Page last updated: 2024-08-16

terbutaline and metoprolol

terbutaline has been researched along with metoprolol in 80 studies

Research

Studies (80)

Timeframe	Studies, this research(%)	All Research%
pre-1990	40 (50.00)	18.7374
1990's	13 (16.25)	18.2507
2000's	16 (20.00)	29.6817
2010's	11 (13.75)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Gubernator, K; Kansy, M; Senner, F	1
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S	1
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Baker, JG	1
Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Conradi, R; Lee, PH; Shanmugasundaram, V	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Avdeef, A; Tam, KY	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Daniel, H; Flaten, GE; Isaksen, G; Karstad, R; Kottra, G; Stensen, W; Svendsen, JS; Svenson, J	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Carlsson, E; Fellenius, E; Gautier, E; Lundgren, B; Malatray, J	1
Larsson, S; Svedmyr, N	1
Björntorp, P; Fellenius, E; Smith, U; William-Olsson, T	1
Formgren, H	1
Ayajiki, K; Toda, N	1
Braat, MC; Jonkers, RE; van Boxtel, CJ	1
Chang, PI; Rutlen, DL	1
Bedi, GS	1
Jonkers, RE; Koopmans, RP; Portier, EJ; van Boxtel, CJ	1
Paull, JD; Ziccone, SP	1
Akhlaghi, S; Hughes, B; Kendall, M; Lewis, H	1
Jonkers, R; Koopmans, RP; Oosterhuis, B; van Boxtel, CJ	1
Gay, RG; Goldman, S; Lee, RW; Olajos, M; Raya, TE	1
Edoute, Y; Flavahan, NA; Ruff, F; Santais, MC; Vanhoutte, PM; Verbeuren, TJ; Zander, JF	1
Dahlöf, C; Löfdahl, CG; Olofsson, B; Svedmyr, N; Westergren, G	1
Gotzen, R; Meyer-Sabellek, W; Röcker, L; Schulte, KL; Thiede, HM	2
Katayama, H; Morishita, F; Yamada, K	1
Horst, MA; Robinson, CP	1
Lyrenäs, E	1
Bjellin, LA; Ek, BA; Lundgren, BT	1
Abrahamsson, H; Lyrenäs, E	1
Aoki, C; Iwabuchi, Y; Masuhara, T	1
Kondo, S; Morita, T; Tsuchida, S; Weiss, RM	1
Folgering, HT; Lammers, JW; van Herwaarden, CL	1
Potter, DE; Rowland, JM	1
Huckauf, H; Macha, HN; Wudicke, H; Wunderlich, J	1
Ahrén, B; Lundquist, I	1
Greefhorst, AP; van Herwaarden, CL	3
Elijah, D; Green, K; Lollis, G; Mayberry, L	1
Ek, B; Lundgren, B	1
Bax, ND; Lennard, MS; Tucker, GT	1
Carlsson, E; Hedberg, A; Mattsson, H	1
Löfdahl, CG; Marlin, GE; Svedmyr, N	2
Danielsson, A; Henriksson, R; Lindström, P; Sehlin, J	1
Brandi, ML; Rotella, CM; Toccafondi, RS; Zonefrati, R	1
Ekström, J; Malmberg, L	1
Carlsöö, B; Danielsson, A; Henriksson, R	1
Maggi, CA; Meli, A	1
Chowanetz, W; Schramm, A	1
Kitzmiller, JL; Nicolls, E; Ross, MG; Stubblefield, PG	1
Löfdahl, CG; Svedmyr, N	1
Grogaard, J; Sundell, H	1
van den Bergh, JH; van Herwaarden, CL	1
Arner, P; Enocksson, S; Lönnqvist, F; Nordenström, J; Shimizu, M	1
Kolesari, GL; Kuhlmann, RS; Lawrence, JM; Lenselink, DR	1
Iwabuchi, Y; Kimura, T	1
Cronhjort, M; Jacobsson, H; Jonsson, C	1
Boomershine, C; Chen, L; Lafuse, WP; Wang, T; Zwilling, BS	1
Amidon, GL; Hilgendorf, C; Langguth, P; Lipka, E; Regårdh, CG; Spahn-Langguth, H	1
Abrahamsson, B; Borgå, O; Månsson, W; Nyberg, L; Seidegård, J	1
Baeyens, WR; De Beer, T; Dilinuer, M; Fei, GT; Ouyang, J; Wang, Y; Zhou, S	1
Gilbert, EM; Lombardi, WL; Macgregor, J; Munger, M; Stoddard, GP; Zebrack, JS	1

