terfenadine has been researched along with histamine in 131 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (22.90) | 18.7374 |
| 1990's | 43 (32.82) | 18.2507 |
| 2000's | 37 (28.24) | 29.6817 |
| 2010's | 21 (16.03) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Ghys, L; Mühlethaler, K; Rihoux, JP; Wüthrich, B | 1 |
| Naclerio, RM | 1 |
| Hill, S; Lever, LR; Marks, R; Rosenberg, R; Thompson, D | 1 |
| Finnerty, JP; Harvey, A; Holgate, ST | 1 |
| Fuller, RW; Studham, J | 1 |
| Barlas, A; Gemicioğlu, B; Gürsoy, M; Koldaş, L; Ozüner, Z; Umut, S; Yildirim, N | 1 |
| Holgate, ST; Phillips, GD; Polosa, R; Rajakulasingam, K | 1 |
| Lush, M; Marks, R; Newcombe, RG; Shall, L | 1 |
| Baber, NS; Gill, D; James, I; Jordan, S; Sciberras, DG | 1 |
| Chapman, ID; Hoshiko, K; Morley, J | 1 |
| Hamid, M; Holgate, ST; Rafferty, P | 1 |
| Freidhoff, L; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Proud, D | 1 |
| Chapman, RW; Egan, RW; Kreutner, W; Mauser, PJ | 1 |
| Campa, PP; Dawodu, AA; Evangelista, E; Lanti, M; Marino, B; Monti, F; Puddu, PE; Pulvirenti, G; Schiariti, M; Terracciano, CM | 1 |
| Crowley, JP; Miller, SD; Pritchard, D | 1 |
| Boehm, S; Doyle, WJ; Fireman, P; Skoner, DP | 1 |
| Agrawal, DK; Bewtra, AK; Hopp, RJ; Townley, RG | 1 |
| Holgate, ST; Lai, CK; Phillips, GD; Polosa, R | 1 |
| Dinh Xuan, AT; Lockhart, A; Marsac, J; Regnard, J; Rey, J; Similowski, T | 1 |
| Druce, HM | 1 |
| McMillan, JL; Simons, FE; Simons, KJ | 1 |
| Rafferty, P | 1 |
| Adamus, WS; Kuthan, H; Schilling, JC | 1 |
| Bergström, R; Hägermark, O; Wahlgren, CF | 1 |
| Crossman, DC; Fuller, RW | 1 |
| Belcher, NG; Lee, TH; O'Hickey, SP; Rees, PJ | 1 |
| Djukanovic, R; Finnerty, JP; Holgate, ST | 1 |
| Holgate, ST; Phillips, GD | 1 |
| Lahti, A; Työlahti, H | 1 |
| Adams, J; Posner, J; Rolan, PE | 1 |
| Foxwell, MH; Johnson, DN; Kilpatrick, BF; Leonard, CA; Nolan, JC; Proakis, AG; Stephens, DJ; Yanni, JM | 1 |
| Finnerty, JP; Holgate, ST; Wilmot, C | 1 |
| Rihoux, JP; Van Neste, DJ | 1 |
| Ryan, WM | 1 |
| Dollery, CT; Fuller, RW; Newman, CM; Pixley, FJ; Warren, JB | 1 |
| Araujo, OE; Flowers, FP; Nieves, CH | 1 |
| Holgate, ST; Rafferty, P | 1 |
| Beasley, R; Holgate, S; Rafferty, P; Southgate, P | 1 |
| Humphreys, F; Shuster, S | 1 |
| Marks, R; Shall, L | 1 |
| Beasley, R; Holgate, ST; Phillips, GD; Rafferty, P | 1 |
| Curzen, N; Holgate, ST; Rafferty, P | 1 |
| Gaffey, MJ; Hayden, FG; Kaiser, DL | 1 |
| Chernick, V; Montgomery, M; Pasterkamp, H; Poynter, A; Wiebicke, W | 1 |
| Bloom, M; Dupont, P; Pechadre, JC; Rihoux, JP; Trolese, JF; Vernay, D | 1 |
| Simons, FE; Simons, KJ; Watson, WT | 1 |
| Rihoux, JP; Van Neste, D | 1 |
| Baltes, E; De Vos, C; Gobert, J; Maleux, MR | 1 |
| Gendreau-Reid, L; Simons, FE; Simons, KJ | 1 |
| Diffey, BL; Farr, PM; Humphreys, F | 1 |
| Mizuno, A; Nakashima, M; Sogabe, K; Takiguchi, Y; Uematsu, T | 1 |
| Bödeker, RH; Paul, E; Pfeffer, M | 1 |
| Marks, R; Newcombe, RG; Shall, L | 1 |
| Barnes, PJ; Braude, S; Coe, C; Royston, D | 1 |
| Barak, V; Fabian, I; Geller-Bernstein, C; Handzel, ZT; Mor, S; Nagler, A | 1 |
| Bischoff, SC; de Weck, AL; Derer, T; Takafuji, S | 1 |
| Colin, JN; Dry, J; Gillotin, C; Leynadier, F; Murrieta, M; Steru, D | 1 |
| Crimi, N; Mistretta, A; Oliveri, R; Palemo, F; Polosa, R; Prosperini, G; Pulvirenti, G | 1 |
| Gupta, U; Mehta, VL; Tekur, U | 1 |
| Bódis, J; Hanf, V; Papenfuss, F; Schwarz, H; Tinneberg, HR; Török, A | 1 |
| Baroody, FM; Naclerio, RM; Wagenmann, M | 1 |
| Cartier, A; Ghezzo, H; L'Archevêque, J; Labrecque, M; Malo, JL; Trudeau, C | 1 |
| Horio, T; Miyauchi, H | 1 |
| Agarwal, MK; Chhabra, SK; Jhamb, S; Singh, P | 1 |
| Archer, CB; Brooks, J; Burton, JL; Sansom, JE | 1 |
| Vere, DW | 1 |
| Goldenring, JR; Kidd, M; Lawton, GP; Miu, K; Modlin, IM; Pasikhov, D; Powers, RE; Soroka, CJ; Tang, LH; Zhu, Z | 1 |
| Akpolat, N; Celebioglu, B; Ercan, S; Erdem, K; Kahraman, S; Kanbak, M | 1 |
| Koëter, GH; Postma, DS; Rutgers, SR; van der Mark, TW | 1 |
| Cho, CH; Chow, JY; Ma, L | 1 |
| Archer, CB; Greaves, MW; Kavanagh, GM; Sabroe, RA | 1 |
| Inagaki, N; Kawasaki, H; Musoh, K; Nagai, H; Nagao, M; Nakamura, N | 1 |
| Danielson, L; DeVos, C; Grant, JA; Rihoux, JP | 1 |
| Abdelaziz, MM; Devalia, JL; Khair, OA | 1 |
| Irman-Florjanc, T | 1 |
| Díaz-Trelles, R; Fernández-Sánchez, MT; Marini, A; Novelli, A; Vega, JA | 1 |
| Gu, X; Johnston, L; Simons, FE; Simons, KJ | 1 |
| Duvernelle, C; Frossard, N; Melac, M; Pauli, G; Purohit, A | 1 |
