tenocyclidine has been researched along with dizocilpine maleate in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (15.79) | 18.7374 |
| 1990's | 45 (78.95) | 18.2507 |
| 2000's | 3 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lemaire, S; Rogers, C | 1 |
| Matsuda, Y; Nonaka, H; Nozawa, M; Toki, S; Tsukuda, E; Yoshida, M | 1 |
| Casalotti, SO; Fauq, A; Kozikowski, AP; Krueger, KE; Tückmantel, W | 1 |
| Ando, K; Kawamoto, I; Matsuda, Y; Sano, H; Toki, S; Yoshida, M | 1 |
| deCosta, BR; Hardwick, WC; McMillan, DE; Rice, KC | 1 |
| Contreras, PC; Farah, JM; Jacobson, AE; Rice, KC | 1 |
| Haring, R; Pellegrini-Giampietro, DE; Scheideler, MA; Zukin, RS; Zukin, SR | 1 |
| Bowen, DM; Cross, AJ; Green, AR; Robinson, TN; Steele, JE | 1 |
| Johnson, KM; Sacaan, AI | 1 |
| Bowen, WD; Reid, AA; Rothman, RB; Setterlund, C | 1 |
| Bao, WL; Sun, FY; Zhang, AZ; Zheng, FC | 1 |
| McCulloch, J | 1 |
| Drian, MJ; Kamenka, JM; Pirat, JL; Privat, A | 1 |
| de Costa, BR; Jacobson, AE; Mattson, MV; Monn, JA; Reid, AA; Rice, KC; Rothman, RB; Thurkauf, A | 1 |
| Bommarito, M; Johnston, MV; McDonald, JW; Silverstein, FS | 1 |
| Boksa, P; Chaudieu, I; Mount, H; Quirion, R | 1 |
| Foucaud, B; Gombos, G | 1 |
| Jacobson, AE; Mattson, MV; Monn, JA; Rice, KC; Thurkauf, A | 1 |
| Besson, MJ; Maurin, Y; Mitrovic, N | 1 |
| Haring, R; Zukin, RS; Zukin, SR | 1 |
| Jacobson, AE; Monn, JA; Reid, AA; Rice, KC; Rothman, RB | 3 |
| Enomoto, R; Katagawa, J; Meguri, H; Ogita, K; Ohgaki, T; Suzuki, T; Uchida, S; Yoneda, Y | 1 |
| Culp, SG; De Souza, EB; Wolfe, SA | 1 |
| Iversen, SD; Oles, RJ; Preston, C; Singh, L; Tricklebank, MD | 1 |
| Denavit-Saubié, M; Foutz, AS | 1 |
| Knight, AR; Wong, EH; Woodruff, GN | 1 |
| Chicheportiche, R; Drian, MJ; Kamenka, JM; Privat, A; Rondouin, G | 1 |
| Braunwalder, AF; Loo, PA; Sills, MA; Williams, M | 1 |
| Johnson, KM; Snell, LD; Yi, SJ | 1 |
| Baba, A; Goji, K; Kawai, N; Klenerová, V; Moroji, T; Sagi, N; Takamori, E; Yamamoto, H; Yamamoto, T | 1 |
| Greenamyre, JT; Porter, RH | 1 |
| Layer, RT; Popik, P; Skolnick, P | 1 |
| Mennini, T; Miari, A; Presti, ML; Rizzi, M; Samanin, R; Vezzani, A | 1 |
| Ferkany, JW; Karbon, EW; Price, CH; Saab, OH; Sweetnam, PM; Wroblewski, JT | 1 |
| Katsuta, K; Kuno, A; Nakanishi, H; Ogita, K; Ohkubo, M; Shirakawa, K; Takasugi, H; Ueda, Y; Yoneda, Y; Yoshida, K | 1 |
| Arckens, L; Orban, GA; Rosier, AM; Vandesande, F | 1 |
| Ogita, K; Suzuki, T; Yoneda, Y | 1 |
| Kovács, KJ; Larson, AA | 1 |
| Akunne, HC; Jacobson, AE; Jiang, Q; Linders, JT; Monn, JA; Porreca, F; Rice, KC; Rothman, RB; Thurkauf, A | 1 |
| Barson, AJ; D'Souza, SW; McConnell, SE; Slater, P | 1 |
| Mechoulam, R; Nadler, V; Sokolovsky, M | 1 |
| Blough, BE; Cadet, JL; Carroll, FI; Emilien, B; Goodman, CB; Mascarella, SW; Pert, A; Rogawski, MA; Subramaniam, S; Thomas, DN | 1 |
| Colpaert, FC; Koek, W; Vignon, J | 1 |
| French, ED; Mura, A; Wang, T | 1 |
| Chen, X; Hurlbert, M; Joseph, DB; Kumar, KN; Michaelis, EK; Michaelis, ML | 1 |
| Mukherjee, J; Ouyang, X; Yang, ZY | 1 |
| Ault, B; Earley, WG; Hildebrand, LM; Kelly, MD; Luttinger, D; Mallamo, JP; Miller, MS; Ward, SJ | 1 |
| Boireau, A; Bordier, F; Doble, A; Durand, G | 1 |
| Fukunaga, R; Kimura, H; Kitamura, Y; Matsuoka, Y; Nabeshima, T; Shimohama, S; Taniguchi, T; Tooyama, I | 1 |
| Brinton, RD; Luu, R; Proffitt, P; Tran, J | 1 |
| Ali, SF; Itzhak, Y | 1 |
| Camarasa, J; Camins, A; Canudas, AM; Escubedo, E; Pallas, M; Pubill, D; Sureda, FX | 1 |
| Espaze, F; Hamon, J; Hirbec, H; Kamenka, JM; Vignon, J | 1 |
| Sun, W; Wessinger, WD | 1 |
| Bloomquist, JR; Geldenhuys, WJ; Malan, SF; Van der Schyf, CJ | 1 |
57 other study(ies) available for tenocyclidine and dizocilpine maleate
| Article | Year |
|---|---|
Characterization of [3H]desmethylimipramine binding in bovine adrenal medulla: interactions with sigma- and (or) phencyclidine-receptor ligands.
Topics: Adrenal Medulla; Animals; Binding Sites; Cattle; Desipramine; Dextromethorphan; Dizocilpine Maleate; Phenazocine; Phencyclidine; Piperidines; Potassium Chloride; Receptors, Opioid, delta; Receptors, Phencyclidine; Tranquilizing Agents | 1992 |
The ES-242s, novel N-methyl-D-aspartate antagonists of microbial origin, interact with both the neurotransmitter recognition site and the ion channel domain.
Topics: Animals; Binding, Competitive; Biological Transport; Calcium; Cells, Cultured; Cyclic GMP; Dizocilpine Maleate; Hippocampus; Ion Channels; Kinetics; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Phencyclidine; Pipecolic Acids; Pyrans; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1992 |
Design of an irreversible affinity ligand for the phencyclidine recognition site on N-methyl-D-aspartate-type glutamate receptors.
Topics: Affinity Labels; Alkylation; Animals; Binding Sites; Binding, Competitive; Cattle; Dizocilpine Maleate; Female; Kinetics; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Thiocyanates; Thiophenes | 1992 |
ES-242-1, a novel compound from Verticillium sp., binds to a site on N-methyl-D-aspartate receptor that is coupled to the channel domain.
Topics: Animals; Bacteria; Binding, Competitive; Centrifugation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Techniques; Dizocilpine Maleate; Dose-Response Relationship, Drug; Fermentation; Kainic Acid; Ketamine; Mitosporic Fungi; Molecular Structure; Phencyclidine; Pyrans; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Soil Microbiology; Solubility; Synaptic Membranes | 1992 |
Effects of drugs that bind to PCP and sigma receptors on punished responding.
