Page last updated: 2024-08-24

tenofovir and tenofovir diphosphate

tenofovir has been researched along with tenofovir diphosphate in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's27 (54.00)24.3611
2020's23 (46.00)2.80

Authors

AuthorsStudies
Berger, D; Bredeek, UF; Callebaut, C; DeJesus, E; Fordyce, MW; Markowitz, M; Ramanathan, S; Rhee, MS; Ruane, PJ; Yale, K; Zhong, L1
Gao, Y; Katz, DF1
Burns, RN; Chaturvedula, A; Hendrix, CW1
Babusis, D; Hao, J; Lepist, EI; Murakami, E; Park, Y; Ray, AS; Wang, T1
Amara, A; Back, D; Boffito, M; Dickinson, L; Else, L; Higgs, C; Jackson, A; Karolia, Z; Khoo, S; Moyle, G; Yapa, HM1
Amico, KR; Anderson, PL; Bacon, O; Blue, RW; Buchbinder, S; Cardenas, G; Chege, W; Cohen, SE; Coleman, ME; Doblecki-Lewis, S; Elion, R; Estrada, Y; Feaster, DJ; Grant, R; Kolber, MA; Liegler, T; Liu, AY; Matheson, T; Philip, SS; Postle, BS; Rawlings, MK; Trainor, N; Vittinghoff, E1
Callebaut, C; Cox, S; Das, M; Margot, N; McCallister, S; Miller, MD1
Cottrell, ML; Emerson, CW; Garrett, KL; Gay, C; Kashuba, ADM; McCallister, S; Peery, A; Prince, HMA; Rooney, JF; Schauer, A; Sykes, C1
Chen, Q; Jin, X; Ouyang, B; Peng, Y; Sun, J; Wang, G; Zhang, J; Zhen, L; Zhou, F1
Achterbergh, RCA; Anderson, PL; Cornelissen, M; de Bree, GJ; de Vries, HJC; Hoornenborg, E; Jurriaans, S; Kootstra, NA; Prins, JM; Prins, M; Reiss, P; Woittiez, LR1
Bodwell, J; Kashuba, ADM; Patel, MV; Rodriguez-Garcia, M; Shen, Z; Wira, CR1
Bakshi, RP; Breakey, J; Fuchs, EJ; Jois, B; Manohar, M; Marzinke, MA1
Barth, A; Lai, MT; Ma, B; McHale, CM1
Anderson, SM; Chandra, N; Cottrell, M; Doncel, GF; Kashuba, A; Kimble, T; Schwartz, JL; Sykes, C; Thurman, AR; Yousefieh, N1
Anderson, PL; Brainard, DM; Bushman, LR; Castillo-Mancilla, JR; Chung, RT; Fierer, DS; Hughes, MD; Kim, AY; Kiser, JJ; MacBrayne, CE; Marks, KM; Naggie, S; Peters, MG; Seifert, SM1
Balar, B; Dai, JY; Dezzutti, CS; Galaska, B; Hendrix, CW; Justman, JE; Kunjara Na Ayudhya, RP; Levy, L; Marzinke, MA; McGowan, I; Mushamiri, I; Nair, GL; Pan, Z; Piper, JM; Schwartz, JL1
Bensouda, S; Cone, RA; Date, AA; Ensign, LM; Fuchs, EJ; Gumber, S; Hanes, J; Hendrix, C; Hoang, T; Marzinke, M; Ortiz, JO; Rohan, L; Villinger, F; Xiao, P; Young, TW1
Bumpus, NN; Fuchs, EJ; Hendrix, CW; Seneviratne, HK1
Bodwell, J; Patel, MV; Rodriguez-Garcia, M; Shen, Z; Wira, CR1
Abrams, EJ; Brittain, K; Gomba, Y; Hu, NC; Maartens, G; Myer, L; Norman, J; Orrell, C; Phillips, TK; Sinxadi, P; Wiesner, L; Zerbe, A1
Amico, KR; Anderson, PL; Beymer, MR; Bolan, R; Bushman, LR; Goodman-Meza, D; Jordan, WC; Kofron, RM; Landovitz, RJ; Psaros, C; Rooney, JF; Wohl, AR1
Anderson, PL; Bushman, LR; Castillo-Mancilla, JR; Coleman, SS; Coyle, RP; Ellison, L; Gardner, EM; Kiser, JJ; MaWhinney, S; Morrow, M; Zheng, JH2
Anderson, PL; Bacon, O; Buchbinder, SP; Cohen, S; Coleman, ME; Elion, R; Gandhi, M; Glidden, DV; Kolber, MA; Liu, AY; Scott, H; Spinelli, MA; Vittinghoff, E1
