tenofovir and gs-9148
tenofovir has been researched along with gs-9148 in 7 studies
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Boojamra, CG; Cihlar, T; Douglas, J; Grant, D; Hui, H; Lin, KY; Mackman, RL; Petrakovsky, O; Prasad, V; Ray, AS | 1 |
| Boojamra, CG; Cihlar, T; Douglas, J; Grant, D; Kim, CU; Mackman, RL; Markevitch, DY; Prasad, V; Ray, AS | 1 |
| Carey, AC; Cihlar, T; Fisher, R; Laflamme, G; Mackman, R; Ray, AS; Vela, JE | 1 |
| Barron, AC; Boojamra, CG; Chen, JM; Cihlar, T; Desai, MC; Gao, Y; Kim, CU; Laflamme, G; Lee, SK; Mackman, RL; Markevitch, DY; Parrish, JP; Petrakovsky, OV; Ray, AS; Sparacino, ML; Sperandio, D; Vela, JE | 1 |
| Birkus, G; Boojamra, CG; Cihlar, T; Desai, MC; Douglas, JL; Gao, Y; Grant, D; Hui, HC; Laflamme, G; Lin, KY; Mackman, RL; Markevitch, DY; McDermott, M; Mishra, R; Pakdaman, R; Petrakovsky, OV; Ray, AS; Vela, JE; Zhang, L | 1 |
| Boojamra, CG; Callebaut, C; Cihlar, T; Gao, Y; Hui, H; Lin, KY; Mackman, RL; Ray, AS; Stray, K; Vela, JE; Zhang, L | 1 |
| De Clercq, E | 1 |
Reviews
1 review(s) available for tenofovir and gs-9148
| Article | Year |
|---|---|
The clinical potential of the acyclic (and cyclic) nucleoside phosphonates: the magic of the phosphonate bond.
Topics: Adenine; Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Guanosine; Hepatitis B; HIV Infections; Humans; Organophosphonates; Prodrugs; Structure-Activity Relationship; Tenofovir | 2011 |
Other Studies
6 other study(ies) available for tenofovir and gs-9148
| Article | Year |
|---|---|
Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.
Topics: Anti-HIV Agents; Fluorine; Guanosine; Humans; Molecular Structure; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine | 2008 |
Synthesis and anti-HIV activity of GS-9148 (2'-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor.
Topics: Anti-HIV Agents; DNA, Mitochondrial; Fluorine; Guanosine; HIV Reverse Transcriptase; Humans; Molecular Structure; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine | 2008 |
Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulation.
Topics: Adenine; Animals; Cell Line; Cell Survival; CHO Cells; Cidofovir; Cricetinae; Cricetulus; Cytosine; Guanosine; HIV Reverse Transcriptase; Humans; In Vitro Techniques; Kidney; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir | 2009 |
Design, synthesis, and anti-HIV activity of 4'-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Cell Line, Tumor; Drug Design; HIV Reverse Transcriptase; Humans; Models, Molecular; Molecular Structure; Nucleosides; Organophosphonates; Prodrugs; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2009 |
Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148.
Topics: Adenine; Animals; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Dogs; Drug Design; Drug Resistance, Viral; Drug Stability; Guanosine; HIV-1; Nucleosides; Organophosphonates; Prodrugs; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured | 2010 |
Intracellular metabolism of the nucleotide prodrug GS-9131, a potent anti-human immunodeficiency virus agent.
Topics: Adenine; Anti-HIV Agents; Diphosphates; Guanosine; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Organophosphonates; Prodrugs; Reverse Transcriptase Inhibitors; Tenofovir | 2008 |