Page last updated: 2024-08-16

terfenadine and hypericum

terfenadine has been researched along with hypericum in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stein, CM1
Hall, SD; Hamman, MA; Huang, SM; Lesko, LJ; Wang, Z1
Dresser, GK; Kim, RB; Schwarz, UI; Wilkinson, GR1
Antal, EJ; Arakawa, T; Gordi, T; Hong, C; Knuth, DW; Nickens, DJ; Polasek, EC; Sharma, A; Tan, LH; Teillol-Foo, M; Xie, R1
Milne, RW; Ngo, SN; Turkanovic, J1
Gerber, JP; Milne, RW; Turkanovic, J; Ward, MB1

Trials

3 trial(s) available for terfenadine and hypericum

ArticleYear
Effect of St John's wort on the pharmacokinetics of fexofenadine.
    Clinical pharmacology and therapeutics, 2002, Volume: 71, Issue:6

    Topics: Adult; Anti-Allergic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Hypericum; Male; Reference Values; Terfenadine

2002
Coordinate induction of both cytochrome P4503A and MDR1 by St John's wort in healthy subjects.
    Clinical pharmacology and therapeutics, 2003, Volume: 73, Issue:1

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Cross-Over Studies; Cyclosporine; Cytochrome P-450 CYP3A; Drug Administration Schedule; Enzyme Induction; Female; Gene Expression Regulation; Genes, MDR; Humans; Hypericum; Intestinal Mucosa; Liver; Male; Midazolam; Middle Aged; Oxidoreductases, N-Demethylating; Plant Preparations; Reference Values; Terfenadine

2003
CYP3A and P-glycoprotein activity induction with St. John's Wort in healthy volunteers from 6 ethnic populations.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:3

    Topics: Adult; Asian People; ATP Binding Cassette Transporter, Subfamily B, Member 1; Black or African American; Cytochrome P-450 CYP3A; Female; Genotype; Herb-Drug Interactions; Hispanic or Latino; Humans; Hypericum; Male; Midazolam; Middle Aged; Phenotype; Plant Preparations; Terfenadine; White People

2005

Other Studies

3 other study(ies) available for terfenadine and hypericum

ArticleYear
Are herbal products dietary supplements or drugs? An important question for public safety.
    Clinical pharmacology and therapeutics, 2002, Volume: 71, Issue:6

    Topics: Anti-Allergic Agents; Cardiovascular System; Ephedra; Histamine H1 Antagonists; Humans; Hypericum; Pharmacokinetics; Plant Extracts; Terfenadine; United States; United States Food and Drug Administration

2002
Effect of St John's wort on the disposition of fexofenadine in the isolated perfused rat liver.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:8

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Cyclosporine; Drug Interactions; Hepatocytes; Histamine H1 Antagonists, Non-Sedating; Hypericum; Liver; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Terfenadine

2009
Effect of Garlic, Gingko, and St. John's Wort Extracts on the Pharmacokinetics of Fexofenadine: A Mechanistic Study.
    Drug metabolism and disposition: the biological fate of chemicals, 2017, Volume: 45, Issue:5

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Interactions; Garlic; Ginkgo biloba; Hypericum; Injections, Intravenous; Intestinal Mucosa; Liver; Male; Organic Anion Transporters, Sodium-Independent; Perfusion; Plant Extracts; Rats; Substrate Specificity; Terfenadine; Tissue Distribution

2017