Reviews

2 review(s) available for terbutaline and metoprolol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
A convenient method for local drug administration at predefined sites in the entire gastrointestinal tract: experiences from 13 phase I studies. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2007, Volume: 30, Issue:5 Topics: Adrenergic Agents; Adult; Area Under Curve; Biological Availability; Clinical Trials, Phase I as Topic; Female; Gastrointestinal Tract; Gastrointestinal Transit; Humans; Intestinal Absorption; Intubation, Gastrointestinal; Male; Metoprolol; Patient Dropouts; Terbutaline	2007

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

A convenient method for local drug administration at predefined sites in the entire gastrointestinal tract: experiences from 13 phase I studies.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2007, Volume: 30, Issue:5

Topics: Adrenergic Agents; Adult; Area Under Curve; Biological Availability; Clinical Trials, Phase I as Topic; Female; Gastrointestinal Tract; Gastrointestinal Transit; Humans; Intestinal Absorption; Intubation, Gastrointestinal; Male; Metoprolol; Patient Dropouts; Terbutaline

2007

Trials

18 trial(s) available for terbutaline and metoprolol

Article	Year
Differences in metabolic responses to beta-adrenergic stimulation after propranolol or metoprolol administration. Acta medica Scandinavica, 1979, Volume: 205, Issue:3 Topics: Adult; Blood Glucose; Fatty Acids, Nonesterified; Glycerol; Hemodynamics; Humans; Insulin; Isoproterenol; Male; Metoprolol; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sodium Chloride; Terbutaline	1979
Is metoprolol CR/ZOK more selective than conventional metoprolol and atenolol? Journal of clinical pharmacology, 1990, Volume: 30, Issue:S2 Topics: Adult; Atenolol; Blood Glucose; Delayed-Action Preparations; Exercise; Female; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Potassium; Random Allocation; Receptors, Adrenergic, beta; Single-Blind Method; Tablets; Terbutaline	1990
A nonsteady-state agonist antagonist interaction model using plasma potassium concentrations to quantify the beta-2 selectivity of beta blockers. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:1 Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Male; Metoprolol; Models, Biological; Oxprenolol; Potassium; Receptors, Adrenergic, beta; Terbutaline	1989
Controlled-release metoprolol compared with atenolol in asthmatic patients: interaction with terbutaline. European journal of clinical pharmacology, 1988, Volume: 33 Suppl Topics: Adult; Aged; Asthma; Atenolol; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Forced Expiratory Volume; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Random Allocation; Receptors, Adrenergic, beta; Respiratory Muscles; Terbutaline; Ventilation-Perfusion Ratio	1988
Combined beta 1-adrenoceptor blockade and/or beta 2- or beta 1/2 adrenoceptor stimulation as treatment of essential hypertension. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4 Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Metaproterenol; Metoprolol; Middle Aged; Receptors, Adrenergic, beta; Terbutaline	1988
Beta adrenergic influence on oesophageal peristalsis in man. Gut, 1986, Volume: 27, Issue:3 Topics: Adrenergic beta-Agonists; Adult; Esophagus; Female; Humans; Male; Metoprolol; Middle Aged; Peristalsis; Practolol; Prenalterol; Pressure; Propranolol; Terbutaline	1986
Beta-adrenoceptor stimulating and blocking agents in essential hypertension: single and combined therapy with terbutaline and metoprolol. International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:10 Topics: Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Norepinephrine; Physical Exertion; Renin; Terbutaline	1987
