tenofovir has been researched along with gs-9131 in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Birkus, G; Cihlar, T; Gibbs, C; Kutty, N; Lee, W; Liu, X; MacArthur, H; McDermott, M; Swaminathan, S; Wang, R | 1 |
| Boojamra, CG; Callebaut, C; Cihlar, T; Gao, Y; Hui, H; Lin, KY; Mackman, RL; Ray, AS; Stray, K; Vela, JE; Zhang, L | 1 |
| Carey, AC; Cihlar, T; Fisher, R; Laflamme, G; Mackman, R; Ray, AS; Vela, JE | 1 |
| De Clercq, E | 1 |
1 review(s) available for tenofovir and gs-9131
| Article | Year |
|---|---|
The clinical potential of the acyclic (and cyclic) nucleoside phosphonates: the magic of the phosphonate bond.
Topics: Adenine; Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Guanosine; Hepatitis B; HIV Infections; Humans; Organophosphonates; Prodrugs; Structure-Activity Relationship; Tenofovir | 2011 |
3 other study(ies) available for tenofovir and gs-9131
| Article | Year |
|---|---|
Cathepsin A is the major hydrolase catalyzing the intracellular hydrolysis of the antiretroviral nucleotide phosphonoamidate prodrugs GS-7340 and GS-9131.
Topics: Adenine; Alanine; Anti-Retroviral Agents; Catalysis; Cathepsin A; Cell Size; Cells, Cultured; Enzyme Activation; Fibroblasts; Humans; Hydrolysis; Kinetics; Monocytes; Prodrugs; Recombinant Proteins; Substrate Specificity; Tenofovir | 2007 |
Intracellular metabolism of the nucleotide prodrug GS-9131, a potent anti-human immunodeficiency virus agent.
Topics: Adenine; Anti-HIV Agents; Diphosphates; Guanosine; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Lymphocyte Activation; Organophosphonates; Prodrugs; Reverse Transcriptase Inhibitors; Tenofovir | 2008 |
Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulation.
Topics: Adenine; Animals; Cell Line; Cell Survival; CHO Cells; Cidofovir; Cricetinae; Cricetulus; Cytosine; Guanosine; HIV Reverse Transcriptase; Humans; In Vitro Techniques; Kidney; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir | 2009 |