Anderson, SM; Doncel, GF; Gajer, P; Marzinke, MA; Ravel, J; Schwartz, JL; Thurman, AR; Yousefieh, N1
Beksinska, M; Brown, TT; Eneh, P; Fowler, MG; Isingel, E; Kabwigu, S; Kaiser, T; Kiweewa Matovu, F; Nakalega, R; Nicol, MR; Staley, C; Sykes, C1
Bumpus, NN; Chaturvedula, A; Fossler, MJ; Goti, V; Haberer, JE; Hendrix, CW; Mallayasamy, S; Marzinke, MA; Sale, M1
Kearney, B; Kolaris, C; Ling, KHJ; Majeed, SR; Tarnowski, T; Xiao, D; Zondlo, S1
Aldern, KA; Beadle, JR; Hostetler, KY; Schooley, RT; Valiaeva, N; Zhang, XQ1
Aizire, J; Brooks, KM; Butler, K; Cababasay, M; Fenton, T; Flynn, PM; Fowler, MG; Kiser, JJ; Mirochnick, M; Siberry, GK1
Bardon, A; Drain, PK; Fernandez Suarez, M; Marshall, L; Sandlin, RD; Sevenler, D; Toner, M1
Anderson, PL; Castillo-Mancilla, J; Chai, PR; Gandhi, M; Haberer, JE; Spinelli, MA1
Anderson, PL; Brooks, KM; Bushman, LR; Castillo-Mancilla, J; Ibrahim, ME; Kiser, JJ; MaWhinney, S; McCallister, S; McHugh, C; Morrow, M; Yager, J1
Anderson, PL; Burke, LA; Bushman, L; Caffrey, M; Ellison, L; Ellsworth, GB; Gulick, RM; Liddle, D; Madhava, M; Mishra, S; O'Neal, C; Stein, J; Wells, MT1
Anderson, PL; Ibrahim, M; MaWhinney, S; Moore, CM; Peterson, S1
Alessi, T; Feldman, PL; Felx, M; Jain, R; Roller, S; Shelton, J; Singh, R; Wang, Y; Yang, B; Zane, D1
Anderson, PL; Bauer, R; Buschman, L; Charreau, I; Cotte, L; Cua, E; Delaugerre, C; Goldwirt, L; Laghzal, A; Liegeon, G; Meyer, L; Molina, JM; Mourah, S; Pialou, G1
Alnouti, Y; Bade, AN; Cobb, DA; Cohen, SM; Deodhar, S; Edagwa, B; Gautam, N; Gendelman, HE; McMillan, J; Shetty, BLD; Smith, N1
Allerton, J; Castillo-Mancilla, J; Hsiao, NY; Hu, NC; Kabanda, S; Lesosky, M; Malaba, TR; Myer, L; Odayar, J; Orrell, C; Phillips, TK; Wiesner, L1
Anderson, PL; Bushman, LR; Castillo-Mancilla, JR; Coleman, SS; Coyle, RP; Ellison, L; Kiser, JJ; MaWhinney, S; Morrow, M; Zheng, JH1
Dobard, C; García-Lerma, JG; Gary, J; Gatto, G; Heneine, W; Holder, A; Johnson, L; Khalil, G; Krovi, A; Li, L; Luecke, E; Massud, I; Mills, P; Mitchell, J; Nishiura, K; Pan, Y; Ruone, S; van der Straten, A1
Liu, W; Yan, B; Yu, S1
Anderson, PL; Bekker, LG; Celum, C; Chirenje, ZM; Delany-Moretlwe, S; Donnell, D; Hosek, S; Marzinke, MA; Mgodi, N; Velloza, J1
Babu, AS; Henny, KD; Pyra, M; Schneider, J; Smith, DK; Townes, A; Wiener, J; Williams, T1
Brady, M; Chen, YQ; Cover, J; Cressey, TR; Drain, P; Duerr, A; Kariithi, E; Mori, K; Obanda, R; Obong'o, C; Okomo, G; Oluoch-Madiang, D; Tapsoba, JD1
Anderson, PL; Brothers, J; Hosek, S; Huhn, G; Keckler, K; Liu, H; Xiong, D1
Amico, KR; Bailey, RC; Graham, SM; Harper, GW; Jadwin-Cakmak, L; Mehta, SD; Ng'ety, G; Obondi, E; Ochieng, E; Okall, DO; Otieno, FO1
Seneviratne, HK1
Canidate, SS; Cook, RL; Gebru, NM; Leeman, RF; Liu, Y; Pavila, E; Schaefer, SE1
Sluis-Cremer, N1

