Page last updated: 2024-08-16

terfenadine and promethazine

terfenadine has been researched along with promethazine in 22 studies

Research

Studies (22)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (18.18)	18.7374
1990's	2 (9.09)	18.2507
2000's	7 (31.82)	29.6817
2010's	9 (40.91)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Bechtel, WD; Fügner, A; Kuhn, FJ; Mierau, J	1
Foxwell, MH; Johnson, DN; Kilpatrick, BF; Leonard, CA; Nolan, JC; Proakis, AG; Stephens, DJ; Yanni, JM	1
Nicholson, AN	1
Fleisch, JH; Haisch, KD; Rinkema, LE; Whitesitt, CA	1
Cuss, FM; Del Prado, M; Egan, RW; Hey, JA; Kreutner, W; Lin, CC; Sherwood, J	1
Fairweather, DB; Hindmarch, I; Shamsi, Z; Stanley, N	1
Mills, SL; Nicholson, AN; Stone, BM; Turner, C	1
Hindmarch, I; Kimber, S; Shamsi, Z	1
Hindmarch, I; Ridout, F	1
Bai, F; Li, XW; Lü, JY; Niu, SC; Wu, BW; Zhang, L; Zhang, XP	1
Isaji, A; Ishikawa, K; Kamei, H; Nabeshima, T; Noda, Y; Senzaki, K; Sugiura, K; Tomita, Y; Yamada, K	1
Furutani, K; Inanobe, A; Kurachi, Y; Ohno, Y; Yamakawa, Y	1
Anoopkumar-Dukie, S; Grant, GD; Kavanagh, JJ; Naicker, P	1
Kawada, T	1
Hasselstrøm, SB; Kristensen, DM; Munkboel, CH; Styrishave, B	1

Reviews

1 review(s) available for terfenadine and promethazine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000

Trials

6 trial(s) available for terfenadine and promethazine

Article	Year
A double-blind, placebo-controlled investigation of the effects of fexofenadine, loratadine and promethazine on cognitive and psychomotor function. British journal of clinical pharmacology, 1999, Volume: 48, Issue:2 Topics: Adult; Cognition; Cross-Over Studies; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Loratadine; Male; Middle Aged; Promethazine; Psychomotor Performance; Reaction Time; Terfenadine; Wrist	1999
Antihistamines and aircrew: usefulness of fexofenadine. Aviation, space, and environmental medicine, 2000, Volume: 71, Issue:1 Topics: Adult; Aerospace Medicine; Attention; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Promethazine; Sleep Stages; Terfenadine	2000
An evaluation of the effects of high-dose fexofenadine on the central nervous system: a double-blind, placebo-controlled study in healthy volunteers. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:1 Topics: Adult; Central Nervous System; Cognition; Cross-Over Studies; Differential Threshold; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Male; Middle Aged; Placebos; Promethazine; Psychomotor Performance; Reaction Time; Reference Values; Terfenadine	2002
The effects of acute doses of fexofenadine, promethazine, and placebo on cognitive and psychomotor function in healthy Japanese volunteers. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:4 Topics: Adult; Asian People; Biotransformation; Blood-Brain Barrier; Cognition; Cross-Over Studies; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Japan; Male; Middle Aged; Promethazine; Psychomotor Performance; Reaction Time; Terfenadine	2003
Effects of single therapeutic doses of promethazine, fexofenadine and olopatadine on psychomotor function and histamine-induced wheal- and flare-responses: a randomized double-blind, placebo-controlled study in healthy volunteers. Archives of dermatological research, 2012, Volume: 304, Issue:4 Topics: Adolescent; Dibenzoxepins; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Olopatadine Hydrochloride; Promethazine; Pruritus; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Terfenadine; Urticaria; Young Adult	2012
The effects of antihistamines with varying anticholinergic properties on voluntary and involuntary movement. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2013, Volume: 124, Issue:9 Topics: Adult; Cholinergic Antagonists; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Promethazine; Reaction Time; Sleep Stages; Terfenadine; Tremor; Young Adult	2013

