Page last updated: 2024-08-24

tenofovir and dapivirine

tenofovir has been researched along with dapivirine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.70)29.6817
2010's18 (66.67)24.3611
2020's8 (29.63)2.80

Authors

AuthorsStudies
Anton, P; Cranage, M; Herrera, C; McGowan, I; Shattock, RJ1
Ariën, KK; Bizzarri, BM; Botta, M; Brai, A; Canducci, F; Cascone, L; Casian, A; Ceresola, E; Crespan, E; Dasso Lang, MC; Deodato, D; Dreassi, E; Greco, AM; Maga, G; Tintori, C; Vanham, G; Zamperini, C1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Albright, TH; Fabian, J; Gupta, KM; Johnson, TJ; Kiser, PF1
Kaptur, PE; Mertenskoetter, T1
Colby-Germinario, SP; Schachter, JR; Schader, SM; Wainberg, MA; Xu, H1
Colby-Germinario, SP; Ibanescu, RI; Moisi, D; Oliveira, M; Schader, SM; Wainberg, MA1
Moncla, BJ; Pryke, K; Rohan, LC; Yang, H1
Szpir, M; Van Damme, L1
McGowan, I1
Akil, A; Cost, M; Devlin, B; Rohan, LC1
Agashe, H; Akil, A; Devlin, B; Dezzutti, CS; Hillier, SL; Moncla, BJ; Rohan, LC; Shi, Y; Uranker, K1
Cameron, D; Dias, N; Dreier, P; Holding, J; Holt, JD; Muntendam, A; Nuttall, J; Oostebring, F; Rohan, L1
Cuppone, AM; De Falco, G; Ekeruche-Makinde, J; Hijazi, K; Hold, GL; Iannelli, F; Kelly, CG; Pozzi, G; Shattock, R; Smith, K; Stincarelli, MA1
Berry, S; Ekeruche-Makinde, J; El-Omar, EM; Frank, B; Gwozdz, G; Hijazi, K; Hold, GL; Iannelli, F; Kelly, C; Mukhopadhya, I; Murray, GI; Pozzi, G; Shattock, R; Thomson, J1
Blakney, AK; Jiang, Y; Little, AB; Woodrow, KA1
Abdool Karim, SS; Baxter, C; Passmore, JS1
Cameron, SA; Cheshenko, N; Frank, B; Fredricks, D; Herold, BC; Keller, MJ; Mesquita, PM; Reagle, K; Sinclair, S; Srinivasan, S; Taneva, E; Weinrick, B1
Avenant, C; Bick, AJ; Dlamini, S; Enfield, K; Hapgood, JP; Kuipa, M; Maritz, MF; Moliki, JM; Skosana, S; van der Spuy, Z; Woodland, JG1
Avenant, C; Dlamini, S; Enfield, K; Hapgood, JP; Kuipa, M1
Bekker, LG; Carter, A; Craig, C; Devlin, B; Gill, K; Gwetu, T; Kotze, P; Kusemererwa, S; Louw, C; Mabude, Z; Malherbe, M; Mans, W; Moraba, R; Nel, A; Rosenberg, Z; Steytler, J; Tempelman, H; Van Baelen, B; van der Ryst, E; van Niekerk, N1
Baeten, JM; Balán, IC; Brown, ER; Bunge, K; Chinula, L; Chirenje, ZM; Garcia, M; Gati Mirembe, B; Govender, V; Hendrix, CW; Hillier, SL; Hunidzarira, P; Jacobson, C; Jiao, Y; Jones, J; Livant, E; Makanani, B; Mansoor, LE; Mayo, AJ; Mellors, JW; Mgodi, NM; Mhlanga, F; Naidoo, L; Nair, G; Nakabiito, C; Nel, A; Ngure, K; Palanee-Phillips, T; Parikh, UM; Patterson, K; Peda, M; Ramjee, G; Rosenberg, Z; Scheckter, R; Singh, D; Singh, N; Siva, S; Soto-Torres, LE; Szydlo, DW; Taha, TE; Torjesen, K; van der Straten, A1
Fried, JR; Fuqua, JL; Minooei, F; Palmer, KE; Steinbach-Rankins, JM1
Mwethera, PG; Obiero, J; Ogongo, P; Wiysonge, CS1
Akello, CA; Anderson, P; Baeten, JM; Bekker, LG; Brown, ER; Bunge, K; Celum, C; Garcia, M; Hendrix, C; Hillier, SL; Hosek, S; Jacobson, C; Johnson, S; Levy, L; Livant, E; Macdonald, P; McClure, T; Milan, G; Muhlanga, F; Nair, G; Nakabiito, C; Nakalega, R; Ngure, K; Palanee-Phillips, T; Parikh, U; Reddy, K; Rooney, JF; Siziba, B; Soto-Torres, L; Steytler, J; Szydlo, D; Tahuringana, E; van der Straten, A1
Balkus, JE; Bunge, K; Chakhtoura, N; Chappell, CA; Fairlie, L; Gadama, L; Hillier, SL; Matrimbira, M; Mayo, AJ; Mgodi, N; Nakabiito, C; Piper, J; Richardson, B; Szydlo, DW1

