temozolomide has been researched along with vorinostat in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 14 (93.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Liu, Y; Xu, Z; Zhao, SJ | 1 |
| Carlson, BL; Cen, L; Decker, PA; Gupta, SK; Kitange, GJ; Lomberk, GA; Mladek, AC; Pokorny, JL; Sarkaria, JN; Schroeder, MA; Urrutia, RA; Wu, W | 1 |
| Ames, MM; Chang, SM; Cloughesy, TF; Desideri, S; Drappatz, J; Espinoza-Delgado, I; Gilbert, MR; Kuhn, JG; Lamborn, KR; Lassman, AB; Lee, EQ; Lieberman, FS; McGovern, RM; Prados, MD; Puduvalli, VK; Reid, JM; Robins, HI; Wen, PY; Xu, J; Ye, X; Yung, WK | 1 |
| Ahern, C; Ames, MM; Blaney, SM; Fouladi, M; Gilbertson, RJ; Horton, T; Hummel, TR; Ingle, AM; McGovern, RM; Reid, JM; Wagner, L; Weigel, B | 1 |
| Collier, AB; Gresh, RC; Kamara, DF; Kolb, EA; Sampson, VB; Vetter, NS | 1 |
| Chang, WC; Chuang, JY; Hsu, TI; Ko, CY; Lin, CH | 1 |
| Ahluwalia, MS; Anderson, SK; Ballman, KV; Buckner, JC; Cerhan, J; Galanis, E; Gerstner, ER; Giannini, C; Grossman, SA; Jaeckle, K; Lee, EQ; Lesser, GJ; Ligon, KL; Loboda, A; Miller, CR; Moore, DF; Nebozhyn, M; Prados, M; Sarkaria, JN; Schiff, D; Wen, PY | 1 |
| Desjardins, A; Friedman, HS; Herndon, JE; Lipp, ES; McSherry, F; Miller, E; Peters, KB; Reardon, DA | 1 |
| Abrey, LE; Alexander, BM; Arrillaga-Romany, I; Batchelor, T; Butowski, N; Chang, S; Chinot, O; Cloughesy, TF; Colen, R; Colman, H; de Groot, J; Ellingson, BM; Galanis, E; Garcia, J; Gerstner, ER; Henriksson, R; Huang, RY; Kaufmann, TJ; Ligon, KL; Mason, WP; Mehta, A; Mellinghoff, I; Nelson, SJ; Nishikawa, R; Pope, WB; Prados, M; Reardon, D; Saran, F; Taylor, JW; Wen, PY; Wick, W; Young, RJ | 1 |
| Agnes, JP; de Souza, PO; Delgobo, M; Gonçalves, RM; Heimfarth, L; Lenz, G; Moreira, JCF; Thomé, MP; Zanotto-Filho, A | 1 |
| Batsaikhan, B; Chiu, SP; Huang, HM; Wang, JY | 1 |
2 review(s) available for temozolomide and vorinostat
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles | 2019 |
5 trial(s) available for temozolomide and vorinostat
| Article | Year |
|---|---|
Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Female; Glioma; Humans; Hydroxamic Acids; Male; Middle Aged; Neoplasm Grading; Temozolomide; Treatment Outcome; Vorinostat | 2012 |
A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Child; Child, Preschool; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Dose-Response Relationship, Drug; Female; Histones; Humans; Hydroxamic Acids; Leukocytes, Mononuclear; Male; Maximum Tolerated Dose; Neutropenia; Promoter Regions, Genetic; Recurrence; Spinal Cord Neoplasms; Temozolomide; Thrombocytopenia; Tumor Suppressor Proteins; Vorinostat | 2013 |
Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Cohort Studies; Female; Follow-Up Studies; Glioblastoma; Humans; Male; Maximum Tolerated Dose; Middle Aged; Prognosis; Survival Rate; Temozolomide; Vorinostat; Young Adult | 2018 |
Phase I/II trial of vorinostat, bevacizumab, and daily temozolomide for recurrent malignant gliomas.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Dose-Response Relationship, Drug; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Survival Analysis; Temozolomide; Treatment Outcome; Vorinostat | 2018 |
Validation of postoperative residual contrast-enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Contrast Media; Female; Follow-Up Studies; Glioblastoma; Humans; Image Enhancement; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm, Residual; Postoperative Care; Prognosis; Retrospective Studies; Survival Rate; Temozolomide; Vorinostat | 2018 |
8 other study(ies) available for temozolomide and vorinostat
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Inhibition of histone deacetylation potentiates the evolution of acquired temozolomide resistance linked to MGMT upregulation in glioblastoma xenografts.
Topics: Acetylation; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Dacarbazine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Kaplan-Meier Estimate; Methylation; Mice; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Temozolomide; Tumor Suppressor Proteins; Up-Regulation; Vorinostat; Xenograft Model Antitumor Assays | 2012 |
Vorinostat Enhances Cytotoxicity of SN-38 and Temozolomide in Ewing Sarcoma Cells and Activates STAT3/AKT/MAPK Pathways.
Topics: Acetylation; Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dacarbazine; DNA Damage; G1 Phase Cell Cycle Checkpoints; Heterocyclic Compounds, 3-Ring; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Irinotecan; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Sarcoma, Ewing; Signal Transduction; STAT3 Transcription Factor; Temozolomide; Tumor Suppressor Protein p53; Vorinostat | 2015 |
MDM2 Degrades Deacetylated Nucleolin Through Ubiquitination to Promote Glioma Stem-Like Cell Enrichment for Chemotherapeutic Resistance.
Topics: Acetylation; Brain Neoplasms; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioma; Histone Deacetylase Inhibitors; Humans; JNK Mitogen-Activated Protein Kinases; Models, Biological; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Nucleolin; Phosphoproteins; Phosphorylation; Proteolysis; Proto-Oncogene Proteins c-mdm2; RNA-Binding Proteins; RNA, Messenger; Spheroids, Cellular; STAT3 Transcription Factor; Temozolomide; Ubiquitination; Vorinostat | 2018 |
Late autophagy inhibitor chloroquine improves efficacy of the histone deacetylase inhibitor SAHA and temozolomide in gliomas.
Topics: Animals; Antimalarials; Antineoplastic Agents; Astrocytes; Autophagy; Beclin-1; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Chloroquine; Drug Therapy, Combination; Gene Knockdown Techniques; Humans; Rats; Rats, Wistar; Temozolomide; Vorinostat | 2019 |
Application of Electric Cell-Substrate Impedance Sensing to Investigate the Cytotoxic Effects of Andrographolide on U-87 MG Glioblastoma Cell Migration and Apoptosis.
Topics: Apoptosis; Biosensing Techniques; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Diterpenes; Electric Impedance; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Proto-Oncogene Proteins c-bcl-2; Temozolomide; Vorinostat | 2019 |