| Inagaki, N; Kanke, T; Matsumoto, J; Nagai, H; Nagao, M; Takizawa, T; Timmerman, H; Tohma, T; Wada, Y; Zhang, MQ | 1 |
| Ashida, Y; Kohno, S; Matsumoto, T; Mizutani, N; Nabe, T; Sasaki, K; Yamasaki, M | 1 |
| DeVos, C; Grant, JA; Moulaert, B; Riethuisen, JM | 1 |
| Inoue, T; Katoh, N; Kishimoto, S; Matsunaga, K | 1 |
| Itoh, M; Iwabuchi, K; Mochizuki, H; Sakurada, Y; Tashiro, M; Watanabe, T; Yanai, K | 1 |
| Ghorab, M; Ghorab, MM; Hammady, TH; Nada, AH | 1 |
| Grzelewska-Rzymowska, I; Kroczyńska-Bednarek, J; Pietrzkowicz, M | 1 |
| Hagan, LL; More, DR; Napoli, DC | 1 |
| Boyce, M; Carey, W; Luria, X; Warrington, S | 1 |
| Díaz-Trelles, R; Fernández-Sánchez, MT; Novelli, A | 1 |
| Csaba, G; Inczefi-Gonda, A; Kovács, P; Pállinger, E | 1 |
| Aragane, Y; Kawada, A; Maeda, A; Matsushita, K; Tezuka, T; Yamazaki, F | 1 |
| Jackson, CM; Lee, DK; Lipworth, BJ | 1 |
| Iizuka, H; Ishida-Yamamoto, A; Takahashi, H | 1 |
| Deslandes, B; Frossard, N; N'Gom, AS; Pauli, G; Purohit, A | 1 |
| Fu, YL; He, SH; Xie, H | 1 |
| Andoh, T; Kuraishi, Y; Lee, JB; Nojima, H; Ui, H | 1 |
| Aleman, PA; Antón-Fos, GM; Duart, MJ; Galvez, J; García-Domenech, R; Martín-Algarra, RV | 1 |
| Berisa, A; Corcóstegui, R; Innerárity, A; Labeaga, L; Orjales, A | 1 |
| Burtin, B; Hohlfeld, JM; Krug, N; Larbig, M; Luettig, B; Martin, L; Stamm, H | 1 |
| Kamei, J; Takahashi, Y | 1 |
| Kruszewski, J; Kłos, K; Sułek, K | 1 |
| Kruszewski, J; Kruszewski, R; Kłos, K; Sułek, K | 1 |
| Azzolina, A; Cervello, M; Lampiasi, N; Montalto, G | 1 |
| Hayashi, S; Itabashi, T; Kamei, J; Kawai, K; Takahashi, Y | 1 |
| Casale, TB; Jones, DH; Romero, FA | 1 |
| Andoh, T; Kuraishi, Y; Lee, JB; Tsujii, K | 1 |
| Ikezawa, Z; Inomata, N; Tatewaki, S | 1 |
| dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A | 1 |
| Andoh, T; Kuraishi, Y; Saito, A | 1 |
| Pyzlak, M; Szczesniak, A; Szewczyk, G; Szukiewicz, D | 1 |
| Ewert, R; Gläser, S; Gustavus, B; Hanf, G; Koch, B; Kunkel, G; Noga, O; Schäper, C | 1 |
| Alonso-Tejerina, E; Asumendi, A; Blaya, B; Boyano, MD; Burgos-Bretones, J; Jangi, SM; Nicolau-Galmés, F; Ortega-Martínez, I; Pérez-Yarza, G | 1 |
| Andoh, T; Hattori, M; Kuraishi, Y; Tanaka, K; Tayama, M; Yamamoto, T; Zhang, Q | 1 |
| Asano, K; Furuta, A; Hirano, K; Shoji, N; Suzaki, H | 1 |
| Behrens, CJ; Caliskan, G; Fano, S; Heinemann, U | 1 |
| Fukuoka, M; Ikoma, A; Kabashima, K; Miyachi, Y; Tanizaki, H | 1 |
| Andoh, T; Honma, A; Kitazawa, K; Kuraishi, Y; Sakai, K; Urashima, M | 1 |
| Church, MK; Maurer, M | 1 |
| Church, MK; Maurer, M; Schoepke, N | 1 |
| He, S; Mo, YZ; Wei, JF; Wei, XL; Yang, H | 1 |
| Kabashima, K; Miyachi, Y; Nakahigashi, K; Tanizaki, H | 1 |
| Cieślińska, A; Jarmołowska, B; Karolina Kordulewska, N; Kostyra, E; Matysiewicz, M | 1 |
| Dreyer, HC; Ely, MR; Halliwill, JR; Hocker, AD; Luttrell, MJ; Mangum, JE; Romero, SA; Sieck, DC; Struck, AJ; Turnbull, DW | 1 |
| Cieślińska, A; Fiedorowicz, E; Jarmołowska, B; Kordulewska, NK; Kostyra, E | 1 |
| Cieślińska, A; Fiedorowicz, E; Kordulewska, NK; Kostyra, E; Matysiewicz, M; Sienkiewicz-Szłapka, E | 1 |
| Akatsu, C; Fukui, H; Hishinuma, S; Kosaka, K; Shoji, M; Uesawa, Y | 1 |
| Chess-Williams, R; Moro, C; Stromberga, Z | 1 |
| Chwała, B; Cieślińska, A; Fiedorowicz, E; Jarmołowska, B; Kordulewska, NK; Kostyra, E; Moszyńska, M | 1 |
4 review(s) available for terfenadine and histamine
| Article | Year |
|---|---|
Antihistamines in the treatment of clinical asthma.
Topics: Animals; Asthma; Benzhydryl Compounds; Cetirizine; Dose-Response Relationship, Drug; Forced Expiratory Volume; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Delayed; Peak Expiratory Flow Rate; Phthalazines; Terfenadine | 1990 |
Antihistamines.
Topics: Animals; Astemizole; Benzhydryl Compounds; Benzimidazoles; Child; Child, Preschool; Cimetidine; Drug Synergism; Guanidines; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Infant; Infant, Newborn; Kinetics; Pyrimidinones; Ranitidine; Terfenadine | 1986 |
Histamine and histamine receptor antagonists in cancer biology.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Melanoma; Receptors, Histamine; Terfenadine | 2010 |
H(1)-antihistamines and urticaria: how can we predict the best drug for our patient?
Topics: Anti-Allergic Agents; Cetirizine; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Predictive Value of Tests; Skin Tests; Terfenadine; Urticaria | 2012 |
69 trial(s) available for terfenadine and histamine
| Article | Year |
|---|---|
The skin as a target organ for the investigation of antiallergic drugs: comparison between cetirizine and terfenadine.