Reviews

2 review(s) available for tenofovir and tenofovir diphosphate

ArticleYear
Approaches to Objectively Measure Antiretroviral Medication Adherence and Drive Adherence Interventions.
    Current HIV/AIDS reports, 2020, Volume: 17, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Emtricitabine; Female; Hair; HIV Infections; Humans; Leukocytes, Mononuclear; Male; Medication Adherence; Monitoring, Ambulatory; Organophosphates; Pre-Exposure Prophylaxis; Tenofovir; Viral Load

2020
Substance Use and Adherence to HIV Pre-Exposure Prophylaxis in Studies Enrolling Men Who Have Sex with Men and Transgender Women: A Systematic Review.
    AIDS and behavior, 2023, Volume: 27, Issue:7

    Topics: Anti-HIV Agents; Female; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Pre-Exposure Prophylaxis; Prospective Studies; Sexual and Gender Minorities; Substance-Related Disorders; Tenofovir; Transgender Persons

2023

Trials

14 trial(s) available for tenofovir and tenofovir diphosphate

ArticleYear
Antiviral activity, safety, and pharmacokinetics/pharmacodynamics of tenofovir alafenamide as 10-day monotherapy in HIV-1-positive adults.
    Journal of acquired immune deficiency syndromes (1999), 2013, Aug-01, Volume: 63, Issue:4

    Topics: Adenine; Adult; Alanine; Anti-Retroviral Agents; Area Under Curve; Dose-Response Relationship, Drug; Fatigue; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nausea; Organophosphates; Organophosphonates; RNA, Viral; Single-Blind Method; Statistics, Nonparametric; Tenofovir; Viral Load; Young Adult

2013
Population pharmacokinetics of tenofovir and tenofovir-diphosphate in healthy women.
    Journal of clinical pharmacology, 2015, Volume: 55, Issue:6

    Topics: Adenine; Administration, Oral; Adolescent; Adult; Antiviral Agents; Biological Availability; Cross-Over Studies; Female; Half-Life; Healthy Volunteers; Humans; Leukocytes, Mononuclear; Middle Aged; Organophosphates; Tenofovir; Vagina; Vaginal Creams, Foams, and Jellies; Women; Young Adult

2015
Plasma Tenofovir, Emtricitabine, and Rilpivirine and Intracellular Tenofovir Diphosphate and Emtricitabine Triphosphate Pharmacokinetics following Drug Intake Cessation.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10

    Topics: Adenine; Adolescent; Adult; Aged; Anti-HIV Agents; Emtricitabine; Female; HIV Infections; Humans; Middle Aged; Organophosphates; Rilpivirine; Tenofovir; Young Adult

2015
Single-dose pharmacokinetics of tenofovir alafenamide and its active metabolite in the mucosal tissues.
    The Journal of antimicrobial chemotherapy, 2017, 06-01, Volume: 72, Issue:6

    Topics: Adenine; Adult; Alanine; Cervix Uteri; Drug Administration Schedule; Epithelial Cells; Female; Gastrointestinal Tract; Humans; Intestinal Mucosa; Leukocytes, Mononuclear; Middle Aged; Mucous Membrane; Organophosphates; Pre-Exposure Prophylaxis; Rectum; Tenofovir; Tissue Distribution; Vagina; Young Adult

