Page last updated: 2024-08-16

temozolomide and thalidomide

temozolomide has been researched along with thalidomide in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (3.03)	18.2507
2000's	20 (60.61)	29.6817
2010's	12 (36.36)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Burton, E; Prados, M	1
Hwu, WJ	1
Hwu, WJ; Lis, E; Panageas, KS; Raizer, J	1
Lichtman, SM; Skirvin, JA	1
Chapman, PB; Houghton, AN; Hwu, WJ; Krown, SE; Livingston, PO; Menell, JH; Panageas, KS; Quinn, CJ; Williams, LJ	1
Arance, A; Ashcroft, L; Clamp, A; Danson, S; Hodgetts, J; Lomax, L; Lorigan, P; Middleton, MR; Ranson, M; Thatcher, N	1
Chapman, PB; Foster, T; Houghton, AN; Hwu, WJ; Krown, SE; Lamb, LA; Livingston, PO; Menell, JH; Merrell, J; Panageas, KS; Quinn, CJ; Williams, LJ; Wolchok, JD	1
Chang, SM; Lamborn, KR; Larson, D; Malec, M; Nicholas, MK; Page, M; Prados, MD; Rabbitt, J; Sneed, P; Wara, W	1
Chapman, PB; Houghton, AN; Hwu, WJ; Krown, SE; Lamb, LA; Lis, E; Livingston, PO; Menell, JH; Merrell, J; Panageas, KS; Williams, LJ; Wolchok, JD	1
Jeon, HJ; Kim, H; Kim, JH; Kim, JS; Kim, JT; Kim, MH; Kim, YJ; Lee, DS; Nam, DH; Park, SY; Shin, T; Son, MJ; Song, HS	1
Clark, JW; Enzinger, PC; Fuchs, CS; Kulke, MH; Michelini, A; Muzikansky, A; Ryan, DP; Stuart, K; Vincitore, M	1
Kerr, C	1
Itasaka, S; Kim, JT; Lee, JI; Nam, DH	1
Arce-Lara, C; Kloecker, GH; Laber, DA; McMasters, KM; Miller, DM; Okeke, RI; Schonard, CL; Taft, BS	1
Haluska, FG; Hodgson, L; Houghton, AN; Hwu, WJ; Krown, SE; Niedzwiecki, D	1
Abrey, LE; Chang, SM; Cloughesy, TF; Conrad, CA; DeAngelis, LM; Gilbert, MR; Greenberg, H; Groves, MD; Hess, KR; Lamborn, KR; Liu, TJ; Peterson, P; Prados, MD; Puduvalli, VK; Schiff, D; Tremont-Lukats, IW; Wen, PY; Yung, WK	1
Khan, MI; Kloecker, GH; Laber, DA; Salvador, C; Schonard, C; Taft, BS	1
Batchelor, TT; Black, PM; Ciampa, A; Doherty, L; Drappatz, J; Folkman, J; Gigas, DC; Henson, JW; Kesari, S; Kieran, M; Laforme, A; Ligon, KL; Longtine, JA; Muzikansky, A; Ramakrishna, N; Schiff, D; Weaver, S; Wen, PY	1
Agarwala, S; Atkins, MB; Clark, JI; Curti, B; Dutcher, JP; Ernstoff, MS; Lawson, D; Logan, T; Margolin, KA; Sosman, JA; Weiss, G	1
Clamp, A; Danson, S; Lorigan, P; Margison, GP; Middleton, MR; Sabharwal, A; Thatcher, N; Waters, R	1
Gao, S; Ji, YW; Pan, Q; Yang, XJ; Zhang, WG	1
Clark, JI; Da Silva, DM; Flaherty, LE; Hutchins, LF; Kast, WM; Liu, PY; Moon, J; Sondak, VK; Sosman, JA; Thompson, JA	1
Cho, BK; Jung, HL; Kim, CY; Kim, IA; Kim, IH; Kim, SK; Lee, MJ; Lee, MM; Phi, JH; Wang, KC	1
Chang, E; Colman, H; Conrad, C; de Groot, J; Giglio, P; Gilbert, MR; Gonzalez, J; Groves, MD; Hess, K; Hunter, K; Levin, V; Mahajan, A; Puduvalli, V; Woo, S; Yung, WK	1
Bodoky, G; Pregun, I; Rácz, K; Tulassay, Z	1
Cao, KI; Kirova, YM	1
Aldape, KD; Chang, EL; Colman, H; Conrad, CA; De Groot, JF; Fisch, MJ; Floyd, JD; Giglio, P; Gilbert, MR; Gonzalez, J; Groves, MD; Hess, KR; Hsu, SH; Lagrone, LW; Levin, VA; Loghin, ME; Mahajan, A; Penas-Prado, M; Puduvalli, VK; Salacz, ME; Volas-Redd, G; Woo, SY; Yung, WK	1
Abdel-Rahman, O; Fouad, M	1
Burman, P; Dekkers, OM; McCormack, A; Petersenn, S; Popovic, V; Raverot, G; Trouillas, J	1
Bharia, S; Burma, S; Damanwalla, Z; Gerber, DE; Gong, K; Guo, G; Habib, AA; Hatanpaa, KJ; Mickey, BE; Mukherjee, B; Pan, E; Panchani, N; Patel, TR; Puliyappadamba, VT; Sarkaria, JN; Zhao, D	1