Topics: Adolescent; Adult; Antigens; Cetirizine; Dermatitis; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Male; Middle Aged; Skin Tests; Terfenadine | 1992 |
Inhibition of mediator release during the early reaction to antigen.
Topics: Albumins; Antigens; Cetirizine; Esterases; Histamine; Humans; Kinins; Loratadine; Nasal Mucosa; Nasal Provocation Tests; Terfenadine; Tosylarginine Methyl Ester | 1992 |
Effects of cetirizine, loratadine and terfenadine on histamine weal and flare reactions.
Topics: Administration, Oral; Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Erythema; Female; Histamine; Histamine Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Random Allocation; Skin; Terfenadine | 1992 |
The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma.
Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Female; Flurbiprofen; Forced Expiratory Volume; Histamine; Humans; Hyperventilation; Male; Middle Aged; Placebos; Terfenadine | 1992 |
The effect of oral terfenadine on the sensitivity of the cough reflex in normal volunteers.
Topics: Administration, Oral; Adult; Capsaicin; Cough; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Humans; Random Allocation; Reflex; Terfenadine | 1992 |
The effect of inhaled ipratropium bromide alone and in combination with oral terfenadine on bronchoconstriction provoked by adenosine 5'-monophosphate and histamine in asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Adult; Asthma; Benzhydryl Compounds; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; Drug Therapy, Combination; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Ipratropium; Male; Terfenadine | 1991 |
Dose-response relationship between objective measures of histamine-induced weals and dose of terfenadine.
Topics: Adult; Benzhydryl Compounds; Blister; Dose-Response Relationship, Drug; Double-Blind Method; Erythema; Female; Histamine; Histamine H1 Antagonists; Humans; Injections, Intradermal; Male; Skin; Terfenadine; Ultrasonography | 1991 |
The role of histamine in the acute inflammatory responses to intradermal platelet activating factor.
Topics: Benzhydryl Compounds; Double-Blind Method; Drug Hypersensitivity; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Male; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Terfenadine | 1991 |
The inhibitory effect of terfenadine and flurbiprofen on early and late-phase bronchoconstriction following allergen challenge in atopic asthma.
Topics: Adolescent; Adult; Allergens; Asthma; Benzhydryl Compounds; Bronchial Provocation Tests; Female; Flurbiprofen; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Male; Terfenadine | 1990 |
Terfenadine, an H1 antihistamine, inhibits histamine release in vivo in the human.
Topics: Allergens; Benzhydryl Compounds; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Nasal Cavity; Nasal Provocation Tests; Premedication; Rhinitis, Allergic, Seasonal; Terfenadine; Therapeutic Irrigation | 1990 |
Effect of terfenadine on nasal, eustachian tube, and pulmonary function after provocative intranasal histamine challenge.
Topics: Administration, Intranasal; Administration, Oral; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Eustachian Tube; Female; Histamine; Humans; Lung; Male; Middle Aged; Nasal Provocation Tests; Nose; Rhinitis; Terfenadine | 1991 |
Terfenadine effect on the bronchoconstriction, dermal response, and leukopenia induced by platelet-activating factor.
Topics: Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Histamine; Humans; Leukopenia; Male; Platelet Activating Factor; Skin Tests; Terfenadine; Time Factors | 1991 |
Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma.
Topics: Adult; Asthma; Benzhydryl Compounds; Bradykinin; Bronchial Provocation Tests; Female; Flurbiprofen; Histamine; Histamine H1 Antagonists; Humans; Male; Placebos; Terfenadine | 1990 |
Effects of SK&F 104353, a leukotriene receptor antagonist, on the bronchial responses to histamine in subjects with asthma: a comparative study with terfenadine.
Topics: Adult; Asthma; Benzhydryl Compounds; Blood Pressure; Bronchi; Clinical Trials as Topic; Dicarboxylic Acids; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Heart Rate; Histamine; Histamine H1 Antagonists; Humans; Male; SRS-A; Terfenadine | 1990 |
The effects of an H1-receptor antagonist, terfenadine, on histamine-induced microcirculatory changes and vasopermeability in nasal mucosa.
Topics: Adult; Benzhydryl Compounds; Capillary Permeability; Histamine; Histamine H1 Antagonists; Humans; Microcirculation; Middle Aged; Nasal Mucosa; Terfenadine | 1990 |
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria | 1990 |
Antihistaminic activity and side effect profile of epinastine and terfenadine in healthy volunteers.
Topics: Administration, Oral; Adult; Affect; Benzhydryl Compounds; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists; Humans; Imidazoles; Male; Middle Aged; Psychometrics; Reaction Time; Terfenadine | 1990 |
The antipruritic effect of a sedative and a non-sedative antihistamine in atopic dermatitis.
Topics: Adolescent; Adult; Benzhydryl Compounds; Clemastine; Dermatitis, Atopic; Double-Blind Method; Female; Histamine; Humans; Hypnotics and Sedatives; Male; Pruritus; Pyrrolidines; Randomized Controlled Trials as Topic; Terfenadine | 1990 |
Bradykinin induced wheal and flare is not mediated by histamine release or cyclooxygenase products.
Topics: Adult; Aspirin; Benzhydryl Compounds; Bradykinin; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Male; Prostaglandin-Endoperoxide Synthases; Skin Tests; Terfenadine | 1988 |
Role of histamine release in hypertonic saline induced bronchoconstriction.
Topics: Adult; Asthma; Benzhydryl Compounds; Bronchi; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Male; Middle Aged; Saline Solution, Hypertonic; Terfenadine | 1989 |
Wheal-and-flare responses to intradermally injected adenosine 5'-monophosphate, hypertonic saline, and histamine: comparison of atopic and nonatopic subjects.
Topics: Adenosine Monophosphate; Benzhydryl Compounds; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Double-Blind Method; Drug Hypersensitivity; Histamine; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Random Allocation; Skin; Skin Tests; Sodium Chloride; Terfenadine | 1989 |
The effect of oral terfenadine alone and in combination with flurbiprofen on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate in nonatopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Constriction, Pathologic; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Female; Flurbiprofen; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Propionates; Terfenadine | 1989 |
Comparison of the onset of H1-antagonism with acrivastine and terfenadine by histamine bronchial challenge in volunteers.
Topics: Adult; Aerosols; Benzhydryl Compounds; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Lung; Male; Pyridines; Receptors, Histamine H1; Terfenadine; Triprolidine; Vital Capacity | 1989 |
Inhibition of hypertonic saline-induced bronchoconstriction by terfenadine and flurbiprofen. Evidence for the predominant role of histamine.
Topics: Adult; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flurbiprofen; Histamine; Histamine H1 Antagonists; Humans; Male; Propionates; Random Allocation; Saline Solution, Hypertonic; Sodium Chloride; Terfenadine | 1989 |
Quantitative time course study of the skin response to histamine and the effect of H1 blockers. A 3-week crossover double-blind comparative trial of cetirizine and terfenadine.