Reviews

5 review(s) available for tenofovir and dapivirine

ArticleYear
Update on microbicide research and development - seeking new HIV prevention tools for women.
    European journal of medical research, 2011, Jan-27, Volume: 16, Issue:1

    Topics: Adenine; Administration, Intravaginal; Adult; Africa South of the Sahara; Anti-HIV Agents; Anti-Infective Agents; Clinical Trials as Topic; Cyclohexanes; Drug Discovery; Female; HIV Infections; Humans; Male; Maraviroc; Organophosphonates; Pyridines; Pyrimidines; Tenofovir; Triazoles; Urea

2011
Current status of topical antiretroviral chemoprophylaxis.
    Current opinion in HIV and AIDS, 2012, Volume: 7, Issue:6

    Topics: Adenine; Administration, Intravaginal; Administration, Topical; Anilides; Anti-HIV Agents; Chemoprevention; Clinical Trials, Phase II as Topic; Female; Furans; HIV Infections; Humans; Organophosphonates; Pyrimidines; Tenofovir; Thioamides; Treatment Outcome

2012
An overview of antiretroviral pre-exposure prophylaxis of HIV infection.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2014, Volume: 71, Issue:6

    Topics: Adenine; Anti-HIV Agents; Cyclohexanes; Drug Resistance, Viral; Female; HIV Infections; Humans; Male; Maraviroc; Medication Adherence; Nitriles; Organophosphonates; Pre-Exposure Prophylaxis; Pyridones; Pyrimidines; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Triazoles

2014
The microbiome and HIV prevention strategies in women.
    Current opinion in HIV and AIDS, 2018, Volume: 13, Issue:1

    Topics: Anti-Retroviral Agents; Female; Gardnerella vaginalis; HIV Infections; Humans; Microbiota; Pre-Exposure Prophylaxis; Pyrimidines; Tenofovir; Treatment Failure; Vagina; Vaginosis, Bacterial

2018
Topical microbicides for preventing sexually transmitted infections.
    The Cochrane database of systematic reviews, 2021, 03-13, Volume: 3

    Topics: Acrylic Resins; Adenine; Administration, Intravaginal; Agaricales; Anti-HIV Agents; Anti-Infective Agents, Local; Bias; Cellulose; Female; HIV Infections; Humans; Naphthalenesulfonates; Placebos; Polymers; Pyrimidines; Seaweed; Sexually Transmitted Diseases; Tenofovir

2021

Trials

4 trial(s) available for tenofovir and dapivirine

ArticleYear
Safety, adherence, and HIV-1 seroconversion among women using the dapivirine vaginal ring (DREAM): an open-label, extension study.
    The lancet. HIV, 2021, Volume: 8, Issue:2

    Topics: Administration, Intravaginal; Adolescent; Adult; Anti-HIV Agents; Contraceptive Devices, Female; Female; HIV Infections; HIV-1; Humans; Middle Aged; Patient Compliance; Patient Safety; Pyrimidines; Seroconversion; South Africa; Tenofovir; Treatment Outcome; Uganda

2021
Safety, uptake, and use of a dapivirine vaginal ring for HIV-1 prevention in African women (HOPE): an open-label, extension study.
    The lancet. HIV, 2021, Volume: 8, Issue:2

    Topics: Administration, Intravaginal; Adult; Anti-HIV Agents; Contraceptive Devices, Female; Female; HIV Infections; HIV-1; Humans; Malawi; Patient Compliance; Patient Safety; Pyrimidines; Seroconversion; South Africa; Tenofovir; Treatment Outcome; Uganda; Zimbabwe

