Page last updated: 2024-08-16

terfenadine and flurbiprofen

terfenadine has been researched along with flurbiprofen in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19904 (18.18)18.7374
1990's4 (18.18)18.2507
2000's3 (13.64)29.6817
2010's11 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caron, G; Ermondi, G1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Finnerty, JP; Harvey, A; Holgate, ST1
Hamid, M; Holgate, ST; Rafferty, P1
Finnerty, JP; Holgate, ST1
Holgate, ST; Lai, CK; Phillips, GD; Polosa, R1
Holgate, ST; Phillips, GD1
Finnerty, JP; Holgate, ST; Wilmot, C1
Curzen, N; Holgate, ST; Rafferty, P1
Brooks, CD; Karl, KJ1
Brouwer, KL; Dooley, MA; Falk, RJ; Frye, RF; Joy, MS; La, MK; Nolin, TD; Roberts, BV; Wang, J1
Bosilkovska, M; Daali, Y; Déglon, J; Desmeules, J; Samer, C; Staub, C; Walder, B1
Bosilkovska, M; Daali, Y; Dayer, P; Déglon, J; Desmeules, JA; Rebsamen, M; Samer, CF; Staub, C; Walder, B1
Bosilkovska, M; Daali, Y; Déglon, J; Desmeules, J; Samer, C; Thomas, A; Walder, B1

Trials

10 trial(s) available for terfenadine and flurbiprofen

ArticleYear
The relative contributions of histamine and prostanoids to bronchoconstriction provoked by isocapnic hyperventilation in asthma.
    The European respiratory journal, 1992, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Female; Flurbiprofen; Forced Expiratory Volume; Histamine; Humans; Hyperventilation; Male; Middle Aged; Placebos; Terfenadine

1992
The inhibitory effect of terfenadine and flurbiprofen on early and late-phase bronchoconstriction following allergen challenge in atopic asthma.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1990, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Allergens; Asthma; Benzhydryl Compounds; Bronchial Provocation Tests; Female; Flurbiprofen; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Male; Terfenadine

1990
Evidence for the roles of histamine and prostaglandins as mediators in exercise-induced asthma: the inhibitory effect of terfenadine and flurbiprofen alone and in combination.
    The European respiratory journal, 1990, Volume: 3, Issue:5

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Benzhydryl Compounds; Double-Blind Method; Exercise Test; Female; Flurbiprofen; Forced Expiratory Volume; Histamine H1 Antagonists; Histamine Release; Humans; Male; Prostaglandins; Randomized Controlled Trials as Topic; Terfenadine

1990
Contribution of histamine and prostanoids to bronchoconstriction provoked by inhaled bradykinin in atopic asthma.
    Allergy, 1990, Volume: 45, Issue:3

    Topics: Adult; Asthma; Benzhydryl Compounds; Bradykinin; Bronchial Provocation Tests; Female; Flurbiprofen; Histamine; Histamine H1 Antagonists; Humans; Male; Placebos; Terfenadine

1990
The effect of oral terfenadine alone and in combination with flurbiprofen on the bronchoconstrictor response to inhaled adenosine 5'-monophosphate in nonatopic asthma.
    The American review of respiratory disease, 1989, Volume: 139, Issue:2

    Topics: Adenosine Monophosphate; Administration, Inhalation; Administration, Oral; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Constriction, Pathologic; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Female; Flurbiprofen; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Propionates; Terfenadine

1989
Inhibition of hypertonic saline-induced bronchoconstriction by terfenadine and flurbiprofen. Evidence for the predominant role of histamine.
    The American review of respiratory disease, 1989, Volume: 140, Issue:3

    Topics: Adult; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Dose-Response Relationship, Drug; Double-Blind Method; Female; Flurbiprofen; Histamine; Histamine H1 Antagonists; Humans; Male; Propionates; Random Allocation; Saline Solution, Hypertonic; Sodium Chloride; Terfenadine

1989
Effects of a cyclo-oxygenase inhibitor, flurbiprofen, and an H1 histamine receptor antagonist, terfenadine, alone and in combination on allergen induced immediate bronchoconstriction in man.
    Thorax, 1987, Volume: 42, Issue:12

    Topics: Adult; Allergens; Asthma; Benzhydryl Compounds; Bronchi; Bronchial Provocation Tests; Drug Combinations; Flurbiprofen; Forced Expiratory Volume; Histamine; Histamine H1 Antagonists; Humans; Methacholine Compounds; Propionates; Terfenadine

1987
Hay fever treatment with combined antihistamine and cyclooxygenase-inhibiting drugs.
    The Journal of allergy and clinical immunology, 1988, Volume: 81, Issue:6

    Topics: Adult; Benzhydryl Compounds; Conjunctivitis; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Female; Flurbiprofen; Histamine H1 Antagonists; Humans; Male; Medical Records; Middle Aged; Pruritus; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine

1988
In vivo alterations in drug metabolism and transport pathways in patients with chronic kidney diseases.
    Pharmacotherapy, 2014, Volume: 34, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biological Transport; Breath Tests; Case-Control Studies; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Female; Flurbiprofen; Glomerulonephritis; Humans; Male; Middle Aged; Prospective Studies; Renal Insufficiency, Chronic; Terfenadine; Young Adult

2014
Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method.
    Basic & clinical pharmacology & toxicology, 2016, Volume: 119, Issue:3

    Topics: Adolescent; Adult; Bupropion; Caffeine; Cross-Over Studies; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Dose-Response Relationship, Drug; Dried Blood Spot Testing; Drug Interactions; Female; Flurbiprofen; Genotyping Techniques; Humans; Male; Midazolam; Omeprazole; Phenotype; Terfenadine; Young Adult

2016

Other Studies

12 other study(ies) available for terfenadine and flurbiprofen

ArticleYear
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma.
    Bioanalysis, 2014, Volume: 6, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bupropion; Caffeine; Calibration; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dextromethorphan; Dried Blood Spot Testing; Flurbiprofen; Half-Life; Male; Midazolam; Omeprazole; Pharmaceutical Preparations; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2014
Geneva cocktail for cytochrome p450 and P-glycoprotein activity assessment using dried blood spots.
    Clinical pharmacology and therapeutics, 2014, Volume: 96, Issue:3

    Topics: Administration, Oral; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bupropion; Caffeine; Capsules; Carbonated Beverages; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Coffee; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Dried Blood Spot Testing; Enzyme Inhibitors; Feasibility Studies; Flurbiprofen; Humans; Isoenzymes; Male; Midazolam; Omeprazole; Pharmaceutical Preparations; Phenotype; Pilot Projects; Predictive Value of Tests; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine; Young Adult

2014