Compounds > tenofovir
Page last updated: 2024-08-24

tenofovir and ganciclovir

tenofovir has been researched along with ganciclovir in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's6 (42.86)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Alvarez, K; Balzarini, J; Barral, K; Canard, B; Neyts, J; Priet, S; Sire, J1
Lombardo, F; Obach, RS; Waters, NJ1
Chou, KC; González-Díaz, H; Martinez de la Vega, O; Prado-Prado, FJ; Ubeira, FM; Uriarte, E1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Agrofoglio, LA; Alexandre, JA; Andrei, G; Azzouzi, A; Balzarini, J; Broggi, J; Caillat, C; Deville-Bonne, D; El-Amri, C; Eriksson, S; Lin, J; Meyer, P; Pradère, U; Roy, V; Snoeck, R; Topalis, D1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Andrei, G; Buckheit, RW; De Jonghe, S; Groaz, E; Hartman, T; Herdewijn, P; Kalkeri, R; Luo, M; Ptak, RG; Schols, D; Snoeck, R1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Vere Hodge, A1
Fridland, A; Olson, L; Ray, AS1
Feng, B; Litchfield, J; Mathialagan, S; Piotrowski, MA; Tess, DA; Varma, MV1
To, EE1

Reviews

2 review(s) available for tenofovir and ganciclovir

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Cell and Tissue Specific Metabolism of Nucleoside and Nucleotide Drugs: Case Studies and Implications for Precision Medicine.
    Drug metabolism and disposition: the biological fate of chemicals, 2023, Volume: 51, Issue:3

    Topics: Acyclovir; Antiviral Agents; Ganciclovir; HIV Infections; Humans; Nucleosides; Nucleotides; Precision Medicine; Tenofovir

2023

Other Studies

12 other study(ies) available for tenofovir and ganciclovir

ArticleYear
Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine.
    Journal of medicinal chemistry, 2006, Dec-28, Volume: 49, Issue:26

    Topics: Adenine; Animals; Anti-HIV Agents; Antiviral Agents; Boranes; Boron Compounds; Chlorocebus aethiops; DNA Viruses; HIV-1; Humans; In Vitro Techniques; Nucleosides; Organophosphonates; Phosphates; RNA Viruses; Structure-Activity Relationship; Vero Cells; Virus Replication

2006
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks.
    Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2

    Topics: Anti-Infective Agents; Antiviral Agents; Artificial Intelligence; Computer Simulation; Drug Evaluation, Preclinical; Molecular Structure; Quantitative Structure-Activity Relationship

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates.
    Journal of medicinal chemistry, 2011, Jan-13, Volume: 54, Issue:1

    Topics: Antiviral Agents; Catalytic Domain; Cells, Cultured; Crystallography, X-Ray; Herpesviridae; Humans; Ligands; Models, Molecular; Molecular Structure; Nucleoside-Phosphate Kinase; Organophosphonates; Prodrugs; Pyrimidine Nucleosides; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Kinase

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs.
    Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Aspartic Acid; Cell Line; Cytomegalovirus; Drug Resistance, Viral; Drug Stability; Esters; Hepatitis B virus; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Microsomes, Liver; Nucleosides; Organophosphonates; Prodrugs; Stereoisomerism; Structure-Activity Relationship

2017
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Antiviral Research--16th Annual International Conference. Satellite symposium: clinical update on antiviral drugs. 27 April-1 May 2003, Savannah, GA, USA.
    IDrugs : the investigational drugs journal, 2003, Volume: 6, Issue:6

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Clinical Trials as Topic; Enfuvirtide; Ganciclovir; Hepatitis B; HIV Envelope Protein gp41; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Peptide Fragments; Tenofovir; Valganciclovir

2003
Role of purine nucleoside phosphorylase in interactions between 2',3'-dideoxyinosine and allopurinol, ganciclovir, or tenofovir.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:4

    Topics: Adenine; Allopurinol; Anti-HIV Agents; Antimetabolites; Antiviral Agents; Biotransformation; Caco-2 Cells; Chromatography, High Pressure Liquid; Didanosine; Drug Interactions; Enzyme Inhibitors; Ganciclovir; Humans; Intestinal Absorption; Kinetics; Organophosphonates; Organophosphorus Compounds; Permeability; Purine-Nucleoside Phosphorylase; Substrate Specificity; Tenofovir

2004
Quantitative Prediction of Human Renal Clearance and Drug-Drug Interactions of Organic Anion Transporter Substrates Using In Vitro Transport Data: A Relative Activity Factor Approach.
    Drug metabolism and disposition: the biological fate of chemicals, 2017, Volume: 45, Issue:4

    Topics: Acyclovir; Anti-Bacterial Agents; Antiviral Agents; Drug Interactions; Ganciclovir; HEK293 Cells; Humans; Kidney; Models, Biological; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Oseltamivir; Penicillin G; Probenecid; Renal Elimination; Tenofovir; Transfection

2017