Page last updated: 2024-09-02

tephrosin and rotenone

tephrosin has been researched along with rotenone in 24 studies

Compound Research Comparison

Studies
(tephrosin)
Trials
(tephrosin)
Recent Studies (post-2010)
(tephrosin)
Studies
(rotenone)
Trials
(rotenone)
Recent Studies (post-2010) (rotenone)
300154,40761,648

Protein Interaction Comparison

ProteinTaxonomytephrosin (IC50)rotenone (IC50)
Bile salt export pumpHomo sapiens (human)8
NADH-ubiquinone oxidoreductase chain 1Bos taurus (cattle)0.015
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrialBos taurus (cattle)0.0051
Cytochrome P450 2C19Homo sapiens (human)3.6486
5-hydroxytryptamine receptor 6Homo sapiens (human)0.87
Acyl carrier protein, mitochondrialBos taurus (cattle)0.0051

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's0 (0.00)18.2507
2000's7 (29.17)29.6817
2010's13 (54.17)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Ashack, RJ; Goodman, FR; Malek, RS; McCarty, LP; Peet, NP1
Chiba, N; Ohsaki, A; Takashima, J; Yoneda, K1
Andriantsiferana, R; Cao, S; Kingston, DG; Miller, JS; Rasamison, VE; Schilling, JK1
Asao, Y; Matsuda, H; Miyagawa, K; Nakashima, S; Takayama, S; Xu, F; Yoshida, K; Yoshikawa, M1
Gao, S; Gunatilaka, AA; Valeriote, FA; Xu, YM1
Amoah, BA; Belmain, SR; Kamanula, JF; Nyirenda, SP; Stevenson, PC1
Bueno Pérez, L; Chai, HB; Kinghorn, AD; Lantvit, DD; Li, J; Lucas, DM; Ninh, TN; Pan, L; Soejarto, DD; Swanson, SM1
Belofsky, G; Brown, M; Cardenas-Garcia, B; Chen, X; Deardorff, K; Dondji, B; Ferreira, D; Fulkerson, S; Gény, C; Jones, K; McCornack, J; McNutt, S; Ray, W; Winterstein, E1
Bridges, HR; Hirst, J; Kidd, SL; Mateu, N; Osberger, TJ; Russell, DA; Serreli, R; Sore, HF; Spring, DR1
Derese, S; Heydenreich, M; Midiwo, JO; Peter, MG; Yenesew, A1
Li, S; Wu, J; Xu, LR; Zhang, S1
Chen, L; Fu, A; Li, Y; Luo, H; Luo, Y; Peng, A; Shi, J; Song, H; Tang, M; Wei, Y; Xu, Y; Ye, H1
Chang, YC; Chen, IS; Chen, JJ; Cheng, LY; Cho, JY; Chou, TH; Hwang, TL; Lee, TH; Wang, TC1
Choi, S; Choi, Y; Dat, NT; Hwangbo, C; Lee, JH; Lee, JJ1
Barluenga, S; Beebe, K; Garcia, J; Neckers, L; Winssinger, N1
Fang, YC; Li, J; Wang, CY; Wang, XL1
Choi, Y; Lee, JH1
Diao, Y; Jia, Y; Qu, X; Wang, S; Zhang, Z1
Ciardiello, JJ; Freudenreich, JJ; Russell, DA; Sore, HF; Spring, DR1
Awouafack, MD; Kodama, T; Mba Nguekeu, YM; Morita, H; Nguedia Lando, MR; Tane, P1
Huang, X; Tian, H; Yang, J1
Li, W; Lin, A; Wang, G; Xu, F; Xu, J; Xu, S; Yao, H1
Hurem, S; Kyewalyanga, MS; Lyche, JL; Mmochi, AJ; Msuya, FE; Said, AH; Sandvik, M; Solhaug, A1
Aali, E; Darzi, S; Elahian, F; Mirzaei, SA; Peymani, A; Pishkhan Dibazar, S; Rahmani, B; Shakeri Chaleshtori, L; Shirian, S1

Other Studies

24 other study(ies) available for tephrosin and rotenone

ArticleYear
Evaluation of rotenone and related compounds as antagonists of slow-reacting substance of anaphylaxis.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:9

    Topics: Acetylcholine; Anaphylaxis; Animals; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Rotenone; Serotonin Antagonists; SRS-A