Reviews

7 review(s) available for temozolomide and thalidomide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
New chemotherapy options for the treatment of malignant gliomas. Current opinion in oncology, 1999, Volume: 11, Issue:3 Topics: Adult; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Clinical Trials as Topic; Dacarbazine; Enzyme Inhibitors; Glioma; Humans; Irinotecan; Neovascularization, Pathologic; Oligodendroglioma; Protease Inhibitors; Signal Transduction; Temozolomide; Thalidomide	1999
New approaches in the treatment of metastatic melanoma: thalidomide and temozolomide. Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:12 Suppl 1 Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Temozolomide; Thalidomide	2000
Pharmacokinetic considerations of oral chemotherapy in elderly patients with cancer. Drugs & aging, 2002, Volume: 19, Issue:1 Topics: Administration, Oral; Aged; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Complementary Therapies; Cytochrome P-450 Enzyme System; Dacarbazine; Etoposide; Humans; Idarubicin; Neoplasms; Tamoxifen; Temozolomide; Thalidomide; Topotecan	2002
[Carcinoid tumors]. Orvosi hetilap, 2010, Nov-14, Volume: 151, Issue:46 Topics: 3-Iodobenzylguanidine; Antineoplastic Agents; Biomarkers, Tumor; Bronchial Neoplasms; Carcinoid Tumor; Chromogranin A; Clinical Trials as Topic; Dacarbazine; Early Detection of Cancer; Gastrointestinal Neoplasms; Heterocyclic Compounds; Humans; Hydroxyindoleacetic Acid; Lung Neoplasms; Organometallic Compounds; Prevalence; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Somatostatin; Temozolomide; Thalidomide; TOR Serine-Threonine Kinases; Treatment Outcome	2010
[Radiotherapy plus concomitant systemic therapies for patients with brain metastases from breast cancer]. Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2014, Volume: 18, Issue:3 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Breast Neoplasms; Capecitabine; Chemotherapy, Adjuvant; Cisplatin; Clinical Trials, Phase II as Topic; Dacarbazine; Deoxycytidine; Female; Fluorouracil; Humans; Lapatinib; Protein Kinase Inhibitors; Quinazolines; Radiotherapy, Adjuvant; Receptor, ErbB-2; Temozolomide; Thalidomide; Topoisomerase I Inhibitors; Topotecan; Trastuzumab; Vinblastine; Vinorelbine	2014
Temozolomide-based combination for advanced neuroendocrine neoplasms: a systematic review of the literature. Future oncology (London, England), 2015, Volume: 11, Issue:8 Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Dacarbazine; Everolimus; Humans; Neuroendocrine Tumors; Octreotide; Temozolomide; Thalidomide	2015