Other Studies

15 other study(ies) available for terfenadine and promethazine

Article	Year
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
In vitro and in vivo studies of the non-sedating antihistamine epinastine. Arzneimittel-Forschung, 1988, Volume: 38, Issue:10 Topics: Animals; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cats; Dibenzazepines; Dogs; Female; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Ileum; Imidazoles; In Vitro Techniques; Ketotifen; Male; Promethazine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Sleep; Terfenadine; Wakefulness	1988
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine. Agents and actions, 1989, Volume: 28, Issue:1-2 Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cats; Chlorpheniramine; Diphenhydramine; Electroencephalography; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Kinetics; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Oxazepines; Piperazines; Promethazine; Pyrilamine; Terfenadine; Yohimbine	1989
Central effects of H1 and H2 antihistamines. Aviation, space, and environmental medicine, 1985, Volume: 56, Issue:4 Topics: Aerospace Medicine; Benzhydryl Compounds; Central Nervous System; Chlorpheniramine; Cimetidine; Clemastine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Phenothiazines; Promethazine; Psychomotor Performance; Ranitidine; Sleep Stages; Structure-Activity Relationship; Terfenadine; Visual Acuity; Visual Perception	1985
Pharmacologic analysis of LY188695 (KB-2413), 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole difumarate, a potent histamine1 receptor antagonist. Agents and actions, 1987, Volume: 20, Issue:1-2 Topics: Animals; Benzhydryl Compounds; Benzimidazoles; Bronchial Provocation Tests; Chlorpheniramine; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Lung; Male; Muscle, Smooth; Promethazine; Pyrilamine; Terfenadine; Triprolidine	1987
Antihistamine activity, central nervous system and cardiovascular profiles of histamine H1 antagonists: comparative studies with loratadine, terfenadine and sedating antihistamines in guinea-pigs. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1995, Volume: 25, Issue:10 Topics: Animals; Cardiovascular System; Central Nervous System; Diphenhydramine; Electrocardiography; Electroencephalography; Guinea Pigs; Histamine H1 Antagonists; Hypnotics and Sedatives; Loratadine; Male; Promethazine; Quinidine; Terfenadine	1995
Differences of promethazine and terfenadine on ion channels in guinea pig ventricular myocytes. Chinese medical journal, 2006, Jun-05, Volume: 119, Issue:11 Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Heart Ventricles; Ion Channels; Male; Myocytes, Cardiac; Promethazine; Terfenadine; Time Factors	2006
Pharmacophore modeling for hERG channel facilitation. Biochemical and biophysical research communications, 2012, Feb-03, Volume: 418, Issue:1 Topics: Animals; Atenolol; Chlorpheniramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoxetine; Haloperidol; Humans; Hydrophobic and Hydrophilic Interactions; Imipramine; Metoprolol; Nortriptyline; Potassium Channel Blockers; Promethazine; Propranolol; Quantitative Structure-Activity Relationship; Sotalol; Terfenadine; Verapamil; Xenopus laevis	2012
The effect of antihistamines on behavioral activity by actigraphy. Archives of dermatological research, 2014, Volume: 306, Issue:2 Topics: Dibenzoxepins; Female; Histamine H1 Antagonists; Humans; Male; Promethazine; Psychomotor Performance; Terfenadine; Urticaria	2014
Effects of antihistamines on the H295R steroidogenesis - Autocrine up-regulation following 3β-HSD inhibition. Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 48 Topics: 3-Hydroxysteroid Dehydrogenases; Autocrine Communication; Cell Line; Cell Survival; Cetirizine; Enzyme Inhibitors; Gene Expression Regulation; Histamine Antagonists; Histamine H1 Antagonists; Humans; Promethazine; Real-Time Polymerase Chain Reaction; Steroids; Terfenadine; Up-Regulation	2018