terfenadine has been researched along with cetirizine in 155 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (6.45) | 18.7374 |
| 1990's | 57 (36.77) | 18.2507 |
| 2000's | 65 (41.94) | 29.6817 |
| 2010's | 23 (14.84) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S | 1 |
| Keserü, GM | 1 |
| Du, LP; Li, MY; Tsai, KC; Xia, L; You, QD | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Eddy, P; Goldman, E; Huang, W; Jia, ZJ; Kadambi, V; Scarborough, RM; Sinha, U; Song, Y; Su, T; Tumas, D; Zhang, P; Zhu, BY | 1 |
| Jia, L; Sun, H | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Sen, S; Sinha, N | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ghys, L; Mühlethaler, K; Rihoux, JP; Wüthrich, B | 1 |
| Barkley, AS; Millard, LG; Shall, L; Thompson, DA | 1 |
| Townley, RG | 1 |
| Naclerio, RM | 3 |
| Hill, S; Lever, LR; Marks, R; Rosenberg, R; Thompson, D | 1 |
| Fletcher, MP; Ryhal, BT | 1 |
| Soter, NA | 1 |
| Gillardin, JM; Gommeren, W; Janssen, PA; Janssen, PF; Leysen, JE; Sanz, G; Schotte, A | 1 |
| Coyle, AJ; Lefort, J; Vargaftig, BB | 1 |
| Fidler, C; Renton, R; Rosenberg, R | 1 |
| Bilsland, D; Ferguson, J | 1 |
| Backhouse, CI; Fidler, C; Renton, R; Rosenberg, RM | 1 |
| Andersson, M; Klementsson, H; Pipkorn, U | 1 |
| McMillan, JL; Simons, FE; Simons, KJ | 1 |
| Woodward, JK | 1 |
| Rafferty, P | 1 |
| Bernheim, J; Dijkman, JH; Hekking, PR; Molkenboer, JF; Nierop, G; Van Ganse, EH; Vanderschueren, R | 1 |
| Ghys, L; Kietzmann, H; Macher, E; Rihoux, JP | 1 |
| Kaiser, HB | 1 |
| Berman, BA | 1 |
| Lichtenstein, LM; Massey, WA | 1 |
| Simons, FE | 1 |
| Arendt, C; Boniver, R | 1 |
| Freidhoff, L; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Proud, D; Togias, AG | 1 |
| Rihoux, JP; Van Neste, DJ | 1 |
| Baroody, F; Freidhoff, L; Kagey-Sobotka, A; Lichtenstein, LM; Naclerio, RM; Norman, PS; Proud, D | 1 |
| Dupont, P; Rihoux, JP | 1 |
| Chung, M; Simons, FE; Simons, KJ; Yeh, J | 1 |
| Snowman, AM; Snyder, SH | 1 |
| Bloom, M; Dupont, P; Pechadre, JC; Rihoux, JP; Trolese, JF; Vernay, D | 1 |
| Rihoux, JP; Van Neste, D | 1 |
| Baltes, E; De Vos, C; Gobert, J; Maleux, MR | 1 |
| Benyon, RC; Church, MK; Lowman, MA; Okayama, Y | 1 |
| Alauzen, M; Bousquet, J; Campbell, AM; Fabre, JM; Marty-Ané, C; Souques, F | 1 |
| O'Hanlon, JF; Ramaekers, JG | 1 |
| Leduc, D; Pretolani, M; Vargaftig, BB; Zuany-Amorim, C | 1 |
| Abe, T; Matsuda, K; Nagai, H; Omata, T; Segawa, Y; Yoshida, K | 1 |
| Androsov, VN; Belostotskaia, OI; Il'ina, NI | 1 |
| Dowd, PM; Goldsmith, P | 1 |
| Sharpe, GR; Shuster, S | 1 |
| Bloom, M; Danglas, P; Hantzperg, M; Lambert, D | 1 |
| Andri, G; Andri, L; Betteli, C; Givanni, S; Lombardi, C; Mezzelani, P; Senna, GE | 1 |
| Findley, S; Lieberman, P; Lockey, RF; Mitchell, DQ; Nicodemus, CF; Woehler, T | 1 |
| Dockhorn, R; Grossman, J; Lockey, RF; Lumry, W; Mitchell, DQ; Widlitz, MD; Woehler, T | 1 |
| Comer, C; Harvey, RP; Marsh, W; Sanders, B; Shapiro, H; Westley, R; Wiener, M | 1 |
| Cabanis, MJ; Caplain, H; Chaufour, S; Rosenzweig, P; Thebault, JJ; Ulliac, N | 1 |
| Woosley, RL | 1 |
| Gupta, SK | 1 |
| DeMora, F; Ferrer, L; García, G; Puigdemont, A | 1 |
| Clark, S | 1 |
| Edwards, IR; Lindquist, M | 1 |
| Briscoe, MP; Clark, RH; Day, JH; Ellis, AK; Gervais, P | 1 |
| Delgado, LF; Naspitz, CK; Pferferman, A; Solé, D | 1 |
| Estes, KS; González, MA | 1 |
| Annunziato, L; Castaldo, P; Genovese, A; Giorgio, G; January, CT; Marone, G; Pannaccione, A; Taglialatela, M; Zhou, Z | 1 |
| Carmeliet, E | 1 |
| Burtin, B; Donnelly, F; Rihoux, JP | 1 |
| Inagaki, N; Kawasaki, H; Musoh, K; Nagai, H; Nagao, M; Nakamura, N | 1 |
| de Abajo, FJ; Rodríguez, LA | 1 |
| Mattila, MJ; Paakkari, I | 1 |
| Danielson, L; DeVos, C; Grant, JA; Rihoux, JP | 1 |
| Bousquet, J; Howarth, PH; Reynolds, R; Roi, L; Stern, MA | 1 |
| Collart, P; Nicolas, JM; Roba, J; Whomsley, R | 1 |
| Koenig, CJ; Phillips, RL | 1 |
| Dunn, N; Mann, RD; Pearce, GL; Shakir, S | 1 |
| Abdelaziz, MM; Devalia, JL; Khair, OA | 1 |
| Inagaki, N; Maeda, Y; Musoh, K; Nagai, H; Tanaka, H | 1 |
| Benedetto, SR; Duncan, BS; Sloan, AS | 1 |
| Annunziato, L; Cataldi, M; Di Renzo, G; Giorgio, G; Secondo, A; Taglialatela, M; Valore, M | 1 |
| Duvernelle, C; Frossard, N; Melac, M; Pauli, G; Purohit, A | 1 |
| Burtin, B; De Vos, C; Donnelly, F; Horak, F; Kavina, A; Stübner, P; Zieglmayer, R | 1 |
| Cummins, G; Lee, J; Okamoto, L | 1 |
| Cummins, G; Leahy, M; Liao, E | 1 |
| Annunziato, L; Castaldo, P; Fresi, A; Giorgio, G; Pannaccione, A; Rosati, B; Secondo, A; Taglialatela, M; Wanke, E | 1 |
| DeVos, C; Grant, JA; Moulaert, B; Riethuisen, JM | 1 |
| Wilson, AM | 1 |
| Fridliand, DG; Gushchin, IS; Poroshina, IuA; Shul'zhenko, AE | 1 |
| Paakkari, I | 1 |
| Spencer, HM | 1 |
| Itoh, M; Iwabuchi, K; Mochizuki, H; Sakurada, Y; Tashiro, M; Watanabe, T; Yanai, K | 1 |