2017
Effects of sofosbuvir-based hepatitis C treatment on the pharmacokinetics of tenofovir in HIV/HCV-coinfected individuals receiving tenofovir disoproxil fumarate.
    The Journal of antimicrobial chemotherapy, 2018, 08-01, Volume: 73, Issue:8

    Topics: Adenine; Adult; Antiviral Agents; Benzimidazoles; Coinfection; Drug Interactions; Fluorenes; Hepatitis C; HIV Infections; Humans; Male; Middle Aged; Organophosphates; Ribavirin; Sofosbuvir; Tenofovir; Uridine Monophosphate

2018
Pharmacokinetics and Pharmacodynamics of Tenofovir Reduced-Glycerin 1% Gel in the Rectal and Vaginal Compartments in Women: A Cross-Compartmental Study With Directly Observed Dosing.
    Journal of acquired immune deficiency syndromes (1999), 2018, 06-01, Volume: 78, Issue:2

    Topics: Adenine; Administration, Rectal; Adult; Anti-HIV Agents; Body Fluids; Dose-Response Relationship, Drug; Female; Gels; Glycerol; HIV Infections; Humans; Middle Aged; Organophosphates; Pre-Exposure Prophylaxis; Rectum; Tenofovir; Treatment Outcome; Vagina; Vaginal Creams, Foams, and Jellies; Virus Replication; Young Adult

2018
MALDI Mass Spectrometry Imaging Reveals Heterogeneous Distribution of Tenofovir and Tenofovir Diphosphate in Colorectal Tissue of Subjects Receiving a Tenofovir-Containing Enema.
    The Journal of pharmacology and experimental therapeutics, 2018, Volume: 367, Issue:1

    Topics: Adenine; Colon; Enema; HIV Infections; Humans; Molecular Imaging; Organophosphates; Rectum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tenofovir

2018
Vaginal microbiota and mucosal pharmacokinetics of tenofovir in healthy women using tenofovir and tenofovir/levonorgestrel vaginal rings.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Antiviral Agents; Contraceptive Agents, Hormonal; Contraceptive Devices, Female; Device Removal; Female; Herpes Genitalis; HIV Infections; Humans; Levonorgestrel; Microbiota; Middle Aged; Mucous Membrane; Organophosphates; Tenofovir; Vagina; Young Adult

2019
Antenatal Intracellular Concentrations of Tenofovir Diphosphate and Emtricitabine Triphosphate and Associations Between Tenofovir Diphosphate and Severe Adverse Pregnancy Outcomes: IMPAACT-PROMISE (1077BF) Trial.
    Journal of acquired immune deficiency syndromes (1999), 2020, 02-01, Volume: 83, Issue:2

    Topics: Adenine; Anti-HIV Agents; Case-Control Studies; Chromatography, Liquid; Drug Combinations; Emtricitabine; Female; HIV Infections; Humans; Logistic Models; Lopinavir; Medication Adherence; Organophosphates; Polyphosphates; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Retrospective Studies; Ritonavir; Tenofovir

2020
Intracellular Tenofovir-Diphosphate and Emtricitabine-Triphosphate in Dried Blood Spots Following Tenofovir Alafenamide: The TAF-DBS Study.
    Journal of acquired immune deficiency syndromes (1999), 2020, 07-01, Volume: 84, Issue:3

    Topics: Adenine; Adolescent; Adult; Alanine; Anti-HIV Agents; Cross-Over Studies; Drug Combinations; Emtricitabine; Female; HIV Infections; Humans; Male; Medication Adherence; Middle Aged; Organophosphates; Polyphosphates; Pre-Exposure Prophylaxis; Prospective Studies; Tenofovir; Young Adult

2020
Randomized Pilot Study of an Advanced Smart-Pill Bottle as an Adherence Intervention in Patients With HIV on Antiretroviral Treatment.
    Journal of acquired immune deficiency syndromes (1999), 2021, 01-01, Volume: 86, Issue:1

    Topics: Adenine; Adult; Anti-HIV Agents; Anti-Retroviral Agents; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphates; Pilot Projects; Tenofovir

2021
Estimated pill intake with on-demand PrEP with oral TDF/FTC using TFV-DP concentration in dried blood spots in the ANRS IPERGAY trial.
    The Journal of antimicrobial chemotherapy, 2021, 09-15, Volume: 76, Issue:10