Ventilatory effects of long-term treatment with pindolol and metoprolol in hypertensive patients with chronic obstructive lung disease. British journal of clinical pharmacology, 1985, Volume: 20, Issue:3 Topics: Adult; Female; Forced Expiratory Volume; Humans; Hypertension; Lung Diseases, Obstructive; Male; Metoprolol; Middle Aged; Pindolol; Respiration; Terbutaline	1985
Beta-adrenoceptor blockers and terbutaline in patients with chronic obstructive lung disease. Effects and interaction after oral administration. Chest, 1980, Volume: 78, Issue:5 Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lung Diseases, Obstructive; Male; Metoprolol; Middle Aged; Propranolol; Respiratory Function Tests; Terbutaline	1980
Comparative study of the ventilatory effects of three beta 1-selective blocking agents in asthmatic patients. European journal of clinical pharmacology, 1981, Volume: 20, Issue:6 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Asthma; Atenolol; Bronchi; Clinical Trials as Topic; Heart Rate; Humans; Male; Metoprolol; Pulmonary Ventilation; Respiration; Terbutaline; Vital Capacity	1981
Inhibition of antipyrine metabolism by beta-adrenoceptor antagonists. British journal of clinical pharmacology, 1981, Volume: 12, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Antipyrine; Depression, Chemical; Humans; Kinetics; Male; Metoprolol; Propranolol; Terbutaline	1981
Pafenolol, a highly selective beta 1-adrenoceptor-antagonist, in asthmatic patients: interaction with terbutaline. Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:1 Topics: Adrenergic beta-Antagonists; Aged; Asthma; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Drug Interactions; Female; Heart Rate; Humans; Male; Maximal Expiratory Flow Rate; Metoprolol; Middle Aged; Propanolamines; Random Allocation; Terbutaline	1983
[Terbutaline-induced metabolic responses after propranolol and metoprolol]. Wiener klinische Wochenschrift, 1982, Dec-24, Volume: 94, Issue:24 Topics: Adult; Blood Pressure; Drug Antagonism; Fatty Acids, Nonesterified; Female; Glucose; Glycerol; Heart Rate; Hemodynamics; Humans; Lactates; Male; Metoprolol; Potassium; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Terbutaline	1982
Intravenous terbutaline and simultaneous beta 1-blockade for advanced premature labor. American journal of obstetrics and gynecology, 1983, Dec-15, Volume: 147, Issue:8 Topics: Administration, Oral; Adult; Birth Weight; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Gestational Age; Heart Rate; Humans; Infant, Newborn; Infusions, Parenteral; Metoprolol; Obstetric Labor, Premature; Pregnancy; Terbutaline	1983
Cardioselectivity of atenolol and metoprolol. A study in asthmatic patients. European journal of respiratory diseases, 1981, Volume: 62, Issue:6 Topics: Adult; Aged; Asthma; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory Volume; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Muscle Contraction; Physical Exertion; Propanolamines; Terbutaline; Vital Capacity	1981
Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients. European journal of clinical pharmacology, 1982, Volume: 23, Issue:3 Topics: Acebutolol; Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory Volume; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Peak Expiratory Flow Rate; Propanolamines; Respiration; Terbutaline	1982
Ventilatory effects of ordinary and slow-release tablets of metoprolol in asthmatic patients. European journal of respiratory diseases, 1981, Volume: 62, Issue:3 Topics: Adolescent; Adult; Asthma; Delayed-Action Preparations; Female; Forced Expiratory Volume; Heart Rate; Humans; Male; Metoprolol; Peak Expiratory Flow Rate; Propanolamines; Respiration; Terbutaline; Vital Capacity	1981
Beta-receptor selectivity of carvedilol and metoprolol succinate in patients with heart failure (SELECT trial): a randomized dose-ranging trial. Pharmacotherapy, 2009, Volume: 29, Issue:8 Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Blood Glucose; Carbazoles; Carvedilol; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Potassium; Propanolamines; Terbutaline	2009