| Abraham, D; Saltoun, CA | 1 |
| Cheung, BS; Heskin, R; Hofer, KD | 1 |
| Bates, CE; Currie, GP; Lee, DK; Lipworth, BJ | 1 |
| Boyce, M; Carey, W; Luria, X; Warrington, S | 1 |
| Goritz, SS; J Semus, M; Simons, FE; Simons, KJ | 1 |
| Duchateau, J; Heenen, M; Sternon, J | 1 |
| Grzelewska-Rzymowska, I | 1 |
| Portnoy, JM; Simon, SD | 1 |
| Georges, G; Hampel, F; Liao, Y; Mansfield, L; Meeves, S; Ratner, P | 1 |
| Dogra, S; Handa, S; Kumar, B | 1 |
| Glass, D; Harper, A | 1 |
| Fujihara, S; Gardiner, M; Haggart, K; Lee, DK; Lipworth, BJ | 1 |
| Fooanant, S; Roongapinun, S; Wajajamreon, S | 1 |
| Aoki, M; Funaki, Y; Itoh, M; Iwabuchi, K; Iwata, R; Kato, M; Mochizuki, H; Sakurada, Y; Tashiro, M; Wong, DF; Yanai, K | 1 |
| Benedetti, MS; Diquet, B; Molimard, M | 1 |
| Iizuka, H; Ishida-Yamamoto, A; Takahashi, H | 1 |
| Deslandes, B; Frossard, N; N'Gom, AS; Pauli, G; Purohit, A | 1 |
| Fujieda, S; Hyo, S; Kawada, R; Kitazawa, S; Takenaka, H | 1 |
| Horak, F; Kavina, A; Lemell, P; Zieglmayer, PU; Zieglmayer, R | 1 |
| Conboy-Ellis, K | 1 |
| Dhar, S; Georges, G; Varghese, ST | 1 |
| Baltes, E; Benedetti, MS; Chatelain, P; Gillard, M | 1 |
| Izu, K; Tokura, Y | 1 |
| Berisa, A; Corcóstegui, R; Innerárity, A; Labeaga, L; Orjales, A | 1 |
| Brunton, S; Spangler, DL | 1 |
| Burtin, B; Hohlfeld, JM; Krug, N; Larbig, M; Luettig, B; Martin, L; Stamm, H | 1 |
| Camelo-Nunes, IC | 1 |
| Blaiss, MS; Lehman, JM | 1 |
| Codreanu, A; de Chillou, C; Moneret-Vautrin, DA | 1 |
| Aragane, Y; Ashenager, MS; Grgela, T; Kawada, A | 1 |
| Kruszewski, J; Kłos, K; Sułek, K | 1 |
| Kruszewski, J; Kruszewski, R; Kłos, K; Sułek, K | 1 |
| Karakuş, S; Küçükgüzel, I; Küçükgüzel, SG | 1 |
| Morita, E; Takahashi, H; Zhang, Y | 1 |
| Devillier, P; Faisy, C; Roche, N | 1 |
| Boev, R; De Vos, C; Derde, MP; Mitchev, K; Pinelli, ME | 1 |
| Fukui, H; Izumi, N; Mizuguchi, H; Ogino, S; Umehara, H | 1 |
| Crawley, G; Moore, J; Rice, GM; Vacchiano, C | 1 |
| Bachert, C | 1 |
| Bagad, AS; Bahekar, PC; Chidrewar, GU; Mandhane, SN; Mehetre, SV; Pawar, CA; Rajamannar, T; Rao, CT; Shah, JH | 1 |
| Horak, F; Lemell, P; Zieglmayer, P; Zieglmayer, R | 1 |
| Moeller, ML; Nahata, MC; Phan, H | 1 |
| Alnouti, Y; Flynn, CA; Reed, GA | 1 |
| Crowe, A; Wright, C | 1 |
| Church, MK; Maurer, M | 1 |
| Church, MK; Maurer, M; Schoepke, N | 1 |
| Plichta, D; Spiewak, R | 1 |
| Cherian, R; Csanaky, IL; Dileepan, KN; Flynn, CA; Kassel, KM; Klaassen, CD; Lickteig, AL; Luyendyk, JP; Pratt-Hyatt, MJ; Raveendran, VV; Reed, GA; Smith, DD; Williams, KJ | 1 |
| Dileepan, KN; Flynn, CA; Milne, G; Raveendran, VV; Reed, GA; Smith, DD; Sweeney, ME; Tan, X; Tawfik, OW | 1 |
| Grobosch, T; Hiraoka, K; Ishii, K; Ishiwata, K; Maurer, M; Oda, K; Tashiro, M; Toyohara, J; Yanai, K | 1 |
| Enk, CD; Levi, A | 1 |
| Borowska, E; Bourgin, M; Hollender, J; Kienle, C; McArdell, CS; von Gunten, U | 1 |
| Grobosch, T; Hiraoka, K; Inami, A; Komamura, H; Matsuda, R; Maurer, M; Miyake, M; Takeda, K; Tashiro, M; Yamada, Y; Yanai, K | 1 |
| Hasselstrøm, SB; Kristensen, DM; Munkboel, CH; Styrishave, B | 1 |
| Apfelbacher, CJ; Böhmer, MM; Carter, B; Jupiter, A; Matterne, U; Weisshaar, E | 1 |
| Matsune, S; Okubo, K; Otsuka, H; Otsuka, K | 1 |
| Enk, CD; Hodak, E; Lapidoth, M; Levi, A; Mazor, S; Snast, I; Uvaidov, V | 1 |
| Bernstein, DI; Hassoun, Y; Stevenson, MR | 1 |
| Chen, T; Fu, LX; Lu, YH; Wang, L; Zhou, PM | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
25 review(s) available for terfenadine and cetirizine
| Article | Year |
|---|---|
Antiallergic properties of the second-generation H1 antihistamines during the early and late reactions to antigen.
Topics: Antigens; Asthma; Cetirizine; Chemotaxis, Leukocyte; Cold Temperature; Forced Expiratory Volume; Histamine H1 Antagonists; Histamine Release; Humans; Nasal Provocation Tests; Neutrophils; Physical Exertion; Skin Tests; SRS-A; Terfenadine; Time Factors | 1992 |
The second-generation antihistamines. What makes them different?
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Blood-Brain Barrier; Brain; Cetirizine; Cyproheptadine; Education, Medical, Continuing; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Loratadine; Terfenadine | 1991 |
Antihistamines in the treatment of clinical asthma.
Topics: Animals; Asthma; Benzhydryl Compounds; Cetirizine; Dose-Response Relationship, Drug; Forced Expiratory Volume; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Delayed; Peak Expiratory Flow Rate; Phthalazines; Terfenadine | 1990 |
H1-receptor antagonist treatment of seasonal allergic rhinitis.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Ketotifen; Loratadine; Rhinitis, Allergic, Seasonal; Terfenadine | 1990 |
Perennial allergic rhinitis: clinical efficacy of a new antihistamine.
