Page last updated: 2024-08-24

tenofovir and pyrophosphate

tenofovir has been researched along with pyrophosphate in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's4 (36.36)24.3611
2020's6 (54.55)2.80

Authors

AuthorsStudies
Boojamra, CG; Callebaut, C; Cihlar, T; Gao, Y; Hui, H; Lin, KY; Mackman, RL; Ray, AS; Stray, K; Vela, JE; Zhang, L1
Bronsveld, W; Haverkort, ME; Huitema, AD; Lips, P; Slieker, WA; ter Heine, R; van der Spek, BW1
Anderson, PL; Bushman, LR; Kiser, JJ; Klein, B; Ray, ML; Rower, JE; Zheng, JH1
Adams, JL; Crucitti, T; De Baetselier, I; Fransen, K; Kashuba, AD; Menezes, P; Patterson, KB; Prince, HM; Sykes, C; Van Damme, L1
Anderson, PL; Bushman, LR; Castillo-Mancilla, JR; Chen, X; Kiser, JJ; MaWhinney, S; Seifert, SM; Zheng, JH1
Abuna, F; Anderson, PL; Baeten, JM; Dettinger, JC; John-Stewart, G; Kinuthia, J; Lagat, H; Mugwanya, K; Odinga, D; Pintye, J; Sila, J1
Anderson, PL; Brooks, KM; Bushman, L; Castillo-Mancilla, JR; Ibrahim, M; Kiser, JJ; MaWhinney, S; Morrow, M; Nemkov, C; Peterson, S; Yager, JL1
Brady, M; Chen, YQ; Cover, J; Cressey, TR; Drain, P; Duerr, A; Kariithi, E; Mori, K; Obanda, R; Obong'o, C; Okomo, G; Oluoch-Madiang, D; Tapsoba, JD1
Brache, V; Chandra, N; Clark, MR; Cochon, L; Doncel, GF; Erikson, DW; Fichorova, RN; Hanif, H; Herold, BC; Jacot, T; Ju, S; Marzinke, MA; Ouattara, LA; Parikh, U; Peet, M; Schwartz, JL; Thurman, AR; Tolley, E; Yousefieh, N1
Seneviratne, HK1
Sluis-Cremer, N1

Trials

2 trial(s) available for tenofovir and pyrophosphate

ArticleYear
Tenofovir-diphosphate in peripheral blood mononuclear cells during low, medium and high adherence to emtricitabine/ tenofovir alafenamide vs. emtricitabine/ tenofovir disoproxil fumarate.
    AIDS (London, England), 2021, 12-01, Volume: 35, Issue:15

    Topics: Alanine; Anti-HIV Agents; Diphosphates; Emtricitabine; HIV Infections; Humans; Leukocytes, Mononuclear; Tenofovir

2021
Randomized, placebo controlled phase I trial of the safety, pharmacokinetics, pharmacodynamics and acceptability of a 90 day tenofovir plus levonorgestrel vaginal ring used continuously or cyclically in women: The CONRAD 138 study.
    PloS one, 2022, Volume: 17, Issue:10

    Topics: Anovulation; Antiviral Agents; Contraceptive Agents; Contraceptive Devices, Female; Diphosphates; Female; HIV Core Protein p24; HIV Infections; Humans; Levonorgestrel; Male; Semen; Tenofovir

2022

Other Studies

9 other study(ies) available for tenofovir and pyrophosphate

ArticleYear
Intracellular metabolism of the nucleotide prodrug GS-9131, a potent anti-human immunodeficiency virus agent.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Adenine; Anti-HIV Agents; Diphosphates; Guanosine; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Organophosphonates; Prodrugs; Reverse Transcriptase Inhibitors; Tenofovir

2008
Tenofovir-induced Fanconi syndrome and osteomalacia in two HIV-infected patients: role of intracellular tenofovir diphosphate levels and review of the literature.
    Scandinavian journal of infectious diseases, 2011, Volume: 43, Issue:10

    Topics: Adenine; Adult; Anti-HIV Agents; Diphosphates; Fanconi Syndrome; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Osteomalacia; Radionuclide Imaging; Tenofovir; Whole Body Imaging

2011
Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC-MS/MS detection.
    Journal of pharmaceutical and biomedical analysis, 2011, Sep-10, Volume: 56, Issue:2

    Topics: Adenine; Anion Exchange Resins; Antiviral Agents; Calibration; Chromatography, Liquid; Deoxycytidine; Diphosphates; Emtricitabine; Humans; Lamivudine; Leukocytes, Mononuclear; Nucleosides; Organophosphonates; Phosphates; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Tenofovir; Zidovudine

2011
Tenofovir diphosphate and emtricitabine triphosphate concentrations in blood cells compared with isolated peripheral blood mononuclear cells: a new measure of antiretroviral adherence?
    Journal of acquired immune deficiency syndromes (1999), 2013, Mar-01, Volume: 62, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Blood Cells; Deoxycytidine; Diphosphates; Emtricitabine; Female; HIV Infections; Humans; Leukocytes, Mononuclear; Male; Medication Adherence; Middle Aged; Organophosphonates; Polyphosphates; Tenofovir

2013
Model Linking Plasma and Intracellular Tenofovir/Emtricitabine with Deoxynucleoside Triphosphates.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Adult; Anti-HIV Agents; Computer Simulation; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Diphosphates; Emtricitabine; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Models, Biological; Polyphosphates; Prospective Studies; Tenofovir; Young Adult

2016
Frequency and Predictors of Tenofovir-diphosphate Detection Among Young Kenyan Women in a Real-world Pre-exposure Prophylaxis Implementation Program.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 12-03, Volume: 71, Issue:9

    Topics: Anti-HIV Agents; Diphosphates; Emtricitabine; Female; HIV Infections; Humans; Kenya; Medication Adherence; Pre-Exposure Prophylaxis; Pregnancy; Tenofovir

2020
Continued attendance in a PrEP program despite low adherence and non-protective drug levels among adolescent girls and young women in Kenya: Results from a prospective cohort study.
    PLoS medicine, 2022, Volume: 19, Issue:9

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Child; Contraceptive Agents; Diphosphates; Emtricitabine; Female; HIV Infections; Humans; Infant; Kenya; Male; Medication Adherence; Organophosphates; Pre-Exposure Prophylaxis; Prospective Studies; Tenofovir; Young Adult

2022
Nucleoside Triphosphate Diphosphohydrolase 1 Exhibits Enzymatic Activity toward Tenofovir Diphosphate.
    Drug metabolism and disposition: the biological fate of chemicals, 2023, Volume: 51, Issue:3

    Topics: Adenosine Triphosphate; Adult; Anti-HIV Agents; Colorectal Neoplasms; Diphosphates; HIV Infections; Humans; Kinetics; Nucleosides; Nucleotides; Tenofovir

2023
Renal Dysfunction due to Tenofovir-Diphosphate Inhibition of Mitochondrial Complex V (ATP Synthase).
    Function (Oxford, England), 2023, Volume: 4, Issue:3

    Topics: Adenosine Triphosphate; Diphosphates; Humans; Kidney Diseases; Tenofovir

2023