    Topics: Adenine; Adult; Anti-HIV Agents; Emtricitabine; Female; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Sexual and Gender Minorities; Tenofovir

2021
Alignment of PrEP adherence with periods of HIV risk among adolescent girls and young women in South Africa and Zimbabwe: a secondary analysis of the HPTN 082 randomised controlled trial.
    The lancet. HIV, 2022, Volume: 9, Issue:10

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; South Africa; Tenofovir; Young Adult; Zimbabwe

2022
The ATEAM study: Advances in technology to enhance PrEP adherence monitoring (ATEAM) among young men who have sex with men.
    Clinical and translational science, 2022, Volume: 15, Issue:12

    Topics: Adolescent; Adult; Anti-HIV Agents; Cross-Over Studies; Emtricitabine; Female; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Sexual and Gender Minorities; Technology; Tenofovir; Young Adult

2022

Other Studies

34 other study(ies) available for tenofovir and tenofovir diphosphate

ArticleYear
Multicompartmental pharmacokinetic model of tenofovir delivery by a vaginal gel.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Adenine; Anti-HIV Agents; Area Under Curve; Epithelium; Female; HIV Infections; Humans; Models, Statistical; Mucous Membrane; Organophosphates; Organophosphonates; Tenofovir; Vagina; Vaginal Creams, Foams, and Jellies

2013
Implications of efficient hepatic delivery by tenofovir alafenamide (GS-7340) for hepatitis B virus therapy.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:6

    Topics: Adenine; Alanine; Animals; Cells, Cultured; Dogs; Hepatitis B virus; Hepatocytes; Humans; Liver; Male; Organophosphates; Tenofovir

2015
Preexposure Prophylaxis for HIV Infection Integrated With Municipal- and Community-Based Sexual Health Services.
    JAMA internal medicine, 2016, Volume: 176, Issue:1

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Bisexuality; Chlamydia Infections; Community Health Services; District of Columbia; Female; Florida; Gonorrhea; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Middle Aged; Organophosphates; Pre-Exposure Prophylaxis; Prospective Studies; Reproductive Health; San Francisco; Sexual Behavior; Syphilis; Tenofovir; Transgender Persons; Unsafe Sex; Young Adult

2016
Infrequent development of drug resistance in HIV-1-infected treatment-naive subjects after 96 weeks of treatment with elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide or elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate.
    Antiviral therapy, 2017, Volume: 22, Issue:5

    Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cobicistat; Drug Resistance, Viral; Emtricitabine; Genotype; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Organophosphates; Phenotype; Tenofovir

2017
Simultaneous determination of tenofovir alafenamide and its active metabolites tenofovir and tenofovir diphosphate in HBV-infected hepatocyte with a sensitive LC-MS/MS method.
    Journal of pharmaceutical and biomedical analysis, 2017, Nov-30, Volume: 146

    Topics: Adenine; Alanine; Anti-HIV Agents; Cell Line, Tumor; Chromatography, Liquid; DNA Replication; Half-Life; Hep G2 Cells; Hepatocytes; HIV Infections; HIV-1; Humans; Organophosphates; Prodrugs; Tandem Mass Spectrometry; Tenofovir; Virus Replication

2017
Acquisition of wild-type HIV-1 infection in a patient on pre-exposure prophylaxis with high intracellular concentrations of tenofovir diphosphate: a case report.
    The lancet. HIV, 2017, Volume: 4, Issue:11

    Topics: Adenine; Anti-HIV Agents; Emtricitabine; HIV Infections; HIV Seropositivity; HIV-1; Homosexuality, Male; Humans; Lymphogranuloma Venereum; Male; Medication Adherence; Middle Aged; Organophosphates; Pre-Exposure Prophylaxis; RNA, Viral; Tenofovir; Transgender Persons; Urinary Tract Infections

2017
Hormonal Contraceptives Differentially Suppress TFV and TAF Inhibition of HIV Infection and TFV-DP in Blood and Genital Tract CD4+ T cells.
    Scientific reports, 2017, 12-18, Volume: 7, Issue:1

