Page last updated: 2024-08-16

terfenadine and pyrilamine

terfenadine has been researched along with pyrilamine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's7 (33.33)18.2507
2000's6 (28.57)29.6817
2010's2 (9.52)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Achterrath, U; Duflos, M; Emig, P; Fouchard, F; Günther, E; Kutscher, B; Le Baut, G; Menciu, C; Nickel, B; Schmidt, J; Szelenyi, I1
Strassburg, CP; Tukey, RH1
Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD1
Caron, G; Ermondi, G1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Coyle, AJ; Lefort, J; Vargaftig, BB1
Basilico, C; Caselli, GF; Dini, S; Giani, R; Lavezzo, A1
Foxwell, MH; Johnson, DN; Kilpatrick, BF; Leonard, CA; Nolan, JC; Proakis, AG; Stephens, DJ; Yanni, JM1
Fleisch, JH; Haisch, KD; Rinkema, LE; Whitesitt, CA1
Baltes, E; De Vos, C; Gobert, J; Maleux, MR1
Obel, AO1
Martin, JS; Wiech, NL1
Imano, K; Ishii, K; Karasawa, T; Nakamura, H; Seto, Y; Takeyama, K; Yakuo, I1
Barak, V; Fabian, I; Geller-Bernstein, C; Handzel, ZT; Mor, S; Nagler, A1
Guinosso, PJ; Jurkiewicz, NK; Lynch, JJ; Salata, JJ; Stupienski, RF; Wallace, AA1
Díaz-Trelles, R; Fernández-Sánchez, MT; Novelli, A; Puia, G1
Inagaki, N; Kanke, T; Matsumoto, J; Nagai, H; Nagao, M; Takizawa, T; Timmerman, H; Tohma, T; Wada, Y; Zhang, MQ1
Makita, S; Sakairi, T; Shakuto, S; Suzuki, K; Wajima, T; Yaguchi, M; Yoshida, Y1
Chess-Williams, R; Moro, C; Stromberga, Z1
Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H1

Reviews

1 review(s) available for terfenadine and pyrilamine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

20 other study(ies) available for terfenadine and pyrilamine

ArticleYear
New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.
    Journal of medicinal chemistry, 1999, Feb-25, Volume: 42, Issue:4

    Topics: Acetylcholine; Animals; Anti-Allergic Agents; Bronchoalveolar Lavage; Capillary Permeability; Carbachol; Eosinophilia; Guinea Pigs; Histamine Release; Hypersensitivity; In Vitro Techniques; Indoleacetic Acids; Interleukin-4; Interleukin-5; Male; Mast Cells; Muscle Contraction; Muscle, Smooth; Peritoneal Cavity; Polyunsaturated Alkamides; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Rhinitis, Allergic, Perennial; Structure-Activity Relationship; Trachea

1999
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
The effect of cetirizine on antigen-dependent leucopenia in the guinea-pig.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: Animals; Benzeneacetamides; Benzhydryl Compounds; Blood Platelets; Cetirizine; Female; Guinea Pigs; Histamine H1 Antagonists; Hydroxamic Acids; Hydroxyzine; In Vitro Techniques; Leukocyte Count; Leukopenia; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Pyrilamine; Terfenadine

1991
Antihistaminic/antiallergic activity of 2-dialkylaminoalkylthio(oxy)-1-substituted benzimidazoles: evaluation "in vitro" and "in vivo".
    Agents and actions, 1990, Volume: 30, Issue:1-2

    Topics: Animals; Benzhydryl Compounds; Benzimidazoles; Blood-Brain Barrier; Brain; Clemastine; Guinea Pigs; Histamine Antagonists; Histamine Release; Hypersensitivity; Imidazoles; In Vitro Techniques; Mice; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Pyrilamine; Radioligand Assay; Rats; Sulfides; Terfenadine

1990
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
    Agents and actions, 1989, Volume: 28, Issue:1-2

    Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cats; Chlorpheniramine; Diphenhydramine; Electroencephalography; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Kinetics; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Oxazepines; Piperazines; Promethazine; Pyrilamine; Terfenadine; Yohimbine

1989
Pharmacologic analysis of LY188695 (KB-2413), 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate, a potent histamine1 receptor antagonist.
    Agents and actions, 1987, Volume: 20, Issue:1-2

    Topics: Animals; Benzhydryl Compounds; Benzimidazoles; Bronchial Provocation Tests; Chlorpheniramine; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Lung; Male; Muscle, Smooth; Promethazine; Pyrilamine; Terfenadine; Triprolidine