Topics: Benzhydryl Compounds; Cetirizine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hydroxyzine; Rhinitis, Allergic, Perennial; Terfenadine | 1990 |
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Prostaglandin D2; Rhinitis, Allergic, Seasonal; SRS-A; Terfenadine | 1990 |
Recent advances in H1-receptor antagonist treatment.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Receptors, Histamine H1; Rhinitis, Allergic, Perennial; Terfenadine; Urticaria | 1990 |
The new H1 antihistamines. Treatment of urticaria and other clinical problems.
Topics: Astemizole; Cetirizine; Dermatitis, Atopic; Histamine H1 Antagonists; Humans; Loratadine; Terfenadine; Triprolidine; Urticaria | 1993 |
Cardiac actions of antihistamines.
Topics: Animals; Astemizole; Cetirizine; Diphenhydramine; Drug Interactions; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Torsades de Pointes | 1996 |
Pharmacokinetic overview of oral second-generation H1 antihistamines.
Topics: Astemizole; Blood-Brain Barrier; Cetirizine; Histamine H1 Antagonists; Humans; Loratadine; Structure-Activity Relationship; Terfenadine; Therapeutic Equivalency; Torsades de Pointes | 1998 |
Variations among non-sedating antihistamines: are there real differences?
Topics: Astemizole; Benzimidazoles; Butyrophenones; Central Nervous System; Cetirizine; Drug Interactions; Heart; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Loratadine; Piperidines; Potassium Channel Blockers; Terfenadine; Triprolidine | 1999 |
Are antihistamines useful in managing asthma?
Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchospirometry; Cetirizine; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Loratadine; Mannitol; Quinolines; Rhinitis; Sulfides; Terfenadine | 2002 |
Cardiotoxicity of new antihistamines and cisapride.
Topics: Arrhythmias, Cardiac; Astemizole; Benzimidazoles; Butyrophenones; Cetirizine; Cisapride; Heart Diseases; Histamine H1 Antagonists; Humans; Loratadine; Piperidines; Serotonin Receptor Agonists; Terfenadine; Triprolidine | 2002 |
[H1 histamine antagonists].
Topics: Acetates; Anti-Allergic Agents; Cetirizine; Chemistry, Pharmaceutical; Histamine H1 Antagonists; Humans; Hypersensitivity; Piperazines; Rhinitis; Terfenadine; Urticaria | 2003 |
[Clinical aspects of anti-inflammatory action of antihistamines].
Topics: Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Loratadine; Piperazines; Terfenadine | 2003 |
Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.
Topics: Absorption; Animals; Area Under Curve; Benzimidazoles; Biological Availability; Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Metabolic Clearance Rate; Piperazines; Terfenadine; Tissue Distribution | 2004 |
Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines.
Topics: Adolescent; Adult; Cetirizine; Child; Child, Preschool; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Nurse Practitioners; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2005 |
Efficacy and central nervous system impairment of newer-generation prescription antihistamines in seasonal allergic rhinitis.
Topics: Central Nervous System; Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Quality of Life; Rhinitis, Allergic, Seasonal; Terfenadine | 2006 |
New antihistamines: a critical view.
Topics: Anti-Allergic Agents; Blood-Brain Barrier; Central Nervous System Diseases; Cetirizine; Child; Cyproheptadine; Heart Diseases; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Loratadine; Mast Cells; Piperazines; Receptors, Histamine H1; Terfenadine | 2006 |
Selecting the optimal oral antihistamine for patients with allergic rhinitis.
Topics: Administration, Oral; Cardiovascular System; Central Nervous System; Cetirizine; Drug Interactions; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Long QT Syndrome; Loratadine; Piperazines; Practice Guidelines as Topic; Quality of Life; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome | 2006 |
Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.
Topics: Cetirizine; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine; Urticaria | 2008 |
A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cetirizine; Child; Clinical Trials as Topic; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Nasal Obstruction; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome; Young Adult | 2009 |
H(1)-antihistamines and urticaria: how can we predict the best drug for our patient?
Topics: Anti-Allergic Agents; Cetirizine; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Predictive Value of Tests; Skin Tests; Terfenadine; Urticaria | 2012 |
[Pharmacotherapy of urticaria--an analysis of the discrepancies between guidelines of expert bodies, registration documents and evidence for the effectiveness of drugs].
Topics: Administration, Oral; Administration, Topical; Anti-Allergic Agents; Benzimidazoles; Cetirizine; Glucocorticoids; Histamine Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Piperidines; Poland; Practice Guidelines as Topic; Terfenadine; Treatment Outcome; Urticaria | 2013 |
Oral H1 antihistamines as 'add-on' therapy to topical treatment for eczema.
Topics: Administration, Oral; Administration, Topical; Adult; Cetirizine; Chemotherapy, Adjuvant; Child; Eczema; Histamine H1 Antagonists; Humans; Loratadine; Outcome Assessment, Health Care; Pruritus; Randomized Controlled Trials as Topic; Terfenadine | 2019 |
61 trial(s) available for terfenadine and cetirizine
| Article | Year |
|---|---|
The skin as a target organ for the investigation of antiallergic drugs: comparison between cetirizine and terfenadine.
Topics: Adolescent; Adult; Antigens; Cetirizine; Dermatitis; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Male; Middle Aged; Skin Tests; Terfenadine | 1992 |
Comparative inhibition profiles of three non-sedating antihistamines assessed by an extended Lewis model.
Topics: Adult; Analysis of Variance; Cetirizine; Cyproheptadine; Female; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Models, Biological; Single-Blind Method; Skin; Skin Tests; Terfenadine | 1992 |
Inhibition of mediator release during the early reaction to antigen.
Topics: Albumins; Antigens; Cetirizine; Esterases; Histamine; Humans; Kinins; Loratadine; Nasal Mucosa; Nasal Provocation Tests; Terfenadine; Tosylarginine Methyl Ester | 1992 |
Effects of cetirizine, loratadine and terfenadine on histamine weal and flare reactions.
Topics: Administration, Oral; Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Erythema; Female; Histamine; Histamine Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Random Allocation; Skin; Terfenadine | 1992 |
Multicenter, crossover study of the efficacy and tolerability of terfenadine, 120 mg, versus cetirizine, 10 mg, in perennial allergic rhinitis.
Topics: Adult; Cetirizine; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Rhinitis, Allergic, Seasonal; Terfenadine | 1991 |
A comparison of cetirizine and terfenadine in the management of solar urticaria.
Topics: Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Sunlight; Terfenadine; Urticaria | 1991 |
Multicentre, double-blind comparison of terfenadine and cetirizine in patients with seasonal allergic rhinitis.
Topics: Adult; Benzhydryl Compounds; Cetirizine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hydroxyzine; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal; Terfenadine | 1990 |
Allergen-induced increase in nonspecific nasal reactivity is blocked by antihistamines without a clear-cut relationship to eosinophil influx.
Topics: Allergens; Benzhydryl Compounds; Cetirizine; Double-Blind Method; Eosinophils; Histamine H1 Antagonists; Humans; Hydroxyzine; Immunity, Innate; Nasal Mucosa; Nasal Provocation Tests; Rhinitis, Allergic, Seasonal; Terfenadine | 1990 |
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria | 1990 |
Prophylactic treatment of grass pollen-induced asthma with cetirizine.