    Topics: Adenine; Adult; Alanine; Anti-HIV Agents; Anti-Retroviral Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; Contraceptive Agents; Contraceptives, Oral, Hormonal; Female; Genitalia, Female; HIV Infections; HIV-1; Humans; Middle Aged; Organophosphates; Progestins; Tenofovir

2017
Short Communication: Specimen Processing Impacts Tissue Tenofovir Pharmacokinetic Measurements.
    AIDS research and human retroviruses, 2018, Volume: 34, Issue:4

    Topics: Adenine; Administration, Oral; Anti-HIV Agents; Biopsy; Culture Media; HIV Infections; Humans; Male; Organophosphates; Pre-Exposure Prophylaxis; Rectum; Specimen Handling; Tenofovir

2018
Establishment of intracellular tenofovir-diphosphate as the key determinant for in vitro-in vivo translation of antiviral efficacy.
    Antiviral research, 2018, Volume: 151

    Topics: Adenine; Alanine; Anti-HIV Agents; Cytoplasm; Databases, Factual; Dose-Response Relationship, Drug; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Meta-Analysis as Topic; Organophosphates; Prodrugs; Tenofovir; Viral Load; Virus Replication

2018
Differences in Local and Systemic TFV PK Among Premenopausal Versus Postmenopausal Women Exposed to TFV 1% Vaginal Gel.
    Journal of acquired immune deficiency syndromes (1999), 2018, 05-01, Volume: 78, Issue:1

    Topics: Adenine; Administration, Intravaginal; Administration, Topical; Anti-HIV Agents; Epithelium; Estradiol; Female; HIV; HIV Infections; Humans; Menstrual Cycle; Mucous Membrane; Organophosphates; Postmenopause; Premenopause; Tenofovir; Time Factors; Vagina; Vaginal Creams, Foams, and Jellies

2018
Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019, Volume: 138

    Topics: Adenine; Administration, Rectal; Alanine; Animals; Anti-HIV Agents; Anti-Infective Agents; Enema; HIV Infections; HIV-1; Homosexuality, Male; Male; Mice; Organophosphates; Organophosphonates; Pre-Exposure Prophylaxis; Prodrugs; Rectum; Sexual and Gender Minorities; Tenofovir

2019
Epithelial Cells and Fibroblasts from the Human Female Reproductive Tract Accumulate and Release TFV and TAF to Sustain Inhibition of HIV Infection of CD4+ T cells.
    Scientific reports, 2019, 02-12, Volume: 9, Issue:1

    Topics: Adenine; Adult; Alanine; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cervix Uteri; Drug Resistance, Multiple; Endometrium; Epithelial Cells; Female; Fibroblasts; Genitalia, Female; HIV Infections; Humans; Middle Aged; Organophosphates; Tenofovir; Vagina

2019
A Comparison of Plasma Efavirenz and Tenofovir, Dried Blood Spot Tenofovir-Diphosphate, and Self-Reported Adherence to Predict Virologic Suppression Among South African Women.
    Journal of acquired immune deficiency syndromes (1999), 2019, 07-01, Volume: 81, Issue:3

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Anti-Retroviral Agents; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Emtricitabine; Female; HIV Infections; Humans; Logistic Models; Organophosphates; Plasma; Self Report; South Africa; Tenofovir

2019
Effective use of pre-exposure prophylaxis (PrEP) Among stimulant users with multiple condomless sex partners: a longitudinal study of men who have sex with men in Los Angeles.
    AIDS care, 2019, Volume: 31, Issue:10

    Topics: Adenine; Adult; Anti-Retroviral Agents; Central Nervous System Stimulants; Condoms; HIV Infections; Homosexuality, Male; Humans; Longitudinal Studies; Los Angeles; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Sexual Partners; Tenofovir; Unsafe Sex

2019
Predictive Value of Tenofovir Diphosphate in Dried Blood Spots for Future Viremia in Persons Living With HIV.
    The Journal of infectious diseases, 2019, 07-19, Volume: 220, Issue:4

    Topics: Adenine; Adult; Anti-HIV Agents; Biomarkers; Female; HIV; HIV Infections; Humans; Male; Medication Adherence; Middle Aged; Organophosphates; Predictive Value of Tests; Tenofovir; Viral Load; Viremia