Topics: Adult; Benzhydryl Compounds; Blood Flow Velocity; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Intradermal Tests; Lasers; Randomized Controlled Trials as Topic; Regional Blood Flow; Skin; Terfenadine | 1989 |
Evaluation of inhibition of wheal response to histamine by multiple doses of terfenadine.
Topics: Adolescent; Adult; Benzhydryl Compounds; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Male; Middle Aged; Terfenadine | 1989 |
The importance of bradykinin and histamine in the skin response to antigen.
Topics: Adult; Animals; Antigens; Benzhydryl Compounds; Bradykinin; Dermatitis, Contact; Enalapril; Female; Histamine; Humans; Male; Mites; Pollen; Skin; Skin Physiological Phenomena; Terfenadine | 1988 |
Terfenadine (Seldane) is a potent and selective histamine H1 receptor antagonist in asthmatic airways.
Topics: Adult; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Male; Methacholine Chloride; Methacholine Compounds; Terfenadine; Time Factors | 1987 |
The role of histamine in allergen and adenosine-induced bronchoconstriction.
Topics: Adenosine Monophosphate; Allergens; Astemizole; Benzhydryl Compounds; Benzimidazoles; Bronchial Provocation Tests; Bronchial Spasm; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Terfenadine | 1987 |
Non-invasive instrumental techniques to detect terfenadine and temelastine induced suppression of histamine weals in man.
Topics: Adolescent; Adult; Benzhydryl Compounds; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Pyrimidinones; Random Allocation; Regional Blood Flow; Skin; Skin Tests; Terfenadine | 1987 |
Effects of a cyclo-oxygenase inhibitor, flurbiprofen, and an H1 histamine receptor antagonist, terfenadine, alone and in combination on allergen induced immediate bronchoconstriction in man.
Topics: Adult; Allergens; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Drug Combinations; Flurbiprofen; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Methacholine Compounds; Propionates; Terfenadine | 1987 |
Ineffectiveness of oral terfenadine in natural colds: evidence against histamine as a mediator of common cold symptoms.
Topics: Adult; Benzhydryl Compounds; Common Cold; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Random Allocation; Rhinitis; Terfenadine | 1988 |
Comparison of the central and peripheral effects of cetirizine and terfenadine.
Topics: Adult; Benzhydryl Compounds; Cetirizine; Electroencephalography; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Terfenadine; Time Factors; Urticaria | 1988 |
Inhibition of the cutaneous response to histamine by H1-blocking agents. Quantitative evaluation of microvascular changes in the skin after histamine challenge and a comparison of the effects of a single intake of cetirizine and terfenadine.
Topics: Adult; Benzhydryl Compounds; Cetirizine; Dermatitis; Double-Blind Method; Erythema; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Injections, Intradermal; Lasers; Male; Microcirculation; Random Allocation; Regional Blood Flow; Rheology; Skin; Terfenadine | 1988 |
Comparison of the suppressive effect of astemizole, terfenadine, and hydroxyzine on histamine-induced wheals and flares in humans.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Dose-Response Relationship, Immunologic; Double-Blind Method; Female; Histamine; Humans; Hydroxyzine; Hypersensitivity, Immediate; Immunosuppressive Agents; Male; Skin Tests; Terfenadine | 1986 |
A quantitative study of the effect of terfenadine on cutaneous erythema induced by UVB and UVC radiation.
Topics: Adult; Animals; Benzhydryl Compounds; Dose-Response Relationship, Radiation; Erythema; Female; Histamine; Humans; Male; Radiation Injuries, Experimental; Terfenadine; Ultraviolet Rays | 1986 |
Application of thermography to the evaluation of the histamine skin test in man.
Topics: Adult; Benzhydryl Compounds; Dose-Response Relationship, Drug; Histamine; Humans; Male; Middle Aged; Skin Tests; Terfenadine; Thermography | 1987 |
Effect of terfenadine and ranitidine on histamine and suxamethonium wheals.
Topics: Adolescent; Adult; Benzhydryl Compounds; Double-Blind Method; Drug Therapy, Combination; Female; Histamine; Humans; Male; Middle Aged; Random Allocation; Ranitidine; Skin; Succinylcholine; Terfenadine; Urticaria | 1988 |
Assessment of the duration of action of terfenadine on histamine induced weals.
Topics: Adult; Benzhydryl Compounds; Double-Blind Method; Female; Histamine; Humans; Male; Middle Aged; Random Allocation; Terfenadine; Urticaria | 1988 |
Histamine increases lung permeability by an H2-receptor mechanism.
Topics: Adult; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Double-Blind Method; Epithelium; Histamine; Histamine H1 Antagonists; Humans; Lung; Male; Permeability; Ranitidine; Receptors, Histamine; Receptors, Histamine H2; Terfenadine | 1984 |
The effect of terfenadine on the immediate and late-phase reactions mediated by immunoglobulin E.
Topics: Administration, Oral; Allergens; Antibodies, Anti-Idiotypic; Basophils; Candida albicans; Complement C5a; Double-Blind Method; Eosinophils; Histamine; Histamine Release; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Immunoglobulin E; Interleukin-3; N-Formylmethionine Leucyl-Phenylalanine; Poaceae; Skin Tests; Terfenadine; Thermography; Time Factors | 1993 |
Effects of acrivastine and terfenadine on skin reactivity to histamine.
Topics: Drug Hypersensitivity; Histamine; Histamine H1 Antagonists; Humans; Pruritus; Skin; Skin Tests; Terfenadine; Triprolidine | 1994 |
Effect of oral terfenadine on bronchoconstrictor response to inhaled neurokinin A and histamine in asthmatic subjects.
Topics: Administration, Oral; Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Double-Blind Method; Female; Histamine; Humans; Male; Neurokinin A; Terfenadine | 1993 |
Pharmacodynamic bioequivalence: evaluation of different brands of terfenadine hydrochloride.
Topics: Adult; Aged; Double-Blind Method; Histamine; Humans; Hypersensitivity, Immediate; Middle Aged; Terfenadine; Therapeutic Equivalency | 1993 |
Duration of effect of loratadine and terfenadine administered once a day for one week on cutaneous and inhaled reactivity to histamine.
Topics: Administration, Inhalation; Adult; Aged; Asthma; Bronchoconstriction; Dose-Response Relationship, Drug; Drug Interactions; Female; Forced Expiratory Volume; Histamine; Humans; Loratadine; Male; Middle Aged; Single-Blind Method; Skin; Terfenadine; Time Factors; Vital Capacity | 1993 |
Effects of H1- and H2-antihistamines on platelet-activating factor and bradykinin-induced inflammatory responses in human skin.