2021
Adherence, safety, and choice of the monthly dapivirine vaginal ring or oral emtricitabine plus tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis among African adolescent girls and young women: a randomised, open-label, crossover trial.
    The lancet. HIV, 2023, Volume: 10, Issue:12

    Topics: Adolescent; Anti-HIV Agents; Cross-Over Studies; Emtricitabine; Female; HIV Infections; Humans; Pre-Exposure Prophylaxis; Reverse Transcriptase Inhibitors; South Africa; Tenofovir

2023
DELIVER: A Safety Study of a Dapivirine Vaginal Ring and Oral PrEP for the Prevention of HIV During Pregnancy.
    Journal of acquired immune deficiency syndromes (1999), 2024, Jan-01, Volume: 95, Issue:1

    Topics: Emtricitabine; Female; Gestational Age; HIV Infections; Humans; Malawi; Pregnancy; Tenofovir

2024

Other Studies

18 other study(ies) available for tenofovir and dapivirine

ArticleYear
Reverse transcriptase inhibitors as potential colorectal microbicides.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Adenine; Anilides; Anti-HIV Agents; Anti-Infective Agents, Local; Colon; Drug Resistance, Viral; Furans; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Organophosphonates; Pyrimidines; Rectum; Reverse Transcriptase Inhibitors; Tenofovir; Thioamides; Tissue Culture Techniques; Virus Replication

2009
Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family.
    Journal of medicinal chemistry, 2016, Mar-24, Volume: 59, Issue:6

    Topics: Administration, Intravaginal; Anti-HIV Agents; Cell Survival; Chemistry, Pharmaceutical; DNA, Viral; Dose-Response Relationship, Drug; Drug Design; Gels; HIV-1; Models, Molecular; Molecular Docking Simulation; Pyrimidines; Reverse Transcriptase Inhibitors

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Segmented polyurethane intravaginal rings for the sustained combined delivery of antiretroviral agents dapivirine and tenofovir.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2010, Feb-19, Volume: 39, Issue:4

    Topics: Adenine; Administration, Intravaginal; Anti-HIV Agents; Anti-Retroviral Agents; Compressive Strength; Delayed-Action Preparations; Drug Combinations; Drug Delivery Systems; Organophosphonates; Polyurethanes; Pyrimidines; Tenofovir

2010
Synergy against drug-resistant HIV-1 with the microbicide antiretrovirals, dapivirine and tenofovir, in combination.
    AIDS (London, England), 2011, Aug-24, Volume: 25, Issue:13

    Topics: Adenine; Drug Resistance, Viral; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Pyrimidines; Reverse Transcriptase Inhibitors; Tenofovir

2011
In vitro resistance profile of the candidate HIV-1 microbicide drug dapivirine.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2

    Topics: Adenine; Anti-HIV Agents; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Pyrimidines; Reverse Transcriptase Inhibitors; Tenofovir

2012
Testing of viscous anti-HIV microbicides using Lactobacillus.
    Journal of microbiological methods, 2012, Volume: 88, Issue:2

    Topics: Adenine; Anilides; Animals; Anti-HIV Agents; Anti-Infective Agents, Local; Cattle; Chemokine CCL5; Colony Count, Microbial; Excipients; Female; Furans; Humans; Lactobacillus; Microbial Sensitivity Tests; Microbial Viability; Organophosphonates; Pyrimidines; Serum Albumin, Bovine; Tenofovir; Thioamides; Vagina; Viscosity

2012
Increased Dapivirine tissue accumulation through vaginal film codelivery of dapivirine and Tenofovir.
    Molecular pharmaceutics, 2014, May-05, Volume: 11, Issue:5

    Topics: Adenine; Administration, Intravaginal; Anti-HIV Agents; Anti-Infective Agents; Drug Delivery Systems; Female; HIV Infections; Humans; In Vitro Techniques; Membranes, Artificial; Organophosphonates; Pyrimidines; Tenofovir; Vagina

2014
Formulation and characterization of polymeric films containing combinations of antiretrovirals (ARVs) for HIV prevention.
    Pharmaceutical research, 2015, Volume: 32, Issue:2

    Topics: Adenine; Administration, Intravaginal; Administration, Topical; Anti-HIV Agents; Chemistry, Pharmaceutical; Drug Carriers; Drug Combinations; Drug Delivery Systems; Female; HIV Infections; HIV-1; Humans; Organophosphonates; Polymers; Pyrimidines; Tenofovir; Vagina