Trials

16 trial(s) available for temozolomide and thalidomide

Article	Year
Temozolomide plus thalidomide in patients with advanced melanoma: results of a dose-finding trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Jun-01, Volume: 20, Issue:11 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Dose-Response Relationship, Drug; Female; Humans; Male; Melanoma; Middle Aged; Survival Rate; Temozolomide; Thalidomide	2002
Randomized phase II study of temozolomide given every 8 hours or daily with either interferon alfa-2b or thalidomide in metastatic malignant melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-01, Volume: 21, Issue:13 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease Progression; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Recombinant Proteins; Skin Neoplasms; Survival; Temozolomide; Thalidomide	2003
Phase II study of temozolomide plus thalidomide for the treatment of metastatic melanoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Sep-01, Volume: 21, Issue:17 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Dose-Response Relationship, Drug; Female; Humans; Male; Melanoma; Middle Aged; Survival Analysis; Temozolomide; Thalidomide; Treatment Outcome	2003
Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme. International journal of radiation oncology, biology, physics, 2004, Oct-01, Volume: 60, Issue:2 Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Dacarbazine; Drug Administration Schedule; Female; Follow-Up Studies; Glioblastoma; Humans; Male; Middle Aged; Temozolomide; Thalidomide	2004
Temozolomide plus thalidomide in patients with brain metastases from melanoma: a phase II study. Cancer, 2005, Jun-15, Volume: 103, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Staging; Skin Neoplasms; Survival Rate; Temozolomide; Thalidomide; Treatment Outcome	2005
Phase II study of temozolomide and thalidomide in patients with metastatic neuroendocrine tumors. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jan-20, Volume: 24, Issue:3 Topics: Adrenal Gland Neoplasms; Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Carcinoid Tumor; Carcinoma, Islet Cell; Dacarbazine; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neuroendocrine Tumors; Pancreatic Neoplasms; Pheochromocytoma; Survival Analysis; Temozolomide; Thalidomide; Treatment Outcome	2006
A phase II study of extended dose temozolomide and thalidomide in previously treated patients with metastatic melanoma. Journal of cancer research and clinical oncology, 2006, Volume: 132, Issue:9 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Disease Progression; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Skin Neoplasms; Survival Rate; Temozolomide; Thalidomide; Treatment Outcome	2006
Phase II study of temozolomide and thalidomide in patients with metastatic melanoma in the brain: high rate of thromboembolic events (CALGB 500102). Cancer, 2006, Oct-15, Volume: 107, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Humans; Melanoma; Middle Aged; Pulmonary Embolism; Skin Neoplasms; Survival Rate; Temozolomide; Thalidomide; Treatment Failure; Venous Thrombosis; Withholding Treatment	2006
A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme. Journal of neuro-oncology, 2007, Volume: 81, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Disease-Free Survival; Enzyme-Linked Immunosorbent Assay; Female; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; North America; Survival Analysis; Temozolomide; Thalidomide	2007
A phase I study of thalidomide, capecitabine and temozolomide in advanced cancer. Cancer biology & therapy, 2007, Volume: 6, Issue:6 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Combined Modality Therapy; Dacarbazine; Deoxycytidine; Disease Progression; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Temozolomide; Thalidomide; Treatment Outcome	2007
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults. Neuro-oncology, 2008, Volume: 10, Issue:3 Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Celecoxib; Dacarbazine; Disease-Free Survival; DNA Methylation; Endostatins; Female; Fibroblast Growth Factor 2; Glioblastoma; Humans; Kaplan-Meier Estimate; Male; Middle Aged; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Promoter Regions, Genetic; Pyrazoles; Sulfonamides; Temozolomide; Thalidomide; Thrombospondins; Vascular Endothelial Growth Factor A	2008
Temozolomide, thalidomide, and whole brain radiation therapy for patients with brain metastasis from metastatic melanoma: a phase II Cytokine Working Group study. Cancer, 2008, Oct-15, Volume: 113, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Temozolomide; Thalidomide	2008
Phase 2 trial of combination thalidomide plus temozolomide in patients with metastatic malignant melanoma: Southwest Oncology Group S0508. Cancer, 2010, Jan-15, Volume: 116, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Skin Neoplasms; Temozolomide; Thalidomide	2010
A prospective study of temozolomide plus thalidomide during and after radiation therapy for pediatric diffuse pontine gliomas: preliminary results of the Korean Society for Pediatric Neuro-Oncology study. Journal of neuro-oncology, 2010, Volume: 100, Issue:2 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Stem Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Combined Modality Therapy; Dacarbazine; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Korea; Male; Pons; Temozolomide; Thalidomide	2010
A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma. Neuro-oncology, 2010, Volume: 12, Issue:11 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Celecoxib; Chemotherapy, Adjuvant; Combined Modality Therapy; Dacarbazine; Female; Glioblastoma; Humans; Isotretinoin; Kaplan-Meier Estimate; Male; Middle Aged; Neurosurgical Procedures; Pyrazoles; Radiotherapy; Sulfonamides; Supratentorial Neoplasms; Temozolomide; Thalidomide; Young Adult	2010
Randomized phase II adjuvant factorial study of dose-dense temozolomide alone and in combination with isotretinoin, celecoxib, and/or thalidomide for glioblastoma. Neuro-oncology, 2015, Volume: 17, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Celecoxib; Chemotherapy, Adjuvant; Dacarbazine; Disease-Free Survival; Drug Combinations; Female; Glioblastoma; Humans; Isotretinoin; Kaplan-Meier Estimate; Male; Middle Aged; Pyrazoles; Sulfonamides; Temozolomide; Thalidomide; Young Adult	2015