Topics: Animals; Buspirone; Dizocilpine Maleate; Haloperidol; Learning; Male; Pentobarbital; Phenazocine; Phencyclidine; Punishment; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1991 |
Phencyclidine increased release of beta-endorphin from anterior lobe of the pituitary.
Topics: alpha-MSH; Animals; Ataxia; Behavior, Animal; beta-Endorphin; Dexamethasone; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Phencyclidine; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains; Sympathomimetics | 1991 |
High efficiency reconstitution of a phencyclidine/MK-801 receptor binding site solubilized from rat forebrain membranes.
Topics: Affinity Labels; Animals; Binding Sites; Binding, Competitive; Cholic Acids; Dizocilpine Maleate; In Vitro Techniques; Male; Membranes; Molecular Weight; Phencyclidine; Photolysis; Prosencephalon; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine; Solubility | 1991 |
A comparison of [3H]MK-801 and N-[1-(2-thienyl)cyclohexyl]-3,4-[3H]piperidine binding to the N-methyl-D-aspartate receptor complex in human brain.
Topics: Aged; Brain; Corpus Striatum; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Glycine; Humans; Male; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Tritium | 1991 |
Regulation of polyamine and magnesium inhibition of the N-methyl-D-aspartate (NMDA) receptor ionophore complex.
Topics: Animals; Biogenic Polyamines; Dizocilpine Maleate; Erythrocyte Membrane; Glutamates; Glutamic Acid; Glycine; In Vitro Techniques; Magnesium; Phencyclidine; Putrescine; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Structure-Activity Relationship | 1991 |
The competitive NMDA receptor antagonist, CPP, allosterically modulates NMDA receptor associated PCP binding sites in the absence of steric hinderance.
Topics: Animals; Dizocilpine Maleate; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Kinetics; Membranes; Molecular Conformation; Phencyclidine; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1990 |
[Antagonistic effects of dextromethorphan on vasoconstriction of phencyclidine in vitro].
Topics: Animals; Biological Assay; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Norepinephrine; Phencyclidine; Rabbits; Vasoconstriction | 1991 |
Ischaemic brain damage--prevention with competitive and non-competitive antagonists of N-methyl-D-aspartate receptors.
Topics: Animals; Cats; Cerebral Arteries; Dextrorphan; Dizocilpine Maleate; Hematoma, Subdural; Ischemic Attack, Transient; Kynurenic Acid; Phencyclidine; Piperazines; Rats; Receptors, N-Methyl-D-Aspartate | 1991 |
Non-competitive antagonists of N-methyl-D-aspartate prevent spontaneous neuronal death in primary cultures of embryonic rat cortex.
Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclohexanes; Cyclohexenes; Dizocilpine Maleate; Embryo, Mammalian; Female; N-Methylaspartate; Neurons; Phencyclidine; Piperidines; Pregnancy; Rats; Rats, Inbred Strains | 1991 |
Specificity of phencyclidine-like drugs and benzomorphan opiates for two high affinity phencyclidine binding sites in guinea pig brain.
Topics: Analgesics; Animals; Benzomorphans; Brain; Dioxolanes; Dizocilpine Maleate; Guinea Pigs; In Vitro Techniques; Kinetics; Ligands; Narcotics; Phencyclidine; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Structure-Activity Relationship | 1990 |
Effects of hypoxia-ischemia and MK-801 treatment on the binding of a phencyclidine analogue in the developing rat brain.
Topics: Animals; Animals, Newborn; Aspartic Acid; Autoradiography; Binding Sites; Brain; Brain Ischemia; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hypoxia; N-Methylaspartate; Phencyclidine; Rats; Rats, Inbred Strains; Tritium | 1990 |
Phencyclidine and related compounds evoked [3H]dopamine release from rat mesencephalic cell cultures by a mechanism independent of the phencyclidine receptor, sigma binding site, or dopamine uptake site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Binding Sites; Cells, Cultured; Dioxolanes; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Guanidines; Mesencephalon; N-Methylaspartate; Neurotransmitter Uptake Inhibitors; Phencyclidine; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Sigma Factor; Tritium | 1990 |
Identification and characterization of a high-affinity glutamate-controlled TCP binding site in rat brain postsynaptic densities.