1987
Inhibition of histamine and allergen skin wheal by cetirizine in four animal species.
    Annals of allergy, 1987, Volume: 59, Issue:4

    Topics: Allergens; Animals; Benzhydryl Compounds; Cetirizine; Clemastine; Dogs; Female; Guinea Pigs; Histamine; Histamine Antagonists; Hydroxyzine; Hypersensitivity, Immediate; Male; Mice; Mice, Inbred Strains; Pyrilamine; Rats; Rats, Inbred Strains; Skin; Species Specificity; Terfenadine

1987
Practical therapeutics: the use of histamine receptor antagonists in contemporary times.
    East African medical journal, 1984, Volume: 61, Issue:7

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Cimetidine; Conjunctivitis, Allergic; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Pyrilamine; Rhinitis, Allergic, Seasonal; Terfenadine

1984
Absence of an effect of terfenadine on guinea pig brain histamine H1-receptors in vivo determined by receptor binding techniques.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9a

    Topics: Animals; Benzhydryl Compounds; Binding, Competitive; Brain; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine; Receptors, Histamine H1; Terfenadine; Time Factors

1982
[Pharmacological study of ebastine, a novel histamine H1-receptor antagonist].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1994, Volume: 103, Issue:3

    Topics: Administration, Oral; Animals; Butyrophenones; Disease Models, Animal; Dose-Response Relationship, Drug; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity; In Vitro Techniques; Male; Phenothiazines; Piperidines; Pyrilamine; Rats; Rats, Wistar; Terfenadine

1994
Histamine enhances granulocyte-macrophage colony-stimulating factor and interleukin-6 production by human peripheral blood mononuclear cells.
    Journal of leukocyte biology, 1995, Volume: 58, Issue:4

    Topics: Antibodies; Cell Adhesion; Cells, Cultured; Cimetidine; Enzyme-Linked Immunosorbent Assay; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Interleukin-3; Interleukin-6; Kinetics; Leukocytes, Mononuclear; Pyrilamine; Radioimmunoassay; Ranitidine; Stem Cells; Stimulation, Chemical; Terfenadine

1995
Cardiac electrophysiological actions of the histamine H1-receptor antagonists astemizole and terfenadine compared with chlorpheniramine and pyrilamine.
    Circulation research, 1995, Volume: 76, Issue:1

    Topics: Action Potentials; Animals; Astemizole; Chlorpheniramine; Dose-Response Relationship, Drug; Electrocardiography; Guinea Pigs; Heart; In Vitro Techniques; Potassium Channels; Pyrilamine; Refractory Period, Electrophysiological; Terfenadine

1995
Terfenadine prevents NMDA receptor-dependent and -independent toxicity following sodium channel activation.
    Brain research, 1999, Sep-25, Volume: 842, Issue:2

    Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Glutamic Acid; Neurons; Pyrilamine; Rats; Receptors, N-Methyl-D-Aspartate; Saxitoxin; Sodium Channels; Terfenadine; Tetrodotoxin; Veratridine

1999
VUF-K-8788, a periphery-selective histamine H1 antagonist with anti-pruritic activities.
    Japanese journal of pharmacology, 2001, Volume: 86, Issue:1

    Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Benzimidazoles; Capillary Permeability; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Ketotifen; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Muscle Contraction; Passive Cutaneous Anaphylaxis; Peripheral Nervous System; Piperazines; Pruritus; Pyrilamine; Rats; Rats, Wistar; Terfenadine; Thiazines

2001
Effects of fexofenadine hydrochloride in a guinea pig model of antigen-induced rhinitis.
    Pharmacology, 2005, Volume: 75, Issue:2

    Topics: Airway Resistance; Animals; Anti-Allergic Agents; Area Under Curve; Carbazoles; Disease Models, Animal; Guinea Pigs; Indoles; Leukotrienes; Male; Ovalbumin; Phenylcarbamates; Pyrilamine; Rhinitis; Sulfonamides; Terfenadine; Thromboxanes; Tosyl Compounds

2005
Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors.
    Scientific reports, 2019, 03-07, Volume: 9, Issue:1

    Topics: Animals; Cyproheptadine; Histamine; Histamine Agonists; Histamine Antagonists; Mucous Membrane; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Swine; Terfenadine; Urinary Bladder; Urothelium

2019
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:5

    Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine

2021