Other Studies

10 other study(ies) available for temozolomide and thalidomide

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Treatment of metastatic melanoma in the brain with temozolomide and thalidomide. The Lancet. Oncology, 2001, Volume: 2, Issue:10 Topics: Adult; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Brain Neoplasms; Dacarbazine; Drug Therapy, Combination; Female; Frontal Lobe; Humans; Melanoma; Remission Induction; Temozolomide; Thalidomide	2001
Combination treatment with temozolomide and thalidomide inhibits tumor growth and angiogenesis in an orthotopic glioma model. International journal of oncology, 2006, Volume: 28, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Cell Proliferation; Dacarbazine; Gene Expression Profiling; Glioma; Humans; In Situ Nick-End Labeling; Neovascularization, Pathologic; Rats; Rats, Sprague-Dawley; Temozolomide; Thalidomide; Transplantation, Heterologous	2006
Oral regimen for metastatic neuroendocrine tumours. The Lancet. Oncology, 2006, Volume: 7, Issue:3 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dacarbazine; Humans; Neuroendocrine Tumors; Temozolomide; Thalidomide; Treatment Outcome	2006
Antiangiogenic agent, thalidomide increases the antitumor effect of single high dose irradiation (gamma knife radiosurgery) in the rat orthotopic glioma model. Oncology reports, 2006, Volume: 15, Issue:5 Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Brain Neoplasms; Cell Proliferation; Combined Modality Therapy; Dacarbazine; Disease Models, Animal; Dose-Response Relationship, Radiation; Drug Synergism; Drug Therapy, Combination; Glioma; Male; Microcirculation; Radiosurgery; Rats; Rats, Sprague-Dawley; Temozolomide; Thalidomide	2006
Predicting the myelotoxicity of chemotherapy: the use of pretreatment O6-methylguanine-DNA methyltransferase determination in peripheral blood mononuclear cells. Melanoma research, 2011, Volume: 21, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Pharmacological; Dacarbazine; Drug Administration Routes; Drug Administration Schedule; Humans; Interferon alpha-2; Interferon-alpha; Leukocytes, Mononuclear; Myeloid Cells; O(6)-Methylguanine-DNA Methyltransferase; Predictive Value of Tests; Prognosis; Recombinant Proteins; Retrospective Studies; Temozolomide; Thalidomide; Time Factors	2011
Mechanism of thalidomide to enhance cytotoxicity of temozolomide in U251-MG glioma cells in vitro. Chinese medical journal, 2009, Jun-05, Volume: 122, Issue:11 Topics: Antineoplastic Agents, Alkylating; Autophagy; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Glioma; Humans; Temozolomide; Thalidomide	2009
Treatment of aggressive pituitary tumours and carcinomas: results of a European Society of Endocrinology (ESE) survey 2016. European journal of endocrinology, 2018, Volume: 178, Issue:3 Topics: Adenoma; Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Capecitabine; Carcinoma; Carmustine; Child; Child, Preschool; Cranial Irradiation; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Endocrinology; Europe; Female; Humans; Ki-67 Antigen; Male; Middle Aged; Neoplasm Invasiveness; Neurosurgical Procedures; Pituitary Neoplasms; Societies, Medical; Surveys and Questionnaires; Temozolomide; Thalidomide; Tumor Suppressor Proteins; Young Adult	2018
Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma. Neuro-oncology, 2019, 12-17, Volume: 21, Issue:12 Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Temozolomide; Thalidomide; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays	2019