Topics: Administration, Oral; Bradykinin; Cimetidine; Codeine; Double-Blind Method; Doxepin; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Platelet Activating Factor; Skin; Terfenadine; Urticaria | 1996 |
Actions of terfenadine and cimetidine on histamine wheal formation.
Topics: Adult; Cimetidine; Drug Combinations; Female; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Middle Aged; Terfenadine; Urticaria | 1995 |
Prophylactic administration of histamine 1 and/or histamine 2 receptor blockers in the prevention of heparin- and protamine-related haemodynamic effects.
Topics: Administration, Oral; Adult; Anticoagulants; Blood Pressure; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Central Venous Pressure; Diastole; Female; Hemodynamics; Heparin; Heparin Antagonists; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Middle Aged; Protamines; Ranitidine; Systole; Terfenadine | 1996 |
Short-term treatment with budesonide does not improve hyperresponsiveness to adenosine 5'-monophosphate in COPD.
Topics: Adenosine Monophosphate; Administration, Inhalation; Anti-Inflammatory Agents; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Bronchodilator Agents; Budesonide; Cholinergic Antagonists; Female; Forced Expiratory Volume; Glucocorticoids; Histamine; Histamine H1 Antagonists; Humans; Interleukin-8; Ipratropium; Leukocyte Count; Longitudinal Studies; Lung Diseases, Obstructive; Male; Methacholine Chloride; Middle Aged; Neutrophils; Placebos; Smoking; Terfenadine; Time Factors | 1998 |
The intradermal effects of the H3 receptor agonist R alpha methylhistamine in human skin.
Topics: Adult; Dose-Response Relationship, Drug; Female; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Intradermal Tests; Male; Methylhistamines; Skin; Terfenadine | 1998 |
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria | 1999 |
Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast.
Topics: Acetates; Adult; Allergens; Cyclopropanes; Depression, Chemical; Dermatitis, Allergic Contact; Drug Therapy, Combination; Female; Histamine; Humans; Injections; Leukotriene D4; Male; Middle Aged; Quinolines; Sulfides; Terfenadine; Time Factors | 2001 |
Twenty-four hours of activity of cetirizine and fexofenadine in the skin.
Topics: Adolescent; Adult; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Double-Blind Method; Drug Evaluation; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Rhinitis; Skin; Skin Tests; Terfenadine; Time Factors | 2001 |
A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.
Topics: Adult; Benzimidazoles; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Piperidines; Terfenadine; Treatment Outcome; Urticaria | 2002 |
Roles of histamine in regulation of arousal and cognition: functional neuroimaging of histamine H1 receptors in human brain.
Topics: Adult; Arousal; Brain; Brain Chemistry; Cetirizine; Cognition; Cross-Over Studies; Discrimination, Psychological; Double-Blind Method; Doxepin; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Psychomotor Performance; Radiopharmaceuticals; Reaction Time; Receptors, Histamine H1; Sleep Stages; Terfenadine; Tomography, Emission-Computed | 2002 |
Comparative study of some additives for the improvement of terfenadine performance.
Topics: Adult; Area Under Curve; Cyclodextrins; Excipients; Female; Histamine; Histamine H1 Antagonists; Humans; Lactose; Male; Middle Aged; Polyethylene Glycols; Skin Tests; Solubility; Terfenadine; Urea | 2002 |
Herbal supplements and skin testing: the lack of effect of commonly used herbal supplements on histamine skin prick testing.
Topics: Cross-Over Studies; Double-Blind Method; Gastrointestinal Diseases; Histamine; Histamine H1 Antagonists; Humans; Plant Preparations; Skin; Skin Tests; Terfenadine; Time Factors | 2003 |
Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.
Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Piperidines; Skin Tests; Terfenadine | 2002 |
The effects of butterbur on the histamine and allergen cutaneous response.
Topics: Acetates; Adult; Anti-Inflammatory Agents; Cross-Over Studies; Cyclopropanes; Dermatitis, Atopic; Double-Blind Method; Female; Histamine; Humans; Male; Petasites; Phytotherapy; Quinolines; Skin Tests; Sulfides; Terfenadine | 2004 |
Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance.
Topics: Adult; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Dibenzoxepins; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Iontophoresis; Male; Olopatadine Hydrochloride; Piperidines; Psychomotor Performance; Pyridines; Sleep Stages; Terfenadine | 2004 |
Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction.
Topics: Adolescent; Adult; Cetirizine; Cross-Over Studies; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Skin Tests; Terfenadine; Urticaria | 2004 |
Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine.
Topics: Adolescent; Adult; Cetirizine; Cross-Over Studies; Double-Blind Method; Face; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Nasal Provocation Tests; Nose; Piperazines; Skin Temperature; Terfenadine; Thermography | 2006 |
[Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].
Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Placebos; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2006 |
[The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].
Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Regional Blood Flow; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2006 |
Time-dependent inhibition of histamine-induced cutaneous responses by oral and intramuscular diphenhydramine and oral fexofenadine.
Topics: Administration, Oral; Adolescent; Adult; Child; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity, Immediate; Injections, Intramuscular; Male; Middle Aged; Skin Tests; Terfenadine; Time Factors; Treatment Outcome | 2008 |
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2009 |
The inhibition by levocetirizine and fexofenadine of the histamine-induced wheal and flare response in healthy Caucasian and Japanese volunteers.
Topics: Adult; Asian People; Cetirizine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Germany; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Japan; Male; Pruritus; Skin; Terfenadine; Time Factors; Treatment Outcome; Urticaria; White People; Young Adult | 2013 |
Comparison of the efficacy of fexofenadine 120 and 240 mg/day on chronic idiopathic urticaria and histamine-induced skin responses in Japanese populations.
Topics: Adult; Chronic Disease; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Iontophoresis; Male; Pilot Projects; Pruritus; Terfenadine; Urticaria | 2013 |
Evidence of a broad histamine footprint on the human exercise transcriptome.
Topics: Adult; Exercise; Female; Hemodynamics; Histamine; Histamine Antagonists; Histamine H1 Antagonists, Non-Sedating; Histamine H2 Antagonists; Humans; Knee; Male; Muscle, Skeletal; Ranitidine; Receptors, Histamine H1; Receptors, Histamine H2; Terfenadine; Transcriptome; Young Adult | 2016 |
58 other study(ies) available for terfenadine and histamine
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Venous blood histamine levels and effect of terfenadine in patients with bronchial hyperreactivity.
Topics: Adult; Bronchial Hyperreactivity; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Humans; Male; Maximal Midexpiratory Flow Rate; Methacholine Chloride; Terfenadine; Vital Capacity | 1992 |
Histamine(H1) antagonists and airway hyperreactivity in the guinea-pig.
Topics: Airway Resistance; Animals; Bronchoconstriction; Guinea Pigs; Histamine; Histamine H1 Antagonists; Injections, Intravenous; Male; Platelet Activating Factor; Respiratory Hypersensitivity; Terfenadine | 1991 |
Selective inhibition of peripheral histamine responses by loratadine and terfenadine.