Topics: Adolescent; Adult; Aged; Asthma; Benzhydryl Compounds; Cetirizine; Child; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Medical Records; Middle Aged; Nasal Obstruction; Pollen; Rhinitis; Terfenadine | 1990 |
Comparison of cetirizine and terfenadine in the treatment of chronic idiopathic urticaria.
Topics: Benzhydryl Compounds; Cetirizine; Chronic Disease; Double-Blind Method; Histamine H1 Antagonists; Humans; Hydroxyzine; Terfenadine; Urticaria | 1990 |
The effects of antihistamines beyond H1 antagonism in allergic inflammation.
Topics: Benzhydryl Compounds; Cetirizine; Cyproheptadine; Dermatitis, Atopic; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hydroxyzine; Prostaglandin D2; Rhinitis, Allergic, Seasonal; SRS-A; Terfenadine | 1990 |
[Evaluation of cetirizine and of terfenadine in the treatment of perennial allergic rhinitis].
Topics: Adolescent; Adult; Benzhydryl Compounds; Cetirizine; Clinical Trials as Topic; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Terfenadine | 1989 |
In vivo and in vitro effects of antihistamines on mast cell mediator release: a potentially important property in the treatment of allergic disease.
Topics: Administration, Intranasal; Administration, Oral; Administration, Topical; Adolescent; Adult; Benzhydryl Compounds; Cetirizine; Histamine H1 Antagonists; Humans; Hydroxyzine; Mast Cells; Middle Aged; Respiratory Hypersensitivity; SRS-A; Terfenadine | 1989 |
Quantitative time course study of the skin response to histamine and the effect of H1 blockers. A 3-week crossover double-blind comparative trial of cetirizine and terfenadine.
Topics: Adult; Benzhydryl Compounds; Blood Flow Velocity; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Intradermal Tests; Lasers; Randomized Controlled Trials as Topic; Regional Blood Flow; Skin; Terfenadine | 1989 |
The effects of H1 antihistamines on the early allergic response.
Topics: Benzhydryl Compounds; Calcium Channels; Cetirizine; Dopamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Receptors, Adrenergic, alpha; Rhinitis; Serotonin; Terfenadine | 1989 |
Comparative study of the peripheral and central effects of terfenadine and cetirizine 2 HCl.
Topics: Adult; Benzhydryl Compounds; Central Nervous System; Cetirizine; Double-Blind Method; Drug Evaluation; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Middle Aged; Random Allocation; Skin Tests; Sleep Stages; Terfenadine | 1987 |
Comparison of the central and peripheral effects of cetirizine and terfenadine.
Topics: Adult; Benzhydryl Compounds; Cetirizine; Electroencephalography; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Male; Terfenadine; Time Factors; Urticaria | 1988 |
Inhibition of the cutaneous response to histamine by H1-blocking agents. Quantitative evaluation of microvascular changes in the skin after histamine challenge and a comparison of the effects of a single intake of cetirizine and terfenadine.
Topics: Adult; Benzhydryl Compounds; Cetirizine; Dermatitis; Double-Blind Method; Erythema; Female; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Injections, Intradermal; Lasers; Male; Microcirculation; Random Allocation; Regional Blood Flow; Rheology; Skin; Terfenadine | 1988 |
Antihistamine effects on actual driving performance in a standard test: a summary of Dutch experience, 1989-94.
Topics: Automobile Driving; Benzimidazoles; Butyrophenones; Cetirizine; Clemastine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Loratadine; Netherlands; Piperidines; Psychomotor Performance; Terfenadine; Triprolidine | 1995 |
Effects of antihistamines on inflammatory mediators.
Topics: Cetirizine; Chymases; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Humans; Loratadine; Nasal Provocation Tests; Prostaglandin D2; Serine Endopeptidases; Terfenadine; Tryptases | 1993 |
[The efficacy of the Zirtek (cetirizine) preparation in chronic recurrent urticaria and seasonal allergic rhinitis].
Topics: Adolescent; Adult; Cetirizine; Chronic Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Recurrence; Rhinitis, Allergic, Seasonal; Tablets; Terfenadine; Urticaria | 1994 |
The effect of antihistamines on the immediate allergic response: a comparative review.
Topics: Capillary Permeability; Cetirizine; Cyproheptadine; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Ketotifen; Mast Cells; Peptide Hydrolases; Phthalazines; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine | 1993 |
In dermographic urticaria H2 receptor antagonists have a small but therapeutically irrelevant additional effect compared with H1 antagonists alone.
Topics: Adolescent; Adult; Aged; Cetirizine; Double-Blind Method; Female; Humans; Male; Middle Aged; Ranitidine; Terfenadine; Urticaria | 1993 |
[Double-blind comparative study of terfenadine and cetirizine in chronic idiopathic urticaria].
Topics: Adolescent; Adult; Cetirizine; Child; Chronic Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Prospective Studies; Terfenadine; Treatment Outcome; Urticaria | 1993 |
A comparison of the efficacy of cetirizine and terfenadine. A double-blind, controlled study of chronic idiopathic urticaria.
Topics: Adult; Cetirizine; Chronic Disease; Double-Blind Method; Humans; Terfenadine; Urticaria | 1993 |
Effects of cetirizine versus terfenadine in seasonal allergic rhinitis.
Topics: Adult; Cetirizine; Female; Humans; Male; Middle Aged; Patient Satisfaction; Rhinitis, Allergic, Seasonal; Single-Blind Method; Terfenadine | 1993 |
Comparative study of cetirizine and terfenadine versus placebo in the symptomatic management of seasonal allergic rhinitis.
Topics: Adolescent; Adult; Aged; Cetirizine; Child; Double-Blind Method; Ephedrine; Female; Humans; Male; Middle Aged; Nasal Obstruction; Placebos; Pollen; Prospective Studies; Rhinitis, Allergic, Seasonal; Terfenadine | 1996 |
Model for outcomes assessment of antihistamine use for seasonal allergic rhinitis.
Topics: Adolescent; Adult; Cetirizine; Chlorpheniramine; Decision Making; Female; Formularies as Topic; Histamine H1 Antagonists; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Quality of Life; Rhinitis, Allergic, Seasonal; Terfenadine | 1996 |
Comparative wheal and flare study of mizolastine vs terfenadine, cetirizine, loratadine and placebo in healthy volunteers.
Topics: Adult; Benzimidazoles; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Loratadine; Male; Terfenadine | 1995 |
Reversion and antihistamines.
Topics: Anti-Asthmatic Agents; Asthma; Beclomethasone; Cetirizine; Cromolyn Sodium; Glucocorticoids; Histamine H1 Antagonists; Humans; Nasal Decongestants; Recurrence; Rhinitis, Allergic, Perennial; Terfenadine | 1996 |
Onset of action and efficacy of terfenadine, astemizole, cetirizine, and loratadine for the relief of symptoms of allergic rhinitis.
Topics: Adolescent; Adult; Anti-Allergic Agents; Astemizole; Cetirizine; Double-Blind Method; Environmental Exposure; Female; Humans; Loratadine; Male; Middle Aged; Pruritus; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine; Treatment Outcome | 1997 |
Evaluation of the potential cardiotoxicity of the antihistamines terfenadine, astemizole, loratadine, and cetirizine in atopic children.