Other Studies

60 other study(ies) available for terbutaline and metoprolol

Article	Year
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes. Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7 Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet	1998
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. British journal of pharmacology, 2005, Volume: 144, Issue:3 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3	2005
Exploring the role of different drug transport routes in permeability screening. Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2 Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay. Bioorganic & medicinal chemistry letters, 2010, Jan-01, Volume: 20, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
In vitro characterization of human peptide transporter hPEPT1 interactions and passive permeation studies of short cationic antimicrobial peptides. Journal of medicinal chemistry, 2011, Apr-14, Volume: 54, Issue:7 Topics: Animals; Antimicrobial Cationic Peptides; Bacteria; Humans; Microbial Sensitivity Tests; Peptide Transporter 1; Permeability; Phospholipids; Protein Binding; Symporters	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Acute hypotensive effect of combined beta1-adrenoceptor blockade and beta2-adrenoceptor stimulation in spontaneously hypertensive rats (SHR). European journal of pharmacology, 1977, Jan-07, Volume: 41, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Depression, Chemical; Drug Interactions; Heart Rate; Hypertension; Metoprolol; Propranolol; Rats; Terbutaline	1977
Tremor caused by sympathomimetics is mediated by beta2-adrenoreceptors. Scandinavian journal of respiratory diseases, 1977, Volume: 58, Issue:1 Topics: Blood Pressure; Heart Rate; Humans; Informed Consent; Metoprolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sympathomimetics; Terbutaline; Tremor	1977
Broncho-and cardioselective beta-receptor active drugs in the treatment of asthmatic patients. Clinical studies of effects and side effects of terbutaline, practolol and metoprolol. Scandinavian journal of respiratory diseases. Supplementum, 1977, Volume: 97 Topics: Administration, Oral; Asthma; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Injections, Subcutaneous; Metoprolol; Muscle Cramp; Practolol; Propanolamines; Terbutaline; Tremor	1977
Regional difference in the response mediated by beta 1-adrenoceptor subtype in bovine cerebral arteries. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:3 Topics: Adrenergic beta-Agonists; Animals; Cattle; Cerebral Arteries; Colforsin; Dose-Response Relationship, Drug; Homeostasis; Isoproterenol; Metoprolol; Norepinephrine; Receptors, Adrenergic, beta; Terbutaline	1992
Quantification of metoprolol beta 2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamic modelling. Pulmonary pharmacology, 1992, Volume: 5, Issue:1 Topics: Adult; Asthma; Female; Forced Expiratory Volume; Humans; Male; Metoprolol; Middle Aged; Potassium; Terbutaline	1992
Effects of beta-adrenergic agonists on splanchnic vascular volume and cardiac output. The American journal of physiology, 1991, Volume: 261, Issue:5 Pt 2 Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Blood Volume; Cardiac Output; Denervation; Dogs; Female; Heart Rate; Isoproterenol; Male; Metoprolol; Muscle, Smooth, Vascular; Phenoxybenzamine; Pressoreceptors; Receptors, Adrenergic, beta; Splanchnic Circulation; Splenectomy; Terbutaline	1991
The effect of adrenergic agonists and antagonists on cysteine-proteinase inhibitor (cystatin) in rat saliva. Archives of oral biology, 1991, Volume: 36, Issue:8 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Blotting, Western; Cysteine Proteinase Inhibitors; Dobutamine; Electrophoresis, Polyacrylamide Gel; Female; Isoproterenol; Methamphetamine; Methoxamine; Metoprolol; Norepinephrine; Propanolamines; Propranolol; Radioimmunoassay; Rats; Rats, Inbred Strains; Salivary Proteins and Peptides; Terbutaline	1991
