, CM2
Advenier, C; Beaumont, D; Brion, N; Naline, E; Pays, M1
Nicholson, AN; Stone, BM1
Ciummo, PE; Katz, NL1
Chand, N; De Vine, CL; Diamantis, W; Harrison, JE; Jakubicki, RG; Nolan, KW; Pillar, J; Rooney, SM; Sofia, RD1
Felstead, S1
Bopp, BA; Kukulka, MJ; Machinist, JM1
Dahlgren, D; Lennernäs, H; Roos, C; Sjögren, E1

Trials

2 trial(s) available for terfenadine and theophylline

ArticleYear
Pharmacokinetic evaluation of the terfenadine-theophylline interaction.
    The Journal of allergy and clinical immunology, 1989, Volume: 83, Issue:2 Pt 1

    Topics: Adult; Benzhydryl Compounds; Drug Administration Schedule; Drug Combinations; Drug Interactions; Follow-Up Studies; Humans; Male; Random Allocation; Terfenadine; Theophylline

1989
Single-dose study of the effect of terfenadine on theophylline absorption and disposition.
    Annals of allergy, 1989, Volume: 62, Issue:3

    Topics: Adult; Benzhydryl Compounds; Clinical Trials as Topic; Drug Interactions; Histamine H1 Antagonists; Humans; Immunoassay; Male; Random Allocation; Terfenadine; Theophylline

1989

Other Studies

19 other study(ies) available for terfenadine and theophylline

ArticleYear
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Intracellular calcium release induced by histamine releasers and its inhibition by some antiallergic drugs.
    Annals of allergy, 1986, Volume: 56, Issue:6

    Topics: Aminoquinolines; Animals; Benzhydryl Compounds; Bucladesine; Calcium; Cromolyn Sodium; Histamine Release; Ketotifen; Male; Mast Cells; Membrane Lipids; p-Methoxy-N-methylphenethylamine; Phenothiazines; Rats; Substance P; Terfenadine; Theophylline

1986
Lack of effect of terfenadine on theophylline pharmacokinetics and metabolism in normal subjects.
    British journal of clinical pharmacology, 1989, Volume: 27, Issue:3

    Topics: Adult; Benzhydryl Compounds; Drug Interactions; Humans; Male; Terfenadine; Theophylline; Time Factors; Uric Acid; Xanthines

1989
Antihistamines: impaired performance and the tendency to sleep.
    European journal of clinical pharmacology, 1986, Volume: 30, Issue:1

    Topics: Adult; Benzhydryl Compounds; Diazepam; Female; Flicker Fusion; Histamine Antagonists; Humans; Psychomotor Performance; Sleep; Terfenadine; Theophylline; Triprolidine; Visual Acuity

1986
Interactions and drug-metabolizing enzymes.
    American pharmacy, 1995, Volume: NS35, Issue:9

    Topics: Adolescent; Adult; Anti-Allergic Agents; Antidepressive Agents, Second-Generation; Antifungal Agents; Binding Sites; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Erythromycin; Female; Fluoxetine; Humans; Isoenzymes; Ketoconazole; Liver; Male; Middle Aged; Pharmaceutical Preparations; Terfenadine; Theophylline; Torsades de Pointes

1995
Allergic bronchial eosinophilia: a therapeutic approach for the selection of potential bronchial anti-inflammatory drugs.
    Allergy, 1993, Volume: 48, Issue:8

    Topics: Albuterol; Allergens; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Eosinophilia; Eosinophils; Guinea Pigs; Male; Methylprednisolone; Ovalbumin; Terfenadine; Theophylline

1993
Azithromycin drug interactions.
    Pathologie-biologie, 1995, Volume: 43, Issue:6

    Topics: Anti-Bacterial Agents; Azithromycin; Carbamazepine; Digoxin; Drug Interactions; Ergotamine; In Vitro Techniques; Methylprednisolone; Prothrombin Time; Terfenadine; Theophylline; Warfarin

1995
In vitro plasma protein binding of zileuton and its N-dehydroxylated metabolite.
    Clinical pharmacokinetics, 1995, Volume: 29 Suppl 2

    Topics: Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; Anticoagulants; Blood Proteins; Chromatography, High Pressure Liquid; Drug Interactions; Female; Hematocrit; Humans; Hydroxylation; Hydroxyurea; Ibuprofen; In Vitro Techniques; Isotope Labeling; Lipoxygenase Inhibitors; Male; Naproxen; Prednisolone; Protein Binding; Salicylates; Stereoisomerism; Terfenadine; Theophylline; Warfarin

1995
Human in vivo regional intestinal permeability: quantitation using site-specific drug absorption data.
    Molecular pharmaceutics, 2015, Jun-01, Volume: 12, Issue:6

    Topics: Budesonide; Colon; Cyclosporine; Fenofibrate; Humans; Intestinal Absorption; Intestinal Mucosa; Lisdexamfetamine Dimesylate; Metoprolol; Nifedipine; Pyrimidines; Ranitidine; Rivastigmine; Sumatriptan; Terfenadine; Theophylline

2015