Topics: Anti-Allergic Agents; Anti-Bacterial Agents; Astemizole; Cetirizine; Child; Child, Preschool; Drug Interactions; Electrocardiography; Erythromycin; Female; Heart; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Loratadine; Male; Terfenadine | 1998 |
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria | 1999 |
Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal allergic rhinitis.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Terfenadine; Time Factors | 1999 |
Twenty-four hours of activity of cetirizine and fexofenadine in the skin.
Topics: Adolescent; Adult; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Double-Blind Method; Drug Evaluation; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Rhinitis; Skin; Skin Tests; Terfenadine; Time Factors | 2001 |
Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis.
Topics: Adult; Anti-Allergic Agents; Bronchial Provocation Tests; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Humans; Kinetics; Male; Poaceae; Pollen; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine | 2001 |
A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.
Topics: Adult; Benzimidazoles; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Piperidines; Terfenadine; Treatment Outcome; Urticaria | 2002 |
Roles of histamine in regulation of arousal and cognition: functional neuroimaging of histamine H1 receptors in human brain.
Topics: Adult; Arousal; Brain; Brain Chemistry; Cetirizine; Cognition; Cross-Over Studies; Discrimination, Psychological; Double-Blind Method; Doxepin; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Psychomotor Performance; Radiopharmaceuticals; Reaction Time; Receptors, Histamine H1; Sleep Stages; Terfenadine; Tomography, Emission-Computed | 2002 |
Failure of cetirizine and fexofenadine to prevent motion sickness.
Topics: Adult; Analysis of Variance; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Motion Sickness; Nausea; Terfenadine; Treatment Failure | 2003 |
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
Topics: Acetates; Adenosine Monophosphate; Adult; Aged; Asthma; Bronchial Provocation Tests; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Piperazines; Respiratory Hypersensitivity; Terfenadine | 2003 |
Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.
Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Piperidines; Skin Tests; Terfenadine | 2002 |
H1-antihistaminic activity of cetirizine and fexofenadine in allergic children.
Topics: Anti-Allergic Agents; Cetirizine; Child; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Prospective Studies; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome | 2003 |
Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Double-Blind Method; Female; Humans; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sleep Stages; Terfenadine; Treatment Outcome | 2003 |
Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria.
Topics: Adolescent; Adult; Aged; Cetirizine; Double-Blind Method; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Terfenadine; Treatment Outcome; Urticaria | 2004 |
Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.
Topics: Adenosine Monophosphate; Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nasal Provocation Tests; Piperazines; Rhinitis, Allergic, Perennial; Terfenadine; Treatment Outcome | 2004 |
Comparative efficacy of wheal-and-flare suppression among various non-sedating antihistamines and the pharmacologic insights to their efficacy.
Topics: Adolescent; Adult; Cetirizine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Terfenadine; Urticaria | 2004 |
Central effects of fexofenadine and cetirizine: measurement of psychomotor performance, subjective sleepiness, and brain histamine H1-receptor occupancy using 11C-doxepin positron emission tomography.
Topics: Adult; Brain; Carbon Radioisotopes; Cetirizine; Cross-Over Studies; Double-Blind Method; Doxepin; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Positron-Emission Tomography; Practice Guidelines as Topic; Psychomotor Performance; Receptors, Histamine H1; Sleep Stages; Terfenadine | 2004 |
Effects of bepotastine, cetirizine, fexofenadine, and olopatadine on histamine-induced wheal-and flare-response, sedation, and psychomotor performance.
Topics: Adult; Cetirizine; Cross-Over Studies; Dermatitis, Atopic; Dibenzoxepins; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Iontophoresis; Male; Olopatadine Hydrochloride; Piperidines; Psychomotor Performance; Pyridines; Sleep Stages; Terfenadine | 2004 |
Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction.
Topics: Adolescent; Adult; Cetirizine; Cross-Over Studies; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Skin Tests; Terfenadine; Urticaria | 2004 |
The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen.
Topics: Adult; Cetirizine; Cryptomeria; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Japan; Loratadine; Male; Middle Aged; Pollen; Quality of Life; Rhinitis, Allergic, Seasonal; Sneezing; Surveys and Questionnaires; Terfenadine | 2005 |
Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administration.
Topics: Adult; Cetirizine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Nose Diseases; Patient Satisfaction; Piperazines; Terfenadine | 2005 |
Facial thermography is a sensitive tool to determine antihistaminic activity: comparison of levocetirizine and fexofenadine.
Topics: Adolescent; Adult; Cetirizine; Cross-Over Studies; Double-Blind Method; Face; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Nasal Provocation Tests; Nose; Piperazines; Skin Temperature; Terfenadine; Thermography | 2006 |
[Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].
Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Placebos; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2006 |
[The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].
Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Regional Blood Flow; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2006 |
Evaluation of the antihistamine effects of olopatadine, cetirizine and fexofenadine during a 24 h period: a double-blind, randomized, crossover, placebo-controlled comparison in skin responses induced by histamine iontophoresis.
Topics: Adult; Cetirizine; Cross-Over Studies; Dibenzoxepins; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Histamine Antagonists; Humans; Iontophoresis; Male; Olopatadine Hydrochloride; Skin; Terfenadine; Urticaria | 2008 |
Fexofenadine effects on cognitive performance in aviators at ground level and simulated altitude.
Topics: Adult; Aerospace Medicine; Altitude; Anti-Allergic Agents; Attention; Cetirizine; Cognition; Double-Blind Method; Female; Humans; Male; Placebos; Reaction Time; Sleep Stages; Terfenadine | 2008 |
The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge Chamber.
Topics: Adolescent; Adult; Allergens; Anti-Allergic Agents; Benzimidazoles; Cetirizine; Cross-Over Studies; Double-Blind Method; Eye Diseases; Histamine H1 Antagonists, Non-Sedating; Humans; Middle Aged; Nasal Mucosa; Nose Diseases; Ophthalmic Solutions; Piperidines; Placebos; Rhinitis, Allergic, Seasonal; Terfenadine | 2010 |
The inhibition by levocetirizine and fexofenadine of the histamine-induced wheal and flare response in healthy Caucasian and Japanese volunteers.
Topics: Adult; Asian People; Cetirizine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Germany; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Japan; Male; Pruritus; Skin; Terfenadine; Time Factors; Treatment Outcome; Urticaria; White People; Young Adult | 2013 |
Brain histamine H1 receptor occupancy measured by PET after oral administration of levocetirizine, a non-sedating antihistamine.
Topics: Administration, Oral; Brain; Carbon Radioisotopes; Cetirizine; Cross-Over Studies; Double-Blind Method; Doxepin; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Neuroimaging; Positron-Emission Tomography; Radioligand Assay; Receptors, Histamine H1; Sleep; Terfenadine; Young Adult | 2015 |
A simulated car-driving study on the effects of acute administration of levocetirizine, fexofenadine, and diphenhydramine in healthy Japanese volunteers.
Topics: Adult; Asian People; Automobile Driving; Cetirizine; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Psychomotor Performance; Reaction Time; Terfenadine; Young Adult | 2016 |
70 other study(ies) available for terfenadine and cetirizine
| Article | Year |
|---|---|
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water | 1998 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
The pharmacophore hypotheses of I(Kr) potassium channel blockers: novel class III antiarrhythmic agents.