Topics: Animals; Brain; Cell Membrane; Dizocilpine Maleate; Glutamates; Glutamic Acid; In Vitro Techniques; Kinetics; Phencyclidine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Subcellular Fractions; Synapses; Synaptosomes | 1990 |
Synthesis and structure-activity relationship of C5-substituted analogues of (+-)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine [(+-)-desmethyl-MK801]: ligands for the NMDA receptor-coupled phencyclidine binding site.
Topics: Animals; Binding Sites; Dibenzocycloheptenes; Dizocilpine Maleate; In Vitro Techniques; Ligands; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Regression Analysis; Structure-Activity Relationship | 1990 |
Anticonvulsant effects of antagonists of the N-methyl-D-aspartate receptor complex in a genetic model of epilepsy: the quaking mouse.
Topics: Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Epilepsy; Injections, Intravenous; Male; Mice; Mice, Quaking; Phencyclidine; Physical Stimulation; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1990 |
Photoaffinity labeling and binding studies reveal the existence of two types of phencyclidine receptors in the NCB-20 cell line.
Topics: Animals; Azides; Binding, Competitive; Cell Line; Cricetinae; Dibenzocycloheptenes; Dizocilpine Maleate; Mice; Molecular Weight; Neuroblastoma; Phencyclidine; Photochemistry; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1990 |
Pseudoallosteric modulation by (+)-MK801 of NMDA-coupled phencyclidine binding sites.
Topics: Allosteric Regulation; Allosteric Site; Animals; Binding, Competitive; Brain; Cell Membrane; Dizocilpine Maleate; Guinea Pigs; Kinetics; Ligands; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1990 |
Profiles of [3H]N-[1-(2-thienyl)cyclohexyl]piperidine binding in brain synaptic membranes treated with Triton X-100.
Topics: Animals; Binding, Competitive; Brain; Detergents; Dizocilpine Maleate; Kinetics; Octoxynol; Phencyclidine; Polyethylene Glycols; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Tritium | 1990 |
Sigma-receptors in endocrine organs: identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary.
Topics: Adrenal Glands; Animals; Autoradiography; Brain Chemistry; Cell Membrane; Dibenzocycloheptenes; Dizocilpine Maleate; Female; Haloperidol; Hypophysectomy; Male; Ovary; Phencyclidine; Piperidines; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Testis; Tissue Distribution | 1989 |
The behavioural effects of MK-801: a comparison with antagonists acting non-competitively and competitively at the NMDA receptor.
Topics: Animals; Anticonvulsants; Aspartic Acid; Behavior, Animal; Binding, Competitive; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ketamine; Male; Motor Activity; N-Methylaspartate; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1989 |
Differentiation of phencyclidine and sigma receptor types affecting the central inspiratory termination mechanism in cat.
Topics: Animals; Brain Stem; Cats; Decerebrate State; Dextrorphan; Dibenzocycloheptenes; Dizocilpine Maleate; Guanidines; Phencyclidine; Phrenic Nerve; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Respiration | 1989 |
The psychotomimetic drug phencyclidine labels two high affinity binding sites in guinea pig brain: evidence for N-methyl-D-aspartate-coupled and dopamine reuptake carrier-associated phencyclidine binding sites.
Topics: Acetylcholine; Animals; Binding Sites; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Guinea Pigs; In Vitro Techniques; Kinetics; Magnesium; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1989 |
Characterization of NMDA-coupled and dopamine reuptake carrier coupled [3H]-TCP binding sites in guinea pig brain.
