tempo and arginyl-glycyl-aspartic-acid

tempo has been researched along with arginyl-glycyl-aspartic-acid* in 1 studies

Other Studies

1 other study(ies) available for tempo and arginyl-glycyl-aspartic-acid

Article	Year
Novel TEMPO-PEG-RGDs conjugates remediate tissue damage induced by acute limb ischemia/reperfusion. Journal of medicinal chemistry, 2012, May-10, Volume: 55, Issue:9 We have recently developed new Tempo-PEG-RGDs conjugates and have quantitatively examined their antithrombotic and antioxidant capabilities. These compounds were therapeutically beneficial when characterized in both in vitro platelet aggregation assays and a rat model of arterial thrombosis. Moreover, these compounds demonstrated significant protection from organ damage in a rat model of ischemia/reperfusion. Our data indicate that Tempo-PEG-RGDs represent a new class of adjuvants with therapeutic efficacy in acute and transient ischemic damage. Topics: Animals; Cyclic N-Oxides; Free Radical Scavengers; Hindlimb; Histocytochemistry; Malondialdehyde; Muscle, Skeletal; Oligopeptides; Oxidative Stress; Platelet Aggregation; Polyethylene Glycols; Rats; Reperfusion Injury; Superoxide Dismutase	2012

Article

Year

Novel TEMPO-PEG-RGDs conjugates remediate tissue damage induced by acute limb ischemia/reperfusion.

Journal of medicinal chemistry, 2012, May-10, Volume: 55, Issue:9

We have recently developed new Tempo-PEG-RGDs conjugates and have quantitatively examined their antithrombotic and antioxidant capabilities. These compounds were therapeutically beneficial when characterized in both in vitro platelet aggregation assays and a rat model of arterial thrombosis. Moreover, these compounds demonstrated significant protection from organ damage in a rat model of ischemia/reperfusion. Our data indicate that Tempo-PEG-RGDs represent a new class of adjuvants with therapeutic efficacy in acute and transient ischemic damage.

Topics: Animals; Cyclic N-Oxides; Free Radical Scavengers; Hindlimb; Histocytochemistry; Malondialdehyde; Muscle, Skeletal; Oligopeptides; Oxidative Stress; Platelet Aggregation; Polyethylene Glycols; Rats; Reperfusion Injury; Superoxide Dismutase

2012