Topics: Anti-Arrhythmia Agents; Models, Biological; Models, Molecular; Potassium Channel Blockers; Potassium Channels; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2004 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Inhibitory effect of carboxylic acid group on hERG binding.
Topics: Benzamidines; Carboxylic Acids; Ether-A-Go-Go Potassium Channels; Factor Xa Inhibitors; Humans | 2006 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Treatment of urticaria and angioedema: low-sedating H1-type antihistamines.
Topics: Angioedema; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Urticaria | 1991 |
[Non-sedative antihistaminics and binding to central and peripheral H1 histamine receptors].
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cerebellum; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Hydroxyzine; Kinetics; Loratadine; Lung; Organ Specificity; Protein Binding; Receptors, Histamine H1; Terfenadine | 1991 |
The effect of cetirizine on antigen-dependent leucopenia in the guinea-pig.
Topics: Animals; Benzeneacetamides; Benzhydryl Compounds; Blood Platelets; Cetirizine; Female; Guinea Pigs; Histamine H1 Antagonists; Hydroxamic Acids; Hydroxyzine; In Vitro Techniques; Leukocyte Count; Leukopenia; Leukotriene B4; Lipoxygenase Inhibitors; Male; Platelet Activating Factor; Pyrilamine; Terfenadine | 1991 |
Pharmacology of antihistamines.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Time Factors | 1990 |
The comparative pharmacokinetics of H1-receptor antagonists.
Topics: Adult; Age Factors; Astemizole; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; Cetirizine; Child; Chlorpheniramine; Dose-Response Relationship, Drug; Half-Life; Histamine H1 Antagonists; Humans; Hydroxyzine; Terfenadine | 1987 |
Receptor effects of cetirizine.
Topics: Animals; Benzhydryl Compounds; Blood-Brain Barrier; Brain Chemistry; Cetirizine; Guinea Pigs; Histamine H1 Antagonists; Hydroxyzine; Lung; Radioligand Assay; Rats; Receptors, Histamine H1; Terfenadine | 1987 |
Inhibition of histamine and allergen skin wheal by cetirizine in four animal species.
Topics: Allergens; Animals; Benzhydryl Compounds; Cetirizine; Clemastine; Dogs; Female; Guinea Pigs; Histamine; Histamine Antagonists; Hydroxyzine; Hypersensitivity, Immediate; Male; Mice; Mice, Inbred Strains; Pyrilamine; Rats; Rats, Inbred Strains; Skin; Species Specificity; Terfenadine | 1987 |
In vitro effects of H1-antihistamines on histamine and PGD2 release from mast cells of human lung, tonsil, and skin.
Topics: Cetirizine; Histamine H1 Antagonists; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Ketotifen; Lung; Mast Cells; Palatine Tonsil; Prostaglandin D2; Skin; Terfenadine | 1994 |
Pharmacologic heterogeneity of human lung and colon cells: effect of terfenadine and cetirizine.
Topics: Adult; Aged; Antibodies, Anti-Idiotypic; Cells, Cultured; Cetirizine; Colon; Cyclooxygenase Inhibitors; Eicosanoids; Histamine H1 Antagonists; Humans; Immunoglobulin E; Lipoxygenase Inhibitors; Lung; Middle Aged; Terfenadine | 1995 |
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release; Hydroxamic Acids; Indomethacin; Kinetics; Leukocyte Count; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred BALB C; Ovalbumin; Peritoneal Cavity; Peritonitis; Platelet Activating Factor; T-Lymphocytes; Tacrolimus; Terfenadine; Thiazoles; Zymosan | 1993 |
Effect of ZCR-2060, an antiallergic agent, on antigen-induced immediate- and late-phase increases in airway resistance in sensitized guinea pigs.
Topics: Airway Resistance; Anaphylaxis; Animals; Benzoates; Bronchi; Cetirizine; Female; Guinea Pigs; Ketotifen; Metyrapone; Ovalbumin; Piperidines; Prednisolone; Terfenadine | 1995 |
Effect of H1-antihistamines on histamine release from dispersed canine cutaneous mast cells.
Topics: Animals; Calcimycin; Cell Survival; Cetirizine; Concanavalin A; Dermatitis, Atopic; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Histamine Release; In Vitro Techniques; Ketotifen; Loratadine; Mast Cells; Skin; Substance P; Terfenadine | 1997 |
Dangers of non-sedating antihistamines.
Topics: Arrhythmias, Cardiac; Astemizole; Cetirizine; Heart Diseases; Histamine H1 Antagonists; Humans; Legislation, Drug; Liver Diseases; Loratadine; Terfenadine; United Kingdom | 1997 |
Risks of non-sedating antihistamines.
Topics: Adverse Drug Reaction Reporting Systems; Astemizole; Cetirizine; Histamine H1 Antagonists; Humans; Loratadine; Terfenadine; Triprolidine | 1997 |
Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines.
Topics: Animals; Astemizole; Cation Transport Proteins; Cetirizine; DNA-Binding Proteins; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Heart; Histamine H1 Antagonists; Humans; Loratadine; Oocytes; Potassium Channels; Potassium Channels, Voltage-Gated; Receptors, Histamine H1; Terfenadine; Trans-Activators; Transcriptional Regulator ERG; Transfection; Tumor Cells, Cultured; Xenopus laevis | 1998 |
Effects of cetirizine on the delayed K+ currents in cardiac cells: comparison with terfenadine.
Topics: Animals; Cetirizine; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Histamine H1 Antagonists; In Vitro Techniques; Ion Channel Gating; Myocardium; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Rabbits; Stereoisomerism; Terfenadine | 1998 |
The clinical efficacy of H1 antagonists in urticaria and rhinitis.
Topics: Anti-Allergic Agents; Cetirizine; Histamine H1 Antagonists; Humans; Loratadine; Mathematical Computing; Rhinitis, Allergic, Seasonal; Terfenadine; Urticaria | 1998 |
Participation of histamine H1 and H2 receptors in passive cutaneous anaphylaxis-induced scratching behavior in ICR mice.
Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Capillary Permeability; Cetirizine; Drug Interactions; Famotidine; Female; Free Radical Scavengers; Histamine; Histamine H2 Antagonists; Mice; Mice, Inbred ICR; p-Methoxy-N-methylphenethylamine; Passive Cutaneous Anaphylaxis; Ranitidine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Serotonin; Terfenadine; Time Factors | 1999 |
Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Astemizole; Case-Control Studies; Cetirizine; Child; Child, Preschool; Cohort Studies; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Female; Histamine H1 Antagonists; Humans; Infant; Infant, Newborn; Information Systems; Loratadine; Male; Middle Aged; Risk Factors; Tachycardia, Ventricular; Terfenadine; Triprolidine | 1999 |
Fexofenadine: new preparation. Terfenadine, without cardiotoxicity.
Topics: Cetirizine; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Histamine Antagonists; Humans; Rhinitis, Allergic, Seasonal; Risk Assessment; Terfenadine; Treatment Outcome; Urticaria | 1999 |
In vitro inhibition of human liver drug metabolizing enzymes by second generation antihistamines.
Topics: Astemizole; Benzimidazoles; Cetirizine; Cytochrome P-450 Enzyme Inhibitors; Dimethyl Sulfoxide; Enzyme Inhibitors; Glucuronosyltransferase; Histamine H1 Antagonists; Humans; Isoenzymes; Kinetics; Loratadine; Microsomes, Liver; Terfenadine | 1999 |
Antihistamines for atopic dermatitis.
