terfenadine has been researched along with erythromycin in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (42.11) | 18.2507 |
| 2000's | 11 (28.95) | 29.6817 |
| 2010's | 10 (26.32) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Belas, F; Chaudhary, AK; Cvetkovic, M; Dempsey, PJ; Fromm, MF; Kim, RB; Leake, B; Roden, DM; Roden, MM; Wandel, C; Wilkinson, GR; Wood, AJ | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A | 1 |
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Adebesin, AM; Falck, JR; Fischer, R; Konkel, A; Lossie, J; Paudyal, MP; Puli, N; Schunck, WH; Vijaykumar, J; Wesser, T; Westphal, C; Zhu, C | 1 |
| Lockey, RF | 1 |
| Cantilena, LR; Conner, DP; Honig, PK; Woosley, RL; Zamani, K | 1 |
| Ciummo, PE; Katz, NL | 1 |
| Carlson, W; Choo, PW; Faich, GA; Greineder, D; Hanrahan, JP; Platt, R | 1 |
| Bruschetta, HR; Guzman, E; Niarchos, AP; Parente, TF; Paris, DG | 1 |
| Eiselt-Proteau, D; Haxby, D; Hedges, JR; Zechnich, AD | 1 |
| Gully, C; Riem, R | 1 |
| Biglin, KE; Constance, TD; Faraon, MS; Lieh-Lai, M | 1 |
| Sabbah, A | 1 |
| Oster, G; Thompson, D | 1 |
| Carlson, AM; Morris, LS | 1 |
| Cerimele, B; DeSante, K; Goldberg, MJ; Hatcher, B; Ring, B; Sides, G; Wrighton, S | 1 |
| Burkhart, GA; Honig, PK; Sevka, MJ; Temple, R | 1 |
| Delgado, LF; Naspitz, CK; Pferferman, A; Solé, D | 1 |
| Pasco, J | 1 |
| Shaikh, WA | 1 |
| Bastlund, J; Evans, AM; Jørgensen, KL; Larsen, LA; Milne, RW; Stretch, GR | 1 |
| Emoto, C; Iketaki, H; Nakajima, M; Satoh, T; Shimada, N; Shimizu, R; Suzuki, S; Yamasaki, S; Yamazaki, H; Yokoi, T | 1 |
| Bondesson, U; Borga, O; Hedeland, M; Lennernas, H; Nyberg, L; Petri, N | 1 |
| Kataoka, M; Masaoka, Y; Sakuma, S; Yamashita, S; Yokoyama, T | 1 |
| Crumb, WJ | 1 |
| Butler, AS; Dempsey, CE; El Harchi, A; Hancox, JC; Zhang, Y | 1 |
1 review(s) available for terfenadine and erythromycin
| Article | Year |
|---|---|
Torsades de pointes induced by erythromycin and terfenadine.
Topics: Drug Therapy, Combination; Electrocardiography; Erythromycin; Female; Humans; Lidocaine; Magnesium; Middle Aged; Terfenadine; Torsades de Pointes | 1994 |
4 trial(s) available for terfenadine and erythromycin
| Article | Year |
|---|---|
Effect of dirithromycin on human CYP3A in vitro and on pharmacokinetics and pharmacodynamics of terfenadine in vivo.
Topics: Adult; Anti-Anxiety Agents; Anti-Bacterial Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biotransformation; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Erythromycin; Half-Life; Histamine H1 Antagonists; Humans; Hydroxylation; Macrolides; Male; Microsomes, Liver; Midazolam; Middle Aged; Oxidoreductases, N-Demethylating; Spectrophotometry, Ultraviolet; Terfenadine | 1996 |
Evaluation of the potential cardiotoxicity of the antihistamines terfenadine, astemizole, loratadine, and cetirizine in atopic children.
Topics: Anti-Allergic Agents; Anti-Bacterial Agents; Astemizole; Cetirizine; Child; Child, Preschool; Drug Interactions; Electrocardiography; Erythromycin; Female; Heart; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Loratadine; Male; Terfenadine | 1998 |
The changing face of antihistamines and cardiac adverse drug reactions: a clinical perspective.
Topics: Cardiovascular Diseases; Drug Interactions; Electrocardiography; Erythromycin; Female; Histamine H1 Antagonists; Humans; Male; Rhinitis, Allergic, Seasonal; Terfenadine; Torsades de Pointes | 2000 |
Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers.
Topics: Administration, Oral; Adult; Anti-Allergic Agents; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Capsules; Colon; Drug Synergism; Erythromycin; Female; Humans; Ileum; Intestinal Absorption; Intestinal Mucosa; Intubation; Jejunum; Male; Polyethylene; Reference Values; Terfenadine; Time Factors | 2006 |
33 other study(ies) available for terfenadine and erythromycin
| Article | Year |
|---|---|
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Male; Mice; Oxidoreductases, N-Demethylating; Pharmacokinetics; Substrate Specificity | 1999 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine | 2003 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of Robust 17(
Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Dose-Response Relationship, Drug; Drug Stability; Epoxide Hydrolases; Esterification; Hepatocytes; Humans; Male; Mice; Microsomes, Liver; Myocardial Infarction; Myocytes, Cardiac; Rats, Sprague-Dawley; Rats, Wistar | 2019 |
Medic alert!
Topics: Cardiovascular System; Drug Interactions; Erythromycin; Humans; Ketoconazole; Terfenadine | 1992 |
Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin.
Topics: Administration, Oral; Adult; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Erythromycin; Female; Heart; Humans; Male; Myocardium; Terfenadine | 1992 |
Interactions and drug-metabolizing enzymes.