2019
Brief Report: Short-Term Adherence Marker to PrEP Predicts Future Nonretention in a Large PrEP Demo Project: Implications for Point-of-Care Adherence Testing.
    Journal of acquired immune deficiency syndromes (1999), 2019, 06-01, Volume: 81, Issue:2

    Topics: Adenine; Adult; Anti-HIV Agents; Dried Blood Spot Testing; Emtricitabine; Female; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Organophosphates; Point-of-Care Testing; Pre-Exposure Prophylaxis; Proportional Hazards Models; Prospective Studies; Tenofovir

2019
Depot Medroxyprogesterone Acetate and the Vaginal Microbiome as Modifiers of Tenofovir Diphosphate and Lamivudine Triphosphate Concentrations in the Female Genital Tract of Ugandan Women: Implications for Tenofovir Disoproxil Fumarate/Lamivudine in Preexp
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 04-10, Volume: 70, Issue:8

    Topics: Adenine; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Medroxyprogesterone Acetate; Microbiota; Organophosphates; Pre-Exposure Prophylaxis; Tenofovir; Uganda

2020
Tenofovir Plasma Concentration from Preexposure Prophylaxis at the Time of Potential HIV Exposure: a Population Pharmacokinetic Modeling and Simulation Study Involving Serodiscordant Couples in East Africa.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:8

    Topics: Adenine; Anti-HIV Agents; Bayes Theorem; Cross-Over Studies; Female; HIV; HIV Infections; Humans; Kenya; Leukocytes, Mononuclear; Male; Organophosphates; Pre-Exposure Prophylaxis; Prospective Studies; Sexual Partners; Tenofovir; Uganda

2019
The determination of human peripheral blood mononuclear cell counts using a genomic DNA standard and application in tenofovir diphosphate quantitation.
    Analytical biochemistry, 2019, 11-15, Volume: 585

    Topics: Adenine; Alanine; Cell Count; Chromatography, High Pressure Liquid; DNA; Fluorescent Dyes; Genomics; Humans; Image Cytometry; Intercalating Agents; Leukocytes, Mononuclear; Organophosphates; Prodrugs; Tandem Mass Spectrometry; Tenofovir

2019
Octadecyloxyethyl benzyl tenofovir: A novel tenofovir diester provides sustained intracellular levels of tenofovir diphosphate.
    Antiviral research, 2019, Volume: 171

    Topics: Adenine; Chemistry Techniques, Synthetic; Esters; Humans; Molecular Structure; Organophosphates; Tenofovir; Tissue Distribution

2019
Factors associated with tenofovir diphosphate concentrations in dried blood spots in persons living with HIV.
    The Journal of antimicrobial chemotherapy, 2020, 06-01, Volume: 75, Issue:6

    Topics: Adenine; Adolescent; Anti-HIV Agents; Female; HIV Infections; Humans; Male; Organophosphates; Tenofovir

2020
Immunoassay for HIV Drug Metabolites Tenofovir and Tenofovir Diphosphate.
    ACS infectious diseases, 2020, 07-10, Volume: 6, Issue:7

    Topics: Adenine; Anti-HIV Agents; HIV Infections; Humans; Immunoassay; Medication Adherence; Organophosphates; Pharmaceutical Preparations; Tenofovir

2020
A comparison of covariate selection techniques applied to pre-exposure prophylaxis (PrEP) drug concentration data in men and transgender women at risk for HIV.
    Journal of pharmacokinetics and pharmacodynamics, 2021, Volume: 48, Issue:5

    Topics: Adenine; Adult; Anti-HIV Agents; Female; HIV Infections; Humans; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Tenofovir; Transgender Persons

2021
A 28-Day Toxicity Study of Tenofovir Alafenamide Hemifumarate by Subcutaneous Infusion in Rats and Dogs.
    Microbiology spectrum, 2021, 09-03, Volume: 9, Issue:1

    Topics: Adenine; Alanine; Animals; Anti-HIV Agents; Dogs; Edema; HIV Infections; HIV-1; Infusions, Subcutaneous; Male; Organophosphates; Pre-Exposure Prophylaxis; Rats; Tenofovir