Topics: Adolescent; Adult; Aged; Antipruritics; Cetirizine; Child; Clemastine; Dermatitis, Atopic; Double-Blind Method; Histamine H1 Antagonists; Humans; Middle Aged; Pruritus; Randomized Controlled Trials as Topic; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Reproducibility of Results; Terfenadine; Treatment Outcome | 2000 |
Sedation with "non-sedating" antihistamines: four prescription-event monitoring studies in general practice.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Cetirizine; Child; Child, Preschool; Consciousness Disorders; Female; Histamine H1 Antagonists; Humans; Infant; Infant, Newborn; Loratadine; Male; Middle Aged; Product Surveillance, Postmarketing; Sleep Stages; Terfenadine; Triprolidine | 2000 |
The potential of active metabolites of antihistamines in the management of allergic disease.
Topics: Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Cetirizine; Chymases; Eosinophils; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity; Intercellular Adhesion Molecule-1; Interleukin-3; Interleukin-8; Loratadine; Mast Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Prostaglandin D2; Pyridines; Recombinant Fusion Proteins; Recombinant Proteins; Serine Endopeptidases; Terfenadine; Time Factors; Tryptases | 2000 |
Effect of a novel anti-allergic agent, HSR-609, on antigen-induced airway hyperresponsiveness in mice.
Topics: Acetylcholine; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Benzoxepins; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Cetirizine; Disease Models, Animal; Eosinophilia; Histamine H1 Antagonists; Leukocytes; Male; Mice; Mice, Inbred BALB C; Peritoneal Cavity; Prednisolone; Pyridines; Terfenadine | 2000 |
Impact of interventions designed to increase market share and prescribing of fexofenadine at HMOs.
Topics: Analysis of Variance; Astemizole; Cetirizine; Cost Savings; Drug Costs; Drug Utilization; Health Maintenance Organizations; Histamine H1 Antagonists; Humans; Loratadine; Marketing of Health Services; Practice Patterns, Physicians'; Retrospective Studies; Terfenadine; United States | 2000 |
Pharmacological blockade of ERG K(+) channels and Ca(2+) influx through store-operated channels exerts opposite effects on intracellular Ca(2+) oscillations in pituitary GH(3) cells.
Topics: Animals; Anti-Arrhythmia Agents; Astemizole; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cation Transport Proteins; Cells, Cultured; Cetirizine; Electrophysiology; Ether-A-Go-Go Potassium Channels; Histamine H1 Antagonists; Hydroxyzine; Large-Conductance Calcium-Activated Potassium Channels; Nimodipine; Phenethylamines; Pituitary Gland; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Rats; Small-Conductance Calcium-Activated Potassium Channels; Sulfonamides; Terfenadine | 2000 |
Newer antihistamines.
Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Somnambulism; Terfenadine | 2001 |
A descriptive analysis of the use and cost of new-generation antihistamines in the treatment of allergic rhinitis: a retrospective database analysis.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Databases as Topic; Drug Utilization Review; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Retrospective Studies; Rhinitis, Allergic, Perennial; Terfenadine; United States | 2001 |
The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Cetirizine; Child; Cohort Studies; Drug Costs; Economics, Pharmaceutical; Female; Health Care Costs; Histamine H1 Antagonists; Humans; Loratadine; Male; Managed Care Programs; Middle Aged; Retrospective Studies; Rhinitis, Allergic, Perennial; Terfenadine; United States | 2001 |
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs).
Topics: Astemizole; Calcium; Calcium Channel Blockers; Calcium Channels; Cation Transport Proteins; Cetirizine; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Neuroblastoma; Norepinephrine; Potassium Channels; Potassium Channels, Voltage-Gated; Receptors, Histamine H1; Terfenadine; Trans-Activators; Transcriptional Regulator ERG; Tritium; Tumor Cells, Cultured | 2001 |
[Comparative antihistamine and anti-allergic effects of various antihistamine preparations].
Topics: Adult; Anti-Allergic Agents; Butyrophenones; Cetirizine; Clemastine; Female; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Male; Piperidines; Pollen; Terfenadine | 2002 |
The Rx-to-OTC switch of Claritin, Allegra, and Zyrtec: an unprecedented FDA response to petitioners and the protection of public health.
Topics: Anti-Allergic Agents; Cetirizine; Drug Approval; Drug Costs; Drug Labeling; Drug Prescriptions; Gatekeeping; Humans; Legislation, Drug; Loratadine; Nonprescription Drugs; Public Health Practice; Terfenadine; United States; United States Food and Drug Administration | 2002 |
Facial swelling and eosinophilia in a 44-year-old woman.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Angioedema; Cefuroxime; Cetirizine; Diagnosis, Differential; Drug Hypersensitivity; Edema; Eosinophilia; Face; Fatigue; Female; Humans; Hypereosinophilic Syndrome; Indoles; Lansoprazole; Methylprednisolone; Methylprednisolone Acetate; Omeprazole; Penicillins; Phenylcarbamates; Prednisone; Ranitidine; Recurrence; Sulfonamides; Syndrome; Terfenadine; Tosyl Compounds | 2002 |
Is 3-mm less drowsiness important?
Topics: Anti-Allergic Agents; Automobile Driving; Cetirizine; Humans; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sleep Stages; Terfenadine; Treatment Outcome | 2003 |
Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine.
Topics: Anti-Allergic Agents; Cetirizine; Choice Behavior; Data Collection; Humans; Loratadine; Managed Care Programs; Nonprescription Drugs; Patient Satisfaction; Terfenadine; United States | 2004 |
Assessing the therapeutic benefits of antihistamines for the treatment of chronic idiopathic urticaria--a requirement for well-designed comparative clinical studies.
Topics: Cetirizine; Histamine H1 Antagonists, Non-Sedating; Humans; Terfenadine; Treatment Outcome; Urticaria | 2005 |
Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines.
Topics: Animals; Cetirizine; CHO Cells; Cricetinae; Cricetulus; Histamine H1 Antagonists; Humans; Loratadine; Piperazines; Predictive Value of Tests; Receptors, Histamine H1; Recombination, Genetic; Terfenadine; Urticaria | 2005 |
The various effects of four H1-antagonists on serum substance P levels in patients with atopic dermatitis.
Topics: Adult; Anti-Allergic Agents; Cetirizine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; E-Selectin; Female; Histamine H1 Antagonists; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Male; Olopatadine Hydrochloride; Substance P; Terfenadine; Vascular Cell Adhesion Molecule-1 | 2005 |
In vivo pharmacological characterisation of bilastine, a potent and selective histamine H1 receptor antagonist.
Topics: Animals; Benzimidazoles; Bradykinin; Bronchial Spasm; Capillary Permeability; Cetirizine; Dermatitis; Dose-Response Relationship, Drug; Guinea Pigs; Histamine; Histamine Antagonists; Hypersensitivity; Male; Mice; Molecular Structure; Oxazolone; Piperidines; Rats; Rats, Wistar; Receptors, Histamine H1; Serotonin; Structure-Activity Relationship; Terfenadine; Time Factors | 2006 |
Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs.