Topics: Adolescent; Adult; Anti-Allergic Agents; Antidepressive Agents, Second-Generation; Antifungal Agents; Binding Sites; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Erythromycin; Female; Fluoxetine; Humans; Isoenzymes; Ketoconazole; Liver; Male; Middle Aged; Pharmaceutical Preparations; Terfenadine; Theophylline; Torsades de Pointes | 1995 |
Terfenadine-associated ventricular arrhythmias and QTc interval prolongation. A retrospective cohort comparison with other antihistamines among members of a health maintenance organization.
Topics: Administration, Oral; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Boston; Cohort Studies; Death, Sudden, Cardiac; Drug Interactions; Electrocardiography; Erythromycin; Female; Health Maintenance Organizations; Heart Rate; Histamine H1 Antagonists; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; Syncope; Terfenadine; Treatment Outcome; Ventricular Dysfunction | 1995 |
Possible interactions with terfenadine or astemizole.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Astemizole; Child; Drug Interactions; Drug Prescriptions; Erythromycin; Female; Humans; Ketoconazole; Male; Middle Aged; Retrospective Studies; Terfenadine | 1994 |
[Torsades de pointes caused by the association of terfenadine and erythromycin].
Topics: Drug Therapy, Combination; Erythromycin; Humans; Male; Middle Aged; Terfenadine; Torsades de Pointes | 1994 |
Drug-induced torsades de pointes: a possible interaction of terfenadine and erythromycin.
Topics: Adolescent; Cardiac Output; Drug Interactions; Erythromycin; Female; Humans; Respiration, Artificial; Terfenadine; Torsades de Pointes | 1994 |
[Teldane update. Interview with Dr. Alfred Sabbah, chief of the immuno-allergology laboratory of the C.H.U. d'Angers. Interview by Dr. Pierre Ceddaha].
Topics: Adult; Arrhythmias, Cardiac; Child; Child, Preschool; Contraindications; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Erythromycin; Humans; Hypersensitivity; Inactivation, Metabolic; Incidence; Infant; Josamycin; Ketoconazole; Microsomes, Liver; Retrospective Studies; Risk; Terfenadine | 1993 |
Use of terfenadine and contraindicated drugs.
Topics: Anti-Bacterial Agents; Antifungal Agents; Clarithromycin; Contraindications; Drug Interactions; Drug Utilization; Erythromycin; Histamine H1 Antagonists; Humans; Itraconazole; Ketoconazole; Pharmaceutical Services; Product Labeling; Retrospective Studies; Terfenadine; Troleandomycin | 1996 |
Coprescription of terfenadine and erythromycin or ketaconazole: an assessment of potential harm.
Topics: Anti-Allergic Agents; Anti-Bacterial Agents; Antifungal Agents; Clinical Pharmacy Information Systems; Drug Interactions; Erythromycin; Health Maintenance Organizations; Insurance Claim Review; Ketoconazole; Retrospective Studies; Terfenadine | 1996 |
Temporal decline in filling prescriptions for terfenadine closely in time with those for either ketoconazole or erythromycin.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Anti-Bacterial Agents; Antifungal Agents; Child; Child, Preschool; Drug Prescriptions; Erythromycin; Female; Health Maintenance Organizations; Humans; Infant; Ketoconazole; Male; Medicaid; Michigan; Middle Aged; Ohio; Terfenadine; United States | 1997 |
What has the patient been taking?
Topics: Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Chlorothiazide; Cimetidine; Diagnosis, Differential; Diuretics; Electrocardiography; Electrolytes; Erythromycin; Female; Histamine H1 Antagonists; Humans; Long QT Syndrome; Sodium Chloride Symporter Inhibitors; Terfenadine; Torsades de Pointes | 1998 |
Hepatic disposition of fexofenadine: influence of the transport inhibitors erythromycin and dibromosulphothalein.
Topics: Animals; Area Under Curve; Bile; Biological Transport, Active; Erythromycin; Histamine H1 Antagonists; Liver; Male; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sulfobromophthalein; Terfenadine | 2000 |
Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human.
Topics: Animals; Benzoflavones; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythromycin; GABA Modulators; Gastrointestinal Agents; Histamine H1 Antagonists; Humans; Inhibitory Concentration 50; Intestines; Kinetics; Mice; Microsomes; Microsomes, Liver; Midazolam; Mixed Function Oxygenases; Nifedipine; Oxygen; Protein Binding; Steroid Hydroxylases; Terfenadine; Testosterone; Vasodilator Agents | 2001 |
Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation.
Topics: Algorithms; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Drug Interactions; Erythromycin; Gene Expression; Glycerol; Humans; Intestinal Absorption; Loperamide; Models, Biological; Pharmaceutical Preparations; Propanolamines; Puromycin; Quinidine; Saquinavir; Solubility; Surface-Active Agents; Terfenadine; Verapamil; Vinblastine | 2011 |
Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels.
Topics: Binding Sites; Carrier Proteins; Clotrimazole; Dose-Response Relationship, Drug; Drug Interactions; Erythromycin; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Potassium Channel Blockers; Terfenadine; Thioridazine; Transfection; Tripartite Motif Proteins | 2014 |
The macrolide drug erythromycin does not protect the hERG channel from inhibition by thioridazine and terfenadine.
Topics: Antipsychotic Agents; Binding Sites; ERG1 Potassium Channel; Erythromycin; HEK293 Cells; Histamine H1 Antagonists, Non-Sedating; Humans; Inhibitory Concentration 50; Macrolides; Patch-Clamp Techniques; Terfenadine; Thioridazine | 2020 |