1980
Derrisin, a new rotenoid from Derris malaccensis plain and anti-Helicobacter pylori activity of its related constituents.
    Journal of natural products, 2002, Volume: 65, Issue:4

    Topics: Anti-Bacterial Agents; Drugs, Chinese Herbal; Helicobacter pylori; Heterocyclic Compounds, 4 or More Rings; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plants, Medicinal

2002
Cytotoxic compounds from Mundulea chapelieri from the Madagascar Rainforest.
    Journal of natural products, 2004, Volume: 67, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Fabaceae; Female; Flavonoids; Humans; Inhibitory Concentration 50; Madagascar; Molecular Structure; Plants, Medicinal; Tumor Cells, Cultured

2004
Rotenoids and flavonoids with anti-invasion of HT1080, anti-proliferation of U937, and differentiation-inducing activity in HL-60 from Erycibe expansa.
    Bioorganic & medicinal chemistry, 2007, Feb-01, Volume: 15, Issue:3

    Topics: Cell Differentiation; Cell Proliferation; Convolvulaceae; Enzyme Precursors; Fibrosarcoma; Flavonoids; Gelatinases; HL-60 Cells; Humans; Matrix Metalloproteinase 9; Metalloendopeptidases; Neoplasm Invasiveness; Plant Extracts; Rotenone; Tumor Cells, Cultured; U937 Cells

2007
Pierreiones A-D, solid tumor selective pyranoisoflavones and other cytotoxic constituents from Antheroporum pierrei.
    Journal of natural products, 2011, Apr-25, Volume: 74, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Isoflavones; Mice; Molecular Structure; National Cancer Institute (U.S.); Nuclear Magnetic Resonance, Biomolecular; Plant Leaves; Plant Stems; Pyrans; Thailand; United States

2011
Highly variable insect control efficacy of Tephrosia vogelii chemotypes.
    Journal of agricultural and food chemistry, 2012, Oct-10, Volume: 60, Issue:40

    Topics: Africa; Animals; Coleoptera; Flavonoids; Insect Control; Insecticides; Plant Leaves; Rotenone; Tephrosia; Weevils

2012
Bioactive constituents of Indigofera spicata.
    Journal of natural products, 2013, Aug-23, Volume: 76, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Female; Flavanones; HT29 Cells; Humans; Indigofera; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Vietnam

2013
Phenolic Metabolites of Dalea ornata Affect Both Survival and Motility of the Human Pathogenic Hookworm Ancylostoma ceylanicum.
    Journal of natural products, 2016, 09-23, Volume: 79, Issue:9

    Topics: Albendazole; Ancylostoma; Ancylostomatoidea; Ancylostomiasis; Animals; Anthelmintics; Cricetinae; Disease Models, Animal; Disease Resistance; Fabaceae; Humans; Mebendazole; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenols; Plant Components, Aerial; Rosaceae; Saxifragaceae; Spleen

2016
Hydroxylated Rotenoids Selectively Inhibit the Proliferation of Prostate Cancer Cells.
    Journal of natural products, 2020, 06-26, Volume: 83, Issue:6

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Cattle; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Electron Transport Complex I; Humans; Male; Mitochondrial Membranes; Molecular Structure; Prostatic Neoplasms; Rotenone; Uncoupling Agents

2020
Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti.
    Pest management science, 2003, Volume: 59, Issue:10

    Topics: Aedes; Animals; Chromones; Dose-Response Relationship, Drug; Insecticides; Larva; Millettia; Molecular Structure; Plant Extracts; Pyrans; Rotenone; Seeds

2003
[Rotenoids from Derris trifoliata].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2007, Volume: 30, Issue:6

    Topics: Chromones; Derris; Plant Components, Aerial; Plants, Medicinal; Rotenone

2007
Preparative isolation and purification of three rotenoids and one isoflavone from the seeds of Millettia pachycarpa Benth by high-speed counter-current chromatography.
    Journal of chromatography. A, 2008, Jan-18, Volume: 1178, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Chromones; Countercurrent Distribution; Isoflavones; Magnetic Resonance Spectroscopy; Millettia; Pyrans; Rotenone; Seeds; Spectrometry, Mass, Electrospray Ionization

2008
Phthalides from Pittosporum illicioides var. illicioides with inhibitory activity on superoxide generation and elastase release by neutrophils.
    Journal of natural products, 2008, Volume: 71, Issue:10