Debrisoquine phenotype and the pharmacokinetics and beta-2 receptor pharmacodynamics of metoprolol and its enantiomers. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3 Topics: Administration, Oral; Adult; Debrisoquin; Drug Interactions; Female; Humans; Male; Metoprolol; Phenotype; Receptors, Adrenergic, beta; Stereoisomerism; Terbutaline	1991
The actions of tulobuterol on isolated preparations of gravid human myometrium. Clinical and experimental pharmacology & physiology, 1990, Volume: 17, Issue:9 Topics: Adrenergic beta-Agonists; Electric Stimulation; Epinephrine; Female; Humans; In Vitro Techniques; Isoproterenol; Metoprolol; Molecular Structure; Pregnancy; Terbutaline; Uterine Contraction	1990
Beta-2 adrenoceptor control of the venous circulation in intact dogs. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3 Topics: Animals; Blood Circulation; Blood Volume; Dogs; Metoprolol; Receptors, Adrenergic, beta; Splenectomy; Terbutaline; Vascular Resistance; Veins	1987
Beta-2 adrenergic responses to tulobuterol in airway smooth muscle, vascular smooth muscle and adrenergic nerves. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:1 Topics: Adrenergic Fibers; Animals; Bronchi; Coronary Vessels; Dogs; Guinea Pigs; Heart Atria; Metoprolol; Muscle, Smooth; Muscle, Smooth, Vascular; Propanolamines; Receptors, Adrenergic, beta; Saphenous Vein; Terbutaline; Trachea	1988
Subtypes of beta adrenergic receptors mediating pigment dispersion in chromatophores of the medaka, Oryzias latipes. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1985, Volume: 81, Issue:2 Topics: Albuterol; Animals; Atenolol; Cell Aggregation; Chromatophores; Denervation; Epinephrine; Fishes; Kinetics; Melanophores; Metoprolol; Norepinephrine; Pigments, Biological; Receptors, Adrenergic, beta; Skin; Terbutaline	1985
Action of agonists and antagonists on adrenergic receptors in isolated porcine coronary arteries. Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:7 Topics: Adrenergic beta-Antagonists; Animals; Coronary Vessels; Dobutamine; Ephedrine; Female; In Vitro Techniques; Male; Metoprolol; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Receptors, Adrenergic; Swine; Terbutaline	1985
Beta adrenergic influence on esophageal and colonic motility in man. Scandinavian journal of gastroenterology. Supplement, 1985, Volume: 116 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Colon; Colonic Diseases, Functional; Esophagus; Female; Gastrointestinal Motility; Humans; Male; Manometry; Metoprolol; Middle Aged; Parasympatholytics; Practolol; Prenalterol; Propranolol; Sincalide; Terbutaline	1985
Beta-adrenergic control of motility in the rat colon. I. Evidence for functional separation of the beta 1- and beta 2-adrenoceptor-mediated inhibition of colon activity. Gastroenterology, 1986, Volume: 90, Issue:2 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colon; Gastrointestinal Motility; Isoproterenol; Male; Metoprolol; Muscle, Smooth; Practolol; Prenalterol; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Sympathectomy; Terbutaline; Tetrodotoxin	1986
Effects of dobutamine and terbutaline on the secretion of glycoproteins from the acinar cells of the rat submandibular gland. Japanese journal of pharmacology, 1988, Volume: 47, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Dobutamine; Electrophoresis, Polyacrylamide Gel; Glycoproteins; Male; Metoprolol; Propanolamines; Rats; Rats, Inbred Strains; Saliva; Submandibular Gland; Terbutaline	1988
Characterization of functional beta-adrenoceptor subtypes in rabbit urinary bladder smooth muscle. The Tohoku journal of experimental medicine, 1986, Volume: 149, Issue:4 Topics: Animals; Butoxamine; Dobutamine; Isoproterenol; Male; Metoprolol; Muscle Contraction; Muscle, Smooth; Propranolol; Rabbits; Receptors, Adrenergic, beta; Terbutaline; Urinary Bladder	1986
Adrenergic drugs and intraocular pressure: suppression of ocular hypertension induced by water loading. Experimental eye research, 1980, Volume: 30, Issue:1 Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Dobutamine; Ephedrine; Epinephrine; Intraocular Pressure; Isoproterenol; Male; Metoprolol; Propranolol; Pupil; Rabbits; Sympathomimetics; Terbutaline; Timolol; Water	1980
