Page last updated: 2024-08-16

terfenadine and rifampin

terfenadine has been researched along with rifampin in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (4.76)	18.2507
2000's	7 (33.33)	29.6817
2010's	12 (57.14)	24.3611
2020's	1 (4.76)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Kulkarni, P; Medapi, B; Medishetti, R; Renuka, J; Saxena, S; Sridevi, JP; Sriram, D; Yogeeswari, P	1
Abutaleb, NS; Alhashimi, M; Kassab, AE; Mayhoub, AS; Mohamed, KO; Seleem, MN; Shahin, IG; Taher, AT	1
Jurima-Romet, M; Li, AP	1
Bruce, MA; Haehner-Daniels, BD; Hall, SD; Hamman, MA	1
Asghar, A; Gorski, JC; Haehner-Daniels, B; Hall, SD	1
Addison, T; Jiang, X; Maleki, S; Naidong, W; Shou, WZ	1
Burggraaff, JE; de Waart, DR; Elferink, RP; Kenworthy, KE; Schinkel, AH; van de Steeg, E; van der Kruijssen, CM; Wagenaar, E	1
Akamine, Y; Fukizawa, S; Ikejiri, K; Kanamitsu, K; Kusuhara, H; Miura, M; Sugiyama, Y; Uno, T; Yasui-Furukori, N; Yokochi, M; Yoshida, K	1
Akamine, Y; Ieiri, I; Miura, M; Uno, T; Yasui-Furukori, N	1
Nezasa, K; Ogawa, K; Shimizu, R; Takai, N; Tanaka, Y; Watanabe, A; Watari, R; Yamaguchi, Y	1
Bharate, SS; Vishwakarma, RA	1

Reviews

1 review(s) available for terfenadine and rifampin

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000

Trials

3 trial(s) available for terfenadine and rifampin

Article	Year
The effect of rifampin administration on the disposition of fexofenadine. Clinical pharmacology and therapeutics, 2001, Volume: 69, Issue:3 Topics: Administration, Oral; Adult; Aged; Aging; Analysis of Variance; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Drug Interactions; Enzyme Inhibitors; Female; Half-Life; Histamine H1 Antagonists; Humans; Male; Metabolic Clearance Rate; Rifampin; Sex Characteristics; Terfenadine	2001
Effect of coadministration of single and multiple doses of rifampicin on the pharmacokinetics of fexofenadine enantiomers in healthy subjects. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Adult; Aged; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Reference Values; Rifampin; Terfenadine; Young Adult	2013
Effects of multiple-dose rifampicin 450 mg on the pharmacokinetics of fexofenadine enantiomers in Japanese volunteers. Journal of clinical pharmacy and therapeutics, 2015, Volume: 40, Issue:1 Topics: Anti-Allergic Agents; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP2B6 Inducers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Healthy Volunteers; Humans; Japan; Rifampin; Terfenadine	2015

Other Studies

17 other study(ies) available for terfenadine and rifampin

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Design and synthesis of novel quinoline-aminopiperidine hybrid analogues as Mycobacterium tuberculosis DNA gyraseB inhibitors. Bioorganic & medicinal chemistry, 2015, May-01, Volume: 23, Issue:9 Topics: Animals; Anti-Bacterial Agents; DNA Gyrase; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium smegmatis; Mycobacterium tuberculosis; Piperidines; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors; Zebrafish	2015
Evaluation of N-phenyl-2-aminothiazoles for treatment of multi-drug resistant and intracellular Staphylococcus aureus infections. European journal of medicinal chemistry, 2020, Sep-15, Volume: 202 Topics: Animals; Anti-Bacterial Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Molecular Structure; Staphylococcal Infections; Structure-Activity Relationship; Thiazoles	2020
Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin. Cell biology and toxicology, 1997, Volume: 13, Issue:4-5 Topics: Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Humans; Lidocaine; Liver; Mixed Function Oxygenases; Rifampin; Steroid Hydroxylases; Terfenadine	1997
Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:1 Topics: Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Female; Humans; Lymphocytes; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Terfenadine	2002
Liquid chromatography/tandem mass spectrometric bioanalysis using normal-phase columns with aqueous/organic mobile phases - a novel approach of eliminating evaporation and reconstitution steps in 96-well SPE. Rapid communications in mass spectrometry : RCM, 2002, Volume: 16, Issue:20 Topics: Adrenergic beta-Antagonists; Bronchodilator Agents; Chromatography, Liquid; Ephedrine; Histamine H1 Antagonists; Humans; Leprostatic Agents; Metoprolol; Pharmaceutical Preparations; Quality Control; Reproducibility of Results; Rifampin; Robotics; Solvents; Spectrometry, Mass, Electrospray Ionization; Terfenadine	2002
Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs. The Journal of clinical investigation, 2010, Volume: 120, Issue:8 Topics: Animals; Bile Acids and Salts; Bilirubin; Female; Liver; Liver-Specific Organic Anion Transporter 1; Male; Methotrexate; Mice; Mice, Knockout; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Rifampin; Terfenadine	2010
Using improved serial blood sampling method of mice to study pharmacokinetics and drug-drug interaction. Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:3 Topics: Administration, Intravenous; Administration, Oral; Animals; Antipyrine; Biological Availability; Blood Specimen Collection; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Drug Monitoring; Ibuprofen; Male; Mice, Inbred C57BL; Models, Animal; Organic Anion Transporters; Pravastatin; Reproducibility of Results; Rifampin; Tail; Terfenadine; Triazoles; Veins	2015
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7 Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics	2015