    Topics: Benzofurans; Cytochalasin B; Humans; Inhibitory Concentration 50; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nuclear Magnetic Resonance, Biomolecular; Pancreatic Elastase; Plant Roots; Plants, Medicinal; Rosales; Rotenone; Superoxides; Taiwan

2008
Tephrosin induces internalization and degradation of EGFR and ErbB2 in HT-29 human colon cancer cells.
    Cancer letters, 2010, Jul-01, Volume: 293, Issue:1

    Topics: Apoptosis; Blotting, Western; Caspases; Cell Death; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Epidermal Growth Factor; ErbB Receptors; Female; HCT116 Cells; HT29 Cells; Humans; Male; Neuregulin-1; Phosphorylation; Receptor, ErbB-2; Receptor, ErbB-3; Rotenone

2010
Concise modular asymmetric synthesis of deguelin, tephrosin and investigation into their mode of action.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2010, Aug-23, Volume: 16, Issue:32

    Topics: Animals; Biological Products; HSP90 Heat-Shock Proteins; Mice; Molecular Structure; Rotenone

2010
Tephrosin-induced autophagic cell death in A549 non-small cell lung cancer cells.
    Journal of Asian natural products research, 2010, Volume: 12, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HSP90 Heat-Shock Proteins; Humans; Membrane Potential, Mitochondrial; Microscopy, Confocal; Molecular Structure; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Rotenone

2010
The combination of tephrosin with 2-deoxy-D-glucose enhances the cytotoxicity via accelerating ATP depletion and blunting autophagy in human cancer cells.
    Cancer biology & therapy, 2011, Dec-01, Volume: 12, Issue:11

    Topics: Adenosine Triphosphate; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Deoxyglucose; Elongation Factor 2 Kinase; Enzyme Activation; Humans; Intracellular Space; Neoplasms; Rotenone

2011
Evaluation of anti-bacterial and wound healing activity of the fruits of Amorpha fruticosa L.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2013, Volume: 10, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Fabaceae; Fibroblasts; Flavonoids; Fruit; Male; Mice; Phytotherapy; Plant Preparations; Rats; Rats, Sprague-Dawley; Rotenone; Wound Healing; Wounds, Penetrating

2013
Stereocontrolled semi-syntheses of deguelin and tephrosin.
    Organic & biomolecular chemistry, 2017, Feb-21, Volume: 15, Issue:7

    Topics: Molecular Conformation; Rotenone; Stereoisomerism

2017
A kaempferol triglycoside from Tephrosia preussii Taub. (Fabaceae).
    Natural product research, 2017, Volume: 31, Issue:21

    Topics: Anti-Bacterial Agents; Betulinic Acid; Drug Evaluation, Preclinical; Glycosides; Kaempferols; Klebsiella pneumoniae; Magnetic Resonance Spectroscopy; Pentacyclic Triterpenes; Plant Extracts; Plant Leaves; Rotenone; Sitosterols; Tephrosia; Triterpenes

2017
Tephrosin attenuates sepsis induced acute lung injury in rats by impeding expression of ICAM-1 and MIP-2.
    Microbial pathogenesis, 2018, Volume: 117

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Cecum; Chemokine CXCL2; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Intercellular Adhesion Molecule-1; Lung; Lung Injury; Lymphocyte Count; Male; Neutrophils; Protective Agents; Rats; Rats, Sprague-Dawley; Rotenone; Sepsis

2018
Concise Total Synthesis of (±)-Deguelin and (±)-Tephrosin Using a Vinyl Iodide as a Key Building Block.
    Journal of natural products, 2018, 04-27, Volume: 81, Issue:4

    Topics: Biological Products; Hydroxylation; Rotenone; Stereoisomerism; Vinyl Compounds

2018
Isolation of the Tephrosia vogelii extract and rotenoids and their toxicity in the RTgill-W1 trout cell line and in zebrafish embryos.
    Toxicon : official journal of the International Society on Toxinology, 2020, Volume: 183

    Topics: Animals; Cell Line; Embryo, Nonmammalian; Insecticides; Plant Extracts; Rotenone; Tephrosia; Trout; Zebrafish

2020
Improvement of cytotoxicity of mitoxantrone and daunorubicin by candidone, tephrosin, and bavachinin.
    Molecular biology reports, 2021, Volume: 48, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Cytotoxins; Daunorubicin; Female; Flavonoids; Humans; MCF-7 Cells; Mitoxantrone; Neoplasm Proteins; Rotenone; Stomach Neoplasms

2021