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Asthmatic Agents; Butyrophenones; Cetirizine; Conjunctivitis, Allergic; Cromolyn Sodium; Diabetes Mellitus, Type 1; Heart; Histamine H1 Antagonists; Humans; Long QT Syndrome; Male; Piperazines; Piperidines; Rhinitis, Allergic, Seasonal; Terfenadine | 2006 |
Inhibition of cytokine-induced expression of T-cell cytokines by antihistamines.
Topics: Cells, Cultured; Cetirizine; Dibenzoxepins; Histamine H1 Antagonists, Non-Sedating; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-12; Interleukin-4; Interleukin-5; Loratadine; Olopatadine Hydrochloride; RNA, Messenger; T-Lymphocytes; Terfenadine | 2007 |
Development and validation of a rapid RP-HPLC method for the determination of cetirizine or fexofenadine with pseudoephedrine in binary pharmaceutical dosage forms.
Topics: Cetirizine; Chromatography, High Pressure Liquid; Dosage Forms; Histamine H1 Antagonists; Pharmaceutical Preparations; Pseudoephedrine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Terfenadine | 2008 |
Non-interventional study comparing treatment satisfaction in patients treated with antihistamines.
Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Aged, 80 and over; Cetirizine; Child; Child, Preschool; Data Collection; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Europe; Female; Histamine H1 Antagonists; Humans; Infant; Male; Middle Aged; Patient Satisfaction; Piperazines; Prevalence; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome; Urticaria | 2008 |
Analysis of disease-dependent sedative profiles of H(1)-antihistamines by large-scale surveillance using the visual analog scale.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asthma; Butyrophenones; Cetirizine; Child; Chlorpheniramine; Dermatitis, Atopic; Dibenzazepines; Dibenzoxepins; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Imidazoles; Japan; Male; Middle Aged; Olopatadine Hydrochloride; Pain Measurement; Piperidines; Population Surveillance; Psychomotor Performance; Pyridines; Quality of Life; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Sleep Stages; Surveys and Questionnaires; Terfenadine; Urticaria | 2008 |
Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.
Topics: Acetates; Alcohols; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Cetirizine; Drug Interactions; Female; Guinea Pigs; Histamine H1 Antagonists, Non-Sedating; Hydroxyzine; Hypersensitivity; Immunoglobulin G; Interleukin-4; Leukocytes; Loratadine; Male; Mice; Mice, Inbred BALB C; Nasal Lavage Fluid; Nasal Mucosa; Pentobarbital; Piperazines; Sneezing; Terfenadine | 2010 |
Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.
Topics: Acetates; Administration, Oral; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Astemizole; Cetirizine; Child; Cyclopropanes; Drug Administration Schedule; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Ketotifen; Leukotriene Antagonists; Loratadine; Piperazines; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Safety; Sulfides; Tablets; Terfenadine; Treatment Outcome | 2009 |
Quantification of the transporter substrate fexofenadine in cell lysates by liquid chromatography/tandem mass spectrometry.
Topics: Cell Extracts; Cetirizine; Chromatography, Liquid; HEK293 Cells; Humans; Least-Squares Analysis; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Terfenadine | 2011 |
The impact of P-glycoprotein mediated efflux on absorption of 11 sedating and less-sedating antihistamines using Caco-2 monolayers.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cetirizine; Chromatography, High Pressure Liquid; Drug Interactions; Histamine H1 Antagonists; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Loratadine; Mass Spectrometry; Permeability; Terfenadine | 2012 |
H1-antihistamines exacerbate high-fat diet-induced hepatic steatosis in wild-type but not in apolipoprotein E knockout mice.
Topics: Animals; Apolipoproteins E; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biomarkers; Cetirizine; Cholesterol Esters; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Histamine H1 Antagonists; Lipogenesis; Liver; Liver-Specific Organic Anion Transporter 1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organic Anion Transporters, Sodium-Independent; Severity of Illness Index; Terfenadine; Triglycerides | 2014 |
Chronic ingestion of H1-antihistamines increase progression of atherosclerosis in apolipoprotein E-/- mice.
Topics: Analysis of Variance; Animals; Apolipoproteins E; Atherosclerosis; Blood Chemical Analysis; CD36 Antigens; Cetirizine; Cholesterol, LDL; Diet, High-Fat; Disease Progression; Fluorescent Antibody Technique; Histamine H1 Antagonists; Male; Mast Cells; Mice; Mice, Knockout; Nitric Oxide Synthase; Signal Transduction; Terfenadine | 2014 |
Treatment of solar urticaria using antihistamine and leukotriene receptor antagonist combinations tailored to disease severity.
Topics: Acetates; Adolescent; Adult; Cetirizine; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Photosensitivity Disorders; Quinolines; Remission Induction; Remission, Spontaneous; Severity of Illness Index; Sulfides; Sunlight; Terfenadine; Ultraviolet Rays; Urticaria; Young Adult | 2015 |
Oxidation of cetirizine, fexofenadine and hydrochlorothiazide during ozonation: Kinetics and formation of transformation products.
Topics: Cetirizine; Chromatography, Liquid; Hydrochlorothiazide; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Ozone; Tandem Mass Spectrometry; Terfenadine; Wastewater; Water Pollutants, Chemical; Water Purification | 2016 |
Effects of antihistamines on the H295R steroidogenesis - Autocrine up-regulation following 3β-HSD inhibition.
Topics: 3-Hydroxysteroid Dehydrogenases; Autocrine Communication; Cell Line; Cell Survival; Cetirizine; Enzyme Inhibitors; Gene Expression Regulation; Histamine Antagonists; Histamine H1 Antagonists; Humans; Promethazine; Real-Time Polymerase Chain Reaction; Steroids; Terfenadine; Up-Regulation | 2018 |
Nasal Symptoms Reduction and Decreased Neutrophilia in Japanese Cedar Pollinosis With Prophylactic Treatment With a Combination of Montelukast, Fexofenadine, and Fluticasone Nasal Spray.
Topics: Acetates; Adult; Anti-Allergic Agents; Cetirizine; Cryptomeria; Cyclopropanes; Drug Therapy, Combination; Female; Fluticasone; Humans; Leukocyte Count; Leukotriene Antagonists; Male; Mast Cells; Middle Aged; Nasal Cavity; Nasal Sprays; Neutrophils; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Terfenadine; Treatment Outcome | 2019 |
Real-life experience in the treatment of solar urticaria: retrospective cohort study.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Cohort Studies; Cyclopropanes; Disease Management; Female; Histamine Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Omalizumab; Photosensitivity Disorders; Quinolines; Retrospective Studies; Sulfides; Terfenadine; Urticaria; Young Adult | 2019 |
Idiopathic postprandial diarrhea responsive to antihistamines.
Topics: Adult; Angioedema; Cetirizine; Diarrhea; Famotidine; Female; Food Hypersensitivity; Histamine Antagonists; Humans; Male; Middle Aged; Postprandial Period; Ranitidine; Terfenadine; Urticaria | 2019 |
Elevated YKL-40 serum levels in patients with chronic spontaneous urticaria.
Topics: Antigens, CD; Cadherins; Cell Line; Cetirizine; Chitinase-3-Like Protein 1; Chronic Urticaria; Histamine Antagonists; Humans; Mast Cells; Terfenadine | 2019 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |