Page last updated: 2024-08-16

terfenadine and desloratadine

terfenadine has been researched along with desloratadine in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.86)18.2507
2000's23 (65.71)29.6817
2010's11 (31.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hitchcock, SA1
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Ducic, I; Ko, CM; Morad, M; Shuba, Y1
Abdelaziz, MM; Devalia, JL; Khair, OA1
Affrime, M; Banfield, C; Batra, V; Clement, R; Gupta, S; Kantesaria, B; Marino, M1
Wilson, AM1
Affrime, M; Banfield, C; Gupta, S; Lim, J; Marino, M1
Haggart, K; Lipworth, BJ; Sims, EJ; Wilson, AM1
Bates, CE; Currie, GP; Lee, DK; Lipworth, BJ1
Jackson, CM; Lee, DK; Lipworth, BJ1
Glass, DJ; Harper, AS1
Grzelewska-Rzymowska, I1
Appajosyula, S; Gelfand, EW; Meeves, S1
Glass, D; Harper, A1
Fujihara, S; Gardiner, M; Haggart, K; Lee, DK; Lipworth, BJ1
Benedetti, MS; Diquet, B; Molimard, M1
Conboy-Ellis, K1
Baltes, E; Benedetti, MS; Chatelain, P; Gillard, M1
Camelo-Nunes, IC1
Blaiss, MS; Lehman, JM1
Kruszewski, J; Kłos, K; Sułek, K1
Kruszewski, J; Kruszewski, R; Kłos, K; Sułek, K1
Devillier, P; Faisy, C; Roche, N1
Bachert, C1
dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A1
Bagad, AS; Bahekar, PC; Chidrewar, GU; Mandhane, SN; Mehetre, SV; Pawar, CA; Rajamannar, T; Rao, CT; Shah, JH1
Moeller, ML; Nahata, MC; Phan, H1
Crowe, A; Wright, C1
Church, MK; Maurer, M1
Anoopkumar-Dukie, S; Grant, GD; Kavanagh, JJ; Naicker, P1
Chen, M; Chen, W; Chen, X; Guo, A; He, Y; Li, J; Liu, Z; Su, J; Wen, S; Yan, S; Zhang, C; Zhang, J; Zhao, Y; Zhou, H; Zhu, W1
Enk, CD; Levi, A1
Enk, CD; Hodak, E; Lapidoth, M; Levi, A; Mazor, S; Snast, I; Uvaidov, V1

Reviews

11 review(s) available for terfenadine and desloratadine

ArticleYear
Structural modifications that alter the P-glycoprotein efflux properties of compounds.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Central Nervous System Agents; Central Nervous System Diseases; Drug Design; Humans; Models, Molecular; Permeability; Structure-Activity Relationship

2012
Are antihistamines useful in managing asthma?
    Current opinion in allergy and clinical immunology, 2002, Volume: 2, Issue:1

    Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchospirometry; Cetirizine; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Loratadine; Mannitol; Quinolines; Rhinitis; Sulfides; Terfenadine

2002
[Clinical aspects of anti-inflammatory action of antihistamines].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2003, Volume: 14, Issue:84

    Topics: Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Loratadine; Piperazines; Terfenadine

2003
Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research.
    Current medical research and opinion, 2004, Volume: 20, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Histamine H1 Antagonists; Loratadine; Piperidines; Terfenadine

2004
Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:4

    Topics: Absorption; Animals; Area Under Curve; Benzimidazoles; Biological Availability; Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Metabolic Clearance Rate; Piperazines; Terfenadine; Tissue Distribution

2004
Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines.
    Journal of the American Academy of Nurse Practitioners, 2005, Volume: 17, Issue:8

    Topics: Adolescent; Adult; Cetirizine; Child; Child, Preschool; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Nurse Practitioners; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome

2005
New antihistamines: a critical view.
    Jornal de pediatria, 2006, Volume: 82, Issue:5 Suppl

    Topics: Anti-Allergic Agents; Blood-Brain Barrier; Central Nervous System Diseases; Cetirizine; Child; Cyproheptadine; Heart Diseases; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Loratadine; Mast Cells; Piperazines; Receptors, Histamine H1; Terfenadine

2006
Selecting the optimal oral antihistamine for patients with allergic rhinitis.
    Drugs, 2006, Volume: 66, Issue:18

    Topics: Administration, Oral; Cardiovascular System; Central Nervous System; Cetirizine; Drug Interactions; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Long QT Syndrome; Loratadine; Piperazines; Practice Guidelines as Topic; Quality of Life; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome

2006
Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.
    Clinical pharmacokinetics, 2008, Volume: 47, Issue:4

    Topics: Cetirizine; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine; Urticaria

2008
A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis.
    Clinical therapeutics, 2009, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cetirizine; Child; Clinical Trials as Topic; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Nasal Obstruction; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome; Young Adult

2009
H(1)-antihistamines and urticaria: how can we predict the best drug for our patient?
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2012, Volume: 42, Issue:10

    Topics: Anti-Allergic Agents; Cetirizine; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Predictive Value of Tests; Skin Tests; Terfenadine; Urticaria

2012

Trials

10 trial(s) available for terfenadine and desloratadine

ArticleYear
Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study.
    Clinical therapeutics, 2001, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Electrocardiography; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Terfenadine

2001
Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine.
    Clinical pharmacokinetics, 2002, Volume: 41, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Beverages; Biological Availability; Citrus; Confidence Intervals; Cross-Over Studies; Electrocardiography; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Terfenadine

2002
Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:10

    Topics: Adult; Air Pollutants; Allergens; Cross-Over Studies; Double-Blind Method; Environmental Exposure; Female; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Loratadine; Lung; Male; Pollen; Rhinitis, Allergic, Seasonal; Terfenadine

2002
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
    The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:2

    Topics: Acetates; Adenosine Monophosphate; Adult; Aged; Asthma; Bronchial Provocation Tests; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Piperazines; Respiratory Hypersensitivity; Terfenadine

2003
Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:4

    Topics: Adenosine Monophosphate; Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nasal Provocation Tests; Piperazines; Rhinitis, Allergic, Perennial; Terfenadine; Treatment Outcome

2004
[Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2006, Volume: 21, Issue:125

    Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Placebos; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria

2006
[The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2006, Volume: 21, Issue:125

    Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Regional Blood Flow; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria

2006
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 102, Issue:6

    Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria

2009
The effects of antihistamines with varying anticholinergic properties on voluntary and involuntary movement.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2013, Volume: 124, Issue:9

    Topics: Adult; Cholinergic Antagonists; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Promethazine; Reaction Time; Sleep Stages; Terfenadine; Tremor; Young Adult

2013
Association of FCER1A genetic polymorphisms with risk for chronic spontaneous urticaria and efficacy of nonsedating H1-antihistamines in Chinese patients.
    Archives of dermatological research, 2015, Volume: 307, Issue:2

    Topics: Adult; Asian People; Benzimidazoles; China; Female; Genotyping Techniques; Histamine H1 Antagonists, Non-Sedating; Humans; Immunoglobulin E; Loratadine; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Receptors, IgE; Terfenadine; Urticaria; Young Adult

2015

Other Studies

14 other study(ies) available for terfenadine and desloratadine

ArticleYear
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Comparative effects of loratadine and terfenadine on cardiac K+ channels.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:1

    Topics: Animals; Cation Transport Proteins; Ether-A-Go-Go Potassium Channels; Gene Expression; Guinea Pigs; Heart Ventricles; Histamine H1 Antagonists; In Vitro Techniques; Loratadine; Male; Membrane Potentials; Myocardium; Oocytes; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Rats; Rats, Wistar; Recombinant Proteins; Terfenadine; Xenopus laevis