Topics: Animals; Binding, Competitive; Brain; Carrier Proteins; Culture Techniques; Dibenzocycloheptenes; Dizocilpine Maleate; Dopamine; Dopamine Plasma Membrane Transport Proteins; Guinea Pigs; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1989 |
[3H]MK-801 labels a site on the N-methyl-D-aspartate receptor channel complex in rat brain membranes.
Topics: Animals; Anticonvulsants; Brain; Cations, Divalent; Cell Membrane; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Kinetics; Male; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tissue Distribution; Tritium | 1988 |
Non-competitive antagonists of N-methyl-D-aspartate receptors protect cortical and hippocampal cell cultures against glutamate neurotoxicity.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; Neurotoxins; Phencyclidine; Prodrugs; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
The novel anticonvulsant MK-801 interacts with central phencyclidine recognition sites in rat brain.
Topics: Animals; Brain Chemistry; Convulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Phencyclidine; Rats; Receptors, Neurotransmitter; Receptors, Phencyclidine | 1987 |
Comparison of the effects of MK-801 and phencyclidine on catecholamine uptake and NMDA-induced norepinephrine release.
Topics: Animals; Aspartic Acid; Catecholamines; Dibenzocycloheptenes; Dizocilpine Maleate; Hippocampus; In Vitro Techniques; N-Methylaspartate; Norepinephrine; Phencyclidine; Rats | 1988 |
Sigma ligands indirectly modulate the NMDA receptor-ion channel complex on intact neuronal cells via sigma 1 site.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Dizocilpine Maleate; Glutamic Acid; Ion Channels; Ligands; Neurons; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1995 |
Regional variations in the pharmacology of NMDA receptor channel blockers: implications for therapeutic potential.
Topics: Acetamides; Animals; Antiparkinson Agents; Autoradiography; Binding, Competitive; Brain; Dizocilpine Maleate; Ion Channels; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tissue Distribution | 1995 |
The putative anti-addictive drug ibogaine is a competitive inhibitor of [3H]MK-801 binding to the NMDA receptor complex.
Topics: Animals; Binding, Competitive; Dizocilpine Maleate; Ibogaine; In Vitro Techniques; Ion Channels; Ligands; Phencyclidine; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate | 1994 |
Adaptive changes in the NMDA receptor complex in rat hippocampus after chronic treatment with CGP 39551.
Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Dizocilpine Maleate; Glutamic Acid; Hippocampus; Kynurenic Acid; Male; Norepinephrine; Phencyclidine; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1994 |
The envelope glycoprotein of HIV-1 alters NMDA receptor function.
Topics: Animals; Calcium Channel Blockers; Cells, Cultured; Dizocilpine Maleate; Electrophysiology; HIV Envelope Protein gp120; N-Methylaspartate; Oocytes; Phencyclidine; Pipecolic Acids; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Xenopus | 1993 |
Behavioral studies on FR115427, a novel selective N-methyl-D-aspartate antagonist.
Topics: Animals; Anticonvulsants; Behavior, Animal; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; In Vitro Techniques; Isoquinolines; Male; Membranes; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Motor Activity; Phencyclidine; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tetrahydroisoquinolines | 1995 |
Laminar distribution of NMDA receptors in cat and monkey visual cortex visualized by [3H]-MK-801 binding.
Topics: Animals; Autoradiography; Binding, Competitive; Cats; Dizocilpine Maleate; Female; Freeze Drying; Glutamates; Glutamic Acid; Macaca fascicularis; Male; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Vision, Ocular; Visual Cortex | 1993 |
Potentiation by polyamines of an interaction of noncompetitive antagonists at the N-methyl-D-aspartate receptor ionophore complex with phosphatidylserine.
