Page last updated: 2024-08-16

terfenadine and sertraline

terfenadine has been researched along with sertraline in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's4 (30.77)29.6817
2010's7 (53.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cianchetta, G; Cruciani, G; Fravolini, A; Giesing, D; Singleton, RW; Vaz, RJ; Wildgoose, M; Zhang, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Doutheau, A; Fontaine, F; Queneau, Y; Sabbah, M; Soulère, L1
Ekins, S; Williams, AJ; Xu, JJ1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Alderman, J; Greenblatt, DJ; Horst, WD; Preskorn, SH1
Jurima-Romet, M; Neigh, S; Wright, M1
Akamine, Y; Kaneko, S; Niioka, T; Saruwatari, J; Takashima, A; Uno, T; Yasui-Furukori, N1

Trials

1 trial(s) available for terfenadine and sertraline

ArticleYear
Different effects of the selective serotonin reuptake inhibitors fluvoxamine, paroxetine, and sertraline on the pharmacokinetics of fexofenadine in healthy volunteers.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cross-Over Studies; Drug Interactions; Female; Fluvoxamine; Half-Life; Humans; Intestine, Small; Liver; Male; Paroxetine; Selective Serotonin Reuptake Inhibitors; Sertraline; Terfenadine; Young Adult

2012

Other Studies

12 other study(ies) available for terfenadine and sertraline

ArticleYear
A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR.
    Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Fluoresceins; Fluorescent Dyes; Humans; Models, Molecular; Multivariate Analysis; Permeability; Quantitative Structure-Activity Relationship

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
LuxR-dependent quorum sensing: computer aided discovery of new inhibitors structurally unrelated to N-acylhomoserine lactones.
    Bioorganic & medicinal chemistry letters, 2010, Aug-01, Volume: 20, Issue:15

    Topics: 4-Butyrolactone; Analgesics; Binding Sites; Computer Simulation; Drug Evaluation, Preclinical; Imidazoles; Quorum Sensing; Repressor Proteins; Small Molecule Libraries; Trans-Activators

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Sertraline does not inhibit cytochrome P450 3A-mediated drug metabolism in vivo.
    Psychopharmacology bulletin, 1997, Volume: 33, Issue:4

    Topics: 1-Naphthylamine; Adolescent; Adult; Alprazolam; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Humans; Male; Middle Aged; Oxidoreductases, N-Demethylating; Selective Serotonin Reuptake Inhibitors; Sertraline; Substrate Specificity; Terfenadine

1997
Terfenadine-antidepressant interactions: an in vitro inhibition study using human liver microsomes.
    British journal of clinical pharmacology, 1998, Volume: 45, Issue:3

    Topics: Alkylation; Antidepressive Agents, Second-Generation; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Fluoxetine; Histamine H1 Antagonists; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Piperazines; Sertraline; Terfenadine; Triazoles

1998