1997
The potential of active metabolites of antihistamines in the management of allergic disease.
    Allergy, 2000, Volume: 55, Issue:5

    Topics: Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Cetirizine; Chymases; Eosinophils; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity; Intercellular Adhesion Molecule-1; Interleukin-3; Interleukin-8; Loratadine; Mast Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Prostaglandin D2; Pyridines; Recombinant Fusion Proteins; Recombinant Proteins; Serine Endopeptidases; Terfenadine; Time Factors; Tryptases

2000
Decongestant effects of antihistamines: a class effect?
    The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:3

    Topics: Controlled Clinical Trials as Topic; Histamine H1 Antagonists; Humans; Loratadine; Nasal Decongestants; Rhinitis, Allergic, Seasonal; Terfenadine

2003
Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine.
    BMC family practice, 2003, Aug-13, Volume: 4

    Topics: Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Patient Satisfaction; Rhinitis, Allergic, Seasonal; Sleep Wake Disorders; Terfenadine; Treatment Outcome

2003
Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine.
    Managed care interface, 2004, Volume: 17, Issue:2

    Topics: Anti-Allergic Agents; Cetirizine; Choice Behavior; Data Collection; Humans; Loratadine; Managed Care Programs; Nonprescription Drugs; Patient Satisfaction; Terfenadine; United States

2004
Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2005, Volume: 54, Issue:9

    Topics: Animals; Cetirizine; CHO Cells; Cricetinae; Cricetulus; Histamine H1 Antagonists; Humans; Loratadine; Piperazines; Predictive Value of Tests; Receptors, Histamine H1; Recombination, Genetic; Terfenadine; Urticaria

2005
Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.
    International archives of allergy and immunology, 2010, Volume: 151, Issue:1

    Topics: Acetates; Alcohols; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Cetirizine; Drug Interactions; Female; Guinea Pigs; Histamine H1 Antagonists, Non-Sedating; Hydroxyzine; Hypersensitivity; Immunoglobulin G; Interleukin-4; Leukocytes; Loratadine; Male; Mice; Mice, Inbred BALB C; Nasal Lavage Fluid; Nasal Mucosa; Pentobarbital; Piperazines; Sneezing; Terfenadine

2010
Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.
    Drugs, 2009, Volume: 69, Issue:18

    Topics: Acetates; Administration, Oral; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Astemizole; Cetirizine; Child; Cyclopropanes; Drug Administration Schedule; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Ketotifen; Leukotriene Antagonists; Loratadine; Piperazines; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Safety; Sulfides; Tablets; Terfenadine; Treatment Outcome

2009
The impact of P-glycoprotein mediated efflux on absorption of 11 sedating and less-sedating antihistamines using Caco-2 monolayers.
    Xenobiotica; the fate of foreign compounds in biological systems, 2012, Volume: 42, Issue:6

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cetirizine; Chromatography, High Pressure Liquid; Drug Interactions; Histamine H1 Antagonists; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Loratadine; Mass Spectrometry; Permeability; Terfenadine

2012
Treatment of solar urticaria using antihistamine and leukotriene receptor antagonist combinations tailored to disease severity.
    Photodermatology, photoimmunology & photomedicine, 2015, Volume: 31, Issue:6

    Topics: Acetates; Adolescent; Adult; Cetirizine; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Photosensitivity Disorders; Quinolines; Remission Induction; Remission, Spontaneous; Severity of Illness Index; Sulfides; Sunlight; Terfenadine; Ultraviolet Rays; Urticaria; Young Adult

2015
Real-life experience in the treatment of solar urticaria: retrospective cohort study.
    Clinical and experimental dermatology, 2019, Volume: 44, Issue:5

    Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Cohort Studies; Cyclopropanes; Disease Management; Female; Histamine Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Omalizumab; Photosensitivity Disorders; Quinolines; Retrospective Studies; Sulfides; Terfenadine; Urticaria; Young Adult

2019