Page last updated: 2024-08-16

terfenadine and epinastine

terfenadine has been researched along with epinastine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's7 (41.18)18.2507
2000's8 (47.06)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Keserü, GM1
Caron, G; Ermondi, G1
Nagashima, R; Nishikawa, T; Tobita, M1
Jia, L; Sun, H1
Adamus, WS; Kuthan, H; Schilling, JC1
Bechtel, WD; Fügner, A; Kuhn, FJ; Mierau, J1
Iga, T; Kotaki, H; Ohtani, H; Sawada, Y1
Funae, Y; Hiroi, T; Igarashi, T; Kishimoto, W; Sakai, K1
Chachin, M; Horio, Y; Katayama, Y; Kitagawa, H; Kurachi, Y; Ohmura, T; Uchida, S; Yamada, M1
Danielson, L; DeVos, C; Grant, JA; Rihoux, JP1
Chachin, M; Igarashi, T; Ikeda, H; Ikegami, K; Kitagawa, H; Nagakura, A; Ohmura, T; Tarui, S; Uchida, S1
Hanada, E; Hirota, M; Iga, T; Kotaki, H; Nakaya, H; Ohtani, H; Sato, H; Sawada, Y; Uemura, H1
Izu, K; Tokura, Y1
Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Rahman, A; Takechi, K1
Fukui, H; Izumi, N; Mizuguchi, H; Ogino, S; Umehara, H1
dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1

Trials

3 trial(s) available for terfenadine and epinastine

ArticleYear
Antihistaminic activity and side effect profile of epinastine and terfenadine in healthy volunteers.
    International journal of clinical pharmacology, therapy, and toxicology, 1990, Volume: 28, Issue:12

    Topics: Administration, Oral; Adult; Affect; Benzhydryl Compounds; Dibenzazepines; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists; Humans; Imidazoles; Male; Middle Aged; Psychometrics; Reaction Time; Terfenadine

1990
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
    Allergy, 1999, Volume: 54, Issue:7

    Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria

1999
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 102, Issue:6

    Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria

2009

Other Studies

14 other study(ies) available for terfenadine and epinastine

ArticleYear
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
In vitro and in vivo studies of the non-sedating antihistamine epinastine.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:10

    Topics: Animals; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cats; Dibenzazepines; Dogs; Female; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Ileum; Imidazoles; In Vitro Techniques; Ketotifen; Male; Promethazine; Rats; Rats, Inbred Strains; Receptors, Histamine H1; Sleep; Terfenadine; Wakefulness

1988
A comparative pharmacokinetic-pharmacodynamic study of the electrocardiographic effects of epinastine and terfenadine in rats.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:4

    Topics: Animals; Bradycardia; Chromatography, High Pressure Liquid; Dibenzazepines; Dose-Response Relationship, Drug; Electrocardiography; Half-Life; Heart; Heart Rate; Histamine H1 Antagonists; Imidazoles; Infusions, Intravenous; Male; Rats; Rats, Sprague-Dawley; Terfenadine

1997
Metabolism of epinastine, a histamine H1 receptor antagonist, in human liver microsomes in comparison with that of terfenadine.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 98, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dibenzazepines; Histamine H1 Antagonists; Humans; Imidazoles; In Vitro Techniques; Intestine, Small; Isoenzymes; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Recombinant Proteins; Terfenadine

1997
Epinastine, a nonsedating histamine H1 receptor antagonist, has a negligible effect on HERG channel.
    European journal of pharmacology, 1999, Jun-25, Volume: 374, Issue:3

    Topics: Animals; Astemizole; Cation Transport Proteins; Dibenzazepines; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Gene Expression; Histamine H1 Antagonists; Humans; Imidazoles; Membrane Potentials; Oocytes; Potassium Channels; Potassium Channels, Voltage-Gated; Terfenadine; Trans-Activators; Transcriptional Regulator ERG; Xenopus

1999
Effects of terfenadine, astemizole and epinastine on electrocardiogram in conscious cynomolgus monkeys.
    European journal of pharmacology, 1999, Aug-06, Volume: 378, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Astemizole; Dibenzazepines; Electrocardiography; Heart Block; Histamine H1 Antagonists; Imidazoles; Macaca fascicularis; Male; Terfenadine; Time Factors

1999
Inhibitory effects of the antihistamines epinastine, terfenadine, and ebastine on potassium currents in rat ventricular myocytes.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:9

    Topics: Animals; Butyrophenones; Dibenzazepines; Electrophysiology; Heart Ventricles; Histamine H1 Antagonists; Imidazoles; Male; Patch-Clamp Techniques; Piperidines; Potassium Channels; Rats; Rats, Sprague-Dawley; Terfenadine

1999
The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis.
    The Journal of dermatology, 2005, Volume: 32, Issue:10

    Topics: Adult; Anti-Allergic Agents; Cetirizine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; E-Selectin; Female; Histamine H1 Antagonists; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Male; Olopatadine Hydrochloride; Substance P; Terfenadine; Vascular Cell Adhesion Molecule-1

2005
Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3

    Topics: Administration, Oral; Animals; Animals, Suckling; Chlorpheniramine; Cyproheptadine; Dibenzazepines; Diphenhydramine; Dose-Response Relationship, Drug; Electroencephalography; Electroshock; Histamine H1 Antagonists; Imidazoles; Ketotifen; Male; Rats; Rats, Wistar; Seizures; Terfenadine; Time Factors

2007
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
    Methods and findings in experimental and clinical pharmacology, 2008, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniramine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Imidazoles; Japan; Male; Middle Aged; Olopatadine Hydrochloride; Pain Measurement; Piperidines; Population Surveillance; Psychomotor Performance; Pyridines; Quality of Life; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sleep Stages; Surveys and Questionnaires; Terfenadine; Urticaria

2008
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016