Effects of selective and non-selective beta-adrenergic agents on insulin secretion in vivo. European journal of pharmacology, 1981, Apr-24, Volume: 71, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Butoxamine; Carbachol; Dose-Response Relationship, Drug; Female; Glucose; Insulin; Insulin Secretion; Isoproterenol; Metoprolol; Mice; Propanolamines; Propranolol; Terbutaline; Thiazoles	1981
Beta adrenergic effects on ciliary epithelial permeability, aqueous humor formation and pseudofacility in the normal and sympathectomized rabbit eye. Current eye research, 1981, Volume: 1, Issue:7 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Butoxamine; Ciliary Body; In Vitro Techniques; Intraocular Pressure; Metoprolol; Permeability; Propanolamines; Rabbits; Sympathectomy; Terbutaline; Thiazoles	1981
Characterization of the beta-adrenergic inhibition of motility in cat colon strips. European journal of pharmacology, 1982, Jan-08, Volume: 77, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cats; Colon; Female; Gastrointestinal Motility; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Practolol; Prenalterol; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, beta; Terbutaline; Tetrodotoxin	1982
Basic pharmacological properties of prenalterol. Acta medica Scandinavica. Supplementum, 1982, Volume: 659 Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Cats; Cyclic AMP; Dose-Response Relationship, Drug; Epinephrine; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Metoprolol; Myocardial Contraction; Papillary Muscles; Phentolamine; Practolol; Prenalterol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Terbutaline; Vascular Resistance	1982
The importance of an intact sympathetic innervation for the differentiation of the beta-adrenoceptor subtypes in the rat parotid gland. Acta physiologica Scandinavica, 1982, Volume: 115, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Dihydroalprenolol; Ephedrine; Metoprolol; Parotid Gland; Practolol; Prenalterol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Sympathectomy; Terbutaline	1982
Studies of catecholamine effect on cyclic AMP in human cultured thyroid cells: their interaction with thyrotrophin receptor. Acta endocrinologica, 1983, Volume: 102, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cells, Cultured; Cyclic AMP; DNA; Epinephrine; Humans; Isoproterenol; Metoprolol; Norepinephrine; Practolol; Prenalterol; Receptors, Cell Surface; Receptors, Thyrotropin; Terbutaline; Thyroid Gland; Thyrotropin	1983
Effects of beta 1-adrenoceptor stimulation and blockade studied in asthmatic airways. European journal of respiratory diseases. Supplement, 1984, Volume: 135 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Asthma; Humans; Metoprolol; Practolol; Prenalterol; Propanolamines; Receptors, Adrenergic, beta; Tachycardia; Terbutaline	1984
Beta 1-adrenoceptor mediated salivary gland enlargement in the rat. Experientia, 1984, Aug-15, Volume: 40, Issue:8 Topics: Adrenergic beta-Agonists; Animals; Female; Metoprolol; Organ Size; Parotid Gland; Practolol; Prenalterol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Submandibular Gland; Terbutaline	1984
Beta 1- and beta 2-adrenoceptor-mediated secretion of amylase from incubated rat parotid gland. Acta physiologica Scandinavica, 1984, Volume: 120, Issue:3 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amylases; Animals; Ephedrine; Female; Metoprolol; Norepinephrine; Parotid Gland; Practolol; Prenalterol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Terbutaline	1984
Modulation by beta-adrenoreceptors of spontaneous contractions of rat urinary bladder. Journal of autonomic pharmacology, 1982, Volume: 2, Issue:4 Topics: Animals; Hexamethonium Compounds; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Muscle Contraction; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Terbutaline; Urinary Bladder	1982