2021
Transformation of tenofovir into stable ProTide nanocrystals with long-acting pharmacokinetic profiles.
    Nature communications, 2021, 09-16, Volume: 12, Issue:1

    Topics: Adenine; Alanine; Animals; Anti-HIV Agents; Drug Stability; Female; HIV Infections; HIV-1; Humans; Male; Nanoparticles; Organophosphates; Prodrugs; Rats, Sprague-Dawley; Tenofovir; Therapeutic Equivalency

2021
Use of Tenofovir Diphosphate Levels to Predict Viremia During the Postpartum Period in Women Living With Human Immunodeficiency Virus (HIV): A Nested Case-Control Study.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 09-14, Volume: 75, Issue:5

    Topics: Adenine; Anti-HIV Agents; Case-Control Studies; Female; HIV; HIV Infections; Humans; Organophosphates; Postpartum Period; Pregnancy; Tenofovir; Viremia

2022
Cumulative tenofovir diphosphate exposure in persons with HIV taking single- vs. multiple-tablet regimens.
    Pharmacotherapy, 2022, Volume: 42, Issue:8

    Topics: Adenine; Anti-HIV Agents; HIV Infections; Humans; Organophosphates; Tablets; Tenofovir

2022
Safety and efficacy of a biodegradable implant releasing tenofovir alafenamide for vaginal protection in a macaque model.
    The Journal of antimicrobial chemotherapy, 2022, 10-28, Volume: 77, Issue:11

    Topics: Absorbable Implants; Alanine; Animals; Anti-HIV Agents; Emtricitabine; Female; HIV; HIV Infections; Macaca; Necrosis; Simian Immunodeficiency Virus; Tenofovir

2022
Effect of alcohol exposure on the efficacy and safety of tenofovir alafenamide fumarate, a major medicine against human immunodeficiency virus.
    Biochemical pharmacology, 2022, Volume: 204

    Topics: Adenine; Alanine; Alcohol Drinking; Anti-HIV Agents; Carboxylic Ester Hydrolases; Chromatography, Liquid; Ethanol; Fumarates; HIV; HIV Infections; Humans; Lipids; Organophosphates; Tandem Mass Spectrometry; Tenofovir

2022
PrEP Use and Adherence among Transgender Persons in Chicago, IL (SHIPP Study, 2014-2018, USA).
    AIDS and behavior, 2023, Volume: 27, Issue:3

    Topics: Anti-HIV Agents; Chicago; Female; HIV Infections; Homosexuality, Male; Humans; Male; Medication Adherence; Pre-Exposure Prophylaxis; Tenofovir; Transgender Persons; United States

2023
Continued attendance in a PrEP program despite low adherence and non-protective drug levels among adolescent girls and young women in Kenya: Results from a prospective cohort study.
    PLoS medicine, 2022, Volume: 19, Issue:9

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Child; Contraceptive Agents; Diphosphates; Emtricitabine; Female; HIV Infections; Humans; Infant; Kenya; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Prospective Studies; Tenofovir; Young Adult

2022
Challenges with PrEP Uptake and Adherence Among Gay, Bisexual, and Other Men Who Have Sex with Men in Kisumu, Kenya.
    AIDS and behavior, 2023, Volume: 27, Issue:4

    Topics: Anti-HIV Agents; HIV Infections; Homosexuality, Male; Humans; Kenya; Male; Medication Adherence; Pre-Exposure Prophylaxis; Sexual and Gender Minorities; Tenofovir

2023
Nucleoside Triphosphate Diphosphohydrolase 1 Exhibits Enzymatic Activity toward Tenofovir Diphosphate.
    Drug metabolism and disposition: the biological fate of chemicals, 2023, Volume: 51, Issue:3

    Topics: Adenosine Triphosphate; Adult; Anti-HIV Agents; Colorectal Neoplasms; Diphosphates; HIV Infections; Humans; Kinetics; Nucleosides; Nucleotides; Tenofovir

2023
Renal Dysfunction due to Tenofovir-Diphosphate Inhibition of Mitochondrial Complex V (ATP Synthase).
    Function (Oxford, England), 2023, Volume: 4, Issue:3

    Topics: Adenosine Triphosphate; Diphosphates; Humans; Kidney Diseases; Tenofovir

2023