Page last updated: 2024-09-04

tempol and aspirin

tempol has been researched along with aspirin in 3 studies

Compound Research Comparison

Studies
(tempol)
Trials
(tempol)
Recent Studies (post-2010)
(tempol)
Studies
(aspirin)
Trials
(aspirin)
Recent Studies (post-2010) (aspirin)
1901548,9476,81713,778

Protein Interaction Comparison

ProteinTaxonomytempol (IC50)aspirin (IC50)
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.35
Integrin beta-3Homo sapiens (human)5
Prostaglandin G/H synthase 1Ovis aries (sheep)0.8252
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)1.375
Integrin alpha-IIbHomo sapiens (human)5
Prostaglandin G/H synthase 1Homo sapiens (human)2.271
Substance-P receptorCavia porcellus (domestic guinea pig)2.4
Prostaglandin G/H synthase 2Homo sapiens (human)2.15
Urotensin-2 receptorRattus norvegicus (Norway rat)0.3
4-aminobutyrate aminotransferase, mitochondrialRattus norvegicus (Norway rat)2.4
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.35
Prostaglandin G/H synthase 2Ovis aries (sheep)2.4081

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bi, L; Bi, W; Bi, Y; Gao, X; Itagaki, Y; Li, M; Li, X; Wang, Z; Xue, P; Zhang, Y1
Bammert, C; Bi, L; Bi, W; Bi, Y; Gao, X; Hou, S; Jockusch, S; Legalley, TD; Li, P; Michael Gibson, K; Zhang, Y1
Barnett, NL; Bottle, SE; Fairfull-Smith, KE; Jensen, RT; Moody, TW; Rayner, CL; Ridnour, LA; Thomas, K; Tong, J; Wink, DA1

Other Studies

3 other study(ies) available for tempol and aspirin

ArticleYear
Novel TEMPO-PEG-RGDs conjugates remediate tissue damage induced by acute limb ischemia/reperfusion.
    Journal of medicinal chemistry, 2012, May-10, Volume: 55, Issue:9

    Topics: Animals; Cyclic N-Oxides; Free Radical Scavengers; Hindlimb; Histocytochemistry; Malondialdehyde; Muscle, Skeletal; Oligopeptides; Oxidative Stress; Platelet Aggregation; Polyethylene Glycols; Rats; Reperfusion Injury; Superoxide Dismutase

2012
Indole-TEMPO conjugates alleviate ischemia-reperfusion injury via attenuation of oxidative stress and preservation of mitochondrial function.
    Bioorganic & medicinal chemistry, 2017, 05-01, Volume: 25, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Cyclic N-Oxides; Cytochromes c; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Intestine, Small; Lipid Peroxidation; Male; Mice, Inbred ICR; Mitochondria; Molecular Dynamics Simulation; Neutrophil Infiltration; Oxidative Stress; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Tumor Necrosis Factor-alpha

2017
Design, synthesis and biological evaluation of hybrid nitroxide-based non-steroidal anti-inflammatory drugs.
    European journal of medicinal chemistry, 2018, Mar-10, Volume: 147

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antioxidants; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Nitrogen Oxides; Oxidative Stress; Reactive Oxygen Species; Structure-Activity Relationship

2018