Topics: Animals; Brain; Calmodulin; Dizocilpine Maleate; Glutamates; Glutamic Acid; Glycine; Illicit Drugs; Kinetics; Phencyclidine; Phosphatidylserines; Phospholipids; Polyamines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptic Membranes; Tritium | 1993 |
Density of NMDA-coupled and uncoupled 1-[1-(2-[3H]thienyl) cyclohexyl]piperidine recognition sites in the brain and spinal cord: differential effects of NMDA agonists and antagonists.
Topics: Animals; Binding Sites; Brain; Brain Chemistry; Dizocilpine Maleate; Glutamic Acid; Glycine; Haloperidol; Male; Mice; N-Methylaspartate; Phencyclidine; Spinal Cord; Tritium | 1994 |
An electrophilic affinity ligand based on (+)-MK801 distinguishes PCP site 1 from PCP site 2.
Topics: Affinity Labels; Animals; Brain; Cell Membrane; Cerebral Ventricles; Dizocilpine Maleate; Illicit Drugs; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Phencyclidine; Receptors, Phencyclidine | 1994 |
Postnatal changes in N-methyl-D-aspartate receptor binding and stimulation by glutamate and glycine of [3H]-MK-801 binding in human temporal cortex.
Topics: Adult; Aging; Cerebral Cortex; Dizocilpine Maleate; Female; Glutamates; Glutamic Acid; Glycine; Humans; In Vitro Techniques; Infant; Infant, Newborn; Male; Phencyclidine; Proteins; Receptors, N-Methyl-D-Aspartate; Stimulation, Chemical; Sudden Infant Death; Temporal Lobe | 1993 |
The non-psychotropic cannabinoid (+)-(3S,4S)-7-hydroxy-delta 6- tetrahydrocannabinol 1,1-dimethylheptyl (HU-211) attenuates N-methyl-D-aspartate receptor-mediated neurotoxicity in primary cultures of rat forebrain.
Topics: Animals; Calcium Channel Blockers; Cell Death; Cells, Cultured; Dizocilpine Maleate; Dronabinol; L-Lactate Dehydrogenase; Neurons; Phencyclidine; Prosencephalon; Rats; Receptors, N-Methyl-D-Aspartate | 1993 |
RTI-4793-14, a new ligand with high affinity and selectivity for the (+)-MK801-insensitive [3H]1-]1-(2-thienyl)cyclohexyl]piperidine binding site (PCP site 2) of guinea pig brain.
Topics: Animals; Biogenic Monoamines; Brain; Dizocilpine Maleate; Electrophysiology; Guinea Pigs; In Vitro Techniques; Indenes; Ligands; Male; Microdialysis; Phencyclidine; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Phencyclidine; Synaptosomes | 1994 |
Effects of phencyclidine-type drugs in rats discriminating fentanyl from saline: pharmacological and behavioral characterization of intermediate levels of drug lever selection.
Topics: Animals; Conditioning, Operant; Discrimination Learning; Dizocilpine Maleate; Fentanyl; Ketamine; Male; Phencyclidine; Rats; Rats, Wistar; Reinforcement, Psychology | 1993 |
MK-801, phencyclidine (PCP), and PCP-like drugs increase burst firing in rat A10 dopamine neurons: comparison to competitive NMDA antagonists.
Topics: Action Potentials; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Illicit Drugs; Male; N-Methylaspartate; Neurons; Phencyclidine; Pipecolic Acids; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stereotaxic Techniques; Tegmentum Mesencephali; Vibrissae | 1993 |
Ethanol-induced inhibition of [3H]thienylcyclohexylpiperidine (TCP) binding to NMDA receptors in brain synaptic membranes and to a purified protein complex.
Topics: Animals; Brain Chemistry; Dizocilpine Maleate; Dopamine Antagonists; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Haloperidol; Illicit Drugs; Kinetics; Male; Membrane Proteins; N-Methylaspartate; Phencyclidine; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sensitivity and Specificity; Spermidine; Synaptic Membranes; Tritium | 1996 |
Synthesis, radiosynthesis, and biological evaluation of fluorinated thienylcyclohexyl piperidine derivatives as potential radiotracers for the NMDA receptor-linked calcium ionophore.
