tenulin has been researched along with cyclopentenone* in 1 studies
1 other study(ies) available for tenulin and cyclopentenone
| Article | Year |
|---|---|
Explaining photodermatosis: cyclopentenone vs. alpha-methylene-gamma-lactone natural products.
The possible role of cyclopentenone-containing sesquiterpene lactones in the cause of photochemical chronic actinic dermatitis (CAD) is examined in light of recent reports that the alpha-methylene-gamma-lactone group of these natural products forms 2+2 photoadducts with the DNA base thymine. Neither cyclopentenone nor tenulin (a cyclopentenone-containing sesquiterpene lactone) form such photoadducts with thymine either with sunlight or a UV lamp (300 nm). In contrast, alpha-methylenebutyrolactone readily forms the 2+2 photoadduct with thymine in sunlight. Thus, the photochemical role of the alpha-methylene-gamma-lactone group (rather than cyclopentenone) is strongly implicated in the CAD disease. Topics: Asteraceae; Cyclopentanes; Dermatitis, Photoallergic; DNA Adducts; Humans; Lactones; Plant Extracts; Plants, Medicinal; Sesquiterpenes; Sunlight; Thymine | 2001 |