Topics: Animals; Benzhydryl Compounds; Bronchi; Cyproheptadine; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine Release; Injections, Intravenous; Injections, Intraventricular; Loratadine; Lung; Lung Compliance; Male; Methacholine Compounds; Terfenadine | 1990 |
[The prevention of an excitation-conduction block during acute myocardial ischemia: is there a role for prostacyclin or for histamine?].
Topics: Acute Disease; Animals; Antihypertensive Agents; Coronary Disease; Dimethyl Sulfoxide; Diuretics; Drug Evaluation, Preclinical; Epoprostenol; Female; Guinea Pigs; Heart Block; Histamine; Histamine Release; Indomethacin; Pyridines; Terfenadine | 1991 |
Blood histamine levels following graded cold challenge in atypical acquired cold urticaria.
Topics: Adult; Cold Temperature; Female; Histamine; Humans; Terfenadine; Time Factors; Urticaria | 1992 |
Start and end of the effects of terfenadine and astemizole on histamine-induced wheals in human skin.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Skin; Skin Tests; Terfenadine; Time Factors | 1989 |
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cats; Chlorpheniramine; Diphenhydramine; Electroencephalography; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Kinetics; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Oxazepines; Piperazines; Promethazine; Pyrilamine; Terfenadine; Yohimbine | 1989 |
The effect of nedocromil on weal reactions in human skin.
Topics: Adult; Animals; Antigens; Benzhydryl Compounds; Dermatitis, Contact; Female; Histamine; Histamine H1 Antagonists; Humans; Iontophoresis; Male; Middle Aged; Mites; Nedocromil; p-Methoxy-N-methylphenethylamine; Quinolines; Terfenadine | 1987 |
Effect of oral terfenadine on the bronchoconstrictor response to inhaled histamine and adenosine 5'-monophosphate in non-atopic asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Adult; Aged; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Terfenadine | 1987 |
Effect of terfenadine on the response to exercise and cold air in asthma.
Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Cold Temperature; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Physical Exertion; Terfenadine | 1988 |
Lack of subsensitivity to terfenadine during long-term terfenadine treatment.
Topics: Adult; Benzhydryl Compounds; Drug Administration Schedule; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Patient Compliance; Skin Tests; Terfenadine; Time Factors | 1988 |
Inhibition of histamine and allergen skin wheal by cetirizine in four animal species.
Topics: Allergens; Animals; Benzhydryl Compounds; Cetirizine; Clemastine; Dogs; Female; Guinea Pigs; Histamine; Histamine Antagonists; Hydroxyzine; Hypersensitivity, Immediate; Male; Mice; Mice, Inbred Strains; Pyrilamine; Rats; Rats, Inbred Strains; Skin; Species Specificity; Terfenadine | 1987 |
Histamine enhances granulocyte-macrophage colony-stimulating factor and interleukin-6 production by human peripheral blood mononuclear cells.
Topics: Antibodies; Cell Adhesion; Cells, Cultured; Cimetidine; Enzyme-Linked Immunosorbent Assay; Granulocyte-Macrophage Colony-Stimulating Factor; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Interleukin-3; Interleukin-6; Kinetics; Leukocytes, Mononuclear; Pyrilamine; Radioimmunoassay; Ranitidine; Stem Cells; Stimulation, Chemical; Terfenadine | 1995 |
The effect of histamine on progesterone and estradiol secretion of human granulosa cells in serum-free culture.
Topics: Adult; Cells, Cultured; Cimetidine; Culture Media; Dose-Response Relationship, Drug; Estradiol; Female; Fertilization in Vitro; Follicular Fluid; Granulosa Cells; Histamine; Humans; Progesterone; Terfenadine | 1993 |
Comparison of the secretory response of the nasal mucosa to methacholine and histamine.
Topics: Adult; Atropine; Diphenhydramine; Dose-Response Relationship, Drug; Female; Histamine; Humans; Kinetics; Lidocaine; Male; Methacholine Chloride; Nasal Mucosa; Receptors, Cholinergic; Receptors, Histamine H1; Reflex; Tachyphylaxis; Terfenadine | 1993 |
Detection of action, inhibition and augmentation spectra in solar urticaria.
Topics: Anaphylaxis; Anti-Allergic Agents; Betamethasone; Cyclizine; Erythema; Female; Glucocorticoids; Histamine; Histamine H1 Antagonists; Humans; Light; Middle Aged; Molecular Weight; Photosensitizing Agents; Phthalazines; Radiation Dosage; Skin; Spectrophotometry; Spectrophotometry, Ultraviolet; Sunlight; Terfenadine; Ultrafiltration; Ultraviolet Rays; Urticaria | 1995 |
Duration of inhibitory effect of terfenadine on histamine-induced skin wheals.
Topics: Adult; Dose-Response Relationship, Immunologic; Drug Administration Schedule; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Male; Middle Aged; Skin Tests; Terfenadine | 1996 |
Evidence for a regulatory role for histamine in gastric enterochromaffin-like cell proliferation induced by hypergastrinemia.
Topics: Animals; Cell Division; Chromogranins; DNA; Enterochromaffin Cells; Female; Gastric Mucosa; Gastrins; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Hyperplasia; In Vitro Techniques; Male; Muridae; Terfenadine; Triazoles | 1996 |
Involvement of free radicals and histamine in the potentiating action of cigarette smoke exposure on ethanol-induced gastric mucosal damage in rats.
Topics: Animals; Disease Models, Animal; Ethanol; Free Radicals; Gastric Mucosa; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Male; Peptic Ulcer; Peroxidase; Ranitidine; Rats; Rats, Sprague-Dawley; Smoking; Superoxide Dismutase; Terfenadine; Xanthine Oxidase | 1998 |
Participation of histamine H1 and H2 receptors in passive cutaneous anaphylaxis-induced scratching behavior in ICR mice.
Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Capillary Permeability; Cetirizine; Drug Interactions; Famotidine; Female; Free Radical Scavengers; Histamine; Histamine H2 Antagonists; Mice; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Ranitidine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Serotonin; Terfenadine; Time Factors | 1999 |
The potential of active metabolites of antihistamines in the management of allergic disease.
Topics: Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Cetirizine; Chymases; Eosinophils; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity; Intercellular Adhesion Molecule-1; Interleukin-3; Interleukin-8; Loratadine; Mast Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Prostaglandin D2; Pyridines; Recombinant Fusion Proteins; Recombinant Proteins; Serine Endopeptidases; Terfenadine; Time Factors; Tryptases | 2000 |
Kinetics of injected histamine in cat plasma after antihistamine prophylaxis.
Topics: Animals; Cats; Cimetidine; Ethylenediamines; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Kinetics; Male; Terfenadine | 2000 |
Antihistamine terfenadine potentiates NMDA receptor-mediated calcium influx, oxygen radical formation, and neuronal death.