Topics: Animals; Brain; Calcium Channels; Dizocilpine Maleate; Fluorine Radioisotopes; Indicators and Reagents; Isotope Labeling; Macaca mulatta; Magnetic Resonance Spectroscopy; Male; Molecular Structure; Phencyclidine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Tissue Distribution; Tomography, Emission-Computed | 1996 |
WIN 63480, a hydrophilic TCP-site ligand, has reduced agonist-independent NMDA ion channel access compared to MK-801 and phencyclidine.
Topics: Animals; Binding Sites; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Kynurenic Acid; Membrane Potentials; Mice; Phencyclidine; Quinolizines; Receptors, N-Methyl-D-Aspartate; Transfection; Xenopus laevis | 1995 |
The antidepressant metapramine is a low-affinity antagonist at N-methyl-D-aspartic acid receptors.
Topics: Animals; Antidepressive Agents, Tricyclic; Binding Sites; Binding, Competitive; Cell Membrane; Cerebral Cortex; Cyclic GMP; Dibenzazepines; Dizocilpine Maleate; Glycine; In Vitro Techniques; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate | 1996 |
In vivo hypoxia-induced neuronal damage in dentate gyrus of rat hippocampus: changes in NMDA receptors and the effect of MK-801.
Topics: Animals; Dentate Gyrus; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hippocampus; Hypoxia, Brain; Immunohistochemistry; Male; Neurons; Phencyclidine; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Tritium | 1997 |
Equilin, a principal component of the estrogen replacement therapy premarin, increases the growth of cortical neurons via an NMDA receptor-dependent mechanism.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cells, Cultured; Cerebral Cortex; Cognition; Culture Media, Serum-Free; Dizocilpine Maleate; Equilin; Estradiol; Estrogen Replacement Therapy; Estrogens; Estrogens, Conjugated (USP); Excitatory Amino Acid Antagonists; Growth Substances; Microscopy, Video; Neurons; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate | 1997 |
Effect of ibogaine on the various sites of the NMDA receptor complex and sigma binding sites in rat brain.
Topics: Animals; Binding Sites; Brain; Dizocilpine Maleate; Ibogaine; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1998 |
Effect of PCP and sigma ligands on both noradrenaline- and electrically-induced contractions and on [3H]-noradrenaline uptake in rat vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Dextromethorphan; Dizocilpine Maleate; Dopamine Agonists; Electric Stimulation; Excitatory Amino Acid Antagonists; Ligands; Male; Muscle Contraction; Neuroprotective Agents; Norepinephrine; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Phencyclidine; Receptors, sigma; Tritium; Vas Deferens | 1998 |
The low affinity PCP sites in the rat cerebellum not only bind TCP-like but also BTCP-like structures.
Topics: Animals; Binding, Competitive; Cerebellum; Dizocilpine Maleate; Dopamine Agonists; Excitatory Amino Acid Antagonists; Kinetics; Male; Membranes; Neostriatum; Phencyclidine; Prosencephalon; Rats; Rats, Wistar; Receptors, Phencyclidine; Structure-Activity Relationship | 2000 |
Characterization of the non-competitive antagonist binding site of the NMDA receptor in dark Agouti rats.
Topics: Animals; Binding, Competitive; Brain; Dextromethorphan; Dioxolanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Ketamine; N-Methylaspartate; Phenazocine; Phencyclidine; Piperidines; Rats; Rats, Mutant Strains; Receptors, N-Methyl-D-Aspartate; Scintillation Counting; Tritium | 2004 |
Structure-activity relationships of pentacycloundecylamines at the N-methyl-d-aspartate receptor.
Topics: Amines; Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ion Channels; Male; Mice; Mice, Inbred ICR; Models, Molecular; Phencyclidine; Piperidines; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Synaptosomes; Thiophenes | 2007 |