Ventilatory and haemodynamic effects of beta 1-selective and beta 2-selective stimulation in asthmatic patients. European journal of respiratory diseases. Supplement, 1984, Volume: 135 Topics: Asthma; Blood Pressure; Heart Rate; Humans; Metoprolol; Practolol; Prenalterol; Receptors, Adrenergic, beta; Terbutaline	1984
Effect of beta-adrenergic agonists on apnea reflexes in newborn lambs. Pediatric research, 1983, Volume: 17, Issue:3 Topics: Albuterol; Animals; Animals, Newborn; Apnea; Blood Circulation; Blood Pressure; Electric Stimulation; Fenoterol; Heart Rate; Laryngeal Nerves; Metoprolol; Propranolol; Reflex; Respiratory Center; Sheep; Terbutaline; Vascular Resistance	1983
Demonstration of an in vivo functional beta 3-adrenoceptor in man. The Journal of clinical investigation, 1995, Volume: 95, Issue:5 Topics: Adipose Tissue; Adrenergic beta-Antagonists; Adult; Analysis of Variance; Animals; Body Temperature Regulation; Cells, Cultured; Dobutamine; Female; Humans; Isoproterenol; Kinetics; Lipolysis; Male; Mammals; Metoprolol; Microdialysis; Middle Aged; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reference Values; Regional Blood Flow; Terbutaline; Time Factors	1995
Cardiovascular teratogenicity of terbutaline and ritodrine in the chick embryo. American journal of obstetrics and gynecology, 1994, Volume: 171, Issue:2 Topics: Animals; Butoxamine; Chick Embryo; Dose-Response Relationship, Drug; Heart Defects, Congenital; Metoprolol; Receptors, Adrenergic, beta; Ritodrine; Terbutaline	1994
Interaction between substance P and beta-adrenergic agonists in the modulation of the secretion of fluid and protein by the rat submandibular gland. The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:3 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dobutamine; Drug Interactions; Injections, Intravenous; Isoproterenol; Male; Metoprolol; Propanolamines; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Saliva; Submandibular Gland; Substance P; Terbutaline	1998
Sympathotropic drugs and the distribution of 99mTc-hydroxymethylene diphosphonate. Experimental studies in the mouse. Acta radiologica (Stockholm, Sweden : 1987), 1999, Volume: 40, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Bone and Bones; Contrast Media; Ephedrine; Male; Metoprolol; Mice; Mice, Inbred Strains; Propranolol; Radionuclide Imaging; Sotalol; Sympathomimetics; Technetium Tc 99m Medronate; Terbutaline; Tissue Distribution	1999
Synergistic interaction of catecholamine hormones and Mycobacterium avium results in the induction of interleukin-10 mRNA expression by murine peritoneal macrophages. Journal of neuroimmunology, 1999, Jan-01, Volume: 93, Issue:1-2 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Antigens, Bacterial; Bucladesine; Cyclic AMP; Dobutamine; Drug Synergism; Epinephrine; Gene Expression; Interleukin-10; Macrophages, Peritoneal; Male; Metoprolol; Mice; Mice, Inbred BALB C; Mycobacterium avium; Phentolamine; Propanolamines; Propranolol; RNA, Messenger; Terbutaline	1999
Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport. Journal of pharmaceutical sciences, 2000, Volume: 89, Issue:1 Topics: Antipyrine; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Carrier Proteins; Cell Membrane Permeability; Cellular Senescence; Coculture Techniques; Furosemide; HT29 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Ketoprofen; Mannitol; Metoprolol; Microscopy, Electron; Piroxicam; Reproducibility of Results; Terbutaline	2000
Simultaneous separation of eight beta-adrenergic drugs using titanium dioxide nanoparticles as additive in capillary electrophoresis. Electrophoresis, 2008, Volume: 29, Issue:11 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Atenolol; Buffers; Celiprolol; Clenbuterol; Electroosmosis; Electrophoresis, Capillary; Fenoterol; Hydrogen-Ion Concentration; Isoproterenol; Metal Nanoparticles; Metoprolol; Propranolol; Reproducibility of Results; Terbutaline; Titanium; Uncertainty	2008