Topics: Animals; Biological Transport; Calcium; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Chlorpheniramine; Cyclic GMP; Dizocilpine Maleate; Drug Synergism; Glutamic Acid; Histamine; Histamine H1 Antagonists; N-Methylaspartate; Neurons; Piperazines; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Terfenadine; Triprolidine | 2000 |
VUF-K-8788, a periphery-selective histamine H1 antagonist with anti-pruritic activities.
Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Benzimidazoles; Capillary Permeability; Guinea Pigs; Histamine; Histamine H1 Antagonists; In Vitro Techniques; Ketotifen; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Muscle Contraction; Passive Cutaneous Anaphylaxis; Peripheral Nervous System; Piperazines; Pruritus; Pyrilamine; Rats; Rats, Wistar; Terfenadine; Thiazines | 2001 |
Involvement of thromboxane A2 and peptide leukotrienes in early and late phase nasal blockage in a guinea pig model of allergic rhinitis.
Topics: Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Benzoquinones; Chromones; Dexamethasone; Guinea Pigs; Heptanoic Acids; Histamine; Histamine Release; Leukotrienes; Male; Nasal Cavity; Nasal Obstruction; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine; Therapeutic Irrigation; Thromboxane A2 | 2001 |
Inhibitory effects of oral prednisolone and fexofenadine on skin responses by prick tests with histamine and compound 48/80.
Topics: Administration, Oral; Adult; Anti-Allergic Agents; Female; Glucocorticoids; Histamine; Humans; Hypersensitivity, Immediate; Male; p-Methoxy-N-methylphenethylamine; Prednisolone; Skin Tests; Terfenadine | 2002 |
[Effect of fexofenadine--selective antagonist of histamine receptor (H1) on histamine-induced bronchoconstriction].
Topics: Adult; Anti-Allergic Agents; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Dose-Response Relationship, Drug; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Receptors, Histamine H1; Terfenadine; Time Factors | 2003 |
RNA synthesis-dependent potentiation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor-mediated toxicity by antihistamine terfenadine in cultured rat cerebellar neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Aniline Compounds; Animals; Animals, Newborn; Calcium; Cell Survival; Cells, Cultured; Cerebellum; Dactinomycin; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Histamine; Histamine H1 Antagonists; Kainic Acid; Neurons; Protein Synthesis Inhibitors; Rats; Receptors, AMPA; RNA; Terfenadine; Xanthenes | 2003 |
H1-receptor blocker antihistamine, terfenadine durably influences the glucocorticoid receptor, and lymphocyte histamine content of weanling rats.
Topics: Animals; Ascitic Fluid; Cytosol; Female; Flow Cytometry; Histamine; Histamine H1 Antagonists; Liver; Lymphocyte Count; Lymphocytes; Mast Cells; Rats; Receptors, Glucocorticoid; Receptors, Histamine H1; Terfenadine; Thymus Gland | 2003 |
Terfenadine antagonism against interleukin-4-modulated gene expression of T cell cytokines.
Topics: Anti-Allergic Agents; Drug Interactions; Gene Expression; Histamine; Humans; In Vitro Techniques; Interleukin-10; Interleukin-4; Interleukin-5; RNA, Messenger; Terfenadine; Th2 Cells; Transcription Factor AP-1 | 2003 |
Inhibition of tryptase release from human colon mast cells by histamine receptor antagonists.
Topics: Calcimycin; Cells, Cultured; Cimetidine; Colon; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Imidazoles; Ionophores; Mast Cells; Serine Endopeptidases; Serine Proteinase Inhibitors; Terfenadine; Thiourea; Tryptases | 2005 |
Potent pruritogenic action of tryptase mediated by PAR-2 receptor and its involvement in anti-pruritic effect of nafamostat mesilate in mice.
Topics: Animals; Antibodies; Antipruritics; Benzamidines; Dose-Response Relationship, Drug; Extravasation of Diagnostic and Therapeutic Materials; Guanidines; Histamine; Histamine H1 Antagonists; Injections, Intradermal; Leupeptins; Male; Mast Cells; Mice; Mice, Inbred ICR; Mice, Mutant Strains; Oligopeptides; p-Methoxy-N-methylphenethylamine; Pruritus; Receptor, PAR-2; Serine Endopeptidases; Serotonin; Skin; Terfenadine; Time Factors; Tryptases | 2006 |
Application of a mathematical topological pattern of antihistaminic activity for the selection of new drug candidates and pharmacology assays.
Topics: Aniline Compounds; Animals; Anthracenes; Benzothiazoles; Databases, Factual; Dermatitis; Drug Design; Female; Histamine; Histamine H1 Antagonists; Hypnotics and Sedatives; Linear Models; Mathematics; Phenols; Rats; Rats, Wistar; Structure-Activity Relationship; Terfenadine | 2006 |
In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist.
Topics: Animals; Benzimidazoles; Bradykinin; Bronchial Spasm; Capillary Permeability; Cetirizine; Dermatitis; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; Hypersensitivity; Male; Mice; Molecular Structure; Oxazolone; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H1; Serotonin; Structure-Activity Relationship; Terfenadine; Time Factors | 2006 |
Involvement of ionotropic purinergic receptors in the histamine-induced enhancement of the cough reflex sensitivity in guinea pigs.
Topics: Adenosine Triphosphate; Administration, Inhalation; Animals; Citric Acid; Cough; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Histamine; Histamine H1 Antagonists, Non-Sedating; Male; Purinergic P2 Receptor Antagonists; Receptors, Histamine H1; Receptors, Purinergic P2; Receptors, Purinergic P2X; Reflex; Terfenadine | 2006 |
Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellular carcinoma cells.
Topics: Animals; Apoptosis; beta Catenin; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Enzyme Activation; Exocytosis; Female; Histamine; Histamine Antagonists; Humans; Inhibitor of Apoptosis Proteins; Liver Neoplasms; Mast Cells; Microtubule-Associated Proteins; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Ranitidine; Rats; Rats, Wistar; Receptors, Histamine; Survivin; Terfenadine | 2007 |
Atopic cough-like cough hypersensitivity caused by active sensitization with protein fraction of Aspergillus restrictus strain A-17.
Topics: Administration, Inhalation; Animals; Antigens, Fungal; Antitussive Agents; Aspergillus; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Citric Acid; Cough; Dose-Response Relationship, Drug; Fungal Proteins; Guinea Pigs; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Male; Methacholine Chloride; Respiratory Hypersensitivity; Terfenadine | 2008 |
Activation of proteinase-activated receptors induces itch-associated response through histamine-dependent and -independent pathways in mice.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists, Non-Sedating; Injections, Intradermal; Male; Mice; Mice, Inbred ICR; Oligopeptides; Pruritus; Receptor, PAR-1; Receptor, PAR-2; Receptors, Proteinase-Activated; Receptors, Thrombin; Terfenadine; Time Factors | 2008 |
Multiple H1-antihistamine-induced urticaria.
