Page last updated: 2024-08-24

tenofovir and gs-9148

tenofovir has been researched along with gs-9148 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boojamra, CG; Cihlar, T; Douglas, J; Grant, D; Hui, H; Lin, KY; Mackman, RL; Petrakovsky, O; Prasad, V; Ray, AS1
Boojamra, CG; Cihlar, T; Douglas, J; Grant, D; Kim, CU; Mackman, RL; Markevitch, DY; Prasad, V; Ray, AS1
Carey, AC; Cihlar, T; Fisher, R; Laflamme, G; Mackman, R; Ray, AS; Vela, JE1
Barron, AC; Boojamra, CG; Chen, JM; Cihlar, T; Desai, MC; Gao, Y; Kim, CU; Laflamme, G; Lee, SK; Mackman, RL; Markevitch, DY; Parrish, JP; Petrakovsky, OV; Ray, AS; Sparacino, ML; Sperandio, D; Vela, JE1
Birkus, G; Boojamra, CG; Cihlar, T; Desai, MC; Douglas, JL; Gao, Y; Grant, D; Hui, HC; Laflamme, G; Lin, KY; Mackman, RL; Markevitch, DY; McDermott, M; Mishra, R; Pakdaman, R; Petrakovsky, OV; Ray, AS; Vela, JE; Zhang, L1
Boojamra, CG; Callebaut, C; Cihlar, T; Gao, Y; Hui, H; Lin, KY; Mackman, RL; Ray, AS; Stray, K; Vela, JE; Zhang, L1
De Clercq, E1

Reviews

1 review(s) available for tenofovir and gs-9148

ArticleYear
The clinical potential of the acyclic (and cyclic) nucleoside phosphonates: the magic of the phosphonate bond.
    Biochemical pharmacology, 2011, Jul-15, Volume: 82, Issue:2

    Topics: Adenine; Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Guanosine; Hepatitis B; HIV Infections; Humans; Organophosphonates; Prodrugs; Structure-Activity Relationship; Tenofovir

2011

Other Studies

6 other study(ies) available for tenofovir and gs-9148

ArticleYear
Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148.
    Bioorganic & medicinal chemistry letters, 2008, Feb-01, Volume: 18, Issue:3

    Topics: Anti-HIV Agents; Fluorine; Guanosine; Humans; Molecular Structure; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine

2008
Synthesis and anti-HIV activity of GS-9148 (2'-Fd4AP), a novel nucleoside phosphonate HIV reverse transcriptase inhibitor.
    Bioorganic & medicinal chemistry letters, 2008, Feb-01, Volume: 18, Issue:3

    Topics: Anti-HIV Agents; DNA, Mitochondrial; Fluorine; Guanosine; HIV Reverse Transcriptase; Humans; Molecular Structure; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine

2008
Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulation.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Adenine; Animals; Cell Line; Cell Survival; CHO Cells; Cidofovir; Cricetinae; Cricetulus; Cytosine; Guanosine; HIV Reverse Transcriptase; Humans; In Vitro Techniques; Kidney; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir

2009
Design, synthesis, and anti-HIV activity of 4'-modified carbocyclic nucleoside phosphonate reverse transcriptase inhibitors.
    Bioorganic & medicinal chemistry, 2009, Feb-15, Volume: 17, Issue:4

    Topics: Anti-HIV Agents; Cell Line, Tumor; Drug Design; HIV Reverse Transcriptase; Humans; Models, Molecular; Molecular Structure; Nucleosides; Organophosphonates; Prodrugs; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2009
Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148.
    Bioorganic & medicinal chemistry, 2010, May-15, Volume: 18, Issue:10

    Topics: Adenine; Animals; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Dogs; Drug Design; Drug Resistance, Viral; Drug Stability; Guanosine; HIV-1; Nucleosides; Organophosphonates; Prodrugs; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured

2010
Intracellular metabolism of the nucleotide prodrug GS-9131, a potent anti-human immunodeficiency virus agent.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Adenine; Anti-HIV Agents; Diphosphates; Guanosine; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Organophosphonates; Prodrugs; Reverse Transcriptase Inhibitors; Tenofovir

2008