Page last updated: 2024-08-24

tenofovir and cytosine

tenofovir has been researched along with cytosine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (65.00)29.6817
2010's7 (35.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Murono, S; Pagano, JS; Raab-Traub, N1
Hitchcock, MJ; Holý, A; Keith, KA; Kern, ER; Lee, WA1
De Clercq, E6
Bleasby, K; Hall, LA; Mohrenweiser, HW; Perry, JL; Pritchard, JB1
Liu, K; Xie, L1
Ida, H; Inui, K; Katsura, T; Tsuji, Y; Uwai, Y1
Alvarez, K; Barral, K; Bussetta, C; Canard, B; Deval, J; Frangeul, A1
Carey, AC; Cihlar, T; Fisher, R; Laflamme, G; Mackman, R; Ray, AS; Vela, JE1
Balzarini, J; De Clercq, E; Koszytkowska-Stawińska, M1
Holý, A; Kasicka, V; Sázelová, P; Solínová, V1
Hostetler, KY; Ray, AS1
Vere Hodge, A1
Leach, KL; Piotrowski, M; Wang, R; Zhang, H; Zhang, X1
Kaltashov, IA; Xu, S1
Calvez, V; Dabis, F; Danaviah, S; de Oliveira, T; Derache, A; Giandhari, J; Gupta, RK; Iwuji, CC; Marcelin, AG; Pillay, D1

Reviews

7 review(s) available for tenofovir and cytosine

ArticleYear
Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections.
    Clinical microbiology reviews, 2003, Volume: 16, Issue:4

    Topics: Adenine; Animals; Cidofovir; Cytosine; DNA Virus Infections; DNA Viruses; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae; Retroviridae Infections; Reverse Transcriptase Inhibitors; Tenofovir

2003
Potential of acyclic nucleoside phosphonates in the treatment of DNA virus and retrovirus infections.
    Expert review of anti-infective therapy, 2003, Volume: 1, Issue:1

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; DNA Virus Infections; Drug Resistance, Viral; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae Infections; Tenofovir

2003
[Advances in the study of nucleoside antiviral drugs].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:8

    Topics: Adenine; Animals; Anti-HIV Agents; Antiviral Agents; Arabinofuranosyluracil; Cidofovir; Cytosine; Dioxolanes; Humans; Molecular Structure; Nucleosides; Organophosphonates; Purine Nucleosides; Tenofovir

2006
The discovery of antiviral agents: ten different compounds, ten different stories.
    Medicinal research reviews, 2008, Volume: 28, Issue:6

    Topics: Acyclovir; Adenine; Antiviral Agents; Benzodiazepines; Benzylamines; Cidofovir; Cyclams; Cytosine; Heterocyclic Compounds; Humans; Imidazoles; Nucleosides; Organophosphonates; Tenofovir; Valacyclovir; Valine; Virus Diseases

2008
The clinical potential of the acyclic (and cyclic) nucleoside phosphonates: the magic of the phosphonate bond.
    Biochemical pharmacology, 2011, Jul-15, Volume: 82, Issue:2

    Topics: Adenine; Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Guanosine; Hepatitis B; HIV Infections; Humans; Organophosphonates; Prodrugs; Structure-Activity Relationship; Tenofovir

2011
Application of kinase bypass strategies to nucleoside antivirals.
    Antiviral research, 2011, Volume: 92, Issue:2

    Topics: Adenine; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytosine; History, 20th Century; History, 21st Century; Humans; Nucleosides; Nucleotides; Organophosphonates; Phosphotransferases; Tenofovir

2011
The Holý Trinity: the acyclic nucleoside phosphonates.
    Advances in pharmacology (San Diego, Calif.), 2013, Volume: 67

    Topics: Adenine; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Humans; Nucleosides; Organophosphonates; Prodrugs; Tenofovir; Virus Diseases

2013

Trials

1 trial(s) available for tenofovir and cytosine

ArticleYear
Predicted antiviral activity of tenofovir versus abacavir in combination with a cytosine analogue and the integrase inhibitor dolutegravir in HIV-1-infected South African patients initiating or failing first-line ART.
    The Journal of antimicrobial chemotherapy, 2019, 02-01, Volume: 74, Issue:2

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Cytosine; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; HIV Integrase Inhibitors; HIV-1; Humans; Male; Middle Aged; Mutation; Oxazines; Piperazines; Pyridones; South Africa; Tenofovir; Viral Load; Young Adult

2019

Other Studies

12 other study(ies) available for tenofovir and cytosine

ArticleYear
Prevention and inhibition of nasopharyngeal carcinoma growth by antiviral phosphonated nucleoside analogs.
    Cancer research, 2001, Nov-01, Volume: 61, Issue:21

    Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Division; Cidofovir; Cytosine; Epithelial Cells; Growth Inhibitors; Herpesvirus 4, Human; Humans; Mice; Mice, Nude; Nasopharyngeal Neoplasms; Organophosphonates; Organophosphorus Compounds; Tenofovir; Xenograft Model Antitumor Assays

2001
Evaluation of nucleoside phosphonates and their analogs and prodrugs for inhibition of orthopoxvirus replication.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7

    Topics: Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Poxviridae Infections; Prodrugs; Skin; Tenofovir; Virus Replication

2003
Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6).
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:2

    Topics: Adenine; Amino Acid Sequence; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA; Genetic Variation; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Organic Anion Transport Protein 1; Organophosphonates; p-Aminohippuric Acid; Polymorphism, Single Nucleotide; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Complementary; Tenofovir; Xenopus laevis

2005
Acyclic nucleoside phosphonates: past, present and future. Bridging chemistry to HIV, HBV, HCV, HPV, adeno-, herpes-, and poxvirus infections: the phosphonate bridge.
    Biochemical pharmacology, 2007, Apr-01, Volume: 73, Issue:7

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Hepacivirus; Hepatitis B virus; HIV; Humans; Organophosphonates; Papillomaviridae; Poxviridae; Tenofovir; Virus Diseases; Viruses

2007
Renal transport of adefovir, cidofovir, and tenofovir by SLC22A family members (hOAT1, hOAT3, and hOCT2).
    Pharmaceutical research, 2007, Volume: 24, Issue:4

    Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Humans; Kidney; Kinetics; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Organic Cation Transporter 2; Organophosphonates; Probenecid; Tenofovir; Transfection

2007
Gln151 of HIV-1 reverse transcriptase acts as a steric gate towards clinically relevant acyclic phosphonate nucleotide analogues.
    Antiviral therapy, 2008, Volume: 13, Issue:1

    Topics: Adenine; Anti-HIV Agents; Binding Sites; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Viral; Gene Expression Regulation, Viral; HIV Reverse Transcriptase; Models, Molecular; Molecular Structure; Organophosphonates; Protein Conformation; Tenofovir

2008
Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulation.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Adenine; Animals; Cell Line; Cell Survival; CHO Cells; Cidofovir; Cricetinae; Cricetulus; Cytosine; Guanosine; HIV Reverse Transcriptase; Humans; In Vitro Techniques; Kidney; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir

2009
Synthesis and antiviral activity evaluation of acyclic 2'-azanucleosides bearing a phosphonomethoxy function in the side chain.
    Bioorganic & medicinal chemistry, 2009, Jun-01, Volume: 17, Issue:11

    Topics: Acids, Acyclic; Adenine; Antiviral Agents; Aza Compounds; Cidofovir; Cytosine; DNA Viruses; HeLa Cells; Humans; Molecular Structure; Nucleosides; Organophosphonates; RNA Viruses; Tenofovir

2009
Chiral analysis of anti-acquired immunodeficiency syndrome drug, 9-(R)-[2-(phosphonomethoxy)propyl]adenine (tenofovir), and related antiviral acyclic nucleoside phosphonates by CE using beta-CD as chiral selector.
    Electrophoresis, 2009, Volume: 30, Issue:12

    Topics: Adenine; Anti-HIV Agents; beta-Cyclodextrins; Cidofovir; Cytosine; Electrolytes; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Linear Models; Organophosphonates; Purines; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Tenofovir

2009
Scientific report: highlights of 24th ICAR, 8-11 May 2011, Sofia, Bulgaria.
    Antiviral chemistry & chemotherapy, 2011, Oct-07, Volume: 22, Issue:2

    Topics: Adenine; Animals; Antiviral Agents; Arenavirus; Chemistry, Pharmaceutical; Communicable Diseases, Emerging; Cytosine; Flavivirus; Hepacivirus; HIV Seropositivity; Humans; Organophosphonates; Prodrugs; Smallpox; Tenofovir; Virus Replication

2011
Intracellular concentrations determine the cytotoxicity of adefovir, cidofovir and tenofovir.
    Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:1

    Topics: Adenine; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Organic Anion Transport Protein 1; Organophosphonates; Tenofovir; Toxicity Tests

2015
Overcoming the Hydrolytic Lability of a Reaction Intermediate in Production of Protein/Drug Conjugates: Conjugation of an Acyclic Nucleoside Phosphonate to a Model Carrier Protein.
    Molecular pharmaceutics, 2017, 08-07, Volume: 14, Issue:8

    Topics: Adenine; Chromatography, Ion Exchange; Chromatography, Liquid; Cidofovir; Cytosine; HIV; Nucleosides; Organophosphonates; Pharmaceutical Preparations; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tenofovir

2017