2015
The sheep as a model of preclinical safety and pharmacokinetic evaluations of candidate microbicides.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:7

    Topics: Administration, Intravaginal; Animals; Anti-HIV Agents; Contraceptive Devices, Female; Disease Models, Animal; Drug Carriers; Female; HIV Infections; Pyrimidines; Sheep; Tenofovir; Vagina; Vaginal Creams, Foams, and Jellies

2015
Expression of Genes for Drug Transporters in the Human Female Genital Tract and Modulatory Effect of Antiretroviral Drugs.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Adult; Anti-HIV Agents; Biological Transport; Cell Line; Cell Line, Tumor; Cervix Uteri; Darunavir; Drug Resistance; Drug Synergism; Female; Gene Expression Regulation; Humans; Membrane Transport Proteins; Middle Aged; Organ Culture Techniques; Pyrimidines; Tenofovir; Vagina

2015
Antiretroviral gels: facing the FACTS.
    The lancet. HIV, 2015, Volume: 2, Issue:4

    Topics: Adult; Africa South of the Sahara; Anti-HIV Agents; Anti-Infective Agents, Local; Clinical Trials as Topic; Drug Delivery Systems; Female; Gels; HIV Infections; Humans; Medication Adherence; Pyrimidines; Sexual Behavior; Tenofovir; Women's Health

2015
Drug transporter gene expression in human colorectal tissue and cell lines: modulation with antiretrovirals for microbicide optimization.
    The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:2

    Topics: Aged; Anti-Infective Agents; Caco-2 Cells; Darunavir; Epithelial Cells; Female; Gene Expression; Gene Expression Profiling; Humans; Intestinal Mucosa; Male; Membrane Transport Proteins; Middle Aged; Pyrimidines; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tenofovir

2016
In vitro-ex vivo correlations between a cell-laden hydrogel and mucosal tissue for screening composite delivery systems.
    Drug delivery, 2016, Volume: 24, Issue:1

    Topics: Animals; Chemistry, Pharmaceutical; Cyclohexanes; Delayed-Action Preparations; Drug Delivery Systems; Female; Hydrogel, Polyethylene Glycol Dimethacrylate; Lactic Acid; Macaca nemestrina; Maraviroc; Methacrylates; Mucous Membrane; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Primates; Pyrimidines; Tenofovir; Triazoles; Vagina

2016
Vaginal microbiome modulates topical antiretroviral drug pharmacokinetics.
    JCI insight, 2018, 07-12, Volume: 3, Issue:13

    Topics: Actinobacteria; Adenine; Alanine; Anti-Retroviral Agents; Bacteria; Endocytosis; Female; Gardnerella vaginalis; HIV Infections; Humans; Hydrogen-Ion Concentration; Jurkat Cells; Lactobacillus crispatus; Microbiota; Pyrimidines; Tenofovir; Vagina

2018
Reciprocal Modulation of Antiretroviral Drug and Steroid Receptor Function
    Antimicrobial agents and chemotherapy, 2019, 12-20, Volume: 64, Issue:1

    Topics: Anti-Retroviral Agents; Cell Line, Tumor; Cell Survival; Humans; Inflammation; Peripheral Blood Stem Cells; Progestins; Pyrimidines; Receptors, Glucocorticoid; Receptors, Progesterone; Receptors, Steroid; Tenofovir; Transcription Factors

2019
Maraviroc, tenofovir disoproxil fumarate and dapivirine, activate progesterone receptor B in the absence of progestogens.
    Biochemical and biophysical research communications, 2020, 12-17, Volume: 533, Issue:4

    Topics: Anti-HIV Agents; Binding, Competitive; Cell Line; Contraceptive Agents, Hormonal; HIV Infections; HIV-1; Humans; Immunologic Factors; In Vitro Techniques; Levonorgestrel; Maraviroc; Phosphorylation; Progesterone Congeners; Pyrimidines; Receptors, Progesterone; Tenofovir; Transcriptional Activation

2020
In vitro Study on Synergistic Interactions Between Free and Encapsulated Q-Griffithsin and Antiretrovirals Against HIV-1 Infection.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Anti-HIV Agents; Anti-Retroviral Agents; Cell Death; Cell Line; Drug Compounding; Drug Liberation; Drug Synergism; Female; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Lectins; Nanoparticles; Particle Size; Plant Lectins; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrimidines; Raltegravir Potassium; Recombinant Proteins; Tenofovir

2021