Topics: Administration, Oral; Adult; Drug Eruptions; Female; Histamine; Histamine H1 Antagonists; Humans; Immunologic Tests; Leukotriene B4; Loratadine; Piperidines; Pyridines; Skin Tests; Terfenadine; Urticaria | 2009 |
Leukotriene B(4) mediates sphingosylphosphorylcholine-induced itch-associated responses in mouse skin.
Topics: Animals; Calcium; Dermatitis, Atopic; Ganglia, Spinal; Histamine; Histamine H1 Antagonists, Non-Sedating; Injections, Intradermal; Keratinocytes; Leukotriene B4; Male; Mast Cells; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Neurons; Phosphorylcholine; Pruritus; Skin; Sphingomyelins; Sphingosine; Terfenadine | 2009 |
Histamine influence on apoptosis in trophoblast cell cultures.
Topics: Adult; Anti-Inflammatory Agents; Apoptosis; Cell Differentiation; Cells, Cultured; Dexamethasone; Enzyme-Linked Immunosorbent Assay; Female; Histamine; Histamine H1 Antagonists; Humans; Placenta; Pregnancy; Terfenadine; Trophoblasts; Young Adult | 2010 |
Effects of fexofenadine on inflammatory mediators in nasal lavage fluid in intermittent allergic rhinitis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antigens, Plant; Artemisia; Betula; Disease Progression; Eosinophil Cationic Protein; Female; Histamine; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Leukotriene D4; Male; Middle Aged; Nasal Lavage Fluid; Pollen; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2009 |
Inhibitory effects of the methanol extract of Ganoderma lucidum on mosquito allergy-induced itch-associated responses in mice.
Topics: Animals; Antipruritics; Culicidae; Drugs, Chinese Herbal; Fruit; Histamine; Histamine H1 Antagonists, Non-Sedating; Histamine Release; Hypersensitivity; Injections, Intradermal; Male; Mast Cells; Methanol; Mice; Mice, Inbred ICR; Phthalazines; Phytotherapy; Pruritus; Receptors, Histamine; Reishi; Skin; Terfenadine | 2010 |
Effect of histamine H1 receptor antagonists on TARC/CCL17 and MDC/CCL22 production from CD14+ cells induced by antigenic stimulation in vitro.
Topics: Adult; Antigens, Plant; Cell Proliferation; Chemokine CCL17; Chemokine CCL22; Chlorpheniramine; Extracellular Signal-Regulated MAP Kinases; GATA1 Transcription Factor; Gene Expression; Histamine; Histamine H1 Antagonists; Humans; Ketotifen; Leukocytes, Mononuclear; Lipopolysaccharide Receptors; Macrophages; Male; Middle Aged; NF-kappa B; Phosphorylation; Phthalazines; Piperazines; Plant Proteins; Rhinitis, Allergic, Seasonal; Signal Transduction; Terfenadine; Tuberculin; Young Adult | 2011 |
Histaminergic modulation of acetylcholine-induced γ oscillations in rat hippocampus.
Topics: Acetylcholine; Animals; Attention; Cholinesterase Inhibitors; Cimetidine; Dimaprit; Electroencephalography; Hippocampus; Histamine; Histamine Agonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Hypoxia, Brain; In Vitro Techniques; Male; Microelectrodes; Physostigmine; Pyramidal Tracts; Rats; Rats, Wistar; Terfenadine | 2011 |
Effects of bepotastine and fexofenadine on histamine-induced flare, wheal and itch.
Topics: Adult; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Piperidines; Pruritus; Pyridines; Skin; Terfenadine; Urticaria | 2012 |
Involvement of leukotriene B4 in itching in a mouse model of ocular allergy.
Topics: Allergens; Ambrosia; Animals; Conjunctivitis, Allergic; Disease Models, Animal; Glucocorticoids; Histamine; Histamine H1 Antagonists, Non-Sedating; Hydroxyurea; Immunoglobulin E; Immunoglobulin G; Immunosuppressive Agents; Injections, Intraocular; Injections, Subcutaneous; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mast Cells; Mice; Mice, Inbred ICR; Phenylpropionates; Pollen; Terfenadine | 2012 |
Induction of mast-cell accumulation by promutoxin, an Arg-49 phospholipase A2.
Topics: Animals; Bothrops; Cell Adhesion Molecules; Cyproheptadine; Ginkgolides; Histamine; Histamine Release; Inflammation; Lactones; Male; Mast Cells; Mice; Mice, Inbred BALB C; Peritoneum; Phospholipases A2; Phospholipases A2, Secretory; Platelet Activating Factor; Reptilian Proteins; Snake Venoms; Terfenadine | 2013 |
Impact of fexofenadine, osthole and histamine on peripheral blood mononuclear cell proliferation and cytokine secretion.
Topics: Adult; Cell Proliferation; Cells, Cultured; Coumarins; Cytokines; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Humans; Interleukin-10; Interleukin-6; Leukocytes, Mononuclear; Male; Terfenadine; Time Factors; Tumor Necrosis Factor-alpha | 2015 |
Cytokine production by PBMC and serum from allergic and non-allergic subjects following in vitro histamine stimulation to test fexofenadine and osthole anti-allergic properties.
Topics: Adult; Anti-Allergic Agents; Coumarins; Cytokines; Histamine; Humans; Hypersensitivity; Immunoglobulin E; Leukocytes, Mononuclear; Male; Terfenadine | 2016 |
Changes in gene expression induced by histamine, fexofenadine and osthole: Expression of histamine H
Topics: Adult; Case-Control Studies; Chemokine CCL5; Coumarins; Cyclooxygenase 2; Female; Gene Expression Regulation; Histamine; Humans; Hypersensitivity; Interleukin-1beta; Leukocytes, Mononuclear; Male; NF-kappa B; Receptors, Histamine H1; RNA, Messenger; Terfenadine | 2017 |
Asp73-dependent and -independent regulation of the affinity of ligands for human histamine H
Topics: Animals; Aspartic Acid; Cations, Monovalent; Chlorpheniramine; CHO Cells; Cricetulus; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Ligands; Mutation; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, Histamine H1; Sodium Chloride; Terfenadine | 2017 |
Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors.
Topics: Animals; Cyproheptadine; Histamine; Histamine Agonists; Histamine Antagonists; Mucous Membrane; Muscle, Smooth; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H2; Swine; Terfenadine; Urinary Bladder; Urothelium | 2019 |
A novel concept of immunological and allergy interactions in autism spectrum disorders: Molecular, anti-inflammatory effect of osthole.
Topics: Anti-Inflammatory Agents; Autism Spectrum Disorder; Child; Child, Preschool; Coumarins; Cyclooxygenase 2; Female; Histamine; Histamine Antagonists; Humans; Hypersensitivity; Infant; Leukocytes, Mononuclear; Male; Terfenadine | 2019 |